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Overview

ID MAG03927
Name TH2_bin.69
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class UBA9217
Order UBA9217
Family UBA9217
Genus JAKAHZ01
Species
Assembly information
Completeness (%) 76.05
Contamination (%) 1.44
GC content (%) 63.0
N50 (bp) 42,818
Genome size (bp) 2,598,864

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2285

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1190631_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.947e-302 934.0
TH2_k127_1190631_1 Endopeptidase La K04076 - 3.4.21.53 1.078e-237 763.0
TH2_k127_1190631_10 transcriptional regulator K03556 - - 0.0000000000000000000000000000000000000000000000000000000001851 233.0
TH2_k127_1190631_12 - - - - 0.00000000000000000000000000000000000265 149.0
TH2_k127_1190631_13 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000004975 106.0
TH2_k127_1190631_14 cellulose binding - - - 0.0000000000000000002725 106.0
TH2_k127_1190631_15 PFAM thiamineS protein - - - 0.00000000000005456 74.0
TH2_k127_1190631_16 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000001682 75.0
TH2_k127_1190631_17 Hep Hag repeat protein K07093 - - 0.000000002756 73.0
TH2_k127_1190631_2 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 554.0
TH2_k127_1190631_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 492.0
TH2_k127_1190631_4 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 417.0
TH2_k127_1190631_5 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 342.0
TH2_k127_1190631_6 PFAM MltA K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 338.0
TH2_k127_1190631_7 Putative Ig domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 362.0
TH2_k127_1190631_8 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003566 317.0
TH2_k127_1190631_9 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000001751 218.0
TH2_k127_1265002_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.964e-208 659.0
TH2_k127_1265002_1 elongation factor Tu domain 2 protein K02355 - - 1.037e-200 640.0
TH2_k127_1265002_10 TIGRFAM MoaD family protein K03636 - - 0.0000000000000000000000000006581 122.0
TH2_k127_1265002_11 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.000000000000000000000000512 110.0
TH2_k127_1265002_12 NIL - - - 0.00000000000000000000001405 104.0
TH2_k127_1265002_13 sulfur carrier activity - - - 0.000000000000000000001072 98.0
TH2_k127_1265002_14 - - - - 0.000000000000000000004472 96.0
TH2_k127_1265002_15 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.000000000003055 72.0
TH2_k127_1265002_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 550.0
TH2_k127_1265002_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 527.0
TH2_k127_1265002_4 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 518.0
TH2_k127_1265002_5 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 377.0
TH2_k127_1265002_6 Aminotransferase class I and II K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 384.0
TH2_k127_1265002_7 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 377.0
TH2_k127_1265002_8 COG0436 Aspartate tyrosine aromatic aminotransferase K12252,K14261 - 2.6.1.84 0.000000000000000000000000000000000000000000000000000509 199.0
TH2_k127_1265002_9 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000003389 125.0
TH2_k127_1272402_0 Protein of unknown function, DUF255 K06888 - - 6.117e-228 724.0
TH2_k127_1272402_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 413.0
TH2_k127_1272402_10 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000004893 121.0
TH2_k127_1272402_11 GAF domain - - - 0.000000000000000000002433 93.0
TH2_k127_1272402_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 384.0
TH2_k127_1272402_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 366.0
TH2_k127_1272402_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 355.0
TH2_k127_1272402_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 283.0
TH2_k127_1272402_6 sensor histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000002585 246.0
TH2_k127_1272402_8 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000003676 138.0
TH2_k127_1272402_9 YtkA-like - - - 0.0000000000000000000000000000435 120.0
TH2_k127_1291706_0 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 310.0
TH2_k127_1291706_2 Cysteine rich repeat - - - 0.0000000000000000000000000000000000000000000002464 173.0
TH2_k127_1291706_3 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000004902 167.0
TH2_k127_1291706_4 - - - - 0.0000000000000000000000000000000000000000003342 169.0
TH2_k127_1291706_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000001646 61.0
TH2_k127_1291706_6 Cysteine rich repeat K06816 - - 0.000105 50.0
TH2_k127_131273_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 4.529e-225 707.0
TH2_k127_131597_0 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 574.0
TH2_k127_131597_1 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002008 254.0
TH2_k127_131597_2 Protein of unknown function (DUF3015) - - - 0.000000000000000000000000000000000000001977 149.0
TH2_k127_131597_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0003282 49.0
TH2_k127_1368938_0 ABC transporter C-terminal domain K15738 - - 1.45e-238 753.0
TH2_k127_1368938_1 fibronectin type III domain protein K06882 - - 4.272e-208 694.0
TH2_k127_1368938_10 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000005547 261.0
TH2_k127_1368938_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000002637 263.0
TH2_k127_1368938_12 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000007865 250.0
TH2_k127_1368938_13 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000002959 219.0
TH2_k127_1368938_14 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000001575 220.0
TH2_k127_1368938_15 auxin-activated signaling pathway K07088 - - 0.000000000000000000000000000000000000000000000000000000000004416 219.0
TH2_k127_1368938_16 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000007151 177.0
TH2_k127_1368938_17 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000001974 188.0
TH2_k127_1368938_18 - - - - 0.0000000000000000000000000000000000000000002756 164.0
TH2_k127_1368938_19 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000004802 159.0
TH2_k127_1368938_2 PFAM Major Facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 531.0
TH2_k127_1368938_20 PFAM methyltransferase K15460 - 2.1.1.223 0.000000000000000000000000000000000000000005737 164.0
TH2_k127_1368938_21 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000001038 151.0
TH2_k127_1368938_22 PEP-CTERM motif - - - 0.00000000000000000000000000000002411 135.0
TH2_k127_1368938_23 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000005177 140.0
TH2_k127_1368938_24 PFAM response regulator receiver - - - 0.00000000000000000000000000000006456 133.0
TH2_k127_1368938_25 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000001047 130.0
TH2_k127_1368938_26 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.0000000000000000000000000002476 117.0
TH2_k127_1368938_27 Protein of unknown function (DUF721) - - - 0.000000000000000000004961 98.0
TH2_k127_1368938_28 regulation of response to stimulus K02014,K13730 - - 0.0000000000000005027 92.0
TH2_k127_1368938_29 PFAM Rubrerythrin - - - 0.000000000000003738 83.0
TH2_k127_1368938_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 494.0
TH2_k127_1368938_32 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000001178 65.0
TH2_k127_1368938_33 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.000000001275 71.0
TH2_k127_1368938_34 phosphorelay signal transduction system - - - 0.00000001385 66.0
TH2_k127_1368938_35 - - - - 0.00000002486 56.0
TH2_k127_1368938_38 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000006492 61.0
TH2_k127_1368938_39 - - - - 0.00006582 50.0
TH2_k127_1368938_4 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 471.0
TH2_k127_1368938_5 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 473.0
TH2_k127_1368938_6 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 452.0
TH2_k127_1368938_7 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 353.0
TH2_k127_1368938_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 356.0
TH2_k127_1368938_9 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002159 259.0
TH2_k127_1373013_0 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 400.0
TH2_k127_1373013_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 383.0
TH2_k127_1373013_10 TM2 domain - - - 0.00006627 54.0
TH2_k127_1373013_2 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000004167 264.0
TH2_k127_1373013_3 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000000000000000000000000000000000000000000041 222.0
TH2_k127_1373013_4 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000004422 194.0
TH2_k127_1373013_5 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000766 197.0
TH2_k127_1373013_6 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000000000000004262 149.0
TH2_k127_1373013_7 - - - - 0.0000000000000000000000000000000000001813 154.0
TH2_k127_1373013_8 Protein of unknown function (DUF2628) - - - 0.000000000000001002 87.0
TH2_k127_1373013_9 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000002895 76.0
TH2_k127_1373929_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000379 201.0
TH2_k127_1373929_1 - - - - 0.000000000000000000000000000000000000000000006998 184.0
TH2_k127_1373929_2 cytochrome C - - - 0.000000000000000000000002002 104.0
TH2_k127_1373929_3 Sensor histidine kinase, HAMP and PAS domain-containing - - - 0.000002427 55.0
TH2_k127_14529_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 8.767e-318 981.0
TH2_k127_14529_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 595.0
TH2_k127_14529_2 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 473.0
TH2_k127_14529_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 394.0
TH2_k127_14529_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 380.0
TH2_k127_14529_5 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 321.0
TH2_k127_14529_6 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002381 252.0
TH2_k127_14529_7 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000001452 115.0
TH2_k127_14529_8 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000009738 87.0
TH2_k127_14529_9 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000006813 79.0
TH2_k127_1575210_0 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 494.0
TH2_k127_1575210_1 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000003245 197.0
TH2_k127_1575210_2 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000000000000000009226 163.0
TH2_k127_1594065_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 3.5e-323 1010.0
TH2_k127_1594065_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.149e-319 998.0
TH2_k127_1594065_10 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 451.0
TH2_k127_1594065_11 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 404.0
TH2_k127_1594065_12 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 388.0
TH2_k127_1594065_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 352.0
TH2_k127_1594065_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 328.0
TH2_k127_1594065_15 Clp protease K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 318.0
TH2_k127_1594065_16 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 308.0
TH2_k127_1594065_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 298.0
TH2_k127_1594065_18 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002776 287.0
TH2_k127_1594065_19 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005075 285.0
TH2_k127_1594065_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 3.934e-292 905.0
TH2_k127_1594065_20 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000002081 237.0
TH2_k127_1594065_21 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000001165 224.0
TH2_k127_1594065_22 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000002575 207.0
TH2_k127_1594065_23 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000005267 205.0
TH2_k127_1594065_24 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000001387 198.0
TH2_k127_1594065_25 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000002748 205.0
TH2_k127_1594065_26 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000245 184.0
TH2_k127_1594065_27 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000000009252 159.0
TH2_k127_1594065_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000001803 141.0
TH2_k127_1594065_29 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000002543 101.0
TH2_k127_1594065_3 PFAM Transketolase K00615 - 2.2.1.1 2.94e-239 757.0
TH2_k127_1594065_30 regulation of DNA repair K03565,K19002 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 0.000000000000000000002686 100.0
TH2_k127_1594065_31 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000125 96.0
TH2_k127_1594065_32 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000001601 78.0
TH2_k127_1594065_33 ATP synthase, subunit b - - - 0.000000003586 64.0
TH2_k127_1594065_34 alginic acid biosynthetic process K10297 - - 0.00000004397 59.0
TH2_k127_1594065_35 - - - - 0.0000008961 56.0
TH2_k127_1594065_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.061e-202 638.0
TH2_k127_1594065_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 4.392e-194 612.0
TH2_k127_1594065_6 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 560.0
TH2_k127_1594065_7 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 512.0
TH2_k127_1594065_8 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 488.0
TH2_k127_1594065_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 473.0
TH2_k127_1689042_0 PFAM peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0 1199.0
TH2_k127_1689042_1 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 622.0
TH2_k127_1689042_10 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 313.0
TH2_k127_1689042_11 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006571 289.0
TH2_k127_1689042_12 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007564 250.0
TH2_k127_1689042_13 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002199 238.0
TH2_k127_1689042_14 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009941 244.0
TH2_k127_1689042_15 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001877 238.0
TH2_k127_1689042_16 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000001258 232.0
TH2_k127_1689042_17 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000008851 213.0
TH2_k127_1689042_18 Domain of unknown function (DUF4824) - - - 0.0000000000000000000000000000000000000000000000000000000002349 216.0
TH2_k127_1689042_19 Putative metal-binding motif - - - 0.00000000000000000000000000000000000000000000000000001329 197.0
TH2_k127_1689042_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 576.0
TH2_k127_1689042_20 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000000001004 184.0
TH2_k127_1689042_21 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000001623 183.0
TH2_k127_1689042_22 MarR family transcriptional K15973 - - 0.00000000000000000000000000000000000000000000000005688 183.0
TH2_k127_1689042_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000003777 169.0
TH2_k127_1689042_24 - - - - 0.00000000000000000000000000000000000000000005098 164.0
TH2_k127_1689042_25 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000561 164.0
TH2_k127_1689042_26 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000001617 160.0
TH2_k127_1689042_27 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.000000000000000000000000000000000000003601 151.0
TH2_k127_1689042_28 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000002697 149.0
TH2_k127_1689042_29 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000002277 139.0
TH2_k127_1689042_3 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 513.0
TH2_k127_1689042_30 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.00000000000000000000000000000006239 133.0
TH2_k127_1689042_31 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000004622 122.0
TH2_k127_1689042_32 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000001738 119.0
TH2_k127_1689042_33 DUF218 domain - - - 0.000000000000000000000001457 113.0
TH2_k127_1689042_34 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000659 102.0
TH2_k127_1689042_35 - - - - 0.000000000000000000107 95.0
TH2_k127_1689042_36 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.000000000000000004147 95.0
TH2_k127_1689042_37 Protein of unknown function (DUF1648) - - - 0.0000000000000105 81.0
TH2_k127_1689042_39 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.000000005566 66.0
TH2_k127_1689042_4 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 436.0
TH2_k127_1689042_40 GAF domain - - - 0.00000002971 64.0
TH2_k127_1689042_41 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000244 60.0
TH2_k127_1689042_5 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 433.0
TH2_k127_1689042_6 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 412.0
TH2_k127_1689042_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 396.0
TH2_k127_1689042_8 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 375.0
TH2_k127_1689042_9 HlyD membrane-fusion protein of T1SS K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 341.0
TH2_k127_1689495_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 461.0
TH2_k127_1689495_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 302.0
TH2_k127_1689495_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 321.0
TH2_k127_1689495_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 291.0
TH2_k127_1689495_4 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000001556 256.0
TH2_k127_1689495_5 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000006334 176.0
TH2_k127_1689495_6 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000001026 170.0
TH2_k127_1689495_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000004216 159.0
TH2_k127_1689495_8 dUTP biosynthetic process K01494 - 3.5.4.13 0.0000000000000000000000000000000000008016 139.0
TH2_k127_1689495_9 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000001059 131.0
TH2_k127_1911738_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1027.0
TH2_k127_1911738_1 Aconitase C-terminal domain K01681 - 4.2.1.3 4.254e-321 994.0
TH2_k127_1911738_10 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 383.0
TH2_k127_1911738_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 346.0
TH2_k127_1911738_12 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 313.0
TH2_k127_1911738_13 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003129 265.0
TH2_k127_1911738_14 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002058 271.0
TH2_k127_1911738_15 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000000000000000000000001976 216.0
TH2_k127_1911738_16 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000008932 175.0
TH2_k127_1911738_17 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000009819 153.0
TH2_k127_1911738_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.711e-245 766.0
TH2_k127_1911738_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 3.497e-206 653.0
TH2_k127_1911738_4 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 545.0
TH2_k127_1911738_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 529.0
TH2_k127_1911738_6 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 524.0
TH2_k127_1911738_7 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 521.0
TH2_k127_1911738_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 452.0
TH2_k127_1911738_9 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 411.0
TH2_k127_197808_0 PFAM Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 308.0
TH2_k127_197808_1 Histidine kinase - - - 0.000000000000000000000000000009583 138.0
TH2_k127_197808_2 - - - - 0.0000000000000006976 79.0
TH2_k127_2036211_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2063.0
TH2_k127_2036211_1 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1695.0
TH2_k127_2036211_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000295 90.0
TH2_k127_2036211_11 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000001616 89.0
TH2_k127_2036211_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000001991 81.0
TH2_k127_2036211_13 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000004935 59.0
TH2_k127_2036211_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1082.0
TH2_k127_2036211_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 324.0
TH2_k127_2036211_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000127 234.0
TH2_k127_2036211_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000003464 230.0
TH2_k127_2036211_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000001216 217.0
TH2_k127_2036211_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000254 214.0
TH2_k127_2036211_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000005685 175.0
TH2_k127_2036211_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000002126 173.0
TH2_k127_208133_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 4.357e-318 991.0
TH2_k127_208133_1 PFAM ferredoxin-dependent glutamate synthase - - - 2.08e-295 913.0
TH2_k127_208133_10 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 614.0
TH2_k127_208133_11 Ammonium Transporter K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 586.0
TH2_k127_208133_12 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 582.0
TH2_k127_208133_13 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 573.0
TH2_k127_208133_14 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 563.0
TH2_k127_208133_15 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 510.0
TH2_k127_208133_16 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 497.0
TH2_k127_208133_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 488.0
TH2_k127_208133_18 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 520.0
TH2_k127_208133_19 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 473.0
TH2_k127_208133_2 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 2.111e-292 905.0
TH2_k127_208133_20 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 472.0
TH2_k127_208133_21 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 466.0
TH2_k127_208133_22 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 458.0
TH2_k127_208133_23 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 451.0
TH2_k127_208133_24 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 457.0
TH2_k127_208133_25 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 447.0
TH2_k127_208133_26 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 460.0
TH2_k127_208133_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 441.0
TH2_k127_208133_28 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 436.0
TH2_k127_208133_29 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 405.0
TH2_k127_208133_3 FMN binding - - - 3.746e-277 858.0
TH2_k127_208133_30 glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 400.0
TH2_k127_208133_31 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 406.0
TH2_k127_208133_32 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 395.0
TH2_k127_208133_33 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 392.0
TH2_k127_208133_34 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 394.0
TH2_k127_208133_35 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 383.0
TH2_k127_208133_36 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 355.0
TH2_k127_208133_37 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 362.0
TH2_k127_208133_38 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 334.0
TH2_k127_208133_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 336.0
TH2_k127_208133_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.539e-232 736.0
TH2_k127_208133_40 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 332.0
TH2_k127_208133_41 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 295.0
TH2_k127_208133_42 PFAM Cytochrome b5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001072 290.0
TH2_k127_208133_43 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008495 278.0
TH2_k127_208133_44 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000001428 273.0
TH2_k127_208133_45 Signal transduction histidine kinase, nitrogen specific, NtrB K07708,K10942 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004589 270.0
TH2_k127_208133_46 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002483 258.0
TH2_k127_208133_47 PFAM NADH Ubiquinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000419 244.0
TH2_k127_208133_48 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002071 246.0
TH2_k127_208133_49 PFAM HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000002086 244.0
TH2_k127_208133_5 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 9.534e-223 726.0
TH2_k127_208133_50 CMP dCMP deaminase, zinc-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000006118 228.0
TH2_k127_208133_51 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000002859 221.0
TH2_k127_208133_52 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000724 210.0
TH2_k127_208133_53 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000000000000000000000000000003275 200.0
TH2_k127_208133_54 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15268 - - 0.000000000000000000000000000000000000000000000000008839 192.0
TH2_k127_208133_55 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000001085 190.0
TH2_k127_208133_56 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000005736 181.0
TH2_k127_208133_57 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0036094,GO:0042592,GO:0043167,GO:0043168,GO:0044237,GO:0044425,GO:0044464,GO:0045333,GO:0048037,GO:0048878,GO:0050136,GO:0050660,GO:0050662,GO:0050801,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:0098771,GO:0098796,GO:1901265,GO:1901363,GO:1902494 1.6.99.3 0.0000000000000000000000000000000000000000000000002571 194.0
TH2_k127_208133_58 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000002557 171.0
TH2_k127_208133_59 cyclic nucleotide binding K01420,K10716,K10914 - - 0.0000000000000000000000000000000000000000000000364 177.0
TH2_k127_208133_6 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.166e-217 696.0
TH2_k127_208133_60 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000001043 174.0
TH2_k127_208133_61 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000057 150.0
TH2_k127_208133_62 methyltransferase - - - 0.00000000000000000000000000000000000009153 149.0
TH2_k127_208133_63 - - - - 0.0000000000000000000000000000000000006719 145.0
TH2_k127_208133_64 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000006199 150.0
TH2_k127_208133_65 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000001443 143.0
TH2_k127_208133_66 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000002476 139.0
TH2_k127_208133_67 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000002629 143.0
TH2_k127_208133_68 - - - - 0.00000000000000000000000000000001158 132.0
TH2_k127_208133_69 4Fe-4S binding domain - - - 0.00000000000000000000000000000002585 140.0
TH2_k127_208133_7 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 4.55e-209 669.0
TH2_k127_208133_70 - - - - 0.00000000000000000000000000000008915 130.0
TH2_k127_208133_71 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000002601 136.0
TH2_k127_208133_72 Thioesterase superfamily - - - 0.0000000000000000000000000000477 123.0
TH2_k127_208133_73 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000001979 114.0
TH2_k127_208133_74 Nlp p60 protein K13694,K13695 - 3.4.17.13 0.000000000000000000000000003088 127.0
TH2_k127_208133_75 Cbs domain - - - 0.0000000000000000000000004407 113.0
TH2_k127_208133_76 Protein of unknown function (DUF2892) - - - 0.000000000000000000000002166 104.0
TH2_k127_208133_77 Protein of unknown function (DUF3795) - - - 0.000000000000000000000002377 108.0
TH2_k127_208133_78 - - - - 0.0000000000000000000002447 108.0
TH2_k127_208133_79 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000002365 94.0
TH2_k127_208133_8 Belongs to the RtcB family K14415 - 6.5.1.3 3.773e-202 639.0
TH2_k127_208133_80 Crp-like helix-turn-helix domain K10914 - - 0.00000000000000000008395 95.0
TH2_k127_208133_81 - - - - 0.0000000000000000002533 89.0
TH2_k127_208133_82 Cytochrome c7 and related cytochrome c - - - 0.00000000000000001312 86.0
TH2_k127_208133_83 Thioredoxin domain - - - 0.00000000000000003327 93.0
TH2_k127_208133_85 AhpC/TSA family K03386 - 1.11.1.15 0.000000000000000373 80.0
TH2_k127_208133_86 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000000003728 83.0
TH2_k127_208133_87 response regulator, receiver K00384 - 1.8.1.9 0.000000000001909 77.0
TH2_k127_208133_88 12 heme-binding sites - - - 0.000000000006612 71.0
TH2_k127_208133_89 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000007993 73.0
TH2_k127_208133_9 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 627.0
TH2_k127_208133_90 Cupin 2, conserved barrel domain protein - - - 0.0000000001189 66.0
TH2_k127_208133_91 HEPN domain - - - 0.0000000008905 65.0
TH2_k127_208133_93 Tetratricopeptide repeats - - - 0.0000004776 58.0
TH2_k127_208133_94 Protein of unknown function (DUF1523) - - - 0.000001182 55.0
TH2_k127_208133_96 Tetratricopeptide repeat - - - 0.0002001 52.0
TH2_k127_208133_97 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.0002646 46.0
TH2_k127_227822_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 5.807e-235 752.0
TH2_k127_227822_1 coenzyme F420 binding K00275 - 1.4.3.5 0.0000000000000000000000000000000000000001076 155.0
TH2_k127_227822_2 glyoxalase III activity - - - 0.000000000000000000000000000000000000009026 164.0
TH2_k127_227822_3 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000007092 100.0
TH2_k127_2312588_0 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 436.0
TH2_k127_2312588_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 319.0
TH2_k127_2312588_10 Protein of unknown function (DUF1698) - - - 0.00000000000000001482 94.0
TH2_k127_2312588_11 - - - - 0.0000001429 63.0
TH2_k127_2312588_12 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.000002867 59.0
TH2_k127_2312588_14 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00008185 48.0
TH2_k127_2312588_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 310.0
TH2_k127_2312588_3 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 321.0
TH2_k127_2312588_4 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 318.0
TH2_k127_2312588_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 304.0
TH2_k127_2312588_6 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007444 272.0
TH2_k127_2312588_7 cytochrome c biogenesis protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000003457 224.0
TH2_k127_2312588_8 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000008583 196.0
TH2_k127_2312588_9 B12 binding domain - - - 0.00000000000000000000001869 115.0
TH2_k127_2329038_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 556.0
TH2_k127_2329038_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 492.0
TH2_k127_2329038_10 Belongs to the cysteine synthase cystathionine beta- synthase family K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 344.0
TH2_k127_2329038_11 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 340.0
TH2_k127_2329038_12 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 280.0
TH2_k127_2329038_13 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000000000000001303 224.0
TH2_k127_2329038_14 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000007184 207.0
TH2_k127_2329038_15 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000000000001263 199.0
TH2_k127_2329038_16 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000001174 178.0
TH2_k127_2329038_17 NosL - - - 0.0000000000000000000000000000000000000000000122 168.0
TH2_k127_2329038_18 NosL - - - 0.000000000000000000000000000000000000000002936 166.0
TH2_k127_2329038_19 Nitroreductase family - - - 0.0000000000000000000000000000000000001597 149.0
TH2_k127_2329038_2 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 499.0
TH2_k127_2329038_20 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000001006 147.0
TH2_k127_2329038_21 PFAM chemotaxis sensory transducer K03406,K05874 - - 0.0000000000000000000000000000000004276 137.0
TH2_k127_2329038_22 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000000001485 133.0
TH2_k127_2329038_23 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000003889 121.0
TH2_k127_2329038_24 monooxygenase activity - - - 0.000000000000000000000008698 107.0
TH2_k127_2329038_25 monooxygenase activity - - - 0.0000000000002309 71.0
TH2_k127_2329038_26 - - - - 0.0000000000004931 79.0
TH2_k127_2329038_27 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.000000000004174 72.0
TH2_k127_2329038_28 Cytochrome c - - - 0.000000000005066 70.0
TH2_k127_2329038_29 FabA-like domain K02372 - 4.2.1.59 0.0000003189 59.0
TH2_k127_2329038_3 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 481.0
TH2_k127_2329038_30 isomerase B K01808 - 5.3.1.6 0.0000007824 61.0
TH2_k127_2329038_32 ATPase involved in DNA repair K03546 - - 0.00001639 54.0
TH2_k127_2329038_33 Type II/IV secretion system protein K02454,K02652 - - 0.00005834 50.0
TH2_k127_2329038_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 457.0
TH2_k127_2329038_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 466.0
TH2_k127_2329038_6 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 451.0
TH2_k127_2329038_7 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 432.0
TH2_k127_2329038_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 378.0
TH2_k127_2329038_9 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 362.0
TH2_k127_2354047_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1016.0
TH2_k127_2354047_1 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000001411 224.0
TH2_k127_2354047_2 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000002233 177.0
TH2_k127_2402008_0 glycolate transport K14393 - - 3.014e-251 790.0
TH2_k127_2402008_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00007002 48.0
TH2_k127_2415307_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 346.0
TH2_k127_2415307_1 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 334.0
TH2_k127_2415307_2 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 317.0
TH2_k127_2415307_3 regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000009846 205.0
TH2_k127_2415307_4 domain, Protein K13735,K20276 - - 0.0000000000000001038 89.0
TH2_k127_2415307_5 - - - - 0.00000002854 64.0
TH2_k127_2415307_6 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.000002287 57.0
TH2_k127_245360_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.277e-314 994.0
TH2_k127_245360_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001642 281.0
TH2_k127_245360_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008777 280.0
TH2_k127_245360_3 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000001744 211.0
TH2_k127_245360_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000008803 176.0
TH2_k127_245360_5 Enoyl-CoA hydratase/isomerase K13767 - 4.2.1.17 0.000000000000000000000000000000000000000008977 163.0
TH2_k127_245360_6 Belongs to the UPF0250 family K09158 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000002078 95.0
TH2_k127_245360_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000003536 90.0
TH2_k127_2454222_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.215e-296 930.0
TH2_k127_2454222_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 574.0
TH2_k127_2454222_10 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 311.0
TH2_k127_2454222_11 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000001227 264.0
TH2_k127_2454222_12 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000572 230.0
TH2_k127_2454222_13 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000000002328 198.0
TH2_k127_2454222_14 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000003682 196.0
TH2_k127_2454222_15 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000000001277 157.0
TH2_k127_2454222_16 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000004091 144.0
TH2_k127_2454222_17 - - - - 0.0000000000000000000000000000001125 132.0
TH2_k127_2454222_18 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0000000000000000000000001686 110.0
TH2_k127_2454222_19 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000002997 101.0
TH2_k127_2454222_2 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 501.0
TH2_k127_2454222_20 - - - - 0.000000000000000001503 94.0
TH2_k127_2454222_21 Domain of unknown function (DUF4136) - - - 0.00000000000000001026 91.0
TH2_k127_2454222_22 META domain - - - 0.0000000000000002066 85.0
TH2_k127_2454222_23 response to heat K03668 - - 0.0000000000000006949 85.0
TH2_k127_2454222_24 - - - - 0.0000000000000007425 87.0
TH2_k127_2454222_25 - - - - 0.000000000000009964 81.0
TH2_k127_2454222_26 PFAM PRC-barrel domain - - - 0.000000007482 63.0
TH2_k127_2454222_27 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.000000213 53.0
TH2_k127_2454222_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 486.0
TH2_k127_2454222_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 481.0
TH2_k127_2454222_5 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 437.0
TH2_k127_2454222_6 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 407.0
TH2_k127_2454222_7 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 380.0
TH2_k127_2454222_8 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 365.0
TH2_k127_2454222_9 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 317.0
TH2_k127_2717314_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1578.0
TH2_k127_2717314_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1086.0
TH2_k127_2717314_10 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 531.0
TH2_k127_2717314_11 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 507.0
TH2_k127_2717314_12 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 487.0
TH2_k127_2717314_13 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 465.0
TH2_k127_2717314_14 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 447.0
TH2_k127_2717314_15 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 437.0
TH2_k127_2717314_16 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 415.0
TH2_k127_2717314_17 peptidoglycan biosynthetic process K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 412.0
TH2_k127_2717314_18 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 397.0
TH2_k127_2717314_19 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 361.0
TH2_k127_2717314_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 9.175e-267 832.0
TH2_k127_2717314_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 379.0
TH2_k127_2717314_21 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 368.0
TH2_k127_2717314_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 341.0
TH2_k127_2717314_23 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 320.0
TH2_k127_2717314_24 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 302.0
TH2_k127_2717314_25 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 292.0
TH2_k127_2717314_26 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 293.0
TH2_k127_2717314_27 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006804 287.0
TH2_k127_2717314_28 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007948 297.0
TH2_k127_2717314_29 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000004349 264.0
TH2_k127_2717314_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.202e-229 722.0
TH2_k127_2717314_30 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001005 256.0
TH2_k127_2717314_31 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000007517 248.0
TH2_k127_2717314_32 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001655 253.0
TH2_k127_2717314_33 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000001687 243.0
TH2_k127_2717314_34 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000009717 238.0
TH2_k127_2717314_35 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000008813 234.0
TH2_k127_2717314_36 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000006398 214.0
TH2_k127_2717314_37 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000007981 206.0
TH2_k127_2717314_38 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000128 192.0
TH2_k127_2717314_39 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000004278 162.0
TH2_k127_2717314_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 9.536e-222 705.0
TH2_k127_2717314_40 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000004836 156.0
TH2_k127_2717314_41 Thioredoxin-like - - - 0.00000000000000000000000000000000007565 140.0
TH2_k127_2717314_42 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000000000003824 130.0
TH2_k127_2717314_43 - - - - 0.00000000000000000000000000003258 128.0
TH2_k127_2717314_44 - - - - 0.0000000000000000000000002845 110.0
TH2_k127_2717314_45 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000001275 113.0
TH2_k127_2717314_46 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00000000000000000001086 100.0
TH2_k127_2717314_47 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.0000000000000001343 94.0
TH2_k127_2717314_48 Domain of unknown function (DUF4388) - - - 0.000000000000002053 82.0
TH2_k127_2717314_49 Domain of unknown function (DUF4253) - - - 0.000000000000009171 85.0
TH2_k127_2717314_5 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.557e-213 675.0
TH2_k127_2717314_50 PFAM NosL family protein - - - 0.00000000001604 70.0
TH2_k127_2717314_51 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000003059 65.0
TH2_k127_2717314_52 Domain of unknown function (DUF3786) - - - 0.00000004638 62.0
TH2_k127_2717314_56 signal transduction histidine kinase - - - 0.0003042 51.0
TH2_k127_2717314_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.895e-199 632.0
TH2_k127_2717314_7 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 591.0
TH2_k127_2717314_8 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 597.0
TH2_k127_2717314_9 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 546.0
TH2_k127_273382_0 NADH flavin oxidoreductase NADH oxidase K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 607.0
TH2_k127_273382_1 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 529.0
TH2_k127_273382_10 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000005587 171.0
TH2_k127_273382_11 - - - - 0.00000000000000000000000000000000000000001031 160.0
TH2_k127_273382_12 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000009481 126.0
TH2_k127_273382_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 451.0
TH2_k127_273382_3 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 402.0
TH2_k127_273382_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 366.0
TH2_k127_273382_5 - - - - 0.00000000000000000000000000000000000000000000000000000003157 205.0
TH2_k127_273382_6 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000007689 203.0
TH2_k127_273382_7 YHS domain protein - - - 0.000000000000000000000000000000000000000000000000002708 192.0
TH2_k127_273382_8 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000001756 177.0
TH2_k127_273382_9 protocatechuate 3,4-dioxygenase - - - 0.00000000000000000000000000000000000000000000003058 176.0
TH2_k127_2842483_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.082e-274 861.0
TH2_k127_2842483_1 Telomere recombination K04656 - - 7.491e-232 745.0
TH2_k127_2842483_10 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 423.0
TH2_k127_2842483_11 TIGRFAM MATE efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 400.0
TH2_k127_2842483_12 formate dehydrogenase, beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 384.0
TH2_k127_2842483_13 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 376.0
TH2_k127_2842483_14 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 335.0
TH2_k127_2842483_15 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 312.0
TH2_k127_2842483_16 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 312.0
TH2_k127_2842483_17 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000002973 263.0
TH2_k127_2842483_18 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004085 255.0
TH2_k127_2842483_19 TonB-dependent Receptor Plug Domain K16092 - - 0.0000000000000000000000000000000000000000000000000000000000003172 234.0
TH2_k127_2842483_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 2.078e-231 724.0
TH2_k127_2842483_20 histidine kinase HAMP region domain protein K07710 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000003692 229.0
TH2_k127_2842483_21 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001443 232.0
TH2_k127_2842483_22 PEP-CTERM motif - - - 0.00000000000000000000000000000000000000000000000000000000002378 213.0
TH2_k127_2842483_23 Efflux ABC transporter, permease protein K02004 - - 0.000000000000000000000000000000000000000000000000000000001019 216.0
TH2_k127_2842483_24 - - - - 0.000000000000000000000000000000000000000000000000000002604 196.0
TH2_k127_2842483_25 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000003548 194.0
TH2_k127_2842483_26 protein with SCP PR1 domains - - - 0.0000000000000000000000000000000000000000000000000006962 191.0
TH2_k127_2842483_27 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000205 183.0
TH2_k127_2842483_28 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000005738 189.0
TH2_k127_2842483_29 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000001855 165.0
TH2_k127_2842483_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.582e-228 734.0
TH2_k127_2842483_30 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000006491 160.0
TH2_k127_2842483_31 - - - - 0.000000000000000000000000000000000002707 140.0
TH2_k127_2842483_32 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 0.000000000000000000000000001421 112.0
TH2_k127_2842483_33 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.00000000000000000000000002772 112.0
TH2_k127_2842483_34 Solute carrier family 35 - - - 0.0000000000000000000001072 108.0
TH2_k127_2842483_35 Protein of unknown function (DUF433) - - - 0.0000000000000000000002474 108.0
TH2_k127_2842483_36 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000002117 92.0
TH2_k127_2842483_37 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000009852 78.0
TH2_k127_2842483_38 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000004688 77.0
TH2_k127_2842483_39 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000001343 71.0
TH2_k127_2842483_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 7.68e-211 662.0
TH2_k127_2842483_40 - - - - 0.00000002001 59.0
TH2_k127_2842483_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 558.0
TH2_k127_2842483_6 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 498.0
TH2_k127_2842483_7 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 498.0
TH2_k127_2842483_8 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 437.0
TH2_k127_2842483_9 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 428.0
TH2_k127_2981889_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.467e-250 778.0
TH2_k127_2981889_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.115e-250 783.0
TH2_k127_2981889_10 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 452.0
TH2_k127_2981889_11 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 435.0
TH2_k127_2981889_12 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 428.0
TH2_k127_2981889_13 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 394.0
TH2_k127_2981889_14 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 403.0
TH2_k127_2981889_15 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 381.0
TH2_k127_2981889_16 Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 350.0
TH2_k127_2981889_17 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 353.0
TH2_k127_2981889_18 S-layer homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 346.0
TH2_k127_2981889_19 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 334.0
TH2_k127_2981889_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 1.78e-218 685.0
TH2_k127_2981889_20 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 319.0
TH2_k127_2981889_21 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 329.0
TH2_k127_2981889_22 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 324.0
TH2_k127_2981889_23 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 327.0
TH2_k127_2981889_24 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 316.0
TH2_k127_2981889_25 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 305.0
TH2_k127_2981889_26 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 308.0
TH2_k127_2981889_27 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 299.0
TH2_k127_2981889_28 Psort location CytoplasmicMembrane, score K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 288.0
TH2_k127_2981889_29 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 287.0
TH2_k127_2981889_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.091e-213 682.0
TH2_k127_2981889_30 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000007656 263.0
TH2_k127_2981889_31 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002586 268.0
TH2_k127_2981889_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001601 261.0
TH2_k127_2981889_33 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004032 251.0
TH2_k127_2981889_34 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005571 246.0
TH2_k127_2981889_35 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000003684 245.0
TH2_k127_2981889_36 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000077 237.0
TH2_k127_2981889_37 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000008569 232.0
TH2_k127_2981889_38 - - - - 0.000000000000000000000000000000000000000000000000000000000004956 222.0
TH2_k127_2981889_39 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000002165 211.0
TH2_k127_2981889_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 592.0
TH2_k127_2981889_40 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000007714 202.0
TH2_k127_2981889_41 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000003302 198.0
TH2_k127_2981889_42 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000006657 182.0
TH2_k127_2981889_43 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000008352 180.0
TH2_k127_2981889_44 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000001972 172.0
TH2_k127_2981889_45 FecR protein - - - 0.000000000000000000000000000000000000000000001595 174.0
TH2_k127_2981889_46 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000225 176.0
TH2_k127_2981889_47 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000005022 162.0
TH2_k127_2981889_48 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000002485 167.0
TH2_k127_2981889_49 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000009268 148.0
TH2_k127_2981889_5 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 574.0
TH2_k127_2981889_50 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000001374 122.0
TH2_k127_2981889_51 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000567 123.0
TH2_k127_2981889_52 Pfam:N_methyl_2 K02650 - - 0.00000000000000000000000007045 115.0
TH2_k127_2981889_53 cheY-homologous receiver domain - - - 0.0000000000000000000000004215 110.0
TH2_k127_2981889_54 FixH - - - 0.00000000000000000000002322 106.0
TH2_k127_2981889_55 electron transfer activity K05337,K17247 - - 0.0000000000000000000003123 97.0
TH2_k127_2981889_56 Transglutaminase-like superfamily - - - 0.000000000000000000008337 106.0
TH2_k127_2981889_57 PFAM cytochrome c class I - - - 0.00000000000000004502 87.0
TH2_k127_2981889_58 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.0000000000000002545 83.0
TH2_k127_2981889_59 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.00000000000001457 74.0
TH2_k127_2981889_6 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 572.0
TH2_k127_2981889_60 dolichyl monophosphate biosynthetic process - - - 0.00000000000001794 83.0
TH2_k127_2981889_61 domain protein K20276 - - 0.000000001004 71.0
TH2_k127_2981889_62 Protein of unknown function (DUF2892) - - - 0.000000005184 63.0
TH2_k127_2981889_63 carbon monoxide dehydrogenase - - - 0.0000003042 58.0
TH2_k127_2981889_64 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00001088 55.0
TH2_k127_2981889_65 Domain of unknown function (DUF4388) - - - 0.00002796 54.0
TH2_k127_2981889_66 Carboxypeptidase regulatory-like domain - - - 0.00003137 55.0
TH2_k127_2981889_67 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0004873 46.0
TH2_k127_2981889_68 COG0607 Rhodanese-related sulfurtransferase - - - 0.0008386 48.0
TH2_k127_2981889_7 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 521.0
TH2_k127_2981889_8 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 501.0
TH2_k127_2981889_9 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 476.0
TH2_k127_3149348_0 Tim44 K02117,K08678,K11646,K15539,K17835,K21636 - 1.1.98.6,1.4.1.24,3.6.3.14,3.6.3.15,4.1.1.35,4.1.99.20 8.466e-226 734.0
TH2_k127_3149348_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 614.0
TH2_k127_3149348_10 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001328 247.0
TH2_k127_3149348_11 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003076 226.0
TH2_k127_3149348_12 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000008484 214.0
TH2_k127_3149348_13 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000009522 185.0
TH2_k127_3149348_14 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000000000000003564 180.0
TH2_k127_3149348_15 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000003863 171.0
TH2_k127_3149348_16 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.000000000000000000000000000000000007331 147.0
TH2_k127_3149348_17 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000105 121.0
TH2_k127_3149348_18 TIGRFAM 4-oxalocrotonate tautomerase family enzyme K01821 - 5.3.2.6 0.00000000000000000000000001413 113.0
TH2_k127_3149348_19 Fimbrial assembly family protein K02461 - - 0.00000000000000000000003202 113.0
TH2_k127_3149348_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 586.0
TH2_k127_3149348_20 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000003238 101.0
TH2_k127_3149348_21 Omptin family - - - 0.0000000000000000000003767 109.0
TH2_k127_3149348_23 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000008022 93.0
TH2_k127_3149348_24 Type II secretion system (T2SS), protein M K02462 - - 0.00000000000000093 84.0
TH2_k127_3149348_25 Prokaryotic N-terminal methylation motif - - - 0.000000000003508 73.0
TH2_k127_3149348_26 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.00000001973 62.0
TH2_k127_3149348_27 Type II secretion system (T2SS), protein K K02460 - - 0.0000007356 60.0
TH2_k127_3149348_28 - - - - 0.000001296 59.0
TH2_k127_3149348_29 PEP-CTERM motif - - - 0.0002332 50.0
TH2_k127_3149348_3 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 445.0
TH2_k127_3149348_30 Type II secretion system (T2SS), protein J K02459 - - 0.0007138 50.0
TH2_k127_3149348_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 443.0
TH2_k127_3149348_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 427.0
TH2_k127_3149348_6 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 426.0
TH2_k127_3149348_7 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 374.0
TH2_k127_3149348_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 382.0
TH2_k127_3149348_9 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 309.0
TH2_k127_3338842_0 FtsX-like permease family K02004 - - 1.235e-319 997.0
TH2_k127_3338842_1 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 618.0
TH2_k127_3338842_10 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 393.0
TH2_k127_3338842_11 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 361.0
TH2_k127_3338842_12 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 366.0
TH2_k127_3338842_13 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 305.0
TH2_k127_3338842_14 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 327.0
TH2_k127_3338842_15 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 294.0
TH2_k127_3338842_16 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001761 278.0
TH2_k127_3338842_17 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000004105 267.0
TH2_k127_3338842_18 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000006043 258.0
TH2_k127_3338842_19 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002111 254.0
TH2_k127_3338842_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 587.0
TH2_k127_3338842_20 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000006608 233.0
TH2_k127_3338842_21 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000019 200.0
TH2_k127_3338842_22 - - - - 0.000000000000000000000000000000000000000000000000001231 194.0
TH2_k127_3338842_23 metal cluster binding - - - 0.000000000000000000000000000000000000000000000002326 180.0
TH2_k127_3338842_24 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000004093 161.0
TH2_k127_3338842_25 PFAM PHP domain - - - 0.0000000000000000000000000000000000000005345 158.0
TH2_k127_3338842_26 PFAM GCN5-related N-acetyltransferase K03824 - - 0.00000000000000000000000000000000001038 147.0
TH2_k127_3338842_27 SnoaL-like domain - - - 0.0000000000000000000000000000000001431 139.0
TH2_k127_3338842_28 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000001989 130.0
TH2_k127_3338842_29 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0000000000000000000001291 107.0
TH2_k127_3338842_3 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 535.0
TH2_k127_3338842_30 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000006266 101.0
TH2_k127_3338842_31 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000002106 92.0
TH2_k127_3338842_32 - - - - 0.0000000000000002557 84.0
TH2_k127_3338842_33 - - - - 0.00000000000000178 83.0
TH2_k127_3338842_35 Evidence 4 Homologs of previously reported genes of - - - 0.000000001607 62.0
TH2_k127_3338842_36 - - - - 0.000001553 52.0
TH2_k127_3338842_37 response regulator - - - 0.00001174 55.0
TH2_k127_3338842_4 Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 525.0
TH2_k127_3338842_5 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 519.0
TH2_k127_3338842_6 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 477.0
TH2_k127_3338842_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 477.0
TH2_k127_3338842_8 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 479.0
TH2_k127_3338842_9 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 445.0
TH2_k127_3358988_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1038.0
TH2_k127_3358988_1 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 416.0
TH2_k127_3358988_2 Surface antigen K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006191 259.0
TH2_k127_3358988_3 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0000000000000000000000000000000000115 137.0
TH2_k127_3361367_0 GTP-binding protein TypA K06207 - - 6.218e-208 659.0
TH2_k127_3361367_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 2.495e-207 661.0
TH2_k127_3361367_10 binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 406.0
TH2_k127_3361367_11 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 404.0
TH2_k127_3361367_12 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 396.0
TH2_k127_3361367_13 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 390.0
TH2_k127_3361367_14 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 374.0
TH2_k127_3361367_15 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 378.0
TH2_k127_3361367_16 Protein of unknown function DUF111 K06898,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 385.0
TH2_k127_3361367_17 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 363.0
TH2_k127_3361367_18 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 349.0
TH2_k127_3361367_19 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 345.0
TH2_k127_3361367_2 Major facilitator - - - 9.561e-205 643.0
TH2_k127_3361367_20 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 358.0
TH2_k127_3361367_21 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 320.0
TH2_k127_3361367_22 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 313.0
TH2_k127_3361367_23 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 308.0
TH2_k127_3361367_24 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 317.0
TH2_k127_3361367_25 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001405 280.0
TH2_k127_3361367_26 PFAM flavin reductase domain protein FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000001366 210.0
TH2_k127_3361367_27 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000002635 176.0
TH2_k127_3361367_28 radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000001084 168.0
TH2_k127_3361367_29 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000001446 153.0
TH2_k127_3361367_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.406e-202 637.0
TH2_k127_3361367_30 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000373 152.0
TH2_k127_3361367_31 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000001299 160.0
TH2_k127_3361367_32 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000002492 139.0
TH2_k127_3361367_33 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000002886 117.0
TH2_k127_3361367_34 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000000000008626 108.0
TH2_k127_3361367_35 - - - - 0.0000000000000000000007188 99.0
TH2_k127_3361367_36 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000004038 96.0
TH2_k127_3361367_37 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000007928 98.0
TH2_k127_3361367_38 - - - - 0.000000000000000002489 86.0
TH2_k127_3361367_39 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000003315 85.0
TH2_k127_3361367_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 603.0
TH2_k127_3361367_40 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000004533 64.0
TH2_k127_3361367_41 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000006923 60.0
TH2_k127_3361367_42 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000002735 61.0
TH2_k127_3361367_43 PFAM Class II aldolase K01628 - 4.1.2.17 0.0000002918 57.0
TH2_k127_3361367_44 PFAM Bacterial membrane protein YfhO - - - 0.000001994 61.0
TH2_k127_3361367_46 Evidence 5 No homology to any previously reported sequences - - - 0.0003376 52.0
TH2_k127_3361367_5 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 474.0
TH2_k127_3361367_6 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 476.0
TH2_k127_3361367_7 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 441.0
TH2_k127_3361367_8 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 419.0
TH2_k127_3361367_9 Sensor diguanylate cyclase, PAS domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 404.0
TH2_k127_3411737_0 General secretory system II, protein E domain protein K02652 - - 9.468e-218 707.0
TH2_k127_3411737_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 546.0
TH2_k127_3411737_10 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000008351 280.0
TH2_k127_3411737_11 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000209 283.0
TH2_k127_3411737_12 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000002598 217.0
TH2_k127_3411737_13 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000001301 214.0
TH2_k127_3411737_14 PFAM Isochorismatase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000008252 197.0
TH2_k127_3411737_15 pfam ammecr1 K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000001573 201.0
TH2_k127_3411737_16 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000002339 196.0
TH2_k127_3411737_17 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000004162 195.0
TH2_k127_3411737_18 Transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' - - - 0.000000000000000000000000000000000000000001094 163.0
TH2_k127_3411737_19 acyl-CoA dehydrogenase activity K06446 - - 0.000000000000000000000000000000003926 152.0
TH2_k127_3411737_2 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 456.0
TH2_k127_3411737_20 Type II secretory pathway pseudopilin - - - 0.000000000000000000000000000132 130.0
TH2_k127_3411737_21 Protein of unknown function (DUF1622) - - - 0.000000000000000000003052 98.0
TH2_k127_3411737_22 Large extracellular alpha-helical protein - - - 0.0000000000000002076 95.0
TH2_k127_3411737_23 methyltransferase activity - - - 0.000000000000001396 85.0
TH2_k127_3411737_25 - - - - 0.00000000000002207 85.0
TH2_k127_3411737_26 PEP-CTERM motif - - - 0.00000000000002581 82.0
TH2_k127_3411737_27 Protein of unknown function DUF116 - - - 0.0000000000006072 79.0
TH2_k127_3411737_28 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000006311 81.0
TH2_k127_3411737_3 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 432.0
TH2_k127_3411737_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 436.0
TH2_k127_3411737_5 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 415.0
TH2_k127_3411737_6 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 335.0
TH2_k127_3411737_7 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 308.0
TH2_k127_3411737_8 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 303.0
TH2_k127_3411737_9 Type II secretion system K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008503 280.0
TH2_k127_3446511_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 2.347e-220 700.0
TH2_k127_3446511_1 TonB dependent receptor K02014 - - 3.241e-203 653.0
TH2_k127_3446511_10 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 393.0
TH2_k127_3446511_11 sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 367.0
TH2_k127_3446511_12 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 364.0
TH2_k127_3446511_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 326.0
TH2_k127_3446511_14 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 308.0
TH2_k127_3446511_15 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 317.0
TH2_k127_3446511_16 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 291.0
TH2_k127_3446511_17 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001811 272.0
TH2_k127_3446511_18 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000183 274.0
TH2_k127_3446511_19 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000386 252.0
TH2_k127_3446511_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 496.0
TH2_k127_3446511_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005846 243.0
TH2_k127_3446511_21 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000000000000000000001117 218.0
TH2_k127_3446511_22 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000001343 212.0
TH2_k127_3446511_23 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000001261 216.0
TH2_k127_3446511_24 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000006699 195.0
TH2_k127_3446511_25 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000009305 197.0
TH2_k127_3446511_26 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000002294 193.0
TH2_k127_3446511_27 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001128 193.0
TH2_k127_3446511_28 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.000000000000000000000000000000000000000000000003597 184.0
TH2_k127_3446511_29 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000001493 185.0
TH2_k127_3446511_3 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 481.0
TH2_k127_3446511_30 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000002986 177.0
TH2_k127_3446511_31 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K13613 - - 0.0000000000000000000000000000000000000000000001553 175.0
TH2_k127_3446511_32 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000431 174.0
TH2_k127_3446511_33 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000001694 168.0
TH2_k127_3446511_34 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000000000000002723 160.0
TH2_k127_3446511_35 Could be involved in septation K06412 - - 0.0000000000000000000000000000000002359 134.0
TH2_k127_3446511_36 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000001843 141.0
TH2_k127_3446511_37 cheY-homologous receiver domain - - - 0.00000000000000000000000003667 118.0
TH2_k127_3446511_38 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000006706 113.0
TH2_k127_3446511_39 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000112 108.0
TH2_k127_3446511_4 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 442.0
TH2_k127_3446511_40 translation release factor activity - - - 0.000000000000000000000573 101.0
TH2_k127_3446511_41 Regulatory protein, FmdB family - - - 0.0000000000000000008123 89.0
TH2_k127_3446511_42 - - - - 0.000006483 55.0
TH2_k127_3446511_43 cheY-homologous receiver domain - - - 0.00002439 51.0
TH2_k127_3446511_44 PFAM Rhodanese domain protein - - - 0.00003245 54.0
TH2_k127_3446511_45 Cell envelope biogenesis protein TolA K03646 - - 0.0001064 53.0
TH2_k127_3446511_46 - - - - 0.0009159 48.0
TH2_k127_3446511_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 424.0
TH2_k127_3446511_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 446.0
TH2_k127_3446511_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 408.0
TH2_k127_3446511_8 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 406.0
TH2_k127_3446511_9 ABC transporter substrate binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 395.0
TH2_k127_3506521_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 1.411e-274 868.0
TH2_k127_3506521_1 PAS domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 473.0
TH2_k127_3506521_10 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000009449 195.0
TH2_k127_3506521_11 isomerase activity - - - 0.0000000000000000197 97.0
TH2_k127_3506521_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 395.0
TH2_k127_3506521_3 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 336.0
TH2_k127_3506521_4 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 342.0
TH2_k127_3506521_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 304.0
TH2_k127_3506521_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000259 282.0
TH2_k127_3506521_7 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000002037 265.0
TH2_k127_3506521_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000003939 259.0
TH2_k127_3506521_9 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007878 243.0
TH2_k127_3557360_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1143.0
TH2_k127_3557360_1 DNA polymerase A domain K02335 - 2.7.7.7 2.11e-308 970.0
TH2_k127_3557360_10 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 559.0
TH2_k127_3557360_11 phosphorelay signal transduction system K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 524.0
TH2_k127_3557360_12 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 533.0
TH2_k127_3557360_13 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 511.0
TH2_k127_3557360_14 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 455.0
TH2_k127_3557360_15 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 454.0
TH2_k127_3557360_16 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 442.0
TH2_k127_3557360_17 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 402.0
TH2_k127_3557360_18 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 379.0
TH2_k127_3557360_19 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 379.0
TH2_k127_3557360_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.846e-252 803.0
TH2_k127_3557360_20 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 376.0
TH2_k127_3557360_21 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009143 371.0
TH2_k127_3557360_22 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 378.0
TH2_k127_3557360_23 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 347.0
TH2_k127_3557360_24 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 346.0
TH2_k127_3557360_25 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 349.0
TH2_k127_3557360_26 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 353.0
TH2_k127_3557360_27 Putative Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 340.0
TH2_k127_3557360_28 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 323.0
TH2_k127_3557360_29 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 310.0
TH2_k127_3557360_3 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 9.759e-246 777.0
TH2_k127_3557360_30 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 305.0
TH2_k127_3557360_31 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 294.0
TH2_k127_3557360_32 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 287.0
TH2_k127_3557360_33 PFAM Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009191 291.0
TH2_k127_3557360_34 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006515 287.0
TH2_k127_3557360_35 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004516 280.0
TH2_k127_3557360_36 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006495 261.0
TH2_k127_3557360_37 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001324 267.0
TH2_k127_3557360_38 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000007824 261.0
TH2_k127_3557360_39 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001199 258.0
TH2_k127_3557360_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 2.85e-209 653.0
TH2_k127_3557360_40 -O-antigen K02847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003871 261.0
TH2_k127_3557360_41 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000654 248.0
TH2_k127_3557360_42 N-terminal domain of galactosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
TH2_k127_3557360_43 tRNA pseudouridylate synthase B C-terminal domain K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000002383 245.0
TH2_k127_3557360_44 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000002506 244.0
TH2_k127_3557360_45 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000008252 246.0
TH2_k127_3557360_46 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000481 219.0
TH2_k127_3557360_47 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000002472 205.0
TH2_k127_3557360_48 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000001504 224.0
TH2_k127_3557360_49 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000002361 194.0
TH2_k127_3557360_5 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 4.255e-202 639.0
TH2_k127_3557360_50 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000678 199.0
TH2_k127_3557360_51 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000072 190.0
TH2_k127_3557360_52 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000005826 179.0
TH2_k127_3557360_53 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000287 168.0
TH2_k127_3557360_54 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000345 149.0
TH2_k127_3557360_55 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000005005 146.0
TH2_k127_3557360_56 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000005128 139.0
TH2_k127_3557360_57 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000008583 141.0
TH2_k127_3557360_58 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000009555 133.0
TH2_k127_3557360_59 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000001926 122.0
TH2_k127_3557360_6 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 2.141e-201 645.0
TH2_k127_3557360_60 - - - - 0.000000000000000000000000000002156 126.0
TH2_k127_3557360_61 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000003017 124.0
TH2_k127_3557360_62 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000008555 126.0
TH2_k127_3557360_63 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000002801 113.0
TH2_k127_3557360_64 PFAM Smr protein MutS2 - - - 0.000000000000000000000000003293 120.0
TH2_k127_3557360_65 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.00000000000000000000000039 113.0
TH2_k127_3557360_66 Domain of unknown function (DUF1957) K16149 - 2.4.1.18 0.0000000000000000000000007705 117.0
TH2_k127_3557360_67 NifU-like domain - - - 0.000000000000000000000002061 113.0
TH2_k127_3557360_68 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000003709 85.0
TH2_k127_3557360_69 Cellulose 1,4-beta-cellobiosidase - - - 0.0000000000000008279 92.0
TH2_k127_3557360_7 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.188e-197 626.0
TH2_k127_3557360_70 TIGRFAM C-3',4' desaturase CrtD - - - 0.000000009318 67.0
TH2_k127_3557360_71 PFAM Late competence development protein ComFB K02241 - - 0.0000003758 55.0
TH2_k127_3557360_72 - - - - 0.000003436 55.0
TH2_k127_3557360_73 AsmA family K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.0001205 56.0
TH2_k127_3557360_74 unfolded protein binding K06142 - - 0.0002646 50.0
TH2_k127_3557360_75 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0007293 52.0
TH2_k127_3557360_8 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 586.0
TH2_k127_3557360_9 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 550.0
TH2_k127_3589258_0 NHL repeat - - - 0.00000000000000000546 100.0
TH2_k127_3589258_1 domain protein K13735,K20276 - - 0.000000000000004151 88.0
TH2_k127_3589258_2 cellulase activity K01727 - 4.2.2.1 0.0000000000001666 82.0
TH2_k127_3589258_3 domain, Protein - - - 0.00000000008534 76.0
TH2_k127_3589258_4 peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00003635 57.0
TH2_k127_3739709_0 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 556.0
TH2_k127_3739709_1 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000461 84.0
TH2_k127_3809326_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1063.0
TH2_k127_3809326_1 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 349.0
TH2_k127_3809326_10 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000002426 91.0
TH2_k127_3809326_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.000000000000006484 77.0
TH2_k127_3809326_12 Sporulation and spore germination - - - 0.000000000001162 76.0
TH2_k127_3809326_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 335.0
TH2_k127_3809326_3 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003128 303.0
TH2_k127_3809326_4 - K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000001354 229.0
TH2_k127_3809326_5 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000004042 213.0
TH2_k127_3809326_6 CutA1 divalent ion tolerance protein K01733,K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840 4.2.3.1 0.0000000000000000000000000001136 119.0
TH2_k127_3809326_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.00000000000000000000000009988 117.0
TH2_k127_3809326_8 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000001553 110.0
TH2_k127_3809326_9 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000002576 103.0
TH2_k127_3809331_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1271.0
TH2_k127_3809331_1 Fatty acid cis/trans isomerase (CTI) - - - 0.0 1253.0
TH2_k127_3809331_10 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 342.0
TH2_k127_3809331_11 COG2829 Outer membrane phospholipase A K01058 GO:0003674,GO:0003824,GO:0004620,GO:0004623,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005623,GO:0008970,GO:0009279,GO:0016020,GO:0016021,GO:0016298,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044462,GO:0044464,GO:0045203,GO:0046872,GO:0046983,GO:0052689,GO:0071944 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 302.0
TH2_k127_3809331_12 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 298.0
TH2_k127_3809331_13 ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007311 283.0
TH2_k127_3809331_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 249.0
TH2_k127_3809331_15 response regulator K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002188 258.0
TH2_k127_3809331_16 PPIC-type PPIASE domain - - - 0.000000000000000000000000000000000000000000000000000000000001456 222.0
TH2_k127_3809331_17 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000002206 206.0
TH2_k127_3809331_18 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000000004899 192.0
TH2_k127_3809331_19 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.0000000000000000000000000000000000000000000004823 172.0
TH2_k127_3809331_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1234.0
TH2_k127_3809331_20 Cysteine rich repeat - - - 0.000000000000000000000000000000000000000000003044 169.0
TH2_k127_3809331_21 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000004454 169.0
TH2_k127_3809331_22 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000002453 156.0
TH2_k127_3809331_23 Ion transport 2 domain protein - - - 0.0000000000000000000000000000003757 131.0
TH2_k127_3809331_24 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000211 118.0
TH2_k127_3809331_26 - - - - 0.00000000000000001381 92.0
TH2_k127_3809331_27 - - - - 0.00000000000000004963 89.0
TH2_k127_3809331_28 - - - - 0.0000000000000397 81.0
TH2_k127_3809331_29 META domain K09914 - - 0.0000000000004866 77.0
TH2_k127_3809331_3 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.386e-275 857.0
TH2_k127_3809331_30 - - - - 0.00001574 53.0
TH2_k127_3809331_31 - - - - 0.0001007 52.0
TH2_k127_3809331_4 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 1.603e-262 825.0
TH2_k127_3809331_5 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 1.039e-221 696.0
TH2_k127_3809331_6 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 7.925e-214 670.0
TH2_k127_3809331_7 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 526.0
TH2_k127_3809331_8 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 425.0
TH2_k127_3809331_9 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 387.0
TH2_k127_3821856_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 596.0
TH2_k127_3821856_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 353.0
TH2_k127_3821856_10 Domain of unknown function (DUF386) - - - 0.000000000000000000000000001068 118.0
TH2_k127_3821856_11 phosphorelay signal transduction system - - - 0.00000000000000000000000003387 113.0
TH2_k127_3821856_12 Membrane - - - 0.000000008965 65.0
TH2_k127_3821856_13 - - - - 0.00001308 52.0
TH2_k127_3821856_2 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 347.0
TH2_k127_3821856_3 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 340.0
TH2_k127_3821856_4 metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 304.0
TH2_k127_3821856_5 Predicted membrane protein (DUF2238) K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 291.0
TH2_k127_3821856_6 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001851 305.0
TH2_k127_3821856_7 membrane organization K20543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001081 274.0
TH2_k127_3821856_8 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000001067 217.0
TH2_k127_3821856_9 Homeodomain-like domain K07497 - - 0.00000000000000000000000000000000000009498 144.0
TH2_k127_3822927_0 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 544.0
TH2_k127_3822927_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 511.0
TH2_k127_3822927_10 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000005196 220.0
TH2_k127_3822927_11 Deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000808 205.0
TH2_k127_3822927_12 Glycosyl hydrolases family 6 K19668 - 3.2.1.91 0.0000000000000000000000000000000000000000000000000002213 208.0
TH2_k127_3822927_13 PFAM Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000001563 167.0
TH2_k127_3822927_14 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000001278 137.0
TH2_k127_3822927_15 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.00000000000000000000006215 103.0
TH2_k127_3822927_16 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000001738 97.0
TH2_k127_3822927_18 PEP-CTERM motif - - - 0.0001036 52.0
TH2_k127_3822927_19 Protein of unknown function (DUF1059) - - - 0.0004736 48.0
TH2_k127_3822927_2 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 483.0
TH2_k127_3822927_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 411.0
TH2_k127_3822927_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 372.0
TH2_k127_3822927_5 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 333.0
TH2_k127_3822927_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 339.0
TH2_k127_3822927_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 290.0
TH2_k127_3822927_8 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004276 281.0
TH2_k127_3822927_9 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000145 282.0
TH2_k127_38552_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1039.0
TH2_k127_38552_1 4Fe-4S dicluster domain - - - 7.748e-301 928.0
TH2_k127_38552_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 364.0
TH2_k127_38552_11 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 346.0
TH2_k127_38552_12 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 338.0
TH2_k127_38552_13 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 334.0
TH2_k127_38552_14 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 326.0
TH2_k127_38552_15 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 325.0
TH2_k127_38552_16 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 308.0
TH2_k127_38552_17 nitric oxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000002616 208.0
TH2_k127_38552_18 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000002686 194.0
TH2_k127_38552_19 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000000000000000000000000000000000001542 177.0
TH2_k127_38552_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.119e-264 828.0
TH2_k127_38552_20 COGs COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000001005 166.0
TH2_k127_38552_21 - - - - 0.000000000000000000000000000000000000000001375 161.0
TH2_k127_38552_22 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000001927 163.0
TH2_k127_38552_23 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000002035 143.0
TH2_k127_38552_24 Protein of unknown function (DUF2845) - - - 0.000000000000000000000000000000000004455 144.0
TH2_k127_38552_25 Fe-S cluster domain protein - - - 0.000000000000000000000000000001607 131.0
TH2_k127_38552_26 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000002332 110.0
TH2_k127_38552_27 PFAM sigma-54 factor interaction domain-containing protein, Propionate catabolism activator domain-containing protein - - - 0.0000000000000000000000002683 114.0
TH2_k127_38552_28 PFAM 4Fe-4S ferredoxin - - - 0.00000000000000001801 83.0
TH2_k127_38552_29 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000000000000002846 81.0
TH2_k127_38552_3 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 603.0
TH2_k127_38552_30 - - - - 0.000000000000001522 79.0
TH2_k127_38552_31 DsrE/DsrF-like family K07235 - - 0.000000000001931 72.0
TH2_k127_38552_32 Transduction Histidine Kinase K07711 - 2.7.13.3 0.00000000001419 76.0
TH2_k127_38552_33 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000497 70.0
TH2_k127_38552_35 Sigma-54 interaction domain K21405 - - 0.00002259 49.0
TH2_k127_38552_36 cheY-homologous receiver domain - - - 0.00003937 55.0
TH2_k127_38552_37 Transcriptional regulator - - - 0.00006612 46.0
TH2_k127_38552_38 sulfur relay protein TusB DsrH K07237 - - 0.00008658 49.0
TH2_k127_38552_39 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0002345 49.0
TH2_k127_38552_4 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 597.0
TH2_k127_38552_5 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 535.0
TH2_k127_38552_6 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 499.0
TH2_k127_38552_7 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 425.0
TH2_k127_38552_8 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 418.0
TH2_k127_38552_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 396.0
TH2_k127_405527_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.888e-213 681.0
TH2_k127_4148122_0 Bacterial protein of unknown function (DUF853) K06915 - - 9.595e-215 676.0
TH2_k127_4148122_1 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 2.366e-194 622.0
TH2_k127_4148122_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 441.0
TH2_k127_4148122_11 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 428.0
TH2_k127_4148122_12 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 433.0
TH2_k127_4148122_13 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 404.0
TH2_k127_4148122_14 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 356.0
TH2_k127_4148122_15 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 337.0
TH2_k127_4148122_16 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 316.0
TH2_k127_4148122_17 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 302.0
TH2_k127_4148122_18 ATPases associated with a variety of cellular activities K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 297.0
TH2_k127_4148122_19 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 288.0
TH2_k127_4148122_2 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 4.209e-194 620.0
TH2_k127_4148122_20 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001943 268.0
TH2_k127_4148122_21 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001019 283.0
TH2_k127_4148122_22 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002207 260.0
TH2_k127_4148122_23 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000588 236.0
TH2_k127_4148122_24 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000008668 229.0
TH2_k127_4148122_25 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005088 226.0
TH2_k127_4148122_26 Transglycosylase SLT domain K06381,K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000003966 247.0
TH2_k127_4148122_27 - - - - 0.000000000000000000000000000000000000000000000000000000000004151 224.0
TH2_k127_4148122_28 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000006466 208.0
TH2_k127_4148122_29 - - - - 0.00000000000000000000000000000000000000000000000000000001096 212.0
TH2_k127_4148122_3 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 567.0
TH2_k127_4148122_30 Fe-S iron-sulfur cluster assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000000000000000003729 199.0
TH2_k127_4148122_31 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000001233 199.0
TH2_k127_4148122_32 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000001796 193.0
TH2_k127_4148122_33 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000001177 187.0
TH2_k127_4148122_34 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000001124 174.0
TH2_k127_4148122_35 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000005807 168.0
TH2_k127_4148122_36 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000000000147 165.0
TH2_k127_4148122_37 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000004153 162.0
TH2_k127_4148122_39 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000009737 162.0
TH2_k127_4148122_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 556.0
TH2_k127_4148122_40 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000001204 146.0
TH2_k127_4148122_41 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000001392 146.0
TH2_k127_4148122_42 system, mannose fructose sorbose family, IID component K02796 - - 0.00000000000000000000000000000000001501 147.0
TH2_k127_4148122_43 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000003721 141.0
TH2_k127_4148122_44 - - - - 0.0000000000000000000000000000001125 134.0
TH2_k127_4148122_45 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000000000000001108 123.0
TH2_k127_4148122_46 PTS system fructose IIA component K02793,K02794 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0008645,GO:0008982,GO:0009401,GO:0009987,GO:0015144,GO:0015145,GO:0015149,GO:0015578,GO:0015749,GO:0015761,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0022870,GO:0031224,GO:0031226,GO:0034219,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046323,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098657,GO:0098704,GO:0098708,GO:0098739,GO:1904659 2.7.1.191 0.00000000000000000000000000001872 123.0
TH2_k127_4148122_47 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000001076 120.0
TH2_k127_4148122_48 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000103 113.0
TH2_k127_4148122_49 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000004301 114.0
TH2_k127_4148122_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 523.0
TH2_k127_4148122_50 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000002091 109.0
TH2_k127_4148122_51 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000373 108.0
TH2_k127_4148122_52 PFAM membrane protein of K08972 - - 0.00000000000000000000007858 103.0
TH2_k127_4148122_53 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000000004325 98.0
TH2_k127_4148122_54 - - - - 0.000000000000000000002753 95.0
TH2_k127_4148122_55 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000003443 95.0
TH2_k127_4148122_56 Phosphotransferase System K11189 - - 0.000000000000000000008421 104.0
TH2_k127_4148122_57 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000001826 93.0
TH2_k127_4148122_58 PTS system K02795 - - 0.0000000000000000009187 96.0
TH2_k127_4148122_59 PFAM Cobalt transport protein K02008 - - 0.000000000000000005973 94.0
TH2_k127_4148122_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 494.0
TH2_k127_4148122_60 PFAM 4Fe-4S ferredoxin - - - 0.000000000000001825 77.0
TH2_k127_4148122_61 Putative zinc- or iron-chelating domain K06940 - - 0.00000000001134 74.0
TH2_k127_4148122_62 - - - - 0.0000000005467 68.0
TH2_k127_4148122_63 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0000000006076 71.0
TH2_k127_4148122_67 NosL K19342 - - 0.000002971 55.0
TH2_k127_4148122_68 Histidine Phosphotransfer domain - - - 0.0003281 53.0
TH2_k127_4148122_7 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 484.0
TH2_k127_4148122_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 492.0
TH2_k127_4148122_9 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 490.0
TH2_k127_452687_0 DNA topoisomerase II activity K02469,K02621 GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 5.99.1.3 1.605e-219 704.0
TH2_k127_452687_1 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001447 297.0
TH2_k127_452687_11 PFAM Metallophosphoesterase K07098 - - 0.00000000004396 68.0
TH2_k127_452687_12 HD domain - - - 0.000000006179 64.0
TH2_k127_452687_13 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000006807 66.0
TH2_k127_452687_14 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.000006591 53.0
TH2_k127_452687_2 PFAM Phosphatidic acid phosphatase type 2 haloperoxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002814 261.0
TH2_k127_452687_3 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000000000000004847 206.0
TH2_k127_452687_4 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000001134 170.0
TH2_k127_452687_5 GYD domain - - - 0.000000000000000000000000000000000001793 140.0
TH2_k127_452687_6 HD domain - - - 0.000000000000000000000001453 106.0
TH2_k127_452687_7 Uncharacterised protein family UPF0047 - - - 0.00000000000000000173 85.0
TH2_k127_452687_8 phosphohydrolase - - - 0.000000000000000002798 92.0
TH2_k127_452687_9 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000001965 91.0
TH2_k127_4589142_0 Heat shock 70 kDa protein K04043 - - 1.023e-299 930.0
TH2_k127_4589142_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 6.475e-240 756.0
TH2_k127_4589142_10 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 385.0
TH2_k127_4589142_11 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 370.0
TH2_k127_4589142_12 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 341.0
TH2_k127_4589142_13 Beta-ketoacyl synthase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 333.0
TH2_k127_4589142_14 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 332.0
TH2_k127_4589142_15 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 316.0
TH2_k127_4589142_16 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 301.0
TH2_k127_4589142_17 HrcA protein C terminal domain K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 299.0
TH2_k127_4589142_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 310.0
TH2_k127_4589142_19 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 287.0
TH2_k127_4589142_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 6.594e-194 611.0
TH2_k127_4589142_20 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000003671 253.0
TH2_k127_4589142_21 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000001095 253.0
TH2_k127_4589142_22 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001013 244.0
TH2_k127_4589142_23 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000001357 239.0
TH2_k127_4589142_24 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.000000000000000000000000000000000000000000000000000000000000001697 235.0
TH2_k127_4589142_25 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000000000005653 222.0
TH2_k127_4589142_26 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000004895 211.0
TH2_k127_4589142_27 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000002486 220.0
TH2_k127_4589142_28 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000001222 194.0
TH2_k127_4589142_29 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000008236 190.0
TH2_k127_4589142_3 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 586.0
TH2_k127_4589142_30 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000000000001283 173.0
TH2_k127_4589142_31 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000003151 154.0
TH2_k127_4589142_32 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000248 127.0
TH2_k127_4589142_33 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000254 127.0
TH2_k127_4589142_34 Putative methyltransferase - - - 0.00000000000000000000000000005388 131.0
TH2_k127_4589142_35 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000003095 111.0
TH2_k127_4589142_36 part of a sulfur-relay system K11179 - - 0.000000000000000000000006484 107.0
TH2_k127_4589142_37 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000005113 88.0
TH2_k127_4589142_39 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000001675 61.0
TH2_k127_4589142_4 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 559.0
TH2_k127_4589142_41 radical SAM domain protein - - - 0.0001071 55.0
TH2_k127_4589142_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 544.0
TH2_k127_4589142_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 438.0
TH2_k127_4589142_7 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 441.0
TH2_k127_4589142_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 409.0
TH2_k127_4589142_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 408.0
TH2_k127_4590385_0 CBS domain containing protein K00974 - 2.7.7.72 3.189e-261 831.0
TH2_k127_4590385_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.261e-256 807.0
TH2_k127_4590385_10 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 557.0
TH2_k127_4590385_11 B3/4 domain K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 557.0
TH2_k127_4590385_12 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 536.0
TH2_k127_4590385_13 Ion transport 2 domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 505.0
TH2_k127_4590385_14 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 501.0
TH2_k127_4590385_15 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 503.0
TH2_k127_4590385_16 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 477.0
TH2_k127_4590385_17 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 451.0
TH2_k127_4590385_18 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 413.0
TH2_k127_4590385_19 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 399.0
TH2_k127_4590385_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 9.252e-226 716.0
TH2_k127_4590385_20 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 400.0
TH2_k127_4590385_21 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 391.0
TH2_k127_4590385_22 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 362.0
TH2_k127_4590385_23 TIGRFAM Na Pi-cotransporter II-related protein K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 375.0
TH2_k127_4590385_24 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 358.0
TH2_k127_4590385_25 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 355.0
TH2_k127_4590385_26 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 348.0
TH2_k127_4590385_27 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 333.0
TH2_k127_4590385_28 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 318.0
TH2_k127_4590385_29 integrase domain protein SAM domain protein K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 311.0
TH2_k127_4590385_3 General secretory system II, protein E domain protein K02454 - - 3.353e-218 694.0
TH2_k127_4590385_30 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 299.0
TH2_k127_4590385_31 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 287.0
TH2_k127_4590385_32 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004515 270.0
TH2_k127_4590385_33 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000181 254.0
TH2_k127_4590385_34 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004703 259.0
TH2_k127_4590385_35 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003642 252.0
TH2_k127_4590385_36 CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002346 257.0
TH2_k127_4590385_37 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000001925 239.0
TH2_k127_4590385_38 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000006337 239.0
TH2_k127_4590385_39 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000007453 237.0
TH2_k127_4590385_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.148e-211 666.0
TH2_k127_4590385_40 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000002646 235.0
TH2_k127_4590385_41 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000001332 207.0
TH2_k127_4590385_42 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000003283 199.0
TH2_k127_4590385_43 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000006522 214.0
TH2_k127_4590385_44 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000003543 194.0
TH2_k127_4590385_45 - - - - 0.00000000000000000000000000000000000000000000000000002392 196.0
TH2_k127_4590385_46 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000005637 196.0
TH2_k127_4590385_47 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000000000000000001485 203.0
TH2_k127_4590385_48 self proteolysis - - - 0.000000000000000000000000000000000000000000000000005078 193.0
TH2_k127_4590385_49 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000001807 187.0
TH2_k127_4590385_5 PFAM nickel-dependent hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 605.0
TH2_k127_4590385_50 OmpA family K02557 - - 0.00000000000000000000000000000000000000000000000001942 190.0
TH2_k127_4590385_51 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000002126 182.0
TH2_k127_4590385_52 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000002592 160.0
TH2_k127_4590385_53 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000275 169.0
TH2_k127_4590385_54 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000003401 135.0
TH2_k127_4590385_55 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000114 117.0
TH2_k127_4590385_57 PBS lyase HEAT-like repeat - - - 0.000000000000000001343 101.0
TH2_k127_4590385_58 domain protein K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000003431 79.0
TH2_k127_4590385_59 - - - - 0.0000000000000131 78.0
TH2_k127_4590385_6 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 627.0
TH2_k127_4590385_60 protein transport across the cell outer membrane K08084 - - 0.00000000000002488 79.0
TH2_k127_4590385_61 Sporulation related domain - - - 0.00000000001167 74.0
TH2_k127_4590385_62 protein transport across the cell outer membrane K08084 - - 0.00000000001457 71.0
TH2_k127_4590385_64 Ribosomal protein L35 K02916 - - 0.00000000003316 67.0
TH2_k127_4590385_65 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K04333,K20918 - - 0.0000000001783 70.0
TH2_k127_4590385_66 HEAT repeats - - - 0.000000007852 69.0
TH2_k127_4590385_67 - - - - 0.0000001514 57.0
TH2_k127_4590385_69 COG4967 Tfp pilus assembly protein PilV K02671 - - 0.00003245 53.0
TH2_k127_4590385_7 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 589.0
TH2_k127_4590385_8 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 578.0
TH2_k127_4590385_9 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 573.0
TH2_k127_4601978_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 472.0
TH2_k127_4601978_1 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 335.0
TH2_k127_4601978_10 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000001712 76.0
TH2_k127_4601978_11 peptidyl-tyrosine sulfation - - - 0.000000002622 68.0
TH2_k127_4601978_12 repeat-containing protein - - - 0.000000005677 66.0
TH2_k127_4601978_13 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000004451 57.0
TH2_k127_4601978_2 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 321.0
TH2_k127_4601978_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002284 269.0
TH2_k127_4601978_4 PFAM Stage II sporulation K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000004882 242.0
TH2_k127_4601978_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000003834 225.0
TH2_k127_4601978_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000006911 181.0
TH2_k127_4601978_7 RuvA, C-terminal domain K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000004374 173.0
TH2_k127_4601978_8 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000008277 130.0
TH2_k127_4601978_9 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000004408 80.0
TH2_k127_4605969_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 2.54e-241 759.0
TH2_k127_4605969_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.484e-211 664.0
TH2_k127_4605969_10 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000007517 181.0
TH2_k127_4605969_11 Thioesterase superfamily K02614 - - 0.000000000000000000000000000000000000000003251 160.0
TH2_k127_4605969_12 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000001572 85.0
TH2_k127_4605969_13 Tetratricopeptide repeat - - - 0.000003825 58.0
TH2_k127_4605969_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 482.0
TH2_k127_4605969_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007777 461.0
TH2_k127_4605969_4 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 446.0
TH2_k127_4605969_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 444.0
TH2_k127_4605969_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 429.0
TH2_k127_4605969_7 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 332.0
TH2_k127_4605969_8 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 317.0
TH2_k127_4605969_9 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000006136 212.0
TH2_k127_4655880_0 ergothioneine biosynthetic process K01919,K06048 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000004935 259.0
TH2_k127_4655880_1 Kelch motif - - - 0.00000000000000000000000000000000000000000001763 179.0
TH2_k127_4655880_2 Protein of unknown function (DUF1475) - - - 0.000000000000000000000000000000551 126.0
TH2_k127_4655880_3 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000001441 108.0
TH2_k127_4655880_4 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.0000000000000000000002212 100.0
TH2_k127_4655880_5 NADPH-dependent FMN reductase - - - 0.000000000000000002551 85.0
TH2_k127_4655880_6 - - - - 0.0001808 48.0
TH2_k127_4679569_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 476.0
TH2_k127_4679569_1 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001178 156.0
TH2_k127_4717105_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1705.0
TH2_k127_4717105_1 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 9.984e-194 628.0
TH2_k127_4717105_10 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.000000000000000000000004013 117.0
TH2_k127_4717105_11 PFAM Curli production assembly transport component CsgG - - - 0.000000000000000000000005344 118.0
TH2_k127_4717105_12 Hep Hag repeat protein - - - 0.000000000000000000004395 106.0
TH2_k127_4717105_13 Protein of unknown function (DUF2846) - - - 0.0000001062 60.0
TH2_k127_4717105_14 - - - - 0.0004683 53.0
TH2_k127_4717105_2 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 515.0
TH2_k127_4717105_3 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 503.0
TH2_k127_4717105_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 353.0
TH2_k127_4717105_5 pfam abc K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 312.0
TH2_k127_4717105_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001202 280.0
TH2_k127_4717105_7 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000001118 236.0
TH2_k127_4717105_8 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000103 189.0
TH2_k127_4717105_9 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000003736 181.0
TH2_k127_4728482_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1037.0
TH2_k127_4728482_1 Methyl-viologen-reducing hydrogenase, delta subunit K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.2e-321 997.0
TH2_k127_4728482_2 FAD dependent oxidoreductase K16885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 518.0
TH2_k127_4728482_3 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 345.0
TH2_k127_4728482_4 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007265 278.0
TH2_k127_4728482_5 FAD binding domain K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002088 252.0
TH2_k127_4728482_6 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000004426 186.0
TH2_k127_4728482_7 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00000000000000000000000000000000002595 140.0
TH2_k127_4728482_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000004626 106.0
TH2_k127_4804176_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 4.513e-245 773.0
TH2_k127_4804176_1 glycolate transport K14393 - - 2.686e-226 715.0
TH2_k127_4804176_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000007836 157.0
TH2_k127_4804176_3 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000002965 116.0
TH2_k127_4804176_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000229 48.0
TH2_k127_4879522_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000001241 126.0
TH2_k127_4879522_1 CHASE K02488,K21009 - 2.7.7.65 0.000000000000001057 79.0
TH2_k127_4879522_2 Protein tyrosine kinase - - - 0.0000002207 64.0
TH2_k127_4888558_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1118.0
TH2_k127_4888558_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 540.0
TH2_k127_4888558_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 363.0
TH2_k127_4888558_3 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 350.0
TH2_k127_4888558_4 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 328.0
TH2_k127_4888558_5 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002337 264.0
TH2_k127_4888558_6 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000002152 186.0
TH2_k127_4888558_7 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.00000000000000000008586 101.0
TH2_k127_4888558_8 OsmC-like protein K07397 - - 0.0000003604 57.0
TH2_k127_489622_0 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005482 277.0
TH2_k127_489622_1 ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002755 268.0
TH2_k127_489622_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000001515 95.0
TH2_k127_4918510_0 PFAM carboxyl transferase K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 3.492e-279 865.0
TH2_k127_4918510_1 Conserved carboxylase domain K01571,K01960,K03416 - 2.1.3.1,4.1.1.3,6.4.1.1 6.631e-270 833.0
TH2_k127_4918510_10 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001998 271.0
TH2_k127_4918510_11 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005087 280.0
TH2_k127_4918510_12 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000005124 222.0
TH2_k127_4918510_13 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.000000000000000000000000000000000000000005879 157.0
TH2_k127_4918510_14 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000001848 156.0
TH2_k127_4918510_15 Sigma-54 interaction domain K06714 - - 0.00000000000000000000000000000003187 132.0
TH2_k127_4918510_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000001316 118.0
TH2_k127_4918510_17 - - - - 0.0000000000000000000000000005474 118.0
TH2_k127_4918510_18 Protein of unknown function DUF134 - - - 0.000000000000000000000001901 106.0
TH2_k127_4918510_19 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000009343 105.0
TH2_k127_4918510_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 587.0
TH2_k127_4918510_20 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000002504 104.0
TH2_k127_4918510_21 - - - - 0.000000000002334 79.0
TH2_k127_4918510_23 - K06039,K07092 - - 0.0000001154 60.0
TH2_k127_4918510_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 583.0
TH2_k127_4918510_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 581.0
TH2_k127_4918510_5 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 460.0
TH2_k127_4918510_6 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 436.0
TH2_k127_4918510_7 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 374.0
TH2_k127_4918510_8 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 362.0
TH2_k127_4918510_9 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 314.0
TH2_k127_4929057_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1300.0
TH2_k127_4929057_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 3.662e-231 725.0
TH2_k127_4929057_10 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000002889 176.0
TH2_k127_4929057_11 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000000000000000000005754 159.0
TH2_k127_4929057_12 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000000000000000001848 156.0
TH2_k127_4929057_13 transcriptional regulator K01420 - - 0.000000000000000000000000000000000000004749 155.0
TH2_k127_4929057_14 PFAM Glutaredoxin K06191 - - 0.00000000000000000001993 95.0
TH2_k127_4929057_15 Malonate decarboxylase K13929 - 2.3.1.187 0.000000000000000002612 86.0
TH2_k127_4929057_16 Cytochrome c - - - 0.0000000000001659 74.0
TH2_k127_4929057_17 membrane transporter protein K07090 - - 0.000000000005951 72.0
TH2_k127_4929057_19 PFAM Fibronectin, type III domain - - - 0.0000000007983 71.0
TH2_k127_4929057_2 FAD binding domain K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 572.0
TH2_k127_4929057_20 phosphorelay signal transduction system K01768,K07315 GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 3.1.3.3,4.6.1.1 0.0001941 51.0
TH2_k127_4929057_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 411.0
TH2_k127_4929057_4 self proteolysis K01342,K20276,K20951,K20952 - 3.4.21.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 358.0
TH2_k127_4929057_5 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 318.0
TH2_k127_4929057_6 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 309.0
TH2_k127_4929057_7 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001583 285.0
TH2_k127_4929057_8 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000002655 229.0
TH2_k127_4929057_9 Secreted repeat of unknown function - - - 0.000000000000000000000000000000000000000000000007818 175.0
TH2_k127_4947611_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 3.573e-318 990.0
TH2_k127_4947611_1 ABC transporter K06020 - 3.6.3.25 1.536e-297 921.0
TH2_k127_4947611_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 317.0
TH2_k127_4947611_11 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 306.0
TH2_k127_4947611_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001963 295.0
TH2_k127_4947611_13 chlorophyll binding K16191,K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009585 309.0
TH2_k127_4947611_14 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002529 278.0
TH2_k127_4947611_15 Cytochrome b/b6/petB K03887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003875 273.0
TH2_k127_4947611_16 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005773 273.0
TH2_k127_4947611_17 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000005258 241.0
TH2_k127_4947611_18 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000001378 228.0
TH2_k127_4947611_19 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000002422 215.0
TH2_k127_4947611_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 5.628e-231 743.0
TH2_k127_4947611_20 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000003417 196.0
TH2_k127_4947611_21 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000002731 177.0
TH2_k127_4947611_22 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000009656 166.0
TH2_k127_4947611_23 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000546 141.0
TH2_k127_4947611_24 protein with SCP PR1 domains - - - 0.00000000000000000000000000000000163 135.0
TH2_k127_4947611_25 denitrification pathway - - - 0.000000000000000000000000000000001633 136.0
TH2_k127_4947611_26 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000009347 121.0
TH2_k127_4947611_27 Sulphur transport K07112 - - 0.0000000000000000000000002327 111.0
TH2_k127_4947611_28 cheY-homologous receiver domain - - - 0.000000000000001177 86.0
TH2_k127_4947611_29 Cytochrome b(C-terminal)/b6/petD K03888 - - 0.00000000000001643 85.0
TH2_k127_4947611_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 605.0
TH2_k127_4947611_30 amine dehydrogenase activity - - - 0.00000000000004288 86.0
TH2_k127_4947611_31 PFAM PKD domain containing protein - - - 0.0000000000003977 83.0
TH2_k127_4947611_32 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.000000000002813 79.0
TH2_k127_4947611_33 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000002027 61.0
TH2_k127_4947611_34 cellulase activity - - - 0.00000002521 64.0
TH2_k127_4947611_35 SurA N-terminal domain - - - 0.0000001769 61.0
TH2_k127_4947611_36 deoxyhypusine monooxygenase activity - - - 0.000000346 63.0
TH2_k127_4947611_37 - - - - 0.0000733 53.0
TH2_k127_4947611_38 Tetratricopeptide repeat - - - 0.0006232 49.0
TH2_k127_4947611_4 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 485.0
TH2_k127_4947611_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 477.0
TH2_k127_4947611_6 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 396.0
TH2_k127_4947611_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 384.0
TH2_k127_4947611_8 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 366.0
TH2_k127_4947611_9 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 319.0
TH2_k127_495805_0 BadF BadG BcrA BcrD - - - 5.01e-217 691.0
TH2_k127_495805_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 376.0
TH2_k127_495805_2 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000734 273.0
TH2_k127_495805_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009672 274.0
TH2_k127_495805_4 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000129 190.0
TH2_k127_495805_5 phosphorelay signal transduction system K19622 - - 0.000000000000009071 79.0
TH2_k127_495805_6 - - - - 0.000003217 55.0
TH2_k127_4978996_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 404.0
TH2_k127_4978996_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000005626 54.0
TH2_k127_5277234_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1157.0
TH2_k127_5277234_1 Conserved carboxylase domain K01958 - 6.4.1.1 0.0 1070.0
TH2_k127_5277234_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 369.0
TH2_k127_5277234_11 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 359.0
TH2_k127_5277234_12 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 355.0
TH2_k127_5277234_13 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 356.0
TH2_k127_5277234_14 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 315.0
TH2_k127_5277234_15 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001819 282.0
TH2_k127_5277234_16 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008686 272.0
TH2_k127_5277234_17 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009581 245.0
TH2_k127_5277234_18 diguanylate cyclase - - - 0.00000000000000000000000000000000000000001257 169.0
TH2_k127_5277234_19 PFAM regulatory protein, MerR K13640 - - 0.000000000000000000000000000000007978 130.0
TH2_k127_5277234_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.9e-315 973.0
TH2_k127_5277234_20 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000001243 117.0
TH2_k127_5277234_21 deoxyhypusine monooxygenase activity - - - 0.000000000000000000001759 103.0
TH2_k127_5277234_22 Pilus assembly protein, PilP K02665 - - 0.000000000000000000007325 99.0
TH2_k127_5277234_23 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000009516 96.0
TH2_k127_5277234_24 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K13640,K18997 - - 0.0000000000000001272 81.0
TH2_k127_5277234_3 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 3.082e-261 820.0
TH2_k127_5277234_4 Pfam:CPSase_L_chain - - - 6.865e-241 756.0
TH2_k127_5277234_5 DNA polymerase K02347 - - 2.516e-219 694.0
TH2_k127_5277234_6 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 565.0
TH2_k127_5277234_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 451.0
TH2_k127_5277234_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 425.0
TH2_k127_5277234_9 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 395.0
TH2_k127_5621057_0 Large extracellular alpha-helical protein K06894 - - 0.0 2122.0
TH2_k127_5621057_1 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1531.0
TH2_k127_5621057_10 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 570.0
TH2_k127_5621057_100 Thioredoxin domain - - - 0.00000000000000000005928 96.0
TH2_k127_5621057_102 deoxyhypusine monooxygenase activity K05386 - - 0.00000000000000004041 87.0
TH2_k127_5621057_104 PFAM Heavy metal transport detoxification protein K07213 - - 0.0000000000000009663 79.0
TH2_k127_5621057_105 - - - - 0.000000000000002021 85.0
TH2_k127_5621057_106 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000002893 80.0
TH2_k127_5621057_107 extracellular matrix structural constituent - - - 0.00000000000005703 85.0
TH2_k127_5621057_108 FliG middle domain K02410 - - 0.0000000000001196 83.0
TH2_k127_5621057_109 nucleic acid-binding protein contains PIN domain - - - 0.000000000003965 72.0
TH2_k127_5621057_11 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 556.0
TH2_k127_5621057_110 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000004459 72.0
TH2_k127_5621057_112 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.00000000002762 68.0
TH2_k127_5621057_113 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000004836 67.0
TH2_k127_5621057_114 Cupin 2, conserved barrel domain protein - - - 0.0000000005256 64.0
TH2_k127_5621057_115 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.0000002101 55.0
TH2_k127_5621057_116 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000004367 57.0
TH2_k127_5621057_117 - - - - 0.0000005431 61.0
TH2_k127_5621057_119 oligopeptide transporter - - - 0.00001507 49.0
TH2_k127_5621057_12 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 537.0
TH2_k127_5621057_120 Tetratricopeptide repeat - - - 0.00001677 57.0
TH2_k127_5621057_121 Antitoxin Phd_YefM, type II toxin-antitoxin system K19159 - - 0.00001962 50.0
TH2_k127_5621057_122 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00001996 51.0
TH2_k127_5621057_123 HEAT repeat - - - 0.00005391 56.0
TH2_k127_5621057_124 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0001062 53.0
TH2_k127_5621057_125 Belongs to the HesB IscA family K13628 - - 0.0009593 44.0
TH2_k127_5621057_13 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 537.0
TH2_k127_5621057_14 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 534.0
TH2_k127_5621057_15 response regulator K02481,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 519.0
TH2_k127_5621057_16 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 512.0
TH2_k127_5621057_17 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 512.0
TH2_k127_5621057_18 hydroxypyruvate reductase K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 479.0
TH2_k127_5621057_19 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 467.0
TH2_k127_5621057_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.206e-314 976.0
TH2_k127_5621057_20 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 466.0
TH2_k127_5621057_21 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 469.0
TH2_k127_5621057_22 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 445.0
TH2_k127_5621057_23 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 454.0
TH2_k127_5621057_24 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 447.0
TH2_k127_5621057_25 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 433.0
TH2_k127_5621057_26 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 421.0
TH2_k127_5621057_27 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 427.0
TH2_k127_5621057_28 N-6 DNA Methylase K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 408.0
TH2_k127_5621057_29 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 400.0
TH2_k127_5621057_3 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 5.466e-253 793.0
TH2_k127_5621057_30 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 398.0
TH2_k127_5621057_31 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 392.0
TH2_k127_5621057_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 400.0
TH2_k127_5621057_33 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 368.0
TH2_k127_5621057_34 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 362.0
TH2_k127_5621057_35 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 347.0
TH2_k127_5621057_36 Uncharacterized protein family (UPF0051) K07033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 344.0
TH2_k127_5621057_37 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 358.0
TH2_k127_5621057_38 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 342.0
TH2_k127_5621057_39 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 331.0
TH2_k127_5621057_4 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 1.661e-247 778.0
TH2_k127_5621057_40 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 336.0
TH2_k127_5621057_41 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 323.0
TH2_k127_5621057_42 Domains HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 326.0
TH2_k127_5621057_43 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 323.0
TH2_k127_5621057_44 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 299.0
TH2_k127_5621057_45 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 301.0
TH2_k127_5621057_46 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 293.0
TH2_k127_5621057_47 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 287.0
TH2_k127_5621057_48 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001518 285.0
TH2_k127_5621057_49 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002306 286.0
TH2_k127_5621057_5 SMART Elongator protein 3 MiaB NifB - - - 4.862e-231 724.0
TH2_k127_5621057_50 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002382 277.0
TH2_k127_5621057_51 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000002066 264.0
TH2_k127_5621057_52 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000475 270.0
TH2_k127_5621057_53 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007274 254.0
TH2_k127_5621057_54 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000005221 240.0
TH2_k127_5621057_55 Cytidylate kinase K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000005591 238.0
TH2_k127_5621057_56 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000007146 239.0
TH2_k127_5621057_57 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000005802 233.0
TH2_k127_5621057_58 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000003527 241.0
TH2_k127_5621057_59 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000001359 232.0
TH2_k127_5621057_6 Uncharacterised protein family (UPF0182) K09118 - - 4.948e-217 681.0
TH2_k127_5621057_60 RecF/RecN/SMC N terminal domain K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000001556 235.0
TH2_k127_5621057_61 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007472 232.0
TH2_k127_5621057_62 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000007627 229.0
TH2_k127_5621057_63 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000003784 228.0
TH2_k127_5621057_64 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000004277 222.0
TH2_k127_5621057_65 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000005546 206.0
TH2_k127_5621057_66 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000001286 213.0
TH2_k127_5621057_67 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000000002099 201.0
TH2_k127_5621057_68 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000007617 198.0
TH2_k127_5621057_69 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000001557 198.0
TH2_k127_5621057_7 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 2.646e-215 688.0
TH2_k127_5621057_70 Putative Fe-S cluster - - - 0.0000000000000000000000000000000000000000000000000000332 192.0
TH2_k127_5621057_71 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000002493 182.0
TH2_k127_5621057_72 PFAM MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000000000000000001967 179.0
TH2_k127_5621057_73 low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000002536 181.0
TH2_k127_5621057_74 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000001135 171.0
TH2_k127_5621057_75 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000002506 162.0
TH2_k127_5621057_76 diguanylate cyclase - - - 0.000000000000000000000000000000000000000003959 174.0
TH2_k127_5621057_77 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000007089 172.0
TH2_k127_5621057_78 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000007016 153.0
TH2_k127_5621057_79 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000002843 141.0
TH2_k127_5621057_8 Sigma-54 interaction domain - - - 2.281e-211 666.0
TH2_k127_5621057_80 cytochrome complex assembly - - - 0.00000000000000000000000000000000006789 143.0
TH2_k127_5621057_81 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000001572 144.0
TH2_k127_5621057_82 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000001908 144.0
TH2_k127_5621057_83 PFAM OmpA K02557 - - 0.000000000000000000000000000000009484 136.0
TH2_k127_5621057_84 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000001964 133.0
TH2_k127_5621057_85 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000001235 123.0
TH2_k127_5621057_86 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000001063 130.0
TH2_k127_5621057_87 Domain of unknown function (DUF4253) - - - 0.0000000000000000000000000000248 128.0
TH2_k127_5621057_88 - - - - 0.00000000000000000000000000006955 119.0
TH2_k127_5621057_89 isopentenyl-diphosphate delta-isomerase activity - - - 0.00000000000000000000000000007437 124.0
TH2_k127_5621057_9 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.109e-201 642.0
TH2_k127_5621057_90 transmembrane transport - - - 0.00000000000000000000000000009234 126.0
TH2_k127_5621057_91 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000000002171 124.0
TH2_k127_5621057_92 Glutathione peroxidase - - - 0.00000000000000000000000003634 115.0
TH2_k127_5621057_93 PFAM N-6 DNA methylase K03427 - 2.1.1.72 0.00000000000000000000000004349 115.0
TH2_k127_5621057_94 - - - - 0.0000000000000000000000001758 119.0
TH2_k127_5621057_95 PFAM NHL repeat containing protein - - - 0.000000000000000000000003741 114.0
TH2_k127_5621057_96 - - - - 0.0000000000000000000002561 100.0
TH2_k127_5621057_97 cell redox homeostasis K02199,K03671 - - 0.000000000000000000002215 101.0
TH2_k127_5621057_98 metalloendopeptidase activity K03799 - - 0.000000000000000000005914 104.0
TH2_k127_5621057_99 cytochrome c biogenesis protein - - - 0.000000000000000000006768 104.0
TH2_k127_5695787_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 499.0
TH2_k127_5695787_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 485.0
TH2_k127_5695787_10 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 303.0
TH2_k127_5695787_11 esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 299.0
TH2_k127_5695787_12 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000006843 190.0
TH2_k127_5695787_13 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000005242 179.0
TH2_k127_5695787_14 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000009164 121.0
TH2_k127_5695787_15 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000003063 135.0
TH2_k127_5695787_16 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000001483 88.0
TH2_k127_5695787_17 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000004164 80.0
TH2_k127_5695787_19 - - - - 0.000000001267 68.0
TH2_k127_5695787_2 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 471.0
TH2_k127_5695787_21 Cysteine-rich secretory protein family - - - 0.00007865 48.0
TH2_k127_5695787_22 repeat-containing protein - - - 0.0009976 49.0
TH2_k127_5695787_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 433.0
TH2_k127_5695787_4 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K01008,K04487 - 2.7.9.3,2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 411.0
TH2_k127_5695787_5 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 402.0
TH2_k127_5695787_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 391.0
TH2_k127_5695787_7 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 373.0
TH2_k127_5695787_8 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 353.0
TH2_k127_5695787_9 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 348.0
TH2_k127_5750933_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 454.0
TH2_k127_5750933_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 406.0
TH2_k127_5750933_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 371.0
TH2_k127_5750933_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 351.0
TH2_k127_5777158_0 PFAM Aldo keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006957 266.0
TH2_k127_5777158_1 PFAM flavin reductase domain protein FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001543 226.0
TH2_k127_5777158_2 Kelch motif - - - 0.00000000000000000000000000000000000000005907 167.0
TH2_k127_5777158_3 SnoaL-like domain - - - 0.00000000000000000000000000000000000004813 147.0
TH2_k127_5794542_0 Aminotransferase class I and II K14261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 599.0
TH2_k127_5794542_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001492 273.0
TH2_k127_5860557_0 phosphorelay sensor kinase activity K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 385.0
TH2_k127_5860557_1 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 370.0
TH2_k127_5860557_2 Sigma-54 dependent response regulator K07714 - - 0.0003276 44.0
TH2_k127_5973494_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 1.364e-297 924.0
TH2_k127_5973494_1 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 2.16e-240 762.0
TH2_k127_5973494_10 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 352.0
TH2_k127_5973494_11 belongs to the CobB CobQ family K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 354.0
TH2_k127_5973494_12 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 348.0
TH2_k127_5973494_13 TIGRFAM phenazine biosynthesis protein PhzF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 333.0
TH2_k127_5973494_14 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 301.0
TH2_k127_5973494_15 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 297.0
TH2_k127_5973494_16 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001312 276.0
TH2_k127_5973494_17 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000001809 219.0
TH2_k127_5973494_18 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000005172 209.0
TH2_k127_5973494_19 Ribosomal protein L13 K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001261 198.0
TH2_k127_5973494_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 478.0
TH2_k127_5973494_20 DeoC/LacD family aldolase - - - 0.0000000000000000000000000000000000000000000000000167 187.0
TH2_k127_5973494_21 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000007111 177.0
TH2_k127_5973494_22 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000002534 150.0
TH2_k127_5973494_23 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000819 139.0
TH2_k127_5973494_26 denitrification pathway - - - 0.000000000000000000000000984 111.0
TH2_k127_5973494_27 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000003234 119.0
TH2_k127_5973494_28 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000005411 104.0
TH2_k127_5973494_29 Peptidase_C39 like family - - - 0.0000000000000000000229 103.0
TH2_k127_5973494_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 461.0
TH2_k127_5973494_30 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000002356 83.0
TH2_k127_5973494_31 - - - - 0.0000000000001811 75.0
TH2_k127_5973494_32 - - - - 0.0000000000003048 77.0
TH2_k127_5973494_33 cellulase activity - - - 0.000000000000393 83.0
TH2_k127_5973494_34 Protein of unknown function (DUF2934) - - - 0.000000001809 63.0
TH2_k127_5973494_37 PFAM FecR protein - - - 0.000003232 58.0
TH2_k127_5973494_39 Protein of unknown function (DUF560) - - - 0.00001358 57.0
TH2_k127_5973494_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 479.0
TH2_k127_5973494_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 419.0
TH2_k127_5973494_6 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 387.0
TH2_k127_5973494_7 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 384.0
TH2_k127_5973494_8 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 380.0
TH2_k127_5973494_9 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 378.0
TH2_k127_5983978_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.371e-281 882.0
TH2_k127_5983978_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 5.116e-200 632.0
TH2_k127_5983978_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002069 259.0
TH2_k127_5983978_11 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004986 264.0
TH2_k127_5983978_12 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000001922 214.0
TH2_k127_5983978_13 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000005736 213.0
TH2_k127_5983978_2 Pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 501.0
TH2_k127_5983978_3 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 374.0
TH2_k127_5983978_4 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 377.0
TH2_k127_5983978_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 351.0
TH2_k127_5983978_6 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 350.0
TH2_k127_5983978_7 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 311.0
TH2_k127_5983978_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001067 278.0
TH2_k127_5983978_9 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001541 282.0
TH2_k127_6151462_0 COG0058 Glucan phosphorylase - - - 2.647e-251 786.0
TH2_k127_6151462_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 613.0
TH2_k127_6151462_10 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 393.0
TH2_k127_6151462_11 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 366.0
TH2_k127_6151462_12 Protein of unknown function (DUF401) K09133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 326.0
TH2_k127_6151462_13 PFAM ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 314.0
TH2_k127_6151462_14 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 302.0
TH2_k127_6151462_15 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009343 284.0
TH2_k127_6151462_16 self proteolysis K01342,K20276,K20951,K20952 - 3.4.21.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000004965 278.0
TH2_k127_6151462_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002881 260.0
TH2_k127_6151462_18 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001031 258.0
TH2_k127_6151462_19 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000002711 227.0
TH2_k127_6151462_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 598.0
TH2_k127_6151462_20 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000002609 214.0
TH2_k127_6151462_21 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000001176 224.0
TH2_k127_6151462_22 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000003867 203.0
TH2_k127_6151462_23 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000001129 198.0
TH2_k127_6151462_24 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000006082 193.0
TH2_k127_6151462_25 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000002337 188.0
TH2_k127_6151462_26 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000008919 172.0
TH2_k127_6151462_27 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000303 164.0
TH2_k127_6151462_28 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000002063 163.0
TH2_k127_6151462_29 Molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.0000000000000000000000000000000000001541 148.0
TH2_k127_6151462_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 587.0
TH2_k127_6151462_30 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000005617 138.0
TH2_k127_6151462_31 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000004987 117.0
TH2_k127_6151462_32 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000008333 119.0
TH2_k127_6151462_33 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000001709 117.0
TH2_k127_6151462_34 Zincin-like metallopeptidase - - - 0.000000000000000000000005684 105.0
TH2_k127_6151462_35 antisigma factor binding K04749 - - 0.000000000000000001031 90.0
TH2_k127_6151462_36 energy transducer activity K03832 - - 0.000000000000000002378 95.0
TH2_k127_6151462_37 Putative zinc- or iron-chelating domain - - - 0.00000000000000001536 91.0
TH2_k127_6151462_38 Protein of unknown function (DUF507) - - - 0.000000000000001015 81.0
TH2_k127_6151462_39 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.000000000000003525 82.0
TH2_k127_6151462_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 540.0
TH2_k127_6151462_40 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000000008522 78.0
TH2_k127_6151462_41 MlaD protein K02067 - - 0.0000000000002157 81.0
TH2_k127_6151462_42 Protein of unknown function (DUF507) - - - 0.0000000001896 71.0
TH2_k127_6151462_43 Endoglucanase K01179 - 3.2.1.4 0.00000003648 66.0
TH2_k127_6151462_44 Predicted membrane protein (DUF2232) K16785,K16786,K16787 - - 0.0000002185 62.0
TH2_k127_6151462_45 Putative zinc-finger - - - 0.000003269 57.0
TH2_k127_6151462_46 - - - - 0.0002024 51.0
TH2_k127_6151462_5 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 508.0
TH2_k127_6151462_6 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 469.0
TH2_k127_6151462_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 433.0
TH2_k127_6151462_8 PFAM 4Fe-4S K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 408.0
TH2_k127_6151462_9 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 413.0
TH2_k127_6160260_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1471.0
TH2_k127_6160260_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1182.0
TH2_k127_6160260_10 Alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 450.0
TH2_k127_6160260_11 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 439.0
TH2_k127_6160260_12 Two component signalling adaptor domain K02487,K06596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 446.0
TH2_k127_6160260_13 Alpha/beta hydrolase family K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 411.0
TH2_k127_6160260_14 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 405.0
TH2_k127_6160260_15 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 379.0
TH2_k127_6160260_16 cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 374.0
TH2_k127_6160260_17 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 385.0
TH2_k127_6160260_18 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 357.0
TH2_k127_6160260_19 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 352.0
TH2_k127_6160260_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1070.0
TH2_k127_6160260_20 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 347.0
TH2_k127_6160260_21 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 347.0
TH2_k127_6160260_22 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 337.0
TH2_k127_6160260_23 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 319.0
TH2_k127_6160260_24 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 316.0
TH2_k127_6160260_25 phosphorelay signal transduction system K02535,K13599,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 322.0
TH2_k127_6160260_26 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 320.0
TH2_k127_6160260_27 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 308.0
TH2_k127_6160260_28 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 310.0
TH2_k127_6160260_29 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 322.0
TH2_k127_6160260_3 Aconitase family (aconitate hydratase) - - - 6.012e-277 865.0
TH2_k127_6160260_30 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 308.0
TH2_k127_6160260_31 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 302.0
TH2_k127_6160260_32 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 293.0
TH2_k127_6160260_33 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 312.0
TH2_k127_6160260_34 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 295.0
TH2_k127_6160260_35 Pfam:Arch_ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 288.0
TH2_k127_6160260_36 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001714 281.0
TH2_k127_6160260_37 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001842 301.0
TH2_k127_6160260_38 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001525 264.0
TH2_k127_6160260_39 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000001036 245.0
TH2_k127_6160260_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 5.131e-216 686.0
TH2_k127_6160260_40 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000001077 242.0
TH2_k127_6160260_41 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000158 228.0
TH2_k127_6160260_42 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000005069 223.0
TH2_k127_6160260_43 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000706 229.0
TH2_k127_6160260_44 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000259 218.0
TH2_k127_6160260_45 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000009331 225.0
TH2_k127_6160260_46 anaerobic electron transport chain - GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0019645,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000262 229.0
TH2_k127_6160260_47 response regulator K02658 - - 0.000000000000000000000000000000000000000000000000000000002249 216.0
TH2_k127_6160260_48 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000006489 180.0
TH2_k127_6160260_49 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis - - - 0.000000000000000000000000000000000000000000000001239 179.0
TH2_k127_6160260_5 PFAM magnesium chelatase ChlI subunit K07391 - - 4.882e-206 654.0
TH2_k127_6160260_50 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000008989 184.0
TH2_k127_6160260_51 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000001165 172.0
TH2_k127_6160260_52 Twitching motility two-component system response regulator PilH K02658 - - 0.0000000000000000000000000000000000000000003724 160.0
TH2_k127_6160260_53 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000002632 152.0
TH2_k127_6160260_54 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000004511 152.0
TH2_k127_6160260_55 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000002598 148.0
TH2_k127_6160260_56 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000001725 144.0
TH2_k127_6160260_57 Universal stress protein family - - - 0.0000000000000000000000000000000000002891 147.0
TH2_k127_6160260_58 Smr domain - - - 0.000000000000000000000000000000000004357 148.0
TH2_k127_6160260_59 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000001588 140.0
TH2_k127_6160260_6 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009002 613.0
TH2_k127_6160260_60 PFAM response regulator receiver - - - 0.0000000000000000000000000000000002234 136.0
TH2_k127_6160260_61 - - - - 0.00000000000000000000000000000009284 143.0
TH2_k127_6160260_62 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000000000000000000000004992 130.0
TH2_k127_6160260_63 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000000000000000003149 135.0
TH2_k127_6160260_64 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000004114 138.0
TH2_k127_6160260_65 anaerobic respiration - - - 0.0000000000000000000000000004312 125.0
TH2_k127_6160260_66 response regulator - - - 0.00000000000000000000000002704 124.0
TH2_k127_6160260_67 Cysteine-rich small domain K07162 - - 0.00000000000000000000003289 102.0
TH2_k127_6160260_68 PFAM CheW domain protein K03408 - - 0.00000000000000000000006388 109.0
TH2_k127_6160260_69 - - - - 0.00000000000000000000009496 108.0
TH2_k127_6160260_7 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 578.0
TH2_k127_6160260_70 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000004335 105.0
TH2_k127_6160260_71 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000008351 90.0
TH2_k127_6160260_72 PFAM CheW domain protein K03408 - - 0.0000000000000000826 87.0
TH2_k127_6160260_73 Serine Threonine protein kinase K08738 - - 0.000000000000003683 89.0
TH2_k127_6160260_74 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191 - - 0.000000000001678 69.0
TH2_k127_6160260_75 Restriction endonuclease K07448 - - 0.0000000003779 60.0
TH2_k127_6160260_76 Protein of unknown function (DUF1566) - - - 0.0000000006024 72.0
TH2_k127_6160260_78 Two component signalling adaptor domain K03408 - - 0.000008682 53.0
TH2_k127_6160260_79 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) K01183,K19303 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009254,GO:0016787,GO:0019538,GO:0030203,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901564 3.2.1.14 0.00002948 57.0
TH2_k127_6160260_8 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 542.0
TH2_k127_6160260_80 PFAM CheW domain protein K03408 - - 0.0001077 53.0
TH2_k127_6160260_9 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 512.0
TH2_k127_6325262_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1191.0
TH2_k127_6325262_1 transporter antisigma-factor antagonist STAS K03321 - - 2.272e-217 692.0
TH2_k127_6325262_10 spectrin binding K15502,K15503,K16717 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0070013 - 0.0000000000000000000000072 118.0
TH2_k127_6325262_11 PFAM glycoside hydrolase family 13 domain protein - - - 0.0000000000000000079 87.0
TH2_k127_6325262_12 spectrin binding - - - 0.00000000007692 76.0
TH2_k127_6325262_13 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000000003743 64.0
TH2_k127_6325262_2 nitric oxide dioxygenase activity K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 495.0
TH2_k127_6325262_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001083 261.0
TH2_k127_6325262_4 - - - - 0.0000000000000000000000000000000000000000000000000000000003205 214.0
TH2_k127_6325262_5 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000002509 198.0
TH2_k127_6325262_6 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000001967 143.0
TH2_k127_6325262_7 Methyltransferase domain - - - 0.000000000000000000000000000000001393 141.0
TH2_k127_6325262_8 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.000000000000000000000000000000002523 138.0
TH2_k127_6325262_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000007277 129.0
TH2_k127_6447828_0 Cytochrome c554 and c-prime - - - 1.454e-207 655.0
TH2_k127_6447828_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 611.0
TH2_k127_6447828_10 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000000000000000000000000003836 184.0
TH2_k127_6447828_11 - K18829 - - 0.000000000000000000000000000003656 120.0
TH2_k127_6447828_12 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000001504 117.0
TH2_k127_6447828_13 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000008724 104.0
TH2_k127_6447828_15 S4 domain K14761 - - 0.0000000000000000134 84.0
TH2_k127_6447828_16 Transposase for insertion sequence element - - - 0.0000000000000005197 82.0
TH2_k127_6447828_17 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000001701 77.0
TH2_k127_6447828_18 - - - - 0.0000000000007919 71.0
TH2_k127_6447828_2 protein involved in outer membrane biogenesis K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 501.0
TH2_k127_6447828_20 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000001143 66.0
TH2_k127_6447828_21 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.000000000134 66.0
TH2_k127_6447828_22 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000001645 62.0
TH2_k127_6447828_23 regulator of chromosome condensation, RCC1 - - - 0.0001084 55.0
TH2_k127_6447828_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 470.0
TH2_k127_6447828_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 355.0
TH2_k127_6447828_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 301.0
TH2_k127_6447828_6 RNA pseudouridylate synthase K06175 - 5.4.99.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007332 285.0
TH2_k127_6447828_7 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000001078 266.0
TH2_k127_6447828_8 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001506 266.0
TH2_k127_6447828_9 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000003622 192.0
TH2_k127_6806601_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 3.991e-302 951.0
TH2_k127_6806601_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000004453 198.0
TH2_k127_687384_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 334.0
TH2_k127_687384_1 PFAM Rubrerythrin - GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002253 275.0
TH2_k127_687384_10 lyase activity - - - 0.00000000000003965 76.0
TH2_k127_687384_11 Protein of unknown function (DUF3047) - - - 0.000002145 55.0
TH2_k127_687384_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000003917 251.0
TH2_k127_687384_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003664 240.0
TH2_k127_687384_4 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000000000000000000000000000000000000000000000007443 246.0
TH2_k127_687384_5 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000002965 183.0
TH2_k127_687384_6 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000006924 163.0
TH2_k127_687384_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000001439 141.0
TH2_k127_687384_8 OsmC-like protein K07397 - - 0.000000000000000000000002463 108.0
TH2_k127_687384_9 electron transfer activity K00428 - 1.11.1.5 0.000000000000000000000556 100.0
TH2_k127_6890144_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.161e-237 751.0
TH2_k127_6890144_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 7.168e-226 712.0
TH2_k127_6890144_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 362.0
TH2_k127_6890144_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 351.0
TH2_k127_6890144_12 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 312.0
TH2_k127_6890144_13 PFAM Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007776 257.0
TH2_k127_6890144_14 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006417 243.0
TH2_k127_6890144_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000003657 223.0
TH2_k127_6890144_16 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000003717 219.0
TH2_k127_6890144_17 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001721 228.0
TH2_k127_6890144_18 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000002416 221.0
TH2_k127_6890144_19 NACHT domain - - - 0.0000000000000000000000000000000000000000002043 169.0
TH2_k127_6890144_2 Elongator protein 3, MiaB family, Radical SAM - - - 2.836e-211 666.0
TH2_k127_6890144_20 - - - - 0.000000000000000000000000000000000000002177 170.0
TH2_k127_6890144_21 - - - - 0.00000000000000000000000000000000002129 137.0
TH2_k127_6890144_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000001082 134.0
TH2_k127_6890144_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000003289 131.0
TH2_k127_6890144_24 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000006977 122.0
TH2_k127_6890144_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000006816 117.0
TH2_k127_6890144_26 Tetratricopeptide repeat - - - 0.00000000000000000000000002215 117.0
TH2_k127_6890144_27 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000002368 107.0
TH2_k127_6890144_28 PFAM NADH-ubiquinone plastoquinone oxidoreductase, chain 6 K00339 - 1.6.5.3 0.0000000000000000000005701 108.0
TH2_k127_6890144_29 - - - - 0.00000000000000000003365 97.0
TH2_k127_6890144_3 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 4.273e-204 657.0
TH2_k127_6890144_30 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000002251 83.0
TH2_k127_6890144_31 regulatory protein, FmdB family - - - 0.0000000001332 65.0
TH2_k127_6890144_32 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.0000000006541 64.0
TH2_k127_6890144_33 DsrE/DsrF/DrsH-like family - - - 0.0000002883 58.0
TH2_k127_6890144_35 AAA domain - - - 0.00005129 55.0
TH2_k127_6890144_4 helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 548.0
TH2_k127_6890144_5 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 535.0
TH2_k127_6890144_6 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342,K05575 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 494.0
TH2_k127_6890144_7 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 466.0
TH2_k127_6890144_8 Thermolysin metallopeptidase, alpha-helical domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 476.0
TH2_k127_6890144_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 449.0
TH2_k127_6979419_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.687e-279 881.0
TH2_k127_6979419_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 529.0
TH2_k127_6979419_10 Glycosyltransferase like family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 405.0
TH2_k127_6979419_11 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 383.0
TH2_k127_6979419_12 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 379.0
TH2_k127_6979419_13 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 365.0
TH2_k127_6979419_14 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 332.0
TH2_k127_6979419_15 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001325 281.0
TH2_k127_6979419_16 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000008135 268.0
TH2_k127_6979419_17 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007326 259.0
TH2_k127_6979419_18 Elongation factor G, domain IV K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000004104 232.0
TH2_k127_6979419_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000007729 242.0
TH2_k127_6979419_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 511.0
TH2_k127_6979419_20 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000002909 188.0
TH2_k127_6979419_21 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000002472 190.0
TH2_k127_6979419_22 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000000000003115 152.0
TH2_k127_6979419_23 COG2931 RTX toxins and related Ca2 -binding proteins K01406 - 3.4.24.40 0.000000000000000000000000000000000000002582 158.0
TH2_k127_6979419_24 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000003981 130.0
TH2_k127_6979419_25 Tetratricopeptide repeat - - - 0.0000000000000000000000003072 115.0
TH2_k127_6979419_26 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000001154 95.0
TH2_k127_6979419_27 Helix-turn-helix domain - - - 0.000000000000000002258 96.0
TH2_k127_6979419_28 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000009992 77.0
TH2_k127_6979419_29 Transposase IS200 like K07491 - - 0.0000000002005 63.0
TH2_k127_6979419_3 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 510.0
TH2_k127_6979419_30 Outer membrane protein beta-barrel domain - - - 0.0000002742 59.0
TH2_k127_6979419_31 - - - - 0.0001401 54.0
TH2_k127_6979419_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 449.0
TH2_k127_6979419_5 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 429.0
TH2_k127_6979419_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 427.0
TH2_k127_6979419_7 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 421.0
TH2_k127_6979419_8 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 417.0
TH2_k127_6979419_9 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 408.0
TH2_k127_7043831_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.765e-294 915.0
TH2_k127_7043831_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 8.29e-210 676.0
TH2_k127_7043831_10 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000003159 222.0
TH2_k127_7043831_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001133 232.0
TH2_k127_7043831_12 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000004566 209.0
TH2_k127_7043831_13 S-layer homology domain - - - 0.0000000000000000000000000000000000000000000000000006138 214.0
TH2_k127_7043831_14 Domain of unknown function (DUF4347) - - - 0.0000000000000000000000000000000000000000000000001908 200.0
TH2_k127_7043831_15 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000002265 178.0
TH2_k127_7043831_16 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000005013 159.0
TH2_k127_7043831_17 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.000000000000000000000000000000000000004667 171.0
TH2_k127_7043831_18 cell adhesion - - - 0.00000000000000000000000000000000000001064 170.0
TH2_k127_7043831_19 PFAM FecR protein - - - 0.000000000000000000000007967 114.0
TH2_k127_7043831_2 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 588.0
TH2_k127_7043831_20 PFAM 4Fe-4S ferredoxin - - - 0.000000000000000005991 84.0
TH2_k127_7043831_21 lyase activity - - - 0.00000000000001396 79.0
TH2_k127_7043831_23 PFAM S23 ribosomal protein - - - 0.000000003109 62.0
TH2_k127_7043831_25 PKD domain - - - 0.0003918 55.0
TH2_k127_7043831_3 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 569.0
TH2_k127_7043831_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 568.0
TH2_k127_7043831_5 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 514.0
TH2_k127_7043831_6 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 486.0
TH2_k127_7043831_7 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 293.0
TH2_k127_7043831_8 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001252 265.0
TH2_k127_7043831_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000003694 230.0
TH2_k127_7128396_0 Belongs to the peptidase S8 family K13276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 383.0
TH2_k127_7128396_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001383 284.0
TH2_k127_7128396_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000005467 267.0
TH2_k127_7128396_3 endopeptidase activity - - - 0.00000000000000000000000000000000000000005532 174.0
TH2_k127_7128396_4 PFAM Smr protein MutS2 - - - 0.00001041 48.0
TH2_k127_72889_0 ABC transporter K06158 - - 2.83e-223 709.0
TH2_k127_72889_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.867e-218 683.0
TH2_k127_72889_10 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 397.0
TH2_k127_72889_11 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 355.0
TH2_k127_72889_12 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 339.0
TH2_k127_72889_13 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 338.0
TH2_k127_72889_14 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 302.0
TH2_k127_72889_15 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 306.0
TH2_k127_72889_16 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002276 288.0
TH2_k127_72889_17 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008783 276.0
TH2_k127_72889_18 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002538 274.0
TH2_k127_72889_19 PFAM Rhodanese domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 261.0
TH2_k127_72889_2 Putative diguanylate phosphodiesterase - - - 1.646e-197 645.0
TH2_k127_72889_20 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001709 277.0
TH2_k127_72889_21 Pfam:DUF2029 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002059 265.0
TH2_k127_72889_22 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000458 241.0
TH2_k127_72889_23 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000001219 228.0
TH2_k127_72889_24 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000003003 219.0
TH2_k127_72889_25 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000001137 211.0
TH2_k127_72889_26 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000234 207.0
TH2_k127_72889_27 Dual specificity phosphatase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000009901 188.0
TH2_k127_72889_28 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000011 194.0
TH2_k127_72889_29 SMART Signal transduction response regulator, receiver domain - - - 0.000000000000000000000000000000000000000000000000006673 194.0
TH2_k127_72889_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 550.0
TH2_k127_72889_30 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000001043 188.0
TH2_k127_72889_31 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000006436 191.0
TH2_k127_72889_32 Dual specificity phosphatase, catalytic domain - - - 0.000000000000000000000000000000000000000000000003158 179.0
TH2_k127_72889_33 - - - - 0.00000000000000000000000000000000000000000000005013 179.0
TH2_k127_72889_34 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000001969 160.0
TH2_k127_72889_35 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000234 158.0
TH2_k127_72889_36 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000966 139.0
TH2_k127_72889_37 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000004935 123.0
TH2_k127_72889_38 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000002388 129.0
TH2_k127_72889_39 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000006285 115.0
TH2_k127_72889_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 546.0
TH2_k127_72889_40 Binds the 23S rRNA K02909 - - 0.000000000000000000001282 97.0
TH2_k127_72889_41 mRNA catabolic process K18682 - - 0.00000000000000006062 83.0
TH2_k127_72889_42 Transposase IS200 like - - - 0.0000000000000009097 85.0
TH2_k127_72889_43 protein histidine kinase activity K07648 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.00000000000002071 83.0
TH2_k127_72889_44 SMART Tetratricopeptide - - - 0.00000000000003979 81.0
TH2_k127_72889_45 Uncharacterized ACR, COG1430 K09005 - - 0.000000000006643 78.0
TH2_k127_72889_47 PEGA domain - - - 0.0000001719 65.0
TH2_k127_72889_48 - - - - 0.000003691 51.0
TH2_k127_72889_49 Transposase IS200 like - - - 0.000005122 53.0
TH2_k127_72889_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 502.0
TH2_k127_72889_50 Phage integrase, N-terminal SAM-like domain - - - 0.00001427 48.0
TH2_k127_72889_51 Transposase - - - 0.00004089 48.0
TH2_k127_72889_52 Heat shock 70 kDa protein K04043 - - 0.0001196 53.0
TH2_k127_72889_6 Chromate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 478.0
TH2_k127_72889_7 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 462.0
TH2_k127_72889_8 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 440.0
TH2_k127_72889_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 415.0
TH2_k127_7650821_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 2.788e-210 662.0
TH2_k127_7650821_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 599.0
TH2_k127_7650821_10 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000001245 198.0
TH2_k127_7650821_11 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.0000000000000000000000000000000000000000000000001117 186.0
TH2_k127_7650821_12 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000003549 176.0
TH2_k127_7650821_13 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000002808 158.0
TH2_k127_7650821_14 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000006295 149.0
TH2_k127_7650821_15 HNH nucleases - - - 0.000000000000000000000000000000000001307 141.0
TH2_k127_7650821_16 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000008335 141.0
TH2_k127_7650821_17 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000001367 124.0
TH2_k127_7650821_18 Thiamine-binding protein - - - 0.000000000000000000000000004225 114.0
TH2_k127_7650821_19 Protein tyrosine kinase - - - 0.0000000000000000000000005143 119.0
TH2_k127_7650821_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 486.0
TH2_k127_7650821_20 antisigma factor binding - - - 0.00000014 60.0
TH2_k127_7650821_21 cell division protein FtsL - - - 0.0002146 49.0
TH2_k127_7650821_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 465.0
TH2_k127_7650821_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 447.0
TH2_k127_7650821_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 416.0
TH2_k127_7650821_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 386.0
TH2_k127_7650821_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 338.0
TH2_k127_7650821_8 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 335.0
TH2_k127_7650821_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001034 287.0
TH2_k127_7661945_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1664.0
TH2_k127_7661945_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.768e-314 983.0
TH2_k127_7661945_10 Sigma-54 interaction domain K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 434.0
TH2_k127_7661945_11 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 430.0
TH2_k127_7661945_12 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 417.0
TH2_k127_7661945_13 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 394.0
TH2_k127_7661945_14 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 370.0
TH2_k127_7661945_15 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 356.0
TH2_k127_7661945_16 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 347.0
TH2_k127_7661945_17 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 338.0
TH2_k127_7661945_18 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 349.0
TH2_k127_7661945_19 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 325.0
TH2_k127_7661945_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.94e-291 915.0
TH2_k127_7661945_20 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 336.0
TH2_k127_7661945_21 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 324.0
TH2_k127_7661945_22 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 330.0
TH2_k127_7661945_23 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 329.0
TH2_k127_7661945_24 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 311.0
TH2_k127_7661945_25 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 310.0
TH2_k127_7661945_26 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003572 281.0
TH2_k127_7661945_27 Lytic transglycolase K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007681 274.0
TH2_k127_7661945_28 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005929 284.0
TH2_k127_7661945_29 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001532 267.0
TH2_k127_7661945_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.592e-247 778.0
TH2_k127_7661945_30 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002165 263.0
TH2_k127_7661945_31 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 258.0
TH2_k127_7661945_32 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002981 260.0
TH2_k127_7661945_33 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000008675 262.0
TH2_k127_7661945_34 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000003493 211.0
TH2_k127_7661945_35 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000374 201.0
TH2_k127_7661945_36 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000006082 193.0
TH2_k127_7661945_37 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000001691 193.0
TH2_k127_7661945_38 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000003281 187.0
TH2_k127_7661945_39 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000003475 193.0
TH2_k127_7661945_4 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 4.31e-240 759.0
TH2_k127_7661945_40 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000001437 175.0
TH2_k127_7661945_41 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000007487 171.0
TH2_k127_7661945_42 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000000001092 162.0
TH2_k127_7661945_43 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.000000000000000000000000000000000000000001215 169.0
TH2_k127_7661945_44 cobalamin synthesis protein, P47K - - - 0.000000000000000000000000000000000000000001669 169.0
TH2_k127_7661945_45 HIT domain K02503 - - 0.00000000000000000000000000000000000000000611 156.0
TH2_k127_7661945_46 phosphoribosyl-AMP cyclohydrolase activity K01496,K01497,K01814,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 0.00000000000000000000000000000000000000001543 154.0
TH2_k127_7661945_47 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000007402 156.0
TH2_k127_7661945_48 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000000000000004067 141.0
TH2_k127_7661945_49 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000000000000001265 130.0
TH2_k127_7661945_5 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 3.975e-218 691.0
TH2_k127_7661945_50 PFAM Stress responsive alpha-beta barrel domain protein - - - 0.000000000000000000000000000007311 121.0
TH2_k127_7661945_51 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.00000000000000000000000000009967 128.0
TH2_k127_7661945_52 Polymer-forming cytoskeletal - - - 0.000000000000000000000000001293 118.0
TH2_k127_7661945_54 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000002756 115.0
TH2_k127_7661945_55 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000001689 110.0
TH2_k127_7661945_56 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000003137 101.0
TH2_k127_7661945_57 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000004642 93.0
TH2_k127_7661945_59 - - - - 0.0000000000000002962 82.0
TH2_k127_7661945_6 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 2.872e-212 671.0
TH2_k127_7661945_61 tetratricopeptide repeat - - - 0.00000000002566 72.0
TH2_k127_7661945_62 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000001172 68.0
TH2_k127_7661945_63 Outer membrane lipoprotein - - - 0.000000005999 66.0
TH2_k127_7661945_64 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00001663 51.0
TH2_k127_7661945_66 phosphorelay signal transduction system K07714 - - 0.0003 49.0
TH2_k127_7661945_7 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 558.0
TH2_k127_7661945_8 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 560.0
TH2_k127_7661945_9 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 439.0
TH2_k127_784908_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0 1065.0
TH2_k127_784908_1 PFAM Radical SAM - - - 5.181e-205 648.0
TH2_k127_784908_10 TIGRFAM phosphomethylpyrimidine kinase K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000001531 224.0
TH2_k127_784908_11 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000001829 230.0
TH2_k127_784908_12 Permease YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000001842 233.0
TH2_k127_784908_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000002171 209.0
TH2_k127_784908_14 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000009142 196.0
TH2_k127_784908_15 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000146 201.0
TH2_k127_784908_16 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000003223 186.0
TH2_k127_784908_17 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000002342 179.0
TH2_k127_784908_18 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000001231 174.0
TH2_k127_784908_19 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000001593 172.0
TH2_k127_784908_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 557.0
TH2_k127_784908_20 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000000319 162.0
TH2_k127_784908_21 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000003966 160.0
TH2_k127_784908_22 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0000000000000000000000000000000000001054 165.0
TH2_k127_784908_23 Rhs element Vgr protein K11904 - - 0.000000000000000000000000000001044 134.0
TH2_k127_784908_24 Thioredoxin-like - - - 0.00000000000000000000000000000136 128.0
TH2_k127_784908_25 Bacterial protein of unknown function (DUF922) - - - 0.000000000000000000000003722 110.0
TH2_k127_784908_26 - - - - 0.00000000000000000002356 100.0
TH2_k127_784908_27 - - - - 0.00000000000000000085 93.0
TH2_k127_784908_28 Acetyltransferase (GNAT) domain - - - 0.000000000000001738 86.0
TH2_k127_784908_29 thiamine diphosphate biosynthetic process K03154 - - 0.000000000000003879 78.0
TH2_k127_784908_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 545.0
TH2_k127_784908_30 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00000000000001045 87.0
TH2_k127_784908_31 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000155 69.0
TH2_k127_784908_32 - - - - 0.000000000003905 72.0
TH2_k127_784908_33 - - - - 0.000000000007703 76.0
TH2_k127_784908_34 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.00000003371 59.0
TH2_k127_784908_35 - - - - 0.000000341 55.0
TH2_k127_784908_36 - - - - 0.0000003422 58.0
TH2_k127_784908_4 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 437.0
TH2_k127_784908_5 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 416.0
TH2_k127_784908_6 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 407.0
TH2_k127_784908_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 307.0
TH2_k127_784908_8 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 286.0
TH2_k127_784908_9 2Fe-2S -binding domain K13483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009105 271.0
TH2_k127_7920514_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 480.0
TH2_k127_7920514_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 449.0
TH2_k127_7920514_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000148 287.0
TH2_k127_7920514_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004466 285.0
TH2_k127_7920514_4 Chromate resistance - - - 0.000000000000000000000000000000000000000000003256 168.0
TH2_k127_7922154_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1470.0
TH2_k127_7922154_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 2.476e-246 770.0
TH2_k127_7922154_10 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 321.0
TH2_k127_7922154_11 TIGRFAM MauM NapG family ferredoxin-type protein K02573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 317.0
TH2_k127_7922154_12 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 314.0
TH2_k127_7922154_13 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 318.0
TH2_k127_7922154_14 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001311 259.0
TH2_k127_7922154_15 Poly A polymerase head domain K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000006012 269.0
TH2_k127_7922154_16 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 261.0
TH2_k127_7922154_17 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007709 244.0
TH2_k127_7922154_18 NOG31153 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000001203 232.0
TH2_k127_7922154_19 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000003755 228.0
TH2_k127_7922154_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 544.0
TH2_k127_7922154_20 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000002146 222.0
TH2_k127_7922154_21 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000003664 230.0
TH2_k127_7922154_22 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000003958 220.0
TH2_k127_7922154_23 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000000000000001211 205.0
TH2_k127_7922154_24 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000000000000000000000000000000003172 213.0
TH2_k127_7922154_25 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000002104 202.0
TH2_k127_7922154_26 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000002445 204.0
TH2_k127_7922154_27 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000003625 196.0
TH2_k127_7922154_28 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000003658 186.0
TH2_k127_7922154_29 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000003722 199.0
TH2_k127_7922154_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 470.0
TH2_k127_7922154_30 Domain of unknown function (DUF4145) - - - 0.000000000000000000000000000000000000000000000004194 181.0
TH2_k127_7922154_31 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000003958 175.0
TH2_k127_7922154_32 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000001655 175.0
TH2_k127_7922154_33 Formiminotransferase-cyclodeaminase - - - 0.000000000000000000000000000000000000000009757 162.0
TH2_k127_7922154_34 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000711 156.0
TH2_k127_7922154_35 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.0000000000000000000000000000000000000001149 156.0
TH2_k127_7922154_36 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000001369 144.0
TH2_k127_7922154_37 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000001461 122.0
TH2_k127_7922154_38 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000001093 115.0
TH2_k127_7922154_39 Transcriptional regulator, MerR family - - - 0.0000000000000000000000002098 118.0
TH2_k127_7922154_4 Chalcone and stilbene synthases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 461.0
TH2_k127_7922154_40 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000003298 109.0
TH2_k127_7922154_41 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000004562 117.0
TH2_k127_7922154_42 negative regulation of establishment of protein localization K02570 GO:0003674,GO:0005048,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032879,GO:0032880,GO:0033218,GO:0042277,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0051049,GO:0051051,GO:0051223,GO:0051224,GO:0065007,GO:0070201,GO:0090087,GO:1904950 - 0.0000000000000000000004522 98.0
TH2_k127_7922154_44 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000007086 94.0
TH2_k127_7922154_45 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000008377 83.0
TH2_k127_7922154_46 - - - - 0.0000000000000202 82.0
TH2_k127_7922154_47 integral membrane protein - - - 0.00000000000003143 81.0
TH2_k127_7922154_49 Protein of unknown function (DUF1573) - - - 0.0004488 47.0
TH2_k127_7922154_5 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 446.0
TH2_k127_7922154_50 Protein of unknown function (DUF1573) - - - 0.0006972 44.0
TH2_k127_7922154_6 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 419.0
TH2_k127_7922154_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 368.0
TH2_k127_7922154_8 4Fe-4S binding domain K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 348.0
TH2_k127_7922154_9 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 334.0
TH2_k127_8178153_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.29e-240 758.0
TH2_k127_8178153_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 557.0
TH2_k127_8178153_10 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002715 259.0
TH2_k127_8178153_11 ABC transporter K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000154 249.0
TH2_k127_8178153_12 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007522 250.0
TH2_k127_8178153_13 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000009922 236.0
TH2_k127_8178153_14 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000005498 230.0
TH2_k127_8178153_15 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000000009263 218.0
TH2_k127_8178153_16 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000000000000000008416 214.0
TH2_k127_8178153_17 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000003854 204.0
TH2_k127_8178153_18 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000004274 155.0
TH2_k127_8178153_19 regulation of translation K03530 - - 0.0000000000000000000000000000000000001438 144.0
TH2_k127_8178153_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 540.0
TH2_k127_8178153_20 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000000000000001236 149.0
TH2_k127_8178153_21 PFAM chemotaxis K03406 - - 0.000000000000000000000000000000000003466 142.0
TH2_k127_8178153_22 Transcriptional regulator K02019,K05772 - - 0.0000000000000000000000000000000363 132.0
TH2_k127_8178153_23 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000001674 100.0
TH2_k127_8178153_24 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000002264 103.0
TH2_k127_8178153_25 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000005705 98.0
TH2_k127_8178153_26 Nitrate reductase gamma subunit - - - 0.0000000006386 70.0
TH2_k127_8178153_28 helix_turn_helix multiple antibiotic resistance protein - - - 0.00006322 51.0
TH2_k127_8178153_29 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.0002224 46.0
TH2_k127_8178153_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 510.0
TH2_k127_8178153_4 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 392.0
TH2_k127_8178153_5 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 382.0
TH2_k127_8178153_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 349.0
TH2_k127_8178153_7 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 341.0
TH2_k127_8178153_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 326.0
TH2_k127_8178153_9 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 297.0
TH2_k127_8329603_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1119.0
TH2_k127_8329603_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 6.043e-231 741.0
TH2_k127_8329603_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 318.0
TH2_k127_8329603_11 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 322.0
TH2_k127_8329603_12 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000192 268.0
TH2_k127_8329603_13 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000005009 284.0
TH2_k127_8329603_14 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000004068 245.0
TH2_k127_8329603_15 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003945 247.0
TH2_k127_8329603_16 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000002115 229.0
TH2_k127_8329603_17 PFAM Cupin - - - 0.00000000000000000000000000000000000000000000002683 182.0
TH2_k127_8329603_18 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000001484 154.0
TH2_k127_8329603_19 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000004416 155.0
TH2_k127_8329603_2 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 577.0
TH2_k127_8329603_20 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000001357 142.0
TH2_k127_8329603_21 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000000000008357 127.0
TH2_k127_8329603_22 SMART Cold shock protein K03704 - - 0.00000000000000000000000005109 110.0
TH2_k127_8329603_23 PFAM Sporulation stage II, protein E C-terminal K07315 - 3.1.3.3 0.000000000000000000000001517 115.0
TH2_k127_8329603_24 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000002212 103.0
TH2_k127_8329603_25 Methylamine utilisation protein MauE - - - 0.00000000000000001167 90.0
TH2_k127_8329603_26 RDD family - - - 0.000000000000009297 82.0
TH2_k127_8329603_27 Integral membrane protein TerC family - - - 0.00000000000006845 74.0
TH2_k127_8329603_28 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000002596 78.0
TH2_k127_8329603_29 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000003433 69.0
TH2_k127_8329603_3 Conserved hypothetical protein 698 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 558.0
TH2_k127_8329603_30 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000006748 59.0
TH2_k127_8329603_4 FAD binding domain K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 542.0
TH2_k127_8329603_5 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 489.0
TH2_k127_8329603_6 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 498.0
TH2_k127_8329603_7 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 425.0
TH2_k127_8329603_8 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 409.0
TH2_k127_8329603_9 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 385.0
TH2_k127_8386004_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 4.46e-249 779.0
TH2_k127_8386004_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.532e-246 768.0
TH2_k127_8386004_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 303.0
TH2_k127_8386004_11 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 301.0
TH2_k127_8386004_12 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007169 252.0
TH2_k127_8386004_13 - - - - 0.0000000000000000000000000000000000000000000000000000000002289 220.0
TH2_k127_8386004_14 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000002867 206.0
TH2_k127_8386004_15 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000385 174.0
TH2_k127_8386004_16 Belongs to the Fur family K09825 - - 0.00000000000000000000000000000000455 132.0
TH2_k127_8386004_17 - - - - 0.0000000000000000000000000000001205 132.0
TH2_k127_8386004_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000007363 126.0
TH2_k127_8386004_19 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000004543 114.0
TH2_k127_8386004_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.25e-233 731.0
TH2_k127_8386004_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000008503 117.0
TH2_k127_8386004_21 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000045 105.0
TH2_k127_8386004_22 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000003118 84.0
TH2_k127_8386004_23 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000001962 84.0
TH2_k127_8386004_25 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000326 73.0
TH2_k127_8386004_26 2Fe-2S -binding domain protein - - - 0.000000000002801 74.0
TH2_k127_8386004_27 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000002064 64.0
TH2_k127_8386004_28 SEC-C motif - - - 0.00000008635 58.0
TH2_k127_8386004_29 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000001476 60.0
TH2_k127_8386004_3 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 2.059e-198 627.0
TH2_k127_8386004_30 Chaperone that serves for the intracellular sequestration and transport of Cu( ). Delivers Cu( ) to the copper-exporting P-type ATPase A (CopA) (By similarity) K07213 - - 0.000003876 52.0
TH2_k127_8386004_31 TPR repeat - - - 0.00001435 52.0
TH2_k127_8386004_32 Parallel beta-helix repeats - - - 0.00004775 55.0
TH2_k127_8386004_4 Bacterial regulatory protein, Fis family K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 626.0
TH2_k127_8386004_5 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 580.0
TH2_k127_8386004_6 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 502.0
TH2_k127_8386004_7 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 430.0
TH2_k127_8386004_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 416.0
TH2_k127_8386004_9 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 349.0
TH2_k127_8386006_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.832e-264 832.0
TH2_k127_8386006_1 - - - - 5.613e-244 788.0
TH2_k127_8386006_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000002377 271.0
TH2_k127_8386006_11 Atpase (Aaa K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008708 260.0
TH2_k127_8386006_12 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001551 228.0
TH2_k127_8386006_13 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000007478 237.0
TH2_k127_8386006_14 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000001111 206.0
TH2_k127_8386006_15 NosL - - - 0.00000000000000000000000000000000000000000000000000000006286 200.0
TH2_k127_8386006_16 PFAM Nickel transport complex, NikM subunit, transmembrane - - - 0.000000000000000000000000000000000000000000000000000001805 206.0
TH2_k127_8386006_17 4 iron, 4 sulfur cluster binding K02574 - - 0.000000000000000000000000000000000000000000000000001541 193.0
TH2_k127_8386006_18 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000004104 163.0
TH2_k127_8386006_19 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000000000000000002477 165.0
TH2_k127_8386006_2 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 622.0
TH2_k127_8386006_20 Endoribonuclease L-PSP K09021,K09022 GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.99.10 0.000000000000000000000000000000000000000002219 163.0
TH2_k127_8386006_21 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000002996 161.0
TH2_k127_8386006_22 NosL - - - 0.000000000000000000000000000000000003695 142.0
TH2_k127_8386006_23 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000003213 120.0
TH2_k127_8386006_24 PFAM TfoX N-terminal domain K07343 - - 0.000000000000000000000000000843 122.0
TH2_k127_8386006_25 - - - - 0.000000000000000000000000007513 113.0
TH2_k127_8386006_26 - - - - 0.00000000000000000000000001457 118.0
TH2_k127_8386006_27 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000185 117.0
TH2_k127_8386006_28 Thioredoxin-like - - - 0.0000000000000000000000003967 115.0
TH2_k127_8386006_29 Transposase IS200 like K07491 - - 0.000000000000007081 75.0
TH2_k127_8386006_3 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 467.0
TH2_k127_8386006_30 Domain of unknown function (DUF4136) - - - 0.00000000001343 72.0
TH2_k127_8386006_31 Protein of unknown function (DUF2892) - - - 0.00000000009761 68.0
TH2_k127_8386006_32 Predicted membrane protein (DUF2318) - - - 0.0000000199 61.0
TH2_k127_8386006_33 transport protein ExbD K03559 - - 0.00000003242 60.0
TH2_k127_8386006_34 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.0000003772 53.0
TH2_k127_8386006_35 Protein of unknown function (DUF2892) - - - 0.000002012 55.0
TH2_k127_8386006_36 Transposase IS200 like K07491 - - 0.00001286 48.0
TH2_k127_8386006_37 Redoxin - - - 0.00006577 52.0
TH2_k127_8386006_38 Predicted membrane protein (DUF2318) - - - 0.00007327 51.0
TH2_k127_8386006_39 YHS domain - - - 0.0001761 52.0
TH2_k127_8386006_4 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 445.0
TH2_k127_8386006_40 Sh3 type 3 domain protein - - - 0.0003556 52.0
TH2_k127_8386006_5 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 415.0
TH2_k127_8386006_6 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 394.0
TH2_k127_8386006_7 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 344.0
TH2_k127_8386006_8 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 312.0
TH2_k127_8386006_9 proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 294.0
TH2_k127_86162_0 membrane protein involved in D-alanine export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 481.0
TH2_k127_86162_1 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 480.0
TH2_k127_86162_2 Belongs to the heme-copper respiratory oxidase family K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000186 215.0
TH2_k127_86162_3 - - - - 0.00000000000000000000000000000000000000000000000000001623 207.0
TH2_k127_86162_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000006914 133.0
TH2_k127_86162_5 Prokaryotic cytochrome b561 - - - 0.00000000008673 70.0
TH2_k127_942735_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 499.0
TH2_k127_942735_1 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 441.0
TH2_k127_942735_2 EcsC protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 297.0
TH2_k127_942735_3 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004749 238.0
TH2_k127_942735_4 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000002227 205.0
TH2_k127_942735_5 Carboxypeptidase - - - 0.00000000000000000000000005058 125.0
TH2_k127_942735_6 NmrA-like family - - - 0.00000000000000000000003905 111.0
TH2_k127_942735_7 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000002011 84.0
TH2_k127_942735_8 Protein of unknown function (DUF1549) - - - 0.000000000005878 75.0
TH2_k127_97174_0 DEAD DEAH box K03724 - - 0.0 1572.0
TH2_k127_97174_1 Molecular chaperone. Has ATPase activity K04079 - - 2.078e-258 810.0
TH2_k127_97174_10 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002857 257.0
TH2_k127_97174_11 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000002682 239.0
TH2_k127_97174_12 RibD C-terminal domain K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000001593 207.0
TH2_k127_97174_13 - - - - 0.000000000000000000000000000000000000000000000000000000003612 205.0
TH2_k127_97174_14 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000004205 198.0
TH2_k127_97174_15 methylamine metabolic process K15977 - - 0.000000000000000000000000000000000000000000195 165.0
TH2_k127_97174_16 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000005825 160.0
TH2_k127_97174_17 Sulphur transport - - - 0.00000000000000000000000000000000004396 140.0
TH2_k127_97174_18 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000004522 135.0
TH2_k127_97174_19 Hep Hag repeat protein - - - 0.00000000000000000000000000000003593 140.0
TH2_k127_97174_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 512.0
TH2_k127_97174_20 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000005056 136.0
TH2_k127_97174_21 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000002994 119.0
TH2_k127_97174_22 Cytochrome P460 - - - 0.00000000000000000000000003011 114.0
TH2_k127_97174_24 Glutathione peroxidase - - - 0.000000000000000000000004745 111.0
TH2_k127_97174_25 Hep Hag repeat protein - - - 0.000000000000000000001079 108.0
TH2_k127_97174_26 - - - - 0.0000000000000000001845 90.0
TH2_k127_97174_28 Protein of unknown function (DUF3570) - - - 0.0000000000000001618 93.0
TH2_k127_97174_29 Tetratricopeptide repeat - - - 0.00000000000007988 80.0
TH2_k127_97174_3 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 436.0
TH2_k127_97174_30 Cytochrome P460 - - - 0.0000000000001462 71.0
TH2_k127_97174_31 Tetratricopeptide repeat - - - 0.0000000000003481 78.0
TH2_k127_97174_32 - - - - 0.0000001457 57.0
TH2_k127_97174_33 Domain of unknown function (DUF4266) - - - 0.00005705 54.0
TH2_k127_97174_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 347.0
TH2_k127_97174_5 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 315.0
TH2_k127_97174_6 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 299.0
TH2_k127_97174_7 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 267.0
TH2_k127_97174_8 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003383 273.0
TH2_k127_97174_9 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001134 261.0