Overview

ID MAG03931
Name TH3_bin.1
Sample SMP0102
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order UBA10834
Family UBA10834
Genus UBA9653
Species
Assembly information
Completeness (%) 68.61
Contamination (%) 3.13
GC content (%) 64.0
N50 (bp) 4,722
Genome size (bp) 1,425,921

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1410

Gene name Description KEGG GOs EC E-value Score Sequence
TH3_k127_1049629_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000001638 171.0
TH3_k127_1049629_1 Proprotein convertase P-domain - - - 0.0000000000004144 78.0
TH3_k127_1049629_2 self proteolysis - - - 0.0000004565 60.0
TH3_k127_1049629_3 Double zinc ribbon - - - 0.0001528 51.0
TH3_k127_1063975_0 Lamin Tail Domain - - - 0.000000000000000000000001295 121.0
TH3_k127_116098_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 407.0
TH3_k127_116098_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 322.0
TH3_k127_116098_2 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 322.0
TH3_k127_116098_3 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 310.0
TH3_k127_116098_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
TH3_k127_116098_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002154 268.0
TH3_k127_116098_6 ribosomal protein K02921 - - 0.000447 42.0
TH3_k127_116098_7 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.000778 46.0
TH3_k127_1169653_0 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 322.0
TH3_k127_1169653_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000000000000000006357 228.0
TH3_k127_1169653_2 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000004899 204.0
TH3_k127_1263052_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 336.0
TH3_k127_1263052_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000002064 169.0
TH3_k127_1263052_2 SIS domain K08094 - 5.3.1.27 0.00000000000000000000000000000000000000005532 169.0
TH3_k127_1263052_3 PFAM UBA THIF-type NAD FAD binding protein - - - 0.0000000000000000000000000000000000114 147.0
TH3_k127_1263052_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001529 133.0
TH3_k127_1263052_5 COP9 signalosome complex subunit 5 K09613 GO:0000003,GO:0000338,GO:0000749,GO:0000754,GO:0000909,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008180,GO:0008233,GO:0008234,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0010893,GO:0016787,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019538,GO:0019783,GO:0019784,GO:0019953,GO:0022414,GO:0023051,GO:0023058,GO:0030447,GO:0030448,GO:0030582,GO:0030584,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032443,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0036211,GO:0040007,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045116,GO:0045834,GO:0045940,GO:0046889,GO:0046890,GO:0046999,GO:0048518,GO:0048522,GO:0048583,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051704,GO:0051716,GO:0061458,GO:0062012,GO:0062013,GO:0065007,GO:0070011,GO:0070452,GO:0070646,GO:0070647,GO:0070791,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0075259,GO:0080090,GO:0106118,GO:0106120,GO:0140096,GO:1901564,GO:1902930,GO:1902932,GO:2000241,GO:2000243 - 0.0000000000001637 80.0
TH3_k127_1263052_6 histone ubiquitination K10573 GO:0000151,GO:0000209,GO:0000228,GO:0000785,GO:0000790,GO:0000792,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006325,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016043,GO:0016567,GO:0016569,GO:0016570,GO:0016574,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0030163,GO:0031371,GO:0031625,GO:0031974,GO:0031981,GO:0032446,GO:0032991,GO:0033503,GO:0033554,GO:0034641,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051603,GO:0051716,GO:0061630,GO:0061659,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234 2.3.2.23 0.00000000007788 72.0
TH3_k127_1307051_0 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000001238 213.0
TH3_k127_1307051_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000003607 189.0
TH3_k127_1307051_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000006408 186.0
TH3_k127_1307051_3 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000003393 116.0
TH3_k127_1307051_4 NB-ARC domain - - - 0.00000005656 64.0
TH3_k127_132663_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 533.0
TH3_k127_132663_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004324 288.0
TH3_k127_132663_2 asparaginyl-tRNA aminoacylation K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000392 209.0
TH3_k127_132663_3 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00000000000001291 80.0
TH3_k127_1372020_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 537.0
TH3_k127_1372020_1 serine threonine protein kinase - - - 0.0000000000000000002583 100.0
TH3_k127_1378840_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 409.0
TH3_k127_1378840_1 Belongs to the peptidase S51 family - - - 0.000000000006914 69.0
TH3_k127_1385470_0 GXGXG motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 478.0
TH3_k127_1385470_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 406.0
TH3_k127_1385470_2 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000236 276.0
TH3_k127_1385470_3 SpoVT / AbrB like domain - - - 0.00000000003757 67.0
TH3_k127_1397168_0 Aminotransferase class-III K00823,K03918,K20428 - 2.6.1.19,2.6.1.33,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 302.0
TH3_k127_1500729_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000001586 194.0
TH3_k127_1503587_0 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 1.652e-210 669.0
TH3_k127_1503587_1 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 605.0
TH3_k127_1503587_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 377.0
TH3_k127_1503587_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000001239 127.0
TH3_k127_1569506_0 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000001063 226.0
TH3_k127_1569506_1 Lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000001537 177.0
TH3_k127_1599582_0 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 573.0
TH3_k127_1599582_1 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 384.0
TH3_k127_1599582_2 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 286.0
TH3_k127_1599582_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000001154 106.0
TH3_k127_1599582_4 PFAM Acetyltransferase (GNAT) family - - - 0.0000000009441 69.0
TH3_k127_1606882_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000025 290.0
TH3_k127_1606882_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000001577 205.0
TH3_k127_1606882_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000000001337 171.0
TH3_k127_1606882_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.00000000000000000000000000002679 117.0
TH3_k127_1606882_4 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000003639 95.0
TH3_k127_1633259_0 ABC transporter K00400,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 355.0
TH3_k127_1633259_1 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000004171 235.0
TH3_k127_1633259_2 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000001581 192.0
TH3_k127_1633259_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000001394 172.0
TH3_k127_1633259_4 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000003583 145.0
TH3_k127_1633259_5 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000002852 106.0
TH3_k127_1633259_6 serine threonine protein kinase - - - 0.000000000000000001109 95.0
TH3_k127_1633259_7 - - - - 0.00000001108 62.0
TH3_k127_1641049_0 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 364.0
TH3_k127_1641049_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000001404 237.0
TH3_k127_1641049_2 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000001401 211.0
TH3_k127_1641049_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000002693 191.0
TH3_k127_1641049_4 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000006265 157.0
TH3_k127_1641049_5 COG1100 GTPase SAR1 and related small G - - - 0.0000000000000000000000003945 115.0
TH3_k127_1641049_6 OmpA family - - - 0.00000001174 68.0
TH3_k127_1641049_7 short-chain dehydrogenase reductase K21702 - 1.1.1.406 0.00001017 47.0
TH3_k127_1655372_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000005515 263.0
TH3_k127_1655372_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000229 244.0
TH3_k127_1655372_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000002892 241.0
TH3_k127_1655372_3 PFAM AIR synthase related protein K07123 - - 0.0000000000005005 71.0
TH3_k127_1655372_4 Probable zinc-ribbon domain - - - 0.00000005794 53.0
TH3_k127_1657756_0 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 359.0
TH3_k127_1657756_1 PFAM Peptidase family M20 M25 M40 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 320.0
TH3_k127_1657756_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000002289 196.0
TH3_k127_1657756_3 Domain of unknown function (DUF749) - - - 0.00002219 50.0
TH3_k127_1693600_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.421e-254 794.0
TH3_k127_1693600_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 2.119e-195 625.0
TH3_k127_1693600_2 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 310.0
TH3_k127_1693600_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000172 291.0
TH3_k127_1693600_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003704 268.0
TH3_k127_1693600_5 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000002858 247.0
TH3_k127_1693600_6 - - - - 0.00000000000000000000000000000000000000004352 169.0
TH3_k127_1693600_7 SPFH domain-Band 7 family - - - 0.0000000000000002705 81.0
TH3_k127_1743872_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000009728 281.0
TH3_k127_1743872_1 PFAM Major Facilitator Superfamily K19576 - - 0.0000000000000000000000000000000000000000000000000000009175 207.0
TH3_k127_1743872_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000002622 123.0
TH3_k127_1743872_3 Family of unknown function (DUF1028) - - - 0.000000000000001306 84.0
TH3_k127_1743872_4 - - - - 0.0000000002302 63.0
TH3_k127_1753000_0 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000001455 244.0
TH3_k127_1753000_1 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000005018 169.0
TH3_k127_1753000_2 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.0000000000000000000000000000000000001641 145.0
TH3_k127_1753000_3 Protein of unknown function (DUF1616) - - - 0.0000000000000000000004135 103.0
TH3_k127_1753000_4 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000002448 80.0
TH3_k127_1757954_0 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 390.0
TH3_k127_1757954_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000001641 165.0
TH3_k127_1757954_2 Glycine cleavage H-protein K02437 - - 0.00000000000000000000000000000000000000006897 155.0
TH3_k127_1757954_3 flavin reductase - - - 0.0000000000000000000000000000000000001269 148.0
TH3_k127_1757954_4 - - - - 0.0000006433 60.0
TH3_k127_1781899_0 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 389.0
TH3_k127_1781899_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000139 226.0
TH3_k127_1781899_2 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000000004506 189.0
TH3_k127_1781899_3 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.00000000000000002347 93.0
TH3_k127_1789413_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000003506 101.0
TH3_k127_1789413_1 Mitochondrial PGP phosphatase K07015 - - 0.0001153 52.0
TH3_k127_1842588_0 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 349.0
TH3_k127_1842588_1 COG0608 Single-stranded DNA-specific exonuclease K07463 - - 0.00000000000000000000000000000000000000000000000000005013 194.0
TH3_k127_1845935_0 Type II/IV secretion system protein K07332 - - 2.028e-225 712.0
TH3_k127_1845935_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 627.0
TH3_k127_1845935_2 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 415.0
TH3_k127_1845935_3 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 399.0
TH3_k127_1845935_4 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001361 287.0
TH3_k127_1845935_5 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000004386 242.0
TH3_k127_1845935_6 Protein of unknown function (DUF531) K09725 - - 0.0000000000000000000000000000000000000000000000000000004539 198.0
TH3_k127_1845935_7 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000002137 175.0
TH3_k127_1845935_8 - - - - 0.0000000000000000000000002337 111.0
TH3_k127_1845935_9 toxin activity - - - 0.00000000000000000000118 106.0
TH3_k127_1865939_0 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000004033 198.0
TH3_k127_1865939_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000003656 169.0
TH3_k127_1865939_2 YjbR - - - 0.0000000000000001467 84.0
TH3_k127_1865939_3 Saccharopine dehydrogenase - - - 0.000000000000006002 81.0
TH3_k127_1865939_4 - - - - 0.000000002439 61.0
TH3_k127_1865939_5 aminotransferase class I and II K00812 - 2.6.1.1 0.000000004797 58.0
TH3_k127_1865939_6 Glyoxalase-like domain - - - 0.0007574 51.0
TH3_k127_1870154_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 455.0
TH3_k127_1870154_1 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000005208 240.0
TH3_k127_1870154_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000005301 257.0
TH3_k127_1904867_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 449.0
TH3_k127_1904867_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 329.0
TH3_k127_1904867_2 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000008238 165.0
TH3_k127_1904867_3 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000215 161.0
TH3_k127_1904867_4 - - - - 0.000000001079 63.0
TH3_k127_1904867_5 phosphohydrolase, HD sub domain - - - 0.00000005139 66.0
TH3_k127_1931935_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005164 262.0
TH3_k127_1931935_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000005981 174.0
TH3_k127_1937032_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 583.0
TH3_k127_1937032_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 413.0
TH3_k127_1937032_2 Family 5 K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000003601 239.0
TH3_k127_1937032_3 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000004433 226.0
TH3_k127_1937032_4 Methyltransferase domain - - - 0.0000000000000000000000000001311 124.0
TH3_k127_1937032_5 Pfam:DUF59 - - - 0.00000000000000000007797 92.0
TH3_k127_1949155_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 323.0
TH3_k127_1949155_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000002404 171.0
TH3_k127_1949155_2 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000007656 96.0
TH3_k127_1960819_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.00000000000000000000000000000002015 142.0
TH3_k127_1960819_1 Acetyltransferase (GNAT) family - - - 0.0000000000004318 78.0
TH3_k127_1988819_0 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000001169 201.0
TH3_k127_1988819_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.00000000000000000000000000000000000001208 164.0
TH3_k127_1998046_0 chlorophyll binding K13275,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000002209 269.0
TH3_k127_1998046_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000009347 88.0
TH3_k127_2000006_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 367.0
TH3_k127_2000006_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 361.0
TH3_k127_2000006_2 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000001071 151.0
TH3_k127_2000006_3 Peptidase family S58 - - - 0.00001271 48.0
TH3_k127_2021276_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.839e-254 797.0
TH3_k127_2021276_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 556.0
TH3_k127_2021276_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00003453 46.0
TH3_k127_2043639_0 Clostripain family - - - 0.000000000000000000000000000000000000000000000000000000000000000008235 257.0
TH3_k127_2043639_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000003869 232.0
TH3_k127_2043639_2 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000003614 146.0
TH3_k127_2047791_0 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 502.0
TH3_k127_2047791_1 TIGRFAM PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 397.0
TH3_k127_2047791_2 Major facilitator superfamily - - - 0.0001744 49.0
TH3_k127_2047791_3 hmm pf00892 K08978 - - 0.0003186 52.0
TH3_k127_2054236_0 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000006411 196.0
TH3_k127_2054236_1 Double zinc ribbon - - - 0.0008695 50.0
TH3_k127_2085097_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000006133 212.0
TH3_k127_2085097_1 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000003061 196.0
TH3_k127_2085097_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000002154 167.0
TH3_k127_2089473_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000003251 234.0
TH3_k127_2089473_1 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000001356 163.0
TH3_k127_2094128_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 415.0
TH3_k127_2094128_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004427 290.0
TH3_k127_2158031_0 and related - - - 0.0000000000000000000000000000000000000000000000000000137 200.0
TH3_k127_2158031_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000001259 177.0
TH3_k127_2158031_2 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K13010 - 2.6.1.102 0.0000000000000000000000000000000007284 134.0
TH3_k127_2158031_3 Required for chromosome condensation and partitioning K03529 - - 0.000000001966 58.0
TH3_k127_2279093_0 acetyl-CoA hydrolase transferase - - - 8.644e-217 691.0
TH3_k127_2289829_0 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 328.0
TH3_k127_2289829_1 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000000000000000001336 200.0
TH3_k127_2289829_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02488 - 2.7.7.65 0.000000000000001184 81.0
TH3_k127_2289829_3 EamA-like transporter family K08978 - - 0.00000006339 61.0
TH3_k127_2293385_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 386.0
TH3_k127_2293385_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 307.0
TH3_k127_2293385_2 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000006362 166.0
TH3_k127_2293385_3 PFAM CBS domain - - - 0.00000000001785 68.0
TH3_k127_2298491_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 485.0
TH3_k127_2298491_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002317 280.0
TH3_k127_2298491_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000000000000000000000000000000000006129 254.0
TH3_k127_2298491_3 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000005761 167.0
TH3_k127_2298491_4 membrane-associated protein domain - - - 0.00000009365 57.0
TH3_k127_2298491_5 Protein of unknown function (DUF3198) - - - 0.000008454 53.0
TH3_k127_2330056_0 - - - - 0.00000000000000000000000000000000000000000000000000000002354 207.0
TH3_k127_2330056_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000008987 143.0
TH3_k127_2330056_2 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000003076 96.0
TH3_k127_2330056_3 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000005311 87.0
TH3_k127_2335711_0 helicase superfamily c-terminal domain K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 575.0
TH3_k127_2335711_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 414.0
TH3_k127_2335711_2 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 329.0
TH3_k127_2335711_3 Trimethylamine methyltransferase MttB (TMA methyltransferase) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000006857 278.0
TH3_k127_2335711_4 UbiD family - - - 0.0000000000000000000000000341 109.0
TH3_k127_2335711_5 Iron-sulphur cluster biosynthesis K15724 - - 0.00000000000000001828 87.0
TH3_k127_2335711_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000000000265 83.0
TH3_k127_2335711_7 - - - - 0.000000015 60.0
TH3_k127_2373433_0 - - - - 0.0000000000000000000000000000000000000000000000002735 182.0
TH3_k127_2373433_1 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000001112 136.0
TH3_k127_2373433_2 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000002389 113.0
TH3_k127_2373433_3 Clostripain family - - - 0.00000000000000000004784 105.0
TH3_k127_2373433_4 membrane - - - 0.00001302 55.0
TH3_k127_239637_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002797 282.0
TH3_k127_239637_1 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006112 245.0
TH3_k127_239637_2 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000000000000000000000000000000000003054 205.0
TH3_k127_239637_3 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000008034 130.0
TH3_k127_2400278_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000003281 243.0
TH3_k127_2400278_1 Prokaryotic homologs of the JAB domain - - - 0.0000000000000000000000000000003412 134.0
TH3_k127_2400278_2 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000001278 128.0
TH3_k127_2409036_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 401.0
TH3_k127_2409036_1 peptide-methionine (R)-S-oxide reductase activity K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000003197 185.0
TH3_k127_2409036_2 4Fe-4S binding domain - - - 0.0000000000000000003568 92.0
TH3_k127_2439065_0 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000001585 116.0
TH3_k127_2439529_0 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 432.0
TH3_k127_2439529_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 313.0
TH3_k127_2439529_2 Belongs to the UPF0292 family - - - 0.000000000000000000386 92.0
TH3_k127_2470055_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000002803 154.0
TH3_k127_2470055_1 Alpha-L-arabinofuranosidase C-terminal domain - - - 0.00000000000000000006523 100.0
TH3_k127_2470055_2 Dystroglycan-type cadherin domain protein - - - 0.0000000141 70.0
TH3_k127_2470055_3 COG3209 Rhs family protein - - - 0.0000000141 70.0
TH3_k127_2493481_0 Dehydratase family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 456.0
TH3_k127_2493481_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 397.0
TH3_k127_2493481_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000009198 109.0
TH3_k127_2518905_0 Peptidase family S51 - - - 0.0000000000000000000000000000000000000000000000000000000000004524 218.0
TH3_k127_2518905_1 PFAM RibD C-terminal domain K14654 - 1.1.1.302 0.0000000000000000000000005858 108.0
TH3_k127_2518905_2 PFAM ABC-type thiamin-related transport system, permease component 1 K16925 - - 0.00000000000000000001161 96.0
TH3_k127_2518905_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000007301 97.0
TH3_k127_2518905_4 Parallel beta-helix repeats - - - 0.0000000000000123 88.0
TH3_k127_2523382_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000000000000000000000000000000000000006027 149.0
TH3_k127_2523382_1 - - - - 0.000001075 57.0
TH3_k127_2541556_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 389.0
TH3_k127_2541556_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 314.0
TH3_k127_2541556_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000169 218.0
TH3_k127_2541556_3 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000001347 210.0
TH3_k127_2541556_4 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000002412 59.0
TH3_k127_2541556_5 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0004714 52.0
TH3_k127_2590145_0 helicase superfamily c-terminal domain K03724 - - 5.168e-207 663.0
TH3_k127_2590145_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000355 203.0
TH3_k127_2597603_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 365.0
TH3_k127_2597603_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 310.0
TH3_k127_2597603_2 PFAM Metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 301.0
TH3_k127_2597603_3 arginine decarboxylase activity K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000001739 261.0
TH3_k127_2597603_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000001201 69.0
TH3_k127_2597603_5 - - - - 0.00000001096 65.0
TH3_k127_2640318_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 527.0
TH3_k127_2640318_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 516.0
TH3_k127_2640318_2 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 384.0
TH3_k127_2640318_3 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000001286 213.0
TH3_k127_2640318_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000001726 193.0
TH3_k127_2640318_5 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000005398 160.0
TH3_k127_2640318_6 Transcriptional regulator, MarR family - - - 0.0003196 46.0
TH3_k127_2646924_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 460.0
TH3_k127_2646924_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 346.0
TH3_k127_2646924_2 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000613 223.0
TH3_k127_2646924_3 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000169 207.0
TH3_k127_2646924_4 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000921 131.0
TH3_k127_2646924_5 snRNP Sm proteins K04796 - - 0.00000000000000000000001001 101.0
TH3_k127_2646924_6 TIGRFAM segregation and condensation protein B K06024 - - 0.0000000000000000000008442 98.0
TH3_k127_268601_0 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000009222 137.0
TH3_k127_268601_1 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000001801 123.0
TH3_k127_268601_2 EamA-like transporter family - - - 0.00000002205 65.0
TH3_k127_2686104_0 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001736 269.0
TH3_k127_2686104_1 mandelate racemase muconate lactonizing K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000001749 218.0
TH3_k127_2686104_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000003479 108.0
TH3_k127_2686104_3 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000001424 67.0
TH3_k127_2694828_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000001042 136.0
TH3_k127_2694828_1 PFAM CBS domain containing protein - - - 0.000000000001086 70.0
TH3_k127_2708397_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 501.0
TH3_k127_2708397_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 346.0
TH3_k127_2708397_2 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 308.0
TH3_k127_2708397_3 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0006697 45.0
TH3_k127_2708868_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 299.0
TH3_k127_2708868_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000346 265.0
TH3_k127_2708868_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000131 243.0
TH3_k127_2708868_3 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000000000000000000005879 202.0
TH3_k127_2708868_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000004616 163.0
TH3_k127_2708868_5 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000002459 161.0
TH3_k127_2708868_6 PFAM Forkhead-associated protein - - - 0.000000000000000000000002653 119.0
TH3_k127_2793437_0 Glutamate synthase - - - 7.383e-195 620.0
TH3_k127_2793437_1 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 359.0
TH3_k127_2793437_2 GXGXG motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000124 268.0
TH3_k127_2848313_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000001229 239.0
TH3_k127_2848313_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000002319 192.0
TH3_k127_2848313_2 Major Facilitator - - - 0.00000000000002209 80.0
TH3_k127_2848313_3 - - - - 0.0000000000001278 78.0
TH3_k127_2880633_0 PFAM Aminotransferase class-III K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000004633 223.0
TH3_k127_2880633_2 Uncharacterised protein family (UPF0147) K09721 - - 0.00000000000000000000002922 100.0
TH3_k127_2880633_3 Domain of unknown function (DUF296) K06934 - - 0.00000000000001399 79.0
TH3_k127_2960843_0 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001068 280.0
TH3_k127_2960843_1 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000006779 222.0
TH3_k127_2960843_2 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000111 104.0
TH3_k127_2972487_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 566.0
TH3_k127_2972487_1 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 296.0
TH3_k127_2972487_2 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000004168 182.0
TH3_k127_2972487_3 - - - - 0.00002946 51.0
TH3_k127_2973059_0 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 318.0
TH3_k127_2973059_1 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000003958 220.0
TH3_k127_2973059_2 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000005826 105.0
TH3_k127_2973059_3 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.000000000001752 68.0
TH3_k127_2973059_4 PFAM amino acid-binding ACT domain protein - - - 0.0000002722 58.0
TH3_k127_2973059_5 PFAM RNA-binding protein - - - 0.0001414 46.0
TH3_k127_3033911_0 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004331 280.0
TH3_k127_3033911_1 B12 binding domain K14084 - - 0.00000000000000000000000000000000000000000000000001269 188.0
TH3_k127_3033911_2 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000001093 159.0
TH3_k127_3033911_3 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.00000000000000000000000000000005929 139.0
TH3_k127_3039087_0 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002818 285.0
TH3_k127_3039087_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000007475 210.0
TH3_k127_3039087_2 MGS-like domain K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000003057 160.0
TH3_k127_3104328_0 Methionine biosynthesis protein MetW K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000007792 145.0
TH3_k127_3104328_1 - - - - 0.000000000000003028 86.0
TH3_k127_3104328_2 Clostripain family - - - 0.0000003717 63.0
TH3_k127_3104328_3 COG0454 Histone acetyltransferase HPA2 and related - - - 0.0004736 50.0
TH3_k127_3108594_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 458.0
TH3_k127_3108594_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 351.0
TH3_k127_3108594_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 302.0
TH3_k127_3108594_3 ribosomal small subunit binding - - - 0.00000000001109 75.0
TH3_k127_3108594_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00004587 46.0
TH3_k127_3122847_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 435.0
TH3_k127_3122847_1 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000002377 108.0
TH3_k127_3122847_2 phenylalanine-tRNA ligase activity K01889 - 6.1.1.20 0.00000000000000000008501 94.0
TH3_k127_3123233_0 Glycosyl transferase family 2 - - - 0.000000000000001333 86.0
TH3_k127_3123233_1 PAS domain K02488 - 2.7.7.65 0.000000000000003614 83.0
TH3_k127_3157389_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 434.0
TH3_k127_3157389_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000000003262 78.0
TH3_k127_3188916_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1079.0
TH3_k127_3188916_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002911 279.0
TH3_k127_3214862_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.825e-195 623.0
TH3_k127_3214862_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000003446 170.0
TH3_k127_3214862_2 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.000000000000000000000004107 104.0
TH3_k127_3214862_3 hydrogenase maturation protease HycI K08315 - 3.4.23.51 0.000000000001149 77.0
TH3_k127_3214862_4 histidine kinase A domain protein - - - 0.00000003579 65.0
TH3_k127_3218593_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 451.0
TH3_k127_3218593_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 376.0
TH3_k127_3218593_2 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 317.0
TH3_k127_3218593_3 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 306.0
TH3_k127_3218593_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000006884 222.0
TH3_k127_3218593_5 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000000002928 151.0
TH3_k127_3218593_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.0000000000000000000000000000000000001062 158.0
TH3_k127_3218593_7 pfam yhs - - - 0.00000000000000007747 81.0
TH3_k127_3218593_8 Transcriptional - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000001439 80.0
TH3_k127_3262045_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 327.0
TH3_k127_3262045_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K02192,K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363 1.6.3.4,1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 305.0
TH3_k127_3262045_2 Double zinc ribbon - - - 0.0001057 49.0
TH3_k127_3268428_0 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001582 289.0
TH3_k127_3268428_1 Kelch motif - - - 0.000000000000000002107 100.0
TH3_k127_3286452_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 523.0
TH3_k127_3286452_1 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 337.0
TH3_k127_3286452_2 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001699 284.0
TH3_k127_3286452_3 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004778 273.0
TH3_k127_3286452_4 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001311 259.0
TH3_k127_3286452_5 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000001914 169.0
TH3_k127_3286452_6 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000001909 151.0
TH3_k127_3286452_7 Archaeal Type IV pilin, N-terminal - - - 0.00000000001356 77.0
TH3_k127_3286452_8 Rubrerythrin - - - 0.0000000000368 74.0
TH3_k127_3286452_9 Bacterial PH domain - - - 0.000000004009 65.0
TH3_k127_3295231_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 310.0
TH3_k127_3295231_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 321.0
TH3_k127_3295231_2 peptidase M20 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009743 293.0
TH3_k127_3295231_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001912 261.0
TH3_k127_3295231_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000002671 142.0
TH3_k127_3295231_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000008819 138.0
TH3_k127_3295231_6 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000002069 117.0
TH3_k127_3295231_7 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000001796 116.0
TH3_k127_3297531_0 PIN domain - - - 0.0000000000000000000000000000000000000004965 159.0
TH3_k127_3297531_2 PFAM Glutaredoxin K06191 - - 0.0000000000000000002436 90.0
TH3_k127_3297531_3 4Fe-4S binding domain - - - 0.00000000004642 66.0
TH3_k127_3309685_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000006286 178.0
TH3_k127_3309685_1 - - - - 0.00000000000000000000000000000000000000007856 164.0
TH3_k127_3309685_2 - - - - 0.0000000000000000001464 97.0
TH3_k127_3309685_4 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000004291 56.0
TH3_k127_3309685_5 Tetratricopeptide repeat - - - 0.0000009393 58.0
TH3_k127_3312072_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 610.0
TH3_k127_3312072_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 394.0
TH3_k127_3312072_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000001178 173.0
TH3_k127_3322659_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 434.0
TH3_k127_3322659_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 389.0
TH3_k127_3353427_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1082.0
TH3_k127_3353427_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 8.117e-268 846.0
TH3_k127_3353427_10 Band 7 protein K07192 - - 0.00000000000000000000000000000000000000000000000003166 199.0
TH3_k127_3353427_11 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000005 192.0
TH3_k127_3353427_12 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000006016 185.0
TH3_k127_3353427_13 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000581 117.0
TH3_k127_3353427_14 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000002021 92.0
TH3_k127_3353427_15 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000002398 86.0
TH3_k127_3353427_2 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 606.0
TH3_k127_3353427_3 Aminotransferase class-III K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 432.0
TH3_k127_3353427_4 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 416.0
TH3_k127_3353427_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 372.0
TH3_k127_3353427_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 349.0
TH3_k127_3353427_7 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002695 280.0
TH3_k127_3353427_8 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001129 264.0
TH3_k127_3353427_9 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000003856 212.0
TH3_k127_3366172_0 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 350.0
TH3_k127_3366172_1 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000002467 169.0
TH3_k127_3381368_0 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000001545 185.0
TH3_k127_3381368_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000005508 89.0
TH3_k127_3381368_2 Hep Hag repeat protein - - - 0.00000006601 63.0
TH3_k127_3392457_0 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000002594 243.0
TH3_k127_3392457_1 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000000008198 149.0
TH3_k127_3392457_2 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000263 139.0
TH3_k127_339539_0 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 308.0
TH3_k127_339539_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000000000000000000000000001958 194.0
TH3_k127_339539_2 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.0000000000000000000000000000000000000000000001495 180.0
TH3_k127_339539_3 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K03148,K21029 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779 2.7.7.73,2.7.7.80 0.0000000000000000000000000000001096 127.0
TH3_k127_3426021_0 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000001718 158.0
TH3_k127_3426021_1 - - - - 0.0000000000000000000000000000000000003516 145.0
TH3_k127_3469691_0 SMART ATPase, AAA type, core K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002619 266.0
TH3_k127_3469691_1 PFAM regulatory protein TetR - - - 0.000000000001664 72.0
TH3_k127_3469691_2 ABC-2 family transporter protein K01992 - - 0.0000000001596 70.0
TH3_k127_3495899_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000645 223.0
TH3_k127_3495899_1 - - - - 0.00000000000000000000000000000000000000000007414 179.0
TH3_k127_3495899_2 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000000000001328 109.0
TH3_k127_3495899_3 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000008455 51.0
TH3_k127_3544705_0 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000005196 142.0
TH3_k127_3544705_1 Peptidase family M28 - - - 0.000000000000000000000002751 115.0
TH3_k127_3544705_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000006589 88.0
TH3_k127_3549511_0 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 488.0
TH3_k127_3549511_1 - - - - 0.000000000000000000000000001874 112.0
TH3_k127_3608307_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.723e-265 839.0
TH3_k127_3608307_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 540.0
TH3_k127_3608307_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0003617 44.0
TH3_k127_361715_0 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000001393 175.0
TH3_k127_361715_1 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000002539 179.0
TH3_k127_361715_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000148 158.0
TH3_k127_361715_3 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000001093 129.0
TH3_k127_361715_4 Protein of unknown function (DUF835) - - - 0.0000000000000009069 90.0
TH3_k127_3619983_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 326.0
TH3_k127_3619983_1 Helix-hairpin-helix motif K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000000004717 235.0
TH3_k127_3619983_2 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000006443 123.0
TH3_k127_3619983_3 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.0000000000000000000000000691 112.0
TH3_k127_3619983_4 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000002848 78.0
TH3_k127_3657981_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 2.985e-215 688.0
TH3_k127_3657981_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000007247 247.0
TH3_k127_3657981_2 Enoyl-(Acyl carrier protein) reductase K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000377 233.0
TH3_k127_3657981_3 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000001348 184.0
TH3_k127_3657981_4 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000128 99.0
TH3_k127_3657981_5 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000001211 56.0
TH3_k127_3679017_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 486.0
TH3_k127_3679017_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 367.0
TH3_k127_3679017_2 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 376.0
TH3_k127_3679017_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000003221 247.0
TH3_k127_3679017_4 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.00000000000000000000000000000000000000000000001292 194.0
TH3_k127_3679017_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000006734 129.0
TH3_k127_3679017_6 Belongs to the UPF0280 family K09740 - - 0.0000004287 53.0
TH3_k127_3722657_0 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 359.0
TH3_k127_3722657_1 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000431 174.0
TH3_k127_3732842_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 440.0
TH3_k127_3732842_1 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 354.0
TH3_k127_3732842_2 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 341.0
TH3_k127_3738168_0 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004017 254.0
TH3_k127_3738168_1 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000003482 187.0
TH3_k127_3748945_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 451.0
TH3_k127_3748945_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 351.0
TH3_k127_3748945_2 methanogenesis marker protein 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 332.0
TH3_k127_3748945_3 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002839 250.0
TH3_k127_3748945_4 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.00000000000000000000000000000000000000000000000000000000000000001891 231.0
TH3_k127_3748945_5 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000000000000001683 164.0
TH3_k127_3748945_6 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000001884 160.0
TH3_k127_3748945_7 Protein of unknown function (DUF2797) - - - 0.000000007445 66.0
TH3_k127_3748945_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0001172 44.0
TH3_k127_3803841_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 584.0
TH3_k127_3803841_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 524.0
TH3_k127_3803841_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 441.0
TH3_k127_3803841_3 Pantothenate synthetase K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000001753 254.0
TH3_k127_3803841_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000002426 185.0
TH3_k127_3803841_5 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.0000000000000000000000000000000000000000000000003119 199.0
TH3_k127_3803841_6 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000001964 130.0
TH3_k127_3803841_7 chlorophyll binding - - - 0.00000000000000000000000005407 121.0
TH3_k127_3803841_8 - - - - 0.0000000000001523 74.0
TH3_k127_3803841_9 H ACA RNA-protein complex K07569 - - 0.000308 49.0
TH3_k127_3815547_0 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K00343,K22169 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 381.0
TH3_k127_3815547_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 377.0
TH3_k127_3815547_2 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000003937 214.0
TH3_k127_3815547_3 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000598 213.0
TH3_k127_3815547_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.00000000000001898 78.0
TH3_k127_3843997_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 436.0
TH3_k127_3843997_1 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 337.0
TH3_k127_3843997_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000003917 185.0
TH3_k127_3843997_3 SCP-2 sterol transfer family - - - 0.0000000002078 72.0
TH3_k127_3850403_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 514.0
TH3_k127_3850403_1 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 368.0
TH3_k127_3850403_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001017 278.0
TH3_k127_3850403_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000005632 231.0
TH3_k127_3850403_4 DNA alkylation repair enzyme - - - 0.0000000000000000000000000001883 117.0
TH3_k127_3850403_5 NADH ubiquinone oxidoreductase 27 kD subunit K00332,K22160 - 1.5.98.3,1.6.5.3 0.000000000000000000000000002537 117.0
TH3_k127_3850403_6 PFAM molybdopterin-guanine dinucleotide biosynthesis MobB region K03753 - - 0.00000000000000000000000001909 118.0
TH3_k127_3850403_7 NADH ubiquinone oxidoreductase subunit 3 (Chain a) K00330,K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3,1.6.5.3 0.00000000000000000000000002335 112.0
TH3_k127_3856870_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 3.474e-231 732.0
TH3_k127_3856870_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 487.0
TH3_k127_3933858_0 Cysteine-rich domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 370.0
TH3_k127_3933858_1 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000004602 156.0
TH3_k127_3933858_2 4Fe-4S dicluster domain - - - 0.000000001207 70.0
TH3_k127_3933858_3 zinc-ribbon domain - - - 0.0000139 52.0
TH3_k127_3956471_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 360.0
TH3_k127_3956471_1 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000000002211 158.0
TH3_k127_4036136_0 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 418.0
TH3_k127_4036136_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 400.0
TH3_k127_4036136_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000164 287.0
TH3_k127_4036136_3 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007285 287.0
TH3_k127_4036136_4 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000000004471 190.0
TH3_k127_4036136_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000004539 188.0
TH3_k127_4036136_6 ICC-like phosphoesterases K06953 - - 0.00000000000000000000000000000000000000000000001689 183.0
TH3_k127_4036136_7 Uncharacterized ArCR, COG1888 K09732 - - 0.0000000000000000000000000003713 116.0
TH3_k127_4036136_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000002906 70.0
TH3_k127_4036136_9 Antifreeze protein type I - - - 0.000000006702 67.0
TH3_k127_4040494_0 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000006896 228.0
TH3_k127_4040494_1 Thermophilic metalloprotease (M29) - - - 0.00000000000000000000000001678 114.0
TH3_k127_4048590_0 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 422.0
TH3_k127_4048590_1 Glycosyltransferase Family 4 K13677 - 2.4.1.208 0.000000000000000000000000000000000000000000002471 179.0
TH3_k127_4048590_2 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000001596 112.0
TH3_k127_4048590_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0006611 48.0
TH3_k127_4053507_0 Galactose oxidase, central domain - - - 0.000000000000000000000000000000000000000000006481 181.0
TH3_k127_4053507_1 PFAM blue (type 1) copper domain protein - - - 0.0006215 44.0
TH3_k127_4055981_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.941e-216 683.0
TH3_k127_4055981_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 325.0
TH3_k127_4055981_2 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 307.0
TH3_k127_4055981_3 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007999 271.0
TH3_k127_4055981_4 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000002197 202.0
TH3_k127_4055981_5 structural constituent of ribosome K02907 - - 0.0000000000000000000000000000000000000000004203 162.0
TH3_k127_4055981_6 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000002052 151.0
TH3_k127_4055981_7 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000005972 150.0
TH3_k127_4055981_8 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000004389 139.0
TH3_k127_4055981_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0002839 44.0
TH3_k127_4056929_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 459.0
TH3_k127_4056929_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 374.0
TH3_k127_4056929_2 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000001267 108.0
TH3_k127_4095444_0 AAA domain K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 543.0
TH3_k127_4095444_1 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000005705 103.0
TH3_k127_4095444_2 ATP-dependent peptidase activity K01338 - 3.4.21.53 0.000000000000000001559 88.0
TH3_k127_4164613_0 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 394.0
TH3_k127_4164613_1 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000002068 187.0
TH3_k127_4164613_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000001325 168.0
TH3_k127_4164613_3 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00001286 48.0
TH3_k127_417766_0 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 456.0
TH3_k127_417766_1 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000001927 247.0
TH3_k127_417766_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000004551 175.0
TH3_k127_417766_3 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000000000005922 70.0
TH3_k127_4229447_0 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003204 251.0
TH3_k127_4229447_1 Peptidase dimerisation domain - - - 0.0000000000000000000000006064 111.0
TH3_k127_4342655_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 4.187e-283 887.0
TH3_k127_4342655_1 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000005219 236.0
TH3_k127_4342655_2 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000001433 211.0
TH3_k127_4342655_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0000000000000000000000000000000000000000000000003115 181.0
TH3_k127_4342655_4 PRC-barrel domain - - - 0.00000000000000000000000006052 109.0
TH3_k127_4342655_5 oxidoreductase subunit delta K00171 - 1.2.7.1 0.00000000000000000000009421 111.0
TH3_k127_4342655_6 Tetratricopeptide repeat - - - 0.000000001176 68.0
TH3_k127_4391281_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 4.655e-320 996.0
TH3_k127_4391281_1 Helix-turn-helix XRE-family like proteins K07728 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 290.0
TH3_k127_4391281_2 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000000000000573 183.0
TH3_k127_4391281_3 - - - - 0.00000000000000000000000005013 116.0
TH3_k127_4391281_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000001676 97.0
TH3_k127_4391281_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000008162 69.0
TH3_k127_4400329_0 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 374.0
TH3_k127_4400329_1 - - - - 0.0000000000000000000000000000000001176 139.0
TH3_k127_4400329_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000004272 63.0
TH3_k127_4414963_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 512.0
TH3_k127_4414963_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 420.0
TH3_k127_4414963_2 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 289.0
TH3_k127_4414963_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002749 254.0
TH3_k127_4414963_4 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000001566 222.0
TH3_k127_4414963_5 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.0000000000000000000000000000000000000000001452 162.0
TH3_k127_4414963_6 - - - - 0.00000001694 64.0
TH3_k127_4434096_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 337.0
TH3_k127_4434096_1 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003913 248.0
TH3_k127_4467426_0 - - - - 0.0000000000000000000000000000000000000000008607 161.0
TH3_k127_4467426_1 HELICc2 K10844 - 3.6.4.12 0.00000000000000000000000000000000000000001465 160.0
TH3_k127_4467426_2 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000191 135.0
TH3_k127_4467426_3 Thiamine-binding protein - - - 0.000000000000000000001518 103.0
TH3_k127_4467426_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0006577 50.0
TH3_k127_4487656_0 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 351.0
TH3_k127_4487656_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007942 285.0
TH3_k127_4487656_2 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000007385 172.0
TH3_k127_4487656_3 Transcriptional regulator, ArsR family - - - 0.000000000000000000000000000000000003351 147.0
TH3_k127_4487656_4 Mg2 transporter protein K03284 - - 0.00000000000000000000000000000000648 139.0
TH3_k127_4487656_5 Transcriptional regulator K07730 - - 0.0000000000000002306 89.0
TH3_k127_4487656_6 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000002697 79.0
TH3_k127_4512029_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000251 261.0
TH3_k127_4512029_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000001352 223.0
TH3_k127_4512029_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000002686 231.0
TH3_k127_4512029_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000006606 64.0
TH3_k127_4527877_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 334.0
TH3_k127_4527877_1 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000003836 250.0
TH3_k127_4541850_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657,K07023 - 2.3.1.57 0.0000000000000000000000000001281 121.0
TH3_k127_4541850_1 hmm pf03415 K08587 - 3.4.22.8 0.000000000000000000000002665 117.0
TH3_k127_4541850_2 Clostripain family - - - 0.0000000000000000000009643 108.0
TH3_k127_4541850_3 PFAM TPR repeat-containing protein - - - 0.0000000000000006204 92.0
TH3_k127_4561668_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000001936 199.0
TH3_k127_4561668_1 Winged helix-turn helix - - - 0.0000000000000000000000000000007998 128.0
TH3_k127_4614871_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 583.0
TH3_k127_4614871_1 oligoendopeptidase F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 353.0
TH3_k127_4619179_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 451.0
TH3_k127_4619179_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000003795 212.0
TH3_k127_4619179_2 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000000005376 101.0
TH3_k127_4619179_3 protein conserved in archaea - - - 0.0000005811 60.0
TH3_k127_4619179_4 response to antibiotic K21463 - - 0.00000791 55.0
TH3_k127_4619179_5 - - - - 0.00008728 52.0
TH3_k127_4638441_0 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 299.0
TH3_k127_4638441_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 298.0
TH3_k127_4638441_2 Oxidoreductase domain protein K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006573 286.0
TH3_k127_4638441_3 Cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000003562 216.0
TH3_k127_4638441_4 Trm112p-like protein - - - 0.000000000000002723 85.0
TH3_k127_4638441_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00001101 53.0
TH3_k127_463970_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 399.0
TH3_k127_463970_1 - - - - 0.000000000002456 72.0
TH3_k127_463970_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00007782 53.0
TH3_k127_4648042_0 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006501 282.0
TH3_k127_4648042_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000004468 207.0
TH3_k127_4648042_2 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000002773 179.0
TH3_k127_4648042_3 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000001424 146.0
TH3_k127_4655927_0 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 353.0
TH3_k127_4655927_1 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002922 269.0
TH3_k127_4655927_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007807 263.0
TH3_k127_4655927_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002208 271.0
TH3_k127_4655927_4 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000003572 256.0
TH3_k127_4655927_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02033,K12369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007182 251.0
TH3_k127_4655927_6 oxidoreductase activity - - - 0.000000000000000000000000000000001006 141.0
TH3_k127_4701244_0 PFAM Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000001089 222.0
TH3_k127_4701244_1 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000001362 196.0
TH3_k127_4701244_2 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000926 55.0
TH3_k127_4701244_3 (FHA) domain - - - 0.000131 49.0
TH3_k127_4724084_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001749 258.0
TH3_k127_4724084_1 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000000000000000000000000000000000005863 205.0
TH3_k127_4724084_2 FR47-like protein - - - 0.00000006332 63.0
TH3_k127_4736065_0 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007913 258.0
TH3_k127_4736065_1 Metal-dependent hydrolases of the beta-lactamase superfamily I K00784 - 3.1.26.11 0.0000000000000000000000000000000005267 138.0
TH3_k127_4740211_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 376.0
TH3_k127_4740211_1 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000001664 241.0
TH3_k127_4762156_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 569.0
TH3_k127_4762156_1 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 453.0
TH3_k127_4762156_2 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 346.0
TH3_k127_4762156_3 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003936 250.0
TH3_k127_4762156_4 Pfam:KaiC - - - 0.000000000000001424 77.0
TH3_k127_4762156_5 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000003233 65.0
TH3_k127_4795099_0 FAD binding domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 366.0
TH3_k127_4795099_1 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 285.0
TH3_k127_4795099_2 ABC-type cobalt transport system, permease K16785 - - 0.0000000000000000000000000000000000000000002794 168.0
TH3_k127_4795099_3 ECF-type riboflavin transporter, S component - - - 0.0000000000000000000000003225 117.0
TH3_k127_4812797_0 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 320.0
TH3_k127_4812797_1 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 313.0
TH3_k127_4812797_4 virion core protein, lumpy skin disease virus - - - 0.000007034 55.0
TH3_k127_4847908_0 Clostripain family - - - 0.00000000000000000000000000000000002066 153.0
TH3_k127_4856264_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 316.0
TH3_k127_4856264_1 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000003655 228.0
TH3_k127_4859147_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001864 256.0
TH3_k127_4859147_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000002021 246.0
TH3_k127_4859147_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000001572 228.0
TH3_k127_4859147_3 Laminin G domain - - - 0.0001115 53.0
TH3_k127_4913164_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000003167 137.0
TH3_k127_4913164_1 PAS fold - - - 0.00000000000000002658 96.0
TH3_k127_4946193_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 596.0
TH3_k127_4946193_1 Helix-hairpin-helix domain K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 301.0
TH3_k127_4960936_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 265.0
TH3_k127_4960936_1 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 0.000000000000000000000000000000000000002212 148.0
TH3_k127_4960936_2 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000002576 72.0
TH3_k127_4976748_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 530.0
TH3_k127_4976748_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 478.0
TH3_k127_4976748_2 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 435.0
TH3_k127_4976748_3 Thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 336.0
TH3_k127_4976748_4 PFAM Pyruvate carboxyltransferase K02594 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 324.0
TH3_k127_4976748_5 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000001527 207.0
TH3_k127_4976748_6 PFAM Prolyl oligopeptidase family - - - 0.000000000000009321 76.0
TH3_k127_5006489_0 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000489 226.0
TH3_k127_5006489_1 COG1361 S-layer domain - - - 0.0000000000000000000000932 108.0
TH3_k127_5006489_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000001678 63.0
TH3_k127_5046367_0 TIGRFAM Outer membrane protein K13735,K20276 - - 0.000000000000000000000000000000009676 145.0
TH3_k127_5056238_0 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 551.0
TH3_k127_5056238_1 Double zinc ribbon - - - 0.000000000000000000000000000000000000000000001504 190.0
TH3_k127_5056238_2 PFAM Nitroreductase K04719 - 1.13.11.79 0.00000000000000000000003277 109.0
TH3_k127_5064963_0 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000002812 169.0
TH3_k127_5064963_1 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000247 147.0
TH3_k127_5064963_2 Thioredoxin K03671 - - 0.0000000000000000000000000000000000008232 143.0
TH3_k127_5064963_3 PRC-barrel domain - - - 0.000000000000000004877 87.0
TH3_k127_5064963_4 glutamine amidotransferase K07008 - 3.5.1.118 0.0000000000004974 79.0
TH3_k127_5064963_5 OsmC-like protein - - - 0.000000005812 63.0
TH3_k127_5109000_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 6.55e-217 687.0
TH3_k127_5124188_0 amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000003843 184.0
TH3_k127_5124188_1 - - - - 0.0000000000000008686 80.0
TH3_k127_5164662_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 379.0
TH3_k127_5164662_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 382.0
TH3_k127_5164662_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 331.0
TH3_k127_5164662_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000001214 227.0
TH3_k127_5164662_4 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000001032 158.0
TH3_k127_5164662_5 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000002232 110.0
TH3_k127_5164662_6 - - - - 0.00000000000000000002953 96.0
TH3_k127_5175781_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003266 285.0
TH3_k127_5175781_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000106 172.0
TH3_k127_5180332_0 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 398.0
TH3_k127_5180332_1 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000003171 119.0
TH3_k127_5180332_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000002388 85.0
TH3_k127_5180332_3 Nickel-dependent hydrogenase K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000483 76.0
TH3_k127_5182188_0 LUD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005086 260.0
TH3_k127_5182188_1 Membrane - - - 0.00000000000000000000000000000000000000000001002 172.0
TH3_k127_5182188_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000803 143.0
TH3_k127_5193662_0 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 349.0
TH3_k127_5193662_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000001988 101.0
TH3_k127_5193662_2 KEOPS complex Cgi121-like subunit K09119 - - 0.0000000000002265 78.0
TH3_k127_5193662_3 PFAM Formiminotransferase-cyclodeaminase - - - 0.0000000001511 74.0
TH3_k127_5216901_0 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000008487 215.0
TH3_k127_5216901_1 exonuclease K07502 - - 0.000000000000000000000000000000000000000000000000002242 191.0
TH3_k127_5216901_2 Calcineurin-like phosphoesterase superfamily domain K06953 - - 0.00000000000000000000000000000000000000000487 163.0
TH3_k127_5216901_3 Small-conductance mechanosensitive channel - - - 0.000000000000000000004975 102.0
TH3_k127_5230632_0 glutathione-regulated potassium exporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002175 289.0
TH3_k127_5230632_1 Archaeal transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000000005459 228.0
TH3_k127_5230632_2 Radical SAM K06937 - - 0.00001125 51.0
TH3_k127_5248314_0 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009722 244.0
TH3_k127_5248314_1 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000001708 149.0
TH3_k127_5248314_2 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000005305 141.0
TH3_k127_5248314_3 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.000000000000000000001839 96.0
TH3_k127_5248314_4 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000278 89.0
TH3_k127_5248314_5 Rubrerythrin - - - 0.000000000002649 74.0
TH3_k127_5272205_0 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001791 277.0
TH3_k127_5272205_1 Nickel-dependent hydrogenase K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000003077 273.0
TH3_k127_5272205_2 hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000004289 208.0
TH3_k127_5321243_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 405.0
TH3_k127_5359601_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 508.0
TH3_k127_5374334_0 Proton-conducting membrane transporter K05565,K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255 285.0
TH3_k127_5374334_1 NADH ubiquinone oxidoreductase subunit 11 or 4L (Chain K) K00340,K22166 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000003838 119.0
TH3_k127_5374334_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000001637 73.0
TH3_k127_5374334_3 4Fe-4S dicluster domain - - - 0.00000004086 60.0
TH3_k127_5427364_0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000001109 73.0
TH3_k127_5427364_1 ACT domain protein - - - 0.0000000005132 65.0
TH3_k127_5427364_2 virion core protein, lumpy skin disease virus - - - 0.000002119 53.0
TH3_k127_5427931_0 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000133 282.0
TH3_k127_5427931_1 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000006527 180.0
TH3_k127_5427931_2 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000007976 116.0
TH3_k127_5427931_3 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000001611 113.0
TH3_k127_5427931_4 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000000003996 114.0
TH3_k127_5427931_5 PFAM DsrE family protein K07236 - - 0.0005539 47.0
TH3_k127_5459547_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 471.0
TH3_k127_5459547_1 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 481.0
TH3_k127_5459547_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 265.0
TH3_k127_5459547_3 peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000003733 223.0
TH3_k127_5459547_4 nitroreductase - - - 0.000000000000000000000000000000000000000000000002277 179.0
TH3_k127_5459547_5 nitrogen compound transport K02033,K12369 - - 0.0000000000000000000000000000000005837 135.0
TH3_k127_5459547_6 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000001842 126.0
TH3_k127_5459547_7 EamA-like transporter family - - - 0.000000000000000000007843 104.0
TH3_k127_5459547_8 TIGRFAM C_GCAxxG_C_C family - - - 0.0000000000001004 77.0
TH3_k127_5459547_9 - - - - 0.0001541 48.0
TH3_k127_5484094_0 Radical SAM domain protein K09711 - - 0.00000000000000000000000000000000000000000000000000000000002903 223.0
TH3_k127_5484094_1 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000001012 63.0
TH3_k127_5484094_2 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.00001888 50.0
TH3_k127_5521234_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 327.0
TH3_k127_5521234_1 UbiA prenyltransferase family K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000601 191.0
TH3_k127_5521234_2 Putative RNA methylase family UPF0020 K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000005484 172.0
TH3_k127_5554618_0 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000003245 222.0
TH3_k127_5554618_1 K homology RNA-binding domain K06961 - - 0.000000000000000000000000000000000000000000000000003399 188.0
TH3_k127_5554618_2 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000002884 149.0
TH3_k127_5554618_3 Arginosuccinate synthase - - - 0.000000000000000000000004178 109.0
TH3_k127_5595142_0 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 483.0
TH3_k127_5595142_1 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 394.0
TH3_k127_5595142_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000009414 149.0
TH3_k127_5595142_3 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.0000000000000000000000000000002942 126.0
TH3_k127_5635361_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.00000000000000000000000000000000000000000000000000001499 192.0
TH3_k127_5635361_1 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000000000000000000003286 154.0
TH3_k127_5635361_2 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000001811 97.0
TH3_k127_5635361_3 Homodimerisation domain of SGTA K16365 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006996,GO:0007029,GO:0008022,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009896,GO:0009987,GO:0010033,GO:0010243,GO:0010256,GO:0010498,GO:0010604,GO:0010605,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0019941,GO:0030162,GO:0030163,GO:0030433,GO:0030544,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031329,GO:0031330,GO:0031331,GO:0031333,GO:0032268,GO:0032269,GO:0032270,GO:0032434,GO:0032435,GO:0032436,GO:0032459,GO:0032460,GO:0033036,GO:0033365,GO:0033554,GO:0034613,GO:0034976,GO:0036503,GO:0042176,GO:0042177,GO:0042221,GO:0042802,GO:0042803,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0043621,GO:0043632,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045048,GO:0045184,GO:0045732,GO:0045861,GO:0045862,GO:0046982,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051087,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051205,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051603,GO:0051641,GO:0051716,GO:0060255,GO:0061024,GO:0061136,GO:0065007,GO:0070727,GO:0071704,GO:0071816,GO:0071840,GO:0072657,GO:0080090,GO:0080134,GO:0080135,GO:0090150,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901799,GO:1901800,GO:1903050,GO:1903051,GO:1903052,GO:1903069,GO:1903070,GO:1903071,GO:1903332,GO:1903334,GO:1903362,GO:1903363,GO:1903364,GO:1903573,GO:1903644,GO:1903646,GO:1904288,GO:1904292,GO:1904293,GO:1904294,GO:1905897,GO:1905898,GO:2000058,GO:2000059,GO:2000060 - 0.00005505 53.0
TH3_k127_5661868_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1169.0
TH3_k127_5661868_1 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000001113 214.0
TH3_k127_5661868_2 Evidence 5 No homology to any previously reported sequences - - - 0.00002145 57.0
TH3_k127_5687232_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 387.0
TH3_k127_5687232_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000276 247.0
TH3_k127_5687232_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000005554 122.0
TH3_k127_5687232_3 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000001272 128.0
TH3_k127_5800154_0 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000002918 261.0
TH3_k127_5800154_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000003361 156.0
TH3_k127_5800154_2 - - - - 0.000000000000004256 86.0
TH3_k127_5816330_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000003195 234.0
TH3_k127_5816330_1 - - - - 0.00000000000000000000000000000000000000000000000000001309 198.0
TH3_k127_5816330_2 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000003077 171.0
TH3_k127_5816330_3 TPR repeat-containing protein - - - 0.0000000000000000000006671 111.0
TH3_k127_5867468_0 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 424.0
TH3_k127_5867468_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 362.0
TH3_k127_5867468_2 Iron dependent K03709 - - 0.000000000000000000000000000000000000000000000007283 179.0
TH3_k127_5867468_3 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.0000000000002353 79.0
TH3_k127_5907483_0 Peptidase family C25 K03546,K20074 - 3.1.3.16 0.0000000000000000001079 105.0
TH3_k127_590768_0 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000002757 218.0
TH3_k127_590768_1 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000113 147.0
TH3_k127_590768_2 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.000000000000000000000001165 110.0
TH3_k127_590768_3 Acetyltransferase (GNAT) family - - - 0.0002896 45.0
TH3_k127_5914353_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.785e-199 642.0
TH3_k127_5914353_1 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 485.0
TH3_k127_5914353_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 439.0
TH3_k127_5914353_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 391.0
TH3_k127_5914353_4 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008543 253.0
TH3_k127_5914353_5 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000001681 246.0
TH3_k127_595478_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 472.0
TH3_k127_595478_1 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 400.0
TH3_k127_595478_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001275 245.0
TH3_k127_595478_3 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000001678 219.0
TH3_k127_595478_4 Domains REC, HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000000009786 185.0
TH3_k127_595478_5 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.0000000000000000000000000000000000000000001829 164.0
TH3_k127_595478_6 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.0000000000000000000000000000000006067 145.0
TH3_k127_595478_7 - - - - 0.0000000000002009 81.0
TH3_k127_595478_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000006455 73.0
TH3_k127_5968623_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 430.0
TH3_k127_5968623_1 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008144 273.0
TH3_k127_5968623_2 Lamin Tail Domain - - - 0.0000000000000000004768 98.0
TH3_k127_5973638_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 597.0
TH3_k127_5973638_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000006049 241.0
TH3_k127_5997570_0 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000002743 160.0
TH3_k127_5997570_1 GvpD gas vesicle protein - - - 0.0000000000000000000000000000000000000002263 157.0
TH3_k127_5997570_2 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.000000000000000000000000001275 119.0
TH3_k127_5997570_3 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000000000000000000004853 102.0
TH3_k127_5997570_4 cheY-homologous receiver domain - - - 0.00000000000000000006977 97.0
TH3_k127_5997570_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000003403 62.0
TH3_k127_6006768_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002645 255.0
TH3_k127_6006768_1 - - - - 0.000000000000000000000000000000000003023 151.0
TH3_k127_6006768_2 - - - - 0.00000000000002716 81.0
TH3_k127_6006768_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000006057 49.0
TH3_k127_6045004_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 311.0
TH3_k127_6045004_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 306.0
TH3_k127_6045004_2 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004508 281.0
TH3_k127_6045004_3 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.000000000000000000000000000000000000000000000000000000008705 214.0
TH3_k127_6045004_4 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000000005637 202.0
TH3_k127_6045004_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000002599 189.0
TH3_k127_6045004_6 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000000000104 165.0
TH3_k127_6045004_7 Ribbon-helix-helix protein, copG family K07722 - - 0.0000000000000000000005109 99.0
TH3_k127_6124498_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 477.0
TH3_k127_6124498_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 476.0
TH3_k127_6124498_2 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006909 272.0
TH3_k127_6124498_3 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003308 276.0
TH3_k127_6124498_4 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000000001316 106.0
TH3_k127_6124498_5 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000009422 78.0
TH3_k127_6124498_6 Pkd domain containing protein - - - 0.00000000005344 72.0
TH3_k127_6124498_7 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000003278 62.0
TH3_k127_6124498_8 Major Facilitator Superfamily - - - 0.000005878 58.0
TH3_k127_612604_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 558.0
TH3_k127_612604_1 NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K17994,K18007 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 347.0
TH3_k127_612604_2 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 309.0
TH3_k127_612604_3 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000006055 225.0
TH3_k127_612604_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000002217 63.0
TH3_k127_6159242_0 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 330.0
TH3_k127_6159242_1 pfam nmd3 K07562 - - 0.00000000000000000000000001469 117.0
TH3_k127_6159242_2 Fe-S type, tartrate fumarate subfamily, beta K01678,K03780 - 4.2.1.2,4.2.1.32 0.0007747 43.0
TH3_k127_617950_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002567 265.0
TH3_k127_617950_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000006174 253.0
TH3_k127_617950_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008595 261.0
TH3_k127_617950_3 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000004311 197.0
TH3_k127_617950_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000008676 75.0
TH3_k127_617950_5 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000003496 76.0
TH3_k127_6181904_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 510.0
TH3_k127_6195871_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000151 222.0
TH3_k127_6195871_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000003674 119.0
TH3_k127_6195871_2 amine dehydrogenase activity - - - 0.00000000000000006301 96.0
TH3_k127_6200927_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001013 248.0
TH3_k127_6200927_1 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000137 193.0
TH3_k127_6200927_2 COG0530 Ca2 Na antiporter K07301 GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005262,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0008150,GO:0008273,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015081,GO:0015085,GO:0015267,GO:0015291,GO:0015297,GO:0015298,GO:0015318,GO:0015368,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0019725,GO:0022803,GO:0022804,GO:0022821,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030955,GO:0031224,GO:0031226,GO:0031402,GO:0031420,GO:0034220,GO:0035725,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070588,GO:0070838,GO:0071804,GO:0071805,GO:0071944,GO:0072503,GO:0072507,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516 - 0.00000000000000000000000000000000000005764 156.0
TH3_k127_6200927_3 ADP-ribosylation factor family - - - 0.0000000000000000000000000002152 122.0
TH3_k127_6200927_4 excinuclease ABC, C subunit - - - 0.0000000000000000000000009624 109.0
TH3_k127_6200927_5 Protein of unknown function (DUF1614) - - - 0.0000000000001836 80.0
TH3_k127_6200927_6 Major facilitator superfamily K02575 - - 0.0000003456 62.0
TH3_k127_6212223_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 475.0
TH3_k127_6212223_1 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 291.0
TH3_k127_6212223_2 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009772 290.0
TH3_k127_6212223_3 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000000000000000000000000000000000000000004304 181.0
TH3_k127_6212223_4 EamA-like transporter family - - - 0.00000000000000000000005633 110.0
TH3_k127_6212223_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000004068 95.0
TH3_k127_6212223_6 Belongs to the UPF0273 family - - - 0.000000000001576 77.0
TH3_k127_6238915_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 362.0
TH3_k127_6238915_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000001481 173.0
TH3_k127_6238915_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000001192 141.0
TH3_k127_6311682_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000006206 256.0
TH3_k127_6311682_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000001324 186.0
TH3_k127_6311682_2 COG0438 Glycosyltransferase - - - 0.0000000003664 72.0
TH3_k127_6311682_3 glycosyl transferase, family 2 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000001204 63.0
TH3_k127_6314840_0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000000002306 184.0
TH3_k127_6314840_1 KaiC - - - 0.00000000000000000000000000000000007466 145.0
TH3_k127_6314840_2 Pfam:KaiC - - - 0.0000000000000000000000000000008661 135.0
TH3_k127_6314840_3 MFS_1 like family K08153 - - 0.0000000000000000000000003577 117.0
TH3_k127_6314840_4 In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha- aminoadipate (AAA) pathway K06154 - - 0.000000000002695 71.0
TH3_k127_637382_0 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 377.0
TH3_k127_637382_1 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000003222 91.0
TH3_k127_637382_2 - - - - 0.00003322 54.0
TH3_k127_6459471_0 COG COG0714 MoxR-like ATPases General function prediction only - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001056 285.0
TH3_k127_6459471_1 FR47-like protein - - - 0.0000000000000001616 86.0
TH3_k127_6475429_0 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 389.0
TH3_k127_6475429_1 4Fe-4S binding domain K18979 - 1.17.99.6 0.0000000000000000000000002375 108.0
TH3_k127_6475429_2 Response regulator receiver domain - - - 0.0000000000000000004286 93.0
TH3_k127_6475429_3 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000000001992 60.0
TH3_k127_6475429_4 redox-active disulfide protein 2 - - - 0.00008419 48.0
TH3_k127_6483099_0 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001326 229.0
TH3_k127_6483099_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000002746 208.0
TH3_k127_6483099_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000357 199.0
TH3_k127_6483099_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001024 191.0
TH3_k127_6483099_4 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000002494 176.0
TH3_k127_6483099_5 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001027 177.0
TH3_k127_6483099_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000001319 153.0
TH3_k127_6483099_7 ribosomal protein S14 K02954 - - 0.000000000000000006272 92.0
TH3_k127_6497272_0 alcohol dehydrogenase K00008,K00060 - 1.1.1.103,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 323.0
TH3_k127_6497272_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.0000000000000000000000000000000000000000000000000000002064 199.0
TH3_k127_6497272_2 5'-3' exoribonuclease activity K12574 - - 0.00000000000000000000000000000000000000000000001721 182.0
TH3_k127_6511810_0 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000256 263.0
TH3_k127_6511810_1 TIGRFAM TIGR00268 family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000003557 242.0
TH3_k127_6511810_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000000000002788 121.0
TH3_k127_6511810_3 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576 2.7.4.26 0.00000000000000000007224 93.0
TH3_k127_6538565_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000028 274.0
TH3_k127_6538565_1 HisG, C-terminal domain K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000008675 271.0
TH3_k127_6538565_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000005328 117.0
TH3_k127_6538565_3 cheY-homologous receiver domain K03413 - - 0.0000000000000000001435 93.0
TH3_k127_6538565_4 but it may be involved in stabilization of the trimeric complex - - - 0.0000000004574 61.0
TH3_k127_6632272_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000003729 271.0
TH3_k127_6632272_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000004339 273.0
TH3_k127_6632272_2 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000001854 84.0
TH3_k127_6723874_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000004146 175.0
TH3_k127_6723874_1 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000001269 157.0
TH3_k127_6723874_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000002846 152.0
TH3_k127_6723874_3 sequence-specific DNA binding - - - 0.000000001519 62.0
TH3_k127_6758458_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000004455 225.0
TH3_k127_6758458_1 - - - - 0.000000000000000000000000001017 117.0
TH3_k127_6758458_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000001125 91.0
TH3_k127_6766707_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.00000000000000000932 98.0
TH3_k127_6766707_1 Double zinc ribbon - - - 0.00006979 53.0
TH3_k127_6802784_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 491.0
TH3_k127_6802784_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000002016 166.0
TH3_k127_6802784_2 PFAM Thiolase K00626 - 2.3.1.9 0.000000001966 58.0
TH3_k127_6831817_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000001101 164.0
TH3_k127_6831817_1 - - - - 0.0000000000000000000000000000000002753 139.0
TH3_k127_6831817_2 PFAM AIR synthase related protein K07123 - - 0.00000000000000006106 84.0
TH3_k127_686125_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 324.0
TH3_k127_686125_1 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 291.0
TH3_k127_686125_2 peptidase dimerisation domain protein K01439 - 3.5.1.18 0.0000000000000000000000000000008115 133.0
TH3_k127_686125_3 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000001623 102.0
TH3_k127_6867817_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 434.0
TH3_k127_6867817_1 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000001365 198.0
TH3_k127_6867817_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000001502 188.0
TH3_k127_6867817_3 membrane K08971 - - 0.00000000000000000000000000000008521 141.0
TH3_k127_6867817_4 Belongs to the UPF0248 family K09715 - - 0.00000000000000000000006356 100.0
TH3_k127_6870842_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000008867 182.0
TH3_k127_6870842_1 PFAM CBS domain containing protein - - - 0.00000000001272 72.0
TH3_k127_6977036_0 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009786 261.0
TH3_k127_6977036_1 - - - - 0.00000000000000000000000000000000005664 154.0
TH3_k127_6977036_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000007278 64.0
TH3_k127_7006469_0 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000002104 116.0
TH3_k127_7038234_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1296.0
TH3_k127_7038234_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 3.986e-247 767.0
TH3_k127_7107594_0 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000004734 220.0
TH3_k127_7107594_1 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 0.0000000000000000000000000000000000000000000004251 168.0
TH3_k127_7107594_2 Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000000000000347 137.0
TH3_k127_7109871_0 PFAM Acetyltransferase (GNAT) family - - - 0.0000000001176 72.0
TH3_k127_7109871_1 PFAM periplasmic copper-binding - - - 0.0000006149 59.0
TH3_k127_7114732_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 5.982e-228 718.0
TH3_k127_7114732_1 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 479.0
TH3_k127_7114732_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 362.0
TH3_k127_7114732_3 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000001007 200.0
TH3_k127_7114732_4 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.000000000000000000000001614 111.0
TH3_k127_7114732_5 Pfam:DUF59 - - - 0.000000000000000007874 86.0
TH3_k127_7114732_6 PKD domain K01176,K01179,K02395,K21429 - 3.2.1.1,3.2.1.4 0.0000000002082 62.0
TH3_k127_7114732_7 Pentapeptide repeats (8 copies) - - - 0.0003768 50.0
TH3_k127_7127183_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001145 272.0
TH3_k127_7127183_1 nitrogen compound transport K02033,K12369 - - 0.00000000000000000000000000000000000000000000000000000000000000000185 238.0
TH3_k127_7127183_2 Psort location Cytoplasmic, score 8.87 - - - 0.000006375 54.0
TH3_k127_7177400_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 438.0
TH3_k127_7177400_1 PFAM isocitrate isopropylmalate dehydrogenase K05824 - 1.1.1.87 0.0000000000000000000000000000693 120.0
TH3_k127_7177400_2 signal transduction protein with CBS domains K07744 - - 0.00001617 50.0
TH3_k127_7180236_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003855 271.0
TH3_k127_7180236_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000009466 155.0
TH3_k127_7192486_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 3.45e-261 831.0
TH3_k127_7192486_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 563.0
TH3_k127_7192486_2 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 524.0
TH3_k127_7192486_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 335.0
TH3_k127_7192486_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003882 259.0
TH3_k127_7192486_5 PFAM Peptidase - - - 0.00000000000000000000000000000000002914 143.0
TH3_k127_7192486_6 Ribonuclease H K03469 - 3.1.26.4 0.0000000000000000000000000007303 117.0
TH3_k127_7192486_7 - - - - 0.00000000000000004643 92.0
TH3_k127_7195940_0 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 1.303e-195 625.0
TH3_k127_7195940_1 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 451.0
TH3_k127_7195940_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003188 282.0
TH3_k127_7195940_3 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002441 270.0
TH3_k127_7195940_4 Universal stress protein family - - - 0.0000000000000000000000000000502 120.0
TH3_k127_7200097_0 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002316 295.0
TH3_k127_7200097_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000001045 59.0
TH3_k127_7200097_2 ACT domain protein - - - 0.000002384 55.0
TH3_k127_7210397_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 528.0
TH3_k127_7227406_0 TIGRFAM cysteine desulfurase family protein - - - 0.00000000000000000000000000000000000000000771 165.0
TH3_k127_7227406_1 - - - - 0.00000000000000000006501 104.0
TH3_k127_7227406_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000001476 98.0
TH3_k127_727032_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 454.0
TH3_k127_727032_1 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 292.0
TH3_k127_727032_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006769 273.0
TH3_k127_727032_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000136 246.0
TH3_k127_7271661_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.705e-221 699.0
TH3_k127_7271661_1 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000003032 234.0
TH3_k127_7271661_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000006054 155.0
TH3_k127_7271661_3 Formate hydrogenlyase K12136,K15827 - - 0.000000000000000000000000000007584 124.0
TH3_k127_7271661_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000001343 90.0
TH3_k127_728360_0 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 376.0
TH3_k127_728360_1 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000007733 193.0
TH3_k127_728360_2 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000001118 168.0
TH3_k127_728360_3 - - - - 0.000000002774 66.0
TH3_k127_728360_4 Esterase PHB depolymerase - - - 0.00001145 57.0
TH3_k127_7290283_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 370.0
TH3_k127_7290283_1 Archaeal holliday junction resolvase (hjc) - - - 0.00000000000000000000000000000000000000000000000001082 185.0
TH3_k127_7296567_0 ATPases associated with a variety of cellular activities K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 319.0
TH3_k127_7296567_1 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 316.0
TH3_k127_7296567_2 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000003184 197.0
TH3_k127_7313347_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000009773 206.0
TH3_k127_7313347_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000004383 194.0
TH3_k127_7355720_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 2.193e-318 990.0
TH3_k127_7355720_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000008947 183.0
TH3_k127_7355720_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000002456 101.0
TH3_k127_7355720_3 Domain of unknown function (DUF1610) K07580 - - 0.00000000000000000006451 89.0
TH3_k127_7355720_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000004221 94.0
TH3_k127_7355720_5 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000000001681 83.0
TH3_k127_7355720_6 FMN binding - - - 0.00004984 51.0
TH3_k127_7373211_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 442.0
TH3_k127_7373211_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 423.0
TH3_k127_7373211_2 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 372.0
TH3_k127_7373211_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007549 254.0
TH3_k127_7373211_4 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000004688 169.0
TH3_k127_7373211_5 CAAX protease self-immunity - - - 0.0000000000000000003821 98.0
TH3_k127_7373211_6 Belongs to the UPF0201 family K09736 - - 0.000000003203 65.0
TH3_k127_7409105_0 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004032 265.0
TH3_k127_7409105_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000002745 226.0
TH3_k127_7409105_2 PHP-associated - - - 0.00000000000000000000000471 115.0
TH3_k127_7409105_3 Ras of Complex, Roc, domain of DAPkinase - - - 0.000000000000000000005859 101.0
TH3_k127_7409105_4 Acetyltransferase (GNAT) domain - - - 0.0000000000001079 79.0
TH3_k127_7409105_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000001249 68.0
TH3_k127_7414801_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000001825 207.0
TH3_k127_7414801_1 - - - - 0.00000000000000000000000000000001969 138.0
TH3_k127_7414801_2 Protein of unknown function DUF131 - - - 0.000005703 54.0
TH3_k127_7436356_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 303.0
TH3_k127_7436356_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000869 199.0
TH3_k127_7436356_2 Acts probably as a methyl group carrier between MttB and either MtbA or MtaA K14084 - - 0.00000000000000000000000000000000000000004974 162.0
TH3_k127_7436356_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000003882 115.0
TH3_k127_7505181_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000001597 189.0
TH3_k127_7505181_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000009762 159.0
TH3_k127_7516141_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 411.0
TH3_k127_7516141_1 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 369.0
TH3_k127_7516141_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004698 278.0
TH3_k127_7516141_3 domain protein K20276 - - 0.000000000005376 76.0
TH3_k127_7516141_4 Belongs to the peptidase S8 family K01361,K08652,K14647 GO:0005575,GO:0005576 3.4.21.110,3.4.21.96 0.0000006788 64.0
TH3_k127_7534767_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000007098 110.0
TH3_k127_7534767_1 Pkd domain containing protein - - - 0.0000000000000000003574 103.0
TH3_k127_7534767_2 Ion channel - - - 0.00000000000001258 78.0
TH3_k127_7553152_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 3.82e-211 671.0
TH3_k127_7553152_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000000000000000004335 172.0
TH3_k127_7553152_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000001993 165.0
TH3_k127_7567883_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 413.0
TH3_k127_7567883_1 Peptidase M14, carboxypeptidase A K05996 - 3.4.17.18 0.000000000000000000000000000000000000000000000000000000000002504 229.0
TH3_k127_7567883_2 Uncharacterised protein family (UPF0179) K09730 - - 0.0000000000000000000000000000000001281 137.0
TH3_k127_7567883_3 Response regulator receiver domain - - - 0.0000000000000000000000001401 115.0
TH3_k127_7567883_4 DNA-binding transcription factor activity K18297 - - 0.000000000000000000002257 104.0
TH3_k127_7567883_5 TPR repeat - - - 0.0000000001032 70.0
TH3_k127_7567883_6 His Kinase A (phosphoacceptor) domain - - - 0.0009232 49.0
TH3_k127_757806_0 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 522.0
TH3_k127_757806_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 353.0
TH3_k127_757806_2 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005728 235.0
TH3_k127_757806_3 OsmC-like protein - - - 0.000000000000000000000000000002209 127.0
TH3_k127_757806_4 - - - - 0.00000000000000000000000000005865 126.0
TH3_k127_7606650_0 hydrolase (HAD superfamily) K07025 - - 0.000000000000000000000000000000000000001032 158.0
TH3_k127_7606650_1 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000343 156.0
TH3_k127_7606650_2 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000009748 139.0
TH3_k127_7622732_0 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 347.0
TH3_k127_7622732_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000336 151.0
TH3_k127_7622732_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000004456 70.0
TH3_k127_7624933_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 588.0
TH3_k127_7624933_1 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000002771 238.0
TH3_k127_7624933_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000005285 171.0
TH3_k127_7624933_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000247 138.0
TH3_k127_7624933_4 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000000000000000000000002348 108.0
TH3_k127_7624933_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000007793 97.0
TH3_k127_7624933_6 Roadblock LC7 family protein K07131 - - 0.0000000000000000005491 91.0
TH3_k127_7626492_0 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000002221 246.0
TH3_k127_7626492_1 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000004365 166.0
TH3_k127_7626492_2 Acetyltransferase (GNAT) domain - - - 0.00001888 50.0
TH3_k127_7653610_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 387.0
TH3_k127_7653610_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 312.0
TH3_k127_7653610_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000006045 76.0
TH3_k127_7678052_0 PFAM Iron-containing alcohol dehydrogenase K00005,K08317 - 1.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000002776 260.0
TH3_k127_7717775_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000006002 181.0
TH3_k127_7717775_1 PFAM GvpD gas vesicle - - - 0.00000000000000000000000000000000513 144.0
TH3_k127_7730157_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000008499 228.0
TH3_k127_7730157_1 peptidase activity, acting on L-amino acid peptides K01179 - 3.2.1.4 0.0000003203 51.0
TH3_k127_7743887_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 463.0
TH3_k127_7743887_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 457.0
TH3_k127_775017_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001795 248.0
TH3_k127_775017_1 - - - - 0.0000000000000000000000000000000000000000000000000001985 194.0
TH3_k127_775017_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000002958 64.0
TH3_k127_7750268_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 8.938e-226 722.0
TH3_k127_7750268_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000236 236.0
TH3_k127_7750268_2 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000000000000143 166.0
TH3_k127_7750268_3 Sodium hydrogen exchanger K11105 - - 0.0000000000000000000000000000000000000002049 166.0
TH3_k127_7750268_4 oligoendopeptidase F - - - 0.000000000000000000000000005622 120.0
TH3_k127_7750268_5 Roadblock LC7 family protein K07131 - - 0.00000000001069 74.0
TH3_k127_7759953_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 413.0
TH3_k127_7759953_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000006091 204.0
TH3_k127_7759953_2 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000004018 102.0
TH3_k127_7871846_0 histidyl-tRNA aminoacylation K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000001971 231.0
TH3_k127_7871846_1 YoaP-like - - - 0.000001154 59.0
TH3_k127_7935202_0 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000003469 185.0
TH3_k127_7935202_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000002076 67.0
TH3_k127_7935202_2 PFAM CBS domain - - - 0.0000001105 64.0
TH3_k127_7976577_0 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000004834 205.0
TH3_k127_7976577_1 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.000000000005563 76.0
TH3_k127_7992306_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 430.0
TH3_k127_7995700_0 4Fe-4S single cluster domain K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 539.0
TH3_k127_7995700_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 383.0
TH3_k127_7995700_2 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000004091 258.0
TH3_k127_7995700_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000001418 83.0
TH3_k127_7995700_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0002578 53.0
TH3_k127_8006533_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 514.0
TH3_k127_8006533_1 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.0000000000000000000000000000000000000000000000000000000000001114 229.0
TH3_k127_8118103_0 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 587.0
TH3_k127_8118103_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 330.0
TH3_k127_8118103_2 GAF domain - - - 0.0000000000000000000000000000000000000000000000125 191.0
TH3_k127_8118103_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000106 75.0
TH3_k127_8125042_0 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000000000000000000000000000000000012 208.0
TH3_k127_8125042_1 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000004822 114.0
TH3_k127_8125042_2 - - - - 0.000000000000000000000008472 108.0
TH3_k127_8125042_3 - - - - 0.000000000001043 74.0
TH3_k127_8144022_0 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 292.0
TH3_k127_8144022_1 translation initiation factor 2 subunit alpha K03237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009008 289.0
TH3_k127_8144022_10 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000192 89.0
TH3_k127_8144022_11 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000001654 71.0
TH3_k127_8144022_12 - - - - 0.0000000003266 72.0
TH3_k127_8144022_13 Large extracellular alpha-helical protein K06894 - - 0.000000002379 66.0
TH3_k127_8144022_14 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00000645 52.0
TH3_k127_8144022_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000001416 246.0
TH3_k127_8144022_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000335 194.0
TH3_k127_8144022_4 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000002699 159.0
TH3_k127_8144022_5 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000001188 136.0
TH3_k127_8144022_6 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000006005 137.0
TH3_k127_8144022_7 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000006662 128.0
TH3_k127_8144022_8 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000000001255 121.0
TH3_k127_8144022_9 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000008094 93.0
TH3_k127_816594_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.000000000000000000000000000000000000000000000000000001408 201.0
TH3_k127_816594_1 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000001048 160.0
TH3_k127_816594_2 Protein of unknown function (DUF835) - - - 0.0004369 53.0
TH3_k127_8283400_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 508.0
TH3_k127_8283400_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003249 273.0
TH3_k127_8283400_2 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000000005014 211.0
TH3_k127_8283400_3 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000001824 145.0
TH3_k127_8283400_4 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000002973 97.0
TH3_k127_8283400_5 binds to the 23S rRNA K02922 - - 0.00000000000000000381 84.0
TH3_k127_8283400_6 - - - - 0.0000103 53.0
TH3_k127_829421_0 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000002687 106.0
TH3_k127_829421_1 Belongs to the peptidase S8 family - - - 0.000000000000000000006757 102.0
TH3_k127_829421_2 aminopeptidase - - - 0.000000004145 70.0
TH3_k127_8348676_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000009202 217.0
TH3_k127_8348676_1 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000000005618 121.0
TH3_k127_8348676_2 FAD dependent oxidoreductase - - - 0.000000001482 61.0
TH3_k127_8348676_3 PFAM UBA THIF-type NAD FAD binding K21029 - 2.7.7.80 0.00000003725 57.0
TH3_k127_8375859_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001869 260.0
TH3_k127_8375859_1 Pfam:DUF552 K09152 - - 0.000000000000000000000000000846 117.0
TH3_k127_8375859_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000002887 76.0
TH3_k127_8408767_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 432.0
TH3_k127_8408767_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 295.0
TH3_k127_8408767_2 CheC-like family K03410 - - 0.00000000000000000000000000000000106 138.0
TH3_k127_8408767_3 Chemotaxis protein cheW K03408 - - 0.00000000000000000000000000000003875 135.0
TH3_k127_8408767_4 Chemotaxis protein cheY K03413 - - 0.0000000000000000000000000000001432 127.0
TH3_k127_8408767_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000009697 106.0
TH3_k127_8415007_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.173e-263 829.0
TH3_k127_8415007_1 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 493.0
TH3_k127_8415007_2 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000001737 220.0
TH3_k127_8415007_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000003377 107.0
TH3_k127_8503313_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000105 224.0
TH3_k127_8503313_1 Double zinc ribbon - - - 0.000000279 63.0
TH3_k127_8523543_0 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000007585 170.0
TH3_k127_8523543_1 tryptophanyl-tRNA aminoacylation K01867 - 6.1.1.2 0.000008758 48.0
TH3_k127_8545420_0 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006331 282.0
TH3_k127_8545420_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000297 171.0
TH3_k127_8625346_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001181 243.0
TH3_k127_8625346_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000001869 148.0
TH3_k127_8632686_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000141 263.0
TH3_k127_8632686_1 Ras-related protein Rab-37-like K07913,K07914 GO:0000166,GO:0000323,GO:0001775,GO:0001882,GO:0001883,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002790,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005766,GO:0005768,GO:0005773,GO:0005774,GO:0005793,GO:0005886,GO:0006810,GO:0006887,GO:0006904,GO:0006955,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0008021,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0012505,GO:0012506,GO:0015031,GO:0015833,GO:0016020,GO:0016192,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0017157,GO:0019001,GO:0022406,GO:0023052,GO:0030133,GO:0030141,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0032482,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032879,GO:0032940,GO:0033036,GO:0034613,GO:0035556,GO:0035577,GO:0035579,GO:0035639,GO:0036094,GO:0036230,GO:0042119,GO:0042581,GO:0042582,GO:0042886,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043299,GO:0043312,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044464,GO:0045055,GO:0045184,GO:0045202,GO:0045321,GO:0046903,GO:0048278,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051179,GO:0051234,GO:0051640,GO:0051641,GO:0051716,GO:0060627,GO:0065007,GO:0070382,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0072659,GO:0097159,GO:0097367,GO:0097458,GO:0097708,GO:0098588,GO:0098793,GO:0098805,GO:0098852,GO:0099503,GO:0140029,GO:0140056,GO:1901265,GO:1901363,GO:1903530,GO:1990778 - 0.00000000000000001561 87.0
TH3_k127_8632686_2 Hint domain - - - 0.00000000000000008681 96.0
TH3_k127_8632686_3 OmpA family - - - 0.0000000001413 76.0
TH3_k127_8651909_0 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000001158 181.0
TH3_k127_8651909_1 Oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000003295 153.0
TH3_k127_8651909_2 Phosphatidylserine decarboxylase K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.0000000000000000000000000000000000001607 148.0
TH3_k127_8651909_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000005324 78.0
TH3_k127_8652041_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 367.0
TH3_k127_8652041_1 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000004243 158.0
TH3_k127_8652041_2 glycosyl transferase group 1 - - - 0.00000000000000000001286 94.0
TH3_k127_8652041_3 EamA-like transporter family - - - 0.0000000000006904 79.0
TH3_k127_8652041_4 Signal transduction histidine kinase - - - 0.00000006489 53.0
TH3_k127_866283_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000001848 130.0
TH3_k127_8667561_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 321.0
TH3_k127_8667561_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000002156 265.0
TH3_k127_8667561_2 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity) K04484 - - 0.000000000000000000000000000000000000000000000001531 180.0
TH3_k127_8667561_3 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000002772 112.0
TH3_k127_8668187_0 DNA polymerase type-B family K02319 - 2.7.7.7 2.59e-260 840.0
TH3_k127_8668187_1 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 466.0
TH3_k127_8668187_2 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002307 259.0
TH3_k127_8668187_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000001461 169.0
TH3_k127_8668187_4 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000001936 161.0
TH3_k127_8743952_0 Protein of unknown function (DUF1616) - - - 0.00002731 55.0
TH3_k127_8743952_1 MacB-like periplasmic core domain K02004 - - 0.0002263 53.0
TH3_k127_8771892_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 407.0
TH3_k127_8771892_1 PP-loop family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 312.0
TH3_k127_8771892_2 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000001522 79.0
TH3_k127_8797692_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 406.0
TH3_k127_8797692_1 DnaB-like helicase C terminal domain - - - 0.00000000002488 70.0
TH3_k127_881553_0 Flavodoxin - - - 0.00000000000000000000000000000000000000000001588 166.0
TH3_k127_881553_1 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000001057 112.0
TH3_k127_881553_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000001579 98.0
TH3_k127_881553_3 Acetyltransferase (GNAT) domain - - - 0.00000008084 56.0
TH3_k127_8828198_0 MCM OB domain K10726 - - 1.326e-216 693.0
TH3_k127_8828198_1 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 498.0
TH3_k127_8828198_10 Pfam:DUF1628 - - - 0.00001337 54.0
TH3_k127_8828198_2 Rad51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 325.0
TH3_k127_8828198_3 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001713 246.0
TH3_k127_8828198_4 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000001956 172.0
TH3_k127_8828198_5 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000002319 149.0
TH3_k127_8828198_6 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000001415 136.0
TH3_k127_8828198_7 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000005603 109.0
TH3_k127_8828198_8 RDD family - - - 0.000000002502 64.0
TH3_k127_8828198_9 NMD3 family K07562 - - 0.0000005074 56.0
TH3_k127_8828274_0 PFAM sodium calcium exchanger K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002974 268.0
TH3_k127_8828274_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003569 253.0
TH3_k127_8828274_2 COG0477 Permeases of the major facilitator superfamily K08153 - - 0.0002922 49.0
TH3_k127_8833339_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 536.0
TH3_k127_8833339_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.000000000000000001476 87.0
TH3_k127_8833339_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000001195 87.0
TH3_k127_8833339_3 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.0007132 48.0
TH3_k127_8852608_0 A-macroglobulin complement component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 332.0
TH3_k127_8859977_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 474.0
TH3_k127_8859977_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 395.0
TH3_k127_8901384_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 380.0
TH3_k127_8901384_1 glucose sorbosone - - - 0.00000000000000000005943 106.0
TH3_k127_8901384_2 Acetyltransferase (GNAT) family - - - 0.00000002173 66.0
TH3_k127_8912868_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 605.0
TH3_k127_8912868_1 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 471.0
TH3_k127_8913569_0 Heat shock 70 kDa protein K04043 - - 1.929e-268 839.0
TH3_k127_8913569_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 425.0
TH3_k127_8913569_10 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000543 243.0
TH3_k127_8913569_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000008672 246.0
TH3_k127_8913569_12 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000002425 235.0
TH3_k127_8913569_13 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000001091 231.0
TH3_k127_8913569_14 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000006038 226.0
TH3_k127_8913569_15 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000003026 212.0
TH3_k127_8913569_16 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000001353 191.0
TH3_k127_8913569_17 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000002141 193.0
TH3_k127_8913569_18 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000004026 174.0
TH3_k127_8913569_19 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000003487 175.0
TH3_k127_8913569_2 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 385.0
TH3_k127_8913569_20 - - - - 0.0000000000000000000000000000485 127.0
TH3_k127_8913569_21 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000001153 118.0
TH3_k127_8913569_22 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000005533 116.0
TH3_k127_8913569_23 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.0000000000000000000000001059 117.0
TH3_k127_8913569_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 372.0
TH3_k127_8913569_4 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 376.0
TH3_k127_8913569_5 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 346.0
TH3_k127_8913569_6 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 317.0
TH3_k127_8913569_7 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 312.0
TH3_k127_8913569_8 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 297.0
TH3_k127_8913569_9 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002286 281.0
TH3_k127_8942280_0 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 415.0
TH3_k127_8942280_1 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002159 286.0
TH3_k127_8942280_2 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000002214 247.0
TH3_k127_8942280_3 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.000002293 52.0
TH3_k127_8988402_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 316.0
TH3_k127_8988402_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000002684 192.0
TH3_k127_8988402_2 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000006727 157.0
TH3_k127_8992873_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 465.0
TH3_k127_8992873_1 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000000000000000001064 171.0
TH3_k127_8992873_2 PFAM Thioredoxin K03671 - - 0.0000000000000000000000000000001146 127.0
TH3_k127_8992873_3 Carbohydrate binding module (family 35) - - - 0.0009029 50.0
TH3_k127_9049756_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 546.0
TH3_k127_9049756_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001217 271.0
TH3_k127_9049756_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000828 243.0
TH3_k127_9049756_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000003346 212.0
TH3_k127_9049756_4 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007039 207.0
TH3_k127_9049756_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000002007 186.0
TH3_k127_9049756_6 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000008737 161.0
TH3_k127_9049756_7 Ribbon-helix-helix protein, copG family K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000001038 115.0
TH3_k127_9049756_8 cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000001168 89.0
TH3_k127_9049756_9 VIT family - - - 0.0001028 47.0
TH3_k127_9057967_0 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000001821 243.0
TH3_k127_9057967_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000001284 213.0
TH3_k127_9086085_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000001072 198.0
TH3_k127_9086085_1 PAP2 superfamily - - - 0.00000000000000001625 93.0
TH3_k127_9086085_2 TIGRFAM MoaD family protein K03636 - - 0.0000000000006021 73.0
TH3_k127_9086085_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000001622 72.0
TH3_k127_9108361_0 - - - - 0.00000000004285 74.0
TH3_k127_9108361_1 - - - - 0.0000000001853 71.0
TH3_k127_9136222_0 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000578 125.0
TH3_k127_9136222_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000003874 123.0
TH3_k127_9136222_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000008094 118.0
TH3_k127_9189615_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000000000001442 227.0
TH3_k127_9189615_1 Phenazine biosynthesis protein phzf family - - - 0.00000000000000000000000000000000000000000000007789 186.0
TH3_k127_9189615_2 protein conserved in archaea - - - 0.0000000001938 66.0
TH3_k127_9189615_3 Bacterial periplasmic substrate-binding proteins - - - 0.000009139 55.0
TH3_k127_9191250_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 504.0
TH3_k127_9191250_1 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005082 270.0
TH3_k127_9191250_2 Fcf1 K07158 - - 0.0000000000000000000002788 100.0
TH3_k127_9248689_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 485.0
TH3_k127_9248689_1 PFAM TPR repeat-containing protein - - - 0.000064 54.0
TH3_k127_925676_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 536.0
TH3_k127_925676_1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000004925 163.0
TH3_k127_9271230_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.193e-194 622.0
TH3_k127_9271230_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003464 297.0
TH3_k127_9314794_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006282 254.0
TH3_k127_9314794_1 aminopeptidase activity K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000002126 239.0
TH3_k127_935532_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 330.0
TH3_k127_935532_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000119 251.0
TH3_k127_935532_10 PFAM Forkhead-associated protein - - - 0.00000000000000000001183 105.0
TH3_k127_935532_11 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000004674 86.0
TH3_k127_935532_2 DNA polymerase alpha chain like domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000005926 235.0
TH3_k127_935532_3 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.00000000000000000000000000000000000000000000000000000000006199 214.0
TH3_k127_935532_4 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000003369 209.0
TH3_k127_935532_5 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000002098 208.0
TH3_k127_935532_6 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000001436 201.0
TH3_k127_935532_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000001463 182.0
TH3_k127_935532_8 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000001578 170.0
TH3_k127_935532_9 hmm pf03415 K08587 - 3.4.22.8 0.00000000000000000000000005072 122.0
TH3_k127_937002_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000002509 198.0
TH3_k127_937002_1 PFAM GHMP kinase K06982 - 2.7.1.169 0.0000000000000000000000000000000000000000001384 170.0
TH3_k127_937002_2 Protein of unknown function (DUF357) K09728 - - 0.00000000000000000000000000007288 116.0
TH3_k127_9383517_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 597.0
TH3_k127_9383517_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 419.0
TH3_k127_9383517_10 homolog of PrgY (pheromone shutdown protein) - - - 0.00000000000000000000000000001527 128.0
TH3_k127_9383517_11 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000004613 132.0
TH3_k127_9383517_12 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000153 96.0
TH3_k127_9383517_13 PFAM Rhomboid family protein K07059 - - 0.00000000000000000005933 103.0
TH3_k127_9383517_14 COG5598 Trimethylamine corrinoid methyltransferase K14083 - 2.1.1.250 0.000000000000001078 87.0
TH3_k127_9383517_15 translation initiation factor activity K03680 - - 0.0000000000014 78.0
TH3_k127_9383517_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 366.0
TH3_k127_9383517_3 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 310.0
TH3_k127_9383517_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 288.0
TH3_k127_9383517_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000002539 245.0
TH3_k127_9383517_6 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000001173 221.0
TH3_k127_9383517_7 archaeal Zn-finger protein - - - 0.0000000000000000000000000000000000000004271 156.0
TH3_k127_9383517_8 Methyltransferase domain K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000001216 149.0
TH3_k127_9383517_9 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000005091 147.0
TH3_k127_9385853_0 ribonuclease activity - - - 0.000000000000000000000000000000000000000009191 157.0
TH3_k127_9385853_1 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000000006374 120.0
TH3_k127_9385853_2 RES - - - 0.000000000000000000000006339 106.0
TH3_k127_9385853_3 toxin-antitoxin pair type II binding - - - 0.000000000007807 69.0
TH3_k127_9479879_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.575e-287 891.0
TH3_k127_948744_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 411.0
TH3_k127_948744_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 391.0
TH3_k127_948744_10 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.00000000001896 66.0
TH3_k127_948744_11 binds to the 23S rRNA K02921 - - 0.0000000000704 65.0
TH3_k127_948744_12 Transcription factor Pcc1 K09741 - - 0.000000696 55.0
TH3_k127_948744_13 - - - - 0.0001407 48.0
TH3_k127_948744_2 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003929 275.0
TH3_k127_948744_3 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006869 270.0
TH3_k127_948744_4 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 265.0
TH3_k127_948744_5 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000002124 242.0
TH3_k127_948744_6 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000138 133.0
TH3_k127_948744_7 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.00000000000000000000000009345 119.0
TH3_k127_948744_8 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000003915 96.0
TH3_k127_948744_9 - - - - 0.00000000000002991 76.0
TH3_k127_9503950_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 7.941e-232 773.0
TH3_k127_9503950_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 413.0
TH3_k127_9503950_2 4Fe-4S single cluster domain K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 372.0
TH3_k127_9503950_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000006713 263.0
TH3_k127_9503950_4 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000000000000000000000006435 201.0
TH3_k127_9503950_5 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001033 90.0
TH3_k127_9503950_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000077 80.0
TH3_k127_9547372_0 Diphthamide K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000005851 273.0
TH3_k127_9547372_1 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003761 201.0
TH3_k127_9552662_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000007944 162.0
TH3_k127_9552662_1 domain protein K13735,K15125,K20276 - - 0.0000000000000000003175 103.0
TH3_k127_9589045_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 578.0
TH3_k127_9589045_1 Laminin G domain - - - 0.00000004191 66.0
TH3_k127_9589045_2 Acetyltransferase (GNAT) domain - - - 0.0002447 49.0
TH3_k127_9594868_0 KH domain K07041 - - 1.109e-268 840.0
TH3_k127_9594868_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000003155 173.0
TH3_k127_9594868_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000001398 171.0
TH3_k127_9620672_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000003249 232.0
TH3_k127_9620672_1 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.000000000000000000000000000000000000003286 154.0
TH3_k127_9626631_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000004224 156.0
TH3_k127_9626631_1 MoaE protein K21142 - 2.8.1.12 0.000000000000001451 79.0
TH3_k127_9626631_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000013 86.0
TH3_k127_9634146_0 aspartate carbamoyltransferase activity K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 390.0
TH3_k127_9634146_1 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 325.0
TH3_k127_9634146_2 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001757 281.0
TH3_k127_9634146_3 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000006663 193.0
TH3_k127_9634146_4 AAA domain - - - 0.000000000000000000000000000000000000000001293 166.0
TH3_k127_9634146_5 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000001787 162.0
TH3_k127_9634146_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000003847 122.0
TH3_k127_9634146_7 4Fe-4S dicluster domain - - - 0.00000000000000000002734 94.0
TH3_k127_9634146_8 - K21029 - 2.7.7.80 0.00000004278 58.0
TH3_k127_9679327_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 535.0
TH3_k127_9685788_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003664 291.0
TH3_k127_9685788_1 ATPases associated with a variety of cellular activities K16784,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000006849 241.0
TH3_k127_9685788_2 ATP-binding protein K16786 - - 0.00000000000000000000000000000000000000000000000000000000000000001428 234.0
TH3_k127_9685788_3 - - - - 0.00001437 56.0
TH3_k127_9686702_0 TIGRFAM Small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 404.0
TH3_k127_9686702_1 - - - - 0.0000000000000003712 81.0
TH3_k127_9716359_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 384.0
TH3_k127_9716359_1 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000001803 174.0
TH3_k127_9720061_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 473.0
TH3_k127_9720061_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 334.0
TH3_k127_9720061_2 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000001036 212.0
TH3_k127_9720061_3 Acetyltransferase (GNAT) domain - - - 0.0000000000001035 81.0
TH3_k127_9760537_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 334.0
TH3_k127_9760537_1 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000002053 175.0
TH3_k127_9760537_2 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.0000000001013 64.0
TH3_k127_9760537_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0006895 47.0
TH3_k127_9798211_0 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007396 295.0
TH3_k127_9798211_1 transferase activity, transferring glycosyl groups K01186,K01371,K20276 - 3.2.1.18,3.4.22.38 0.000008978 59.0
TH3_k127_9844431_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 4.037e-284 900.0
TH3_k127_9844431_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 304.0