Overview

ID MAG03929
Name TH2_bin.8
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA9159
Genus
Species
Assembly information
Completeness (%) 67.97
Contamination (%) 0.57
GC content (%) 56.0
N50 (bp) 4,197
Genome size (bp) 1,530,154

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1637

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1011226_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.796e-266 835.0
TH2_k127_1011226_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000001716 109.0
TH2_k127_1011226_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000005015 107.0
TH2_k127_1011820_0 4Fe-4S dicluster domain - - - 3.949e-202 634.0
TH2_k127_1011820_1 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 442.0
TH2_k127_1011820_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000001618 183.0
TH2_k127_1011820_3 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000003513 180.0
TH2_k127_1011820_4 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.0000000000000000000000000000000000000001043 158.0
TH2_k127_1011820_5 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000139 141.0
TH2_k127_1011820_6 lyase activity - - - 0.00000000000000006969 85.0
TH2_k127_1036084_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.059e-240 752.0
TH2_k127_1036084_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000002642 141.0
TH2_k127_1036084_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000005709 66.0
TH2_k127_1036084_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0004983 49.0
TH2_k127_1080704_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 330.0
TH2_k127_1080704_1 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001217 271.0
TH2_k127_1080704_2 PDGLE domain K02007 - - 0.0000000000000000000000000000002698 127.0
TH2_k127_1089950_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.875e-232 733.0
TH2_k127_1089950_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 375.0
TH2_k127_1109925_0 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 348.0
TH2_k127_1109925_1 Pilus assembly protein, PilP K02665 - - 0.000000001382 66.0
TH2_k127_111642_0 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 395.0
TH2_k127_111642_1 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000005005 230.0
TH2_k127_111642_2 PSP1 domain protein - - - 0.00000000000000000001993 95.0
TH2_k127_1215109_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.246e-278 865.0
TH2_k127_1215109_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000058 214.0
TH2_k127_1215109_2 Putative regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000001665 204.0
TH2_k127_1250123_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 457.0
TH2_k127_1250123_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000005937 114.0
TH2_k127_1250123_2 Rubrerythrin - - - 0.0000000000005427 75.0
TH2_k127_1252185_0 NAD-dependent K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 542.0
TH2_k127_1252185_1 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 391.0
TH2_k127_1252185_2 PFAM DNA polymerase beta domain protein region K07075 - - 0.00000000000000000000000003149 112.0
TH2_k127_1252185_3 Protein of unknown function DUF86 - - - 0.000000000000001099 81.0
TH2_k127_1264571_0 hexose biosynthetic process K01810 - 5.3.1.9 2.408e-287 889.0
TH2_k127_1264571_1 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 416.0
TH2_k127_1264571_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000008982 181.0
TH2_k127_1264571_3 - - - - 0.00000000709 64.0
TH2_k127_1266647_0 helicase superfamily c-terminal domain - - - 0.0 1445.0
TH2_k127_1291085_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 8.811e-215 678.0
TH2_k127_1291085_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 523.0
TH2_k127_1291085_2 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000005989 216.0
TH2_k127_1296061_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000004729 267.0
TH2_k127_1296061_1 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000006258 210.0
TH2_k127_1296061_2 OstA-like protein K09774 - - 0.000000000000000000000000000002426 126.0
TH2_k127_1296061_3 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000003196 117.0
TH2_k127_1296061_4 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00001025 54.0
TH2_k127_1348916_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.125e-233 739.0
TH2_k127_1348916_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 446.0
TH2_k127_1348916_2 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000137 248.0
TH2_k127_1348916_3 Rdx family K07401 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009898,GO:0010941,GO:0016020,GO:0030334,GO:0030335,GO:0031224,GO:0031226,GO:0031235,GO:0031344,GO:0031346,GO:0032879,GO:0040012,GO:0040017,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0044087,GO:0044089,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051270,GO:0051272,GO:0051489,GO:0051491,GO:0060491,GO:0060548,GO:0065007,GO:0071944,GO:0098552,GO:0098562,GO:0120032,GO:0120034,GO:0120035,GO:2000145,GO:2000147 - 0.000002425 55.0
TH2_k127_1373770_0 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 450.0
TH2_k127_1373770_1 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 314.0
TH2_k127_1373770_2 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 291.0
TH2_k127_1373770_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000003376 218.0
TH2_k127_1373770_4 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000001629 211.0
TH2_k127_1373770_5 - - - - 0.0003504 44.0
TH2_k127_1382899_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 319.0
TH2_k127_1382899_1 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.000000000155 67.0
TH2_k127_1389412_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 526.0
TH2_k127_1389412_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 451.0
TH2_k127_1442158_0 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 360.0
TH2_k127_1442158_1 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000004576 268.0
TH2_k127_1442158_2 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.00000000000000000000000000000000872 132.0
TH2_k127_1477854_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 1.495e-245 781.0
TH2_k127_1519618_0 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005603 274.0
TH2_k127_1519618_1 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000004364 254.0
TH2_k127_1519618_2 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004598 256.0
TH2_k127_1519618_3 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000002397 63.0
TH2_k127_1533264_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 454.0
TH2_k127_1533264_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 382.0
TH2_k127_1533264_2 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 327.0
TH2_k127_1533264_3 Proteasome subunit K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001174 263.0
TH2_k127_1533264_4 PFAM SNARE associated Golgi protein - - - 0.000000000000002014 77.0
TH2_k127_1539995_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 595.0
TH2_k127_1539995_1 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 399.0
TH2_k127_1556654_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 474.0
TH2_k127_1556654_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 402.0
TH2_k127_1556654_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 336.0
TH2_k127_1556654_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000002302 163.0
TH2_k127_1556654_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000000000000002067 156.0
TH2_k127_1556654_5 Abortive infection protein K07052 - - 0.000006327 51.0
TH2_k127_1561545_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 484.0
TH2_k127_1561545_1 Belongs to the SfsA family K06206 - - 0.000000000000000000000000000000000000000000000000000000003372 207.0
TH2_k127_1561545_2 - - - - 0.0000000000004363 70.0
TH2_k127_1561545_3 - - - - 0.00000009365 57.0
TH2_k127_1578183_0 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 342.0
TH2_k127_1578183_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 287.0
TH2_k127_1578183_2 ferrous iron binding K06990,K09141 - - 0.00000000000000008308 82.0
TH2_k127_1587926_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 5.706e-229 731.0
TH2_k127_1587926_1 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001113 284.0
TH2_k127_1587926_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 261.0
TH2_k127_1587926_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007344 244.0
TH2_k127_1587926_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000005674 82.0
TH2_k127_1611666_0 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22341 - 1.17.1.11,1.17.1.9 1.202e-199 636.0
TH2_k127_1611666_1 photosystem II stabilization K02237 - - 0.00000000000000000000000000000000000000000000000001634 192.0
TH2_k127_1611666_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000003658 165.0
TH2_k127_1611666_3 - - - - 0.000000000000000000000000000002678 122.0
TH2_k127_1640576_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 557.0
TH2_k127_1640576_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000001602 246.0
TH2_k127_1640576_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000005688 83.0
TH2_k127_1658954_0 MMPL family K07003 - - 8.424e-289 906.0
TH2_k127_1658954_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 415.0
TH2_k127_1658954_2 Outer membrane lipoprotein-sorting protein - - - 0.0000000002628 67.0
TH2_k127_1695151_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 6.056e-228 717.0
TH2_k127_1695151_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 520.0
TH2_k127_1695151_2 PFAM type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 496.0
TH2_k127_1695151_3 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.00000000000000000000000004252 111.0
TH2_k127_1695151_4 Modulates RecA activity K03565 - - 0.00000006961 61.0
TH2_k127_1697485_0 3-deoxy-D-manno-octulosonic-acid transferase K02527 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001115 263.0
TH2_k127_1697485_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000001423 262.0
TH2_k127_1713177_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 5.431e-272 861.0
TH2_k127_1713177_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 492.0
TH2_k127_1713177_2 heat shock protein binding - - - 0.000000000009913 75.0
TH2_k127_1715587_0 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 316.0
TH2_k127_1715587_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000006975 170.0
TH2_k127_1715587_2 - - - - 0.00000000000000000000000000000001112 132.0
TH2_k127_1715587_3 PFAM 4Fe-4S binding domain - - - 0.00000000000000000000000000000001714 130.0
TH2_k127_1715587_4 SpoVT / AbrB like domain - - - 0.000000000000000000000001212 106.0
TH2_k127_1715587_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.00000000000000000003283 89.0
TH2_k127_171888_0 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 4.13e-203 654.0
TH2_k127_171888_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000001666 222.0
TH2_k127_171888_2 Biogenesis protein K09792 - - 0.0000000000000000000000000000000000000000000000000000000000007975 218.0
TH2_k127_171888_3 FixH - - - 0.000000000000000000000000007517 114.0
TH2_k127_171888_4 FixH - - - 0.0000000000000004167 84.0
TH2_k127_1766056_0 Ribosomal protein S1 K02945,K03527,K07571 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 385.0
TH2_k127_1766056_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 294.0
TH2_k127_1783865_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 430.0
TH2_k127_1813101_0 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000007015 184.0
TH2_k127_1830450_0 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 409.0
TH2_k127_1830450_1 Nitrogen regulatory protein P-II K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000000000000000000007501 153.0
TH2_k127_1830450_2 FMN binding - - - 0.00000000000000000001721 91.0
TH2_k127_1832511_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 453.0
TH2_k127_1832511_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000125 290.0
TH2_k127_1832511_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000001222 144.0
TH2_k127_1833304_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.382e-265 827.0
TH2_k127_1833304_1 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000115 105.0
TH2_k127_1833304_2 Cell Wall K01448 - 3.5.1.28 0.000008177 57.0
TH2_k127_1833304_3 Recombinase - - - 0.0003881 44.0
TH2_k127_1933811_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 319.0
TH2_k127_1933811_1 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000001098 195.0
TH2_k127_1933811_3 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000001028 69.0
TH2_k127_193671_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.007e-223 709.0
TH2_k127_193671_1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 347.0
TH2_k127_193671_2 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001362 263.0
TH2_k127_193671_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000008685 223.0
TH2_k127_193671_4 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000009741 60.0
TH2_k127_1938512_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1029.0
TH2_k127_1938512_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 342.0
TH2_k127_1938512_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 305.0
TH2_k127_1938512_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001513 256.0
TH2_k127_1938512_4 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000289 182.0
TH2_k127_1938512_5 - - - - 0.00000000000000000000000000000000000003945 154.0
TH2_k127_1938512_6 ApbE family K03734 - 2.7.1.180 0.0000000000000000000000000000006357 130.0
TH2_k127_1938512_7 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000005437 117.0
TH2_k127_1938512_8 cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000002377 104.0
TH2_k127_1941870_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 525.0
TH2_k127_1941870_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000001364 228.0
TH2_k127_1941870_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000001684 231.0
TH2_k127_1941870_3 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000001112 165.0
TH2_k127_1941870_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000551 102.0
TH2_k127_1956846_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002107 288.0
TH2_k127_1956846_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000518 242.0
TH2_k127_199958_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1130.0
TH2_k127_199958_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 362.0
TH2_k127_199958_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000002548 183.0
TH2_k127_199958_3 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000087 164.0
TH2_k127_199958_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000008646 87.0
TH2_k127_200980_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 441.0
TH2_k127_200980_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 352.0
TH2_k127_200980_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000001427 221.0
TH2_k127_200980_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000004068 210.0
TH2_k127_200980_4 cheY-homologous receiver domain - - - 0.0000006275 54.0
TH2_k127_2042626_0 Citrate synthase, C-terminal domain K01647,K01659 - 2.3.3.1,2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 401.0
TH2_k127_2042626_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 390.0
TH2_k127_2042626_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000107 208.0
TH2_k127_2042626_3 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000009626 143.0
TH2_k127_2042626_4 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000002898 106.0
TH2_k127_207186_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 503.0
TH2_k127_207186_1 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000001766 133.0
TH2_k127_2082536_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 3.651e-227 713.0
TH2_k127_2082536_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000002225 201.0
TH2_k127_2082536_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000009017 145.0
TH2_k127_2155025_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 524.0
TH2_k127_2155025_1 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 363.0
TH2_k127_2155025_2 Thiamine biosynthesis protein (ThiI) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 307.0
TH2_k127_2155025_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000002236 171.0
TH2_k127_2155025_4 Transcriptional regulator, MerR family - - - 0.000000000000000000000000000000000008741 141.0
TH2_k127_2155025_5 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0000000000007236 71.0
TH2_k127_2155025_6 Tetratricopeptide repeat protein - - - 0.0002532 48.0
TH2_k127_2167596_0 ATPase BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 493.0
TH2_k127_2167596_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 347.0
TH2_k127_2167596_2 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.00000000000000000000000000000000001506 145.0
TH2_k127_2184562_0 Telomere recombination K04656 - - 2.055e-227 724.0
TH2_k127_2184562_1 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004393 249.0
TH2_k127_2211367_1 diguanylate cyclase K13590 - 2.7.7.65 0.0000000000000000000000000005648 120.0
TH2_k127_2211367_2 - - - - 0.000003752 49.0
TH2_k127_2227530_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 4.623e-265 828.0
TH2_k127_2227530_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.654e-210 659.0
TH2_k127_2227530_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 362.0
TH2_k127_2227530_3 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 311.0
TH2_k127_2227530_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000004128 229.0
TH2_k127_2227530_5 ACT domain - - - 0.00000000000000000000000000000000000000000000000000000000005134 207.0
TH2_k127_2233324_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.225e-228 717.0
TH2_k127_2233324_1 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 526.0
TH2_k127_2233324_2 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 398.0
TH2_k127_2233324_3 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000006297 238.0
TH2_k127_2233324_4 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000001771 198.0
TH2_k127_2233324_5 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.00000000000000000000000000000000000001547 146.0
TH2_k127_2233324_6 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000000001149 145.0
TH2_k127_2233324_7 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000002703 145.0
TH2_k127_2340771_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 521.0
TH2_k127_2340771_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000001432 176.0
TH2_k127_23433_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 532.0
TH2_k127_23433_1 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 334.0
TH2_k127_23433_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000008063 127.0
TH2_k127_2351557_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.38e-220 689.0
TH2_k127_2351557_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 451.0
TH2_k127_2351557_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 451.0
TH2_k127_2351557_3 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 369.0
TH2_k127_2351557_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009184 272.0
TH2_k127_2351557_5 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000003663 248.0
TH2_k127_2351557_6 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000003883 181.0
TH2_k127_2351557_7 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.00000000000000000000000000000000000006826 147.0
TH2_k127_2351557_8 Belongs to the 'phage' integrase family - - - 0.00003259 46.0
TH2_k127_2433718_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 457.0
TH2_k127_2433718_1 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 332.0
TH2_k127_2433718_2 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000178 218.0
TH2_k127_2433718_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000009631 202.0
TH2_k127_2433718_4 carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000009164 121.0
TH2_k127_2464854_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 473.0
TH2_k127_2464854_1 PFAM Glycosyl transferase family 2 K12992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 312.0
TH2_k127_2464854_2 sugar transferase K00996 - 2.7.8.6 0.00000000000002999 77.0
TH2_k127_2500781_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 419.0
TH2_k127_2500781_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 384.0
TH2_k127_2500781_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 296.0
TH2_k127_2500781_3 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000001007 169.0
TH2_k127_2504447_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 465.0
TH2_k127_2504447_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000001689 122.0
TH2_k127_2504447_2 - - - - 0.00002464 52.0
TH2_k127_2532140_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 367.0
TH2_k127_2532140_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006622 241.0
TH2_k127_2532140_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000001194 202.0
TH2_k127_2532140_3 Phospholipid methyltransferase - - - 0.00000000000000000006341 98.0
TH2_k127_2532140_4 response to heat - - - 0.00003748 50.0
TH2_k127_2533902_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 315.0
TH2_k127_2533902_1 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000003545 230.0
TH2_k127_2533902_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000003183 179.0
TH2_k127_2533902_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000009737 100.0
TH2_k127_2533902_4 SpoVT / AbrB like domain - - - 0.00000000002462 67.0
TH2_k127_2533902_5 Addiction module toxin RelE StbE family - - - 0.00000000004642 66.0
TH2_k127_2579038_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 417.0
TH2_k127_2579038_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 357.0
TH2_k127_2579038_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000997 147.0
TH2_k127_2579038_3 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000001788 132.0
TH2_k127_2579038_4 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000009817 75.0
TH2_k127_2579038_5 NusG domain II - - - 0.0000000003586 66.0
TH2_k127_2601741_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 446.0
TH2_k127_2601741_1 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 372.0
TH2_k127_2622197_0 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 571.0
TH2_k127_2622197_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 336.0
TH2_k127_2622197_2 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005623 242.0
TH2_k127_2622197_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000004021 192.0
TH2_k127_2622197_4 Response regulator receiver domain - - - 0.000000000000000000000000000000009863 131.0
TH2_k127_2632548_0 Valyl tRNA synthetase tRNA binding arm K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1052.0
TH2_k127_2639868_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.875e-260 822.0
TH2_k127_2639868_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.873e-194 613.0
TH2_k127_2639868_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 548.0
TH2_k127_2639868_3 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 321.0
TH2_k127_2646823_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000001631 234.0
TH2_k127_2646823_1 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000007252 97.0
TH2_k127_2646823_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000009588 72.0
TH2_k127_2667974_0 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 571.0
TH2_k127_2667974_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 338.0
TH2_k127_2667974_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000001121 190.0
TH2_k127_2667974_3 GAF domain K02584 - - 0.0000000000000000000000000000000000000000007695 160.0
TH2_k127_2717330_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 342.0
TH2_k127_2717330_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002569 297.0
TH2_k127_2717330_2 HEAT repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001905 292.0
TH2_k127_2717330_3 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000188 233.0
TH2_k127_2717330_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000001443 169.0
TH2_k127_2717330_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000008634 140.0
TH2_k127_2717330_6 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000001365 130.0
TH2_k127_2734926_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 519.0
TH2_k127_2734926_1 6-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001997 260.0
TH2_k127_2734926_2 Peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.0002518 51.0
TH2_k127_275633_0 DJ-1/PfpI family K03152,K05520,K05687 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000006846 241.0
TH2_k127_275633_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008462 238.0
TH2_k127_275633_2 Cytochrome P460 - - - 0.00000000000000000000000000000000009238 139.0
TH2_k127_2786166_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 8.706e-200 629.0
TH2_k127_2786166_1 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000000006023 175.0
TH2_k127_2786166_2 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000001972 155.0
TH2_k127_2786166_3 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000003195 126.0
TH2_k127_2786166_4 - - - - 0.00000000000000000006359 96.0
TH2_k127_27959_0 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 1.96e-201 635.0
TH2_k127_27959_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 490.0
TH2_k127_27959_2 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 367.0
TH2_k127_27959_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 350.0
TH2_k127_27959_4 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000002911 195.0
TH2_k127_27959_5 PFAM pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000000000009536 145.0
TH2_k127_28357_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 389.0
TH2_k127_28357_1 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000009743 164.0
TH2_k127_28357_2 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000007145 111.0
TH2_k127_2877561_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 323.0
TH2_k127_2877561_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000344 206.0
TH2_k127_2877561_2 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000003279 168.0
TH2_k127_2877561_3 PFAM PHP domain - - - 0.00000000000000000000000000000000000000169 154.0
TH2_k127_2909303_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 4.265e-276 851.0
TH2_k127_2909303_1 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 324.0
TH2_k127_2917454_0 ABC transporter transmembrane region K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 511.0
TH2_k127_2917454_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005016 278.0
TH2_k127_2917454_2 Methyltransferase type 11 K20444 - - 0.0000000000000000000000000000001449 131.0
TH2_k127_2917454_3 Protein of unknown function (DUF3108) - - - 0.00000000000000000000006085 99.0
TH2_k127_2917454_4 Glycosyl transferase 4-like - - - 0.0001261 51.0
TH2_k127_2933549_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 441.0
TH2_k127_2933549_1 Predicted membrane protein (DUF2318) - - - 0.000000000000000000000000000000000002751 147.0
TH2_k127_2978024_0 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005668 260.0
TH2_k127_2978024_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000003901 200.0
TH2_k127_2978024_2 Belongs to the UPF0502 family K09915 - - 0.0000000000000000000000000000000000000000598 156.0
TH2_k127_2990102_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 478.0
TH2_k127_2990102_1 PHB de-polymerase C-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 455.0
TH2_k127_2990102_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 330.0
TH2_k127_2990102_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 321.0
TH2_k127_2990102_4 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 289.0
TH2_k127_2990102_5 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0000000000000000000000000212 108.0
TH2_k127_2990102_6 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000000000000000000003913 108.0
TH2_k127_3003979_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000002092 72.0
TH2_k127_3003979_1 Peptidase family M48 - - - 0.00000000157 69.0
TH2_k127_3043652_0 Flavodoxin - - - 1.383e-200 630.0
TH2_k127_3043652_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 322.0
TH2_k127_3043652_2 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.0000000000000000000000000000000000000000000000003175 179.0
TH2_k127_3043652_3 Cold shock K03704 - - 0.00000000000000000000000001307 109.0
TH2_k127_3043652_4 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000008131 77.0
TH2_k127_3043652_5 Fe-S protein K06938 - - 0.0000000007086 61.0
TH2_k127_3047583_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 1.054e-258 815.0
TH2_k127_3047583_1 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000000000006063 127.0
TH2_k127_3082063_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.558e-296 928.0
TH2_k127_3082063_1 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000002083 251.0
TH2_k127_3082063_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000001372 138.0
TH2_k127_3100183_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 575.0
TH2_k127_3100183_1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000004156 176.0
TH2_k127_3100183_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000003051 145.0
TH2_k127_3141991_0 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000001626 182.0
TH2_k127_3146599_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.725e-239 750.0
TH2_k127_3146599_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.253e-238 745.0
TH2_k127_3146599_2 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 347.0
TH2_k127_3146599_3 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 332.0
TH2_k127_3146599_4 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000004235 250.0
TH2_k127_3152859_0 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 377.0
TH2_k127_3152859_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 342.0
TH2_k127_3152859_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001842 262.0
TH2_k127_3152859_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000002443 231.0
TH2_k127_3152859_4 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000002431 205.0
TH2_k127_3152859_5 - - - - 0.00000000000000000000000000000000000000009131 172.0
TH2_k127_3152859_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000215 156.0
TH2_k127_3153124_0 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 512.0
TH2_k127_3153124_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000009825 119.0
TH2_k127_3153124_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000009633 109.0
TH2_k127_3204449_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 420.0
TH2_k127_3204449_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 401.0
TH2_k127_3204449_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000698 236.0
TH2_k127_3204449_3 PFAM Class I peptide chain release factor - - - 0.00000000000000000000000000000000000007935 146.0
TH2_k127_3232489_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 449.0
TH2_k127_3232489_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000003715 261.0
TH2_k127_3232489_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000001762 203.0
TH2_k127_3232489_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000001578 105.0
TH2_k127_3232489_4 NeuB family K03856 - 2.5.1.54 0.000000000000000009392 83.0
TH2_k127_3247139_0 Phosphoglycerate kinase K00927 - 2.7.2.3 5.053e-204 640.0
TH2_k127_3247139_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 482.0
TH2_k127_3247139_2 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 354.0
TH2_k127_3247139_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000002696 213.0
TH2_k127_3247139_4 - - - - 0.000000005035 63.0
TH2_k127_3264987_0 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 307.0
TH2_k127_3264987_1 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000005599 219.0
TH2_k127_327892_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 406.0
TH2_k127_327892_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000001086 127.0
TH2_k127_327892_2 - - - - 0.000000000000000000001336 99.0
TH2_k127_3287257_0 PFAM Type II secretion system protein E K02454 - - 1.886e-196 625.0
TH2_k127_3287257_1 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 522.0
TH2_k127_3287257_2 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000007546 161.0
TH2_k127_3287257_3 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.00000000000000000000002045 109.0
TH2_k127_3287329_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 481.0
TH2_k127_3287329_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000001374 115.0
TH2_k127_3302522_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 496.0
TH2_k127_3302522_1 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000127 192.0
TH2_k127_3302522_2 Protein of unknown function (DUF3187) - - - 0.00000000000000000000002174 111.0
TH2_k127_3302522_3 Histidine kinase - - - 0.000000000002032 75.0
TH2_k127_3302522_4 - - - - 0.0005507 48.0
TH2_k127_3311567_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 5.576e-222 697.0
TH2_k127_3311567_1 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 468.0
TH2_k127_3311567_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 407.0
TH2_k127_3311567_3 NOG31153 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008449 257.0
TH2_k127_3311567_5 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000005007 121.0
TH2_k127_3311567_6 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000001177 80.0
TH2_k127_3311567_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000003559 61.0
TH2_k127_3320753_0 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006653 263.0
TH2_k127_3320753_1 calcium, potassium:sodium antiporter activity K07301 - - 0.0000000000000000000000000000000000000000000000000005036 188.0
TH2_k127_3320753_2 - - - - 0.0000000000000000008602 93.0
TH2_k127_3320753_4 iron ion homeostasis - - - 0.00006608 51.0
TH2_k127_3325727_0 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 471.0
TH2_k127_3325727_1 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000002063 163.0
TH2_k127_3325727_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000002958 126.0
TH2_k127_3325727_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000001857 90.0
TH2_k127_3325727_4 OsmC-like protein K07397 - - 0.0005401 43.0
TH2_k127_3336915_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 7.863e-234 740.0
TH2_k127_3349301_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 1.604e-268 839.0
TH2_k127_3349301_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 562.0
TH2_k127_3349301_2 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000000003476 232.0
TH2_k127_3349301_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000001089 185.0
TH2_k127_3349301_4 Ferredoxin K17992 - 1.12.1.3 0.00000000000000000000000000000000000000000002858 164.0
TH2_k127_3349301_5 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000009365 71.0
TH2_k127_3349301_6 - - - - 0.00006489 55.0
TH2_k127_3351923_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003043 246.0
TH2_k127_3351923_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000001048 144.0
TH2_k127_3351923_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000001199 146.0
TH2_k127_3351923_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000009314 130.0
TH2_k127_3354701_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 422.0
TH2_k127_3354701_1 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001247 270.0
TH2_k127_3354701_2 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000489 253.0
TH2_k127_3354701_3 His Kinase A (phosphoacceptor) domain K10715 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000005383 257.0
TH2_k127_3361701_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000331 295.0
TH2_k127_3361701_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000004637 125.0
TH2_k127_3361701_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000007656 100.0
TH2_k127_3380874_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 529.0
TH2_k127_3380874_1 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 327.0
TH2_k127_3380874_2 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000003075 226.0
TH2_k127_3390771_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.887e-292 905.0
TH2_k127_3390771_1 Dehydratase family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 339.0
TH2_k127_3390771_2 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001632 256.0
TH2_k127_3390771_3 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000003656 209.0
TH2_k127_3390771_4 - - - - 0.00000000000000000000000000000000000000000000009285 172.0
TH2_k127_3390771_5 - - - - 0.0000000000000000000003934 100.0
TH2_k127_3460556_0 carbamoyl transferase, NodU family K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004287 243.0
TH2_k127_3460556_1 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000007426 166.0
TH2_k127_3460556_2 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000006641 91.0
TH2_k127_3460556_3 - - - - 0.0000000000002909 70.0
TH2_k127_3479416_0 auxin-activated signaling pathway K07088 - - 0.0000000000000000000000000000000000000000000000000000007968 203.0
TH2_k127_3479416_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000003081 168.0
TH2_k127_3518434_0 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000003227 254.0
TH2_k127_3518434_1 Belongs to the MurCDEF family - - - 0.00000000000000000000000000000000000000000000000000000000000311 220.0
TH2_k127_3524580_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 4.411e-220 691.0
TH2_k127_3524580_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 428.0
TH2_k127_3524580_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 431.0
TH2_k127_3524580_3 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000007623 241.0
TH2_k127_3524580_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000005615 80.0
TH2_k127_35423_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 563.0
TH2_k127_35423_1 4 iron, 4 sulfur cluster binding K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 356.0
TH2_k127_35423_2 - - - - 0.0000000000000000000000000000000000000000000000000001945 188.0
TH2_k127_35423_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000005898 179.0
TH2_k127_35423_4 Universal stress protein family - - - 0.0000000000000000000000000000000000003584 145.0
TH2_k127_35423_5 Putative beta-barrel porin 2 K20920 - - 0.0000000005357 67.0
TH2_k127_3551523_0 General secretory system II, protein E domain protein K02652 - - 2.077e-206 656.0
TH2_k127_3551523_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 529.0
TH2_k127_3551523_2 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 371.0
TH2_k127_3551523_3 His Kinase A (phosphoacceptor) domain K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000002085 225.0
TH2_k127_3574089_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 563.0
TH2_k127_3574089_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000008352 127.0
TH2_k127_3600772_0 FAD binding domain K00278 - 1.4.3.16 6.365e-202 641.0
TH2_k127_3600772_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 418.0
TH2_k127_361988_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 343.0
TH2_k127_361988_1 LysM domain K01449,K19223 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000005713 245.0
TH2_k127_361988_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000001119 179.0
TH2_k127_361988_3 - - - - 0.0001034 49.0
TH2_k127_3623151_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 587.0
TH2_k127_3623151_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 464.0
TH2_k127_3623151_2 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 327.0
TH2_k127_3623151_3 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000319 225.0
TH2_k127_3645845_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 1.833e-279 868.0
TH2_k127_3645845_1 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000000001442 184.0
TH2_k127_3645845_2 Thioredoxin-like - - - 0.0000000000000000000000000000000004291 138.0
TH2_k127_3650738_0 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 397.0
TH2_k127_3650738_1 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006257 291.0
TH2_k127_3650738_2 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.0000000000000000000004061 97.0
TH2_k127_3663854_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009989 254.0
TH2_k127_3663854_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000003539 232.0
TH2_k127_3663854_2 aminoacyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000001046 68.0
TH2_k127_3670162_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 310.0
TH2_k127_3670162_1 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 275.0
TH2_k127_3670162_2 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000008089 240.0
TH2_k127_3687144_0 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000001198 225.0
TH2_k127_3687144_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000009809 200.0
TH2_k127_3687144_2 Peptidase family U32 C-terminal domain K08303 - - 0.00000000000000000000000000000000000000000000000001855 182.0
TH2_k127_3687144_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000007779 66.0
TH2_k127_3698114_0 PFAM aminotransferase, class I K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 371.0
TH2_k127_3698114_1 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.00000000000004946 73.0
TH2_k127_3705963_0 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 586.0
TH2_k127_3705963_1 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 347.0
TH2_k127_3705963_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 336.0
TH2_k127_3705963_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 314.0
TH2_k127_3705963_4 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000004884 229.0
TH2_k127_3705963_5 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000001746 194.0
TH2_k127_3744421_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 4.582e-194 615.0
TH2_k127_3744421_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 370.0
TH2_k127_3744421_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 319.0
TH2_k127_3744421_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000002588 175.0
TH2_k127_3744421_4 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000000000000000007071 166.0
TH2_k127_3744421_5 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000007996 124.0
TH2_k127_3765927_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 374.0
TH2_k127_3765927_1 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000002941 231.0
TH2_k127_3765927_2 oxidoreductase gamma subunit K00177 - 1.2.7.3 0.00000000000000000000000000000000000002613 151.0
TH2_k127_3765927_3 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000008864 48.0
TH2_k127_3787391_0 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 494.0
TH2_k127_3787391_1 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000003677 248.0
TH2_k127_3787391_2 - - - - 0.0000000000000000000000000000000000000000000000000000000953 206.0
TH2_k127_3787391_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000004625 165.0
TH2_k127_3787391_4 - - - - 0.000000005786 59.0
TH2_k127_3788217_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 346.0
TH2_k127_3788217_1 family 5 - - - 0.00000000000000000000000000000000000000000000000000000005576 207.0
TH2_k127_378882_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.197e-194 614.0
TH2_k127_378882_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000001201 246.0
TH2_k127_378882_2 Phosphonate ABC transporter, periplasmic K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000001001 241.0
TH2_k127_378882_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000003536 225.0
TH2_k127_378882_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000001525 128.0
TH2_k127_3813280_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 385.0
TH2_k127_3813280_1 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 345.0
TH2_k127_3813280_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000003485 153.0
TH2_k127_3817621_0 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000009025 151.0
TH2_k127_3817621_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000006507 97.0
TH2_k127_3817621_2 Protein of unknown function (DUF2442) - - - 0.0000002634 53.0
TH2_k127_3837465_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 9.664e-211 660.0
TH2_k127_3837465_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000002439 171.0
TH2_k127_3839944_0 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002219 271.0
TH2_k127_3839944_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004012 251.0
TH2_k127_3839944_2 Protein of unknown function (DUF3108) - - - 0.00000000000000002774 87.0
TH2_k127_3852994_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 396.0
TH2_k127_3852994_1 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 332.0
TH2_k127_3852994_2 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 314.0
TH2_k127_3862817_0 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000136 250.0
TH2_k127_3862817_1 domain protein - - - 0.00000000000002354 79.0
TH2_k127_3867714_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 478.0
TH2_k127_3867714_1 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000104 203.0
TH2_k127_3867714_2 - - - - 0.0000000000000000000000000001367 118.0
TH2_k127_3867714_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000002209 62.0
TH2_k127_3921642_0 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 357.0
TH2_k127_3921642_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000006342 201.0
TH2_k127_3921642_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000304 61.0
TH2_k127_3971130_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 324.0
TH2_k127_3971130_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 331.0
TH2_k127_3971130_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000002137 149.0
TH2_k127_3974671_0 TraK protein K12066 - - 0.000000000000000000000000000000000000000000000000000000000000000003617 236.0
TH2_k127_3974671_1 TraE protein K12067 - - 0.000000000000000000000000000000000002818 144.0
TH2_k127_3974671_2 PFAM TraB pilus assembly family protein K12065 - - 0.000001625 53.0
TH2_k127_4019945_0 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 551.0
TH2_k127_4019945_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 291.0
TH2_k127_4019945_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000001387 197.0
TH2_k127_4019945_3 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000001133 136.0
TH2_k127_4019945_4 Transcriptional regulator K02529 - - 0.000000000000000005331 91.0
TH2_k127_4033155_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 294.0
TH2_k127_4033155_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000003891 251.0
TH2_k127_4033155_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000001525 165.0
TH2_k127_4044509_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 447.0
TH2_k127_4044509_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 370.0
TH2_k127_4044509_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 341.0
TH2_k127_4044509_3 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000002732 205.0
TH2_k127_4044509_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000003162 145.0
TH2_k127_4044509_5 protein complex oligomerization - - - 0.000000000000000000000000000002831 126.0
TH2_k127_4044509_6 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000000004718 115.0
TH2_k127_4044509_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000003158 72.0
TH2_k127_4044509_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000006864 51.0
TH2_k127_4060947_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 344.0
TH2_k127_4060947_1 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.000000000000000000000000000000000000000000000000000264 194.0
TH2_k127_4060947_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.000000005777 59.0
TH2_k127_4096003_0 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 295.0
TH2_k127_4096003_1 pfam ammecr1 K06990,K09141 - - 0.00000000000000000000000000001064 119.0
TH2_k127_4096003_2 heat shock protein binding - - - 0.0000000000000000008113 100.0
TH2_k127_411250_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 571.0
TH2_k127_411250_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 377.0
TH2_k127_411250_2 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000005556 125.0
TH2_k127_4159584_0 WHG domain - - - 0.000000000000000000000000000000000000000000000000000002457 197.0
TH2_k127_4159584_1 FMN reductase (NADPH) activity - - - 0.000000000000000000000000000000000000000000000000000003365 198.0
TH2_k127_4159584_2 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000037 190.0
TH2_k127_4159584_3 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000006519 177.0
TH2_k127_4173033_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1247.0
TH2_k127_4173033_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 328.0
TH2_k127_4182359_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 603.0
TH2_k127_4182359_1 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 379.0
TH2_k127_4182359_3 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000000009275 103.0
TH2_k127_4182359_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000001486 106.0
TH2_k127_4182359_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000003074 100.0
TH2_k127_4203776_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 416.0
TH2_k127_4203776_1 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 301.0
TH2_k127_4203776_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000004715 259.0
TH2_k127_4203776_3 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000002868 236.0
TH2_k127_4203776_4 cAMP biosynthetic process - - - 0.00000002109 67.0
TH2_k127_4209379_0 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 392.0
TH2_k127_4209379_1 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 301.0
TH2_k127_4209379_2 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000001797 224.0
TH2_k127_4237529_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 304.0
TH2_k127_4237529_1 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 294.0
TH2_k127_4237529_2 - - - - 0.00000000000000000000000009721 108.0
TH2_k127_4253109_0 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 548.0
TH2_k127_4253109_1 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 426.0
TH2_k127_4253109_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 319.0
TH2_k127_4253109_3 - - - - 0.00000000000000000000000001591 116.0
TH2_k127_4260750_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 319.0
TH2_k127_4260750_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 309.0
TH2_k127_4260750_2 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006635 284.0
TH2_k127_4260750_3 Methyltransferase small domain K07461,K15460 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 0.000000000000000008685 85.0
TH2_k127_4285112_0 protein secretion K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000009722 231.0
TH2_k127_4285112_1 Surface antigen K07277 - - 0.00000000000000000000005784 114.0
TH2_k127_4351210_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1197.0
TH2_k127_4351210_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001909 130.0
TH2_k127_4351210_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.000000000000000000000000000001558 121.0
TH2_k127_4370524_0 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 360.0
TH2_k127_4370524_1 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000005263 230.0
TH2_k127_4370524_2 Chemotaxis phosphatase CheX - - - 0.00000000000000000000000000000000000000000000000000003763 198.0
TH2_k127_4370524_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000105 164.0
TH2_k127_4370524_4 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000002057 147.0
TH2_k127_4370640_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 480.0
TH2_k127_4370640_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000002615 267.0
TH2_k127_4370640_2 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002184 234.0
TH2_k127_4370640_3 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000002475 231.0
TH2_k127_4370640_4 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000401 187.0
TH2_k127_4370640_5 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000002251 146.0
TH2_k127_4370640_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000002421 129.0
TH2_k127_4371604_0 cation transport ATPase K17686 - 3.6.3.54 1.459e-224 705.0
TH2_k127_4371604_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 393.0
TH2_k127_4371604_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000004216 201.0
TH2_k127_4372733_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 415.0
TH2_k127_4372733_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004044 288.0
TH2_k127_4372733_2 phosphorelay sensor kinase activity K03320,K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002911 279.0
TH2_k127_4372733_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000002149 196.0
TH2_k127_4382851_0 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 330.0
TH2_k127_4382851_1 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 307.0
TH2_k127_4382851_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000002112 208.0
TH2_k127_4382851_3 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000005969 114.0
TH2_k127_4382851_4 transposase K07497 - - 0.000000000000001053 79.0
TH2_k127_4382851_5 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000001154 60.0
TH2_k127_4384182_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 511.0
TH2_k127_4384182_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 497.0
TH2_k127_4384182_10 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000001667 112.0
TH2_k127_4384182_11 - - - - 0.00000000000000000000005244 99.0
TH2_k127_4384182_12 - - - - 0.000000000000000006878 85.0
TH2_k127_4384182_13 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000000008309 80.0
TH2_k127_4384182_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 422.0
TH2_k127_4384182_3 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 333.0
TH2_k127_4384182_4 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 327.0
TH2_k127_4384182_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001333 268.0
TH2_k127_4384182_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000002961 256.0
TH2_k127_4384182_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000105 200.0
TH2_k127_4384182_8 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000005125 154.0
TH2_k127_4384182_9 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000001359 108.0
TH2_k127_4400803_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 355.0
TH2_k127_4400803_1 PFAM HhH-GPD family protein K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 289.0
TH2_k127_4400803_2 DNA alkylation repair protein - - - 0.0000000000000000000000006107 108.0
TH2_k127_4409383_0 Nitroreductase - - - 4.46e-204 651.0
TH2_k127_4409383_1 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 597.0
TH2_k127_4409383_2 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 553.0
TH2_k127_4409383_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 413.0
TH2_k127_4409383_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 395.0
TH2_k127_4409383_5 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 349.0
TH2_k127_4409383_6 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000002046 118.0
TH2_k127_4425199_0 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 367.0
TH2_k127_4425199_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 334.0
TH2_k127_4425199_2 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.0000000000000000000000000000000000000000000000000008046 189.0
TH2_k127_4425199_3 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000004246 180.0
TH2_k127_4428484_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 604.0
TH2_k127_4428484_1 B3/4 domain K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 604.0
TH2_k127_4428484_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 459.0
TH2_k127_4428484_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000762 159.0
TH2_k127_4428484_4 Translation initiation factor IF-3, C-terminal domain K02520 - - 0.0000000000000000000000000000001185 126.0
TH2_k127_4428484_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000002902 88.0
TH2_k127_4450475_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000009354 210.0
TH2_k127_4450475_1 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000000000000000006506 158.0
TH2_k127_4450475_2 - - - - 0.000000000000000000000000000003588 126.0
TH2_k127_4450475_3 TIGRFAM 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008675,GO:0008700,GO:0008948,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0106009 4.1.2.14,4.1.3.42 0.000000000000000009392 83.0
TH2_k127_4483697_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 8.432e-237 746.0
TH2_k127_4483697_1 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 527.0
TH2_k127_4483697_2 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000000000000000000002808 158.0
TH2_k127_4483697_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000002056 130.0
TH2_k127_4507143_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 434.0
TH2_k127_4507143_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 432.0
TH2_k127_4507143_2 UTRA K03710 - - 0.0000957 46.0
TH2_k127_4535077_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.426e-233 730.0
TH2_k127_4535077_1 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000004956 234.0
TH2_k127_4535077_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000005947 224.0
TH2_k127_4535077_3 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000005474 188.0
TH2_k127_4535077_4 - - - - 0.0000000000000000000000000000000000000001905 155.0
TH2_k127_4535077_5 PFAM filamentation induced by cAMP protein Fic - - - 0.00000000000000000000000186 106.0
TH2_k127_4535077_6 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.000000000000000001033 87.0
TH2_k127_4535077_7 AhpC/TSA family K03386 - 1.11.1.15 0.000000000000000004814 85.0
TH2_k127_4563337_0 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 452.0
TH2_k127_4563337_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 409.0
TH2_k127_4563337_2 Protein of unknown function (DUF465) K09794 - - 0.000000000000000004221 86.0
TH2_k127_4596047_0 Sigma-54 interaction domain K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 437.0
TH2_k127_4596047_1 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 335.0
TH2_k127_4596047_2 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000003948 245.0
TH2_k127_4596047_3 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000000000000003206 198.0
TH2_k127_4596047_4 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000004022 163.0
TH2_k127_4596047_5 OsmC-like protein - - - 0.00000000000000002158 87.0
TH2_k127_4596047_6 - K07092 - - 0.0009685 48.0
TH2_k127_4596322_0 - - - - 9.199e-215 678.0
TH2_k127_4596322_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000003649 84.0
TH2_k127_4597643_0 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 428.0
TH2_k127_4597643_1 Signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 361.0
TH2_k127_4597643_2 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 294.0
TH2_k127_4597643_3 TIGRFAM Formate dehydrogenase, gamma subunit K00127 - - 0.0000000000000003361 83.0
TH2_k127_4620068_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000001987 245.0
TH2_k127_4620068_1 COG4464 Capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.0000000000000000413 82.0
TH2_k127_4620068_2 acr, cog1430 K09005 - - 0.000001985 61.0
TH2_k127_462778_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1195.0
TH2_k127_462778_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001375 275.0
TH2_k127_462778_2 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000004132 198.0
TH2_k127_462778_3 transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000001052 180.0
TH2_k127_462778_4 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.0000000000000000000000000000000000000000003739 163.0
TH2_k127_4649767_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 6.678e-210 657.0
TH2_k127_4649767_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000005363 215.0
TH2_k127_4649767_2 Male sterility protein K00091 - 1.1.1.219 0.0000000000000000000000126 106.0
TH2_k127_4711970_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 466.0
TH2_k127_4711970_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 404.0
TH2_k127_4711970_2 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000000000008425 165.0
TH2_k127_4717327_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000005812 200.0
TH2_k127_4717327_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000002318 163.0
TH2_k127_4717327_2 response to copper ion - - - 0.000000000000000000000000012 121.0
TH2_k127_4722236_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.226e-199 635.0
TH2_k127_4722236_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 306.0
TH2_k127_4722236_2 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000001301 147.0
TH2_k127_4761332_0 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000223 269.0
TH2_k127_4761332_1 ferredoxin-thioredoxin reductase activity - - - 0.000000000000000000000000000000000000000009901 155.0
TH2_k127_4761332_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.0000000000000000000002 100.0
TH2_k127_4761332_3 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000008475 96.0
TH2_k127_4761332_4 STAS domain K04749 - - 0.000000000000000002085 89.0
TH2_k127_4761332_6 - - - - 0.000000008568 62.0
TH2_k127_478288_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 472.0
TH2_k127_478288_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 388.0
TH2_k127_478288_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000002049 195.0
TH2_k127_478288_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001137 167.0
TH2_k127_478288_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000007499 118.0
TH2_k127_4783353_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.266e-283 885.0
TH2_k127_4783353_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 302.0
TH2_k127_4783353_2 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000001209 230.0
TH2_k127_4783353_3 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000001773 128.0
TH2_k127_4786303_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.028e-275 859.0
TH2_k127_4786303_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000001734 204.0
TH2_k127_4786303_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000001698 87.0
TH2_k127_4786303_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000004809 71.0
TH2_k127_483436_0 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 341.0
TH2_k127_483436_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 297.0
TH2_k127_483436_2 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000001677 228.0
TH2_k127_483436_3 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000001627 179.0
TH2_k127_483436_4 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000007101 179.0
TH2_k127_4842156_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000146 181.0
TH2_k127_4842156_1 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000008432 100.0
TH2_k127_4842156_2 - - - - 0.00000000000000657 81.0
TH2_k127_4857239_0 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007452 282.0
TH2_k127_4857239_1 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000003648 243.0
TH2_k127_4857239_2 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000003695 192.0
TH2_k127_4857239_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000003887 146.0
TH2_k127_4866647_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 8.872e-226 705.0
TH2_k127_4866647_1 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000004323 190.0
TH2_k127_4899005_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000002743 186.0
TH2_k127_4899005_1 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000000004397 150.0
TH2_k127_4899005_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000005038 139.0
TH2_k127_4899005_3 Fumarate hydratase K01677 - 4.2.1.2 0.000000006356 57.0
TH2_k127_4903278_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 568.0
TH2_k127_4903278_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 447.0
TH2_k127_4903278_2 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000004085 81.0
TH2_k127_4907416_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 455.0
TH2_k127_4907416_1 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 327.0
TH2_k127_4907416_2 Sulfatase-modifying factor enzyme 1 - - - 0.0005064 46.0
TH2_k127_4926738_0 Histidine kinase K07642,K18143 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 377.0
TH2_k127_4926738_1 VanZ like family - - - 0.00000000000000000000000000000000000000000000007078 173.0
TH2_k127_4926738_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000001792 149.0
TH2_k127_4926738_3 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000001112 122.0
TH2_k127_4926738_4 phosphorelay signal transduction system - - - 0.000000000000006426 74.0
TH2_k127_4926738_5 - - - - 0.0000001379 58.0
TH2_k127_494317_0 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 419.0
TH2_k127_494317_1 Pfam:TPM K08988 - - 0.000000000000000000000000000000000000000000000000000000002441 207.0
TH2_k127_494317_2 TPM domain K06872 - - 0.0000003244 56.0
TH2_k127_4947472_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 426.0
TH2_k127_4947472_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004036 278.0
TH2_k127_496738_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 307.0
TH2_k127_496738_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006355 249.0
TH2_k127_496738_2 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000004653 113.0
TH2_k127_496738_3 Protein of unknown function (DUF1622) - - - 0.00000000000000000000001203 104.0
TH2_k127_496738_4 - - - - 0.000000000379 63.0
TH2_k127_4976007_0 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 312.0
TH2_k127_4976007_1 cheY-homologous receiver domain - - - 0.000006351 53.0
TH2_k127_4986630_0 PFAM multicopper oxidase type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 419.0
TH2_k127_4986630_1 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 335.0
TH2_k127_4986630_2 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000006287 243.0
TH2_k127_4986630_3 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001193 224.0
TH2_k127_4986630_4 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000001795 217.0
TH2_k127_4986630_5 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000006718 204.0
TH2_k127_4986630_6 - - - - 0.00000000000000000001524 99.0
TH2_k127_4986630_7 - - - - 0.0002478 46.0
TH2_k127_4986943_0 Fe-S-cluster-containing hydrogenase K08358 - - 0.000000000000000000000000000001648 128.0
TH2_k127_4986943_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000002117 100.0
TH2_k127_4986943_2 Nitrate reductase delta subunit - - - 0.0000001709 61.0
TH2_k127_5015109_0 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 342.0
TH2_k127_5015109_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000316 212.0
TH2_k127_5061298_0 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 392.0
TH2_k127_5061298_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006016 287.0
TH2_k127_5062064_0 Diguanylate cyclase K21084 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004529 299.0
TH2_k127_5062064_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000001328 216.0
TH2_k127_5062064_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000001009 163.0
TH2_k127_5063956_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 489.0
TH2_k127_5063956_1 PFAM SufBD protein K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 334.0
TH2_k127_5063956_2 PFAM ABC transporter related K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000007445 226.0
TH2_k127_5063956_3 low molecular weight K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000131 166.0
TH2_k127_5063956_4 heat shock protein binding K05516 - - 0.000000009813 66.0
TH2_k127_5063956_5 GRIP domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005829,GO:0006810,GO:0006892,GO:0006893,GO:0006950,GO:0008104,GO:0008150,GO:0009987,GO:0012505,GO:0015031,GO:0015833,GO:0016192,GO:0033036,GO:0033554,GO:0034613,GO:0034976,GO:0042886,GO:0043001,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0048193,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051716,GO:0061951,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0072659,GO:0090150,GO:0098876,GO:1990778 - 0.00004474 57.0
TH2_k127_5095314_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1288.0
TH2_k127_5095314_1 Domain of unknown function (DUF4126) - - - 0.00005038 53.0
TH2_k127_5135916_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 342.0
TH2_k127_5135916_1 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 291.0
TH2_k127_5135916_2 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000001711 139.0
TH2_k127_5135916_3 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000003979 145.0
TH2_k127_5135916_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000006756 61.0
TH2_k127_5192982_0 Aconitase C-terminal domain K01681 - 4.2.1.3 9.639e-221 692.0
TH2_k127_5192982_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 536.0
TH2_k127_5192982_2 Ecdysteroid kinase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 460.0
TH2_k127_5192982_3 - - - - 0.00000000000000006846 87.0
TH2_k127_5195598_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 396.0
TH2_k127_5195598_1 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002033 264.0
TH2_k127_5195598_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006297 244.0
TH2_k127_5195598_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000003299 205.0
TH2_k127_5195598_4 phosphatidate phosphatase activity - - - 0.0000000000000000000000000000000236 128.0
TH2_k127_5195598_5 Belongs to the UPF0235 family K09131 - - 0.000000000000003877 79.0
TH2_k127_5196303_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 510.0
TH2_k127_5196303_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000003205 201.0
TH2_k127_5196303_2 DnaJ molecular chaperone homology domain K05516 - - 0.00000000001119 76.0
TH2_k127_5216782_0 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 5.663e-212 663.0
TH2_k127_5216782_1 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 597.0
TH2_k127_5216782_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 350.0
TH2_k127_5216782_3 Tetratricopeptide repeat K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002823 254.0
TH2_k127_5216782_4 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000001954 181.0
TH2_k127_5216782_5 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000003596 175.0
TH2_k127_5216782_6 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000006709 147.0
TH2_k127_5216782_8 peptidyl-tyrosine sulfation - - - 0.000000000002519 76.0
TH2_k127_5222577_0 Rnf-Nqr subunit, membrane protein K03613 - - 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
TH2_k127_5222577_1 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000007895 190.0
TH2_k127_5222577_2 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000195 186.0
TH2_k127_5222577_3 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000004796 110.0
TH2_k127_5279166_0 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 325.0
TH2_k127_5279166_1 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000004099 107.0
TH2_k127_5279166_2 toxin-antitoxin pair type II binding - - - 0.000000001752 59.0
TH2_k127_5337070_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 523.0
TH2_k127_5337070_1 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 317.0
TH2_k127_5337070_2 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 289.0
TH2_k127_5337070_3 Two component signalling adaptor domain K03408 - - 0.000000000000000000093 98.0
TH2_k127_5347035_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 593.0
TH2_k127_5347035_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000002001 235.0
TH2_k127_5347035_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000001852 222.0
TH2_k127_5347035_3 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000000000197 123.0
TH2_k127_5347035_4 Predicted RNA-binding protein - - - 0.000000000000000002917 87.0
TH2_k127_5347035_5 Ribosomal RNA adenine dimethylase - - - 0.0000001939 60.0
TH2_k127_5364627_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 602.0
TH2_k127_5364627_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000002889 241.0
TH2_k127_5364627_2 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000161 232.0
TH2_k127_5364627_3 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000006118 228.0
TH2_k127_5388938_0 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 514.0
TH2_k127_5388938_1 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 493.0
TH2_k127_5388938_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 437.0
TH2_k127_5388938_3 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 327.0
TH2_k127_5388938_4 - - - - 0.000000000001245 73.0
TH2_k127_5388938_5 malonyl CoA-acyl carrier protein transacylase K00645,K15327 - 2.3.1.39 0.0000006066 51.0
TH2_k127_5411100_0 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 589.0
TH2_k127_5411100_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 334.0
TH2_k127_5411100_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009915 300.0
TH2_k127_5437545_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001606 246.0
TH2_k127_5437545_1 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000005589 149.0
TH2_k127_5437545_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000006465 103.0
TH2_k127_5479918_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 438.0
TH2_k127_5479918_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 401.0
TH2_k127_5479918_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000001236 92.0
TH2_k127_5483799_0 COG0058 Glucan phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 432.0
TH2_k127_5483799_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 322.0
TH2_k127_5497156_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 527.0
TH2_k127_5497156_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 434.0
TH2_k127_5497156_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 405.0
TH2_k127_5497156_3 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 395.0
TH2_k127_5497156_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 339.0
TH2_k127_5497156_5 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000005654 265.0
TH2_k127_5497156_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000009773 206.0
TH2_k127_5501040_0 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 417.0
TH2_k127_5501040_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 379.0
TH2_k127_5501040_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000006512 132.0
TH2_k127_5501040_3 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000001047 124.0
TH2_k127_5510759_0 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000004645 148.0
TH2_k127_5510759_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000005963 141.0
TH2_k127_5510759_2 Phospholipid methyltransferase - - - 0.00000000000000001923 90.0
TH2_k127_5510759_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000001171 61.0
TH2_k127_55321_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005914 442.0
TH2_k127_55321_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 438.0
TH2_k127_55321_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000004195 234.0
TH2_k127_5556675_0 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 461.0
TH2_k127_5556675_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 302.0
TH2_k127_5556675_2 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000000000000000001176 177.0
TH2_k127_5556675_3 GYD domain - - - 0.000000000000000000000000000000000000005198 147.0
TH2_k127_5556675_4 Putative regulatory protein - - - 0.000001858 51.0
TH2_k127_5556675_5 Outer membrane lipoprotein Slp family K07285 - - 0.00000698 50.0
TH2_k127_5582061_0 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 363.0
TH2_k127_5582061_1 Cation transporter/ATPase, N-terminus - - - 0.000000000000000000000000000002044 122.0
TH2_k127_5582061_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000008866 78.0
TH2_k127_5620463_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 471.0
TH2_k127_5620463_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 291.0
TH2_k127_5669424_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.639e-247 772.0
TH2_k127_5669424_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 4.324e-206 652.0
TH2_k127_5669424_10 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000005282 147.0
TH2_k127_5669424_11 peptidyl-tyrosine sulfation - - - 0.00000000003684 76.0
TH2_k127_5669424_12 Sulfurtransferase TusA - - - 0.00000006228 54.0
TH2_k127_5669424_13 HlyD family secretion protein K03585 - - 0.00005303 47.0
TH2_k127_5669424_14 peroxiredoxin activity K01607 - 4.1.1.44 0.0005123 43.0
TH2_k127_5669424_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 434.0
TH2_k127_5669424_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 359.0
TH2_k127_5669424_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 304.0
TH2_k127_5669424_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000006609 254.0
TH2_k127_5669424_6 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000065 211.0
TH2_k127_5669424_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000009758 183.0
TH2_k127_5669424_8 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000005587 171.0
TH2_k127_5669424_9 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000005088 168.0
TH2_k127_5672740_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 524.0
TH2_k127_5672740_1 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 480.0
TH2_k127_5672740_2 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 449.0
TH2_k127_5672740_3 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 336.0
TH2_k127_5672740_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009279 282.0
TH2_k127_5672740_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000001045 221.0
TH2_k127_5672740_6 MgtC family K07507 - - 0.00000000000000000000000000000000000000007855 162.0
TH2_k127_5672740_7 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000003354 63.0
TH2_k127_5698417_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 6.264e-202 638.0
TH2_k127_5698417_1 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 320.0
TH2_k127_5698417_2 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000005035 195.0
TH2_k127_5698417_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000001536 53.0
TH2_k127_5699359_0 ATP-grasp domain K01955 - 6.3.5.5 0.0 1724.0
TH2_k127_5699359_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 353.0
TH2_k127_5699359_11 Response regulator, receiver - - - 0.00003242 49.0
TH2_k127_5699359_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 338.0
TH2_k127_5699359_3 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 306.0
TH2_k127_5699359_4 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001373 284.0
TH2_k127_5699359_5 DEAD-like helicases superfamily K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000001362 244.0
TH2_k127_5699359_6 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000881 224.0
TH2_k127_5699359_7 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000006209 181.0
TH2_k127_5699359_8 Putative regulatory protein - - - 0.00000000000000000001288 94.0
TH2_k127_5707485_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007633 458.0
TH2_k127_5707485_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 447.0
TH2_k127_5757757_0 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 389.0
TH2_k127_5757757_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 357.0
TH2_k127_5757757_2 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 331.0
TH2_k127_5757757_3 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000009681 151.0
TH2_k127_5761606_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1278.0
TH2_k127_5761606_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 616.0
TH2_k127_5761606_2 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 293.0
TH2_k127_5761606_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000001045 242.0
TH2_k127_5761606_4 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000001923 171.0
TH2_k127_5772819_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.043e-291 905.0
TH2_k127_5772819_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 6.489e-255 791.0
TH2_k127_5772819_10 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000006652 202.0
TH2_k127_5772819_11 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000923 128.0
TH2_k127_5772819_12 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.0000000000000000001733 89.0
TH2_k127_5772819_13 Sporulation and spore germination - - - 0.000000000000000004328 91.0
TH2_k127_5772819_15 Cell Wall K01448 - 3.5.1.28 0.000000000000342 81.0
TH2_k127_5772819_16 Cbb3-type cytochrome oxidase component FixQ - - - 0.000001105 51.0
TH2_k127_5772819_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 6.22e-235 746.0
TH2_k127_5772819_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 408.0
TH2_k127_5772819_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 358.0
TH2_k127_5772819_5 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 347.0
TH2_k127_5772819_6 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 342.0
TH2_k127_5772819_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 311.0
TH2_k127_5772819_8 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001612 246.0
TH2_k127_5772819_9 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000001213 239.0
TH2_k127_5799678_0 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000009698 198.0
TH2_k127_5799678_1 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000001918 174.0
TH2_k127_582372_0 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 355.0
TH2_k127_582372_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 291.0
TH2_k127_582372_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000006634 149.0
TH2_k127_582372_3 Cytochrome c554 and c-prime - - - 0.00000000000000001093 85.0
TH2_k127_5825603_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 507.0
TH2_k127_5825603_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 484.0
TH2_k127_5852942_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000008101 191.0
TH2_k127_5852942_1 Oxidoreductase NAD-binding domain K02823 - - 0.000000000000000000000000000000000000000000000003643 183.0
TH2_k127_5852942_2 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000001173 113.0
TH2_k127_5862925_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 385.0
TH2_k127_5862925_1 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000003774 139.0
TH2_k127_5862925_2 Transcriptional regulator K13640 - - 0.00000000000000000000007063 100.0
TH2_k127_5868768_0 Methyltransferase type 11 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 413.0
TH2_k127_5868768_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000004012 224.0
TH2_k127_5868768_2 Psort location CytoplasmicMembrane, score K01990,K09691,K09693 - 3.6.3.40 0.0000000002256 72.0
TH2_k127_5868819_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 318.0
TH2_k127_5868819_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000003153 93.0
TH2_k127_5880874_0 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000001968 224.0
TH2_k127_5880874_1 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000000000000000000000004911 202.0
TH2_k127_5880874_2 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000000007947 190.0
TH2_k127_5880874_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000003604 173.0
TH2_k127_5880874_4 PFAM thioesterase superfamily K02614 - - 0.0000000000000001583 84.0
TH2_k127_5880874_5 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000001748 80.0
TH2_k127_5929411_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 557.0
TH2_k127_5929411_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000002875 259.0
TH2_k127_5929411_2 - - - - 0.000393 48.0
TH2_k127_5973667_0 - K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 420.0
TH2_k127_5973667_1 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 361.0
TH2_k127_5973667_2 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000001054 141.0
TH2_k127_5973667_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000005929 133.0
TH2_k127_5973667_4 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000611 76.0
TH2_k127_5973667_5 Universal stress protein family - - - 0.000000004256 66.0
TH2_k127_5990831_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 526.0
TH2_k127_5990831_1 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001146 251.0
TH2_k127_6004526_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 7.515e-250 785.0
TH2_k127_6004526_1 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 362.0
TH2_k127_6004526_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000001229 165.0
TH2_k127_6004526_3 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000002057 73.0
TH2_k127_604022_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 330.0
TH2_k127_604022_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000009053 153.0
TH2_k127_604022_2 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000000004443 139.0
TH2_k127_6042063_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 556.0
TH2_k127_6042063_1 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 398.0
TH2_k127_6042063_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000001096 157.0
TH2_k127_6042063_3 Tetratricopeptide repeat - - - 0.0000000000000000000000002709 113.0
TH2_k127_6042063_4 ATPase (AAA superfamily K07133 - - 0.00000004669 65.0
TH2_k127_6047522_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000006433 157.0
TH2_k127_6047522_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000008231 152.0
TH2_k127_6047522_2 Acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000001878 118.0
TH2_k127_6047522_3 Sulfurtransferase TusA - - - 0.0000000000000000000000001449 108.0
TH2_k127_6049201_0 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 344.0
TH2_k127_6049201_1 iron-sulfur cluster assembly - - - 0.000000000000000000000004478 102.0
TH2_k127_6049201_2 Probable molybdopterin binding domain - - - 0.000000000005926 65.0
TH2_k127_6051034_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 357.0
TH2_k127_6051034_1 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 319.0
TH2_k127_6051034_2 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007283 273.0
TH2_k127_6051034_3 SMART Cold shock protein K03704 - - 0.0000000000000000000000000007605 113.0
TH2_k127_6066703_0 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003602 274.0
TH2_k127_6066703_1 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000001731 79.0
TH2_k127_6066703_2 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000002116 70.0
TH2_k127_6069760_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.021e-225 737.0
TH2_k127_6069760_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000001163 203.0
TH2_k127_6069760_2 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000001642 140.0
TH2_k127_6069760_3 Tetratricopeptide repeat - - - 0.0000000000001395 80.0
TH2_k127_6069760_4 zinc metalloprotease K11749 - - 0.00007463 45.0
TH2_k127_611843_0 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 381.0
TH2_k127_611843_1 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000004319 216.0
TH2_k127_611843_2 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000002168 156.0
TH2_k127_611843_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000005189 136.0
TH2_k127_611843_4 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000001968 55.0
TH2_k127_6164370_0 DnaJ molecular chaperone homology domain - - - 0.0000000009656 71.0
TH2_k127_6187464_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 556.0
TH2_k127_6187464_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006748 282.0
TH2_k127_6187464_2 - - - - 0.000000000000000000000000000000000000000001394 165.0
TH2_k127_6187464_3 photosynthesis - - - 0.00000000000000000000000000000000000002339 150.0
TH2_k127_6187464_4 - - - - 0.000000000000000000000000000000004112 132.0
TH2_k127_6196571_0 cytochrome c biogenesis protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 387.0
TH2_k127_6196571_1 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 375.0
TH2_k127_6196571_2 ADP-glyceromanno-heptose 6-epimerase activity K06118 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006643,GO:0006664,GO:0006950,GO:0007154,GO:0008146,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009247,GO:0009267,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009987,GO:0009991,GO:0016036,GO:0016740,GO:0016782,GO:0019899,GO:0019904,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046467,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0101016,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.13.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 357.0
TH2_k127_6196571_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 307.0
TH2_k127_6196571_4 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000001404 206.0
TH2_k127_6196571_5 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000002072 177.0
TH2_k127_6196571_6 PIN domain - - - 0.0000000000000001174 83.0
TH2_k127_6196571_7 CopG domain protein DNA-binding domain protein - - - 0.0002564 48.0
TH2_k127_6237182_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 492.0
TH2_k127_6237182_1 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 319.0
TH2_k127_6237182_2 Pfam Anion-transporting ATPase K01551,K19171 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000001203 228.0
TH2_k127_6237182_3 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000003658 165.0
TH2_k127_6333281_0 CobB/CobQ-like glutamine amidotransferase domain K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 524.0
TH2_k127_6333281_1 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000277 229.0
TH2_k127_6340251_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.271e-217 696.0
TH2_k127_6340251_1 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 424.0
TH2_k127_6340251_2 gas vesicle protein - - - 0.000000000000000000001808 98.0
TH2_k127_6340251_3 Protein of unknown function (DUF1722) - - - 0.0000003037 53.0
TH2_k127_6357102_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080,K14082 - 2.1.1.246,2.1.1.247,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 352.0
TH2_k127_6357102_1 CbbQ/NirQ/NorQ C-terminal - - - 0.00000000000000000000000000000000000000000004809 162.0
TH2_k127_6357102_2 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000002579 166.0
TH2_k127_6387296_0 Sugar (and other) transporter K03446 - - 4.927e-233 730.0
TH2_k127_6387296_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 608.0
TH2_k127_6387296_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 510.0
TH2_k127_6387296_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 398.0
TH2_k127_6387296_4 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 396.0
TH2_k127_6387296_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 306.0
TH2_k127_6387296_6 MarC family integral membrane protein - - - 0.0000000000000000000000000000000000000000000331 167.0
TH2_k127_6387296_7 - - - - 0.0003037 48.0
TH2_k127_6434597_0 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 308.0
TH2_k127_6434597_1 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 300.0
TH2_k127_6434597_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000002568 240.0
TH2_k127_6434597_3 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000007414 128.0
TH2_k127_6434597_4 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000003052 68.0
TH2_k127_6457266_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 601.0
TH2_k127_6457266_1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 332.0
TH2_k127_648295_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 588.0
TH2_k127_648295_1 Belongs to the bacterial solute-binding protein 3 family K02030,K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 394.0
TH2_k127_648295_2 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000001223 222.0
TH2_k127_6523612_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 4.28e-258 808.0
TH2_k127_6523612_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 526.0
TH2_k127_6523612_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 472.0
TH2_k127_6523612_3 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000001097 167.0
TH2_k127_6523612_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000003405 71.0
TH2_k127_6573618_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.907e-309 955.0
TH2_k127_6573618_1 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 383.0
TH2_k127_6573618_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 337.0
TH2_k127_6573618_3 lactate metabolic process K11473,K18928 - - 0.0000000000000000000000000000000000000000000000000000000001365 218.0
TH2_k127_6573618_4 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000003702 93.0
TH2_k127_659646_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 344.0
TH2_k127_659646_1 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001006 237.0
TH2_k127_659646_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000001819 106.0
TH2_k127_659646_3 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.0000000000000000000001198 101.0
TH2_k127_659646_4 protein involved in the oxidation of intracellular sulfur K07236 - - 0.00000003487 59.0
TH2_k127_659646_5 sulfur relay protein TusB DsrH K07237 - - 0.0007114 47.0
TH2_k127_6601679_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1189.0
TH2_k127_6601679_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 368.0
TH2_k127_6601679_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000004019 271.0
TH2_k127_6601679_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000004124 244.0
TH2_k127_6601679_4 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.000000000000000000000000000009809 130.0
TH2_k127_6601679_6 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000002522 85.0
TH2_k127_6601679_7 4Fe-4S ferredoxin iron-sulfur binding domain protein K05337 - - 0.00000000000006329 73.0
TH2_k127_6614191_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 524.0
TH2_k127_6614191_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000002344 199.0
TH2_k127_6635012_0 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000562 244.0
TH2_k127_6635012_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000007336 222.0
TH2_k127_6635012_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000006733 164.0
TH2_k127_6635012_3 Glycosyltransferase, group 1 family protein - - - 0.0000000000000000000000000019 125.0
TH2_k127_6635012_4 transferase activity, transferring glycosyl groups - - - 0.000000000009157 67.0
TH2_k127_6635012_5 PFAM phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0002358 53.0
TH2_k127_6677433_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.116e-282 874.0
TH2_k127_6677433_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000002094 87.0
TH2_k127_6681755_0 von Willebrand factor (vWF) type A domain K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 292.0
TH2_k127_6681755_1 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000005296 147.0
TH2_k127_6790299_0 12 heme-binding sites - - - 0.00000000000000000000000000000000000004519 152.0
TH2_k127_6790299_1 exonuclease activity K16899 - 3.6.4.12 0.0000001659 64.0
TH2_k127_6839553_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.254e-214 670.0
TH2_k127_6839553_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 322.0
TH2_k127_6839553_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001998 281.0
TH2_k127_6839553_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000001735 200.0
TH2_k127_6839553_4 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000007281 192.0
TH2_k127_6839553_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000005946 183.0
TH2_k127_6839553_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000037 134.0
TH2_k127_6839553_7 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001722 70.0
TH2_k127_6839553_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000002142 68.0
TH2_k127_6898634_0 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000001987 212.0
TH2_k127_6898634_1 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000002862 183.0
TH2_k127_6898634_2 - - - - 0.0000000000000000000000000000000000000000002138 169.0
TH2_k127_6898634_3 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001056 108.0
TH2_k127_6898634_4 PFAM Cold-shock protein DNA-binding K03704 - - 0.00000000000000000000003689 99.0
TH2_k127_6898634_5 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00001442 49.0
TH2_k127_6925287_0 Surface antigen K07277 - - 4.339e-247 783.0
TH2_k127_6925287_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 383.0
TH2_k127_6925287_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 375.0
TH2_k127_6925287_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000001595 236.0
TH2_k127_6925287_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000004485 202.0
TH2_k127_6925287_5 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000005598 169.0
TH2_k127_6925287_6 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00000000000000000001015 99.0
TH2_k127_6925287_7 - - - - 0.0005948 42.0
TH2_k127_6953549_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.039e-212 672.0
TH2_k127_6953549_1 ribonuclease BN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 297.0
TH2_k127_6953549_2 DHH family K07462 - - 0.0000000000000000000000000002969 117.0
TH2_k127_6980507_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 606.0
TH2_k127_6980507_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000619 205.0
TH2_k127_6980507_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000002444 141.0
TH2_k127_7020591_0 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 410.0
TH2_k127_7020591_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001196 283.0
TH2_k127_7020591_2 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000008145 241.0
TH2_k127_7020591_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000001572 109.0
TH2_k127_7020591_4 4Fe-4S single cluster domain - - - 0.000000000000000001517 97.0
TH2_k127_7020591_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000186 60.0
TH2_k127_7028865_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 482.0
TH2_k127_7028865_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 334.0
TH2_k127_7028865_2 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000000004509 200.0
TH2_k127_7028865_3 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000006863 184.0
TH2_k127_7028865_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.000000000000000000000282 103.0
TH2_k127_7028865_5 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0000001465 53.0
TH2_k127_7028865_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K01448,K02519 - 3.5.1.28 0.0003474 51.0
TH2_k127_7034429_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 557.0
TH2_k127_7035034_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 591.0
TH2_k127_7035034_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 533.0
TH2_k127_7035034_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 449.0
TH2_k127_7035034_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 338.0
TH2_k127_7035034_4 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 299.0
TH2_k127_7035034_5 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000003428 225.0
TH2_k127_7035034_7 Chemotaxis phosphatase CheX - - - 0.00000000002301 69.0
TH2_k127_7048721_0 PFAM 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 368.0
TH2_k127_7048721_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000003483 124.0
TH2_k127_7049060_0 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 330.0
TH2_k127_7049060_1 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.0000000000000000000000000000000000000000000000000000000000000000001046 243.0
TH2_k127_7049060_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000002778 191.0
TH2_k127_7049060_3 Universal stress protein family - - - 0.00000000000000000000000000000000000001383 149.0
TH2_k127_7049060_4 proteolysis K03665 - - 0.0000000000000000000000000001331 121.0
TH2_k127_7049060_5 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000003676 71.0
TH2_k127_7075793_0 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 304.0
TH2_k127_7075793_1 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000001371 250.0
TH2_k127_7090836_0 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001819 248.0
TH2_k127_7090836_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000001259 124.0
TH2_k127_7090836_2 PFAM amidohydrolase - - - 0.0000000000000000000001227 110.0
TH2_k127_7090836_3 COG3086 Positive regulator of sigma E activity K03803 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000536 54.0
TH2_k127_7130445_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 306.0
TH2_k127_7130445_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000001691 247.0
TH2_k127_7130445_2 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000001706 222.0
TH2_k127_7130445_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000003996 119.0
TH2_k127_7130445_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000001222 72.0
TH2_k127_7130445_6 Universal stress protein family K07090 - - 0.0000000000002258 71.0
TH2_k127_7130445_7 PFAM CBS domain containing protein - - - 0.000000001665 59.0
TH2_k127_7163602_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 359.0
TH2_k127_7163602_1 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000006362 203.0
TH2_k127_7163602_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000003674 135.0
TH2_k127_7163602_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0001242 44.0
TH2_k127_719259_0 Psort location CytoplasmicMembrane, score K01990,K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001642 280.0
TH2_k127_719259_1 Bacterial type II and III secretion system protein K02453,K03219 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001509 267.0
TH2_k127_719259_2 PFAM phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000004826 233.0
TH2_k127_719259_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001843 211.0
TH2_k127_719259_4 ABC-2 type transporter K01992,K09690 - - 0.00000000000000000000000000000000000000000000000000000000366 208.0
TH2_k127_719259_5 Sulfatase - - - 0.000000000000008445 81.0
TH2_k127_719259_6 Psort location CytoplasmicMembrane, score K09153 - - 0.000000001719 63.0
TH2_k127_7206435_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 604.0
TH2_k127_7208929_0 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 426.0
TH2_k127_7208929_1 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 306.0
TH2_k127_7208929_2 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000000000000003273 99.0
TH2_k127_7211649_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 359.0
TH2_k127_7211649_1 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003406 276.0
TH2_k127_7223215_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000001759 246.0
TH2_k127_7223215_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000001768 157.0
TH2_k127_726718_0 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 371.0
TH2_k127_726718_1 Histidine kinase - - - 0.00003004 54.0
TH2_k127_727935_0 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000009249 218.0
TH2_k127_7287665_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 510.0
TH2_k127_7287665_1 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 383.0
TH2_k127_7287665_2 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000001913 137.0
TH2_k127_7287665_3 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000005932 118.0
TH2_k127_7287665_4 NAD+ diphosphatase activity K01515,K03426 - 3.6.1.13,3.6.1.22 0.00001374 57.0
TH2_k127_7289898_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 485.0
TH2_k127_7289898_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 301.0
TH2_k127_7289898_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003252 275.0
TH2_k127_7289898_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000002579 244.0
TH2_k127_7289898_4 DivIVA protein K04074 - - 0.000000000000000000000000000000000000000000000000000000000000000001893 229.0
TH2_k127_7289898_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000001248 159.0
TH2_k127_7289898_6 YGGT family K02221 - - 0.0000000000000000000000000000000000296 137.0
TH2_k127_7289898_7 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00003569 49.0
TH2_k127_7311102_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 524.0
TH2_k127_7311102_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 484.0
TH2_k127_7311102_10 Protein of unknown function (DUF2845) - - - 0.00000000000241 72.0
TH2_k127_7311102_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 328.0
TH2_k127_7311102_3 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001838 280.0
TH2_k127_7311102_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000008808 255.0
TH2_k127_7311102_5 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000000000000000000000001156 209.0
TH2_k127_7311102_6 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000000000003157 205.0
TH2_k127_7311102_7 electron transfer activity K02305,K08738 - - 0.000000000000000000000000000000000000000000000000000001168 197.0
TH2_k127_7311102_8 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000004233 136.0
TH2_k127_7311102_9 sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.000000000000000000007252 97.0
TH2_k127_731166_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.107e-233 731.0
TH2_k127_731166_1 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 525.0
TH2_k127_731166_2 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 450.0
TH2_k127_731166_3 Proposed homoserine kinase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000002387 203.0
TH2_k127_7322199_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 524.0
TH2_k127_7322199_1 lipoprotein localization to outer membrane K02004,K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 479.0
TH2_k127_7322199_2 lipoprotein transporter activity K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 306.0
TH2_k127_7322199_3 - - - - 0.0000000000000000000000005166 108.0
TH2_k127_7362744_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 2.447e-206 653.0
TH2_k127_7362744_1 Transport of potassium into the cell K03549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 556.0
TH2_k127_7389974_0 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006042 261.0
TH2_k127_7389974_1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000001913 250.0
TH2_k127_7389974_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000008963 240.0
TH2_k127_7389974_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000001357 221.0
TH2_k127_7389974_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000000000000000000004213 158.0
TH2_k127_7389974_5 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000006658 85.0
TH2_k127_7397794_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 288.0
TH2_k127_7397794_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000187 282.0
TH2_k127_7397794_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000001206 111.0
TH2_k127_7397794_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000009731 102.0
TH2_k127_7410285_0 Cbs domain - - - 0.0000000000000000002434 93.0
TH2_k127_7410285_1 Thioesterase K18700 - 3.1.2.29 0.0000000000000008811 79.0
TH2_k127_7410285_2 Alpha/beta hydrolase family - - - 0.0000000000001772 81.0
TH2_k127_7410285_3 Thioesterase K18700 - 3.1.2.29 0.0000001009 53.0
TH2_k127_7417938_0 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 371.0
TH2_k127_7417938_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 324.0
TH2_k127_7417938_2 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002382 283.0
TH2_k127_7417938_3 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002306 246.0
TH2_k127_7417938_4 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000001248 165.0
TH2_k127_7434147_0 Pyridine nucleotide-disulphide oxidoreductase K15022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 555.0
TH2_k127_7434147_1 2Fe-2S iron-sulfur cluster binding domain K05299 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000001285 243.0
TH2_k127_7434147_2 Diguanylate cyclase - - - 0.0000000000000001237 80.0
TH2_k127_7472903_0 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002512 263.0
TH2_k127_7472903_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001716 266.0
TH2_k127_7472903_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.000000000000000000000000000000000000000000000000009356 190.0
TH2_k127_7472903_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000001795 146.0
TH2_k127_7472903_4 NosL - - - 0.00000000006084 70.0
TH2_k127_7472903_6 lipopolysaccharide transmembrane transporter activity K03303,K07058 - - 0.0000178 56.0
TH2_k127_7474070_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 384.0
TH2_k127_7474070_1 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000001431 74.0
TH2_k127_7485672_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 4.662e-201 642.0
TH2_k127_7500527_0 COG0526, thiol-disulfide isomerase and thioredoxins K21636 - 1.1.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000025 279.0
TH2_k127_7500527_1 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000002899 136.0
TH2_k127_7505043_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000004925 139.0
TH2_k127_7505043_1 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000004805 117.0
TH2_k127_7533952_0 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 423.0
TH2_k127_7533952_1 Phosphonate ABC transporter, periplasmic K02044 - - 0.000000000000000000000000000000000000000000000000000000000003675 218.0
TH2_k127_7533952_3 PFAM ATP-binding region, ATPase domain protein - - - 0.00000009266 61.0
TH2_k127_754017_0 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 350.0
TH2_k127_754017_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 340.0
TH2_k127_754017_2 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000000005069 201.0
TH2_k127_754017_3 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000005039 173.0
TH2_k127_754017_4 nuclease activity K06218 - - 0.000000000000000000001114 96.0
TH2_k127_754017_5 - - - - 0.000000004605 60.0
TH2_k127_7549708_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 416.0
TH2_k127_7549708_1 SMART helicase c2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 364.0
TH2_k127_7549708_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001882 236.0
TH2_k127_7549708_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000008817 109.0
TH2_k127_7551097_0 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 534.0
TH2_k127_7551097_1 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 413.0
TH2_k127_7559496_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 541.0
TH2_k127_7559496_1 PFAM ABC transporter related K02003 - - 0.000000000000000000000000001874 112.0
TH2_k127_7559496_2 MacB-like periplasmic core domain K02004 - - 0.00000000000001856 73.0
TH2_k127_7624925_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 364.0
TH2_k127_7666066_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 570.0
TH2_k127_7666066_1 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 362.0
TH2_k127_7666066_10 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000009296 119.0
TH2_k127_7666066_11 DRTGG domain - - - 0.000000000000000000000000005266 117.0
TH2_k127_7666066_12 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000005058 102.0
TH2_k127_7666066_13 cyclic nucleotide-binding K01420,K21563 - - 0.0001622 48.0
TH2_k127_7666066_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 282.0
TH2_k127_7666066_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001684 205.0
TH2_k127_7666066_4 PHP-associated K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000001785 210.0
TH2_k127_7666066_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000002784 184.0
TH2_k127_7666066_6 Histidine kinase - - - 0.000000000000000000000000000000000000000001732 164.0
TH2_k127_7666066_7 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.00000000000000000000000000000000000000003707 156.0
TH2_k127_7666066_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000001783 151.0
TH2_k127_7666066_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000005289 143.0
TH2_k127_7674234_0 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 428.0
TH2_k127_7674234_1 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.0000000000000004317 79.0
TH2_k127_7674234_2 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0006531 44.0
TH2_k127_7678168_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2141.0
TH2_k127_7678168_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1095.0
TH2_k127_7678168_2 K transport systems K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 363.0
TH2_k127_7678168_3 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000009727 132.0
TH2_k127_7681723_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 296.0
TH2_k127_7681723_1 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000001571 186.0
TH2_k127_7681723_2 Cation efflux family - - - 0.000002321 50.0
TH2_k127_769503_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 2.758e-263 830.0
TH2_k127_769503_1 - - - - 0.000000003542 58.0
TH2_k127_769522_0 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 426.0
TH2_k127_769522_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 367.0
TH2_k127_769522_2 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 316.0
TH2_k127_769522_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000097 286.0
TH2_k127_769522_4 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003566 229.0
TH2_k127_769522_5 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000000000001836 194.0
TH2_k127_769522_6 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000002515 149.0
TH2_k127_769522_7 cheY-homologous receiver domain - - - 0.00007506 50.0
TH2_k127_7720281_0 - K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 384.0
TH2_k127_7720281_1 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000129 112.0
TH2_k127_7720281_2 TIGRFAM methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.0000000000000000000000002606 108.0
TH2_k127_7720281_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000002591 88.0
TH2_k127_7724374_0 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 364.0
TH2_k127_7724374_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000001147 136.0
TH2_k127_7724374_2 Sulfurtransferase TusA K04085 - - 0.00000000000000000006187 91.0
TH2_k127_7724374_3 Diguanylate cyclase - - - 0.00003223 51.0
TH2_k127_7751762_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.294e-221 692.0
TH2_k127_7751762_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 310.0
TH2_k127_7751762_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 310.0
TH2_k127_7751762_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000001428 191.0
TH2_k127_7801701_0 TPR repeat - - - 0.00000000003757 75.0
TH2_k127_7832723_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 426.0
TH2_k127_7832723_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 407.0
TH2_k127_7832723_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000139 267.0
TH2_k127_7832723_3 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000009236 181.0
TH2_k127_7832723_4 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000004681 166.0
TH2_k127_7832723_5 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000004866 90.0
TH2_k127_784430_0 TonB-dependent Receptor Plug Domain K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 550.0
TH2_k127_784430_1 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000006236 191.0
TH2_k127_784430_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.000000000000000000000000000000000000003796 154.0
TH2_k127_784430_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000001715 58.0
TH2_k127_7856661_0 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 323.0
TH2_k127_7856661_1 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000000002715 183.0
TH2_k127_7856661_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000004079 186.0
TH2_k127_7856661_3 cheY-homologous receiver domain - - - 0.00009741 54.0
TH2_k127_7857294_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 508.0
TH2_k127_7857294_1 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000008415 241.0
TH2_k127_7894219_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 412.0
TH2_k127_7894219_1 PFAM Carbamoyltransferase K00612 - - 0.00000000000000000000000000000000000000000000000000002787 192.0
TH2_k127_7894219_2 Radical SAM - - - 0.000000000000000000000000000000000008382 150.0
TH2_k127_7894219_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000001634 147.0
TH2_k127_7894219_4 FemAB family - - - 0.000000000008816 77.0
TH2_k127_7894219_5 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.0000000003584 64.0
TH2_k127_7894219_6 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00001841 53.0
TH2_k127_7894219_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00001898 56.0
TH2_k127_7894219_8 - - - - 0.00005272 48.0
TH2_k127_7894905_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 6.973e-201 633.0
TH2_k127_7894905_1 PFAM Type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 297.0
TH2_k127_7894905_2 Fructose-bisphosphate aldolase class-II - - - 0.000000000000003123 76.0
TH2_k127_7910581_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 359.0
TH2_k127_7910581_1 SMART Cold shock protein K03704 - - 0.000000000000000000000000000002636 120.0
TH2_k127_7910581_2 Stringent starvation protein B K09985 - - 0.00000000000000000000000000003509 123.0
TH2_k127_7910581_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000006944 59.0
TH2_k127_7910581_4 cheY-homologous receiver domain - - - 0.00004278 53.0
TH2_k127_7921444_0 Domains REC, sigma54 interaction, HTH8 K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 573.0
TH2_k127_7921444_1 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000001219 234.0
TH2_k127_793612_0 ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 340.0
TH2_k127_793612_1 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001006 265.0
TH2_k127_793612_2 Permease K02004 - - 0.000000000000000000000000000000000002274 155.0
TH2_k127_7941632_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006227 263.0
TH2_k127_7941632_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000001575 165.0
TH2_k127_7941632_2 - - - - 0.00000000000000000000002149 105.0
TH2_k127_7980317_0 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000001265 235.0
TH2_k127_7980317_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000003643 71.0
TH2_k127_8015310_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 474.0
TH2_k127_8015310_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000003091 137.0
TH2_k127_8015310_2 PFAM conserved K07027 - - 0.00008782 48.0
TH2_k127_8028965_0 Peptidase family M28 - - - 0.0 1140.0
TH2_k127_8028965_1 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 392.0
TH2_k127_8028965_2 Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 338.0
TH2_k127_8095624_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000311 234.0
TH2_k127_8095624_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000003844 236.0
TH2_k127_8095624_2 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.0000000000000000000000000000009116 124.0
TH2_k127_8173938_0 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 296.0
TH2_k127_8173938_1 Mo-molybdopterin cofactor metabolic process K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004918 259.0
TH2_k127_8177551_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 379.0
TH2_k127_8177551_1 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001065 275.0
TH2_k127_8177551_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000007712 179.0
TH2_k127_8187480_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.242e-310 974.0
TH2_k127_8187480_1 Threonyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000001218 165.0
TH2_k127_8187480_2 heme oxygenase (decyclizing) activity - - - 0.0000000000000000005432 90.0
TH2_k127_821163_0 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 460.0
TH2_k127_821163_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 355.0
TH2_k127_821163_2 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000009123 231.0
TH2_k127_821163_3 tRNA modification K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000000003667 224.0
TH2_k127_821163_4 Universal stress protein family - - - 0.0000000000001963 76.0
TH2_k127_821163_5 - - - - 0.0000000002382 69.0
TH2_k127_8247198_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 599.0
TH2_k127_8247198_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 436.0
TH2_k127_8247198_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000009436 207.0
TH2_k127_8247198_3 thiamine diphosphate biosynthetic process K03149,K03154 - 2.8.1.10 0.000000000000009395 75.0
TH2_k127_8247198_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000002701 67.0
TH2_k127_8307769_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 518.0
TH2_k127_8307769_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 506.0
TH2_k127_8307769_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 402.0
TH2_k127_8307769_3 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 323.0
TH2_k127_8307769_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000003712 233.0
TH2_k127_832313_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 379.0
TH2_k127_832313_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 371.0
TH2_k127_832313_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000001382 219.0
TH2_k127_832313_3 polysaccharide catabolic process K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000005017 202.0
TH2_k127_832313_4 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000008301 155.0
TH2_k127_832313_5 Cation efflux family K16264 - - 0.00000000000000000000000000000012 126.0
TH2_k127_832313_6 ABC1 family K03688 - - 0.0000000000000000000000000001473 119.0
TH2_k127_832313_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000669 78.0
TH2_k127_832557_0 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 405.0
TH2_k127_832557_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001438 252.0
TH2_k127_832557_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000001862 140.0
TH2_k127_832557_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000004519 143.0
TH2_k127_832557_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000002689 76.0
TH2_k127_8365773_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 297.0
TH2_k127_8365773_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000615 243.0
TH2_k127_8365773_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000001989 193.0
TH2_k127_8365773_3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity K03182 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 0.00000000000000000000000000000002777 126.0
TH2_k127_8365773_4 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000007665 58.0
TH2_k127_8397834_0 methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 406.0
TH2_k127_8397834_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003266 265.0
TH2_k127_8397834_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 254.0
TH2_k127_8397834_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001621 226.0
TH2_k127_8397834_4 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000006941 230.0
TH2_k127_8397834_5 protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000000002608 201.0
TH2_k127_8397834_6 MazG nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000000003096 134.0
TH2_k127_8397834_7 regulation of translation K03530 - - 0.000000000000000000000000000000001958 131.0
TH2_k127_8397834_8 Protein of unknown function (DUF3641) - - - 0.000000000000000000000008208 115.0
TH2_k127_8412318_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 432.0
TH2_k127_8412318_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 364.0
TH2_k127_8412318_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000001784 222.0
TH2_k127_8412318_3 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000005888 147.0
TH2_k127_8412318_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000002945 137.0
TH2_k127_8412318_5 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000006684 90.0
TH2_k127_8440758_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 605.0
TH2_k127_8440758_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 328.0
TH2_k127_8440758_2 Single-strand DNA-specific exonuclease, C terminal domain K07462 - - 0.00002798 48.0
TH2_k127_8443788_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 399.0
TH2_k127_8443788_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 324.0
TH2_k127_8443788_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000144 164.0
TH2_k127_8443788_11 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000001127 157.0
TH2_k127_8443788_12 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000003228 154.0
TH2_k127_8443788_13 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000002657 151.0
TH2_k127_8443788_14 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000002978 136.0
TH2_k127_8443788_15 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000002863 115.0
TH2_k127_8443788_16 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000009174 104.0
TH2_k127_8443788_17 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000002158 100.0
TH2_k127_8443788_18 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000003142 79.0
TH2_k127_8443788_19 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000002828 72.0
TH2_k127_8443788_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 293.0
TH2_k127_8443788_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 280.0
TH2_k127_8443788_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000004125 230.0
TH2_k127_8443788_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000644 232.0
TH2_k127_8443788_6 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000006751 228.0
TH2_k127_8443788_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000254 196.0
TH2_k127_8443788_8 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000006263 173.0
TH2_k127_8443788_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000009317 174.0
TH2_k127_8454420_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 443.0
TH2_k127_8454420_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 292.0
TH2_k127_8454420_2 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000002641 249.0
TH2_k127_8454420_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000006944 228.0
TH2_k127_8464853_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 597.0
TH2_k127_8464853_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000002094 249.0
TH2_k127_8464853_2 YbbR-like protein - - - 0.00000000000000000000000609 106.0
TH2_k127_8474629_0 Elongation factor SelB, winged helix K03833 - - 2.609e-208 665.0
TH2_k127_8474629_1 OsmC-like protein K07397 - - 0.000000000000002609 80.0
TH2_k127_8495493_0 phosphorelay sensor kinase activity K07708,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000000000000000000000000000000000000002431 194.0
TH2_k127_8495493_1 Putative methyltransferase - - - 0.000000000000000000000005226 116.0
TH2_k127_8511829_0 phosphate ion binding K02038,K02040 - - 0.0000000000000000000000000000000000000000000000000000003336 203.0
TH2_k127_8515699_0 AAA domain K02450,K12283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 325.0
TH2_k127_8515699_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000101 281.0
TH2_k127_8515699_2 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000008224 164.0
TH2_k127_8525697_0 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 371.0
TH2_k127_8525697_1 hyperosmotic response K04065 - - 0.000000000000007875 79.0
TH2_k127_8525697_2 GYD domain - - - 0.0000000004926 64.0
TH2_k127_8555467_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 391.0
TH2_k127_8555467_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001713 267.0
TH2_k127_8555467_2 CHASE2 K01768 - 4.6.1.1 0.0000000000000000008266 88.0
TH2_k127_8555467_3 transcriptional regulator K03892 - - 0.0000000000001589 76.0
TH2_k127_8557313_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000001078 229.0
TH2_k127_8557313_1 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000632 168.0
TH2_k127_8557313_2 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.000000000000008051 76.0
TH2_k127_8557313_3 - - - - 0.0000000000002549 72.0
TH2_k127_8557313_4 carbon dioxide binding K04653,K04654 - - 0.000007896 51.0
TH2_k127_8581802_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 572.0
TH2_k127_8581802_1 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006021 244.0
TH2_k127_8595623_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.29e-269 844.0
TH2_k127_8595623_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002409 276.0
TH2_k127_8595623_2 metallopeptidase activity K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002117 245.0
TH2_k127_8595623_3 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000002863 191.0
TH2_k127_8605044_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 518.0
TH2_k127_8605044_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000002067 156.0
TH2_k127_8605044_2 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000005067 120.0
TH2_k127_8605044_3 PFAM Fimbrial assembly K02461 - - 0.0000000001684 74.0
TH2_k127_8605044_4 Type II secretion system (T2SS), protein M subtype b - - - 0.0000000002738 68.0
TH2_k127_8633636_0 lipopolysaccharide biosynthesis K20998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 367.0
TH2_k127_8633636_1 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004336 279.0
TH2_k127_8633636_2 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001707 256.0
TH2_k127_8633636_3 polysaccharide K01991,K20987 - - 0.000000000000009754 76.0
TH2_k127_8633636_4 O-antigen ligase like membrane protein - - - 0.00000001601 61.0
TH2_k127_8635970_0 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 488.0
TH2_k127_8635970_1 Hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000612 203.0
TH2_k127_8635970_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000000000000000000000000008742 142.0
TH2_k127_8637642_0 Heat shock 70 kDa protein K04043 - - 0.0 1011.0
TH2_k127_8637642_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 441.0
TH2_k127_8637642_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000009814 170.0
TH2_k127_8637642_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000002122 155.0
TH2_k127_8637642_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000001541 148.0
TH2_k127_8638756_0 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 9.758e-298 930.0
TH2_k127_8638756_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004601 284.0
TH2_k127_8638756_2 - - - - 0.00000000000000000008732 93.0
TH2_k127_8658073_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.584e-205 656.0
TH2_k127_8658073_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 439.0
TH2_k127_8658073_2 Response regulator receiver - - - 0.00000000000000000000000186 106.0
TH2_k127_8664788_0 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 392.0
TH2_k127_8664788_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000005179 177.0
TH2_k127_8664788_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000001657 135.0
TH2_k127_8664788_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000005323 76.0
TH2_k127_8670993_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 368.0
TH2_k127_8670993_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 320.0
TH2_k127_8670993_2 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003164 279.0
TH2_k127_8670993_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000001781 205.0
TH2_k127_8670993_4 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001941 206.0
TH2_k127_8670993_5 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000008676 146.0
TH2_k127_8670993_6 Hydrogenase expression formation protein hypD K04654 - - 0.00000000000004331 72.0
TH2_k127_8692931_0 protein secretion K09800 - - 0.00000000000000000000000000000000000000000000000000000000000003913 238.0
TH2_k127_8692931_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000003893 84.0
TH2_k127_8718567_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 398.0
TH2_k127_8718567_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001941 286.0
TH2_k127_8718567_2 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000019 156.0
TH2_k127_8718567_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000003855 59.0
TH2_k127_8742097_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000009682 184.0
TH2_k127_8742097_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000003061 109.0
TH2_k127_8742097_2 Iron-sulfur cluster-binding domain - - - 0.0000000000000026 88.0
TH2_k127_8749763_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000004033 188.0
TH2_k127_8749763_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000002083 173.0
TH2_k127_8749763_2 addiction module antidote protein, HigA family K21498 - - 0.0000000000000000000000000000000000000002689 151.0
TH2_k127_8749763_3 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000000000002075 148.0
TH2_k127_8749763_4 InterPro IPR007367 - - - 0.000000000000000000000005872 106.0
TH2_k127_8767442_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 9.675e-222 706.0
TH2_k127_8767442_1 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000003248 216.0
TH2_k127_8767442_2 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.00000000000000000000000000000000000000007413 151.0
TH2_k127_878306_0 transferase activity, transferring glycosyl groups K02844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 317.0
TH2_k127_878306_1 biosynthesis glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002894 266.0
TH2_k127_878306_2 methyltransferase - - - 0.00000000000000000000000000000000001749 144.0
TH2_k127_878306_3 Glycosyltransferase - - - 0.0000000000000000002261 93.0
TH2_k127_878306_4 Spore maturation protein cgeB K06320 - - 0.000000000000001078 88.0
TH2_k127_878306_5 O-Antigen ligase - - - 0.000006399 58.0
TH2_k127_8791964_0 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000009327 237.0
TH2_k127_8791964_1 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000002566 193.0
TH2_k127_8791964_2 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000008555 126.0
TH2_k127_8791964_3 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000729 115.0
TH2_k127_8791964_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000005088 97.0
TH2_k127_8796986_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 484.0
TH2_k127_8796986_1 - - - - 0.00000000000000000000000000001079 124.0
TH2_k127_8811490_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 502.0
TH2_k127_8811490_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 407.0
TH2_k127_8811490_2 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 396.0
TH2_k127_8811490_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000001274 72.0
TH2_k127_8838719_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 4.883e-313 970.0
TH2_k127_8838719_1 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 327.0
TH2_k127_8838719_2 PFAM Glutamine amidotransferase, class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 308.0
TH2_k127_8863175_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 3.25e-220 693.0
TH2_k127_8863175_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 454.0
TH2_k127_8863175_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 350.0
TH2_k127_8863175_3 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001168 257.0
TH2_k127_8863175_4 Redoxin K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 253.0
TH2_k127_8863175_5 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007742 255.0
TH2_k127_8863175_6 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000004043 165.0
TH2_k127_8863175_7 Ion channel K10716 - - 0.000000000000000000000000000000000000001051 151.0
TH2_k127_8866338_0 Elongation factor G, domain IV K02355 - - 3.615e-310 965.0
TH2_k127_8866338_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.268e-254 803.0
TH2_k127_8866338_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000932 237.0
TH2_k127_8866338_3 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000004495 164.0
TH2_k127_8866338_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000006955 146.0
TH2_k127_8866338_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000002121 100.0
TH2_k127_8866338_6 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.0000002204 58.0
TH2_k127_8866338_7 DSBA-like thioredoxin domain - - - 0.00003488 50.0
TH2_k127_8869706_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 452.0
TH2_k127_8876814_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 308.0
TH2_k127_8876814_1 protein histidine kinase activity - - - 0.000000000000000000000001873 111.0
TH2_k127_8876814_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00005047 47.0
TH2_k127_887854_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 321.0
TH2_k127_887854_1 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 309.0
TH2_k127_887854_2 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000007544 184.0
TH2_k127_900524_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 582.0
TH2_k127_900524_1 Glutathione peroxidase - - - 0.0000000000000000000000000000000006604 136.0
TH2_k127_906297_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1360.0
TH2_k127_906297_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000004717 223.0
TH2_k127_906297_2 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000001426 144.0
TH2_k127_906297_3 Protein of unknown function (DUF3641) - - - 0.0005016 42.0
TH2_k127_91433_0 Ribonuclease E/G family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 452.0
TH2_k127_91433_1 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 286.0
TH2_k127_91433_2 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000002392 168.0
TH2_k127_91433_3 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.000000000000000000000000005388 110.0
TH2_k127_91433_4 COG1522 Transcriptional regulators - - - 0.0001461 47.0
TH2_k127_923271_0 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 350.0
TH2_k127_923271_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 343.0
TH2_k127_923271_2 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000002893 223.0
TH2_k127_923271_3 lyase activity - - - 0.00000000000000000000000000000000000000000000000000333 205.0
TH2_k127_923271_4 - - - - 0.00000000000000000000000000000000000001426 153.0
TH2_k127_923271_5 4Fe-4S binding domain - - - 0.000000000000000000000000001283 121.0
TH2_k127_932092_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 7.945e-286 887.0
TH2_k127_932092_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 443.0
TH2_k127_932092_2 2 iron, 2 sulfur cluster binding K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000004903 203.0
TH2_k127_956993_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 487.0
TH2_k127_956993_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 403.0
TH2_k127_956993_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 309.0
TH2_k127_956993_3 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000009004 183.0
TH2_k127_956993_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000001114 142.0
TH2_k127_956993_5 deoxyhypusine monooxygenase activity K05386 - - 0.0000000000000000003485 93.0
TH2_k127_957209_0 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 492.0
TH2_k127_957209_1 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 454.0
TH2_k127_957209_2 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 332.0
TH2_k127_957209_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 316.0
TH2_k127_957209_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004375 277.0
TH2_k127_968468_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1245.0
TH2_k127_968468_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000003185 210.0
TH2_k127_968468_2 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000002246 155.0