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Overview

ID MAG03942
Name TH3_bin.3
Sample SMP0102
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family Methanospirillaceae
Genus UBA9949
Species
Assembly information
Completeness (%) 89.94
Contamination (%) 0.01
GC content (%) 53.0
N50 (bp) 13,589
Genome size (bp) 1,508,559

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1607

Gene name Description KEGG GOs EC E-value Score Sequence
TH3_k127_1162020_0 N-6 DNA Methylase - - - 5.119e-226 736.0
TH3_k127_1248347_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 407.0
TH3_k127_1248347_1 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 393.0
TH3_k127_1248347_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000007533 239.0
TH3_k127_1248347_3 - - - - 0.0000000000000000000000000000000000000000000003895 181.0
TH3_k127_1289145_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 516.0
TH3_k127_1289145_1 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 445.0
TH3_k127_1289145_2 CorA-like Mg2+ transporter protein K03284 GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 417.0
TH3_k127_1289145_3 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 389.0
TH3_k127_1289145_4 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 379.0
TH3_k127_1289145_5 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000008315 237.0
TH3_k127_1289145_6 methyltransferase small K07579 - - 0.000000000000000000000000000000000000000000000000000000000000000006832 230.0
TH3_k127_1289145_7 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000007382 217.0
TH3_k127_1289145_8 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000001056 119.0
TH3_k127_1299721_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1848.0
TH3_k127_1299721_1 TIGRFAM UbiD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 592.0
TH3_k127_1299721_10 - - - - 0.0000000000000000000000000000000000003195 144.0
TH3_k127_1299721_11 TIGRFAM methyltransferase FkbM family - - - 0.0000000000000000000000000000005176 123.0
TH3_k127_1299721_12 metallopeptidase activity - - - 0.00000000002788 70.0
TH3_k127_1299721_2 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 540.0
TH3_k127_1299721_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 483.0
TH3_k127_1299721_4 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 381.0
TH3_k127_1299721_5 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005158 255.0
TH3_k127_1299721_6 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000003308 237.0
TH3_k127_1299721_7 Protein of unknown function (DUF432) K09149 - - 0.000000000000000000000000000000000000000000000000000000574 200.0
TH3_k127_1299721_8 PBS lyase K22221 - - 0.0000000000000000000000000000000000000000000000000007538 200.0
TH3_k127_1299721_9 - - - - 0.0000000000000000000000000000000000000003772 155.0
TH3_k127_1314509_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.24e-303 938.0
TH3_k127_1314509_1 Belongs to the dCTP deaminase family K01494,K09887 - 3.5.4.13,3.5.4.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 286.0
TH3_k127_1314509_2 Flavodoxin - - - 0.000000006023 57.0
TH3_k127_1314509_3 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00001306 51.0
TH3_k127_1317976_0 SMART Elongator protein 3 MiaB NifB - - - 4.794e-257 805.0
TH3_k127_1317976_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 3.901e-220 688.0
TH3_k127_1317976_10 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002725 233.0
TH3_k127_1317976_11 Belongs to the UPF0288 family - - - 0.00000000000000000000000000000000000000000000000000000000000000003837 228.0
TH3_k127_1317976_12 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.0000000000000000000000000000000000000000000000000000000000003327 214.0
TH3_k127_1317976_13 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.00000000000000000000000000000000000000000000000000000000004522 208.0
TH3_k127_1317976_14 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000000000000000000001008 166.0
TH3_k127_1317976_15 - - - - 0.000003081 56.0
TH3_k127_1317976_2 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 595.0
TH3_k127_1317976_3 methanogenesis marker protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 488.0
TH3_k127_1317976_4 PFAM elongation factor Tu domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 405.0
TH3_k127_1317976_5 nucleoside 2-deoxyribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 349.0
TH3_k127_1317976_6 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 289.0
TH3_k127_1317976_7 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006405 291.0
TH3_k127_1317976_8 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003969 246.0
TH3_k127_1317976_9 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001845 243.0
TH3_k127_1325975_0 Ferrous iron transport B domain protein K04759 - - 9.884e-228 721.0
TH3_k127_1325975_1 Helix-hairpin-helix domain K02347 - - 2.892e-196 626.0
TH3_k127_1325975_10 - - - - 0.000000007343 68.0
TH3_k127_1325975_11 - - - - 0.0000008931 61.0
TH3_k127_1325975_2 PFAM Radical SAM domain protein K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 398.0
TH3_k127_1325975_3 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 412.0
TH3_k127_1325975_4 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 338.0
TH3_k127_1325975_5 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 330.0
TH3_k127_1325975_6 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000001499 255.0
TH3_k127_1325975_7 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000844 198.0
TH3_k127_1325975_8 iron dependent repressor K03709,K04758 - - 0.00000000000000000000000000000000001061 144.0
TH3_k127_1325975_9 PFAM PKD domain containing protein - - - 0.000000000001548 77.0
TH3_k127_1338270_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 3.262e-225 703.0
TH3_k127_1338270_1 permease K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 380.0
TH3_k127_1338270_10 - - - - 0.000000000000003105 81.0
TH3_k127_1338270_2 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 289.0
TH3_k127_1338270_3 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006577 244.0
TH3_k127_1338270_4 PFAM Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000009161 195.0
TH3_k127_1338270_5 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000000000000000224 188.0
TH3_k127_1338270_6 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000002062 189.0
TH3_k127_1338270_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000001976 109.0
TH3_k127_1338270_8 Nitroreductase - - - 0.000000000000000003447 90.0
TH3_k127_1338270_9 Ammonium Transporter K03320 - - 0.0000000000000001253 81.0
TH3_k127_1375050_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 5.91e-216 688.0
TH3_k127_1375050_1 NADPH-dependent FMN reductase K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 314.0
TH3_k127_1375050_2 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000000000000000000000000000000000000000000000003022 217.0
TH3_k127_1375050_3 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000009088 135.0
TH3_k127_1375050_4 DNA polymerase activity K02319 - 2.7.7.7 0.000000000000000000000000000000009135 135.0
TH3_k127_1375050_6 - - - - 0.000000000006145 67.0
TH3_k127_1375050_7 - - - - 0.0000006494 56.0
TH3_k127_137828_0 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 293.0
TH3_k127_137828_1 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000000000004467 193.0
TH3_k127_137828_2 Fe-S-cluster oxidoreductase - - - 0.00000000000000000000000000000000000000000002961 165.0
TH3_k127_137828_3 - - - - 0.0000000000000001438 86.0
TH3_k127_1408446_0 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 397.0
TH3_k127_1408446_1 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 354.0
TH3_k127_1408446_10 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000000000006383 107.0
TH3_k127_1408446_11 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.000000000000000000000003942 102.0
TH3_k127_1408446_12 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000002156 66.0
TH3_k127_1408446_2 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004269 239.0
TH3_k127_1408446_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000001912 235.0
TH3_k127_1408446_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000000000000001711 224.0
TH3_k127_1408446_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000002156 216.0
TH3_k127_1408446_6 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000000000000000000001275 189.0
TH3_k127_1408446_7 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.00000000000000000000000000000000000000000002068 166.0
TH3_k127_1408446_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000001889 149.0
TH3_k127_1408446_9 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000000000000000000000189 111.0
TH3_k127_1414065_0 CHAD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 390.0
TH3_k127_1414065_1 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001281 230.0
TH3_k127_1414065_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000001495 126.0
TH3_k127_1414065_3 Alpha beta hydrolase fold - - - 0.0000000000000000000123 94.0
TH3_k127_1486980_0 in RNase L inhibitor, RLI K06174 - - 4.197e-307 949.0
TH3_k127_1486980_1 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001068 276.0
TH3_k127_1486980_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000004402 224.0
TH3_k127_1486980_3 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000009344 217.0
TH3_k127_1486980_4 RNase L inhibitor, RLI - - - 0.000000000000000000000000455 108.0
TH3_k127_151887_0 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 346.0
TH3_k127_151887_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004162 241.0
TH3_k127_151887_2 PFAM Amidohydrolase 2 K07045 - - 0.000000000000000000000000002089 115.0
TH3_k127_1520115_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 1.912e-291 901.0
TH3_k127_1520115_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 605.0
TH3_k127_1520115_10 Uncharacterized protein, homolog of nitrogen regulatory protein PII - - - 0.000000000000000000000000000000000000000000000000002175 184.0
TH3_k127_1520115_11 COG1174 ABC-type proline glycine betaine transport systems, permease component K05846 - - 0.000000000000000000000000000000000000000000000002688 182.0
TH3_k127_1520115_12 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171,K00188 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000004595 139.0
TH3_k127_1520115_13 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000005398 121.0
TH3_k127_1520115_14 DNA modification - - - 0.0000000003022 63.0
TH3_k127_1520115_2 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 548.0
TH3_k127_1520115_3 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 462.0
TH3_k127_1520115_4 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 409.0
TH3_k127_1520115_5 CBS domain K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 361.0
TH3_k127_1520115_6 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003558 282.0
TH3_k127_1520115_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000005305 247.0
TH3_k127_1520115_8 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000005329 226.0
TH3_k127_1520115_9 COG1174 ABC-type proline glycine betaine transport systems, permease component K05846 - - 0.000000000000000000000000000000000000000000000000000000001556 207.0
TH3_k127_1584343_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 449.0
TH3_k127_1584343_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 366.0
TH3_k127_1584343_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 328.0
TH3_k127_1584343_3 PHP-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 314.0
TH3_k127_1584343_4 PFAM TspO MBR family K05770 - - 0.0000000000000000000000000000000000000000000004217 171.0
TH3_k127_1668343_0 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 381.0
TH3_k127_1668343_1 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000000000000000000000000000000000000004983 227.0
TH3_k127_1668343_2 UbiA prenyltransferase family - - - 0.00000000000000000000000000004671 128.0
TH3_k127_1739921_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 596.0
TH3_k127_1739921_1 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 567.0
TH3_k127_1739921_10 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000002106 76.0
TH3_k127_1739921_2 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 536.0
TH3_k127_1739921_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 427.0
TH3_k127_1739921_4 Belongs to the UPF0285 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 408.0
TH3_k127_1739921_5 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 282.0
TH3_k127_1739921_6 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000002206 192.0
TH3_k127_1739921_7 Putative small multi-drug export protein - - - 0.0000000000000000000000000000001463 128.0
TH3_k127_1739921_8 Peptidyl-prolyl cis-trans K01802,K03768,K03775 - 5.2.1.8 0.0000000000000000000000000000002053 128.0
TH3_k127_1739921_9 helicase activity K06915 - - 0.000000000000000000000000001354 119.0
TH3_k127_1768538_0 2Fe-2S iron-sulfur cluster binding domain - - - 4.55e-289 899.0
TH3_k127_1768538_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 1.411e-283 878.0
TH3_k127_1768538_10 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 314.0
TH3_k127_1768538_11 PFAM TM2 domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 297.0
TH3_k127_1768538_12 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004103 296.0
TH3_k127_1768538_13 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000005314 256.0
TH3_k127_1768538_14 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000000406 213.0
TH3_k127_1768538_15 PFAM TM2 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000005675 205.0
TH3_k127_1768538_16 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000957 179.0
TH3_k127_1768538_17 RimK domain protein ATP-grasp K05844,K15740 - 6.3.2.33 0.000000000000000000000000000000000009509 141.0
TH3_k127_1768538_18 - - - - 0.0000000000000000000021 96.0
TH3_k127_1768538_19 bacterial-type flagellum-dependent cell motility - - - 0.0000000003446 69.0
TH3_k127_1768538_2 Uncharacterized protein conserved in archaea (DUF2114) - - - 6.017e-261 811.0
TH3_k127_1768538_20 bacterial-type flagellum-dependent cell motility - - - 0.000000001529 69.0
TH3_k127_1768538_21 - - - - 0.00001183 59.0
TH3_k127_1768538_3 PFAM Radical SAM domain protein K06937 - - 1.959e-247 770.0
TH3_k127_1768538_4 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 603.0
TH3_k127_1768538_5 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 586.0
TH3_k127_1768538_6 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 428.0
TH3_k127_1768538_7 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 428.0
TH3_k127_1768538_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 428.0
TH3_k127_1768538_9 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 372.0
TH3_k127_1908631_0 PFAM AMP-dependent synthetase and ligase K00666 - - 1.548e-312 967.0
TH3_k127_1908631_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.191e-283 887.0
TH3_k127_1908631_10 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002635 254.0
TH3_k127_1908631_11 Crossover junction endodeoxyribonuclease RuvC K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000006832 186.0
TH3_k127_1908631_12 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000003227 178.0
TH3_k127_1908631_13 RuvA, C-terminal domain K03550 - 3.6.4.12 0.000000000000000000000000000000000000000001629 163.0
TH3_k127_1908631_14 - K02478 - 2.7.13.3 0.000000000000000002259 86.0
TH3_k127_1908631_15 - - - - 0.00000000000000002816 86.0
TH3_k127_1908631_16 - - - - 0.000000000000000422 83.0
TH3_k127_1908631_17 - K02478 - 2.7.13.3 0.000000000000004112 77.0
TH3_k127_1908631_18 - K02478 - 2.7.13.3 0.000000000000005006 78.0
TH3_k127_1908631_19 defense response to virus K07061 - - 0.0000000000003067 76.0
TH3_k127_1908631_2 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 1.998e-201 632.0
TH3_k127_1908631_20 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000009392 61.0
TH3_k127_1908631_21 - K06193 - - 0.000000004119 58.0
TH3_k127_1908631_22 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.0002798 43.0
TH3_k127_1908631_3 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 572.0
TH3_k127_1908631_4 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 511.0
TH3_k127_1908631_5 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 494.0
TH3_k127_1908631_6 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 483.0
TH3_k127_1908631_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 290.0
TH3_k127_1908631_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005046 280.0
TH3_k127_1908631_9 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004014 272.0
TH3_k127_1997308_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.342e-264 822.0
TH3_k127_1997308_1 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 9.552e-200 627.0
TH3_k127_1997308_10 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000399 195.0
TH3_k127_1997308_11 - - - - 0.0000000000000000000000000000000000000001486 157.0
TH3_k127_1997308_12 DGC domain - - - 0.0000000000000000000000000000000000002278 148.0
TH3_k127_1997308_13 DGC domain - - - 0.000000000000000000000000000000000006029 140.0
TH3_k127_1997308_14 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.0000000000000000000000000000001259 129.0
TH3_k127_1997308_15 PFAM regulatory protein, ArsR K21903 - - 0.000000000000000000000000000004026 126.0
TH3_k127_1997308_16 - - - - 0.00000000000000000000000006723 109.0
TH3_k127_1997308_17 DGC domain - - - 0.00000000000000001189 91.0
TH3_k127_1997308_2 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 479.0
TH3_k127_1997308_3 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 473.0
TH3_k127_1997308_4 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 405.0
TH3_k127_1997308_5 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 396.0
TH3_k127_1997308_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001676 284.0
TH3_k127_1997308_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001147 276.0
TH3_k127_1997308_8 pyrroline-5-carboxylate reductase activity K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007527 274.0
TH3_k127_1997308_9 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000001486 222.0
TH3_k127_217901_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.4e-259 801.0
TH3_k127_217901_1 Involved in cell shape control K22222 - - 4.07e-200 629.0
TH3_k127_217901_10 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 263.0
TH3_k127_217901_11 PFAM Phosphatidylglycerophosphatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000481 228.0
TH3_k127_217901_12 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000000000009405 204.0
TH3_k127_217901_13 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000001608 183.0
TH3_k127_217901_14 - - - - 0.0000000000000000000000000000000000000000000002363 181.0
TH3_k127_217901_15 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000006978 165.0
TH3_k127_217901_16 - - - - 0.0000000000000000000000446 103.0
TH3_k127_217901_2 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 587.0
TH3_k127_217901_3 TIGRFAM TraB family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 511.0
TH3_k127_217901_4 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 504.0
TH3_k127_217901_5 Belongs to the UPF0284 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 439.0
TH3_k127_217901_6 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009894 408.0
TH3_k127_217901_7 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 377.0
TH3_k127_217901_8 PFAM Glycosyl transferase family 2 K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 314.0
TH3_k127_217901_9 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001535 263.0
TH3_k127_224605_0 COG0784 FOG CheY-like receiver K01584 - 4.1.1.19 0.0 1163.0
TH3_k127_224605_1 PFAM amino acid permease-associated region K20265 - - 1.38e-226 710.0
TH3_k127_224605_10 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 352.0
TH3_k127_224605_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 306.0
TH3_k127_224605_12 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001913 259.0
TH3_k127_224605_13 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000005224 244.0
TH3_k127_224605_14 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000002616 189.0
TH3_k127_224605_15 PFAM Methyltransferase type - - - 0.000000000000000000000000000000000000000000002931 166.0
TH3_k127_224605_16 - - - - 0.000000000000000000000000002244 117.0
TH3_k127_224605_2 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 2.123e-207 656.0
TH3_k127_224605_3 PFAM PUA domain containing protein K07557 - 2.6.1.97 1.9e-205 652.0
TH3_k127_224605_4 PFAM peptidase U32 K08303 - - 3.501e-202 659.0
TH3_k127_224605_5 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.238e-199 631.0
TH3_k127_224605_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 470.0
TH3_k127_224605_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 458.0
TH3_k127_224605_8 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 456.0
TH3_k127_224605_9 Sulfide dehydrogenase (Flavoprotein) subunit SudB K00528,K02823 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 389.0
TH3_k127_2283384_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 332.0
TH3_k127_2283384_1 - - - - 0.0000000000000000000000000000000000239 140.0
TH3_k127_2283384_2 PFAM TPR repeat-containing protein - - - 0.000000000000000008087 87.0
TH3_k127_2283384_3 PFAM TPR repeat-containing protein - - - 0.0000000000000006551 82.0
TH3_k127_2311644_0 PFAM dihydropteroate synthase, DHPS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 489.0
TH3_k127_2311644_1 Prokaryotic homologs of the JAB domain - - - 0.00000000000000000000000000000000000000000000000000000000005183 212.0
TH3_k127_2311644_2 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.0000000000000000000000000000002309 123.0
TH3_k127_2330437_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 456.0
TH3_k127_2330437_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 417.0
TH3_k127_2330437_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 362.0
TH3_k127_2330437_3 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 335.0
TH3_k127_2330437_4 PFAM transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000001518 215.0
TH3_k127_2330437_5 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000000002362 162.0
TH3_k127_2330437_6 Protein of unknown function DUF47 K07220 - - 0.00003588 48.0
TH3_k127_2531771_0 Protein of unknown function (DUF460) K09150 - - 3.712e-257 807.0
TH3_k127_2531771_1 PFAM TrkA-N domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 516.0
TH3_k127_2531771_2 PFAM PP-loop domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 387.0
TH3_k127_2531771_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 349.0
TH3_k127_2531771_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 313.0
TH3_k127_2531771_5 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000006222 261.0
TH3_k127_2531771_6 RIO-like serine threonine protein kinase fused to N-terminal HTH domain K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000002329 227.0
TH3_k127_2605940_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.0 1339.0
TH3_k127_2605940_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 1.731e-228 717.0
TH3_k127_2605940_10 archaeosine synthase activity K07557 - 2.6.1.97 0.00000000003128 64.0
TH3_k127_2605940_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 439.0
TH3_k127_2605940_3 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 359.0
TH3_k127_2605940_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 353.0
TH3_k127_2605940_5 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 329.0
TH3_k127_2605940_6 PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 305.0
TH3_k127_2605940_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000005336 260.0
TH3_k127_2605940_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000003004 156.0
TH3_k127_2605940_9 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000000000000000001979 111.0
TH3_k127_2680994_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 2.892e-260 814.0
TH3_k127_2680994_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 6.561e-215 676.0
TH3_k127_2680994_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 295.0
TH3_k127_2680994_3 NTPase - - - 0.000000000000000000000000000000000000000000006934 168.0
TH3_k127_2680994_4 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000001199 123.0
TH3_k127_272769_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1133.0
TH3_k127_272769_1 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00125 - 1.17.1.9 1.039e-224 700.0
TH3_k127_272769_10 - - - - 0.00000000000000004277 88.0
TH3_k127_272769_11 Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits K14572 - - 0.000002748 62.0
TH3_k127_272769_12 protein with SCP PR1 domains - - - 0.00004389 46.0
TH3_k127_272769_2 ATP-grasp domain K06914 - 6.3.4.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 413.0
TH3_k127_272769_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 407.0
TH3_k127_272769_4 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 368.0
TH3_k127_272769_5 COG1361 S-layer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 372.0
TH3_k127_272769_6 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 335.0
TH3_k127_272769_7 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003921 274.0
TH3_k127_272769_8 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000000000000000000003619 173.0
TH3_k127_272769_9 - - - - 0.0000000000000000000000000000000000000000001909 164.0
TH3_k127_2744046_0 COG0433 Predicted ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002586 274.0
TH3_k127_2744046_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000008359 217.0
TH3_k127_2744046_2 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000004294 172.0
TH3_k127_2795010_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0 1036.0
TH3_k127_2795010_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 5.55e-274 846.0
TH3_k127_2795010_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000000000000000000000000000000000000002228 221.0
TH3_k127_2795010_11 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000001227 179.0
TH3_k127_2795010_12 - - - - 0.0000000000000000000000000000000000000000002306 164.0
TH3_k127_2795010_13 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 0.0000000000000000000000000000000000000001475 154.0
TH3_k127_2795010_14 - - - - 0.0000000000000000000000000000000005805 134.0
TH3_k127_2795010_15 Glutaredoxin - - - 0.0000000000000000000000000000000009364 132.0
TH3_k127_2795010_16 - - - - 0.000000000000000000000000000000006323 130.0
TH3_k127_2795010_17 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000000000000003317 109.0
TH3_k127_2795010_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000003314 96.0
TH3_k127_2795010_19 - - - - 0.0000000000000003049 85.0
TH3_k127_2795010_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 7.648e-225 715.0
TH3_k127_2795010_3 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 615.0
TH3_k127_2795010_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 586.0
TH3_k127_2795010_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 436.0
TH3_k127_2795010_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 327.0
TH3_k127_2795010_7 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001528 280.0
TH3_k127_2795010_8 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000001016 235.0
TH3_k127_2795010_9 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000000000000000005104 229.0
TH3_k127_2843150_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 432.0
TH3_k127_2843150_1 Domain of unknown function (DUF1848) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 372.0
TH3_k127_2843150_2 Domain of unknown function (DUF3821) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 341.0
TH3_k127_2843150_4 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.000000000000001359 78.0
TH3_k127_2917792_0 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 464.0
TH3_k127_2917792_1 Belongs to the 'phage' integrase family - - - 0.0002916 46.0
TH3_k127_2919686_0 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 287.0
TH3_k127_2919686_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000002302 127.0
TH3_k127_2919686_2 IMG reference gene - - - 0.000000007143 62.0
TH3_k127_297735_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.145e-295 916.0
TH3_k127_297735_1 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 1.314e-285 885.0
TH3_k127_297735_10 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaH K14099 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001681 274.0
TH3_k127_297735_11 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009982 256.0
TH3_k127_297735_12 amino acid K16263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003701 264.0
TH3_k127_297735_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14107 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001165 247.0
TH3_k127_297735_14 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000468 207.0
TH3_k127_297735_15 Predicted membrane protein (DUF2105) K14098 - - 0.00000000000000000000000000000000000000000000000000000000006258 210.0
TH3_k127_297735_16 PFAM ribosomal protein S8E K02995 - - 0.0000000000000000000000000000000000000000000000000000001609 196.0
TH3_k127_297735_17 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000939 196.0
TH3_k127_297735_18 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaF K14097 - - 0.0000000000000000000000000000000000000000000000000005191 188.0
TH3_k127_297735_19 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.000000000000000000000000000000000000000000000000003153 186.0
TH3_k127_297735_2 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 1.147e-214 673.0
TH3_k127_297735_20 - - - - 0.00000000000000000000000000000000000000000000136 176.0
TH3_k127_297735_21 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.0000000000000000000000000000000000000000005815 162.0
TH3_k127_297735_22 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.00000000000000000000000000558 112.0
TH3_k127_297735_23 Predicted membrane protein (DUF2109) K14094 - - 0.0000000000000000000000000141 110.0
TH3_k127_297735_24 - - - - 0.0000000000000000000000002097 105.0
TH3_k127_297735_25 PFAM NiFe -hydrogenase-3-type complex Eha, EhaM K14104 - - 0.0000000000000000000003502 101.0
TH3_k127_297735_26 PFAM molydopterin dinucleotide-binding region K00203 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.2.7.12 0.000000000000000000001685 98.0
TH3_k127_297735_27 RNA-binding protein involved in rRNA processing K07569 - - 0.0000000000000000000253 93.0
TH3_k127_297735_28 Predicted membrane protein (DUF2108) K14095 - - 0.000000000009821 70.0
TH3_k127_297735_29 - - - - 0.0000006709 55.0
TH3_k127_297735_3 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 3.115e-204 638.0
TH3_k127_297735_30 - K14100 - - 0.000001032 53.0
TH3_k127_297735_31 - - - - 0.00004131 49.0
TH3_k127_297735_32 4Fe-4S binding domain K03616 - - 0.0005491 44.0
TH3_k127_297735_4 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 553.0
TH3_k127_297735_5 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 370.0
TH3_k127_297735_6 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 374.0
TH3_k127_297735_7 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 353.0
TH3_k127_297735_8 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 304.0
TH3_k127_297735_9 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 300.0
TH3_k127_3040219_0 transcriptional regulator, ArsR family K07013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004 246.0
TH3_k127_3040219_1 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000000000000001075 140.0
TH3_k127_3040219_2 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.0000000000000000005663 87.0
TH3_k127_3040219_3 Protein of unknown function (DUF1059) - - - 0.0000004685 54.0
TH3_k127_3043452_0 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 486.0
TH3_k127_3043452_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 450.0
TH3_k127_3043452_2 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 370.0
TH3_k127_3043452_3 - - - - 0.000000000000000000000000000000007636 130.0
TH3_k127_3084157_0 PFAM ABC transporter K00400 - - 4.219e-280 867.0
TH3_k127_3084157_1 Belongs to the UPF0288 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 400.0
TH3_k127_3104930_0 extracellular matrix structural constituent K01385 - 3.4.23.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 431.0
TH3_k127_3104930_1 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 333.0
TH3_k127_3104930_2 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00125 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001649 252.0
TH3_k127_3204158_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.0 1031.0
TH3_k127_3204158_1 COG0477 Permeases of the major facilitator superfamily K08177 - - 7.297e-200 629.0
TH3_k127_3204158_10 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000001586 201.0
TH3_k127_3204158_11 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007,K02009 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000002906 139.0
TH3_k127_3204158_12 chorismate mutase K04093 - 5.4.99.5 0.00000000000000000000000009389 110.0
TH3_k127_3204158_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 537.0
TH3_k127_3204158_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 526.0
TH3_k127_3204158_4 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 514.0
TH3_k127_3204158_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 428.0
TH3_k127_3204158_6 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 376.0
TH3_k127_3204158_7 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 357.0
TH3_k127_3204158_8 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008929 277.0
TH3_k127_3204158_9 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000028 250.0
TH3_k127_3234474_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001787 286.0
TH3_k127_3234474_1 - - - - 0.0000000000000000000000002981 108.0
TH3_k127_3234474_2 Ferric reductase like transmembrane component - - - 0.000000000000000002267 91.0
TH3_k127_3234474_3 TIR domain - - - 0.0000000114 63.0
TH3_k127_329734_0 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 586.0
TH3_k127_329734_1 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 467.0
TH3_k127_329734_2 PFAM metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 336.0
TH3_k127_329734_3 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 297.0
TH3_k127_329734_4 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.000000000000000000000000000000000000000000000000000000000008266 207.0
TH3_k127_329734_5 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000003498 198.0
TH3_k127_329734_6 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000000000000000000000557 196.0
TH3_k127_329734_7 TIR domain - - - 0.0000000000000002135 85.0
TH3_k127_342085_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 8.749e-261 817.0
TH3_k127_342085_1 Predicted membrane protein (DUF2070) K08979 - - 1.231e-206 657.0
TH3_k127_342085_10 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 447.0
TH3_k127_342085_11 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 439.0
TH3_k127_342085_12 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 408.0
TH3_k127_342085_13 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 389.0
TH3_k127_342085_14 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 378.0
TH3_k127_342085_15 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 373.0
TH3_k127_342085_16 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 370.0
TH3_k127_342085_17 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 321.0
TH3_k127_342085_18 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 283.0
TH3_k127_342085_19 Oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 282.0
TH3_k127_342085_2 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 5.515e-194 611.0
TH3_k127_342085_20 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 284.0
TH3_k127_342085_21 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004273 270.0
TH3_k127_342085_22 methanogen marker protein 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009967 265.0
TH3_k127_342085_23 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001164 270.0
TH3_k127_342085_24 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001094 252.0
TH3_k127_342085_25 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003436 239.0
TH3_k127_342085_26 Pas domain - - - 0.0000000000000000000000000000000000000000000000000000000005126 226.0
TH3_k127_342085_27 Belongs to the UPF0212 family K09731 - - 0.000000000000000000000000000000000000000000000000000001449 193.0
TH3_k127_342085_28 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000003455 187.0
TH3_k127_342085_29 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000000000000000000000000000000007871 163.0
TH3_k127_342085_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 562.0
TH3_k127_342085_30 Thioesterase superfamily K02614 - - 0.000000000000000000000000000000004007 130.0
TH3_k127_342085_31 secretion by the type IV secretion system K07332 - - 0.00000000000000000000000000001741 128.0
TH3_k127_342085_32 transcription factor (CBF NF-Y) - - - 0.000000000000000000000000001202 112.0
TH3_k127_342085_33 Family of unknown function (DUF5350) - - - 0.0000000000000000000000003741 108.0
TH3_k127_342085_34 Pas domain - - - 0.0000000000000000000000009709 110.0
TH3_k127_342085_35 - - - - 0.0000000000000000000001867 100.0
TH3_k127_342085_36 PFAM TPR repeat-containing protein - - - 0.000000000000000000001012 99.0
TH3_k127_342085_37 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000006745 57.0
TH3_k127_342085_4 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 572.0
TH3_k127_342085_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 542.0
TH3_k127_342085_6 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 518.0
TH3_k127_342085_7 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 507.0
TH3_k127_342085_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 508.0
TH3_k127_342085_9 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 472.0
TH3_k127_342507_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.597e-226 709.0
TH3_k127_342507_1 Protein-export membrane protein SecD K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 600.0
TH3_k127_342507_2 Involved in protein export K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 374.0
TH3_k127_342507_3 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 301.0
TH3_k127_342507_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000001834 216.0
TH3_k127_342507_5 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000002302 208.0
TH3_k127_342507_6 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000001314 147.0
TH3_k127_342507_7 PFAM Thioredoxin K03671 - - 0.000000000000000000000000000000000001777 140.0
TH3_k127_342507_8 Protein of unknown function (DUF2551) - - - 0.0000000000000000000000000000001785 125.0
TH3_k127_342507_9 - - - - 0.0000000000000000000000001899 108.0
TH3_k127_3436536_0 PFAM phosphoesterase, RecJ domain protein K07463 - - 5.652e-195 618.0
TH3_k127_3436536_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 378.0
TH3_k127_3436536_2 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 330.0
TH3_k127_3436536_3 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000000000000000001509 150.0
TH3_k127_3436536_4 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000007555 72.0
TH3_k127_3442889_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 3.736e-212 669.0
TH3_k127_3442889_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 541.0
TH3_k127_3442889_2 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 478.0
TH3_k127_3442889_3 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 331.0
TH3_k127_3442889_4 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000732 278.0
TH3_k127_3442889_5 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000003906 236.0
TH3_k127_3442889_6 SMART Excinuclease ABC, C subunit - - - 0.00000000000000000000000000000000000004474 148.0
TH3_k127_3442889_7 Domain of unknown function (DUF1805) - - - 0.000000000000000000000001775 110.0
TH3_k127_3442889_8 beta-lactamase domain protein - - - 0.00003522 46.0
TH3_k127_353430_0 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 584.0
TH3_k127_353430_1 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 535.0
TH3_k127_353430_10 - K06868 - 2.5.1.73 0.00000000000001087 75.0
TH3_k127_353430_11 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000003778 56.0
TH3_k127_353430_2 PFAM formate nitrite transporter K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 455.0
TH3_k127_353430_3 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 450.0
TH3_k127_353430_4 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 372.0
TH3_k127_353430_5 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 333.0
TH3_k127_353430_6 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 325.0
TH3_k127_353430_7 PFAM Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000006536 199.0
TH3_k127_353430_8 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.0000000000000000000000000000000000000000000000000006161 194.0
TH3_k127_353430_9 COG1881 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000006773 173.0
TH3_k127_3562274_0 PFAM ribonuclease II K01147 - 3.1.13.1 8.881e-219 689.0
TH3_k127_3562274_1 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 394.0
TH3_k127_3562274_2 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 298.0
TH3_k127_3562274_3 SMART zinc finger, CDGSH-type domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007687 272.0
TH3_k127_3562274_4 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000000000000000001753 218.0
TH3_k127_3562274_5 - - - - 0.000000000000000000001903 101.0
TH3_k127_3562274_6 - - - - 0.0000000000000005025 81.0
TH3_k127_3562274_8 tetratricopeptide repeat - - - 0.00000002863 58.0
TH3_k127_35911_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 1.097e-255 798.0
TH3_k127_35911_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 1.566e-233 729.0
TH3_k127_35911_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 2.41e-213 670.0
TH3_k127_35911_3 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 467.0
TH3_k127_35911_4 ZPR1-related zinc finger protein K06874 - - 0.000000000000000000000000000000000000000000000000000000000000435 215.0
TH3_k127_35911_5 Pfam:DUF552 K09152 - - 0.00000000000000000000000000000000000000000000000000000345 192.0
TH3_k127_3635824_0 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0 1080.0
TH3_k127_3635824_1 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000004454 109.0
TH3_k127_3640149_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 580.0
TH3_k127_3640149_1 DEAD DEAH box helicase domain protein K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 544.0
TH3_k127_3640149_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 471.0
TH3_k127_3640149_4 - K00960 - 2.7.7.6 0.0000000000000000000000003727 104.0
TH3_k127_3640149_5 Protein of unknown function (DUF2769) - - - 0.0000000000000000002604 92.0
TH3_k127_365006_0 PFAM type II secretion system protein E K07332 - - 7.863e-281 875.0
TH3_k127_365006_1 Type II secretion system (T2SS), protein F K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 352.0
TH3_k127_365006_2 Type II secretion system (T2SS), protein F K07333 - - 0.0000000000000000000000884 106.0
TH3_k127_3650589_0 AMP-binding enzyme - - - 1.214e-207 653.0
TH3_k127_3650589_1 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 372.0
TH3_k127_3650589_2 Integral membrane protein DUF106 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001064 241.0
TH3_k127_3650589_3 UPF0056 membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000001447 241.0
TH3_k127_3650589_4 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000225 223.0
TH3_k127_3650589_5 COG2041 Sulfite oxidase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000003198 217.0
TH3_k127_3650589_6 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000001026 177.0
TH3_k127_3689334_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 4.805e-200 633.0
TH3_k127_3689334_1 PFAM PKD domain containing protein - - - 0.000000000000000000299 95.0
TH3_k127_3689334_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0001739 50.0
TH3_k127_3803210_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.182e-262 812.0
TH3_k127_3803210_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 572.0
TH3_k127_3803210_10 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007171 270.0
TH3_k127_3803210_11 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000008697 251.0
TH3_k127_3803210_12 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000004734 239.0
TH3_k127_3803210_13 RibD C-terminal domain K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000005664 209.0
TH3_k127_3803210_14 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000000000000005846 165.0
TH3_k127_3803210_15 integral membrane protein - - - 0.000000000000000000000000000000000001439 147.0
TH3_k127_3803210_16 Belongs to the TrpF family K01696,K01817 - 4.2.1.20,5.3.1.24 0.0000000000000000000000000000004215 129.0
TH3_k127_3803210_17 Uracil DNA glycosylase superfamily K03649 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097507,GO:0140097,GO:1901360 3.2.2.28 0.000000000000000000000000001519 118.0
TH3_k127_3803210_18 Transcriptional regulator K07729 - - 0.00000000000000000000000007349 109.0
TH3_k127_3803210_19 - - - - 0.0000000000000000000004997 100.0
TH3_k127_3803210_2 Radical SAM ThiC family K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 467.0
TH3_k127_3803210_20 - - - - 0.000000000000002946 84.0
TH3_k127_3803210_21 Psort location Cytoplasmic, score - - - 0.0000259 53.0
TH3_k127_3803210_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 462.0
TH3_k127_3803210_4 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 387.0
TH3_k127_3803210_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 376.0
TH3_k127_3803210_6 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000303 284.0
TH3_k127_3803210_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009002 277.0
TH3_k127_3803210_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005732 274.0
TH3_k127_3803210_9 PFAM nucleoside recognition domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001476 276.0
TH3_k127_3822106_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 2.649e-245 767.0
TH3_k127_3822106_1 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 5.039e-245 766.0
TH3_k127_3822106_10 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000007237 190.0
TH3_k127_3822106_11 Sodium hydrogen exchanger K03455 - - 0.000000000000000000245 91.0
TH3_k127_3822106_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 1.386e-225 704.0
TH3_k127_3822106_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 397.0
TH3_k127_3822106_4 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 396.0
TH3_k127_3822106_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 328.0
TH3_k127_3822106_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001331 282.0
TH3_k127_3822106_7 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003374 275.0
TH3_k127_3822106_8 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.0000000000000000000000000000000000000000000000000000000000001058 214.0
TH3_k127_3822106_9 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
TH3_k127_3822587_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.039e-208 653.0
TH3_k127_3822587_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 480.0
TH3_k127_3822587_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 394.0
TH3_k127_3822587_3 TIGRFAM F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 314.0
TH3_k127_3822587_4 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001802 280.0
TH3_k127_3822587_5 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000000000000000000000000000000000000000000000000000000005111 241.0
TH3_k127_3822587_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001074 217.0
TH3_k127_3822587_7 - - - - 0.00000000000000000000002021 107.0
TH3_k127_3859087_0 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 1.522e-240 751.0
TH3_k127_3859087_1 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 537.0
TH3_k127_3859087_2 Protein of unknown function (DUF4013) - - - 0.0000000000000000000000000000000000000000000000000000000000002048 219.0
TH3_k127_3859087_3 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.00000000000000000000000000000000008819 133.0
TH3_k127_3923518_0 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 587.0
TH3_k127_3923518_1 PFAM Archaeal protein of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 482.0
TH3_k127_3923518_2 - K14093 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003291 240.0
TH3_k127_3923518_3 - K00960 - 2.7.7.6 0.0000000000000000000000000006552 112.0
TH3_k127_3923518_4 Predicted membrane protein (DUF2109) K14094 - - 0.00000000000000000000000003634 112.0
TH3_k127_3923518_5 Predicted membrane protein (DUF2108) K14095 - - 0.00000000001843 69.0
TH3_k127_3923518_6 Predicted membrane protein (DUF2107) K14096 - - 0.0007427 42.0
TH3_k127_3925688_0 - K08963 - 5.3.1.23 1.969e-214 671.0
TH3_k127_3925688_1 Met-10+ like-protein K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000001444 259.0
TH3_k127_3925688_2 - - - - 0.0000000000000000000000306 106.0
TH3_k127_3925688_3 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000004911 102.0
TH3_k127_3925688_4 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000000000000000000005775 106.0
TH3_k127_3925688_5 permease - - - 0.0000000000000000002863 99.0
TH3_k127_3925688_6 small multi-drug export - - - 0.000000000000000001864 92.0
TH3_k127_3977178_0 Belongs to the glutamate synthase family - - - 5.506e-271 839.0
TH3_k127_3977178_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 6.55e-232 724.0
TH3_k127_3977178_2 PFAM glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 553.0
TH3_k127_4005775_0 CBS domain containing protein K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 493.0
TH3_k127_4005775_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002726 265.0
TH3_k127_402954_0 PFAM Beta propeller domain K14475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 616.0
TH3_k127_402954_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 592.0
TH3_k127_402954_10 COGs COG0515 Serine threonine protein kinase - - - 0.00007011 54.0
TH3_k127_402954_2 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 573.0
TH3_k127_402954_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 496.0
TH3_k127_402954_4 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 401.0
TH3_k127_402954_5 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 332.0
TH3_k127_402954_6 Dihydrouridine synthase (Dus) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 318.0
TH3_k127_402954_7 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.000000000000000000000000000000000000000000000000000001496 194.0
TH3_k127_402954_8 CBS domain - - - 0.00000000000000000000000000000079 133.0
TH3_k127_402954_9 - - - - 0.0000000000002048 71.0
TH3_k127_4031502_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 2.219e-297 919.0
TH3_k127_4031502_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 2.466e-257 799.0
TH3_k127_4031502_10 Domain of unknown function (DUF1743) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 419.0
TH3_k127_4031502_11 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 389.0
TH3_k127_4031502_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 362.0
TH3_k127_4031502_13 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 363.0
TH3_k127_4031502_14 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 361.0
TH3_k127_4031502_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 351.0
TH3_k127_4031502_16 unfolded protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 317.0
TH3_k127_4031502_17 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 296.0
TH3_k127_4031502_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01657,K02500 GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 292.0
TH3_k127_4031502_19 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 299.0
TH3_k127_4031502_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 2.254e-241 749.0
TH3_k127_4031502_20 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000005926 216.0
TH3_k127_4031502_21 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04068 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000009919 196.0
TH3_k127_4031502_22 WD-40 repeat protein - - - 0.0000000000000000000000000000000000000000000003883 192.0
TH3_k127_4031502_23 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11260 - - 0.000000000000000000000000000000000000001978 148.0
TH3_k127_4031502_24 - - - - 0.0000000000000000000000000000000003531 134.0
TH3_k127_4031502_25 PFAM Uncharacterised protein family Ycf35 - - - 0.000000000000000001358 90.0
TH3_k127_4031502_26 Peptidyl-prolyl cis-trans K01802,K03768,K03775 - 5.2.1.8 0.00000000000222 70.0
TH3_k127_4031502_27 - - - - 0.0000000002521 63.0
TH3_k127_4031502_28 - - - - 0.000000006662 64.0
TH3_k127_4031502_29 Protein of unknown function (DUF2997) - - - 0.00002848 49.0
TH3_k127_4031502_3 ATPase family associated with various cellular activities (AAA) - - - 5.133e-235 737.0
TH3_k127_4031502_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.124e-197 622.0
TH3_k127_4031502_5 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 555.0
TH3_k127_4031502_6 PFAM Radical SAM domain protein K02585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 549.0
TH3_k127_4031502_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 542.0
TH3_k127_4031502_8 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 518.0
TH3_k127_4031502_9 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 432.0
TH3_k127_4069903_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 417.0
TH3_k127_4069903_1 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 328.0
TH3_k127_4069903_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 301.0
TH3_k127_4069903_3 - - - - 0.00002338 53.0
TH3_k127_4191904_0 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 2.254e-204 638.0
TH3_k127_4191904_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 318.0
TH3_k127_4191904_2 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000007696 220.0
TH3_k127_4191904_3 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000001584 107.0
TH3_k127_4260875_0 PFAM Thiolase K00626 - 2.3.1.9 5.143e-211 661.0
TH3_k127_4260875_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 593.0
TH3_k127_4260875_10 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 304.0
TH3_k127_4260875_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 290.0
TH3_k127_4260875_12 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 284.0
TH3_k127_4260875_13 Helix-turn-helix domain protein K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000003367 241.0
TH3_k127_4260875_14 Anaerobic ribonucleoside-triphosphate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001847 226.0
TH3_k127_4260875_15 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000000000000009049 217.0
TH3_k127_4260875_16 COG1246 N-acetylglutamate synthase and related acetyltransferases K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000102 218.0
TH3_k127_4260875_17 zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000003472 214.0
TH3_k127_4260875_18 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000006711 199.0
TH3_k127_4260875_19 Domain of unknown function (DUF1858) - - - 0.00000000000000000000000008603 107.0
TH3_k127_4260875_2 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 588.0
TH3_k127_4260875_20 Ribonuclease K03469 - 3.1.26.4 0.0000000000000000000000002084 114.0
TH3_k127_4260875_21 Ferredoxin K05337 - - 0.00000000000000002917 83.0
TH3_k127_4260875_22 - - - - 0.0000000000000004877 81.0
TH3_k127_4260875_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 540.0
TH3_k127_4260875_4 Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 504.0
TH3_k127_4260875_5 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 467.0
TH3_k127_4260875_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 459.0
TH3_k127_4260875_7 Methyltransferase K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 357.0
TH3_k127_4260875_8 Cysteine-rich small domain K08260 - 3.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 357.0
TH3_k127_4260875_9 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 348.0
TH3_k127_4369784_0 AAA-like domain K06915 - - 4.693e-223 704.0
TH3_k127_4369784_1 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
TH3_k127_4369784_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001509 267.0
TH3_k127_4369784_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000001004 78.0
TH3_k127_4399038_0 PFAM Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000002484 229.0
TH3_k127_4399038_1 Proline dehydrogenase K00318 - - 0.00000000000000000006986 100.0
TH3_k127_4399038_2 - - - - 0.00000001359 60.0
TH3_k127_4399038_3 Flavodoxin - - - 0.0002416 44.0
TH3_k127_4510743_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 474.0
TH3_k127_4510743_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 460.0
TH3_k127_4510743_10 CBS domain - - - 0.0000000000000000000000000000000002546 136.0
TH3_k127_4510743_11 Nitroreductase - - - 0.000000000000000000000000001081 123.0
TH3_k127_4510743_12 transcriptional regulators K03724 - - 0.0000000000000001319 82.0
TH3_k127_4510743_13 Rubrerythrin - - - 0.000000000000003212 76.0
TH3_k127_4510743_14 Repeated motif present between transmembrane helices in cystinosin, yeast ERS1p, mannose-P-dolichol utilization defect 1, and other hypothetical proteins. K15383 - - 0.00000000004793 67.0
TH3_k127_4510743_15 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 0.0000000003413 61.0
TH3_k127_4510743_2 methanogenesis marker protein 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 429.0
TH3_k127_4510743_3 PFAM ABC transporter related K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 412.0
TH3_k127_4510743_4 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 392.0
TH3_k127_4510743_5 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 330.0
TH3_k127_4510743_6 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 312.0
TH3_k127_4510743_7 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002503 267.0
TH3_k127_4510743_8 amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002154 224.0
TH3_k127_4510743_9 - - - - 0.00000000000000000000000000000000000000000000001675 177.0
TH3_k127_4566472_0 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001387 276.0
TH3_k127_4566472_1 tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000005067 188.0
TH3_k127_4566472_2 - - - - 0.000000000000000000000000000000000000000000000003326 181.0
TH3_k127_4566621_0 Anion transporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 580.0
TH3_k127_4566621_1 PFAM Aldehyde dehydrogenase K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 488.0
TH3_k127_4566621_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000006992 163.0
TH3_k127_4566621_3 Psort location Cytoplasmic, score - - - 0.000000000000000000000001517 115.0
TH3_k127_4567230_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.0 1044.0
TH3_k127_4567230_1 DEAD DEAH box helicase domain protein K03725 - - 3.009e-295 920.0
TH3_k127_4567230_10 - - - - 0.0000000000000000000000000000000000000000000000000000214 192.0
TH3_k127_4567230_11 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000000000000001061 164.0
TH3_k127_4567230_12 membrane K09167 - - 0.000000000000000000002875 100.0
TH3_k127_4567230_13 PFAM PKD domain containing protein - - - 0.0000000000001506 85.0
TH3_k127_4567230_14 - - - - 0.0000002628 64.0
TH3_k127_4567230_15 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0007365 43.0
TH3_k127_4567230_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 4.308e-224 704.0
TH3_k127_4567230_3 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.821e-213 666.0
TH3_k127_4567230_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 557.0
TH3_k127_4567230_5 by modhmm - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 494.0
TH3_k127_4567230_6 SMART regulatory protein, Crp K07730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 422.0
TH3_k127_4567230_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 295.0
TH3_k127_4567230_8 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 284.0
TH3_k127_4567230_9 - - - - 0.000000000000000000000000000000000000000000000000000000000003767 237.0
TH3_k127_4651452_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 2.079e-245 775.0
TH3_k127_4651452_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.476e-199 629.0
TH3_k127_4651452_10 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000000000000000000006466 235.0
TH3_k127_4651452_11 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000001682 232.0
TH3_k127_4651452_12 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000002682 220.0
TH3_k127_4651452_13 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000004217 166.0
TH3_k127_4651452_14 Alternative locus ID - - - 0.000000000000000000000000349 121.0
TH3_k127_4651452_15 - - - - 0.00000000000000138 78.0
TH3_k127_4651452_16 Tetratricopeptide repeat - - - 0.000000001515 67.0
TH3_k127_4651452_2 TIGRFAM small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 569.0
TH3_k127_4651452_3 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 445.0
TH3_k127_4651452_4 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 448.0
TH3_k127_4651452_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 409.0
TH3_k127_4651452_6 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 383.0
TH3_k127_4651452_7 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 293.0
TH3_k127_4651452_8 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 288.0
TH3_k127_4651452_9 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002352 299.0
TH3_k127_4695175_0 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 516.0
TH3_k127_4695175_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 397.0
TH3_k127_4695175_2 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 302.0
TH3_k127_4695175_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007531 280.0
TH3_k127_4695175_4 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000000001464 171.0
TH3_k127_4695175_5 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000000000000000004194 159.0
TH3_k127_4695175_6 RNA recognition motif - - - 0.0000000000000000000000000000000002267 136.0
TH3_k127_4695175_7 PFAM Uncharacterised conserved protein UCP006577 - - - 0.00000000000000000000000197 106.0
TH3_k127_4695175_8 PspC domain K03973 - - 0.00000000000000006966 85.0
TH3_k127_4712742_0 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 434.0
TH3_k127_4712742_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 393.0
TH3_k127_4712742_2 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 370.0
TH3_k127_472447_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.86e-240 753.0
TH3_k127_472447_1 PFAM SufBD protein K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 576.0
TH3_k127_472447_10 - - - - 0.0000000000000000000000000000000000000000000000000004812 191.0
TH3_k127_472447_2 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 536.0
TH3_k127_472447_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 513.0
TH3_k127_472447_4 COG0863 DNA modification methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 460.0
TH3_k127_472447_5 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 447.0
TH3_k127_472447_6 PFAM ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 395.0
TH3_k127_472447_7 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 368.0
TH3_k127_472447_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 282.0
TH3_k127_472447_9 PFAM cyclase family protein K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000002385 233.0
TH3_k127_4761857_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 6.966e-240 750.0
TH3_k127_4761857_1 Domain of unknown function (DUF3821) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 407.0
TH3_k127_4761857_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001969 250.0
TH3_k127_4761857_3 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000002916 182.0
TH3_k127_4763637_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 5.657e-226 706.0
TH3_k127_4763637_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.2e-224 701.0
TH3_k127_4763637_10 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 465.0
TH3_k127_4763637_11 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 423.0
TH3_k127_4763637_12 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 437.0
TH3_k127_4763637_13 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 342.0
TH3_k127_4763637_14 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 323.0
TH3_k127_4763637_15 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 315.0
TH3_k127_4763637_16 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 294.0
TH3_k127_4763637_17 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 292.0
TH3_k127_4763637_18 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 287.0
TH3_k127_4763637_19 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 283.0
TH3_k127_4763637_2 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 3.715e-204 644.0
TH3_k127_4763637_20 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002809 282.0
TH3_k127_4763637_21 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000000000000000000000000000000000000000000000000000000000001915 260.0
TH3_k127_4763637_22 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000000000000000000000000000000000000000000000000000006977 233.0
TH3_k127_4763637_23 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.0000000000000000000000000000000000000000000000000000000000000000244 229.0
TH3_k127_4763637_24 PFAM methyltransferase small K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
TH3_k127_4763637_25 archaeal Zn-finger protein - - - 0.0000000000000000000000000000000000000000000000000000000002915 209.0
TH3_k127_4763637_26 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000002377 194.0
TH3_k127_4763637_27 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000000000000000000000000000349 176.0
TH3_k127_4763637_28 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000005877 179.0
TH3_k127_4763637_29 Domain of unknown function (DUF371) K09738 - - 0.000000000000000000000000000000000000000000000001225 178.0
TH3_k127_4763637_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 9.866e-197 622.0
TH3_k127_4763637_30 PFAM thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000002676 174.0
TH3_k127_4763637_31 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000000000000000000000000000000000000003427 171.0
TH3_k127_4763637_32 - - - - 0.0000000000000000000000000000000000000000000007282 168.0
TH3_k127_4763637_33 - - - - 0.000000000000000000000000000000000000000002401 166.0
TH3_k127_4763637_34 Belongs to the PDCD5 family K06875 - - 0.000000000000000000000000000000000000001509 150.0
TH3_k127_4763637_35 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000000000000000000000000000004873 149.0
TH3_k127_4763637_36 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000000000000000000000000000005764 140.0
TH3_k127_4763637_37 - - - - 0.00000000000000000000000000000000004934 142.0
TH3_k127_4763637_38 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000000000006098 124.0
TH3_k127_4763637_39 CRS1_YhbY K07574 - - 0.00000000000000000000000002195 109.0
TH3_k127_4763637_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 569.0
TH3_k127_4763637_40 PFAM Ribosomal LX protein K02944 - - 0.0000000000000000000002388 97.0
TH3_k127_4763637_41 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000001353 91.0
TH3_k127_4763637_42 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001125 86.0
TH3_k127_4763637_43 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000001086 55.0
TH3_k127_4763637_44 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000001135 56.0
TH3_k127_4763637_5 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 558.0
TH3_k127_4763637_6 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 552.0
TH3_k127_4763637_7 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 557.0
TH3_k127_4763637_8 TGS domain protein K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 553.0
TH3_k127_4763637_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 472.0
TH3_k127_4766709_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.059e-295 915.0
TH3_k127_4766709_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.11e-259 805.0
TH3_k127_4766709_10 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K14091,K15831 - - 0.00000000000000000000000000000000000000000006127 164.0
TH3_k127_4766709_11 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K14089 - - 0.0000000000000000000000000000000000000000001329 162.0
TH3_k127_4766709_12 Endonuclease V K05982 - 3.1.21.7 0.000000000000000000000000000000000000000002804 164.0
TH3_k127_4766709_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000000000000019 139.0
TH3_k127_4766709_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000000006063 127.0
TH3_k127_4766709_15 ATP synthase subunit C K02124 - - 0.000000000000000000001526 95.0
TH3_k127_4766709_17 cell adhesion involved in biofilm formation - - - 0.00000000000002426 82.0
TH3_k127_4766709_19 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000048 55.0
TH3_k127_4766709_2 PFAM NADH Ubiquinone plastoquinone (complex I) K14086 - - 4.009e-250 786.0
TH3_k127_4766709_20 H subunit K02107 - - 0.0009028 47.0
TH3_k127_4766709_3 V-type ATPase 116kDa subunit family K02123 - - 9.088e-204 653.0
TH3_k127_4766709_4 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 578.0
TH3_k127_4766709_5 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 410.0
TH3_k127_4766709_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 366.0
TH3_k127_4766709_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 306.0
TH3_k127_4766709_8 FHA domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 289.0
TH3_k127_4766709_9 PFAM NADH ubiquinone oxidoreductase, 20 K14088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000591 271.0
TH3_k127_4856725_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 4.039e-299 926.0
TH3_k127_4856725_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.177e-277 870.0
TH3_k127_4856725_10 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 400.0
TH3_k127_4856725_11 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 381.0
TH3_k127_4856725_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 381.0
TH3_k127_4856725_13 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 360.0
TH3_k127_4856725_14 methylase K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 365.0
TH3_k127_4856725_15 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 361.0
TH3_k127_4856725_16 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 341.0
TH3_k127_4856725_17 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 335.0
TH3_k127_4856725_18 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 329.0
TH3_k127_4856725_19 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 322.0
TH3_k127_4856725_2 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 614.0
TH3_k127_4856725_20 Uroporphyrinogen III synthase HEM4 K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
TH3_k127_4856725_21 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009796 268.0
TH3_k127_4856725_22 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005298 261.0
TH3_k127_4856725_23 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000332 251.0
TH3_k127_4856725_24 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.000000000000000000000000000000000000000000000000000000002514 205.0
TH3_k127_4856725_25 - - - - 0.00000000000000000000000000000000000000000000000000002395 193.0
TH3_k127_4856725_26 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000000000000000000000000000006097 136.0
TH3_k127_4856725_27 protein conserved in archaea - - - 0.0000000000000000000000000000000001247 135.0
TH3_k127_4856725_28 Transcriptional regulator K07108 - - 0.0000000000000000000000000000000005034 133.0
TH3_k127_4856725_29 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000000000000000000002086 115.0
TH3_k127_4856725_3 Domain of unknown function (DUF3821) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 585.0
TH3_k127_4856725_30 transcriptional regulators K03724 - - 0.00000000000000000000000001255 110.0
TH3_k127_4856725_31 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.0000000000000000000000001056 106.0
TH3_k127_4856725_32 nucleic acid binding OB-fold tRNA helicase-type - - - 0.000000000000000000000004324 106.0
TH3_k127_4856725_33 - - - - 0.00000000000000000000003043 106.0
TH3_k127_4856725_34 PBS lyase HEAT-like repeat - - - 0.000000000000000006289 93.0
TH3_k127_4856725_35 - - - - 0.000000000000134 72.0
TH3_k127_4856725_4 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 565.0
TH3_k127_4856725_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 548.0
TH3_k127_4856725_6 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 537.0
TH3_k127_4856725_7 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 448.0
TH3_k127_4856725_8 SMART Elongator protein 3 MiaB NifB K15865 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 431.0
TH3_k127_4856725_9 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 411.0
TH3_k127_4863204_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1716.0
TH3_k127_4863204_1 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 9.683e-282 880.0
TH3_k127_4863204_10 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003196 250.0
TH3_k127_4863204_11 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000007922 172.0
TH3_k127_4863204_12 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000003136 145.0
TH3_k127_4863204_13 - - - - 0.0000000000000000000104 101.0
TH3_k127_4863204_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 4.179e-208 652.0
TH3_k127_4863204_3 Belongs to the peptidase M24B family - - - 1.809e-205 644.0
TH3_k127_4863204_4 domain, Protein K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 563.0
TH3_k127_4863204_5 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 536.0
TH3_k127_4863204_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 324.0
TH3_k127_4863204_7 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 302.0
TH3_k127_4863204_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000472 283.0
TH3_k127_4863204_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000005866 259.0
TH3_k127_4949469_0 P-loop Domain of unknown function (DUF2791) K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 388.0
TH3_k127_4949469_1 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000002315 137.0
TH3_k127_4949469_2 metallopeptidase activity - - - 0.00000000000000000000000002318 116.0
TH3_k127_4998587_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003651 265.0
TH3_k127_4998587_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000001921 103.0
TH3_k127_5119470_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 1.035e-277 864.0
TH3_k127_5119470_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 7.257e-213 674.0
TH3_k127_5119470_10 Type II secretion system (T2SS), protein F K07333 - - 0.0000000000000000000000000000000000000001364 152.0
TH3_k127_5119470_11 - - - - 0.0000000000000000000000000000000000006088 142.0
TH3_k127_5119470_12 - - - - 0.0000000000000000000000000004392 115.0
TH3_k127_5119470_13 Zn-ribbon containing protein K07163 - - 0.000000000000000000000000002003 115.0
TH3_k127_5119470_14 - - - - 0.000000000000000000000001245 107.0
TH3_k127_5119470_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 8.052e-198 628.0
TH3_k127_5119470_3 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 567.0
TH3_k127_5119470_4 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 533.0
TH3_k127_5119470_5 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 340.0
TH3_k127_5119470_6 cytidyltransferase-related domain K00952 - 2.7.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000002771 252.0
TH3_k127_5119470_7 Belongs to the SUI1 family K03113 - - 0.0000000000000000000000000000000000000000000000000000005014 194.0
TH3_k127_5119470_8 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.00000000000000000000000000000000000000000000001052 173.0
TH3_k127_5119470_9 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000001841 186.0
TH3_k127_5141865_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 4.329e-207 649.0
TH3_k127_5141865_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003456 278.0
TH3_k127_5141865_2 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004045 276.0
TH3_k127_5141865_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000001716 237.0
TH3_k127_5141865_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000000000000009235 199.0
TH3_k127_5141865_5 - - - - 0.000000000000000000000000000000000000000002305 163.0
TH3_k127_5141865_6 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000001009 146.0
TH3_k127_5141865_7 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000000000001116 136.0
TH3_k127_5141865_8 Binds to the 23S rRNA K02896 - - 0.000000000000000000000000000009457 119.0
TH3_k127_5141865_9 Tetratricopeptide repeat - - - 0.0000006295 55.0
TH3_k127_5147812_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 4.985e-200 636.0
TH3_k127_5147812_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 4.118e-197 624.0
TH3_k127_5147812_10 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 309.0
TH3_k127_5147812_11 TIGRFAM formate dehydrogenase family accessory protein FdhD K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000002768 238.0
TH3_k127_5147812_12 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000003083 236.0
TH3_k127_5147812_13 protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000647 224.0
TH3_k127_5147812_14 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000006312 214.0
TH3_k127_5147812_15 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000002615 213.0
TH3_k127_5147812_16 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant K07025 - - 0.000000000000000000000000000000000000000000000000000000002564 207.0
TH3_k127_5147812_17 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000001505 198.0
TH3_k127_5147812_18 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000001432 176.0
TH3_k127_5147812_19 Protein of unknown function (DUF2769) - - - 0.00000000000000000000000000000000000000003542 154.0
TH3_k127_5147812_2 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 601.0
TH3_k127_5147812_20 PFAM PRC-barrel domain - - - 0.000000000000000000000000000005384 120.0
TH3_k127_5147812_21 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000001717 106.0
TH3_k127_5147812_22 PFAM Uncharacterised conserved protein UCP006577 - - - 0.00000000000000000002656 93.0
TH3_k127_5147812_23 - - - - 0.0000004439 56.0
TH3_k127_5147812_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 578.0
TH3_k127_5147812_4 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 559.0
TH3_k127_5147812_5 COG0607 Rhodanese-related sulfurtransferase K01011,K01069 - 2.8.1.1,2.8.1.2,3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 552.0
TH3_k127_5147812_6 signal transduction protein with CBS domains K07744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 441.0
TH3_k127_5147812_7 TIGRFAM small GTP-binding protein K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 417.0
TH3_k127_5147812_8 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 386.0
TH3_k127_5147812_9 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 376.0
TH3_k127_5254735_0 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 359.0
TH3_k127_5254735_1 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 329.0
TH3_k127_5254735_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 295.0
TH3_k127_5254735_3 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.0000000000000000000000000000000000000000000000001119 179.0
TH3_k127_5254735_4 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000245 82.0
TH3_k127_5412862_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.393e-243 759.0
TH3_k127_5412862_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 417.0
TH3_k127_5412862_10 Probably involved in the biogenesis of the ribosome K14561 - - 0.00000000000000000002054 96.0
TH3_k127_5412862_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000000000000000000252 90.0
TH3_k127_5412862_2 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 372.0
TH3_k127_5412862_3 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 319.0
TH3_k127_5412862_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000001914 209.0
TH3_k127_5412862_5 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.00000000000000000000000000000000000000000000000002455 186.0
TH3_k127_5412862_6 binds to the 23S rRNA K02921 - - 0.000000000000000000000000000000000000000008872 155.0
TH3_k127_5412862_7 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.000000000000000000000000000000000000007149 151.0
TH3_k127_5412862_8 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000000000000000000000000001856 151.0
TH3_k127_5412862_9 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000153 93.0
TH3_k127_5577364_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 2.488e-211 661.0
TH3_k127_5577364_1 LOR SDH bifunctional enzyme conserved - - - 1.278e-198 627.0
TH3_k127_5577364_10 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 364.0
TH3_k127_5577364_11 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 361.0
TH3_k127_5577364_12 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 346.0
TH3_k127_5577364_13 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 312.0
TH3_k127_5577364_14 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000764 259.0
TH3_k127_5577364_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004684 233.0
TH3_k127_5577364_16 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000001324 224.0
TH3_k127_5577364_17 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.00000000000000000000000000000000000000000000000000000000000001575 220.0
TH3_k127_5577364_18 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215,K03546 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.000000000000000000000000000000000000000000000000000000007987 207.0
TH3_k127_5577364_19 - - - - 0.0000000000000000000000000000000000000000000000000000003826 209.0
TH3_k127_5577364_2 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 541.0
TH3_k127_5577364_20 - - - - 0.0000000000000000000000000000000000000000000000003183 179.0
TH3_k127_5577364_21 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000000000000000002275 156.0
TH3_k127_5577364_22 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000000000000000001165 135.0
TH3_k127_5577364_23 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000107 108.0
TH3_k127_5577364_24 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00000000000000000001176 92.0
TH3_k127_5577364_25 structural constituent of ribosome K02962 - - 0.00000000000000000001667 92.0
TH3_k127_5577364_26 - - - - 0.00002399 50.0
TH3_k127_5577364_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 530.0
TH3_k127_5577364_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 462.0
TH3_k127_5577364_5 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 448.0
TH3_k127_5577364_6 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 432.0
TH3_k127_5577364_7 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 433.0
TH3_k127_5577364_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 427.0
TH3_k127_5577364_9 SMART Elongator protein 3 MiaB NifB K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 409.0
TH3_k127_5633955_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1499.0
TH3_k127_5633955_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.144e-314 973.0
TH3_k127_5633955_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 596.0
TH3_k127_5633955_3 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 400.0
TH3_k127_5633955_4 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 351.0
TH3_k127_5633955_5 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000217 211.0
TH3_k127_5773753_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 2.005e-302 937.0
TH3_k127_5785645_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 425.0
TH3_k127_5785645_1 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000459 225.0
TH3_k127_5785645_2 - - - - 0.0000000000000000000000000000000000000000001654 170.0
TH3_k127_5785645_3 - - - - 0.000000000000000000000000000003298 126.0
TH3_k127_5814082_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.46e-307 971.0
TH3_k127_5814082_1 Protein of unknown function, DUF255 K06888 - - 2.267e-223 713.0
TH3_k127_5814082_10 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 322.0
TH3_k127_5814082_11 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 308.0
TH3_k127_5814082_12 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 297.0
TH3_k127_5814082_13 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 289.0
TH3_k127_5814082_14 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001364 287.0
TH3_k127_5814082_15 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000005537 267.0
TH3_k127_5814082_16 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000237 260.0
TH3_k127_5814082_17 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000006276 247.0
TH3_k127_5814082_18 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.00000000000000000000000000000000000000000000000000000000000002675 220.0
TH3_k127_5814082_19 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000000000001601 213.0
TH3_k127_5814082_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 4.244e-200 630.0
TH3_k127_5814082_20 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000001667 213.0
TH3_k127_5814082_21 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000006605 214.0
TH3_k127_5814082_22 - - - - 0.00000000000000000000000000000000000000000000000000000005591 199.0
TH3_k127_5814082_23 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000006759 197.0
TH3_k127_5814082_24 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.000000000000000000000000000000000000000000000000002588 187.0
TH3_k127_5814082_25 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000008455 182.0
TH3_k127_5814082_26 Small multi-drug export protein - - - 0.00000000000000000000000000000000000000000000000003757 187.0
TH3_k127_5814082_27 Uncharacterized protein conserved in archaea (DUF2121) - - - 0.0000000000000000000000000000000000000000000000002035 185.0
TH3_k127_5814082_28 PFAM Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000000000000000000002327 170.0
TH3_k127_5814082_29 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000002414 158.0
TH3_k127_5814082_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 561.0
TH3_k127_5814082_30 Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000000000000000000008988 160.0
TH3_k127_5814082_31 - - - - 0.000000000000000000000000001651 117.0
TH3_k127_5814082_32 - - - - 0.000000000000000000000000002273 115.0
TH3_k127_5814082_33 - - - - 0.000000000000000003943 90.0
TH3_k127_5814082_35 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000006773 74.0
TH3_k127_5814082_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 535.0
TH3_k127_5814082_5 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 508.0
TH3_k127_5814082_6 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 386.0
TH3_k127_5814082_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 370.0
TH3_k127_5814082_8 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 354.0
TH3_k127_5814082_9 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 353.0
TH3_k127_581572_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1018.0
TH3_k127_581572_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.438e-271 842.0
TH3_k127_581572_10 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007101 266.0
TH3_k127_581572_11 ATP-dependent DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000002943 219.0
TH3_k127_581572_12 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000579 203.0
TH3_k127_581572_13 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000006165 174.0
TH3_k127_581572_14 PIN domain of ribonuclease K07060 - - 0.0000000000000000000000000000000000000000000000921 173.0
TH3_k127_581572_15 PFAM thioesterase superfamily K02614 - - 0.0000000000000000000000000005277 119.0
TH3_k127_581572_16 Sulfur transfer protein involved in thiamine biosynthesis K03154,K21947 GO:0003674,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031386,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070647,GO:0071704,GO:1901564 2.8.1.15 0.00004129 48.0
TH3_k127_581572_2 PFAM chaperonin Cpn60 TCP-1 K22447 - - 2.022e-247 772.0
TH3_k127_581572_3 PFAM amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 606.0
TH3_k127_581572_4 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 424.0
TH3_k127_581572_5 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 388.0
TH3_k127_581572_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 357.0
TH3_k127_581572_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 340.0
TH3_k127_581572_8 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 344.0
TH3_k127_581572_9 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 286.0
TH3_k127_5917324_0 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 362.0
TH3_k127_5917324_1 ATP10 protein - - - 0.00000000000000000000000000000000000001693 150.0
TH3_k127_5917324_2 - - - - 0.000000000000000000001181 99.0
TH3_k127_5917324_3 Belongs to the glutamate synthase family - - - 0.00000000000000000004723 91.0
TH3_k127_5950485_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 5.511e-206 644.0
TH3_k127_5950485_1 PFAM Aminotransferase class I and II K05825 - - 9.472e-199 624.0
TH3_k127_5950485_2 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000002207 246.0
TH3_k127_5950485_3 B-block binding subunit of TFIIIC - - - 0.0000000000000000000000000000000000000000000000359 172.0
TH3_k127_5950485_4 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000000000000006722 131.0
TH3_k127_5950485_5 PFAM Yip1 domain - - - 0.000000000000000000000000000000001038 139.0
TH3_k127_5950485_6 Hsp20/alpha crystallin family K13993 - - 0.000000983 56.0
TH3_k127_6166620_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 442.0
TH3_k127_6166620_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645,K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 440.0
TH3_k127_6166620_2 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 418.0
TH3_k127_6166620_3 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 318.0
TH3_k127_6166620_4 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 294.0
TH3_k127_6166620_5 Helix-turn-helix domain protein K03627 - - 0.0000000000000000000000000000000000000000000000000005236 188.0
TH3_k127_6166620_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00002868 47.0
TH3_k127_6236102_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 4.969e-245 767.0
TH3_k127_6236102_1 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008551 456.0
TH3_k127_6236102_2 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000002787 195.0
TH3_k127_6236102_3 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.00000000000000001139 85.0
TH3_k127_6395486_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1410.0
TH3_k127_6395486_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1251.0
TH3_k127_6395486_10 Belongs to the UPF0280 family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002274 255.0
TH3_k127_6395486_11 PFAM Metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003844 257.0
TH3_k127_6395486_12 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003786 242.0
TH3_k127_6395486_13 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000000000000000000000000000000000000001006 228.0
TH3_k127_6395486_14 PFAM regulatory protein, ArsR K07721 - - 0.000000000000000000000000000000000000000000000000000000000004558 213.0
TH3_k127_6395486_15 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000008208 201.0
TH3_k127_6395486_16 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000001341 190.0
TH3_k127_6395486_17 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000215 171.0
TH3_k127_6395486_18 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000002616 158.0
TH3_k127_6395486_19 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000004848 157.0
TH3_k127_6395486_2 PFAM CBS domain - - - 7.027e-254 790.0
TH3_k127_6395486_20 - - - - 0.0000000000000000000000000000000003866 142.0
TH3_k127_6395486_21 zinc finger, SWIM - - - 0.00000000000000000000000000000004645 128.0
TH3_k127_6395486_22 - - - - 0.0000000000000000000000000007448 117.0
TH3_k127_6395486_23 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.00000000000000000000000003116 111.0
TH3_k127_6395486_24 - - - - 0.0000000000000000000000004275 108.0
TH3_k127_6395486_25 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000001405 83.0
TH3_k127_6395486_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 548.0
TH3_k127_6395486_4 ATP-grasp domain K06913 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 418.0
TH3_k127_6395486_5 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 319.0
TH3_k127_6395486_6 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 318.0
TH3_k127_6395486_7 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 307.0
TH3_k127_6395486_8 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006847 281.0
TH3_k127_6395486_9 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000248 277.0
TH3_k127_6408049_0 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 550.0
TH3_k127_6408049_1 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 538.0
TH3_k127_6408049_2 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 374.0
TH3_k127_6408049_3 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 284.0
TH3_k127_6408049_4 PFAM Peptidase M20 K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000009293 232.0
TH3_k127_64547_0 KH, type 1, domain K07041 - - 0.0 1137.0
TH3_k127_64547_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 572.0
TH3_k127_64547_2 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 395.0
TH3_k127_64547_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 332.0
TH3_k127_64547_4 ATPases associated with a variety of cellular activities K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 316.0
TH3_k127_64547_5 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 311.0
TH3_k127_64547_6 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 294.0
TH3_k127_64547_7 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000326 240.0
TH3_k127_64547_8 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000008077 173.0
TH3_k127_65274_0 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 309.0
TH3_k127_65274_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 291.0
TH3_k127_65274_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002486 283.0
TH3_k127_65274_3 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000175 210.0
TH3_k127_65274_4 protein involved in the oxidation of intracellular sulfur K07235,K07236 - - 0.00000000000000000000000000000000000000000000000000000000002727 220.0
TH3_k127_65274_5 - K07112 - - 0.000000000000000000000000000000000000000000000004012 177.0
TH3_k127_65274_6 Small multi-drug export protein - - - 0.00000000000000000000000000000000001472 144.0
TH3_k127_65274_7 Sodium Bile acid symporter family - - - 0.0000000000001464 77.0
TH3_k127_6563213_0 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 380.0
TH3_k127_6563213_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001221 261.0
TH3_k127_6563213_2 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.0000000000000000000000000000000000000000000000001122 181.0
TH3_k127_6563213_3 transcription factor (CBF NF-Y) - - - 0.0000000000000000000008495 96.0
TH3_k127_6563213_4 - - - - 0.000000000000000002422 88.0
TH3_k127_6563213_5 membrane - - - 0.00000001643 65.0
TH3_k127_6636403_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000004634 195.0
TH3_k127_6636403_1 Tetratricopeptide repeat - - - 0.000003401 58.0
TH3_k127_6636403_2 Papain family cysteine protease K14647 - - 0.000729 44.0
TH3_k127_6671711_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 513.0
TH3_k127_6671711_1 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 302.0
TH3_k127_6735290_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 1.57e-285 882.0
TH3_k127_6735290_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 7.207e-280 868.0
TH3_k127_6735290_10 - - - - 0.00000000009615 69.0
TH3_k127_6735290_2 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 1.686e-254 807.0
TH3_k127_6735290_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 551.0
TH3_k127_6735290_4 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 552.0
TH3_k127_6735290_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 496.0
TH3_k127_6735290_6 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005235 270.0
TH3_k127_6735290_7 RimK domain protein ATP-grasp K05844,K15740 - 6.3.2.33 0.00000000000000000000000000000000000000000000000000000000000000001578 227.0
TH3_k127_6735290_8 Uncharacterised protein family UPF0058 - - - 0.0000000000000000000000000000000000000000481 153.0
TH3_k127_6735290_9 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000005921 101.0
TH3_k127_6791328_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1188.0
TH3_k127_6791328_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.65e-210 663.0
TH3_k127_6791328_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.037e-208 655.0
TH3_k127_6791328_3 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 359.0
TH3_k127_6791328_4 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 363.0
TH3_k127_6791328_5 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 321.0
TH3_k127_6791328_6 COG1940 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 298.0
TH3_k127_6791328_7 PFAM Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 293.0
TH3_k127_6791328_8 META domain - - - 0.000000000000000000000000009409 119.0
TH3_k127_6791328_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000001015 103.0
TH3_k127_6793842_0 PFAM ferredoxin-dependent glutamate synthase - - - 1.719e-294 911.0
TH3_k127_6793842_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 513.0
TH3_k127_6793842_2 4-Hydroxyphenylpyruvate dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 377.0
TH3_k127_6793842_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009533 260.0
TH3_k127_6793842_4 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000000000000001746 237.0
TH3_k127_6795295_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 483.0
TH3_k127_6795295_1 PFAM peptidase U62 modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000001099 148.0
TH3_k127_6795295_2 SigmaK-factor processing regulatory protein BofA K06317 - - 0.00001274 51.0
TH3_k127_6796419_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1036.0
TH3_k127_6796419_1 acid binding OB-fold tRNA helicase-type K07463 - - 1.617e-311 968.0
TH3_k127_6796419_10 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 444.0
TH3_k127_6796419_11 PHP C-terminal domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 435.0
TH3_k127_6796419_12 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 368.0
TH3_k127_6796419_13 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 366.0
TH3_k127_6796419_14 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 363.0
TH3_k127_6796419_15 Membrane protein of unknown function DUF63 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 337.0
TH3_k127_6796419_16 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 325.0
TH3_k127_6796419_17 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 325.0
TH3_k127_6796419_18 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000475 286.0
TH3_k127_6796419_19 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000001606 246.0
TH3_k127_6796419_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.44e-246 764.0
TH3_k127_6796419_20 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000007332 222.0
TH3_k127_6796419_21 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000481 219.0
TH3_k127_6796419_22 Stage II sporulation protein M K06384 - - 0.0000000000000000000000000000000000000000000000000001965 190.0
TH3_k127_6796419_23 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000000000000000000003163 184.0
TH3_k127_6796419_24 Belongs to the UPF0179 family K09730 - - 0.000000000000000000000000000000000000000000000000000382 188.0
TH3_k127_6796419_25 protein conserved in archaea K09723 - - 0.00000000000000000000000000000000000000000000000006203 187.0
TH3_k127_6796419_26 adenyl ribonucleotide binding - - - 0.00000000000000000000000000000000000000000000005206 175.0
TH3_k127_6796419_27 TfuA-like protein - - - 0.000000000000000000000000000000000000001543 156.0
TH3_k127_6796419_28 - - - - 0.00000000000000000000000000000000005217 134.0
TH3_k127_6796419_29 metal-binding protein - - - 0.000000000000000000000000000001255 123.0
TH3_k127_6796419_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 4.356e-232 725.0
TH3_k127_6796419_30 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000003689 99.0
TH3_k127_6796419_31 PFAM Ribosomal protein S27E K02978 - - 0.0000000000000000000001645 98.0
TH3_k127_6796419_32 - - - - 0.0000000000000000000003779 100.0
TH3_k127_6796419_33 PFAM Yip1 domain - - - 0.00000000000000000003213 98.0
TH3_k127_6796419_34 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000009464 71.0
TH3_k127_6796419_4 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 3.133e-231 726.0
TH3_k127_6796419_5 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 609.0
TH3_k127_6796419_6 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 548.0
TH3_k127_6796419_7 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 534.0
TH3_k127_6796419_8 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 531.0
TH3_k127_6796419_9 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 464.0
TH3_k127_6976479_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 6.287e-219 683.0
TH3_k127_6976479_1 PFAM NADP-dependent oxidoreductase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 294.0
TH3_k127_6976479_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001595 280.0
TH3_k127_6976479_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000009535 113.0
TH3_k127_7021792_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1084.0
TH3_k127_7021792_1 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 407.0
TH3_k127_7021792_2 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 367.0
TH3_k127_7021792_3 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 292.0
TH3_k127_7021792_4 4-Hydroxyphenylpyruvate dioxygenase - - - 0.000000000000000000000000000000000000003183 151.0
TH3_k127_7021792_5 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000001437 98.0
TH3_k127_7021792_6 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00003745 46.0
TH3_k127_7081151_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.062e-230 721.0
TH3_k127_7081151_1 DEAD DEAH box helicase K03724 - - 3.822e-228 728.0
TH3_k127_7081151_10 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000007225 143.0
TH3_k127_7081151_11 binds to the 23S rRNA K02922 - - 0.00000000000000000000000003433 108.0
TH3_k127_7081151_12 - - - - 0.000000001762 58.0
TH3_k127_7081151_13 - - - - 0.00000001322 67.0
TH3_k127_7081151_14 PBS lyase HEAT-like repeat - - - 0.0004424 45.0
TH3_k127_7081151_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 6.62e-224 704.0
TH3_k127_7081151_3 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 445.0
TH3_k127_7081151_4 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 400.0
TH3_k127_7081151_5 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001295 270.0
TH3_k127_7081151_6 PFAM PUA domain containing protein K07575 - - 0.000000000000000000000000000000000000000000000000000000000000000009166 228.0
TH3_k127_7081151_7 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000006133 212.0
TH3_k127_7081151_8 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000006725 153.0
TH3_k127_7081151_9 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000000000000000000004615 142.0
TH3_k127_7100833_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1026.0
TH3_k127_7100833_1 - - - - 0.000000000000000000000000000000000000003264 154.0
TH3_k127_711595_0 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 589.0
TH3_k127_711595_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 539.0
TH3_k127_711595_10 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000005734 181.0
TH3_k127_711595_11 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000000000000000000003558 116.0
TH3_k127_711595_12 - - - - 0.00003588 48.0
TH3_k127_711595_2 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 482.0
TH3_k127_711595_3 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 451.0
TH3_k127_711595_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 412.0
TH3_k127_711595_5 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 370.0
TH3_k127_711595_6 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 362.0
TH3_k127_711595_7 Involved in cell shape control K22222 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 321.0
TH3_k127_711595_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000000000000000000000007073 226.0
TH3_k127_711595_9 PFAM sigma-70 region 4 domain protein K09714 - - 0.00000000000000000000000000000000000000000000000000000000000001519 217.0
TH3_k127_7163400_0 PFAM ABC transporter K00400 - - 2.311e-240 754.0
TH3_k127_7163400_1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00581 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 539.0
TH3_k127_7163400_2 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00579 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 413.0
TH3_k127_7163400_3 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00580 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 404.0
TH3_k127_7163400_4 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 289.0
TH3_k127_7163400_5 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000008071 258.0
TH3_k127_7163400_6 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00578 - 2.1.1.86 0.00000000000000000000000000000000001301 138.0
TH3_k127_7163400_7 Belongs to the UPF0251 family K06933 - - 0.000000000000000000000000000000001029 135.0
TH3_k127_7170859_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1472.0
TH3_k127_7170859_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.532e-259 807.0
TH3_k127_7170859_10 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 512.0
TH3_k127_7170859_11 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 430.0
TH3_k127_7170859_12 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 411.0
TH3_k127_7170859_13 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 392.0
TH3_k127_7170859_14 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 377.0
TH3_k127_7170859_15 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 355.0
TH3_k127_7170859_16 Molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 319.0
TH3_k127_7170859_17 tRNAHis guanylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 289.0
TH3_k127_7170859_18 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004062 252.0
TH3_k127_7170859_19 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001201 252.0
TH3_k127_7170859_2 SMART Elongator protein 3 MiaB NifB - - - 1.152e-237 746.0
TH3_k127_7170859_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002487 257.0
TH3_k127_7170859_21 PFAM peptidase zinc-dependent K06974 - - 0.0000000000000000000000000000000000000000000000000000005433 199.0
TH3_k127_7170859_22 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000009562 198.0
TH3_k127_7170859_23 PFAM RDD domain containing protein - - - 0.000000000000000000000000000000000000000000000005821 177.0
TH3_k127_7170859_24 Belongs to the UPF0146 family K09713 - - 0.000000000000000000000000000000000000000009273 158.0
TH3_k127_7170859_25 membrane protein domain - - - 0.0000000000000000000000000000000000000001172 158.0
TH3_k127_7170859_26 PFAM PRC-barrel domain - - - 0.0000000000000000000000000000000002769 133.0
TH3_k127_7170859_27 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.000000000000000000000000000001879 123.0
TH3_k127_7170859_28 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000000000000001099 92.0
TH3_k127_7170859_29 - K03686 - - 0.000000000000000000891 87.0
TH3_k127_7170859_3 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 5.857e-237 747.0
TH3_k127_7170859_30 - - - - 0.0000000000000001664 80.0
TH3_k127_7170859_31 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000002408 64.0
TH3_k127_7170859_4 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 1.152e-234 731.0
TH3_k127_7170859_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 2.909e-198 622.0
TH3_k127_7170859_6 phosphoesterase RecJ domain protein - - - 2.83e-197 626.0
TH3_k127_7170859_7 COG1668 ABC-type Na efflux pump, permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 589.0
TH3_k127_7170859_8 PFAM Aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 571.0
TH3_k127_7170859_9 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 509.0
TH3_k127_7188008_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 1.419e-235 738.0
TH3_k127_7188008_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 9.912e-214 668.0
TH3_k127_7188008_10 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000004472 199.0
TH3_k127_7188008_11 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000000000000000000000000000000000008693 196.0
TH3_k127_7188008_12 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000003074 157.0
TH3_k127_7188008_13 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000000000000000000005545 130.0
TH3_k127_7188008_14 PFAM Yip1 domain - - - 0.0000000000000000000000000005133 121.0
TH3_k127_7188008_15 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000000000000006029 115.0
TH3_k127_7188008_16 Large family of predicted nucleotide-binding domains K07158 - - 0.000000000000000000000000003995 117.0
TH3_k127_7188008_17 CHAT domain - - - 0.00000000000000000000000004114 119.0
TH3_k127_7188008_18 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.000000000000000000000006759 104.0
TH3_k127_7188008_19 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000000001682 94.0
TH3_k127_7188008_2 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 454.0
TH3_k127_7188008_20 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000000002734 94.0
TH3_k127_7188008_21 PBS lyase HEAT-like repeat - - - 0.000000000000000006679 89.0
TH3_k127_7188008_22 - - - - 0.0000000000002331 74.0
TH3_k127_7188008_3 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 378.0
TH3_k127_7188008_4 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 359.0
TH3_k127_7188008_5 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 323.0
TH3_k127_7188008_6 Domain of unknown function (DUF1917) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 298.0
TH3_k127_7188008_7 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 285.0
TH3_k127_7188008_8 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003451 254.0
TH3_k127_7188008_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000003217 223.0
TH3_k127_7348362_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1179.0
TH3_k127_7348362_1 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 374.0
TH3_k127_7348362_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002673 268.0
TH3_k127_7348362_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000001062 208.0
TH3_k127_7348362_4 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000004704 192.0
TH3_k127_7348362_5 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000000000226 78.0
TH3_k127_7348362_6 - - - - 0.0007747 43.0
TH3_k127_7462106_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1275.0
TH3_k127_7462106_1 Belongs to the MCM family K10726 - - 0.0 1095.0
TH3_k127_7462106_10 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 325.0
TH3_k127_7462106_11 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 316.0
TH3_k127_7462106_12 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 306.0
TH3_k127_7462106_13 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004739 278.0
TH3_k127_7462106_14 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009105 270.0
TH3_k127_7462106_15 Pfam:DUF137 K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000001889 252.0
TH3_k127_7462106_16 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000002581 137.0
TH3_k127_7462106_17 protein conserved in archaea K09746 - - 0.000000000000000000000000000002194 130.0
TH3_k127_7462106_18 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000001307 114.0
TH3_k127_7462106_19 - - - - 0.000000000000007458 90.0
TH3_k127_7462106_2 PFAM PKD domain containing protein - - - 5.457e-226 753.0
TH3_k127_7462106_20 - - - - 0.0000000000006985 84.0
TH3_k127_7462106_3 PFAM PKD domain containing protein - - - 5.54e-210 711.0
TH3_k127_7462106_4 PFAM AIR synthase related protein K07388 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 571.0
TH3_k127_7462106_5 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 504.0
TH3_k127_7462106_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 462.0
TH3_k127_7462106_7 Replication factor C K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 368.0
TH3_k127_7462106_8 PFAM TatD-related deoxyribonuclease K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 357.0
TH3_k127_7462106_9 pfam nmd3 K07562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 343.0
TH3_k127_7470486_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 554.0
TH3_k127_7470486_1 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 525.0
TH3_k127_7470486_2 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 369.0
TH3_k127_7470486_3 Dihydrouridine synthase (Dus) - - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
TH3_k127_7470486_4 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000006516 217.0
TH3_k127_7470486_5 Protein of unknown function (DUF447) K09154 - - 0.00000000000000000000000000000000000000000000007131 175.0
TH3_k127_7470486_6 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000000003724 160.0
TH3_k127_7490847_0 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 293.0
TH3_k127_7490847_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002203 233.0
TH3_k127_7490847_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000001651 185.0
TH3_k127_7490847_3 Protein conserved in bacteria - - - 0.0000006255 53.0
TH3_k127_7507412_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 8.809e-288 900.0
TH3_k127_7507412_1 Involved in regulation of DNA replication K10725 - - 1.191e-218 684.0
TH3_k127_7507412_10 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000000000000000000000000000000000000000000000000000000008395 228.0
TH3_k127_7507412_11 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000001995 203.0
TH3_k127_7507412_12 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000000000000000000000000000718 153.0
TH3_k127_7507412_13 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000002454 87.0
TH3_k127_7507412_14 Trm112p-like protein - - - 0.0000000000000000002912 89.0
TH3_k127_7507412_2 PFAM Aminotransferase class I and II K10907 - - 1.744e-196 619.0
TH3_k127_7507412_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 556.0
TH3_k127_7507412_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 507.0
TH3_k127_7507412_5 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 466.0
TH3_k127_7507412_6 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 358.0
TH3_k127_7507412_7 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 338.0
TH3_k127_7507412_8 KH domain protein K06961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009054 269.0
TH3_k127_7507412_9 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000004321 242.0
TH3_k127_7559038_0 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 423.0
TH3_k127_7559038_1 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 397.0
TH3_k127_7559038_2 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 380.0
TH3_k127_7559038_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 375.0
TH3_k127_7559038_4 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002777 279.0
TH3_k127_7559038_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000008566 156.0
TH3_k127_7559038_6 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000005373 108.0
TH3_k127_7559038_7 PFAM ABC transporter K00400 - - 0.000000000000002197 76.0
TH3_k127_7599909_0 Polyphosphate kinase 2 (PPK2) - - - 5.761e-195 621.0
TH3_k127_7599909_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 331.0
TH3_k127_7599909_10 Belongs to the glutamate synthase family - - - 0.0000000000004189 71.0
TH3_k127_7599909_12 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0006154 51.0
TH3_k127_7599909_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 343.0
TH3_k127_7599909_3 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 323.0
TH3_k127_7599909_4 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000004223 180.0
TH3_k127_7599909_5 - - - - 0.00000000000000000000000000000000000000494 151.0
TH3_k127_7599909_6 Chagasin family peptidase inhibitor I42 K14475 - - 0.00000000000000000000000000025 119.0
TH3_k127_7599909_7 PFAM Bacterial protein of - - - 0.0000000000000002095 86.0
TH3_k127_7599909_8 PFAM YHS domain - - - 0.0000000000002325 72.0
TH3_k127_7599909_9 - - - - 0.0000000000003792 75.0
TH3_k127_7644068_0 Sugar (and other) transporter K03446 - - 1.68e-233 731.0
TH3_k127_7644068_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 388.0
TH3_k127_7644068_2 phosphorelay signal transduction system K02584,K07713 - - 0.0000000000000000000000000000000000000000000000000000000006856 208.0
TH3_k127_7644068_3 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K19641 - - 0.00000000005825 64.0
TH3_k127_7689483_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002 278.0
TH3_k127_7689483_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002049 248.0
TH3_k127_7689483_2 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000003163 220.0
TH3_k127_7689483_4 NMT1-like family K02051 - - 0.00000000000000000000000004301 114.0
TH3_k127_7699628_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 3.925e-283 879.0
TH3_k127_7699628_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 1.535e-264 820.0
TH3_k127_7699628_10 - - - - 0.0000004119 54.0
TH3_k127_7699628_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 508.0
TH3_k127_7699628_3 PFAM ABC transporter K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000001559 242.0
TH3_k127_7699628_4 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.00000000000000000000000000000000000000000000000000000000001606 209.0
TH3_k127_7699628_5 PFAM ABC transporter K16786 - - 0.000000000000000000000000000000000000000000000000000000001302 208.0
TH3_k127_7699628_6 PFAM BioY protein K03523 - - 0.00000000000000000000000000000000000000000000000000001804 194.0
TH3_k127_7699628_8 - - - - 0.00000000000000001632 83.0
TH3_k127_7699628_9 PFAM Phage integrase family - - - 0.00000000000000009939 84.0
TH3_k127_7755740_0 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 263.0
TH3_k127_7755740_1 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000001201 182.0
TH3_k127_7755740_2 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000005297 158.0
TH3_k127_7794794_0 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 429.0
TH3_k127_7794794_1 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 383.0
TH3_k127_7794794_2 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000001788 176.0
TH3_k127_7794794_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0009687 42.0
TH3_k127_7893956_0 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 539.0
TH3_k127_7893956_1 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 523.0
TH3_k127_7893956_2 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 430.0
TH3_k127_7893956_3 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001085 289.0
TH3_k127_7893956_4 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001567 290.0
TH3_k127_7893956_5 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000001373 235.0
TH3_k127_7893956_6 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000199 164.0
TH3_k127_7893956_7 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00002975 49.0
TH3_k127_8059340_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 522.0
TH3_k127_8059340_1 N-4 methylation of cytosine K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 503.0
TH3_k127_8059340_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003189 276.0
TH3_k127_8059340_3 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000902 216.0
TH3_k127_8059340_4 PFAM phosphatidate cytidylyltransferase - - - 0.000000000001727 72.0
TH3_k127_8141230_0 Proton-conducting membrane transporter K05568 - - 2.448e-217 685.0
TH3_k127_8141230_1 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 6.946e-195 617.0
TH3_k127_8141230_10 Hydrogenase maturation protease K08315 - 3.4.23.51 0.0000000000000000000000000000000000000006445 153.0
TH3_k127_8141230_11 - - - - 0.00000000000000000000000000000000000001537 149.0
TH3_k127_8141230_12 - - - - 0.00000000000000000000000000000000000001593 155.0
TH3_k127_8141230_13 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.0000000000000000000000000000000000002469 143.0
TH3_k127_8141230_14 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000000002542 130.0
TH3_k127_8141230_15 Multisubunit Na H antiporter, MnhF subunit K05570 - - 0.0000000000000000000002259 98.0
TH3_k127_8141230_16 Domain of unknown function (DUF4040) - - - 0.000000000000000000001584 102.0
TH3_k127_8141230_17 META domain - - - 0.0000000000000000000669 95.0
TH3_k127_8141230_18 Membrane bound hydrogenase - - - 0.000000000000000002016 89.0
TH3_k127_8141230_2 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 610.0
TH3_k127_8141230_3 PFAM respiratory-chain NADH dehydrogenase, subunit 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 387.0
TH3_k127_8141230_4 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18023 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002261 251.0
TH3_k127_8141230_5 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K18017 - 1.12.7.2 0.000000000000000000000000000000000000000000000000000000000003652 216.0
TH3_k127_8141230_6 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.0000000000000000000000000000000000000000000000000000000000087 209.0
TH3_k127_8141230_7 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.000000000000000000000000000000000000000000000000000000007627 203.0
TH3_k127_8141230_8 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.0000000000000000000000000000000000000000000001453 172.0
TH3_k127_8141230_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000002231 162.0
TH3_k127_8195674_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.081e-237 739.0
TH3_k127_8195674_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 6.221e-232 722.0
TH3_k127_8195674_10 COG0607 Rhodanese-related sulfurtransferase K03151 - 2.8.1.4 0.0000000000000000000001128 101.0
TH3_k127_8195674_2 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 592.0
TH3_k127_8195674_3 Protein of unknown function (DUF475) K09799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 465.0
TH3_k127_8195674_4 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 346.0
TH3_k127_8195674_5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 310.0
TH3_k127_8195674_6 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005188 242.0
TH3_k127_8195674_7 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000002464 211.0
TH3_k127_8195674_8 PFAM Desulfoferrodoxin ferrous iron-binding region K05919 - 1.15.1.2 0.000000000000000000000000000000000000000007489 158.0
TH3_k127_8195674_9 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000143 104.0
TH3_k127_822150_0 SMART Elongator protein 3 MiaB NifB K22226 - - 2.668e-203 638.0
TH3_k127_822150_1 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 591.0
TH3_k127_822150_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 391.0
TH3_k127_822150_3 SMART regulatory protein AsnC Lrp family K22225 - - 0.0000000000000000000000000000000000000000000000000000000000000003535 224.0
TH3_k127_822150_4 SMART regulatory protein AsnC Lrp family K22225 - - 0.000000000000000000000000000000000000000000000000000000000002741 213.0
TH3_k127_822150_5 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000004835 164.0
TH3_k127_8270956_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 306.0
TH3_k127_8270956_1 protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000634 209.0
TH3_k127_8270956_2 - - - - 0.0000000000002384 78.0
TH3_k127_8300649_0 PhoU domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 430.0
TH3_k127_8300649_1 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 414.0
TH3_k127_8300649_2 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 310.0
TH3_k127_8300649_3 Thioredoxin - - - 0.0000000000000000000000000000000000000000000007755 168.0
TH3_k127_8300649_4 CARDB domain-containing protein,subtilase family protease - - - 0.000000000000000000000001873 111.0
TH3_k127_8331583_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 327.0
TH3_k127_8331583_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000003336 169.0
TH3_k127_8365608_0 DEAD DEAH box helicase K06877 - - 2.285e-278 877.0
TH3_k127_8365608_1 PFAM Linocin_M18 bacteriocin protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 331.0
TH3_k127_8365608_2 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 308.0
TH3_k127_8365608_3 sugar phosphatases of the HAD superfamily K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001144 273.0
TH3_k127_8365608_4 PFAM PEGA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002874 277.0
TH3_k127_8365608_5 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000008135 205.0
TH3_k127_8365608_6 Rubrerythrin - - - 0.00000000000000000569 85.0
TH3_k127_8421124_0 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 439.0
TH3_k127_8421124_1 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 341.0
TH3_k127_8421124_2 - - - - 0.0000000000000000000000000000000000000000225 160.0
TH3_k127_8424307_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.792e-248 777.0
TH3_k127_8424307_1 PFAM ABC-1 domain protein K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 595.0
TH3_k127_8424307_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 351.0
TH3_k127_8424307_3 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 310.0
TH3_k127_8424307_4 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000004421 139.0
TH3_k127_8424307_5 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000002062 129.0
TH3_k127_8424307_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000003692 97.0
TH3_k127_8424307_7 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.00000000006239 63.0
TH3_k127_8545768_0 - - - - 0.00000000000000000000000000000000000000000000000000001325 196.0
TH3_k127_8545768_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000001185 123.0
TH3_k127_8646395_0 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 596.0
TH3_k127_8646395_1 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 421.0
TH3_k127_8646395_2 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 288.0
TH3_k127_8646395_3 ribosomal protein S15 K02956 - - 0.000000000000000000000000000000000000000000000000000000000000000000004858 236.0
TH3_k127_8646395_4 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000004859 186.0
TH3_k127_8646395_5 Belongs to the UPF0248 family K09715 - - 0.0000000000000000000001675 99.0
TH3_k127_8646395_6 - - - - 0.0000000000000007332 81.0
TH3_k127_8646395_7 DNA binding protein - - - 0.0001211 45.0
TH3_k127_8806238_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 486.0
TH3_k127_8806238_1 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 445.0
TH3_k127_8806238_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000002993 216.0
TH3_k127_8806238_11 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000009864 216.0
TH3_k127_8806238_12 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000000000000000000000000000000043 180.0
TH3_k127_8806238_13 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.00000000000000000000000000000000000000000000006382 171.0
TH3_k127_8806238_14 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000003391 70.0
TH3_k127_8806238_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 358.0
TH3_k127_8806238_3 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 352.0
TH3_k127_8806238_4 PFAM GTP-binding protein HSR1-related K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 347.0
TH3_k127_8806238_5 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 336.0
TH3_k127_8806238_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 287.0
TH3_k127_8806238_7 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005157 258.0
TH3_k127_8806238_8 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003542 251.0
TH3_k127_8806238_9 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001976 239.0
TH3_k127_8816923_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1399.0
TH3_k127_8816923_1 PFAM PilT protein domain protein K06865 - - 4.714e-302 936.0
TH3_k127_8816923_10 COG1403 Restriction endonuclease K10726 - - 0.000000000000000000000000000000000222 137.0
TH3_k127_8816923_11 - - - - 0.0000000000000000000000000000000009928 132.0
TH3_k127_8816923_12 - - - - 0.00000000000000000000003602 107.0
TH3_k127_8816923_13 - - - - 0.000000003203 65.0
TH3_k127_8816923_2 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009375 606.0
TH3_k127_8816923_3 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 362.0
TH3_k127_8816923_4 TIGRFAM cell division ATPase MinD K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 358.0
TH3_k127_8816923_5 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.00000000000000000000000000000000000000000000000000000000000000000000000721 252.0
TH3_k127_8816923_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000000005051 192.0
TH3_k127_8816923_7 Roadblock LC7 K07131 - - 0.000000000000000000000000000000000000000000000000004648 183.0
TH3_k127_8816923_8 Protein of unknown function (DUF473) K09135 - - 0.00000000000000000000000000000000000000000001665 164.0
TH3_k127_8816923_9 - - - - 0.0000000000000000000000000000000000000009405 156.0
TH3_k127_8858636_0 Phosphate transport regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 506.0
TH3_k127_8885832_0 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 346.0
TH3_k127_8885832_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 304.0
TH3_k127_8885832_2 - - - - 0.00000000000000000000000000000000000000000000000000000001433 202.0
TH3_k127_8885832_3 Small Multidrug Resistance protein K11741 - - 0.00000000000000000000000000000000000000001774 164.0
TH3_k127_8885832_4 SpoVT / AbrB like domain - - - 0.0000000000000000000000003117 107.0
TH3_k127_8922413_0 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0 1262.0
TH3_k127_8922413_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 3.94e-221 691.0
TH3_k127_8922413_2 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 329.0
TH3_k127_8922413_3 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000000003315 193.0
TH3_k127_8922413_4 Protein of unknown function DUF86 K07075 - - 0.0000000000000000000000001061 113.0
TH3_k127_8922413_5 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000003244 94.0
TH3_k127_8927129_0 PFAM DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 349.0
TH3_k127_8927129_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000002392 135.0
TH3_k127_8927129_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000003217 151.0
TH3_k127_9119667_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.717e-214 671.0
TH3_k127_9119667_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 602.0
TH3_k127_9119667_10 - - - - 0.0000000000000000000000001346 111.0
TH3_k127_9119667_2 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 412.0
TH3_k127_9119667_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000001381 230.0
TH3_k127_9119667_4 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000000004187 213.0
TH3_k127_9119667_5 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000002483 199.0
TH3_k127_9119667_6 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000004171 164.0
TH3_k127_9119667_7 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000000000000000000000000000000006365 133.0
TH3_k127_9119667_8 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000744 127.0
TH3_k127_9119667_9 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000000000002174 121.0
TH3_k127_9122680_0 Heat shock 70 kDa protein K04043 - - 8.887e-315 972.0
TH3_k127_9122680_1 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 568.0
TH3_k127_9122680_10 COG1881 Phospholipid-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000006734 201.0
TH3_k127_9122680_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000004655 173.0
TH3_k127_9122680_12 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000002589 159.0
TH3_k127_9122680_13 Ribonuclease K03469 - 3.1.26.4 0.0000000000000000000000000000000002736 136.0
TH3_k127_9122680_14 - - - - 0.000000000000000000000000005329 112.0
TH3_k127_9122680_15 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000001341 97.0
TH3_k127_9122680_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 528.0
TH3_k127_9122680_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 463.0
TH3_k127_9122680_4 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 370.0
TH3_k127_9122680_5 RNA methylase K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 367.0
TH3_k127_9122680_6 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 344.0
TH3_k127_9122680_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 338.0
TH3_k127_9122680_8 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000593 239.0
TH3_k127_9122680_9 Functions by promoting the formation of the first peptide bond K03263 - - 0.00000000000000000000000000000000000000000000000000000000000006828 214.0
TH3_k127_9124910_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.729e-244 759.0
TH3_k127_9124910_1 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 356.0
TH3_k127_9124910_2 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001608 268.0
TH3_k127_9124910_3 TIGRFAM ribosomal protein L30P K02907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001461 261.0
TH3_k127_9124910_4 binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000000000000000000000000000000003056 217.0
TH3_k127_9124910_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000004197 197.0
TH3_k127_9124910_6 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000004432 198.0
TH3_k127_9124910_7 PFAM Ribosomal protein K02912 - - 0.0000000000000000000000000000000000000000000005163 170.0
TH3_k127_9209635_0 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 568.0
TH3_k127_9209635_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 559.0
TH3_k127_9209635_10 Yip1 domain - - - 0.0000000000000000000000000000000000000000000004563 175.0
TH3_k127_9209635_11 - - - - 0.0000000000000000001814 92.0
TH3_k127_9209635_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 456.0
TH3_k127_9209635_3 Mediates influx of magnesium ions K03284 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 334.0
TH3_k127_9209635_4 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 308.0
TH3_k127_9209635_5 COG1361 S-layer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 309.0
TH3_k127_9209635_6 PFAM Aldehyde dehydrogenase K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 291.0
TH3_k127_9209635_7 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001743 262.0
TH3_k127_9209635_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000002758 239.0
TH3_k127_9209635_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000002547 190.0
TH3_k127_9214080_0 Belongs to the TPP enzyme family K00158 - 1.2.3.3 1.73e-238 751.0
TH3_k127_9214080_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 307.0
TH3_k127_9214080_10 Belongs to the UPF0305 family - - - 0.0000000000000859 74.0
TH3_k127_9214080_2 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.00000000000000000000000000000000000000000000000000000000000000002984 240.0
TH3_k127_9214080_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000003725 202.0
TH3_k127_9214080_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000002458 183.0
TH3_k127_9214080_5 Molybdopterin converting factor K03635 - 2.8.1.12 0.0000000000000000000000000000000000000001429 154.0
TH3_k127_9214080_6 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000000002953 123.0
TH3_k127_9214080_7 Phosphate-starvation-inducible E - - - 0.0000000000000000000000004361 110.0
TH3_k127_9214080_8 - - - - 0.0000000000000001351 87.0
TH3_k127_9214080_9 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000005657 79.0
TH3_k127_9218891_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 6.232e-252 781.0
TH3_k127_9218891_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 574.0
TH3_k127_9218891_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000000000005974 98.0
TH3_k127_9218891_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 471.0
TH3_k127_9218891_3 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 425.0
TH3_k127_9218891_4 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 351.0
TH3_k127_9218891_5 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 347.0
TH3_k127_9218891_6 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 285.0
TH3_k127_9218891_7 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000009813 180.0
TH3_k127_9218891_8 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000009798 163.0
TH3_k127_9218891_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000000000000002641 127.0
TH3_k127_9329617_0 phosphohydrolase (DHH superfamily) K07097 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 377.0
TH3_k127_9329617_1 PFAM Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000002021 187.0
TH3_k127_9329617_2 - - - - 0.0000000000000000000000000000000001611 136.0
TH3_k127_9339140_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 426.0
TH3_k127_9339140_1 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 302.0
TH3_k127_9339140_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007148 265.0
TH3_k127_9364564_0 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.000000000000000000000000000000000000000000000000000000000000000000327 232.0
TH3_k127_9364564_1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000003384 235.0
TH3_k127_9364564_2 Ras family K06945 - - 0.000000000000000000000000000000000000000001893 162.0
TH3_k127_9364564_3 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000008749 147.0
TH3_k127_9364651_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1620.0
TH3_k127_9364651_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0 1081.0
TH3_k127_9364651_2 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 5.588e-314 966.0
TH3_k127_9364651_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 5.164e-213 665.0
TH3_k127_9364651_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 441.0
TH3_k127_9364651_5 transcription termination protein NusA K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000001799 237.0
TH3_k127_9364651_6 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.0000000000000000000000000000000000000000008397 158.0
TH3_k127_9364651_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000000000000000001079 138.0
TH3_k127_9423204_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.363e-266 829.0
TH3_k127_9423204_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 590.0
TH3_k127_9423204_10 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000187 157.0
TH3_k127_9423204_11 - - - - 0.0000000000000000000000000756 108.0
TH3_k127_9423204_12 PFAM metallophosphoesterase - - - 0.000000002784 68.0
TH3_k127_9423204_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 500.0
TH3_k127_9423204_3 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 441.0
TH3_k127_9423204_4 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 434.0
TH3_k127_9423204_5 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 379.0
TH3_k127_9423204_6 P-loop Domain of unknown function (DUF2791) K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 330.0
TH3_k127_9423204_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001826 261.0
TH3_k127_9423204_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008148 255.0
TH3_k127_9423204_9 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000001555 219.0
TH3_k127_9584051_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1324.0
TH3_k127_9584051_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1135.0
TH3_k127_9584051_10 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 306.0
TH3_k127_9584051_11 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 287.0
TH3_k127_9584051_12 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000006657 185.0
TH3_k127_9584051_13 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000002674 185.0
TH3_k127_9584051_14 hydrolase K04794 - 3.1.1.29 0.000000000000000000000000000000000000000000000002091 175.0
TH3_k127_9584051_15 Belongs to the UPF0147 family K09721 - - 0.0000000000000000000000000000000000000000008215 157.0
TH3_k127_9584051_16 - - - - 0.000000000000000000000000000000000000000568 150.0
TH3_k127_9584051_17 PDGLE domain K02009 - - 0.0000000000000000000000000000000001373 136.0
TH3_k127_9584051_18 Prokaryotic RING finger family 2 - - - 0.00000000000000000000000000002366 120.0
TH3_k127_9584051_19 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.00000000000000000000000009389 110.0
TH3_k127_9584051_2 DEAD DEAH box helicase domain protein K10896 - - 1.432e-296 928.0
TH3_k127_9584051_20 - K02478 - 2.7.13.3 0.00001629 48.0
TH3_k127_9584051_3 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 1.905e-282 876.0
TH3_k127_9584051_4 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 450.0
TH3_k127_9584051_5 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 449.0
TH3_k127_9584051_6 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 418.0
TH3_k127_9584051_7 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 357.0
TH3_k127_9584051_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 318.0
TH3_k127_9584051_9 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 307.0
TH3_k127_962436_0 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 361.0
TH3_k127_962436_1 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 303.0
TH3_k127_962436_2 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000483 174.0
TH3_k127_964164_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 1.51e-205 646.0
TH3_k127_964164_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 295.0
TH3_k127_964164_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000809 83.0