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Overview

ID MAG03936
Name TH3_bin.18
Sample SMP0102
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus UBA6898
Species
Assembly information
Completeness (%) 70.91
Contamination (%) 3.28
GC content (%) 52.0
N50 (bp) 9,219
Genome size (bp) 2,207,363

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2207

Gene name Description KEGG GOs EC E-value Score Sequence
TH3_k127_1011280_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1639.0
TH3_k127_1011280_1 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 398.0
TH3_k127_1011280_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 385.0
TH3_k127_1011280_3 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000226 244.0
TH3_k127_1011280_4 HNH nucleases K07451 - - 0.000000000000000000000000000000000000000000000000000000000000000002385 233.0
TH3_k127_1011280_5 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000002476 146.0
TH3_k127_1011280_6 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000008291 102.0
TH3_k127_1011280_7 secretion protein K01993 - - 0.000000000000000003453 96.0
TH3_k127_1011280_8 transcriptional regulator - - - 0.00000000000000001189 91.0
TH3_k127_1011280_9 Belongs to the 'phage' integrase family - - - 0.0000000000001234 73.0
TH3_k127_1021525_0 FAD binding domain K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 605.0
TH3_k127_1021525_1 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 527.0
TH3_k127_1021525_2 GHKL domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000002338 192.0
TH3_k127_1029778_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 3.754e-258 824.0
TH3_k127_1029778_1 CobQ CobB MinD ParA nucleotide binding K04562 - - 0.0000000000000000000004188 102.0
TH3_k127_1032221_0 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 363.0
TH3_k127_1032221_1 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000008299 155.0
TH3_k127_1032221_2 TIGRFAM methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.0000000000000000000000000000000000000007964 153.0
TH3_k127_1032221_3 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000004461 149.0
TH3_k127_106891_0 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000003094 241.0
TH3_k127_106891_1 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000001186 184.0
TH3_k127_106891_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000008625 147.0
TH3_k127_106891_3 - - - - 0.0000000000000000000000000279 113.0
TH3_k127_1081388_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 505.0
TH3_k127_1081388_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 479.0
TH3_k127_1081388_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001164 265.0
TH3_k127_1081388_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000003005 188.0
TH3_k127_1081388_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000056 151.0
TH3_k127_1148650_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 516.0
TH3_k127_1148650_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 512.0
TH3_k127_1148650_2 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 377.0
TH3_k127_1148650_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 337.0
TH3_k127_1148650_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 312.0
TH3_k127_1148650_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000001021 251.0
TH3_k127_1148650_6 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000002246 226.0
TH3_k127_1148650_7 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000132 156.0
TH3_k127_1148650_8 nucleotidyltransferase activity K07075 - - 0.000000000000000000000002424 110.0
TH3_k127_1148650_9 Transposase, Mutator family - - - 0.00000001074 62.0
TH3_k127_1309322_0 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 307.0
TH3_k127_1309322_1 tail collar domain protein K01406,K21449 - 3.4.24.40 0.00000000000000005754 94.0
TH3_k127_1320317_0 phenylalanine-tRNA ligase activity K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 586.0
TH3_k127_1320317_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001819 285.0
TH3_k127_1320317_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000001341 171.0
TH3_k127_1320317_3 mercury ion transmembrane transporter activity K07213 - - 0.00000000000005541 75.0
TH3_k127_1321914_0 Domain of unknown function (DUF1957) K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 528.0
TH3_k127_1321914_1 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 383.0
TH3_k127_1321914_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000001898 214.0
TH3_k127_1394449_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 608.0
TH3_k127_1394449_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 576.0
TH3_k127_1394449_10 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000008184 159.0
TH3_k127_1394449_11 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000002386 144.0
TH3_k127_1394449_12 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000001775 132.0
TH3_k127_1394449_14 Polymer-forming cytoskeletal - - - 0.00000000000000002315 86.0
TH3_k127_1394449_15 - - - - 0.000000000648 65.0
TH3_k127_1394449_2 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 464.0
TH3_k127_1394449_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 333.0
TH3_k127_1394449_4 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 321.0
TH3_k127_1394449_5 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 310.0
TH3_k127_1394449_6 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008284 280.0
TH3_k127_1394449_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000009393 254.0
TH3_k127_1394449_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000001679 243.0
TH3_k127_1394449_9 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000006258 215.0
TH3_k127_1394656_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 317.0
TH3_k127_1394656_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 297.0
TH3_k127_1394656_2 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000002314 194.0
TH3_k127_1394656_3 Translation initiation factor IF-3, N-terminal domain K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000001362 185.0
TH3_k127_1394656_4 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000000000001057 156.0
TH3_k127_1395737_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.128e-234 750.0
TH3_k127_1395737_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 366.0
TH3_k127_142484_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.443e-225 709.0
TH3_k127_142484_1 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 555.0
TH3_k127_142484_10 Sulfurtransferase DndC K19170 - - 0.000000061 58.0
TH3_k127_142484_11 AAA-like domain - - - 0.0000001295 57.0
TH3_k127_142484_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 530.0
TH3_k127_142484_3 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 329.0
TH3_k127_142484_4 COG0175 3-phosphoadenosine 5-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K19170 - - 0.00000000000000000000000000000000000000000000000000000000000000000002878 236.0
TH3_k127_142484_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000001731 201.0
TH3_k127_142484_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000000001249 203.0
TH3_k127_142484_7 HNH endonuclease K07454 - - 0.0000000000000000000000002719 110.0
TH3_k127_142484_8 sulfate reduction K19170 - - 0.000000000000003607 81.0
TH3_k127_142484_9 SEC-C Motif Domain Protein - - - 0.0000000003752 66.0
TH3_k127_1448133_0 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000003291 235.0
TH3_k127_1448133_1 - - - - 0.0000000000000000000000000000000000000000000000000000000002382 214.0
TH3_k127_1448133_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000006275 95.0
TH3_k127_1484584_0 General secretory system II, protein E domain protein K02652 - - 2.651e-213 679.0
TH3_k127_1484584_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 552.0
TH3_k127_1484584_10 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.00000000000000000000000000000000000000004453 155.0
TH3_k127_1484584_11 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000004623 108.0
TH3_k127_1484584_13 - - - - 0.0006968 44.0
TH3_k127_1484584_2 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 462.0
TH3_k127_1484584_3 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 379.0
TH3_k127_1484584_4 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 350.0
TH3_k127_1484584_5 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 303.0
TH3_k127_1484584_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000005266 240.0
TH3_k127_1484584_7 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000007543 231.0
TH3_k127_1484584_8 Mo-molybdopterin cofactor metabolic process K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000218 228.0
TH3_k127_1484584_9 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000001331 183.0
TH3_k127_1495471_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 301.0
TH3_k127_1495471_1 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005496 274.0
TH3_k127_1495471_2 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000004678 221.0
TH3_k127_1495471_3 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000006485 120.0
TH3_k127_1495471_4 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000008292 85.0
TH3_k127_1510960_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.217e-318 992.0
TH3_k127_1510960_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 585.0
TH3_k127_1510960_10 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000001572 216.0
TH3_k127_1510960_11 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000001258 86.0
TH3_k127_1510960_12 - - - - 0.00000002536 60.0
TH3_k127_1510960_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 485.0
TH3_k127_1510960_3 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 462.0
TH3_k127_1510960_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 383.0
TH3_k127_1510960_5 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 368.0
TH3_k127_1510960_6 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 310.0
TH3_k127_1510960_7 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001434 289.0
TH3_k127_1510960_8 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002633 278.0
TH3_k127_1510960_9 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000001051 276.0
TH3_k127_1536894_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 478.0
TH3_k127_1536894_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 389.0
TH3_k127_1536894_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000001477 235.0
TH3_k127_1536894_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000008836 101.0
TH3_k127_1536894_4 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000002194 72.0
TH3_k127_1561349_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 1.986e-232 722.0
TH3_k127_1561349_1 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000006165 183.0
TH3_k127_1561349_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000317 176.0
TH3_k127_1561349_3 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000001949 147.0
TH3_k127_1565262_0 Chain length determinant protein K16554 - - 2.801e-199 644.0
TH3_k127_1565262_1 ABC transporter transmembrane region K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 526.0
TH3_k127_1565262_11 Psort location Cytoplasmic, score 8.87 - - - 0.00003064 52.0
TH3_k127_1565262_12 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0009869 44.0
TH3_k127_1565262_2 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 530.0
TH3_k127_1565262_3 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 503.0
TH3_k127_1565262_4 domain protein K14194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 390.0
TH3_k127_1565262_5 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 298.0
TH3_k127_1565262_6 export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 292.0
TH3_k127_1565262_7 Putative beta-barrel porin 2 K20920 - - 0.0000000000000000000000000000000000000000000000002488 196.0
TH3_k127_1565262_8 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000002663 184.0
TH3_k127_1621940_0 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 522.0
TH3_k127_1621940_1 Signal transduction histidine kinase, nitrogen specific K07708 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000002425 147.0
TH3_k127_1621940_2 Aspartyl-tRNA amidotransferase K09117 - - 0.000000000000000000000001354 108.0
TH3_k127_1621940_3 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000002653 91.0
TH3_k127_1631845_0 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 591.0
TH3_k127_1631845_1 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 302.0
TH3_k127_1631845_10 Belongs to the P(II) protein family K04751 - - 0.000002231 52.0
TH3_k127_1631845_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000515 276.0
TH3_k127_1631845_3 Protein of unknown function (DUF1646) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002802 257.0
TH3_k127_1631845_4 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000001038 205.0
TH3_k127_1631845_5 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000001068 171.0
TH3_k127_1631845_6 - - - - 0.000000000000000000000000000000000000000002679 165.0
TH3_k127_1631845_7 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000003887 110.0
TH3_k127_1631845_8 GAF domain K02584 - - 0.000000003175 61.0
TH3_k127_1631845_9 Protein of unknown function (DUF1646) - - - 0.000000004259 62.0
TH3_k127_1639169_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.616e-230 723.0
TH3_k127_1639169_1 GAF domain K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 578.0
TH3_k127_1639169_2 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000001016 214.0
TH3_k127_1639169_3 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000001546 189.0
TH3_k127_1639169_4 Diadenylate cyclase - - - 0.000000000000000001188 88.0
TH3_k127_1657367_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0 1056.0
TH3_k127_1657367_1 alcohol dehydrogenase - - - 5.529e-259 818.0
TH3_k127_1657367_10 Glycosyltransferase like family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001834 282.0
TH3_k127_1657367_11 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003625 272.0
TH3_k127_1657367_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005664 254.0
TH3_k127_1657367_13 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000007215 229.0
TH3_k127_1657367_14 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000002261 190.0
TH3_k127_1657367_15 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000000000000000000000000005083 179.0
TH3_k127_1657367_16 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000003307 172.0
TH3_k127_1657367_17 Methyltransferase domain - - - 0.000000000000000000000000000000000000004911 156.0
TH3_k127_1657367_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 476.0
TH3_k127_1657367_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 441.0
TH3_k127_1657367_4 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 425.0
TH3_k127_1657367_5 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 407.0
TH3_k127_1657367_6 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 397.0
TH3_k127_1657367_8 PFAM NAD dependent epimerase dehydratase family K01784,K17947 - 5.1.3.2,5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 317.0
TH3_k127_1657367_9 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 302.0
TH3_k127_1675079_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 545.0
TH3_k127_1675079_1 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000002675 170.0
TH3_k127_1675079_2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000004416 168.0
TH3_k127_1675079_3 Fibronectin type 3 domain - - - 0.0000000000000000000000007643 116.0
TH3_k127_1675079_4 Helix-turn-helix XRE-family like proteins - - - 0.0005123 43.0
TH3_k127_1700017_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1069.0
TH3_k127_1700017_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.277e-214 675.0
TH3_k127_1700017_10 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000003418 196.0
TH3_k127_1700017_11 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000004271 160.0
TH3_k127_1700017_12 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000002011 165.0
TH3_k127_1700017_13 domain, Protein - - - 0.000000000000000000001309 109.0
TH3_k127_1700017_14 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000002427 64.0
TH3_k127_1700017_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 549.0
TH3_k127_1700017_3 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 411.0
TH3_k127_1700017_4 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 323.0
TH3_k127_1700017_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001659 276.0
TH3_k127_1700017_6 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004781 281.0
TH3_k127_1700017_7 Tetratricopeptide repeat K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000007684 243.0
TH3_k127_1700017_8 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000115 228.0
TH3_k127_1700017_9 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000002726 227.0
TH3_k127_1700995_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 484.0
TH3_k127_1700995_1 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 389.0
TH3_k127_1700995_2 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001701 269.0
TH3_k127_1700995_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000002746 216.0
TH3_k127_1700995_4 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000005895 205.0
TH3_k127_1700995_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000004029 201.0
TH3_k127_1732363_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 394.0
TH3_k127_1732363_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000002094 200.0
TH3_k127_1732363_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000002912 126.0
TH3_k127_1732363_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000986 91.0
TH3_k127_1788657_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1084.0
TH3_k127_1788657_1 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 500.0
TH3_k127_1788657_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 320.0
TH3_k127_1788657_3 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 292.0
TH3_k127_1788657_4 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000002502 241.0
TH3_k127_1788657_5 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000002261 200.0
TH3_k127_1788657_6 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000001871 157.0
TH3_k127_1788657_7 response regulator - - - 0.00000000000000000000000000000000000002232 156.0
TH3_k127_1788657_8 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000000000006781 126.0
TH3_k127_1788657_9 Regulatory protein, FmdB family - - - 0.000005307 51.0
TH3_k127_1798212_0 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 381.0
TH3_k127_1798212_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000001838 209.0
TH3_k127_1798212_2 endonuclease III K03575 - - 0.0000000000000000000000000000000000000001128 158.0
TH3_k127_1798212_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000001075 123.0
TH3_k127_1810958_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 611.0
TH3_k127_1810958_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 418.0
TH3_k127_1810958_2 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 385.0
TH3_k127_1810958_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 302.0
TH3_k127_1810958_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000001477 241.0
TH3_k127_1810958_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000005398 121.0
TH3_k127_1810958_6 HTH-like domain K07497 - - 0.000000000000000002269 89.0
TH3_k127_1810958_7 EP4 subtype prostaglandin E2 receptor binding - - - 0.00000257 50.0
TH3_k127_1813967_0 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 533.0
TH3_k127_1813967_1 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 357.0
TH3_k127_1813967_2 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000876 241.0
TH3_k127_1813967_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007494 241.0
TH3_k127_1813967_4 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000002062 162.0
TH3_k127_1813967_5 phosphorelay signal transduction system - - - 0.0000000000000000268 85.0
TH3_k127_1848159_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 552.0
TH3_k127_1848159_1 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000971 207.0
TH3_k127_1848159_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000001657 102.0
TH3_k127_1848159_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000001991 81.0
TH3_k127_1882391_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 449.0
TH3_k127_1882391_1 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 336.0
TH3_k127_1882391_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000652 189.0
TH3_k127_1958335_0 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 603.0
TH3_k127_1958335_1 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 456.0
TH3_k127_1958335_2 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 243.0
TH3_k127_1958335_3 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000008045 227.0
TH3_k127_1958335_4 NADH dehydrogenase - - - 0.000000000000000000000000000000000000001319 150.0
TH3_k127_1988335_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182,K16239,K16874 - 4.1.1.61,4.1.1.98 1.131e-212 670.0
TH3_k127_1988335_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 457.0
TH3_k127_1988335_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 407.0
TH3_k127_1988335_3 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 343.0
TH3_k127_1988335_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 312.0
TH3_k127_1988335_5 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000003194 123.0
TH3_k127_1988335_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000002584 116.0
TH3_k127_1988335_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000563 112.0
TH3_k127_1988335_8 dehydrogenase - - - 0.0001614 44.0
TH3_k127_200123_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 283.0
TH3_k127_200123_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000001089 164.0
TH3_k127_200123_2 - - - - 0.00000000000000000000000000000001613 131.0
TH3_k127_200123_3 Protein export membrane protein K07003 - - 0.00000000000000000000000000001548 133.0
TH3_k127_2067585_0 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 571.0
TH3_k127_2067585_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 467.0
TH3_k127_2067585_2 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 420.0
TH3_k127_2067585_3 cytochrome c biogenesis protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 369.0
TH3_k127_2067585_4 ABC transporter, permease protein K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 337.0
TH3_k127_2067585_5 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000001574 89.0
TH3_k127_2067585_6 MORN repeat variant - - - 0.00013 51.0
TH3_k127_2120999_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 3.174e-236 742.0
TH3_k127_2120999_1 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 379.0
TH3_k127_2120999_10 Protein of unknown function (DUF4079) - - - 0.0000001258 59.0
TH3_k127_2120999_11 radical SAM domain protein - - - 0.0000004147 56.0
TH3_k127_2120999_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 333.0
TH3_k127_2120999_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 336.0
TH3_k127_2120999_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001243 284.0
TH3_k127_2120999_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001368 272.0
TH3_k127_2120999_6 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000001668 233.0
TH3_k127_2120999_7 PFAM Nitroreductase - - - 0.00000000000000000000005135 99.0
TH3_k127_2120999_8 Rubrerythrin - - - 0.000000000000000000001131 100.0
TH3_k127_2120999_9 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000001691 59.0
TH3_k127_2133207_0 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 393.0
TH3_k127_2133207_1 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 366.0
TH3_k127_2133207_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 309.0
TH3_k127_2133207_3 O COG3187 Heat shock protein - - - 0.00000000000000000000000001736 126.0
TH3_k127_2133207_4 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000000244 107.0
TH3_k127_215811_0 Belongs to the bacterial glucokinase family K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 436.0
TH3_k127_215811_1 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 429.0
TH3_k127_215811_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000112 89.0
TH3_k127_215811_3 YMGG-like Gly-zipper - - - 0.000003766 56.0
TH3_k127_216042_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 410.0
TH3_k127_216042_1 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 309.0
TH3_k127_2302976_0 COG2015 Alkyl sulfatase and related hydrolases K01138 - - 0.0 1031.0
TH3_k127_2302976_1 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 538.0
TH3_k127_2302976_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 332.0
TH3_k127_2302976_3 PFAM transposase, IS4 family protein - - - 0.000000000000001517 79.0
TH3_k127_230759_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 3.176e-226 713.0
TH3_k127_230759_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 6.151e-196 617.0
TH3_k127_230759_2 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 331.0
TH3_k127_230759_3 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 323.0
TH3_k127_230759_4 - - - - 0.000000005398 60.0
TH3_k127_230759_5 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000008284 57.0
TH3_k127_23628_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 416.0
TH3_k127_23628_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 308.0
TH3_k127_23628_2 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000001396 221.0
TH3_k127_23628_3 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.0000000000000000000000003417 107.0
TH3_k127_238828_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000716 295.0
TH3_k127_238828_1 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001333 283.0
TH3_k127_238828_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
TH3_k127_238828_3 Transcriptional regulator, MerR family - - - 0.0000000000000000000000000000000002847 137.0
TH3_k127_238828_4 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000009643 120.0
TH3_k127_238828_5 - - - - 0.0000000000000000000000000007012 121.0
TH3_k127_238828_6 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000007976 116.0
TH3_k127_238828_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000537 93.0
TH3_k127_238828_8 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.00000000126 71.0
TH3_k127_238828_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00002802 55.0
TH3_k127_2412703_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 456.0
TH3_k127_2412703_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 383.0
TH3_k127_2412703_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009656 272.0
TH3_k127_2412703_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006288 244.0
TH3_k127_2412703_4 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000004459 186.0
TH3_k127_2412703_6 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.000008012 50.0
TH3_k127_2428899_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 437.0
TH3_k127_2428899_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000001247 114.0
TH3_k127_2428899_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000007338 75.0
TH3_k127_2428899_3 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00003017 46.0
TH3_k127_2430909_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 532.0
TH3_k127_2430909_1 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 338.0
TH3_k127_2430909_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000004041 198.0
TH3_k127_2430909_3 Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000008267 165.0
TH3_k127_2430909_4 YbbR-like protein - - - 0.00000000000001506 81.0
TH3_k127_2450988_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 381.0
TH3_k127_2450988_1 Belongs to the pseudouridine synthase RluA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002188 258.0
TH3_k127_2450988_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000001025 213.0
TH3_k127_2450988_3 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000002768 167.0
TH3_k127_2450988_4 Protein of unknown function (DUF2283) - - - 0.000000000000000000000000984 105.0
TH3_k127_2450988_5 peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000001196 81.0
TH3_k127_245796_0 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 314.0
TH3_k127_245796_1 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 282.0
TH3_k127_245796_2 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000004642 119.0
TH3_k127_245796_3 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000009088 114.0
TH3_k127_245796_4 Protein of unknown function (DUF1810) - - - 0.0000000004921 60.0
TH3_k127_2464453_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 597.0
TH3_k127_2464453_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 417.0
TH3_k127_2464453_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 398.0
TH3_k127_2464453_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 314.0
TH3_k127_2464453_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000001234 91.0
TH3_k127_24757_0 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.000000000000000000000000000000000000000000000000000000000004796 218.0
TH3_k127_24757_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000002616 189.0
TH3_k127_24757_2 RNase_H superfamily K07502 - - 0.000000005053 57.0
TH3_k127_2482777_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 508.0
TH3_k127_2482777_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 374.0
TH3_k127_2482777_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 340.0
TH3_k127_2482777_3 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 291.0
TH3_k127_2482777_4 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000006748 140.0
TH3_k127_2482813_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 9.973e-199 628.0
TH3_k127_2482813_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 512.0
TH3_k127_2482813_10 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000001216 237.0
TH3_k127_2482813_11 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.00000000000000000000000000000000000000000000001389 175.0
TH3_k127_2482813_12 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000005485 143.0
TH3_k127_2482813_13 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000000000000000000000001898 132.0
TH3_k127_2482813_14 SMART Cold shock protein K03704 - - 0.00000000000000000000000001563 109.0
TH3_k127_2482813_15 peptidase M24 - - - 0.00000000000000000002539 93.0
TH3_k127_2482813_16 - - - - 0.00000001439 64.0
TH3_k127_2482813_2 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 432.0
TH3_k127_2482813_3 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 408.0
TH3_k127_2482813_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 369.0
TH3_k127_2482813_5 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 362.0
TH3_k127_2482813_6 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 340.0
TH3_k127_2482813_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 324.0
TH3_k127_2482813_8 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 292.0
TH3_k127_2482813_9 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005214 283.0
TH3_k127_2490476_0 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 510.0
TH3_k127_2490476_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 430.0
TH3_k127_2490476_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009678 334.0
TH3_k127_2490476_3 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000005008 243.0
TH3_k127_2518269_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 488.0
TH3_k127_2518269_1 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003925 259.0
TH3_k127_2518269_2 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000004867 170.0
TH3_k127_2518269_3 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000006388 145.0
TH3_k127_2518269_4 Tetratricopeptide repeat-like domain - - - 0.0000000000000002544 87.0
TH3_k127_2518269_5 PilZ domain - - - 0.000008192 54.0
TH3_k127_2533454_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 372.0
TH3_k127_2533454_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 335.0
TH3_k127_2533454_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000004871 200.0
TH3_k127_2533454_3 - - - - 0.0000000000000000000000000000000000000000000000000000005462 198.0
TH3_k127_2533454_4 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000001173 129.0
TH3_k127_2533454_5 - - - - 0.0000000000000000000000003685 106.0
TH3_k127_2533454_6 Cytochrome c K08906,K12263 - - 0.000000000000000000001735 98.0
TH3_k127_2533454_7 cytochrome c peroxidase - - - 0.0000000000000000002056 93.0
TH3_k127_2533454_8 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000601 43.0
TH3_k127_2537803_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000191 281.0
TH3_k127_2537803_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001676 275.0
TH3_k127_2537803_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000002038 245.0
TH3_k127_2537803_3 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000001027 237.0
TH3_k127_2537803_4 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000007162 179.0
TH3_k127_2563275_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.822e-311 968.0
TH3_k127_256525_0 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 365.0
TH3_k127_256525_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000001078 231.0
TH3_k127_256525_2 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000006118 228.0
TH3_k127_256525_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000006706 168.0
TH3_k127_256525_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000004045 108.0
TH3_k127_256525_5 PFAM RmuC family K09760 - - 0.0000000000000000003429 92.0
TH3_k127_2573021_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 2.633e-284 897.0
TH3_k127_2573021_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 462.0
TH3_k127_2573021_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 322.0
TH3_k127_2573021_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001094 287.0
TH3_k127_2573021_4 Bacterial protein of unknown function (DUF853) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002987 257.0
TH3_k127_2573021_5 - - - - 0.000000000000000000000000006118 112.0
TH3_k127_2573021_6 protein conserved in bacteria - - - 0.00000000000000000000006806 102.0
TH3_k127_2573021_7 - - - - 0.00000000000000003384 85.0
TH3_k127_2573021_8 Fe-S-cluster oxidoreductase K06940 - - 0.00000004477 57.0
TH3_k127_2580564_0 RmlD substrate binding domain K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 383.0
TH3_k127_2580564_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 387.0
TH3_k127_2580564_10 transferase activity, transferring glycosyl groups - - - 0.0000000000000000007149 100.0
TH3_k127_2580564_11 Glycosyltransferase like family 2 - - - 0.000001349 57.0
TH3_k127_2580564_2 asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 356.0
TH3_k127_2580564_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 308.0
TH3_k127_2580564_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 301.0
TH3_k127_2580564_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002511 249.0
TH3_k127_2580564_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000138 174.0
TH3_k127_2580564_7 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000009391 168.0
TH3_k127_2580564_8 Iron-sulfur cluster-binding domain - - - 0.0000000000000000002515 101.0
TH3_k127_2580564_9 peptidyl-tyrosine sulfation - - - 0.000000000000000000259 92.0
TH3_k127_2586690_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 533.0
TH3_k127_2586690_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000001103 196.0
TH3_k127_2586690_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000003344 162.0
TH3_k127_2633648_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.838e-208 656.0
TH3_k127_2633648_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 316.0
TH3_k127_2633648_10 Ribosomal protein L36 K02919 - - 0.0000000000002367 70.0
TH3_k127_2633648_11 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000007276 64.0
TH3_k127_2633648_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000006832 227.0
TH3_k127_2633648_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000001285 213.0
TH3_k127_2633648_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000007829 205.0
TH3_k127_2633648_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002123 201.0
TH3_k127_2633648_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000572 186.0
TH3_k127_2633648_7 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000003999 182.0
TH3_k127_2633648_8 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000002479 150.0
TH3_k127_2633648_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000008783 130.0
TH3_k127_2647414_0 Proton-conducting membrane transporter - - - 1.328e-195 623.0
TH3_k127_2647414_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 617.0
TH3_k127_2647414_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 473.0
TH3_k127_2647414_3 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 461.0
TH3_k127_2647414_4 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009391 401.0
TH3_k127_2647414_5 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 358.0
TH3_k127_2647414_6 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 334.0
TH3_k127_2647414_7 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000001759 243.0
TH3_k127_2647414_8 PFAM NADH Ubiquinone - - - 0.000000000000000000000000000000000000000000000000000000000000122 221.0
TH3_k127_2647414_9 COGs COG4446 conserved - - - 0.000000000000000000000000000000000000002906 151.0
TH3_k127_2655831_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 504.0
TH3_k127_2655831_1 response regulator K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 332.0
TH3_k127_2655831_2 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.0000000000357 66.0
TH3_k127_2655831_3 Evidence 5 No homology to any previously reported sequences - - - 0.000003766 56.0
TH3_k127_2673376_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 489.0
TH3_k127_2673376_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 491.0
TH3_k127_2676137_0 SMART Elongator protein 3 MiaB NifB - - - 1.561e-212 669.0
TH3_k127_2676137_1 Sulphur transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 379.0
TH3_k127_2676137_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 361.0
TH3_k127_2676137_3 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007682 290.0
TH3_k127_2676137_4 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000003699 260.0
TH3_k127_2676137_5 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001323 227.0
TH3_k127_2676137_6 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000000000007297 130.0
TH3_k127_2676137_7 sulfur carrier activity - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0033554,GO:0042592,GO:0048878,GO:0050896,GO:0051716,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000003196 106.0
TH3_k127_2676137_8 Transposase zinc-ribbon domain - - - 0.0000000000007462 70.0
TH3_k127_2676137_9 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000005619 61.0
TH3_k127_268375_0 catalase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1249.0
TH3_k127_268375_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 402.0
TH3_k127_268375_10 Catalase K03781 - 1.11.1.6 0.00000000001457 64.0
TH3_k127_268375_11 redox protein regulator of disulfide bond formation - - - 0.00000000002269 66.0
TH3_k127_268375_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000001832 56.0
TH3_k127_268375_13 VanZ like family - - - 0.000001355 54.0
TH3_k127_268375_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 353.0
TH3_k127_268375_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000002182 236.0
TH3_k127_268375_4 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000267 222.0
TH3_k127_268375_5 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000001136 202.0
TH3_k127_268375_6 Ferric uptake regulator family K09825 - - 0.000000000000000000000000000000000000003983 150.0
TH3_k127_268375_7 Domain of unknown function (DUF1858) - - - 0.000000000000000001362 88.0
TH3_k127_268375_8 - - - - 0.00000000000000009628 85.0
TH3_k127_2685405_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 619.0
TH3_k127_2685405_1 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000004501 241.0
TH3_k127_2685405_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000001033 178.0
TH3_k127_2685405_3 NosL - - - 0.0000000000000000000000000000000000000000002608 169.0
TH3_k127_2685405_4 NosL - - - 0.000000000000000000000000000000000000000001685 167.0
TH3_k127_2688374_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 479.0
TH3_k127_2688374_1 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 304.0
TH3_k127_2715788_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 3.196e-236 748.0
TH3_k127_2715788_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 617.0
TH3_k127_2715788_2 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000003613 142.0
TH3_k127_2715788_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000007474 66.0
TH3_k127_2715788_4 beta-lactamase activity K07126 - - 0.0002938 48.0
TH3_k127_2718369_0 BadF BadG BcrA BcrD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 411.0
TH3_k127_2718369_1 Major facilitator - - - 0.00000000000000009004 81.0
TH3_k127_2728250_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 452.0
TH3_k127_2728250_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000007847 220.0
TH3_k127_2728250_2 Protein of unknown function (DUF5131) - - - 0.000000000000000000000004801 110.0
TH3_k127_2728250_3 Protein of unknown function (DUF1778) - - - 0.000000000000000007751 87.0
TH3_k127_2738080_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 446.0
TH3_k127_2738080_1 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 410.0
TH3_k127_2738080_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009818 371.0
TH3_k127_2738080_3 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000498 282.0
TH3_k127_2738080_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005882 256.0
TH3_k127_2738080_5 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000009745 246.0
TH3_k127_2738080_6 4Fe-4S binding domain K02574 - - 0.00000000000000000000000000000000000000000000000003916 180.0
TH3_k127_2738080_7 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000000000001424 162.0
TH3_k127_2738080_8 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000000186 119.0
TH3_k127_2738080_9 nitrate reductase K02570 - - 0.000000000000000000001221 97.0
TH3_k127_2746013_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 4.117e-201 642.0
TH3_k127_2746013_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 535.0
TH3_k127_2746013_10 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000034 220.0
TH3_k127_2746013_11 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000002419 62.0
TH3_k127_2746013_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 513.0
TH3_k127_2746013_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 450.0
TH3_k127_2746013_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 404.0
TH3_k127_2746013_5 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 378.0
TH3_k127_2746013_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 370.0
TH3_k127_2746013_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 345.0
TH3_k127_2746013_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 331.0
TH3_k127_2746013_9 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000001242 244.0
TH3_k127_2759522_0 - K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 446.0
TH3_k127_2759522_1 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009821 425.0
TH3_k127_2759522_2 HNH nucleases - - - 0.0000000000000000000000000000000000000001382 153.0
TH3_k127_2759522_3 Periplasmic binding protein - - - 0.00000000000001159 78.0
TH3_k127_2759522_4 - - - - 0.000000000001088 70.0
TH3_k127_2759522_5 Transglycosylase SLT domain - - - 0.00000000004823 71.0
TH3_k127_2759522_6 - - - - 0.0007044 46.0
TH3_k127_2764185_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 574.0
TH3_k127_2764185_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001395 285.0
TH3_k127_2764185_2 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003046 276.0
TH3_k127_2764185_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000007935 99.0
TH3_k127_2764185_4 PFAM Metallophosphoesterase K07098 - - 0.00000000000004946 73.0
TH3_k127_2764185_5 - - - - 0.000000000001507 74.0
TH3_k127_2764185_6 Membrane-bound lysozyme-inhibitor of c-type lysozyme K08985 - - 0.0000000001848 63.0
TH3_k127_287478_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 7.739e-260 812.0
TH3_k127_287478_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 337.0
TH3_k127_287478_2 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 309.0
TH3_k127_287478_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003811 241.0
TH3_k127_287478_4 hydrogenase maturation protease - - - 0.000000000000000000000000000000000004313 143.0
TH3_k127_2879619_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 493.0
TH3_k127_2879619_1 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 423.0
TH3_k127_2879619_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000004466 210.0
TH3_k127_2879619_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000001763 159.0
TH3_k127_2880861_0 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 517.0
TH3_k127_2880861_1 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 492.0
TH3_k127_2880861_2 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 490.0
TH3_k127_2880861_3 - - - - 0.00000000000000000000000000000000000000000000000000000004643 210.0
TH3_k127_2880861_4 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000001382 126.0
TH3_k127_2880861_5 Pentapeptide repeats (9 copies) - - - 0.00000001594 59.0
TH3_k127_2880861_6 Addiction module toxin, RelE StbE family - - - 0.000008518 51.0
TH3_k127_2880861_7 DsrE/DsrF-like family K07092 - - 0.0001036 50.0
TH3_k127_2880861_8 protein homooligomerization - - - 0.0001277 49.0
TH3_k127_2894692_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000001846 235.0
TH3_k127_2894692_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000003225 210.0
TH3_k127_2894692_2 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.00000000000000000000002159 109.0
TH3_k127_2920387_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 473.0
TH3_k127_2920387_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 310.0
TH3_k127_2920387_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000002604 198.0
TH3_k127_2921308_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 4.967e-269 834.0
TH3_k127_2921308_1 carboxylase K01965,K01968 - 6.4.1.3,6.4.1.4 4.34e-255 802.0
TH3_k127_2921308_2 RES - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 456.0
TH3_k127_2921308_3 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 339.0
TH3_k127_2921308_4 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000007219 209.0
TH3_k127_2921308_5 PFAM Acetyl-CoA hydrolase transferase K18122 - - 0.0000000000000000000000000000000007236 132.0
TH3_k127_2921308_6 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000000000000001604 125.0
TH3_k127_2921308_7 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000558 112.0
TH3_k127_2944436_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001079 267.0
TH3_k127_2944436_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000004524 132.0
TH3_k127_2944436_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000003309 100.0
TH3_k127_2945066_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 607.0
TH3_k127_2946062_0 PFAM Mannosyl oligosaccharide glucosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 591.0
TH3_k127_2946062_2 Membrane - - - 0.00000004638 62.0
TH3_k127_2947072_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 407.0
TH3_k127_2947072_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 368.0
TH3_k127_3016982_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 331.0
TH3_k127_3016982_1 helix_turn_helix, Lux Regulon K14979 - - 0.00000000000000000000000000000000000000000000000000000000004799 215.0
TH3_k127_3016982_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000008109 117.0
TH3_k127_3016982_3 Histidine kinase - - - 0.00000000000000004423 97.0
TH3_k127_3016982_4 Response regulator of the LytR AlgR family K08083 - - 0.00000000000000162 82.0
TH3_k127_3016982_5 - - - - 0.00000000000000178 78.0
TH3_k127_3042610_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 358.0
TH3_k127_3042610_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 361.0
TH3_k127_3042610_2 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 356.0
TH3_k127_3042610_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000001188 246.0
TH3_k127_3042610_4 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000008412 179.0
TH3_k127_3042610_5 Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000004712 120.0
TH3_k127_3072343_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 452.0
TH3_k127_3072343_1 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000006447 165.0
TH3_k127_3072343_2 Belongs to the Fur family K09825 - - 0.00000000000000002437 82.0
TH3_k127_3076309_0 cytochrome c peroxidase - - - 0.00000000000000000000000000000000000003397 146.0
TH3_k127_3076309_1 heat shock protein binding - - - 0.000000000000000000000000000000000000724 150.0
TH3_k127_3083500_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 481.0
TH3_k127_3083500_1 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 438.0
TH3_k127_3083500_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000009575 116.0
TH3_k127_3083500_3 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000006721 105.0
TH3_k127_3083500_4 - - - - 0.000000000000000000002595 95.0
TH3_k127_3083500_5 - - - - 0.00000000000000003471 82.0
TH3_k127_3083500_6 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000001494 75.0
TH3_k127_3159611_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 321.0
TH3_k127_3159611_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001099 276.0
TH3_k127_3159611_2 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000001707 199.0
TH3_k127_345845_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1228.0
TH3_k127_345888_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.057e-202 653.0
TH3_k127_345888_1 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000002337 189.0
TH3_k127_345888_2 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000297 159.0
TH3_k127_345888_3 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000006098 124.0
TH3_k127_345888_4 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000001964 125.0
TH3_k127_345888_5 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000679 108.0
TH3_k127_3521178_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 546.0
TH3_k127_3521178_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 360.0
TH3_k127_3521178_10 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000054 133.0
TH3_k127_3521178_11 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000009727 132.0
TH3_k127_3521178_12 PFAM CheW domain protein K03408 - - 0.00000000000000000826 92.0
TH3_k127_3521178_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 302.0
TH3_k127_3521178_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 299.0
TH3_k127_3521178_4 Pfam:Arch_ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001796 285.0
TH3_k127_3521178_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002907 309.0
TH3_k127_3521178_6 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001354 296.0
TH3_k127_3521178_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000002984 248.0
TH3_k127_3521178_8 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000000006475 166.0
TH3_k127_3521178_9 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000004873 149.0
TH3_k127_3528079_0 Protein of unknown function (DUF1254) - - - 1.01e-230 724.0
TH3_k127_3528079_1 Domain of unknown function (DUF4410) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003778 240.0
TH3_k127_3528079_2 Sulfatase K01130 - 3.1.6.1 0.00000000000007844 74.0
TH3_k127_3528079_3 PFAM Citrate transporter - - - 0.0000000002353 61.0
TH3_k127_356697_0 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000001799 234.0
TH3_k127_356697_1 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000002781 149.0
TH3_k127_356697_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000001184 112.0
TH3_k127_356697_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000006174 104.0
TH3_k127_356697_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000002049 92.0
TH3_k127_356697_5 glycerol acyltransferase K07003 - - 0.000063 54.0
TH3_k127_358509_0 DEAD-like helicases superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004162 281.0
TH3_k127_358509_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016614,GO:0030151,GO:0033719,GO:0043167,GO:0043169,GO:0043546,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0097159,GO:1901363 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004648 253.0
TH3_k127_358509_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003466 250.0
TH3_k127_358509_3 - - - - 0.00000000000000001548 85.0
TH3_k127_358509_4 Type III secretion system lipoprotein chaperone (YscW) - - - 0.0003987 44.0
TH3_k127_370509_0 protocatechuate 3,4-dioxygenase - - - 0.0000000000000000000000000000000000000004239 151.0
TH3_k127_370509_1 SMART Cold shock protein K03704 - - 0.00000000000000000000000004045 108.0
TH3_k127_370509_2 RNase H - - - 0.000000000000000001 93.0
TH3_k127_3722324_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000006323 155.0
TH3_k127_3722324_1 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000001012 119.0
TH3_k127_3722324_2 PFAM FG-GAP repeat protein - - - 0.000000000000000000000005195 118.0
TH3_k127_3722324_3 manually curated - - - 0.000001078 52.0
TH3_k127_3736690_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 534.0
TH3_k127_3736690_1 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000001207 239.0
TH3_k127_3736690_2 PHP-associated K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000001998 223.0
TH3_k127_3736690_3 SMART ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000005575 184.0
TH3_k127_3736690_4 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000005832 184.0
TH3_k127_3736690_5 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000005483 147.0
TH3_k127_3736690_6 DRTGG domain - - - 0.0000000000000000000000000000007996 124.0
TH3_k127_3736690_7 DRTGG domain - - - 0.000000000000000000000000002173 118.0
TH3_k127_3736690_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000003437 88.0
TH3_k127_3753013_0 Galactosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 552.0
TH3_k127_3753013_1 - - - - 0.00000000000000000000000000000000000000000000003053 183.0
TH3_k127_3753013_2 Glycosyl hydrolase catalytic core - - - 0.000000000000000000000000000000000000000000001921 175.0
TH3_k127_3753013_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000008141 158.0
TH3_k127_3759441_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 490.0
TH3_k127_3759441_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000006671 86.0
TH3_k127_37824_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 405.0
TH3_k127_37824_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 340.0
TH3_k127_37824_2 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000003487 141.0
TH3_k127_3796567_0 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002348 268.0
TH3_k127_3796567_1 Efflux ABC transporter, permease protein K02004 - - 0.00000000000000000000000000000000000000000000003507 184.0
TH3_k127_3796567_2 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000000000000000000000000000007789 186.0
TH3_k127_3796567_3 cytochrome c biogenesis protein K07399 - - 0.00005942 55.0
TH3_k127_3821757_0 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 552.0
TH3_k127_3821757_1 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000433 245.0
TH3_k127_3821757_2 Protein conserved in bacteria - - - 0.0000000000000000000000000003684 115.0
TH3_k127_3821757_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.000000000000000000000000002139 113.0
TH3_k127_3834975_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 2.783e-274 865.0
TH3_k127_3834975_1 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 494.0
TH3_k127_3834975_2 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 354.0
TH3_k127_3834975_3 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000001672 139.0
TH3_k127_3834975_4 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000001533 79.0
TH3_k127_3834975_5 - - - - 0.000004811 54.0
TH3_k127_3835033_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 5.802e-275 867.0
TH3_k127_3835033_1 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 484.0
TH3_k127_3835033_2 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 339.0
TH3_k127_3835033_3 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000001218 140.0
TH3_k127_385877_0 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000289 238.0
TH3_k127_385877_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000004564 165.0
TH3_k127_385877_2 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000009775 164.0
TH3_k127_385877_3 membrane K07058 - - 0.00000000002129 67.0
TH3_k127_3864034_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.358e-251 782.0
TH3_k127_3864034_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.557e-244 762.0
TH3_k127_3864034_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 331.0
TH3_k127_3864034_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000001165 135.0
TH3_k127_3864034_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000009539 119.0
TH3_k127_3874960_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1202.0
TH3_k127_3874960_1 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 404.0
TH3_k127_3874960_2 SpoIIAA-like - - - 0.0000000000000000003429 92.0
TH3_k127_3874960_3 Integral membrane protein TerC family - - - 0.000000000000001298 80.0
TH3_k127_3874960_4 Universal stress protein family - - - 0.000000001036 63.0
TH3_k127_3884764_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.194e-240 749.0
TH3_k127_3884764_1 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 4.438e-196 619.0
TH3_k127_3884764_2 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001141 276.0
TH3_k127_3884764_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000003789 246.0
TH3_k127_3884764_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000001043 217.0
TH3_k127_3884764_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex - - - 0.0000000000002467 70.0
TH3_k127_3916674_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 327.0
TH3_k127_3916674_1 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000003642 218.0
TH3_k127_3916674_2 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000001415 168.0
TH3_k127_3916674_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000004115 85.0
TH3_k127_3925005_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.672e-236 743.0
TH3_k127_3925005_1 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 567.0
TH3_k127_3925005_10 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000000008621 216.0
TH3_k127_3925005_11 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000001754 213.0
TH3_k127_3925005_12 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000002099 210.0
TH3_k127_3925005_13 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000006765 218.0
TH3_k127_3925005_14 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000005879 164.0
TH3_k127_3925005_15 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000001982 137.0
TH3_k127_3925005_16 YGGT family K02221 - - 0.00000000000000000000000000000003698 128.0
TH3_k127_3925005_17 Transposase - - - 0.000000000000000000000000000002796 121.0
TH3_k127_3925005_18 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.000000000000000000000000004346 115.0
TH3_k127_3925005_19 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.000000000000000000002526 96.0
TH3_k127_3925005_2 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 512.0
TH3_k127_3925005_20 Elements of external origin K07494 - - 0.000000000000000000003204 97.0
TH3_k127_3925005_22 DDE superfamily endonuclease - - - 0.00001035 48.0
TH3_k127_3925005_23 His Kinase A (phosphoacceptor) domain K07651 - 2.7.13.3 0.00002038 50.0
TH3_k127_3925005_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 458.0
TH3_k127_3925005_4 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 446.0
TH3_k127_3925005_5 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 286.0
TH3_k127_3925005_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003712 289.0
TH3_k127_3925005_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008489 274.0
TH3_k127_3925005_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001275 245.0
TH3_k127_3925005_9 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000005036 225.0
TH3_k127_3932908_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 548.0
TH3_k127_3932908_1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000003554 168.0
TH3_k127_3932908_2 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.000000000000000000000000000000000002713 144.0
TH3_k127_3994389_0 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 392.0
TH3_k127_3994389_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 304.0
TH3_k127_3994389_2 flavoproteins K07007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 295.0
TH3_k127_3994389_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001219 288.0
TH3_k127_3994389_4 Preprotein translocase SecG subunit K03075 - - 0.00000000000000001185 87.0
TH3_k127_3994389_5 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.0000000000002777 70.0
TH3_k127_4064603_0 Cytochrome C and Quinol oxidase polypeptide I K04561 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 411.0
TH3_k127_4064603_1 PFAM Cytochrome b5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 289.0
TH3_k127_4064603_2 PFAM HPP family K07168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006281 268.0
TH3_k127_4064603_3 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009729 279.0
TH3_k127_4064603_4 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002167 261.0
TH3_k127_4064603_5 Protein of unknown function (DUF1460) - - - 0.00000000000000000000000000000000000000000000000000000000000000000333 233.0
TH3_k127_4064603_6 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000002816 203.0
TH3_k127_4064603_7 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000005508 156.0
TH3_k127_4064603_8 4Fe-4S binding domain - - - 0.0000000000000000000000000000000002672 143.0
TH3_k127_4064603_9 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000006596 87.0
TH3_k127_407431_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000001241 132.0
TH3_k127_4074381_0 cobalamin synthesis protein, P47K - - - 0.000000000000000000000000000000000000000000004383 175.0
TH3_k127_4074381_1 Acyltransferase family - - - 0.0000000000000000000000000000000000001842 154.0
TH3_k127_4074381_2 Dienelactone hydrolase family - - - 0.000000000000000000000000000001245 127.0
TH3_k127_4074381_3 OsmC-like protein - - - 0.00000000000000000208 94.0
TH3_k127_4074381_4 PFAM response regulator receiver - - - 0.0002532 48.0
TH3_k127_4113171_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 402.0
TH3_k127_4113171_1 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003918 273.0
TH3_k127_4113171_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000002493 230.0
TH3_k127_4113171_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000009659 209.0
TH3_k127_4113171_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000006268 149.0
TH3_k127_4113171_5 Thiamine-binding protein - - - 0.00000000000000000000000000000004053 128.0
TH3_k127_4113171_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000001926 100.0
TH3_k127_4113171_7 - - - - 0.0000000000000000005449 93.0
TH3_k127_4113171_8 Transposase IS200 like - - - 0.0000000000000009066 80.0
TH3_k127_4113171_9 Rubrerythrin - - - 0.0000000478 61.0
TH3_k127_4119949_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000531 133.0
TH3_k127_4123640_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 2.063e-195 616.0
TH3_k127_4123640_1 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 402.0
TH3_k127_4123640_2 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001918 217.0
TH3_k127_4123640_3 Glycosyl transferase family 2 K09931 - - 0.0000000000000000000000000000000000000000000000000000000001444 211.0
TH3_k127_4123640_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000003058 192.0
TH3_k127_4123640_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000001959 180.0
TH3_k127_4123640_6 protein conserved in bacteria K09931 - - 0.00000000000000000000000000000000000003087 153.0
TH3_k127_4123640_7 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.000000000001297 77.0
TH3_k127_4123640_8 6-phosphogluconolactonase K01057 - 3.1.1.31 0.00004851 46.0
TH3_k127_4143597_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000008045 251.0
TH3_k127_4143597_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000003747 209.0
TH3_k127_4143597_2 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000001115 168.0
TH3_k127_4143597_3 Cytochrome P460 - - - 0.000000000000000000000000000000000000001655 153.0
TH3_k127_4143597_4 transferase activity, transferring glycosyl groups - - - 0.00000007933 60.0
TH3_k127_4186823_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 565.0
TH3_k127_4186823_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 468.0
TH3_k127_4186823_10 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000002028 176.0
TH3_k127_4186823_11 - - - - 0.00000000000000215 83.0
TH3_k127_4186823_14 Belongs to the 'phage' integrase family - - - 0.0004827 43.0
TH3_k127_4186823_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 438.0
TH3_k127_4186823_3 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 357.0
TH3_k127_4186823_4 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 307.0
TH3_k127_4186823_5 HD domain K07023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002648 241.0
TH3_k127_4186823_6 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000004865 216.0
TH3_k127_4186823_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000167 187.0
TH3_k127_4186823_8 MGS-like domain - - - 0.00000000000000000000000000000000000000000000007006 178.0
TH3_k127_4186823_9 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000007834 161.0
TH3_k127_4202140_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.912e-246 772.0
TH3_k127_4202140_1 Telomere recombination K04656 - - 3.847e-231 739.0
TH3_k127_4202140_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000549 230.0
TH3_k127_4202140_11 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000003821 192.0
TH3_k127_4202140_12 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000006516 188.0
TH3_k127_4202140_13 radical SAM domain protein - - - 0.000000000000000000000000000000000000002065 162.0
TH3_k127_4202140_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000008629 138.0
TH3_k127_4202140_15 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000000000000000000001898 132.0
TH3_k127_4202140_16 Transposase - - - 0.00000000000000000000000000000252 121.0
TH3_k127_4202140_17 nickel cation binding K04651,K19640 - - 0.0000000000000000000000000001352 119.0
TH3_k127_4202140_18 Hydrolase, P-loop family K06925 - - 0.0000000000000000000000000008425 119.0
TH3_k127_4202140_19 Smr domain - - - 0.000000000000000000000000001827 121.0
TH3_k127_4202140_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 481.0
TH3_k127_4202140_20 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000002848 111.0
TH3_k127_4202140_21 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000001056 108.0
TH3_k127_4202140_22 iron-sulfur cluster assembly - - - 0.000000000000000000000716 96.0
TH3_k127_4202140_23 Tetratricopeptide repeat - - - 0.0000000000008363 78.0
TH3_k127_4202140_24 - - - - 0.000000000004664 72.0
TH3_k127_4202140_26 - - - - 0.00007049 53.0
TH3_k127_4202140_27 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.0001232 53.0
TH3_k127_4202140_3 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 450.0
TH3_k127_4202140_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 402.0
TH3_k127_4202140_5 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 370.0
TH3_k127_4202140_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 316.0
TH3_k127_4202140_7 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 314.0
TH3_k127_4202140_8 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 301.0
TH3_k127_4202140_9 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000001215 241.0
TH3_k127_4248507_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 1.903e-194 628.0
TH3_k127_4248507_1 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005177 269.0
TH3_k127_4248507_2 PFAM response regulator receiver K02483,K18344 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003756 256.0
TH3_k127_4248507_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001245 252.0
TH3_k127_4248507_4 phosphatidate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000006156 239.0
TH3_k127_4248507_5 RNA-binding protein containing a PIN domain K06962 - - 0.00000000000000000000000000000003424 136.0
TH3_k127_4248507_7 Belongs to the UPF0235 family K09131 - - 0.000000000000003353 79.0
TH3_k127_426811_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 444.0
TH3_k127_426811_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 396.0
TH3_k127_426811_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 334.0
TH3_k127_426811_3 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002674 273.0
TH3_k127_432248_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 528.0
TH3_k127_432248_1 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 404.0
TH3_k127_432248_10 cheY-homologous receiver domain K03413 - - 0.000000000000000000000001354 108.0
TH3_k127_432248_11 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000003362 89.0
TH3_k127_432248_12 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000001139 81.0
TH3_k127_432248_13 Chemotaxis phosphatase CheX K03409 - - 0.00000000005759 69.0
TH3_k127_432248_2 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 396.0
TH3_k127_432248_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 326.0
TH3_k127_432248_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 293.0
TH3_k127_432248_5 CheR methyltransferase, all-alpha domain K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000002595 228.0
TH3_k127_432248_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000004309 206.0
TH3_k127_432248_7 endonuclease III K03575 - - 0.00000000000000000000000000000000001281 145.0
TH3_k127_432248_8 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000001045 135.0
TH3_k127_432248_9 GDP-mannose mannosyl hydrolase activity K03574,K08320 - 3.6.1.55,3.6.1.65 0.000000000000000000000000000002072 126.0
TH3_k127_4325156_0 Nitrate nitrite transporter K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 544.0
TH3_k127_4325156_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000002204 75.0
TH3_k127_4325190_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1100.0
TH3_k127_4325190_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004501 244.0
TH3_k127_4325190_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000001955 229.0
TH3_k127_4325190_3 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008161 221.0
TH3_k127_4325190_4 TIGRFAM molybdenum cofactor synthesis - - - 0.0000000000000000000000000000000000000000000000000000006376 196.0
TH3_k127_4325190_5 Belongs to the UPF0758 family K03630 - - 0.0000000001288 66.0
TH3_k127_435418_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000003562 240.0
TH3_k127_435418_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000001357 241.0
TH3_k127_435418_2 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000003865 225.0
TH3_k127_435418_3 permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000004502 156.0
TH3_k127_438245_0 ABC transporter K06020 - 3.6.3.25 4.284e-309 954.0
TH3_k127_438245_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 2.948e-211 668.0
TH3_k127_438245_2 Putative Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 342.0
TH3_k127_438245_3 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000002116 70.0
TH3_k127_441122_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 509.0
TH3_k127_441122_1 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 401.0
TH3_k127_441122_2 protein conserved in bacteria K19158 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006379,GO:0006401,GO:0006402,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016458,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0017148,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0042710,GO:0043021,GO:0043024,GO:0043170,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044764,GO:0044877,GO:0045947,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0098795,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000007629 143.0
TH3_k127_441122_3 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.000000000000000000000000000006214 120.0
TH3_k127_443202_0 Elongation factor G, domain IV K02355 - - 1.053e-293 915.0
TH3_k127_443202_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 531.0
TH3_k127_443202_10 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000007145 159.0
TH3_k127_443202_12 Membrane - - - 0.000000000000000000000002673 109.0
TH3_k127_443202_13 Protein of unknown function (DUF1189) - - - 0.00000000000004253 82.0
TH3_k127_443202_14 PFAM amidohydrolase - - - 0.0000000000001017 76.0
TH3_k127_443202_15 Glutaredoxin - - - 0.000000001185 64.0
TH3_k127_443202_16 PFAM Rhodanese domain protein - - - 0.000000001607 62.0
TH3_k127_443202_17 Amidohydrolase family - - - 0.000000003201 64.0
TH3_k127_443202_18 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000007992 63.0
TH3_k127_443202_19 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000002377 54.0
TH3_k127_443202_2 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 513.0
TH3_k127_443202_20 PFAM Rhodanese domain protein - - - 0.00001035 48.0
TH3_k127_443202_21 Outer membrane lipoprotein - - - 0.0001463 55.0
TH3_k127_443202_3 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 420.0
TH3_k127_443202_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 368.0
TH3_k127_443202_5 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 368.0
TH3_k127_443202_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 353.0
TH3_k127_443202_7 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001157 255.0
TH3_k127_443202_8 - - - - 0.0000000000000000000000000000000000000000000000000006314 187.0
TH3_k127_443202_9 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.000000000000000000000000000000000000000001708 166.0
TH3_k127_4463817_0 Domain of Unknown Function (DUF748) - - - 5.24e-220 726.0
TH3_k127_4463817_1 Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 345.0
TH3_k127_4463817_2 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009206 233.0
TH3_k127_4463817_4 Predicted metal-binding protein (DUF2284) - - - 0.000002897 49.0
TH3_k127_4493561_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1053.0
TH3_k127_4493561_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.188e-202 641.0
TH3_k127_4493561_2 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 339.0
TH3_k127_4493561_3 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000002607 254.0
TH3_k127_4493561_4 Sulphur transport K07112 - - 0.0000000000000000000000000000000000001656 149.0
TH3_k127_4493561_5 Sulphur transport - - - 0.000000000000000000000000000000001297 134.0
TH3_k127_4493561_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000001558 74.0
TH3_k127_4517043_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1046.0
TH3_k127_4517043_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 9.871e-277 854.0
TH3_k127_4527232_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 441.0
TH3_k127_4527232_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 417.0
TH3_k127_4527232_10 sequence-specific DNA binding - - - 0.000000002629 63.0
TH3_k127_4527232_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008444 357.0
TH3_k127_4527232_3 methyltransferase activity - - - 0.00000000000000000000000000000000000000001407 160.0
TH3_k127_4527232_4 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000000000001395 118.0
TH3_k127_4527232_5 Cold shock K03704 - - 0.0000000000000000000000000003005 114.0
TH3_k127_4527232_6 - - - - 0.0000000000000000000001744 99.0
TH3_k127_4527232_7 Phospholipid methyltransferase - - - 0.00000000000000000004099 98.0
TH3_k127_4527232_8 PFAM Integrase catalytic - - - 0.000000000000003607 81.0
TH3_k127_4527232_9 High confidence in function and specificity - - - 0.0000000000001028 74.0
TH3_k127_4556876_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 453.0
TH3_k127_4556876_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000007025 259.0
TH3_k127_4556876_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000001125 187.0
TH3_k127_4556876_3 Radical SAM domain protein - - - 0.000000000000000000000000004964 116.0
TH3_k127_4556876_4 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.0000000003376 68.0
TH3_k127_4565697_0 phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 434.0
TH3_k127_4565697_1 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000001501 233.0
TH3_k127_4565697_2 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000002506 112.0
TH3_k127_4684986_0 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002415 274.0
TH3_k127_4684986_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000007406 233.0
TH3_k127_4684986_2 - - - - 0.0000000000000000000000000001594 116.0
TH3_k127_4684986_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000003431 104.0
TH3_k127_4684986_4 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00027 53.0
TH3_k127_474001_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 1.089e-298 931.0
TH3_k127_474001_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000005206 175.0
TH3_k127_474001_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000828 90.0
TH3_k127_474001_3 EAL domain protein - - - 0.0000000001926 70.0
TH3_k127_474001_4 Glucose / Sorbosone dehydrogenase - - - 0.0000004144 53.0
TH3_k127_479171_0 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001353 278.0
TH3_k127_479171_1 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001449 202.0
TH3_k127_479171_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000001348 175.0
TH3_k127_4911101_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 371.0
TH3_k127_4911101_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000004075 222.0
TH3_k127_4911101_2 SEC-C motif K09858 - - 0.000000000000000000000000000000000000000000000000000000000005698 211.0
TH3_k127_4911101_3 - - - - 0.0000000000000000000000000000000000000000000000000000005568 203.0
TH3_k127_4911101_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000003998 181.0
TH3_k127_4911101_5 Domain of unknown function (DUF389) - - - 0.00000000000000000002966 94.0
TH3_k127_4911101_6 - - - - 0.0000000000002194 72.0
TH3_k127_4958886_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 369.0
TH3_k127_4958886_1 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000000003432 153.0
TH3_k127_4958886_2 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000000000003522 144.0
TH3_k127_4958886_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000001051 82.0
TH3_k127_4958913_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 362.0
TH3_k127_4958913_1 - - - - 0.0000000000000000000000000000000000000004045 154.0
TH3_k127_4958913_2 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000007174 140.0
TH3_k127_4973701_0 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 544.0
TH3_k127_4973701_1 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000002003 222.0
TH3_k127_4973701_2 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000001347 181.0
TH3_k127_4973701_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000001729 150.0
TH3_k127_4973701_4 Predicted permease K07089 - - 0.00000000000000000000000000000001519 127.0
TH3_k127_4973701_5 cell redox homeostasis - - - 0.00000000000000000000001626 101.0
TH3_k127_4973701_6 PFAM Thioredoxin K03671 - - 0.0000000000000000000002648 101.0
TH3_k127_4973701_7 - - - - 0.000000000000641 69.0
TH3_k127_4986130_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.908e-269 848.0
TH3_k127_4986130_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.398e-224 705.0
TH3_k127_4986130_2 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 488.0
TH3_k127_4986130_3 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 374.0
TH3_k127_4986130_4 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 364.0
TH3_k127_4986130_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000009381 224.0
TH3_k127_4986130_6 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000003867 224.0
TH3_k127_4990394_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 9.325e-260 813.0
TH3_k127_4990394_1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus K00341 - 1.6.5.3 6.138e-243 766.0
TH3_k127_4990394_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001267 199.0
TH3_k127_4990394_11 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.0000000000000000000000000000000000000000000000001984 188.0
TH3_k127_4990394_12 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000004846 151.0
TH3_k127_4990394_13 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000006728 148.0
TH3_k127_4990394_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000001805 144.0
TH3_k127_4990394_15 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000008473 143.0
TH3_k127_4990394_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000002423 149.0
TH3_k127_4990394_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000001968 129.0
TH3_k127_4990394_18 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000007886 128.0
TH3_k127_4990394_19 phosphorelay signal transduction system K02437 - - 0.000000000000000000000000005368 121.0
TH3_k127_4990394_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 616.0
TH3_k127_4990394_20 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000002095 94.0
TH3_k127_4990394_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000004809 71.0
TH3_k127_4990394_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 558.0
TH3_k127_4990394_4 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 524.0
TH3_k127_4990394_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 483.0
TH3_k127_4990394_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 433.0
TH3_k127_4990394_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 412.0
TH3_k127_4990394_8 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 356.0
TH3_k127_4990394_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000005445 204.0
TH3_k127_5005891_0 Carbohydrate phosphorylase K00688,K00691 - 2.4.1.1,2.4.1.8 4.184e-296 930.0
TH3_k127_5005891_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 5.626e-216 677.0
TH3_k127_5005891_10 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.00000000000000000000001246 101.0
TH3_k127_5005891_11 GAF domain - - - 0.000001297 57.0
TH3_k127_5005891_12 Transposase (IS116 IS110 IS902 family) K07486 - - 0.0004566 43.0
TH3_k127_5005891_2 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 577.0
TH3_k127_5005891_3 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
TH3_k127_5005891_4 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 291.0
TH3_k127_5005891_5 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005381 274.0
TH3_k127_5005891_6 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004014 254.0
TH3_k127_5005891_7 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000002115 248.0
TH3_k127_5005891_8 Adenylyl-sulfate kinase K00860 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0055114,GO:0071704,GO:1901564 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000008301 215.0
TH3_k127_5005891_9 PFAM Rhodanese domain protein - - - 0.0000000000000000000000007482 111.0
TH3_k127_5006942_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.442e-199 631.0
TH3_k127_5006942_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 7.57e-199 625.0
TH3_k127_5006942_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 448.0
TH3_k127_5006942_3 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 377.0
TH3_k127_5006942_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007228 291.0
TH3_k127_5006942_5 Helix-turn-helix domain - - - 0.00000000000000009801 90.0
TH3_k127_5006942_6 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.00000000006455 65.0
TH3_k127_5006942_7 Stress-induced-phosphoprotein 1 K09553 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0030234,GO:0030544,GO:0031072,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042030,GO:0042886,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0045184,GO:0046907,GO:0050790,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0072655,GO:0097159,GO:0098772,GO:1901363 - 0.0006718 52.0
TH3_k127_5019191_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 596.0
TH3_k127_5019191_1 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 297.0
TH3_k127_5019191_2 IMP dehydrogenase activity K06041,K11527 - 2.7.13.3,5.3.1.13 0.00000000000000000000000000000000000000005254 156.0
TH3_k127_5019191_3 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000001301 126.0
TH3_k127_5019191_4 - - - - 0.0000000000000000000000000000007243 126.0
TH3_k127_5019191_5 phosphorelay signal transduction system - - - 0.00000000000000000000000000003598 121.0
TH3_k127_5019191_6 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000001443 115.0
TH3_k127_5019191_7 IMP dehydrogenase activity K06041,K11527 - 2.7.13.3,5.3.1.13 0.000000000000000000000001511 109.0
TH3_k127_5019191_8 - - - - 0.000000000000007939 81.0
TH3_k127_5037408_0 PFAM Cytochrome bd ubiquinol oxidase, subunit I K00425 - 1.10.3.14 5.892e-208 655.0
TH3_k127_5037408_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 476.0
TH3_k127_5037408_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000001294 188.0
TH3_k127_5037408_3 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 0.0000000000000000000000000000000000000002306 151.0
TH3_k127_5037408_4 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000476 140.0
TH3_k127_5037408_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000002173 82.0
TH3_k127_5062182_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 580.0
TH3_k127_5062182_1 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 500.0
TH3_k127_5062182_10 TfoX N-terminal domain - - - 0.00000000000000000002618 94.0
TH3_k127_5062182_11 Protein of unknown function (DUF2845) - - - 0.00000000000001898 78.0
TH3_k127_5062182_12 Yhs domain-containing protein - - - 0.000000000002146 70.0
TH3_k127_5062182_13 auxin-activated signaling pathway K07088 - - 0.00001807 54.0
TH3_k127_5062182_2 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 380.0
TH3_k127_5062182_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000009372 198.0
TH3_k127_5062182_4 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000003777 169.0
TH3_k127_5062182_5 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000003846 161.0
TH3_k127_5062182_6 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000000000000000000000000000000001035 144.0
TH3_k127_5062182_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000001651 108.0
TH3_k127_5062182_9 phosphorelay signal transduction system - - - 0.00000000000000000000009675 106.0
TH3_k127_5069435_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 554.0
TH3_k127_5069435_1 phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 428.0
TH3_k127_5069435_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 361.0
TH3_k127_5069435_3 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000001012 237.0
TH3_k127_5069435_4 Domain of unknown function (DUF389) - - - 0.0000000000000000001292 91.0
TH3_k127_5095630_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1508.0
TH3_k127_5095630_1 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000002461 121.0
TH3_k127_5115353_0 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 421.0
TH3_k127_5115353_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 417.0
TH3_k127_5115353_2 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 359.0
TH3_k127_5115353_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 307.0
TH3_k127_5126630_0 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1617.0
TH3_k127_5126630_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 339.0
TH3_k127_5126630_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000003283 219.0
TH3_k127_5126630_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000003412 210.0
TH3_k127_5126630_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000000001625 199.0
TH3_k127_5126630_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000003087 148.0
TH3_k127_5130815_0 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000001118 167.0
TH3_k127_5130815_1 Prokaryotic N-terminal methylation motif K02458 - - 0.000000001403 64.0
TH3_k127_5130815_2 Prokaryotic N-terminal methylation motif - - - 0.00000006712 62.0
TH3_k127_5130815_3 fimbrial assembly K02461 - - 0.0000001487 64.0
TH3_k127_5130815_4 Type II secretion system (T2SS), protein M subtype b - - - 0.00001172 55.0
TH3_k127_5163396_0 Glycosyl hydrolases family 43 - - - 0.000000000000000000000000000000000000000000002957 176.0
TH3_k127_5163396_1 conserved protein (DUF2249) K07322 - - 0.0000000000000000000000001641 108.0
TH3_k127_5163396_2 - - - - 0.00000000000000000000002816 105.0
TH3_k127_5170877_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 482.0
TH3_k127_5170877_1 Pfam Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 383.0
TH3_k127_5170877_10 DGC domain - - - 0.0000000000000000000000000004787 118.0
TH3_k127_5170877_11 Arsenical resistance operon trans-acting repressor ArsD - - - 0.000000000000000000000000003104 114.0
TH3_k127_5170877_12 cell redox homeostasis - - - 0.000000000000000000004157 95.0
TH3_k127_5170877_13 PFAM Arsenical resistance operon trans-acting repressor ArsD - - - 0.00000000005745 66.0
TH3_k127_5170877_14 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000005485 61.0
TH3_k127_5170877_15 Low molecular weight phosphatase family K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.000002807 51.0
TH3_k127_5170877_16 Belongs to the HesB IscA family K15724 - - 0.000009475 49.0
TH3_k127_5170877_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 294.0
TH3_k127_5170877_3 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000002584 194.0
TH3_k127_5170877_4 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000011 192.0
TH3_k127_5170877_5 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000001439 172.0
TH3_k127_5170877_6 DGC domain - - - 0.00000000000000000000000000000000000000000000647 166.0
TH3_k127_5170877_7 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000003057 160.0
TH3_k127_5170877_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000002441 149.0
TH3_k127_5170877_9 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000002562 138.0
TH3_k127_5174207_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 469.0
TH3_k127_5174207_1 Dehydrogenase K02030,K03810 - - 0.00000000000000000000000000000000000000001339 154.0
TH3_k127_5174207_2 Maltose acetyltransferase K00633,K00661 - 2.3.1.18,2.3.1.79 0.0000000000000000000006507 101.0
TH3_k127_5181889_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 447.0
TH3_k127_5181889_1 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000001525 167.0
TH3_k127_5181889_2 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000322 137.0
TH3_k127_5181889_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000002026 133.0
TH3_k127_5181889_4 - - - - 0.00000000000000000001357 96.0
TH3_k127_5181889_6 - - - - 0.000000000005706 67.0
TH3_k127_5193776_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 514.0
TH3_k127_5219036_0 Heat shock 70 kDa protein K04043 - - 4.996e-228 714.0
TH3_k127_5219036_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 417.0
TH3_k127_5219036_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001611 283.0
TH3_k127_5219036_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000006119 172.0
TH3_k127_5219036_4 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000034 169.0
TH3_k127_5219036_5 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000006841 104.0
TH3_k127_5219036_6 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000007407 107.0
TH3_k127_5219036_7 - - - - 0.00000006473 55.0
TH3_k127_5219036_8 - - - - 0.00009202 45.0
TH3_k127_5238833_0 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001575 267.0
TH3_k127_5238833_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000003846 185.0
TH3_k127_5238833_2 TIGRFAM death-on-curing family protein K07341 - - 0.00000000000000000000001405 104.0
TH3_k127_5238833_3 - - - - 0.0000000000001373 74.0
TH3_k127_5238833_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.0000000000009361 74.0
TH3_k127_5238833_6 YMGG-like Gly-zipper - - - 0.0000001982 60.0
TH3_k127_5238924_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1214.0
TH3_k127_5238924_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 383.0
TH3_k127_5238924_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000002759 223.0
TH3_k127_5238924_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00000000000000000000000000000000000000000000000000000002701 202.0
TH3_k127_5238924_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000004065 204.0
TH3_k127_5238924_5 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.00000000000000000000000000000000000000006802 156.0
TH3_k127_5238924_6 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000255 137.0
TH3_k127_5247715_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 6.796e-198 624.0
TH3_k127_5247715_1 phosphoribosylformylglycinamidine synthase K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0007275,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009555,GO:0009570,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0030554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048229,GO:0048856,GO:0055046,GO:0097159,GO:0097367,GO:1901265,GO:1901363 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000007578 246.0
TH3_k127_5247715_2 Zeta toxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001548 243.0
TH3_k127_5247715_3 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000002206 97.0
TH3_k127_5247715_4 Type III restriction enzyme res subunit K01156 - 3.1.21.5 0.0000003161 54.0
TH3_k127_5248981_0 TrkA-N domain K03455,K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 377.0
TH3_k127_5248981_1 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 288.0
TH3_k127_5248981_2 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008381 279.0
TH3_k127_5248981_3 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000008268 258.0
TH3_k127_5248981_4 Pfam:TPM K08988 - - 0.0000000000000000000000000000000000000000000000000000002219 201.0
TH3_k127_5248981_6 anti-sigma regulatory factor K04757 - 2.7.11.1 0.0000000000000006749 81.0
TH3_k127_5248981_7 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000009557 81.0
TH3_k127_5261462_0 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 410.0
TH3_k127_5261462_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 354.0
TH3_k127_5261462_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000007406 100.0
TH3_k127_5261462_11 Phosphopantetheine attachment site - - - 0.000000000000000007528 91.0
TH3_k127_5261462_12 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000008845 77.0
TH3_k127_5261462_13 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000001186 53.0
TH3_k127_5261462_14 PFAM Transposase, IS4-like - - - 0.0000001226 54.0
TH3_k127_5261462_15 transposase activity - - - 0.0001011 44.0
TH3_k127_5261462_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 347.0
TH3_k127_5261462_3 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000003956 248.0
TH3_k127_5261462_4 KR domain - - - 0.0000000000000000000000000000000000000000000004052 177.0
TH3_k127_5261462_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000003089 168.0
TH3_k127_5261462_6 PFAM transposase IS3 IS911 family protein K07497 - - 0.0000000000000000000000000000000000000001079 152.0
TH3_k127_5261462_7 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000005903 158.0
TH3_k127_5261462_8 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.000000000000000000000000000000000000589 156.0
TH3_k127_5261462_9 FabA-like domain K02372 - 4.2.1.59 0.00000000000000000000002722 104.0
TH3_k127_5408240_0 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 1.497e-265 837.0
TH3_k127_5408240_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.861e-197 633.0
TH3_k127_5408240_10 Oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001212 280.0
TH3_k127_5408240_11 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000004478 243.0
TH3_k127_5408240_12 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000000000000000000000000001761 205.0
TH3_k127_5408240_13 AAA domain - - - 0.0000000000000000000000000000000000000000000000000001088 190.0
TH3_k127_5408240_14 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000001204 156.0
TH3_k127_5408240_15 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000002349 140.0
TH3_k127_5408240_16 - - - - 0.00000000000000000000000000461 114.0
TH3_k127_5408240_17 pilus assembly - - - 0.0001686 48.0
TH3_k127_5408240_2 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 607.0
TH3_k127_5408240_3 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 443.0
TH3_k127_5408240_4 PFAM Class II aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 332.0
TH3_k127_5408240_5 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 316.0
TH3_k127_5408240_6 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 315.0
TH3_k127_5408240_7 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 310.0
TH3_k127_5408240_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 289.0
TH3_k127_5408240_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001077 269.0
TH3_k127_5429600_0 PFAM multicopper oxidase type 2 - - - 3.279e-263 834.0
TH3_k127_5429600_1 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000000000000000000000000000000000000006012 167.0
TH3_k127_5483474_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 8.586e-267 842.0
TH3_k127_5483474_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 438.0
TH3_k127_5483474_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 353.0
TH3_k127_5483474_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 335.0
TH3_k127_5483474_4 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 312.0
TH3_k127_5483474_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000001636 225.0
TH3_k127_5483474_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000008013 126.0
TH3_k127_5483474_7 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000003627 86.0
TH3_k127_5483474_8 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00000000005372 66.0
TH3_k127_548426_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 346.0
TH3_k127_548426_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002145 297.0
TH3_k127_548426_2 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001385 278.0
TH3_k127_548426_3 NosL - - - 0.00000000000000000000000000000000000000000000000000000000001395 211.0
TH3_k127_548426_4 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000003665 185.0
TH3_k127_548426_5 Predicted membrane protein (DUF2318) - - - 0.000000000000007633 81.0
TH3_k127_548426_6 integral membrane protein - - - 0.0000005471 61.0
TH3_k127_5487428_0 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 565.0
TH3_k127_5487428_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 559.0
TH3_k127_5487428_10 Universal stress protein family K07090 - - 0.00000000000000000000000000000001075 143.0
TH3_k127_5487428_2 Chromate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 461.0
TH3_k127_5487428_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 429.0
TH3_k127_5487428_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000006471 225.0
TH3_k127_5487428_5 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000001951 224.0
TH3_k127_5487428_6 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.0000000000000000000000000000000000000000000000000000000001685 220.0
TH3_k127_5487428_7 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000002215 142.0
TH3_k127_5487428_8 nucleotide metabolic process - - - 0.00000000000000000000000000000000002082 144.0
TH3_k127_5487428_9 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000001038 132.0
TH3_k127_5493170_0 Phage tail sheath C-terminal domain K06907 - - 1.566e-233 729.0
TH3_k127_5493170_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 381.0
TH3_k127_5493170_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 316.0
TH3_k127_5493170_3 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000000000000000000002825 231.0
TH3_k127_5493170_4 Transcription termination factor nusG - - - 0.0000000000000000000000000000007775 127.0
TH3_k127_5507322_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 593.0
TH3_k127_5507322_1 ABC transporter transmembrane region K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 519.0
TH3_k127_5507322_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000003624 207.0
TH3_k127_5507322_11 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000634 212.0
TH3_k127_5507322_12 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000001284 198.0
TH3_k127_5507322_13 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000006685 148.0
TH3_k127_5507322_14 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000006619 154.0
TH3_k127_5507322_15 Glycosyl transferases group 1 - - - 0.00000000000000000000000001134 124.0
TH3_k127_5507322_16 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.00000000000000004378 93.0
TH3_k127_5507322_17 Transposase DDE domain - - - 0.0000000179 59.0
TH3_k127_5507322_18 O-Antigen ligase - - - 0.00000473 59.0
TH3_k127_5507322_19 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00009597 53.0
TH3_k127_5507322_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 412.0
TH3_k127_5507322_3 transferase activity, transferring glycosyl groups K02844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 325.0
TH3_k127_5507322_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 319.0
TH3_k127_5507322_5 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 311.0
TH3_k127_5507322_6 biosynthesis glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 298.0
TH3_k127_5507322_7 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 291.0
TH3_k127_5507322_8 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000001044 234.0
TH3_k127_5507322_9 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000004434 231.0
TH3_k127_5578827_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.532e-261 832.0
TH3_k127_5578827_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 345.0
TH3_k127_5578827_2 Reverse transcriptase (RNA-dependent DNA polymerase) K00986,K15342 - 2.7.7.49 0.000000000000000000000000000000000000000000001974 171.0
TH3_k127_5616063_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.277e-243 767.0
TH3_k127_5616063_1 GAF domain - - - 1.495e-207 697.0
TH3_k127_5616063_10 PFAM Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000005033 160.0
TH3_k127_5616063_11 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000002005 119.0
TH3_k127_5616063_12 phosphorelay signal transduction system - - - 0.0000000000000000000000000002148 123.0
TH3_k127_5616063_13 Diguanylate cyclase, GGDEF domain - - - 0.0000000000001056 72.0
TH3_k127_5616063_14 diguanylate cyclase K13590 - 2.7.7.65 0.00001369 49.0
TH3_k127_5616063_2 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 436.0
TH3_k127_5616063_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 359.0
TH3_k127_5616063_4 PFAM ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 332.0
TH3_k127_5616063_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 305.0
TH3_k127_5616063_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000171 244.0
TH3_k127_5616063_7 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000146 184.0
TH3_k127_5616063_8 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000008855 165.0
TH3_k127_5616063_9 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000001231 160.0
TH3_k127_5627198_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 414.0
TH3_k127_5627198_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001003 254.0
TH3_k127_5633663_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 495.0
TH3_k127_5633663_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 429.0
TH3_k127_5633663_2 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000000002173 136.0
TH3_k127_5633663_3 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000271 117.0
TH3_k127_5633663_4 Domain of unknown function (DUF296) - - - 0.0000000000000006549 78.0
TH3_k127_5633663_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000001629 81.0
TH3_k127_5645972_0 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 4.56e-199 631.0
TH3_k127_5645972_1 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 425.0
TH3_k127_5645972_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 344.0
TH3_k127_5645972_3 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001286 266.0
TH3_k127_5645972_4 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000005716 181.0
TH3_k127_5645972_5 PFAM MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000000001607 176.0
TH3_k127_5645972_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000002632 93.0
TH3_k127_5645972_8 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.0000000000000003822 87.0
TH3_k127_5747037_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 5.183e-263 827.0
TH3_k127_5747037_1 Highly conserved protein containing a thioredoxin domain K06888,K20948 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 444.0
TH3_k127_5747037_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 422.0
TH3_k127_5747037_3 PFAM glycosyl transferase WecB TagA CpsF K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000001745 256.0
TH3_k127_5799870_0 Putative peptidoglycan binding domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 402.0
TH3_k127_5799870_1 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000001774 191.0
TH3_k127_5799870_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000008557 78.0
TH3_k127_5849004_0 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005248 244.0
TH3_k127_5849004_1 Phospholipid methyltransferase - - - 0.000000000000000009523 91.0
TH3_k127_5849004_2 NHL repeat containing protein - - - 0.000000000000002118 91.0
TH3_k127_5849004_3 Elongation factor SelB, winged helix K03833 - - 0.000000000000008248 75.0
TH3_k127_5849004_4 - - - - 0.000000006149 61.0
TH3_k127_5891928_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 520.0
TH3_k127_5891928_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 434.0
TH3_k127_5891928_2 - - - - 0.00001723 51.0
TH3_k127_6024288_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 470.0
TH3_k127_6024288_1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 364.0
TH3_k127_6092601_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 571.0
TH3_k127_6092601_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 354.0
TH3_k127_6092601_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 320.0
TH3_k127_6092601_3 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000001638 237.0
TH3_k127_6092601_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000001656 173.0
TH3_k127_6092601_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000007599 128.0
TH3_k127_6092601_6 YtkA-like - - - 0.00000000000461 73.0
TH3_k127_6092601_7 PilZ domain - - - 0.0000002198 59.0
TH3_k127_6186121_0 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 482.0
TH3_k127_6186121_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 457.0
TH3_k127_6186121_2 PFAM binding-protein-dependent transport systems inner membrane component K02046,K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 385.0
TH3_k127_6186121_3 Sulfate ABC transporter, permease K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 370.0
TH3_k127_6186121_4 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000003443 263.0
TH3_k127_6186121_5 Transcriptional regulator, BadM Rrf2 family - - - 0.00000000000000000000000000000000000000002079 156.0
TH3_k127_6188265_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1483.0
TH3_k127_6188265_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 7.557e-262 824.0
TH3_k127_6188265_10 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.000000009597 63.0
TH3_k127_6188265_11 Pfam:N_methyl_2 K02459 - - 0.000001243 58.0
TH3_k127_6188265_12 Belongs to the N-Me-Phe pilin family K02650 - - 0.000002145 55.0
TH3_k127_6188265_13 type IV pilus modification protein PilV K02458 - - 0.000006047 57.0
TH3_k127_6188265_14 Type IV pilin PilA - - - 0.00000697 56.0
TH3_k127_6188265_2 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 341.0
TH3_k127_6188265_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 301.0
TH3_k127_6188265_4 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002342 251.0
TH3_k127_6188265_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000514 217.0
TH3_k127_6188265_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000005765 201.0
TH3_k127_6188265_7 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000006826 201.0
TH3_k127_6188265_8 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000001243 188.0
TH3_k127_6188265_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000001824 116.0
TH3_k127_6203412_0 Aminotransferase class I and II K14261 - - 5.313e-210 657.0
TH3_k127_6203412_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 526.0
TH3_k127_6203412_10 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000002985 186.0
TH3_k127_6203412_11 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000002645 139.0
TH3_k127_6203412_12 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000006096 132.0
TH3_k127_6203412_13 JAB/MPN domain K21140 - 3.13.1.6 0.00000000000000000000000004898 111.0
TH3_k127_6203412_14 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000008584 91.0
TH3_k127_6203412_15 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000003214 81.0
TH3_k127_6203412_2 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 367.0
TH3_k127_6203412_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 344.0
TH3_k127_6203412_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 313.0
TH3_k127_6203412_5 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 308.0
TH3_k127_6203412_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 290.0
TH3_k127_6203412_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001208 243.0
TH3_k127_6203412_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000007773 208.0
TH3_k127_6203412_9 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000001156 201.0
TH3_k127_6205604_0 Heat shock 70 kDa protein K04043 - - 3.314e-320 989.0
TH3_k127_6205604_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.474e-283 882.0
TH3_k127_6205604_10 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 399.0
TH3_k127_6205604_11 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 339.0
TH3_k127_6205604_12 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 316.0
TH3_k127_6205604_13 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 310.0
TH3_k127_6205604_14 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 312.0
TH3_k127_6205604_15 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 299.0
TH3_k127_6205604_16 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 287.0
TH3_k127_6205604_17 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003767 268.0
TH3_k127_6205604_18 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002785 265.0
TH3_k127_6205604_19 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000001009 175.0
TH3_k127_6205604_2 Molecular chaperone. Has ATPase activity K04079 - - 4.651e-264 827.0
TH3_k127_6205604_20 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000000000000002469 143.0
TH3_k127_6205604_21 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000002733 149.0
TH3_k127_6205604_22 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000001968 136.0
TH3_k127_6205604_23 Cold-shock DNA-binding domain protein K03704 - - 0.0000000000000000000000001241 107.0
TH3_k127_6205604_24 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000009 114.0
TH3_k127_6205604_25 protein-glutamate methylesterase activity K03412,K03413,K18876 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 3.1.1.61,3.5.1.44 0.00000000000000000000000719 109.0
TH3_k127_6205604_26 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.000000000000000000001587 96.0
TH3_k127_6205604_27 Protein of unknown function (DUF1722) - - - 0.00000000000000002356 83.0
TH3_k127_6205604_28 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000001842 91.0
TH3_k127_6205604_29 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000001347 81.0
TH3_k127_6205604_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.65e-231 732.0
TH3_k127_6205604_31 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000009946 78.0
TH3_k127_6205604_35 - - - - 0.00000008084 56.0
TH3_k127_6205604_37 Polyketide cyclase / dehydrase and lipid transport - - - 0.0002033 46.0
TH3_k127_6205604_38 PBS lyase HEAT-like repeat - - - 0.0002301 52.0
TH3_k127_6205604_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 492.0
TH3_k127_6205604_5 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 487.0
TH3_k127_6205604_6 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 477.0
TH3_k127_6205604_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 473.0
TH3_k127_6205604_8 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 423.0
TH3_k127_6205604_9 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 409.0
TH3_k127_6235545_0 Histidine kinase - - - 6.67e-322 1009.0
TH3_k127_6235545_1 GTP-binding GTPase Middle Region K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 566.0
TH3_k127_6235545_2 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 338.0
TH3_k127_6235545_3 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.0000000000000000000000000000000000000000000000000000000000006808 214.0
TH3_k127_6237599_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 544.0
TH3_k127_6237599_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 366.0
TH3_k127_6237599_2 GYD domain - - - 0.000000000000000000000000000000000296 134.0
TH3_k127_6237599_3 sulfur carrier activity K04085 - - 0.0000000000000000000123 94.0
TH3_k127_6237599_4 to Salmonella typhimurium, and Salmonella typhi transposase for insertion sequence IS200 TnpA SW T200_SALTY (Q57334) (152 aa) fasta scores E() 0, 94.1 id in 152 aa. Identical to the Yersinia pseudotuberculosis IS1541-like element transposase Tnp TR Q9X9F5 (EMBL AJ238014) (152 aa) fasta scores E() 0, 100.0 id in 152 aa K07491 - - 0.00000000421 60.0
TH3_k127_6237599_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000004618 53.0
TH3_k127_6300244_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 345.0
TH3_k127_6300244_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001293 271.0
TH3_k127_6300244_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.00000000000000000000000000000000000000000000000000000001266 203.0
TH3_k127_6300244_3 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000008014 151.0
TH3_k127_6300244_4 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000009202 148.0
TH3_k127_6300244_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000002761 122.0
TH3_k127_6300244_6 energy transducer activity K03646,K03832 - - 0.00000000000000002867 91.0
TH3_k127_6300244_7 DnaJ molecular chaperone homology domain - - - 0.000001371 60.0
TH3_k127_6311006_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.221e-224 707.0
TH3_k127_6311006_1 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 505.0
TH3_k127_6311006_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 471.0
TH3_k127_6311006_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 457.0
TH3_k127_6311006_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 325.0
TH3_k127_6311006_5 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 316.0
TH3_k127_6311006_6 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000001088 117.0
TH3_k127_6311006_7 DDE superfamily endonuclease - - - 0.000001356 51.0
TH3_k127_6349007_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 367.0
TH3_k127_6349007_1 DNA polymerase K02347 - - 0.0000000000000000000000000000004045 124.0
TH3_k127_6349007_2 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000004612 110.0
TH3_k127_6349007_3 electron transfer activity K03439,K05337 - 2.1.1.33 0.0000000000001565 72.0
TH3_k127_6349007_4 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000008016 66.0
TH3_k127_6400777_0 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 551.0
TH3_k127_6400777_1 PFAM Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 531.0
TH3_k127_6400777_10 - - - - 0.00000003556 57.0
TH3_k127_6400777_11 Protein of unknown function (DUF445) - - - 0.0003462 48.0
TH3_k127_6400777_2 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 364.0
TH3_k127_6400777_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 343.0
TH3_k127_6400777_4 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002638 254.0
TH3_k127_6400777_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000043 206.0
TH3_k127_6400777_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000004646 158.0
TH3_k127_6400777_7 Histidine kinase - - - 0.00000000000000000000000000000000000000006085 170.0
TH3_k127_6400777_8 hmm pf01609 - - - 0.00000000000000000000000000000000003142 139.0
TH3_k127_6400777_9 HAMP domain - - - 0.000000000000000000000005966 117.0
TH3_k127_6413862_0 Sugar (and other) transporter K03446 - - 3.418e-231 726.0
TH3_k127_6413862_1 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 383.0
TH3_k127_6413862_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 376.0
TH3_k127_6413862_3 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000002993 219.0
TH3_k127_6413862_4 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000004681 221.0
TH3_k127_6413862_5 ABC1 family K03688 - - 0.0000000000000000000000000000000000002909 145.0
TH3_k127_6413862_6 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000003791 117.0
TH3_k127_6417372_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 412.0
TH3_k127_6417372_1 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 375.0
TH3_k127_6417372_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000001609 139.0
TH3_k127_6417372_3 ResB family K07399 - - 0.0000000000000000000001419 102.0
TH3_k127_6417372_4 - - - - 0.00000001796 60.0
TH3_k127_6441311_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 5.916e-292 911.0
TH3_k127_6441311_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 451.0
TH3_k127_6441311_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 417.0
TH3_k127_6441311_3 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 397.0
TH3_k127_6441311_4 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 379.0
TH3_k127_6441311_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000001808 233.0
TH3_k127_6441311_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000004296 195.0
TH3_k127_6441311_7 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000763 130.0
TH3_k127_6441311_8 DoxX K15977 - - 0.0000000000000000000000127 102.0
TH3_k127_6441311_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000003031 60.0
TH3_k127_6483754_0 lipoprotein localization to outer membrane K02004,K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 466.0
TH3_k127_6483754_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 422.0
TH3_k127_6483754_2 lipoprotein transporter activity K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 298.0
TH3_k127_6483754_3 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.000000000000000000000000000008252 120.0
TH3_k127_6483754_4 - - - - 0.000000000000000000002689 99.0
TH3_k127_6483754_5 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0002378 45.0
TH3_k127_6487158_0 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 479.0
TH3_k127_6487158_1 Protein export membrane protein K03296,K18138 - - 0.00000000000000000000000000000000000000000000000002629 181.0
TH3_k127_6546364_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 488.0
TH3_k127_6546364_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 340.0
TH3_k127_6546364_10 Polysaccharide biosynthesis/export protein K01991 - - 0.0008371 48.0
TH3_k127_6546364_2 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 318.0
TH3_k127_6546364_3 Bacterial type II and III secretion system protein K02453,K03219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007069 302.0
TH3_k127_6546364_4 Transposase K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003278 244.0
TH3_k127_6546364_5 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.00000000000000000000000000000003894 132.0
TH3_k127_6546364_6 protein involved in exopolysaccharide biosynthesis K16554 - - 0.00000000000000000000000283 113.0
TH3_k127_6546364_7 - - - - 0.000000000000000000002437 97.0
TH3_k127_6546364_8 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000008188 100.0
TH3_k127_6546364_9 biosynthesis protein K01104 - 3.1.3.48 0.0000000000003581 74.0
TH3_k127_6547721_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 410.0
TH3_k127_6547721_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 400.0
TH3_k127_6547721_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 336.0
TH3_k127_6547721_3 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007171 271.0
TH3_k127_6547721_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000003624 269.0
TH3_k127_6547721_5 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000009522 185.0
TH3_k127_6547721_6 DUF218 domain - - - 0.0000000000000000000007263 103.0
TH3_k127_6559689_0 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 476.0
TH3_k127_6559689_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 435.0
TH3_k127_6559689_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 402.0
TH3_k127_6559689_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 379.0
TH3_k127_6559689_4 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 357.0
TH3_k127_6559689_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000003745 236.0
TH3_k127_6559689_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000007849 146.0
TH3_k127_6565013_0 PFAM ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002715 259.0
TH3_k127_6565013_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000001097 105.0
TH3_k127_6565013_2 Domain of unknown function (DUF4034) - - - 0.0000000005852 72.0
TH3_k127_6616665_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 566.0
TH3_k127_6616665_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00002443 47.0
TH3_k127_6633293_0 AcrB/AcrD/AcrF family K03296,K07788,K07789,K18138 - - 0.0 1714.0
TH3_k127_6633293_1 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 552.0
TH3_k127_6633293_10 RelB antitoxin K07473 - - 0.0009014 46.0
TH3_k127_6633293_2 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 360.0
TH3_k127_6633293_3 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001827 246.0
TH3_k127_6633293_4 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000000000000000000000000000000000000000000000397 226.0
TH3_k127_6633293_5 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000008005 212.0
TH3_k127_6633293_6 TIGRFAM molybdenum cofactor synthesis domain - - - 0.0000000000000000000000000000000000000000000000000000000003934 206.0
TH3_k127_6633293_7 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000001092 205.0
TH3_k127_6633293_8 response regulator, receiver K02658,K03413 - - 0.0000000000000000000000006916 108.0
TH3_k127_6633293_9 nuclease activity - - - 0.000000000000000000000004797 105.0
TH3_k127_6656499_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002665 284.0
TH3_k127_6656499_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002438 252.0
TH3_k127_6656499_2 Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity) K03466 - - 0.000000000000000002113 96.0
TH3_k127_667416_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 469.0
TH3_k127_667416_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 452.0
TH3_k127_667416_2 PFAM Sulphate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 293.0
TH3_k127_667416_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000003526 117.0
TH3_k127_667416_4 PFAM Carbohydrate-selective porin OprB K07267 - - 0.0000000000000003441 82.0
TH3_k127_667416_5 Cysteine-rich secretory protein family - - - 0.0000000002227 61.0
TH3_k127_667416_6 Regulatory protein, FmdB family - - - 0.000000007235 59.0
TH3_k127_6680188_0 glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002531 271.0
TH3_k127_6680188_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000004658 233.0
TH3_k127_6680188_2 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000006862 177.0
TH3_k127_6680188_3 acetyltransferase - - - 0.00000000000000000000828 102.0
TH3_k127_6680188_4 Type IV pilin PilA K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000000003201 64.0
TH3_k127_6680188_5 Belongs to the N-Me-Phe pilin family K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000000191 59.0
TH3_k127_6680188_6 Prokaryotic N-terminal methylation motif K02650,K02655 - - 0.0000002099 59.0
TH3_k127_6697844_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.718e-196 620.0
TH3_k127_6697844_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 316.0
TH3_k127_6697844_2 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 308.0
TH3_k127_6697844_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000004436 267.0
TH3_k127_6697844_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003659 244.0
TH3_k127_6697844_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000002536 177.0
TH3_k127_6697844_6 energy transducer activity K03832 - - 0.00000000000000000000000000000000000005513 153.0
TH3_k127_6697844_7 Universal stress protein family - - - 0.0000000000000000000000000000000000006803 145.0
TH3_k127_6697844_8 proteolysis K03665 - - 0.000000000000000000000000000005626 126.0
TH3_k127_6697844_9 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000004839 113.0
TH3_k127_6708030_0 Surface antigen K07277 - - 3.392e-248 786.0
TH3_k127_6708030_1 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 604.0
TH3_k127_6708030_10 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000001774 188.0
TH3_k127_6708030_11 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000001312 184.0
TH3_k127_6708030_12 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000001124 164.0
TH3_k127_6708030_13 12 heme-binding sites - - - 0.000000000000000000000000000000000000004273 156.0
TH3_k127_6708030_14 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000005279 151.0
TH3_k127_6708030_15 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000000000000000000871 128.0
TH3_k127_6708030_16 GDP-mannose mannosyl hydrolase activity - - - 0.000000000000000002344 87.0
TH3_k127_6708030_2 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 562.0
TH3_k127_6708030_3 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 547.0
TH3_k127_6708030_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 391.0
TH3_k127_6708030_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 369.0
TH3_k127_6708030_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 319.0
TH3_k127_6708030_7 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
TH3_k127_6708030_8 Psort location Cytoplasmic, score 8.96 K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001411 256.0
TH3_k127_6708030_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000005182 208.0
TH3_k127_6722595_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 2.844e-299 932.0
TH3_k127_6722595_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 578.0
TH3_k127_6722595_10 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000000000000000000000002421 136.0
TH3_k127_6722595_11 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.0000000000000000000000000000000001733 151.0
TH3_k127_6722595_12 Uncharacterized ACR, COG1678 - - - 0.00000000000000000000000000005106 125.0
TH3_k127_6722595_13 COG2202 FOG PAS PAC domain - - - 0.00000000000000000000001112 119.0
TH3_k127_6722595_14 part of a sulfur-relay system K11179 - - 0.00000000000000000000004537 104.0
TH3_k127_6722595_15 Domain of unknown function (DUF305) - - - 0.000000000000002489 79.0
TH3_k127_6722595_2 Chalcone and stilbene synthases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 428.0
TH3_k127_6722595_3 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 321.0
TH3_k127_6722595_4 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003623 247.0
TH3_k127_6722595_5 transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006552 253.0
TH3_k127_6722595_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000003294 235.0
TH3_k127_6722595_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000002814 225.0
TH3_k127_6722595_8 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000001495 194.0
TH3_k127_6722595_9 40-residue yvtn family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000004263 152.0
TH3_k127_6754428_0 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 542.0
TH3_k127_6754428_1 Protein of unknown function DUF262 - - - 0.00000000000000000000000000000000000000000002196 175.0
TH3_k127_6754428_2 CobB/CobQ-like glutamine amidotransferase domain K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000002939 122.0
TH3_k127_6754428_3 Protein of unknown function (DUF2892) - - - 0.00000000000000000001667 92.0
TH3_k127_6754428_6 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000001283 53.0
TH3_k127_6762821_0 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 439.0
TH3_k127_6762821_1 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 295.0
TH3_k127_6762821_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000001773 192.0
TH3_k127_6762821_3 PFAM Transposase DDE domain - - - 0.00000000000002637 75.0
TH3_k127_6764265_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 499.0
TH3_k127_6764265_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003644 270.0
TH3_k127_6764265_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000003827 179.0
TH3_k127_6764265_3 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000003171 138.0
TH3_k127_6764265_4 PFAM PQQ enzyme repeat - - - 0.000000000000000000000007053 110.0
TH3_k127_6777631_0 ATPase involved in DNA repair - - - 5.763e-253 810.0
TH3_k127_6777631_1 cysteine protease - - - 4.306e-244 769.0
TH3_k127_6777631_10 protein of Photorhabdus and some similarities with - - - 0.000000000001749 80.0
TH3_k127_6777631_11 tail collar domain protein K01406,K21449 - 3.4.24.40 0.00000000002154 70.0
TH3_k127_6777631_12 Belongs to the 'phage' integrase family - - - 0.0000000001367 70.0
TH3_k127_6777631_13 Putative peptidoglycan binding domain - - - 0.0005698 51.0
TH3_k127_6777631_2 PFAM ATPase family associated with various cellular activities (AAA) - - - 1.062e-221 695.0
TH3_k127_6777631_3 Protein of unknown function (DUF499) K06922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 559.0
TH3_k127_6777631_4 PFAM peptidase C14, caspase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 396.0
TH3_k127_6777631_5 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 359.0
TH3_k127_6777631_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11354 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 259.0
TH3_k127_6777631_7 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000002803 166.0
TH3_k127_6777631_8 - - - - 0.00000000000000000000000000000000001109 143.0
TH3_k127_6777631_9 Domain of unknown function (DUF4157) - - - 0.00000000000001262 89.0
TH3_k127_6799898_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 376.0
TH3_k127_6799898_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000008315 222.0
TH3_k127_6799898_2 2 iron, 2 sulfur cluster binding K01465,K02823,K05784,K17828 - 1.3.1.14,3.5.2.3 0.000000000000000000000000000000000000000000000000002952 190.0
TH3_k127_6853324_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 423.0
TH3_k127_6853324_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003036 292.0
TH3_k127_6853324_2 Transposase IS200 like - - - 0.00000000000000000001935 93.0
TH3_k127_6853324_3 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000002158 79.0
TH3_k127_6853324_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00003242 49.0
TH3_k127_6866923_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000001055 92.0
TH3_k127_6866923_1 Helicase conserved C-terminal domain - - - 0.000000002674 60.0
TH3_k127_6866923_2 response regulator - - - 0.00003331 46.0
TH3_k127_6880462_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009919 555.0
TH3_k127_6880462_2 PFAM VanZ - - - 0.00000000001048 72.0
TH3_k127_699980_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 478.0
TH3_k127_699980_1 cytochrome c biogenesis protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 352.0
TH3_k127_699980_2 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 342.0
TH3_k127_699980_3 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 345.0
TH3_k127_699980_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001024 211.0
TH3_k127_699980_6 ABC transporter, permease protein K02004 - - 0.000000000000000000000000000000000000000000000000000102 194.0
TH3_k127_699980_7 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000000000000003728 147.0
TH3_k127_699980_8 Pentapeptide repeats (8 copies) - - - 0.000000000000008445 81.0
TH3_k127_699980_9 Glycosyl transferase family 2 - - - 0.0001944 45.0
TH3_k127_7019471_0 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 520.0
TH3_k127_7082135_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 422.0
TH3_k127_7126411_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.457e-252 785.0
TH3_k127_7126411_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.27e-240 751.0
TH3_k127_7126411_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 333.0
TH3_k127_7126411_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000261 155.0
TH3_k127_7126411_4 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000003004 156.0
TH3_k127_7126411_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000001119 140.0
TH3_k127_7166032_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 538.0
TH3_k127_7166032_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 521.0
TH3_k127_7166032_10 cyclic nucleotide binding K01420,K10716,K10914 - - 0.000000000000000000000000000000000000000000009189 170.0
TH3_k127_7166032_11 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000479 158.0
TH3_k127_7166032_12 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000002362 123.0
TH3_k127_7166032_13 domain protein K12516 - - 0.00000000000000000000000000006068 130.0
TH3_k127_7166032_14 Binds the 23S rRNA K02909 - - 0.000000000000000000000000006809 110.0
TH3_k127_7166032_15 FAD binding domain K00278 - 1.4.3.16 0.00000000000000000004994 92.0
TH3_k127_7166032_16 Protein of unknown function DUF262 - - - 0.0000000000000004418 81.0
TH3_k127_7166032_17 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000751 70.0
TH3_k127_7166032_18 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000001273 65.0
TH3_k127_7166032_19 ACT domain protein - - - 0.00001672 54.0
TH3_k127_7166032_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 504.0
TH3_k127_7166032_20 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00002869 48.0
TH3_k127_7166032_3 membrane protein involved in D-alanine export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 492.0
TH3_k127_7166032_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 476.0
TH3_k127_7166032_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 483.0
TH3_k127_7166032_6 metal-dependent enzyme K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 302.0
TH3_k127_7166032_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000007231 252.0
TH3_k127_7166032_8 - - - - 0.0000000000000000000000000000000000000000000000004486 192.0
TH3_k127_7166032_9 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000001681 179.0
TH3_k127_7242644_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1329.0
TH3_k127_72800_0 UDP binding domain K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 426.0
TH3_k127_72800_1 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000009568 151.0
TH3_k127_72800_2 Nucleotidyltransferase domain K07076 - - 0.000000003289 63.0
TH3_k127_72800_3 PFAM VanZ family protein - - - 0.000001013 61.0
TH3_k127_72800_4 PFAM CopG domain protein DNA-binding domain protein - - - 0.0001454 46.0
TH3_k127_7315067_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.381e-200 631.0
TH3_k127_7315067_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 385.0
TH3_k127_7315067_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000003368 184.0
TH3_k127_7315067_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000001258 144.0
TH3_k127_7315067_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000791 89.0
TH3_k127_7370606_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 417.0
TH3_k127_7454563_0 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 445.0
TH3_k127_7454563_1 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 344.0
TH3_k127_7454563_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006097 274.0
TH3_k127_7454563_3 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.0000000000000000000000000000003936 122.0
TH3_k127_7461779_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 549.0
TH3_k127_7461779_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00001884 48.0
TH3_k127_7475046_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 406.0
TH3_k127_7475046_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 407.0
TH3_k127_747584_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 388.0
TH3_k127_747584_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 330.0
TH3_k127_747584_2 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000009099 192.0
TH3_k127_747584_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000002722 148.0
TH3_k127_747584_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000001312 96.0
TH3_k127_7487411_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.804e-195 621.0
TH3_k127_7487411_1 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 396.0
TH3_k127_7487411_2 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002199 288.0
TH3_k127_7487411_3 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000158 247.0
TH3_k127_7487411_4 STAS domain K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000006931 248.0
TH3_k127_7487411_5 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000001214 170.0
TH3_k127_7487411_6 - - - - 0.00000000000000000000000000000000001161 146.0
TH3_k127_7496403_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.999e-262 820.0
TH3_k127_7496403_1 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 1.442e-217 698.0
TH3_k127_7496403_10 protein-disulfide reductase activity - - - 0.0000000000000000000000000006155 119.0
TH3_k127_7496403_11 - - - - 0.00000000000004508 80.0
TH3_k127_7496403_12 4Fe-4S binding domain - - - 0.0000001058 56.0
TH3_k127_7496403_2 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 401.0
TH3_k127_7496403_3 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 294.0
TH3_k127_7496403_4 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000646 285.0
TH3_k127_7496403_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000001687 226.0
TH3_k127_7496403_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000005376 207.0
TH3_k127_7496403_7 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000003874 204.0
TH3_k127_7496403_8 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000841 177.0
TH3_k127_7496403_9 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000001333 142.0
TH3_k127_7512662_0 Calcineurin-like phosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 361.0
TH3_k127_7512662_1 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 325.0
TH3_k127_7512662_2 - - - - 0.0000000000000000000000000000000000000000000004722 184.0
TH3_k127_7512662_3 PFAM Transposase K07491 - - 0.00000000000000000000000000000002518 127.0
TH3_k127_7512662_4 PFAM Plasmid maintenance system killer K07334 - - 0.00000000000000000000000000000006509 126.0
TH3_k127_7512662_5 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.000000000000000000000000000001794 123.0
TH3_k127_7512662_6 sequence-specific DNA binding - - - 0.00000000000000000000000000001942 119.0
TH3_k127_7512662_7 sequence-specific DNA binding - - - 0.00000000000000000000000000158 114.0
TH3_k127_7512662_8 Transposase DDE domain - - - 0.000000000000001308 76.0
TH3_k127_7521237_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.043e-271 849.0
TH3_k127_7521237_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 1.148e-225 717.0
TH3_k127_7521237_10 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000001387 220.0
TH3_k127_7521237_11 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000006557 217.0
TH3_k127_7521237_12 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000466 200.0
TH3_k127_7521237_13 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000008189 184.0
TH3_k127_7521237_14 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000001932 177.0
TH3_k127_7521237_15 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000008081 155.0
TH3_k127_7521237_16 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000004107 150.0
TH3_k127_7521237_17 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000000000006443 123.0
TH3_k127_7521237_18 protein complex oligomerization - - - 0.00000000000000000768 89.0
TH3_k127_7521237_19 SMART Cold shock protein K03704 - - 0.00000000000002527 73.0
TH3_k127_7521237_2 Aminotransferase class-III K01845 - 5.4.3.8 1.304e-199 629.0
TH3_k127_7521237_20 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000006455 65.0
TH3_k127_7521237_22 Transposase IS200 like K07491 - - 0.0004395 45.0
TH3_k127_7521237_3 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 610.0
TH3_k127_7521237_4 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 563.0
TH3_k127_7521237_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 430.0
TH3_k127_7521237_6 PFAM 4Fe-4S K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 421.0
TH3_k127_7521237_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 342.0
TH3_k127_7521237_8 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000227 269.0
TH3_k127_7521237_9 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005699 245.0
TH3_k127_7534166_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 414.0
TH3_k127_7534166_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 379.0
TH3_k127_7534166_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 369.0
TH3_k127_7534166_3 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003002 287.0
TH3_k127_7534166_4 reverse transcriptase K00986 - 2.7.7.49 0.000000000000000000000000000001119 128.0
TH3_k127_7534166_5 Exonuclease VII small subunit K03602 - 3.1.11.6 0.00000000000003556 76.0
TH3_k127_753556_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1367.0
TH3_k127_753556_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 312.0
TH3_k127_753556_2 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003629 266.0
TH3_k127_7541126_0 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 379.0
TH3_k127_7541126_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007088 250.0
TH3_k127_7541126_10 Protein of unknown function (DUF1353) - - - 0.00007901 46.0
TH3_k127_7541126_2 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000007837 220.0
TH3_k127_7541126_3 PFAM Phosphoglycerate mutase K08296 - - 0.0000000000000000000000000000000000000000000000000000131 192.0
TH3_k127_7541126_4 HicB family - - - 0.0000000000000000000000000000000000000354 145.0
TH3_k127_7541126_5 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000006723 109.0
TH3_k127_7541126_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000005309 83.0
TH3_k127_7541126_7 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000002551 68.0
TH3_k127_7541126_8 Protein of unknown function (DUF1353) - - - 0.00001114 53.0
TH3_k127_7541126_9 - - - - 0.00003399 52.0
TH3_k127_7571228_0 ABC transporter K06020 - 3.6.3.25 9.789e-256 793.0
TH3_k127_7571228_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 640.0
TH3_k127_7571228_10 Macrocin-O-methyltransferase (TylF) K05303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000612 285.0
TH3_k127_7571228_11 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003687 280.0
TH3_k127_7571228_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002885 244.0
TH3_k127_7571228_13 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000005362 198.0
TH3_k127_7571228_14 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000009332 186.0
TH3_k127_7571228_15 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000002864 181.0
TH3_k127_7571228_16 Glycosyltransferase like family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000002975 186.0
TH3_k127_7571228_17 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000006558 173.0
TH3_k127_7571228_18 Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000009527 180.0
TH3_k127_7571228_19 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000003896 178.0
TH3_k127_7571228_2 ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 451.0
TH3_k127_7571228_20 PFAM Glycosyl transferase family 2 K12992 - - 0.000000000000000000000000000000000001646 153.0
TH3_k127_7571228_21 Methyltransferase domain - - - 0.0000000000000000000000000000001118 133.0
TH3_k127_7571228_22 methyltransferase activity K02169 - 2.1.1.197 0.000000000000000000000000008582 122.0
TH3_k127_7571228_23 Elongation factor G C-terminus K06207 - - 0.00000000000000009143 80.0
TH3_k127_7571228_24 NAD(P)H-binding K01709,K01710 - 4.2.1.45,4.2.1.46 0.0003512 47.0
TH3_k127_7571228_3 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 419.0
TH3_k127_7571228_4 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 386.0
TH3_k127_7571228_5 Transport permease protein K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 359.0
TH3_k127_7571228_6 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 347.0
TH3_k127_7571228_7 PFAM Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 328.0
TH3_k127_7571228_8 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 333.0
TH3_k127_7571228_9 carbohydrate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 306.0
TH3_k127_7574247_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 571.0
TH3_k127_7574247_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 546.0
TH3_k127_7574247_2 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 469.0
TH3_k127_7574247_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 463.0
TH3_k127_7574247_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 456.0
TH3_k127_7574247_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 428.0
TH3_k127_7574247_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000008728 198.0
TH3_k127_7574247_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000002418 177.0
TH3_k127_7574247_8 response regulator receiver - - - 0.00000000000000000000000000000000000000001781 158.0
TH3_k127_7574247_9 dna polymerase III K02342 - 2.7.7.7 0.00000000000000000000000001285 117.0
TH3_k127_7605869_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 303.0
TH3_k127_7605869_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002555 223.0
TH3_k127_7605869_2 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000366 184.0
TH3_k127_7605869_3 sulfur relay protein, TusE DsrC DsvC family K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000001124 107.0
TH3_k127_7605869_4 Hemerythrin HHE cation binding domain - - - 0.00000000000659 67.0
TH3_k127_7616682_0 Transposase for insertion sequence element - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007316 272.0
TH3_k127_7616682_1 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000001083 196.0
TH3_k127_7643990_0 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 532.0
TH3_k127_7643990_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000188 204.0
TH3_k127_7643990_2 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000008996 187.0
TH3_k127_7643990_3 RDD family - - - 0.0000000000000000000000000005881 118.0
TH3_k127_7643990_4 TIGRFAM rod shape-determining protein MreD K03571 - - 0.00008087 49.0
TH3_k127_7643993_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 500.0
TH3_k127_7643993_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 423.0
TH3_k127_7643993_2 rod shape-determining protein MreD K03571 - - 0.0001744 49.0
TH3_k127_7663312_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.255e-255 799.0
TH3_k127_7663312_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 314.0
TH3_k127_7663312_2 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003712 276.0
TH3_k127_7663312_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001722 247.0
TH3_k127_7663312_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000004357 182.0
TH3_k127_7663312_5 His Kinase A (phosphoacceptor) domain K14982 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000007364 142.0
TH3_k127_7663879_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 336.0
TH3_k127_7663879_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002174 263.0
TH3_k127_7663879_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000001636 79.0
TH3_k127_7663879_3 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000008658 59.0
TH3_k127_7682696_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 566.0
TH3_k127_7682696_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 366.0
TH3_k127_7682696_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 298.0
TH3_k127_7682696_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000004878 214.0
TH3_k127_7731891_0 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 364.0
TH3_k127_7731891_1 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000001013 175.0
TH3_k127_7759481_0 all-trans-retinol 13,14-reductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 569.0
TH3_k127_7759481_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 473.0
TH3_k127_7759481_10 - - - - 0.000000000000000000000002609 105.0
TH3_k127_7759481_11 Outer membrane efflux protein - - - 0.0000002273 58.0
TH3_k127_7759481_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 366.0
TH3_k127_7759481_3 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 298.0
TH3_k127_7759481_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001327 238.0
TH3_k127_7759481_5 NosL - - - 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
TH3_k127_7759481_6 NosL - - - 0.0000000000000000000000000000000000000000000009241 171.0
TH3_k127_7759481_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000163 170.0
TH3_k127_7759481_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000001856 151.0
TH3_k127_7759481_9 - - - - 0.00000000000000000000000000000000000615 142.0
TH3_k127_7761124_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000851 277.0
TH3_k127_7761124_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000007186 211.0
TH3_k127_7761124_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000001939 220.0
TH3_k127_7761124_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000008746 212.0
TH3_k127_7761124_4 - - - - 0.000000000000000000000001879 117.0
TH3_k127_7787759_0 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 335.0
TH3_k127_7787759_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 313.0
TH3_k127_7787759_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005859 273.0
TH3_k127_7787759_3 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002641 262.0
TH3_k127_7787759_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007278 249.0
TH3_k127_7787759_5 PFAM peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000179 248.0
TH3_k127_7787759_6 PFAM PHP domain - - - 0.00000000000000000000000000000000000005198 151.0
TH3_k127_7852233_0 Baseplate J-like protein - - - 0.0 1212.0
TH3_k127_7852233_1 protein of Photorhabdus and some similarities with - - - 2.623e-301 947.0
TH3_k127_7852233_10 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002272 280.0
TH3_k127_7852233_11 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004389 274.0
TH3_k127_7852233_12 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000584 247.0
TH3_k127_7852233_13 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000001742 247.0
TH3_k127_7852233_14 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000000000000000000000000002184 213.0
TH3_k127_7852233_15 PAAR repeat-containing protein - - - 0.00000000000000000000000000000008123 126.0
TH3_k127_7852233_16 - - - - 0.000000000000003561 76.0
TH3_k127_7852233_17 endonuclease containing a URI domain K07461 - - 0.0000000000002749 73.0
TH3_k127_7852233_18 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.00000000004086 69.0
TH3_k127_7852233_19 - - - - 0.0000001599 55.0
TH3_k127_7852233_2 Phage late control gene D protein (GPD) - - - 2.341e-270 844.0
TH3_k127_7852233_3 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 588.0
TH3_k127_7852233_4 citrate synthase K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 402.0
TH3_k127_7852233_5 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 386.0
TH3_k127_7852233_6 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 362.0
TH3_k127_7852233_7 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 351.0
TH3_k127_7852233_8 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 307.0
TH3_k127_7852233_9 Virulence factor BrkB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 297.0
TH3_k127_7860923_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000023 238.0
TH3_k127_7860923_1 NosL - - - 0.0000000000000000000000000000000000000000000000007364 180.0
TH3_k127_7860923_2 Thioredoxin-like - - - 0.00000000000000000000000000000001863 132.0
TH3_k127_7860923_3 - - - - 0.0000000000000000000597 93.0
TH3_k127_7860923_4 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000007542 89.0
TH3_k127_7881707_0 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 336.0
TH3_k127_7881707_1 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 286.0
TH3_k127_7881707_2 belongs to the Fur family K02076,K03711,K09823 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000001878 103.0
TH3_k127_7881707_3 ABC 3 transport family K09816 - - 0.00000000000000000002278 92.0
TH3_k127_7881707_4 Belongs to the Fur family K02076,K03711 GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000003726 79.0
TH3_k127_7909338_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 516.0
TH3_k127_7909338_1 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 540.0
TH3_k127_7909338_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00002283 49.0
TH3_k127_7909338_2 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 545.0
TH3_k127_7909338_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 459.0
TH3_k127_7909338_4 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 418.0
TH3_k127_7909338_5 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 289.0
TH3_k127_7909338_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 294.0
TH3_k127_7909338_7 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000006006 222.0
TH3_k127_7909338_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000001869 153.0
TH3_k127_7909338_9 UTRA K03710 - - 0.00000000000000000000000000000000312 138.0
TH3_k127_7953296_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.557e-285 897.0
TH3_k127_7953296_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 7.329e-266 844.0
TH3_k127_7953296_10 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 335.0
TH3_k127_7953296_11 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 328.0
TH3_k127_7953296_12 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 322.0
TH3_k127_7953296_13 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006013 284.0
TH3_k127_7953296_14 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006342 282.0
TH3_k127_7953296_15 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000001346 240.0
TH3_k127_7953296_16 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000008653 239.0
TH3_k127_7953296_17 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000008868 221.0
TH3_k127_7953296_18 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000006311 196.0
TH3_k127_7953296_19 MarC family integral membrane protein - - - 0.0000000000000000000000000000000000000000000006026 172.0
TH3_k127_7953296_2 DNA polymerase A domain K02335 - 2.7.7.7 2.47e-265 843.0
TH3_k127_7953296_20 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000001843 161.0
TH3_k127_7953296_21 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000006162 159.0
TH3_k127_7953296_22 Sh3 type 3 domain protein K02450,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000212 151.0
TH3_k127_7953296_23 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000001049 118.0
TH3_k127_7953296_24 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000396 92.0
TH3_k127_7953296_25 assembly protein PilO K02664 - - 0.0000000000002365 78.0
TH3_k127_7953296_26 PFAM phosphate transporter K03306 - - 0.00000000001717 67.0
TH3_k127_7953296_27 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000008631 57.0
TH3_k127_7953296_28 Pilus assembly protein, PilP K02665 - - 0.00000006996 62.0
TH3_k127_7953296_29 Phosphate transporter family K03306 - - 0.00000272 54.0
TH3_k127_7953296_3 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 8.941e-256 808.0
TH3_k127_7953296_30 Protein of unknown function (DUF721) - - - 0.0000107 54.0
TH3_k127_7953296_31 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.00002288 53.0
TH3_k127_7953296_32 Peptidase M56 - - - 0.00003676 55.0
TH3_k127_7953296_33 PFAM Fimbrial assembly family protein K02663 - - 0.00006241 52.0
TH3_k127_7953296_4 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 8.782e-213 685.0
TH3_k127_7953296_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 583.0
TH3_k127_7953296_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 456.0
TH3_k127_7953296_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 403.0
TH3_k127_7953296_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 392.0
TH3_k127_7953296_9 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 341.0
TH3_k127_7964117_0 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 335.0
TH3_k127_7964117_1 Protein of unknown function K09800 - - 0.000000000000000000001321 110.0
TH3_k127_7991594_0 PHP-associated K07053 - 3.1.3.97 0.00000000000000000000000000000000000002223 148.0
TH3_k127_7991594_1 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000008356 98.0
TH3_k127_8003668_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 367.0
TH3_k127_8003668_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000004799 246.0
TH3_k127_8003668_10 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000005612 76.0
TH3_k127_8003668_2 LysM domain K01449,K19223 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000008667 250.0
TH3_k127_8003668_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000004668 178.0
TH3_k127_8003668_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000001724 141.0
TH3_k127_8003668_5 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000000000000006402 142.0
TH3_k127_8003668_6 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000001025 103.0
TH3_k127_8003668_7 metalloendopeptidase activity K03799 - - 0.0000000000000000001446 98.0
TH3_k127_8003668_8 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000169 87.0
TH3_k127_8003668_9 NusG domain II K00805 - 2.5.1.30 0.00000000000000005529 86.0
TH3_k127_8028968_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 335.0
TH3_k127_8028968_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 325.0
TH3_k127_8028968_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 285.0
TH3_k127_8028968_3 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000000000000000000374 201.0
TH3_k127_8028968_4 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000004646 160.0
TH3_k127_8028968_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000001854 57.0
TH3_k127_8063348_0 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000002494 207.0
TH3_k127_8063348_1 - - - - 0.000000005688 62.0
TH3_k127_8102728_0 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 358.0
TH3_k127_8102728_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 338.0
TH3_k127_8102728_2 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000006393 225.0
TH3_k127_8102728_3 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000002259 174.0
TH3_k127_8102728_4 glycosyl transferase group 1 - - - 0.000000000000000000000000000000004032 143.0
TH3_k127_8102728_5 transferase activity, transferring glycosyl groups - - - 0.00000000004396 68.0
TH3_k127_8179641_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 2.688e-196 622.0
TH3_k127_8179641_1 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 564.0
TH3_k127_8179641_10 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000000001615 98.0
TH3_k127_8179641_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000005786 99.0
TH3_k127_8179641_12 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000004176 60.0
TH3_k127_8179641_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 535.0
TH3_k127_8179641_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000005167 206.0
TH3_k127_8179641_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000003387 156.0
TH3_k127_8179641_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000002804 129.0
TH3_k127_8179641_7 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000004057 130.0
TH3_k127_8179641_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000000000004869 119.0
TH3_k127_8179641_9 LysM domain - - - 0.000000000000000000000000001135 124.0
TH3_k127_8203937_0 response regulator K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 336.0
TH3_k127_8203937_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000005018 244.0
TH3_k127_8242735_0 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000008674 238.0
TH3_k127_8242735_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000001956 217.0
TH3_k127_8242735_2 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000005428 182.0
TH3_k127_8242735_3 receptor K16092 - - 0.00004849 48.0
TH3_k127_8258290_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 5.018e-213 671.0
TH3_k127_8258290_1 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 384.0
TH3_k127_8258290_2 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000002758 175.0
TH3_k127_8258290_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.000000000001178 71.0
TH3_k127_8288474_0 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 577.0
TH3_k127_8288474_1 DEAD DEAH box helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 465.0
TH3_k127_8288474_10 SEC-C Motif Domain Protein - - - 0.00000000627 65.0
TH3_k127_8288474_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003157 269.0
TH3_k127_8288474_3 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000002292 206.0
TH3_k127_8288474_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000002441 149.0
TH3_k127_8288474_5 Peptidase M15 K02395 - - 0.0000000000000000000000000000000000006604 146.0
TH3_k127_8288474_6 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000001056 126.0
TH3_k127_8288474_7 - - - - 0.00000000000000000002098 104.0
TH3_k127_8288474_8 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000001312 88.0
TH3_k127_8316022_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 1.734e-215 674.0
TH3_k127_8316022_1 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 596.0
TH3_k127_8316022_2 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 518.0
TH3_k127_8316022_3 MazG family K02428,K02499 - 3.6.1.66 0.000000000000000000000000000000000444 134.0
TH3_k127_8316022_4 ThiS family K03636 - - 0.0000000000000000000000000000000006907 132.0
TH3_k127_8316022_5 NIL - - - 0.0000000000000000000000000002248 115.0
TH3_k127_8316022_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000003569 115.0
TH3_k127_8353976_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 473.0
TH3_k127_8353976_1 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 377.0
TH3_k127_8353976_11 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.00000000000001353 81.0
TH3_k127_8353976_2 ABC-type polysaccharide polyol phosphate transport system ATPase component K09689 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 287.0
TH3_k127_8353976_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001631 280.0
TH3_k127_8353976_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004896 281.0
TH3_k127_8353976_5 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000006593 239.0
TH3_k127_8353976_6 Transport Permease Protein K09688 - - 0.0000000000000000000000000000000000000000000000000000000000000001815 229.0
TH3_k127_8353976_7 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000002261 178.0
TH3_k127_8353976_8 COG3524 Capsule polysaccharide export protein K10107 - - 0.00000000000000000000000000000000000000000000003237 177.0
TH3_k127_8353976_9 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000004005 149.0
TH3_k127_8387112_0 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 361.0
TH3_k127_8387112_2 Virulence factor BrkB K07058 - - 0.0006693 43.0
TH3_k127_8392488_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000002513 239.0
TH3_k127_8392488_1 SMART HNH nuclease K07451 - - 0.0000000000000000000000000000000000000000082 155.0
TH3_k127_8392488_2 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000001265 156.0
TH3_k127_8392488_3 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000001717 118.0
TH3_k127_8392488_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000797 102.0
TH3_k127_8392488_5 Protein of unknown function (DUF507) - - - 0.00000000000000000000002089 102.0
TH3_k127_8392488_6 Putative methyltransferase - - - 0.000000000002628 78.0
TH3_k127_8449133_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 604.0
TH3_k127_846664_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 1.447e-292 915.0
TH3_k127_846664_1 cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 392.0
TH3_k127_846664_2 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 290.0
TH3_k127_846664_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003358 303.0
TH3_k127_846664_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000001416 148.0
TH3_k127_846664_5 - - - - 0.00000000000000000000000000000000004135 154.0
TH3_k127_846664_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000001112 122.0
TH3_k127_846664_7 chlorophyll binding K03286,K03640 - - 0.000000001171 64.0
TH3_k127_846664_8 Protein of unknown function (DUF2950) - - - 0.000000001762 58.0
TH3_k127_8475730_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 379.0
TH3_k127_8475730_1 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001602 246.0
TH3_k127_8475730_2 COGs COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000008605 200.0
TH3_k127_8475730_3 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000025 161.0
TH3_k127_8475730_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000003446 69.0
TH3_k127_8475730_5 Alpha beta hydrolase - - - 0.000001661 55.0
TH3_k127_8511775_0 ABC transporter K03701 - - 0.0 1015.0
TH3_k127_8511775_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 335.0
TH3_k127_8511775_2 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.00000000000000000000000000000006251 130.0
TH3_k127_8626533_0 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 442.0
TH3_k127_8626533_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 390.0
TH3_k127_8626533_10 EVE domain - - - 0.000000000000000000000000003707 113.0
TH3_k127_8626533_11 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000001487 109.0
TH3_k127_8626533_12 Transposase IS200 like K07491 - - 0.000000000000000000000000984 105.0
TH3_k127_8626533_13 Homeodomain-like domain - - - 0.000000000000000000000001799 108.0
TH3_k127_8626533_14 PBP superfamily domain K05772 - - 0.0000000000000000000003605 98.0
TH3_k127_8626533_15 COG2801 Transposase and inactivated derivatives - - - 0.00000000004185 66.0
TH3_k127_8626533_16 Glucose / Sorbosone dehydrogenase K00428,K01728 - 1.11.1.5,4.2.2.2 0.00000001146 65.0
TH3_k127_8626533_2 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 385.0
TH3_k127_8626533_3 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 349.0
TH3_k127_8626533_4 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 304.0
TH3_k127_8626533_5 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000001674 245.0
TH3_k127_8626533_6 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000001875 230.0
TH3_k127_8626533_7 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000005925 215.0
TH3_k127_8626533_8 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000003104 159.0
TH3_k127_8626533_9 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000000000001038 139.0
TH3_k127_8683542_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 617.0
TH3_k127_8683542_1 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 295.0
TH3_k127_8683542_2 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 301.0
TH3_k127_8683542_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000003255 229.0
TH3_k127_8683542_4 Pyridoxal-phosphate dependent enzyme K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000007671 234.0
TH3_k127_8683542_5 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000009119 204.0
TH3_k127_8720461_0 Aconitase C-terminal domain K01681 - 4.2.1.3 6.838e-294 915.0
TH3_k127_8720461_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 533.0
TH3_k127_8720461_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000007826 117.0
TH3_k127_8787440_0 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000005983 178.0
TH3_k127_8787440_1 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000009552 156.0
TH3_k127_8787440_2 TIGRFAM methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.00000397 49.0
TH3_k127_8792249_0 PD-(D/E)XK nuclease superfamily - - - 1.481e-229 749.0
TH3_k127_8792249_1 Belongs to the helicase family. UvrD subfamily - - - 4.19e-211 688.0
TH3_k127_8792249_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000001699 116.0
TH3_k127_8792249_3 sequence-specific DNA binding - - - 0.0000000000000000003202 88.0
TH3_k127_8792249_4 PIN domain - - - 0.00000000178 66.0
TH3_k127_8792249_5 Staphylococcal nuclease homologues - - - 0.00000002555 59.0
TH3_k127_8792249_6 Staphylococcal nuclease homologues - - - 0.000005076 51.0
TH3_k127_8796174_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 577.0
TH3_k127_8796174_1 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 290.0
TH3_k127_8796174_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000003546 229.0
TH3_k127_8796174_3 Iron-storage protein K02217 - 1.16.3.2 0.00000004526 54.0
TH3_k127_8802999_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 311.0
TH3_k127_8802999_1 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001009 270.0
TH3_k127_8802999_2 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000002284 205.0
TH3_k127_8802999_3 MlaD protein K02067 - - 0.000000000000000000000000001597 123.0
TH3_k127_8802999_4 STAS domain K04749 - - 0.0000000000000000002721 91.0
TH3_k127_8802999_5 Sigma factor PP2C-like phosphatases - - - 0.00000002273 56.0
TH3_k127_8802999_6 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0002141 51.0
TH3_k127_8831195_0 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 320.0
TH3_k127_8831195_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000003217 223.0
TH3_k127_8841588_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 3317.0
TH3_k127_8841588_1 Belongs to the universal stress protein A family - - - 0.000000005786 59.0
TH3_k127_8860258_0 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 570.0
TH3_k127_8860258_1 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 560.0
TH3_k127_8860258_2 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 393.0
TH3_k127_8860674_0 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 502.0
TH3_k127_8860674_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 468.0
TH3_k127_8860674_2 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 364.0
TH3_k127_8860674_3 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000107 269.0
TH3_k127_8860674_4 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000000008884 149.0
TH3_k127_8860674_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000001064 137.0
TH3_k127_8860674_6 cell redox homeostasis - - - 0.000000000000000000000006282 102.0
TH3_k127_8860674_7 multicopper oxidases K06324 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.16.3.3 0.00000000000000000000001307 109.0
TH3_k127_8860674_8 - - - - 0.00000000000000000002643 96.0
TH3_k127_8886176_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 591.0
TH3_k127_8886176_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 338.0
TH3_k127_8886176_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 308.0
TH3_k127_8886176_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000003743 256.0
TH3_k127_8897734_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 414.0
TH3_k127_8897734_1 Histidine kinase K10125 - 2.7.13.3 0.00000000000000000000000000000000000002296 156.0
TH3_k127_8897734_2 Methyltransferase domain - - - 0.0000000000000000000000000007526 123.0
TH3_k127_8905400_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0 1197.0
TH3_k127_8905400_1 Iron-sulfur cluster-binding domain K06871 - - 3.12e-220 689.0
TH3_k127_8905400_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 394.0
TH3_k127_8905400_3 - - - - 0.0000000000000000000000271 105.0
TH3_k127_8905400_4 AAA domain - - - 0.00003453 46.0
TH3_k127_8922516_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.175e-310 970.0
TH3_k127_8922516_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.807e-297 931.0
TH3_k127_8922516_10 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000009126 161.0
TH3_k127_8922516_11 translation release factor activity - - - 0.00000000000000000000000000000000000002698 147.0
TH3_k127_8922516_12 DivIVA protein K04074 - - 0.000000000000000000000000004464 117.0
TH3_k127_8922516_13 ATP cone domain - - - 0.000000000000000000005875 96.0
TH3_k127_8922516_14 - - - - 0.000000000000000000009419 98.0
TH3_k127_8922516_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.596e-196 619.0
TH3_k127_8922516_3 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 498.0
TH3_k127_8922516_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 436.0
TH3_k127_8922516_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 403.0
TH3_k127_8922516_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 336.0
TH3_k127_8922516_7 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001861 283.0
TH3_k127_8922516_8 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000001418 244.0
TH3_k127_8922516_9 - - - - 0.00000000000000000000000000000000000000000000000000000001357 207.0
TH3_k127_894544_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 587.0
TH3_k127_894544_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 495.0
TH3_k127_894544_10 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000000000000000000000000000000000000000000000000003558 209.0
TH3_k127_894544_11 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000002059 216.0
TH3_k127_894544_12 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.000000000000000000000000000000000000000000000000005357 189.0
TH3_k127_894544_13 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000005467 190.0
TH3_k127_894544_14 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000004578 193.0
TH3_k127_894544_15 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000006277 172.0
TH3_k127_894544_16 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000017 172.0
TH3_k127_894544_17 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000003315 127.0
TH3_k127_894544_18 Protein of unknown function (DUF2905) - - - 0.0000000000000000001249 92.0
TH3_k127_894544_19 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000005733 89.0
TH3_k127_894544_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 471.0
TH3_k127_894544_20 - - - - 0.000000000000003052 79.0
TH3_k127_894544_21 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000007846 64.0
TH3_k127_894544_22 ATP-binding region, ATPase domain protein K10916 - 2.7.13.3 0.00000001067 64.0
TH3_k127_894544_24 - - - - 0.000006437 49.0
TH3_k127_894544_25 PFAM Sporulation domain protein - - - 0.0001582 52.0
TH3_k127_894544_3 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 424.0
TH3_k127_894544_4 Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 407.0
TH3_k127_894544_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 390.0
TH3_k127_894544_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 355.0
TH3_k127_894544_7 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 298.0
TH3_k127_894544_8 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02236,K02278,K02506,K02654,K10966 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000007359 253.0
TH3_k127_894544_9 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000001085 219.0
TH3_k127_8953726_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 343.0
TH3_k127_8953726_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000003037 224.0
TH3_k127_8953726_2 PFAM PQ loop repeat K15383 - - 0.0000000000000000000000000001711 119.0
TH3_k127_8953726_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000003105 117.0
TH3_k127_8953726_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0002758 45.0
TH3_k127_9009166_0 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 398.0
TH3_k127_9009166_1 pilus organization K07346 - - 0.000000000000000000000000000000000000000000000000003735 191.0
TH3_k127_9009166_2 Spore Coat Protein U domain - - - 0.00000000000000000000004137 106.0
TH3_k127_9009166_3 Spore Coat Protein - - - 0.00000000000000000004616 96.0
TH3_k127_9009166_4 GGDEF domain - - - 0.00000000000002281 73.0
TH3_k127_9012813_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 385.0
TH3_k127_9012813_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 355.0
TH3_k127_9012813_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 317.0
TH3_k127_9012813_3 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 310.0
TH3_k127_9012813_4 PFAM UbiA prenyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000329 215.0
TH3_k127_9012813_5 Glycosyl transferases group 1 - - - 0.00000006238 55.0
TH3_k127_9059742_0 Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 375.0
TH3_k127_9059742_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000002779 171.0
TH3_k127_9059742_2 WYL domain K13572 - - 0.000000000000000000000000000002554 132.0
TH3_k127_9059742_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000205 50.0
TH3_k127_9092808_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1063.0
TH3_k127_9092808_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 544.0
TH3_k127_9092808_10 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001303 263.0
TH3_k127_9092808_11 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000001653 237.0
TH3_k127_9092808_12 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000005363 219.0
TH3_k127_9092808_13 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000003068 198.0
TH3_k127_9092808_14 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000044 189.0
TH3_k127_9092808_15 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000006327 145.0
TH3_k127_9092808_16 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000001109 143.0
TH3_k127_9092808_17 OstA-like protein K09774 - - 0.0000000000000000000000000000000003381 136.0
TH3_k127_9092808_18 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.00000000000000000000000000000001355 135.0
TH3_k127_9092808_19 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000002564 138.0
TH3_k127_9092808_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 505.0
TH3_k127_9092808_20 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000003362 88.0
TH3_k127_9092808_21 Permeases of the drug metabolite transporter (DMT) K03298 - - 0.000000000000005831 85.0
TH3_k127_9092808_22 Pilus assembly protein K02461,K02662,K02663,K12288,K12289 GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000007978 61.0
TH3_k127_9092808_23 Mammalian cell entry related domain protein K02067 - - 0.0000139 52.0
TH3_k127_9092808_24 Lipopolysaccharide-assembly, LptC-related - - - 0.0001912 50.0
TH3_k127_9092808_25 Psort location Cytoplasmic, score - - - 0.0003865 49.0
TH3_k127_9092808_26 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0005502 47.0
TH3_k127_9092808_3 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 376.0
TH3_k127_9092808_4 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 352.0
TH3_k127_9092808_5 Bacterial type II and III secretion system protein K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 360.0
TH3_k127_9092808_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 329.0
TH3_k127_9092808_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 292.0
TH3_k127_9092808_8 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 292.0
TH3_k127_9092808_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003252 275.0
TH3_k127_9200661_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 385.0
TH3_k127_9200661_1 Trypsin - - - 0.0000000000000000002097 98.0
TH3_k127_9200661_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000003007 83.0
TH3_k127_9200661_3 CYTH K05873 - 4.6.1.1 0.000000000128 69.0
TH3_k127_9268128_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 603.0
TH3_k127_9268128_1 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 325.0
TH3_k127_9268128_2 Transglutaminase-like superfamily - - - 0.0000000000000000000001028 112.0
TH3_k127_9268128_3 peptidyl-tyrosine sulfation - - - 0.0000000008618 71.0
TH3_k127_9268128_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000695 46.0
TH3_k127_9279953_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000004981 237.0
TH3_k127_9279953_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000007018 154.0
TH3_k127_9279953_2 Glu-tRNAGln amidotransferase C subunit K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000004825 115.0
TH3_k127_9318729_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.948e-256 796.0
TH3_k127_9318729_1 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 355.0
TH3_k127_9318729_2 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0000000000000000000000000000000000000000001625 160.0
TH3_k127_9318729_3 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000001316 78.0
TH3_k127_9366092_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 465.0
TH3_k127_9366092_1 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 381.0
TH3_k127_9366092_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001406 279.0
TH3_k127_9366092_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000006871 158.0
TH3_k127_9366092_4 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000007806 152.0
TH3_k127_9366092_5 Tetratricopeptide repeat - - - 0.0000004732 63.0
TH3_k127_9399399_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 442.0
TH3_k127_9399399_1 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 374.0
TH3_k127_9399399_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000001318 256.0
TH3_k127_9399399_4 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000002014 236.0
TH3_k127_9399399_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000007836 184.0
TH3_k127_9399399_6 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000003069 190.0
TH3_k127_9399399_7 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000012 125.0
TH3_k127_9399399_8 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000001829 127.0
TH3_k127_9399399_9 ORF6N domain - - - 0.0003504 43.0
TH3_k127_9411849_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 437.0
TH3_k127_9411849_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001931 261.0
TH3_k127_9411849_10 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.0000000001006 62.0
TH3_k127_9411849_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000004209 69.0
TH3_k127_9411849_12 - K06039,K07092 - - 0.000005481 56.0
TH3_k127_9411849_2 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000006919 200.0
TH3_k127_9411849_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000000000000009774 198.0
TH3_k127_9411849_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000002803 182.0
TH3_k127_9411849_5 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000000001202 145.0
TH3_k127_9411849_6 Protein of unknown function DUF134 - - - 0.00000000000000000000000002377 111.0
TH3_k127_9411849_7 PIN domain - - - 0.000000000000000000000005872 106.0
TH3_k127_9411849_8 ORF6N domain - - - 0.00000000000000000000008126 100.0
TH3_k127_9411849_9 PFAM SpoVT AbrB - - - 0.0000000000000001253 81.0
TH3_k127_9487543_0 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 326.0
TH3_k127_9487543_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 289.0
TH3_k127_9487543_2 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001075 291.0
TH3_k127_9487543_3 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000006109 94.0
TH3_k127_9488034_0 Phosphoglycerate kinase K00927 - 2.7.2.3 4.059e-195 615.0
TH3_k127_9488034_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 549.0
TH3_k127_9488034_10 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000003299 237.0
TH3_k127_9488034_11 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000002499 230.0
TH3_k127_9488034_12 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000009654 209.0
TH3_k127_9488034_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000553 213.0
TH3_k127_9488034_14 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000007959 196.0
TH3_k127_9488034_15 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000001194 167.0
TH3_k127_9488034_16 NTPase - - - 0.0000000000000000000000000000000000000002889 156.0
TH3_k127_9488034_17 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000003113 146.0
TH3_k127_9488034_18 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000000000552 104.0
TH3_k127_9488034_19 Protein of unknown function (DUF3617) - - - 0.00000000000000000000007045 105.0
TH3_k127_9488034_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 488.0
TH3_k127_9488034_20 PFAM Disulphide bond isomerase, DsbC G-like K03981 - 5.3.4.1 0.00000000005278 72.0
TH3_k127_9488034_21 Uncharacterised protein family (UPF0158) - - - 0.0000000001783 69.0
TH3_k127_9488034_22 iron-sulfur cluster assembly - - - 0.00004127 47.0
TH3_k127_9488034_3 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 475.0
TH3_k127_9488034_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 426.0
TH3_k127_9488034_5 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 411.0
TH3_k127_9488034_6 PFAM Cys Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 365.0
TH3_k127_9488034_7 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 327.0
TH3_k127_9488034_8 membrane K09133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 325.0
TH3_k127_9488034_9 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000003454 248.0
TH3_k127_9500929_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 387.0
TH3_k127_9500929_1 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001509 266.0
TH3_k127_9500929_2 ATP cone domain - - - 0.000000000000000000000000000000000000006366 150.0
TH3_k127_9565178_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K00640,K07062 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000001385 203.0
TH3_k127_9565178_1 RecX family K03565 - - 0.00000000000000000000204 99.0
TH3_k127_9565178_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000007096 93.0
TH3_k127_9565178_3 response to hydrogen peroxide - - - 0.00005906 52.0
TH3_k127_9592770_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 476.0
TH3_k127_9592770_1 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 404.0
TH3_k127_9592770_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000001771 113.0
TH3_k127_970221_0 PFAM peptidase K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 410.0
TH3_k127_970221_1 Mur ligase family, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 312.0
TH3_k127_970221_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000001467 209.0
TH3_k127_970221_3 response regulator receiver - - - 0.00000000000002824 85.0
TH3_k127_9777385_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1546.0
TH3_k127_9777385_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 396.0
TH3_k127_9825321_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 546.0
TH3_k127_9825321_1 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 393.0
TH3_k127_9825321_10 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.0006697 45.0
TH3_k127_9825321_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 314.0
TH3_k127_9825321_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 287.0
TH3_k127_9825321_4 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000000000000000000000000001534 214.0
TH3_k127_9825321_5 Hep Hag repeat protein K01406,K21449 - 3.4.24.40 0.000000000000000000000000000000000000000000002568 180.0
TH3_k127_9825321_6 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000002146 123.0
TH3_k127_9825321_7 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000004635 69.0
TH3_k127_9825321_8 ATP-binding region ATPase domain protein - - - 0.0000002 52.0
TH3_k127_9825321_9 transposase activity K07316,K07495 - 2.1.1.72 0.0000007376 54.0
TH3_k127_9893670_0 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 499.0
TH3_k127_9893670_1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000009328 211.0
TH3_k127_9893670_2 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000004777 207.0
TH3_k127_9893670_3 Peptidase family M23 - - - 0.00000002815 55.0