Overview

ID MAG03979
Name TLS1_bin.8
Sample SMP0103
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Acidimicrobiia
Order UBA5794
Family ZC4RG35
Genus JARDZU01
Species
Assembly information
Completeness (%) 88.41
Contamination (%) 3.0
GC content (%) 66.0
N50 (bp) 4,905
Genome size (bp) 2,425,814

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2575

Gene name Description KEGG GOs EC E-value Score Sequence
TLS1_k127_1026775_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 591.0
TLS1_k127_1026775_1 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 445.0
TLS1_k127_1026775_2 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 426.0
TLS1_k127_1026775_3 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000009665 229.0
TLS1_k127_1026775_4 protein containing SIS (Sugar isomerase) phosphosugar binding domain - - - 0.0000000000000000000000000000007303 124.0
TLS1_k127_1043173_0 von Willebrand factor, type A K07114 - - 9.682e-270 884.0
TLS1_k127_1043173_1 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 364.0
TLS1_k127_1043173_2 COG1138 Cytochrome c biogenesis factor K02198 - - 0.000000000000000000000000000000000000000000000000007747 196.0
TLS1_k127_1043173_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000004091 188.0
TLS1_k127_1043173_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000004338 185.0
TLS1_k127_1043173_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000008204 154.0
TLS1_k127_1043173_6 translation initiation factor activity - - - 0.000000000000000000000000000000002797 146.0
TLS1_k127_1043173_7 Dodecin K09165 - - 0.0009028 47.0
TLS1_k127_1053122_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 480.0
TLS1_k127_1053122_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 503.0
TLS1_k127_1053122_2 GTP-binding protein TypA K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 395.0
TLS1_k127_1053122_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000009073 209.0
TLS1_k127_1053122_4 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - 0.000000000000000000000001187 112.0
TLS1_k127_1057127_0 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 443.0
TLS1_k127_1057127_1 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 340.0
TLS1_k127_1057127_11 Ami_3 K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0006108 48.0
TLS1_k127_1057127_2 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000027 258.0
TLS1_k127_1057127_3 mitochondrial respiratory chain complex IV assembly K14998 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000007908 218.0
TLS1_k127_1057127_4 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000005707 204.0
TLS1_k127_1057127_5 Belongs to the thioredoxin family K00384,K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000005338 177.0
TLS1_k127_1057127_6 YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000000000006471 165.0
TLS1_k127_1057127_7 Belongs to the DEAD box helicase family - - - 0.00000000000000003612 91.0
TLS1_k127_1057127_8 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000004235 76.0
TLS1_k127_1057127_9 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000188 63.0
TLS1_k127_1058887_0 transferase activity, transferring alkyl or aryl (other than methyl) groups K22205 - - 0.000000000000000000000000000000000000000000000000000000002949 212.0
TLS1_k127_1058887_1 L-asparaginase II - - - 0.000000000000000000000000000005871 126.0
TLS1_k127_1058887_2 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.000000000000000000001649 106.0
TLS1_k127_1058887_3 Putative bacterial sensory transduction regulator - - - 0.00000000000000008775 92.0
TLS1_k127_1058887_4 protein with SCP PR1 domains - - - 0.00000000001546 74.0
TLS1_k127_1067309_0 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008386 362.0
TLS1_k127_1067309_1 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001162 274.0
TLS1_k127_1067309_2 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000007067 163.0
TLS1_k127_1067309_3 Permeases of the drug metabolite transporter DMT superfamily - - - 0.000000000000000000000000000002124 130.0
TLS1_k127_1067309_4 Putative inner membrane exporter, YdcZ K09936 - - 0.00000000000000000000000000009498 120.0
TLS1_k127_1067309_5 transferase activity, transferring glycosyl groups K18818 - 2.4.1.269 0.0000000000000000000000002434 112.0
TLS1_k127_1067309_6 COG1525 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.0000000000000001664 95.0
TLS1_k127_1071130_0 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000004151 215.0
TLS1_k127_1071130_1 transmembrane transport K02025,K15771 - - 0.000000000000000000000000000000000000000005114 167.0
TLS1_k127_1071130_2 Bacterial extracellular solute-binding protein - - - 0.000006599 57.0
TLS1_k127_1071953_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 295.0
TLS1_k127_1071953_1 COGs COG2380 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000001238 233.0
TLS1_k127_1071953_2 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000000000000000000000000000007047 223.0
TLS1_k127_1071953_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000006863 190.0
TLS1_k127_1071953_4 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000003118 160.0
TLS1_k127_1073772_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 340.0
TLS1_k127_1073772_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000002905 209.0
TLS1_k127_1073772_2 Alanine racemase, C-terminal domain K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000003538 179.0
TLS1_k127_1077860_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 431.0
TLS1_k127_1077860_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 299.0
TLS1_k127_1077860_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000001413 113.0
TLS1_k127_1082491_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1107.0
TLS1_k127_1082491_1 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 469.0
TLS1_k127_1082491_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 373.0
TLS1_k127_1082491_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 343.0
TLS1_k127_1082491_4 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002919 293.0
TLS1_k127_1082491_5 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003513 282.0
TLS1_k127_1082491_6 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003413 269.0
TLS1_k127_1082491_7 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000003021 186.0
TLS1_k127_1082491_8 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.000000000000000000000000000000000000000000003211 175.0
TLS1_k127_1082491_9 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000000002663 101.0
TLS1_k127_1097320_0 Oxidoreductase K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 415.0
TLS1_k127_1097320_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 415.0
TLS1_k127_1097320_2 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 300.0
TLS1_k127_1097320_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 298.0
TLS1_k127_1097320_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005688 276.0
TLS1_k127_1097320_5 PFAM amidohydrolase 2 K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000641 278.0
TLS1_k127_1097320_6 PFAM Bacterial regulatory proteins, gntR family - - - 0.000000000000000000000000000000000002303 146.0
TLS1_k127_1097320_7 2-hydroxy-3-oxopropionate reductase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000005137 147.0
TLS1_k127_1097320_8 Major Facilitator Superfamily - - - 0.000000005736 60.0
TLS1_k127_1098940_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 522.0
TLS1_k127_1111323_0 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000000000000000000000000000000000177 223.0
TLS1_k127_1111323_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000004513 161.0
TLS1_k127_1111323_2 Response regulator receiver domain - - - 0.000000000000000000000000000000885 136.0
TLS1_k127_1114978_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 537.0
TLS1_k127_1114978_1 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000001171 61.0
TLS1_k127_1114978_2 SWIRM domain K11450,K13366,K20182 GO:0000228,GO:0000785,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006275,GO:0006325,GO:0006338,GO:0006355,GO:0006464,GO:0006482,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008156,GO:0008214,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010453,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0011000,GO:0016043,GO:0016569,GO:0016570,GO:0016577,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031494,GO:0031974,GO:0031981,GO:0032451,GO:0032452,GO:0032454,GO:0032991,GO:0033043,GO:0033044,GO:0033169,GO:0033193,GO:0034641,GO:0034645,GO:0036211,GO:0043111,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045005,GO:0045595,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051128,GO:0051171,GO:0051172,GO:0051252,GO:0051276,GO:0051445,GO:0051726,GO:0060194,GO:0060255,GO:0065007,GO:0070013,GO:0070076,GO:0070988,GO:0071514,GO:0071515,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1902681,GO:1903506,GO:2000104,GO:2000112,GO:2000113,GO:2000241,GO:2001141 1.5.3.14,1.5.3.16 0.000001727 54.0
TLS1_k127_1114978_3 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.000004044 51.0
TLS1_k127_1124381_0 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 413.0
TLS1_k127_1124381_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 358.0
TLS1_k127_1124381_2 Ribosomal L27 protein K02899 - - 0.00000000000000000000000006191 117.0
TLS1_k127_1124381_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000005272 102.0
TLS1_k127_1124381_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000003413 98.0
TLS1_k127_1124731_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 586.0
TLS1_k127_1124731_1 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 406.0
TLS1_k127_1124731_2 PFAM FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 323.0
TLS1_k127_1124731_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 314.0
TLS1_k127_1124731_4 Transcriptional regulator - - - 0.000000000000000000000000000599 123.0
TLS1_k127_1124731_6 Protein of unknown function (DUF2752) - - - 0.000000005532 68.0
TLS1_k127_1126950_0 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 427.0
TLS1_k127_1126950_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 408.0
TLS1_k127_1126950_2 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 409.0
TLS1_k127_1126950_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000003204 255.0
TLS1_k127_1126950_4 VanW like protein - - - 0.0000000000000000000000000000000000000000000000000000000003166 226.0
TLS1_k127_1126950_5 - - - - 0.0000000000000000000000000000000000000000000007182 171.0
TLS1_k127_1126950_6 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000005251 148.0
TLS1_k127_1126950_7 RecB family exonuclease K07465 - - 0.00000000005776 72.0
TLS1_k127_1127296_0 COG0189 Glutathione synthase Ribosomal protein S6 modification - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 426.0
TLS1_k127_1127296_1 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 334.0
TLS1_k127_1127296_2 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000001136 186.0
TLS1_k127_1127296_3 Ribosomal protein S6 modification protein - - - 0.0000000000000000000000000000001879 126.0
TLS1_k127_1127296_4 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000007745 74.0
TLS1_k127_1135906_0 TrkA-N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 454.0
TLS1_k127_1135906_1 ABC transporter K06158 - - 0.000000000000000000000000007361 119.0
TLS1_k127_1144293_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.447e-225 717.0
TLS1_k127_1144293_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000001621 226.0
TLS1_k127_1144293_2 Putative adhesin - - - 0.000000001414 67.0
TLS1_k127_114941_0 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 563.0
TLS1_k127_1150443_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003806 281.0
TLS1_k127_1150443_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000001129 186.0
TLS1_k127_1150443_2 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000001649 121.0
TLS1_k127_1150443_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000007024 63.0
TLS1_k127_1156686_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 588.0
TLS1_k127_1156686_1 protein conserved in bacteria K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009582 383.0
TLS1_k127_1156686_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000008077 173.0
TLS1_k127_1163614_0 Glutamine synthetase, beta-Grasp domain K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 4.886e-230 719.0
TLS1_k127_1163614_1 Sterol carrier protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002176 257.0
TLS1_k127_1163614_2 CorA-like Mg2+ transporter protein K03284 - - 0.000000001749 71.0
TLS1_k127_1195242_0 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 551.0
TLS1_k127_1195242_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 314.0
TLS1_k127_1195242_2 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000006145 164.0
TLS1_k127_1195242_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000005029 135.0
TLS1_k127_1195242_4 Ferredoxin K02230 - 6.6.1.2 0.000000000000000000000000000003197 125.0
TLS1_k127_1195242_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.00000000000000000000000000006554 121.0
TLS1_k127_1195242_6 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000006547 90.0
TLS1_k127_1195342_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 7.115e-194 639.0
TLS1_k127_1195342_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 332.0
TLS1_k127_1195342_2 - - - - 0.0000000000000000000000001809 109.0
TLS1_k127_1195342_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000004837 83.0
TLS1_k127_1195342_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000761 73.0
TLS1_k127_1195342_5 regulation of cell shape K04074 - - 0.00001303 55.0
TLS1_k127_1196966_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000003539 261.0
TLS1_k127_1196966_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001548 243.0
TLS1_k127_1196966_2 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000004291 205.0
TLS1_k127_1196966_3 Trm112p-like protein K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000009069 57.0
TLS1_k127_1200051_0 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 474.0
TLS1_k127_1200051_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 389.0
TLS1_k127_1200051_2 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 346.0
TLS1_k127_1200051_3 amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006304 267.0
TLS1_k127_1200051_4 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000009909 224.0
TLS1_k127_1200051_5 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000006301 185.0
TLS1_k127_1206806_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 471.0
TLS1_k127_1206806_1 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004458 256.0
TLS1_k127_1206806_2 Pfam Anion-transporting ATPase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000003978 197.0
TLS1_k127_1206806_3 PFAM Anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000003091 174.0
TLS1_k127_1206806_4 - - - - 0.0000000000000221 79.0
TLS1_k127_1220105_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 307.0
TLS1_k127_1220105_1 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000005886 156.0
TLS1_k127_1220882_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 351.0
TLS1_k127_1220882_1 GGDEF domain - - - 0.00000002216 66.0
TLS1_k127_1220882_2 PAS domain K18350 - 2.7.13.3 0.0000349 55.0
TLS1_k127_1231286_0 arylformamidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 338.0
TLS1_k127_1231286_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 324.0
TLS1_k127_1231286_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 315.0
TLS1_k127_1231286_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000001728 156.0
TLS1_k127_1231286_4 PFAM amidohydrolase 2 - - - 0.0000000000000000005606 88.0
TLS1_k127_1244749_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 608.0
TLS1_k127_1244749_1 DHH family K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003291 279.0
TLS1_k127_1244749_2 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000001594 248.0
TLS1_k127_1244749_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000004679 210.0
TLS1_k127_1244749_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000003675 108.0
TLS1_k127_1244749_5 Protein of unknown function (DUF503) K09764 - - 0.00000000000008317 76.0
TLS1_k127_1244749_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000004043 68.0
TLS1_k127_1247854_0 F420-dependent oxidoreductase, MSMEG_2906 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 400.0
TLS1_k127_1247854_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000002286 233.0
TLS1_k127_1247854_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001177 228.0
TLS1_k127_125931_0 NAT, N-acetyltransferase, of N-acetylglutamate synthase K22478 - 2.3.1.1,2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 496.0
TLS1_k127_125931_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 458.0
TLS1_k127_125931_2 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 373.0
TLS1_k127_125931_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 327.0
TLS1_k127_125931_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 312.0
TLS1_k127_125931_5 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005248 269.0
TLS1_k127_125931_6 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000002008 220.0
TLS1_k127_125931_7 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000785 120.0
TLS1_k127_1267453_0 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 300.0
TLS1_k127_1267453_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001294 269.0
TLS1_k127_1267453_2 Preprotein translocase SecG subunit K03075 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000005579 79.0
TLS1_k127_1268992_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 7.016e-227 725.0
TLS1_k127_1268992_1 - - - - 0.0000000000000000000000000000000000389 141.0
TLS1_k127_1271439_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003798 287.0
TLS1_k127_1271439_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000002259 208.0
TLS1_k127_1271439_2 PFAM penicillin-binding protein transpeptidase K03587 - 3.4.16.4 0.0000000001566 66.0
TLS1_k127_1271439_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0001799 49.0
TLS1_k127_12770_0 fructose-bisphosphate aldolase, class II, yeast E. coli subtype K01624 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 432.0
TLS1_k127_12770_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 378.0
TLS1_k127_12770_2 cellulose binding - - - 0.000000000000001832 80.0
TLS1_k127_12770_3 F420H(2)-dependent quinone reductase - - - 0.00000000000001724 74.0
TLS1_k127_12770_4 Protein of unknown function (DUF454) K09790 - - 0.0000000000003674 77.0
TLS1_k127_12770_5 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000000000008754 74.0
TLS1_k127_1285421_0 ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 438.0
TLS1_k127_1285421_1 exporter of polyketide K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009245 262.0
TLS1_k127_1285421_2 Mazg nucleotide pyrophosphohydrolase - - - 0.000000002436 59.0
TLS1_k127_1306478_0 protein containing SIS (Sugar isomerase) phosphosugar binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 286.0
TLS1_k127_1306478_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001818 264.0
TLS1_k127_1306478_2 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000004467 249.0
TLS1_k127_1306478_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000001207 191.0
TLS1_k127_1306478_4 regulatory protein GntR HTH K03710 - - 0.00000000000000000000000000000000000000000000213 183.0
TLS1_k127_1306478_5 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000006128 149.0
TLS1_k127_1308136_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 2.279e-229 725.0
TLS1_k127_1308136_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 523.0
TLS1_k127_1308136_2 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000103 151.0
TLS1_k127_1308136_3 Protein of unknown function (DUF3156) - - - 0.000000000000000000001062 108.0
TLS1_k127_1336345_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 2600.0
TLS1_k127_1339063_0 Transporter K12942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 527.0
TLS1_k127_1339063_1 COG0471 Di- and tricarboxylate transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 466.0
TLS1_k127_1341710_0 PFAM AhpC TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003218 271.0
TLS1_k127_1341710_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000112 194.0
TLS1_k127_1341710_2 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000001347 181.0
TLS1_k127_1341710_3 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000009188 115.0
TLS1_k127_1342552_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 537.0
TLS1_k127_1342552_1 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000005824 83.0
TLS1_k127_1342552_2 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000001203 65.0
TLS1_k127_1342552_3 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00003529 49.0
TLS1_k127_136358_0 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 303.0
TLS1_k127_136358_1 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002017 248.0
TLS1_k127_136358_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000007658 227.0
TLS1_k127_136358_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000004825 191.0
TLS1_k127_137083_0 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000006389 156.0
TLS1_k127_137083_1 Replication protein - - - 0.000001833 53.0
TLS1_k127_1380798_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.109e-229 739.0
TLS1_k127_1380798_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 433.0
TLS1_k127_1380798_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 417.0
TLS1_k127_1380798_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000004691 197.0
TLS1_k127_1380798_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000003156 136.0
TLS1_k127_1380798_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000001574 119.0
TLS1_k127_1380798_6 Domain of unknown function (DUF4388) - - - 0.000003769 57.0
TLS1_k127_1382056_0 MOSC domain - - - 0.000000000000000000000000008232 111.0
TLS1_k127_1389477_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 481.0
TLS1_k127_1389477_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000008685 223.0
TLS1_k127_139618_0 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002218 265.0
TLS1_k127_139618_1 Pfam:Zinicin_2 - - - 0.0000000000000000000000000000000000000000000000000000000000003609 227.0
TLS1_k127_139618_2 Putative zinc-finger - GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.00000000193 68.0
TLS1_k127_1405544_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 353.0
TLS1_k127_1405544_1 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001479 200.0
TLS1_k127_1405544_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000002957 141.0
TLS1_k127_140627_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.079e-300 936.0
TLS1_k127_140627_1 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 423.0
TLS1_k127_140627_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000001793 59.0
TLS1_k127_1409924_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000009072 227.0
TLS1_k127_1409924_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000002043 233.0
TLS1_k127_1409924_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000001493 188.0
TLS1_k127_1409924_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000001475 168.0
TLS1_k127_1409924_4 response regulator - - - 0.0000000000000000000000000000001245 127.0
TLS1_k127_1409924_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000001942 80.0
TLS1_k127_1432365_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005073 294.0
TLS1_k127_1432365_1 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001844 254.0
TLS1_k127_1432365_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000003575 151.0
TLS1_k127_1432383_0 Belongs to the glycosyl hydrolase 3 family - - - 2.593e-282 887.0
TLS1_k127_1432383_1 Binding-protein-dependent transport systems inner membrane component K02026,K10119,K17243 - - 0.00000000000000000000003226 100.0
TLS1_k127_1449543_0 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000001338 226.0
TLS1_k127_1449543_1 Pfam Aminotransferase class I and II K11358 - 2.6.1.1 0.00000000000000000000906 93.0
TLS1_k127_1449543_2 Bacterial extracellular solute-binding protein K05813 - - 0.000000000000346 82.0
TLS1_k127_1449543_3 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00007814 47.0
TLS1_k127_1456973_0 response regulator, receiver K02483,K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 327.0
TLS1_k127_1456973_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.00000000000000000000000000000000000000000000000005228 182.0
TLS1_k127_1456973_2 Major Facilitator Superfamily - - - 0.00003255 56.0
TLS1_k127_1497834_0 Isocitrate lyase K01637 - 4.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 362.0
TLS1_k127_1497834_1 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 290.0
TLS1_k127_1500438_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 519.0
TLS1_k127_1500438_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004653 271.0
TLS1_k127_1500438_2 AIR synthase related protein, C-terminal domain K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464 6.3.3.1 0.0000000000000000000000000000000000000000000000000000008951 199.0
TLS1_k127_1500438_3 isoleucine patch - - - 0.00000000000000000000000000000000000000000000009507 173.0
TLS1_k127_1510216_0 Amidohydrolase family K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001642 287.0
TLS1_k127_1510216_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000129 283.0
TLS1_k127_1510216_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000003704 171.0
TLS1_k127_1510216_3 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000002496 116.0
TLS1_k127_1510216_4 amine dehydrogenase activity - - - 0.000000001273 70.0
TLS1_k127_1518348_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 2.841e-214 676.0
TLS1_k127_1518348_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000001761 254.0
TLS1_k127_1518348_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000006946 223.0
TLS1_k127_1518348_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000095 93.0
TLS1_k127_153102_0 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 343.0
TLS1_k127_153102_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000306 280.0
TLS1_k127_153102_2 phosphoribosyltransferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000003829 208.0
TLS1_k127_153102_3 homoserine kinase activity - - - 0.00000000000000000000000001046 121.0
TLS1_k127_1534818_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 465.0
TLS1_k127_1534818_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 447.0
TLS1_k127_1534818_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003007 243.0
TLS1_k127_1534818_3 Nudix hydrolase - - - 0.00000000000000000000001106 107.0
TLS1_k127_1534818_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000003467 103.0
TLS1_k127_1534818_5 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 0.00000000000006359 76.0
TLS1_k127_1541654_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.378e-216 680.0
TLS1_k127_1541654_1 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 482.0
TLS1_k127_1541654_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 472.0
TLS1_k127_1541654_3 e3 binding domain K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001282 289.0
TLS1_k127_1547655_0 Hemerythrin HHE cation binding domain K01534 - 3.6.3.3,3.6.3.5 4.85e-224 717.0
TLS1_k127_1547655_1 Uncharacterized protein family (UPF0051) K09014 - - 1.538e-222 697.0
TLS1_k127_1547655_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000001033 244.0
TLS1_k127_1547655_11 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000002582 220.0
TLS1_k127_1547655_12 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000001122 203.0
TLS1_k127_1547655_13 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000001667 199.0
TLS1_k127_1547655_14 purine nucleotide biosynthetic process K02529 - - 0.00000000000000000000000000000000000000000000000009853 193.0
TLS1_k127_1547655_15 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000007437 188.0
TLS1_k127_1547655_16 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000006548 147.0
TLS1_k127_1547655_17 Peptidase family M23 - - - 0.0000000000000003079 86.0
TLS1_k127_1547655_18 Belongs to the UPF0337 (CsbD) family - - - 0.000000002565 64.0
TLS1_k127_1547655_2 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 372.0
TLS1_k127_1547655_3 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 347.0
TLS1_k127_1547655_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 335.0
TLS1_k127_1547655_5 Branched-chain amino acid transport system / permease component K02057,K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 328.0
TLS1_k127_1547655_6 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 302.0
TLS1_k127_1547655_7 Periplasmic binding protein-like domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004579 266.0
TLS1_k127_1547655_8 COG1129 ABC-type sugar transport system, ATPase component K02056,K10441,K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000003528 256.0
TLS1_k127_1547655_9 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008787 251.0
TLS1_k127_1577802_0 TIGRFAM TRAP transporter, DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 468.0
TLS1_k127_1577802_1 TIGRFAM tripartite ATP-independent periplasmic transporter solute receptor, DctP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 367.0
TLS1_k127_1577802_2 Alcohol dehydrogenase GroES-like domain K00001,K00008 - 1.1.1.1,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000005091 274.0
TLS1_k127_1577802_3 Bacterial transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000006065 198.0
TLS1_k127_1577802_4 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.0000000000000000000000000000000000000000003276 161.0
TLS1_k127_1577802_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000009076 106.0
TLS1_k127_1577802_6 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000004522 79.0
TLS1_k127_1580597_0 PFAM extracellular solute-binding protein, family 5 - - - 0.0000000000000000000000000001795 130.0
TLS1_k127_1584128_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 365.0
TLS1_k127_1584128_1 PFAM Transketolase central region K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 362.0
TLS1_k127_1584128_2 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 350.0
TLS1_k127_1584128_3 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000004696 192.0
TLS1_k127_1584128_4 - - - - 0.00000000000000000007995 99.0
TLS1_k127_1608402_0 acetylesterase activity - - - 0.0000000000000000000000000000000000000000002212 181.0
TLS1_k127_1608402_1 OST-HTH/LOTUS domain - - - 0.0000000000000000000002958 98.0
TLS1_k127_1608402_2 - - - - 0.00000000006846 66.0
TLS1_k127_1608402_3 Alpha/beta-hydrolase family - - - 0.0002323 46.0
TLS1_k127_1617826_0 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 305.0
TLS1_k127_1617826_1 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004495 234.0
TLS1_k127_1617826_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000003964 153.0
TLS1_k127_1617826_3 glyoxalase III activity K16260 - - 0.000000000000000000000000000000000000003815 150.0
TLS1_k127_1617826_4 transcriptional - - - 0.0000000000000000000000000000002258 126.0
TLS1_k127_1617826_5 SNARE associated Golgi protein - - - 0.00000000000000000000000001087 122.0
TLS1_k127_1617826_6 - - - - 0.00000000000005462 73.0
TLS1_k127_1627578_0 ATPases associated with a variety of cellular activities K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 358.0
TLS1_k127_1627578_1 Binding-protein-dependent transport system inner membrane component K05846 - - 0.000000000000000000000000000000000000000000007506 168.0
TLS1_k127_1682696_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
TLS1_k127_1682696_1 Glucose dehydrogenase C-terminus K00001,K00344 - 1.1.1.1,1.6.5.5 0.000000000000000000000000000000000000000000000153 189.0
TLS1_k127_1682696_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000001615 175.0
TLS1_k127_1682696_3 EamA-like transporter family - - - 0.000000000000000000000000001284 117.0
TLS1_k127_1691807_0 Sulfatase K01130 GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509 3.1.6.1 1.201e-271 842.0
TLS1_k127_1691807_2 SnoaL-like polyketide cyclase - - - 0.00003749 51.0
TLS1_k127_17141_0 Acyltransferase - - - 0.000000000000000000000000000000000000000000002873 173.0
TLS1_k127_17141_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000007892 108.0
TLS1_k127_17141_2 - - - - 0.00001399 57.0
TLS1_k127_1741477_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 390.0
TLS1_k127_1741477_1 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000003982 256.0
TLS1_k127_1741477_2 F420-0:Gamma-glutamyl ligase K12234 GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000002321 231.0
TLS1_k127_1741477_3 LytR cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000003624 158.0
TLS1_k127_1753112_0 Fumarate reductase flavoprotein C-term K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 423.0
TLS1_k127_1753112_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000598 202.0
TLS1_k127_1753112_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000003277 169.0
TLS1_k127_176273_0 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 317.0
TLS1_k127_176273_1 Belongs to the arylamine N-acetyltransferase family K00675,K15466 - 2.3.1.118 0.00000000000000000000000000000000000000000000000000000000002245 214.0
TLS1_k127_176273_2 Activator of hsp90 atpase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000009414 187.0
TLS1_k127_176273_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000009051 171.0
TLS1_k127_1776960_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 624.0
TLS1_k127_1803669_0 PFAM ABC transporter related K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 302.0
TLS1_k127_1803669_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 289.0
TLS1_k127_1803669_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000002312 212.0
TLS1_k127_1803669_3 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000000000000000000000003522 173.0
TLS1_k127_1803669_4 Protein of unknown function (DUF2587) - - - 0.000000000000000000000000000000000001319 143.0
TLS1_k127_1803669_5 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.0000000000000000000000000002812 116.0
TLS1_k127_182332_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 398.0
TLS1_k127_182332_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.000000000000000000000000000000000004654 141.0
TLS1_k127_182332_2 PFAM Glycosyl transferase family 2 K07027 - - 0.000000000000000000000002961 111.0
TLS1_k127_182332_3 Glycosyltransferase like family 2 - - - 0.0000000000000000001355 105.0
TLS1_k127_182332_4 - - - - 0.0000000000007645 75.0
TLS1_k127_182332_5 Protein of unknown function (DUF3499) - - - 0.0000000851 61.0
TLS1_k127_182332_6 - - - - 0.000003652 59.0
TLS1_k127_1936497_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 398.0
TLS1_k127_1936497_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001117 284.0
TLS1_k127_1936497_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009531 254.0
TLS1_k127_1936497_3 PspC domain - - - 0.0000000000000000000000000000000001073 147.0
TLS1_k127_1936497_4 membrane - - - 0.00000000000006797 76.0
TLS1_k127_1936497_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000001647 65.0
TLS1_k127_1957178_0 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000657 164.0
TLS1_k127_197023_0 aminotransferase class I and II K00812,K10907,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 466.0
TLS1_k127_197023_1 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000007089 252.0
TLS1_k127_197023_2 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000003023 228.0
TLS1_k127_197023_3 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000001596 173.0
TLS1_k127_197023_4 - - - - 0.0000000656 61.0
TLS1_k127_1972394_0 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000134 245.0
TLS1_k127_1972394_1 Domain of unknown function (DUF4032) - - - 0.000000000000000000000000000000000000000000000000000000000000000004472 229.0
TLS1_k127_1972394_2 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000006888 144.0
TLS1_k127_201665_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009619 544.0
TLS1_k127_201665_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 533.0
TLS1_k127_201665_10 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000008605 244.0
TLS1_k127_201665_11 DNA ligase D DNA polymerase LigD K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000006918 226.0
TLS1_k127_201665_12 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000007582 171.0
TLS1_k127_201665_13 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000003418 162.0
TLS1_k127_201665_14 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000006021 154.0
TLS1_k127_201665_15 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000001101 116.0
TLS1_k127_201665_16 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000113 111.0
TLS1_k127_201665_17 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000006261 117.0
TLS1_k127_201665_18 PhoB family transcriptional regulator K02483 - - 0.000000000000000000009543 100.0
TLS1_k127_201665_19 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000001871 100.0
TLS1_k127_201665_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 521.0
TLS1_k127_201665_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000004206 94.0
TLS1_k127_201665_21 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000003398 88.0
TLS1_k127_201665_23 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000005786 59.0
TLS1_k127_201665_24 HEAT repeat - - - 0.000000132 63.0
TLS1_k127_201665_25 LysM domain - - - 0.00000263 54.0
TLS1_k127_201665_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 381.0
TLS1_k127_201665_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 360.0
TLS1_k127_201665_5 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 356.0
TLS1_k127_201665_6 Threonine synthase K01733 GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 338.0
TLS1_k127_201665_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 327.0
TLS1_k127_201665_8 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 315.0
TLS1_k127_201665_9 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001175 267.0
TLS1_k127_2024378_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 1.617e-292 918.0
TLS1_k127_2024378_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 613.0
TLS1_k127_2024378_10 Hydrogenase maturation protease - - - 0.0000000000000000000000000001554 120.0
TLS1_k127_2024378_11 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000005497 119.0
TLS1_k127_2024378_12 translation release factor activity K02835,K15034 - - 0.000000000000000000000002566 107.0
TLS1_k127_2024378_13 hydroperoxide reductase activity - - - 0.00000000000000000000001268 103.0
TLS1_k127_2024378_14 hydroperoxide reductase activity - - - 0.0000000000000000003063 99.0
TLS1_k127_2024378_16 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000004444 65.0
TLS1_k127_2024378_17 - - - - 0.0000000008937 66.0
TLS1_k127_2024378_2 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 600.0
TLS1_k127_2024378_3 Aldo/keto reductase family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 475.0
TLS1_k127_2024378_4 coenzyme F420 hydrogenase activity K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 391.0
TLS1_k127_2024378_5 PFAM Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 321.0
TLS1_k127_2024378_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001666 242.0
TLS1_k127_2024378_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000003886 232.0
TLS1_k127_2024378_8 Putative NAD(P)-binding K03499 - - 0.0000000000000000000000000000000000000000000000000000000003085 210.0
TLS1_k127_2024378_9 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000001501 201.0
TLS1_k127_2031670_0 ABC transporter transmembrane region K06147,K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 569.0
TLS1_k127_2031670_1 ABC transporter transmembrane region K06147,K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 366.0
TLS1_k127_2031670_2 MFS transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 313.0
TLS1_k127_2031670_3 (ABC) transporter K06147,K06148 - - 0.000000000000000000000000000000000000000000000000000001863 196.0
TLS1_k127_2031670_4 carboxymethylenebutenolidase activity - - - 0.000000000000000000000000000000000000007459 153.0
TLS1_k127_2031670_5 - - - - 0.0000008588 53.0
TLS1_k127_2038117_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 498.0
TLS1_k127_2038117_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000383 275.0
TLS1_k127_2038117_10 Belongs to the UPF0102 family K07460 - - 0.00000000001041 71.0
TLS1_k127_2038117_11 Belongs to the UPF0109 family K06960 - - 0.000000001006 65.0
TLS1_k127_2038117_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000005926 241.0
TLS1_k127_2038117_3 Belongs to the RNA methyltransferase TrmD family K00554,K01770 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000002322 237.0
TLS1_k127_2038117_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000196 160.0
TLS1_k127_2038117_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000004079 166.0
TLS1_k127_2038117_6 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000004428 145.0
TLS1_k127_2038117_7 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000003018 112.0
TLS1_k127_2038117_9 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000004988 89.0
TLS1_k127_2071340_0 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 303.0
TLS1_k127_2074329_0 galactosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 332.0
TLS1_k127_2074329_1 Bacterial sugar transferase K13012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004468 272.0
TLS1_k127_2074329_2 - - - - 0.000000000000000000000000000000000000000004794 171.0
TLS1_k127_2074329_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000001363 156.0
TLS1_k127_2074329_4 Formyl transferase - - - 0.0000000000000000000000000000000000002898 154.0
TLS1_k127_2074329_5 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000002799 119.0
TLS1_k127_2074329_6 Glycosyl transferases group 1 K00754 - - 0.000000000000000000000001376 116.0
TLS1_k127_2074329_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00001749 48.0
TLS1_k127_2074671_0 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000001881 57.0
TLS1_k127_2074671_2 Type II secretion system K12511 - - 0.0001439 52.0
TLS1_k127_2091733_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 339.0
TLS1_k127_2091733_1 PAS PAC sensor signal transduction histidine kinase K18350 - 2.7.13.3 0.000000000000000000000000000000000003556 146.0
TLS1_k127_2091733_2 Pfam:DUF385 - - - 0.000000000000000008249 88.0
TLS1_k127_2091733_3 DNA polymerase X family K02347 - - 0.0000000006137 61.0
TLS1_k127_2095837_0 SMART alpha amylase, catalytic sub domain K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 3.304e-305 950.0
TLS1_k127_2095837_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 372.0
TLS1_k127_2101298_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000002402 269.0
TLS1_k127_2101298_1 Ribonuclease III family K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000002849 214.0
TLS1_k127_2101298_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000001153 179.0
TLS1_k127_2101298_3 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000003724 134.0
TLS1_k127_2101298_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000006944 124.0
TLS1_k127_2101298_5 Uncharacterized ACR, COG1399 K07040 GO:0008150,GO:0040007 - 0.000000000000000001405 93.0
TLS1_k127_2101298_6 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000001338 83.0
TLS1_k127_2101298_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000008665 87.0
TLS1_k127_2101298_8 pathogenesis - - - 0.0000000000002658 80.0
TLS1_k127_2101776_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000004906 271.0
TLS1_k127_2101776_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000001636 188.0
TLS1_k127_2101776_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000005396 106.0
TLS1_k127_2101776_3 integration host factor - - - 0.0000000000000003777 85.0
TLS1_k127_2101776_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000008905 76.0
TLS1_k127_2102934_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008614 252.0
TLS1_k127_2102934_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000003192 123.0
TLS1_k127_2102934_2 Fha domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.000000001141 70.0
TLS1_k127_2102934_3 serine threonine protein kinase K03587,K08884,K12132 - 2.7.11.1,3.4.16.4 0.0000004569 61.0
TLS1_k127_2102934_4 TIR domain - - - 0.0001151 52.0
TLS1_k127_2105212_0 Belongs to the peptidase M24B family K01271,K01274 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 348.0
TLS1_k127_2105212_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 341.0
TLS1_k127_2105212_2 Peptidoglycan-binding - - - 0.000000000000000000000000000000004288 143.0
TLS1_k127_2105212_3 - - - - 0.00000000000000000000000000787 126.0
TLS1_k127_2105212_4 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000003728 110.0
TLS1_k127_2105212_5 cellulase activity K00077 - 1.1.1.169 0.0000000000000527 85.0
TLS1_k127_211204_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 444.0
TLS1_k127_211204_1 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 436.0
TLS1_k127_211204_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 391.0
TLS1_k127_211204_3 Oligopeptide/dipeptide transporter, C-terminal region K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 372.0
TLS1_k127_2121408_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000003311 209.0
TLS1_k127_2121408_1 ECF sigma factor K03088 - - 0.0000000000000000000000005475 111.0
TLS1_k127_2121408_2 Evidence 2b Function of strongly homologous gene - - - 0.000000000000005421 75.0
TLS1_k127_2121408_3 META domain - - - 0.0001308 55.0
TLS1_k127_212460_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 541.0
TLS1_k127_212460_1 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 456.0
TLS1_k127_212460_10 PFAM Flavodoxin K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000874 185.0
TLS1_k127_212460_11 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000005035 167.0
TLS1_k127_212460_12 FCD - - - 0.000000000000000000000000000000000000000009791 162.0
TLS1_k127_212460_13 histidinol dehydrogenase activity K15509 - 1.1.1.308 0.0000000000000000000000344 102.0
TLS1_k127_212460_2 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 351.0
TLS1_k127_212460_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 353.0
TLS1_k127_212460_4 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 338.0
TLS1_k127_212460_5 Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 298.0
TLS1_k127_212460_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 310.0
TLS1_k127_212460_7 transport systems K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002713 277.0
TLS1_k127_212460_8 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000007568 251.0
TLS1_k127_212460_9 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000001975 237.0
TLS1_k127_2128347_0 PFAM YibE F-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003598 256.0
TLS1_k127_2128347_1 VanW like protein - - - 0.0000000000000000000000000000000000000000000003065 179.0
TLS1_k127_2128347_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000009653 160.0
TLS1_k127_2181044_0 AMP-forming long-chain acyl-CoA synthetase K01897 - 6.2.1.3 5.716e-199 632.0
TLS1_k127_2181044_1 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000007691 103.0
TLS1_k127_2201089_0 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000006593 190.0
TLS1_k127_2201089_1 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000001091 130.0
TLS1_k127_2201089_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006323,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051276,GO:0060255,GO:0065007,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 - 0.00000000000000001561 87.0
TLS1_k127_2207312_0 MafB19-like deaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000002913 225.0
TLS1_k127_2207312_1 enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000001547 221.0
TLS1_k127_2207312_2 Cell envelope-related transcriptional attenuator domain - - - 0.0000000000000000000000000000000000000000000000001053 190.0
TLS1_k127_2207312_3 - - - - 0.0000000000001896 78.0
TLS1_k127_2233136_0 Glutamate-ammonia ligase adenylyltransferase K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 554.0
TLS1_k127_2233136_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 526.0
TLS1_k127_2233136_2 amidohydrolase K01436 - - 0.0000000000000000000000000000003237 128.0
TLS1_k127_2233136_3 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.000000000000000000000000002947 121.0
TLS1_k127_2244696_0 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 462.0
TLS1_k127_2250799_0 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 446.0
TLS1_k127_2250799_1 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000002256 159.0
TLS1_k127_2250799_2 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000434 100.0
TLS1_k127_2250799_3 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000004056 99.0
TLS1_k127_2250799_4 - - - - 0.000000109 61.0
TLS1_k127_2261661_0 xanthine dehydrogenase activity K03520 - 1.2.5.3 0.0 1447.0
TLS1_k127_2261661_1 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 445.0
TLS1_k127_2261661_10 - - - - 0.00000000000000000000000000000000000000003559 157.0
TLS1_k127_2261661_11 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000003366 149.0
TLS1_k127_2261661_12 - - - - 0.0000000000000000000000000000007814 129.0
TLS1_k127_2261661_13 - - - - 0.0000000000000000000000000007735 117.0
TLS1_k127_2261661_14 - - - - 0.00000000000000000000000006367 114.0
TLS1_k127_2261661_16 - - - - 0.000000000002068 74.0
TLS1_k127_2261661_2 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 447.0
TLS1_k127_2261661_3 Dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 385.0
TLS1_k127_2261661_4 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 357.0
TLS1_k127_2261661_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 289.0
TLS1_k127_2261661_6 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004132 276.0
TLS1_k127_2261661_7 Mazg nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000002114 226.0
TLS1_k127_2261661_8 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000116 221.0
TLS1_k127_2261661_9 - - - - 0.000000000000000000000000000000000000000000000000000001163 201.0
TLS1_k127_2267978_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 379.0
TLS1_k127_2269025_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 354.0
TLS1_k127_2269025_1 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001181 286.0
TLS1_k127_2269025_2 LytR cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000341 114.0
TLS1_k127_2269025_3 CAAX amino terminal protease family K07052 - - 0.0001367 53.0
TLS1_k127_2269907_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 335.0
TLS1_k127_2269907_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004118 271.0
TLS1_k127_2269907_2 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000003539 115.0
TLS1_k127_2275599_0 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000162 175.0
TLS1_k127_2275599_1 Scaffold protein Nfu NifU - - - 0.00000005643 58.0
TLS1_k127_2276598_0 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004848 269.0
TLS1_k127_2276598_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000003678 179.0
TLS1_k127_2276598_2 LVIVD repeat - - - 0.0000000000000000000000000000008324 126.0
TLS1_k127_2276598_3 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 0.0000000000000000002874 93.0
TLS1_k127_227913_0 Isochorismatase family K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000009557 226.0
TLS1_k127_227913_1 DEAD-like helicases superfamily - - - 0.000000000000000000000000000000000000000000001742 173.0
TLS1_k127_227913_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000008565 154.0
TLS1_k127_2280100_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.706e-247 779.0
TLS1_k127_2280100_1 oxidation-reduction process - - - 0.0000000000000000000000000000000000003683 150.0
TLS1_k127_2285415_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.1e-321 994.0
TLS1_k127_2285415_1 Prokaryotic glutathione synthetase, ATP-grasp domain K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 436.0
TLS1_k127_2285415_10 positive regulation of macromolecule biosynthetic process - - - 0.0000000000000006375 86.0
TLS1_k127_2285415_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 409.0
TLS1_k127_2285415_3 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009642 269.0
TLS1_k127_2285415_4 DUF1704 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001947 267.0
TLS1_k127_2285415_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005464 241.0
TLS1_k127_2285415_6 membrane K07149 - - 0.00000000000000000000000000000000000000000000000000000000000103 223.0
TLS1_k127_2285415_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000002732 184.0
TLS1_k127_2285415_8 membrane transporter protein K07090 - - 0.0000000000000000000000000000001125 134.0
TLS1_k127_2285415_9 PFAM PspC domain protein K03973 - - 0.00000000000000000000000000007103 121.0
TLS1_k127_2302695_0 PFAM Uncharacterised ACR, COG1259 K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000051 180.0
TLS1_k127_2302695_1 Belongs to the peptidase S11 family K07258 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 0.0000000000000000000000000000000000000000000000009205 191.0
TLS1_k127_2302695_2 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000003067 175.0
TLS1_k127_2302695_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000004681 151.0
TLS1_k127_2302695_4 Cytidylate kinase-like family K00760 - 2.4.2.8 0.0000000000000000000000000000000000987 144.0
TLS1_k127_2302695_5 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.2.10 0.0000000000000000000000000000000003116 138.0
TLS1_k127_2302695_6 PFAM regulatory protein, MerR - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000002378 96.0
TLS1_k127_2308889_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 6.842e-222 698.0
TLS1_k127_2308889_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 3.193e-204 655.0
TLS1_k127_2308889_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.0000000000000000000000000003794 118.0
TLS1_k127_2308889_3 Zn peptidase - - - 0.0000000000000000000000000006799 128.0
TLS1_k127_2308889_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000002946 106.0
TLS1_k127_2308889_5 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.00000000000000000001796 100.0
TLS1_k127_2308889_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000000005126 59.0
TLS1_k127_2308889_7 Uncharacterized ACR, COG1430 K09005 - - 0.000008054 52.0
TLS1_k127_2323063_0 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 584.0
TLS1_k127_2323063_1 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 343.0
TLS1_k127_23450_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 434.0
TLS1_k127_23450_1 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K09972,K10041 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 403.0
TLS1_k127_23450_2 amino acid transport K02029,K09970,K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000001998 240.0
TLS1_k127_23450_3 Pfam Amidohydrolase K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000005987 177.0
TLS1_k127_23450_4 enzyme of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.0000000000000000000000000000000000000000000006049 180.0
TLS1_k127_2352808_0 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009017 243.0
TLS1_k127_2352808_1 PFAM Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000001174 234.0
TLS1_k127_2352808_2 PFAM transcriptional regulator PadR family protein K10947 - - 0.0000000000000000000000000000000001643 135.0
TLS1_k127_2352808_3 cellular response to DNA damage stimulus K07340 - - 0.00000000000000001409 94.0
TLS1_k127_2355736_0 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000956 277.0
TLS1_k127_2355736_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000002912 154.0
TLS1_k127_2355736_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015595,GO:0015606,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072488,GO:0097159,GO:0097367,GO:0098533,GO:0098655,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1902047,GO:1902494,GO:1902495,GO:1903711,GO:1904949,GO:1990351 3.6.3.31 0.000002353 55.0
TLS1_k127_2363714_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 471.0
TLS1_k127_2363714_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 319.0
TLS1_k127_2363714_2 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 294.0
TLS1_k127_2363714_3 - - - - 0.000000000000000000000000000000000000000000000009527 177.0
TLS1_k127_2363714_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000002212 175.0
TLS1_k127_2363714_5 - - - - 0.00000000000000000000000000000000106 139.0
TLS1_k127_2363714_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000002876 134.0
TLS1_k127_2374771_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001754 236.0
TLS1_k127_2374771_1 sequence-specific DNA binding K00567,K13529,K15051 - 2.1.1.63,3.2.2.21 0.000000000000000000000000000000000000000000000000000000002557 211.0
TLS1_k127_2374771_2 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000002198 55.0
TLS1_k127_2386420_0 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 358.0
TLS1_k127_2386420_1 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000002521 267.0
TLS1_k127_2386420_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000003734 158.0
TLS1_k127_2386420_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000002942 142.0
TLS1_k127_2386420_4 transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000001357 87.0
TLS1_k127_2389245_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 458.0
TLS1_k127_2389245_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 436.0
TLS1_k127_2389245_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000002093 211.0
TLS1_k127_2389245_3 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.0000000000000000000000000000000000000000000000000000001496 197.0
TLS1_k127_2389245_4 Peptidase family M50 - - - 0.0000000000000000000000000000169 128.0
TLS1_k127_2400226_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 337.0
TLS1_k127_2400226_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000001752 237.0
TLS1_k127_2400226_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01996 - - 0.0000000000000000000000000000000000000001574 150.0
TLS1_k127_2400226_3 Threonyl and Alanyl tRNA synthetase second additional domain K07050 - - 0.000000000000000000000000000000009726 131.0
TLS1_k127_2400226_4 ThiJ PfpI - - - 0.000000000000000000001968 101.0
TLS1_k127_2411642_0 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 388.0
TLS1_k127_2411642_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 348.0
TLS1_k127_2411642_2 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 314.0
TLS1_k127_2411642_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002349 261.0
TLS1_k127_2411642_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000009375 202.0
TLS1_k127_2411642_5 Daunorubicin resistance ABC transporter ATP-binding subunit K01990,K18232 - - 0.00000000000000000000000000000000000000000000000001623 183.0
TLS1_k127_2411642_6 SnoaL-like domain - - - 0.000000000000000000000001728 108.0
TLS1_k127_2420797_0 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 501.0
TLS1_k127_2420797_1 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 419.0
TLS1_k127_2420797_2 Arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 361.0
TLS1_k127_2420797_3 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 353.0
TLS1_k127_2420797_4 Psort location Cytoplasmic, score 8.87 K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 334.0
TLS1_k127_2420797_5 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000001171 174.0
TLS1_k127_2420797_6 Domain of unknown function (DUF4870) K09940 - - 0.00000000000000005506 85.0
TLS1_k127_2429701_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 400.0
TLS1_k127_2429701_1 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 372.0
TLS1_k127_2429701_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 302.0
TLS1_k127_2429701_3 Haemolysin-III related K11068 - - 0.0000000000000000000000000000001697 131.0
TLS1_k127_2429701_4 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000004238 108.0
TLS1_k127_2429701_5 Glycosyltransferase Family 4 - - - 0.0000003954 53.0
TLS1_k127_24318_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 465.0
TLS1_k127_24318_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000812 214.0
TLS1_k127_2444988_0 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000002363 207.0
TLS1_k127_2444988_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000005657 198.0
TLS1_k127_2444988_2 PFAM Mandelate racemase muconate lactonizing protein K01856,K01860 - 5.5.1.1,5.5.1.7 0.000000000000000000000000000003159 129.0
TLS1_k127_2444988_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K02528,K16924 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 0.00000000000000000000000000004997 131.0
TLS1_k127_2444988_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.0000000000000000000004403 100.0
TLS1_k127_2444988_5 AbrB family K06284 - - 0.000000000000004437 87.0
TLS1_k127_2457516_0 DNA polymerase beta thumb K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003298 259.0
TLS1_k127_2457516_1 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone - - - 0.0000000000000000000009247 96.0
TLS1_k127_2464861_0 Cytochrome b/b6/petB K03891 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 399.0
TLS1_k127_2464861_1 Cytochrome b(C-terminal)/b6/petD - - - 0.0000000000000000000000000000000000000000000000000000000005656 216.0
TLS1_k127_2464861_10 Cytochrome C oxidase, mono-heme subunit/FixO - - - 0.00000005837 63.0
TLS1_k127_2464861_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000003319 201.0
TLS1_k127_2464861_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000002231 162.0
TLS1_k127_2464861_4 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000004418 159.0
TLS1_k127_2464861_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000001518 157.0
TLS1_k127_2464861_6 FAD binding domain K21401 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 1.3.99.38 0.0000000000000000000000000000000001033 138.0
TLS1_k127_2464861_7 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 0.000000000000000000001093 109.0
TLS1_k127_2464861_8 Cytochrome c - - - 0.00000000001692 76.0
TLS1_k127_2464861_9 Glutaredoxin-like domain (DUF836) - - - 0.00000004266 58.0
TLS1_k127_2465074_0 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 477.0
TLS1_k127_2465074_1 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000002701 229.0
TLS1_k127_2465074_2 HNH nucleases - - - 0.000000005111 62.0
TLS1_k127_2467582_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 288.0
TLS1_k127_2467582_1 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000001227 179.0
TLS1_k127_2467582_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000005882 153.0
TLS1_k127_249903_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 610.0
TLS1_k127_249903_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 464.0
TLS1_k127_249903_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 362.0
TLS1_k127_249903_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000001162 237.0
TLS1_k127_249903_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000004894 130.0
TLS1_k127_249903_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000001996 106.0
TLS1_k127_249903_6 NADH ubiquinone oxidoreductase 24 kD subunit K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000001243 75.0
TLS1_k127_2533032_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 338.0
TLS1_k127_2533032_1 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000006344 155.0
TLS1_k127_2548902_0 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002384 265.0
TLS1_k127_2548902_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000005919 207.0
TLS1_k127_2548902_2 SpoU rRNA Methylase family K03437 - - 0.00000000000000000000000000000000000000000000000000008601 202.0
TLS1_k127_2548902_3 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000114 165.0
TLS1_k127_2548902_4 snoRNA binding - - - 0.000000313 55.0
TLS1_k127_2561686_0 Dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.95e-216 684.0
TLS1_k127_2561686_1 Amidohydrolase family K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000003922 232.0
TLS1_k127_2561686_2 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000001077 237.0
TLS1_k127_2561686_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000153 134.0
TLS1_k127_2561686_4 CAAX protease self-immunity K07052 - - 0.0000000000000001439 89.0
TLS1_k127_2599048_0 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 550.0
TLS1_k127_2599048_1 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 444.0
TLS1_k127_2599048_2 Amino acid amide ABC transporter, ATP-binding protein, 1, HAAT family K01995,K11957 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 292.0
TLS1_k127_2599048_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000007548 261.0
TLS1_k127_2599048_4 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000001215 234.0
TLS1_k127_2599048_6 Cupin 2, conserved barrel domain protein K00450,K01628 - 1.13.11.4,4.1.2.17 0.0000005313 61.0
TLS1_k127_2602860_0 RNA polymerase sigma factor, sigma-70 family K03090 - - 0.0000000000000000000000000000000000000000000000000002058 198.0
TLS1_k127_2602860_1 phosphoserine phosphatase activity - - - 0.00000000000000000000000000001152 135.0
TLS1_k127_260965_0 AP endonuclease family 2 C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 462.0
TLS1_k127_260965_1 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 452.0
TLS1_k127_260965_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 398.0
TLS1_k127_260965_3 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 376.0
TLS1_k127_260965_4 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 339.0
TLS1_k127_2624258_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 4.2.1.9 6.405e-233 732.0
TLS1_k127_2624258_1 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000003306 209.0
TLS1_k127_2624258_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000006016 184.0
TLS1_k127_2624258_3 RDD family - - - 0.000000000000000000000000000000000003712 149.0
TLS1_k127_2633842_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 0.000000000000000000000000000000000000000000000118 176.0
TLS1_k127_2633842_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000009421 141.0
TLS1_k127_2641664_0 pfkB family carbohydrate kinase K00882 - 2.7.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000003516 254.0
TLS1_k127_2641664_1 Survival protein SurE K03787 - 3.1.3.5 0.0000000000000000000000000000000000000131 161.0
TLS1_k127_2661044_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 7.787e-315 986.0
TLS1_k127_2661044_1 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 480.0
TLS1_k127_2661044_10 Pfam Beta-lactamase superfamily domain - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.0000000000000000000000000000000000000000000004088 179.0
TLS1_k127_2661044_11 Transcriptional regulator K13652 - - 0.000000000000000000000000000000000000000008752 160.0
TLS1_k127_2661044_12 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000334 170.0
TLS1_k127_2661044_13 Pfam:DUF385 - - - 0.000000000000000000000000000000003439 135.0
TLS1_k127_2661044_14 ferredoxin K05337 - - 0.000000000000000000000000001378 114.0
TLS1_k127_2661044_15 Protein of unknown function (DUF983) - - - 0.000000000000000000000000073 111.0
TLS1_k127_2661044_16 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000269 117.0
TLS1_k127_2661044_17 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000001206 106.0
TLS1_k127_2661044_18 Phosphoribosyl transferase domain K00764 - 2.4.2.14 0.0000000000001349 78.0
TLS1_k127_2661044_19 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00005332 45.0
TLS1_k127_2661044_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 374.0
TLS1_k127_2661044_3 ATPases associated with a variety of cellular activities K09812 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
TLS1_k127_2661044_4 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003161 279.0
TLS1_k127_2661044_5 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005504 276.0
TLS1_k127_2661044_6 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000004074 259.0
TLS1_k127_2661044_7 Pfam:PNPOx_C K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000001431 235.0
TLS1_k127_2661044_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000002123 197.0
TLS1_k127_2661044_9 Chemotaxis protein CheY K02479 - - 0.00000000000000000000000000000000000000000000002527 179.0
TLS1_k127_2691023_0 E1-E2 ATPase K12952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003883 245.0
TLS1_k127_2691023_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009852 244.0
TLS1_k127_2744568_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000008451 190.0
TLS1_k127_2744568_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000009389 110.0
TLS1_k127_2744568_2 Rhodanese Homology Domain - - - 0.0000000000000000005251 89.0
TLS1_k127_2769432_0 ABC transporter K06147 - - 3.442e-277 875.0
TLS1_k127_2769432_1 ABC transporter K06147 - - 3.258e-263 822.0
TLS1_k127_2769432_2 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 336.0
TLS1_k127_2769432_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000003262 139.0
TLS1_k127_2769432_4 - - - - 0.00000000000000000000000003335 116.0
TLS1_k127_2799894_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 319.0
TLS1_k127_2799894_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000316 239.0
TLS1_k127_2799894_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000001265 57.0
TLS1_k127_2828382_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 290.0
TLS1_k127_2828382_1 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006524 284.0
TLS1_k127_2828382_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009444 267.0
TLS1_k127_2828382_3 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000001907 247.0
TLS1_k127_2828382_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000327 111.0
TLS1_k127_2828382_5 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 - 2.3.1.180 0.0000000000000003647 83.0
TLS1_k127_2831408_0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 525.0
TLS1_k127_2831408_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 509.0
TLS1_k127_2831408_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 309.0
TLS1_k127_2831408_3 Belongs to the glycosyl hydrolase 3 family K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000001726 117.0
TLS1_k127_2831408_4 Polymer-forming cytoskeletal - - - 0.00000000001154 77.0
TLS1_k127_285580_0 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 429.0
TLS1_k127_285580_1 2-hydroxy-3-oxopropionate reductase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 359.0
TLS1_k127_285580_3 Periplasmic binding protein-like domain K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 307.0
TLS1_k127_285580_4 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000006676 212.0
TLS1_k127_285580_5 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000002341 164.0
TLS1_k127_285580_6 Alpha/beta hydrolase of unknown function (DUF1100) - GO:0006582,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009987,GO:0018958,GO:0019438,GO:0019748,GO:0030638,GO:0030640,GO:0042438,GO:0042440,GO:0044237,GO:0044249,GO:0044550,GO:0046148,GO:0046189,GO:0071704,GO:0090487,GO:1901360,GO:1901362,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.00000000000000000000000003782 122.0
TLS1_k127_2856589_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 4.242e-218 689.0
TLS1_k127_2856589_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000002298 175.0
TLS1_k127_2856589_2 DNA polymerase III K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000003486 142.0
TLS1_k127_2904967_0 Belongs to the EPSP synthase family. MurA subfamily K00790 GO:0008150,GO:0040007 2.5.1.7 0.00000000000000000000000000000000000000000000000000002553 192.0
TLS1_k127_2904967_1 GTPase activity K07588 - - 0.000000000000000000000000000000000001648 141.0
TLS1_k127_2904967_2 SpoIID LytB domain protein K06381 - - 0.000000000000000000000000000000001474 147.0
TLS1_k127_2904967_3 Nitrogen fixation protein NifU - - - 0.00000000000000001483 85.0
TLS1_k127_2944820_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 461.0
TLS1_k127_2944820_1 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004496 259.0
TLS1_k127_2944820_2 lactoylglutathione lyase activity - - - 0.000000006463 58.0
TLS1_k127_2945804_0 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.00000000000000002534 92.0
TLS1_k127_2969823_0 PspC domain - - - 0.000000000000000000000000001147 126.0
TLS1_k127_2969823_1 helix_turn_helix, Lux Regulon - - - 0.0007044 46.0
TLS1_k127_2999812_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 323.0
TLS1_k127_2999812_1 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000001332 207.0
TLS1_k127_2999812_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000005578 167.0
TLS1_k127_3014705_0 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000001264 233.0
TLS1_k127_3014705_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000001035 195.0
TLS1_k127_3014705_2 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000619 145.0
TLS1_k127_3014705_3 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564 5.1.1.4 0.000000000000718 69.0
TLS1_k127_3045068_0 TIGRFAM 2-oxoglutarate dehydrogenase, E2 component K00658,K09699 - 2.3.1.168,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 301.0
TLS1_k127_3045068_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000002699 192.0
TLS1_k127_3054068_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 441.0
TLS1_k127_3054068_1 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 354.0
TLS1_k127_3054068_2 ABC transporter K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 359.0
TLS1_k127_3054068_3 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 - 3.3.1.1 0.00000000000000000000000000002747 123.0
TLS1_k127_3054068_4 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.00000000000000000000001902 104.0
TLS1_k127_3059645_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 595.0
TLS1_k127_3059645_1 Xaa-Pro aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 332.0
TLS1_k127_3059645_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004228 259.0
TLS1_k127_3060774_0 Glycosyl Transferase - - - 1.727e-242 773.0
TLS1_k127_3060774_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 302.0
TLS1_k127_3060774_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000001517 258.0
TLS1_k127_3060774_3 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000002387 105.0
TLS1_k127_3063260_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009919 555.0
TLS1_k127_3063260_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000001585 253.0
TLS1_k127_3063260_2 - - - - 0.000000000000000000000000000000000000123 152.0
TLS1_k127_3064962_0 Binding-protein-dependent transport system inner membrane component K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 377.0
TLS1_k127_3064962_1 TOBE domain K02017,K02018 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 375.0
TLS1_k127_3064962_2 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 285.0
TLS1_k127_3064962_3 Transcriptional regulator PadR-like family - - - 0.0000000000000000000004586 100.0
TLS1_k127_3070024_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001201 281.0
TLS1_k127_3070024_1 Histidine kinase K07711 - 2.7.13.3 0.0000000000000000000000000005111 128.0
TLS1_k127_3070024_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00663,K03790 - 2.3.1.128,2.3.1.82 0.000000000000000000000000001369 114.0
TLS1_k127_3071696_0 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001966 282.0
TLS1_k127_3071696_1 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002865 287.0
TLS1_k127_3071696_2 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000002672 147.0
TLS1_k127_3071696_3 Belongs to the peptidase S8 family - - - 0.0000000000000000000009963 111.0
TLS1_k127_3071696_4 - - - - 0.000005072 56.0
TLS1_k127_3082690_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 1.231e-222 697.0
TLS1_k127_3082690_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 441.0
TLS1_k127_3082690_2 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 295.0
TLS1_k127_3082690_3 ATPases associated with a variety of cellular activities K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000003706 241.0
TLS1_k127_3082690_4 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000441 240.0
TLS1_k127_3082690_5 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000005414 157.0
TLS1_k127_3082690_6 YbaK prolyl-tRNA synthetase associated - - - 0.0000000000009318 70.0
TLS1_k127_3085419_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 471.0
TLS1_k127_3085419_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 431.0
TLS1_k127_3085419_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
TLS1_k127_3085419_3 PFAM LemA K03744 - - 0.00000000000000000000000000000000000000000000000000000001301 202.0
TLS1_k127_3085419_4 membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000002008 214.0
TLS1_k127_3085419_5 MDMPI C-terminal domain - - - 0.00000000000000000000000003286 118.0
TLS1_k127_3085419_6 Uncharacterized BCR, YaiI/YqxD family COG1671 K09768 - - 0.0000000000000002036 94.0
TLS1_k127_3101797_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812,K08351 - 1.7.2.3 2.87e-255 804.0
TLS1_k127_3101797_1 drug exporters of the RND superfamily K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 371.0
TLS1_k127_3109740_0 amino acid transport K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 344.0
TLS1_k127_3109740_1 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 305.0
TLS1_k127_3109740_2 Polar amino acid transport system K02028 - 3.6.3.21 0.000000000000000000003689 106.0
TLS1_k127_3118584_0 DNA polymerase alpha chain like domain K02337 - 2.7.7.7 0.0 1184.0
TLS1_k127_3118584_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1029.0
TLS1_k127_3118584_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000001468 254.0
TLS1_k127_3118584_3 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000009068 184.0
TLS1_k127_3118584_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.4.23.36 0.000000000000000000001351 104.0
TLS1_k127_3118584_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000007227 81.0
TLS1_k127_3118584_6 Belongs to the UPF0235 family - - - 0.0000001103 57.0
TLS1_k127_3121606_0 Aminomethyltransferase folate-binding domain K15066 - 2.1.1.341 3.174e-218 685.0
TLS1_k127_3121606_1 PrpF protein K16514 - 5.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 456.0
TLS1_k127_3121606_2 GlcNAc-PI de-N-acetylase K16515 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 317.0
TLS1_k127_3121606_3 Aldolase/RraA K02553,K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004918 269.0
TLS1_k127_3121606_4 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000001917 91.0
TLS1_k127_3124234_0 FAD binding domain - - - 2.3e-217 682.0
TLS1_k127_3124234_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000001065 184.0
TLS1_k127_3141918_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004083 277.0
TLS1_k127_3141918_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000006914 245.0
TLS1_k127_3141918_2 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.000000002705 58.0
TLS1_k127_3145645_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 297.0
TLS1_k127_3145645_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0008150,GO:0040007 4.2.1.113 0.000000000006079 70.0
TLS1_k127_3145645_2 Cytochrome c K00406 - - 0.00000001428 62.0
TLS1_k127_3171320_0 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 406.0
TLS1_k127_3171320_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 342.0
TLS1_k127_3171320_2 - - - - 0.000003359 57.0
TLS1_k127_3178441_0 alpha amylase, catalytic K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 368.0
TLS1_k127_3178441_1 Domain of unknown function (DUF2383) - - - 0.000000000000000000000000000000000005507 141.0
TLS1_k127_3178441_2 - - - - 0.00000000000000000000000000000000007923 145.0
TLS1_k127_3178441_3 - K00368,K18683 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.00000000000000000000002017 106.0
TLS1_k127_3178441_4 - - - - 0.0002984 50.0
TLS1_k127_3187645_0 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000009125 169.0
TLS1_k127_3187645_1 Secreted repeat of unknown function - - - 0.000000000000000000000000000007326 126.0
TLS1_k127_3187645_2 Anti-sigma-K factor rskA - - - 0.000001784 56.0
TLS1_k127_3191988_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008846 286.0
TLS1_k127_3191988_1 Glycoprotease family K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000002491 157.0
TLS1_k127_3191988_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06925 GO:0008150,GO:0040007 - 0.000000000000000000000000000000001059 136.0
TLS1_k127_3191988_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000004204 117.0
TLS1_k127_3191988_4 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.00000000000000008561 83.0
TLS1_k127_3212237_0 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 469.0
TLS1_k127_3212237_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000001852 180.0
TLS1_k127_3212237_2 Involved in formation and maintenance of cell shape K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963 - 0.000000003361 68.0
TLS1_k127_3213124_0 protein histidine kinase activity K03320 - - 0.00000000000000000000000000000000000000000003353 178.0
TLS1_k127_3213124_1 phosphorelay signal transduction system - - - 0.0000000000004822 74.0
TLS1_k127_3213124_2 Membrane-bound serine protease (ClpP class) K07403 - - 0.000001973 58.0
TLS1_k127_3215706_0 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 307.0
TLS1_k127_3215706_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000009983 176.0
TLS1_k127_3215706_2 -O-antigen - - - 0.0000000000000003163 84.0
TLS1_k127_3223840_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 2.221e-205 667.0
TLS1_k127_3223840_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 443.0
TLS1_k127_3223840_2 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 439.0
TLS1_k127_3223840_3 Bacterial extracellular solute-binding protein K10117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 424.0
TLS1_k127_3233854_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.77e-232 730.0
TLS1_k127_3233854_1 YidE YbjL duplication domain protein K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 524.0
TLS1_k127_3233854_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 288.0
TLS1_k127_3233854_3 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004081 233.0
TLS1_k127_3233854_4 PLD-like domain - - - 0.000000000000000000000000000000000000000000000001541 177.0
TLS1_k127_3233854_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000001294 172.0
TLS1_k127_3233854_6 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000009766 117.0
TLS1_k127_3238473_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.602e-231 730.0
TLS1_k127_3238473_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000007563 238.0
TLS1_k127_3238473_2 Nickel-containing superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000001264 206.0
TLS1_k127_3238473_3 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000002868 197.0
TLS1_k127_3238473_4 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000002108 148.0
TLS1_k127_3238473_5 PFAM amino acid-binding ACT domain protein - - - 0.000000000000008907 80.0
TLS1_k127_3238473_6 EamA-like transporter family - - - 0.00000000000006745 82.0
TLS1_k127_3238473_7 Putative transmembrane protein (PGPGW) - - - 0.0000003468 55.0
TLS1_k127_3239596_0 transcriptional regulator - - - 0.0000000000000000000000000000003102 133.0
TLS1_k127_3239596_1 Alpha/beta hydrolase family - - - 0.000000000000000000000001158 106.0
TLS1_k127_3239596_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051,K15553 - - 0.0000000000001731 74.0
TLS1_k127_3239596_3 - - - - 0.000000009624 66.0
TLS1_k127_3246508_0 RNA pseudouridylate synthase K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000001244 234.0
TLS1_k127_3246508_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000001185 169.0
TLS1_k127_3246508_2 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000001259 160.0
TLS1_k127_3246508_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000001416 165.0
TLS1_k127_3246508_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.0000000000000002056 84.0
TLS1_k127_3246508_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000005011 81.0
TLS1_k127_3246508_6 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000006076 56.0
TLS1_k127_3254208_0 Belongs to the group II decarboxylase family K01580 - 4.1.1.15 2.512e-211 666.0
TLS1_k127_3254208_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000001792 128.0
TLS1_k127_3254208_2 Protein of unknown function (DUF1269) - - - 0.000000000000009732 74.0
TLS1_k127_3257108_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1251.0
TLS1_k127_3257108_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 542.0
TLS1_k127_3257108_2 Histidinol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 386.0
TLS1_k127_3257108_3 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000008315 175.0
TLS1_k127_3257108_4 Transcriptional regulator - - - 0.00000000000000000000000000000000005699 144.0
TLS1_k127_3257108_5 - - - - 0.000000000002682 77.0
TLS1_k127_3281596_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 339.0
TLS1_k127_3281596_1 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 329.0
TLS1_k127_3281596_2 META domain - - - 0.000000000000000000000000000000000000002944 154.0
TLS1_k127_3281596_3 RmuC family K09760 - - 0.0000000000000000000000000000000000001507 155.0
TLS1_k127_3281596_4 flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000482 142.0
TLS1_k127_3281596_5 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000002651 130.0
TLS1_k127_3281596_6 SnoaL-like domain K06893 - - 0.00000000000003082 83.0
TLS1_k127_328191_0 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001065 279.0
TLS1_k127_328191_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000001316 158.0
TLS1_k127_328191_2 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000000000000000002859 114.0
TLS1_k127_3291776_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 444.0
TLS1_k127_3291776_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000001437 233.0
TLS1_k127_3291776_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000001472 177.0
TLS1_k127_3291776_3 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000002869 135.0
TLS1_k127_3316156_0 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002868 252.0
TLS1_k127_3316156_1 ABC transporter - - - 0.00000000000000000000000000000000000000000000143 174.0
TLS1_k127_3316156_2 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000003998 155.0
TLS1_k127_3316806_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006461 272.0
TLS1_k127_3316806_1 PFAM PHP domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.000000000000000000000000000000000000000000000000000000000000000000009403 243.0
TLS1_k127_3316806_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000008642 146.0
TLS1_k127_3316806_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000002365 61.0
TLS1_k127_3322105_0 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K15893 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000006127 267.0
TLS1_k127_3322105_1 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000366 159.0
TLS1_k127_3322810_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 356.0
TLS1_k127_3322810_1 EamA-like transporter family - - - 0.00000001654 61.0
TLS1_k127_3323276_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000001897 255.0
TLS1_k127_3323276_1 Cytidylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001582 223.0
TLS1_k127_3323276_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000005631 177.0
TLS1_k127_3324189_0 beta-1,4-mannooligosaccharide phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 508.0
TLS1_k127_3324189_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 340.0
TLS1_k127_3324189_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 312.0
TLS1_k127_3328169_0 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 356.0
TLS1_k127_3328169_1 - - - - 0.00000000000000000000000000000000000000000000138 169.0
TLS1_k127_3328169_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000003196 129.0
TLS1_k127_333054_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.8 1.788e-249 794.0
TLS1_k127_333054_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 452.0
TLS1_k127_333054_10 branched-chain amino acid - - - 0.0000000000000001622 89.0
TLS1_k127_333054_11 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000004126 68.0
TLS1_k127_333054_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 377.0
TLS1_k127_333054_3 impB/mucB/samB family K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000857 276.0
TLS1_k127_333054_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000008537 249.0
TLS1_k127_333054_5 Pfam Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000006271 143.0
TLS1_k127_333054_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000007108 145.0
TLS1_k127_333054_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000365 136.0
TLS1_k127_333054_8 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000003326 109.0
TLS1_k127_333054_9 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000002269 89.0
TLS1_k127_3331195_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 438.0
TLS1_k127_3331195_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000001003 188.0
TLS1_k127_3354624_0 PFAM chorismate K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 448.0
TLS1_k127_3354624_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000005863 164.0
TLS1_k127_3354624_2 Nitroreductase family - - - 0.0000000000000000000001099 114.0
TLS1_k127_3354624_3 ABC transporter K01990,K13926 - - 0.0000000002108 62.0
TLS1_k127_3370312_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 434.0
TLS1_k127_3370312_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000001641 181.0
TLS1_k127_3377539_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 354.0
TLS1_k127_3377539_1 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000002457 228.0
TLS1_k127_3377539_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000002782 124.0
TLS1_k127_3377539_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.00000002336 66.0
TLS1_k127_3377539_4 Amidohydrolase K03392 - 4.1.1.45 0.0000002544 57.0
TLS1_k127_3377539_5 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00001334 57.0
TLS1_k127_340321_0 ketone body catabolic process K01026 - 2.8.3.1 4.496e-204 647.0
TLS1_k127_340321_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 432.0
TLS1_k127_340321_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001603 284.0
TLS1_k127_340321_3 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001465 247.0
TLS1_k127_340321_4 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000002585 175.0
TLS1_k127_340321_5 Protein of unknown function (DUF993) - - - 0.00000000000000001139 85.0
TLS1_k127_340321_6 PFAM EAL domain - - - 0.000000000000282 82.0
TLS1_k127_340321_7 Resolvase - - - 0.000002544 52.0
TLS1_k127_3404103_0 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 348.0
TLS1_k127_3404103_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000001546 279.0
TLS1_k127_3404103_2 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000008154 157.0
TLS1_k127_3404103_3 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000002748 76.0
TLS1_k127_3408654_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 398.0
TLS1_k127_3408654_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001235 266.0
TLS1_k127_341130_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 584.0
TLS1_k127_341130_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 0.0000000000000000000000000000000000000000000002666 172.0
TLS1_k127_341130_2 Belongs to the UPF0312 family - - - 0.0000001901 57.0
TLS1_k127_3451586_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001621 282.0
TLS1_k127_3451586_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000002717 98.0
TLS1_k127_3451586_2 Immunoglobulin-like domain of bacterial spore germination - - - 0.000000000000125 83.0
TLS1_k127_3464422_0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 299.0
TLS1_k127_3464422_1 Belongs to the helicase family. UvrD subfamily - - - 0.0000000000000000000000000000000000000000005538 170.0
TLS1_k127_3468368_0 - - - - 0.00000000000000000000000000000000000000000000000000000000003458 214.0
TLS1_k127_3468368_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000007751 217.0
TLS1_k127_3468368_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000001409 177.0
TLS1_k127_3468368_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000009464 112.0
TLS1_k127_3468368_4 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000005506 112.0
TLS1_k127_3468368_5 UV-endonuclease UvdE - - - 0.000000000000000000003415 106.0
TLS1_k127_3502985_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 411.0
TLS1_k127_3502985_1 PFAM Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000006513 163.0
TLS1_k127_3502985_2 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000003386 77.0
TLS1_k127_3503631_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 374.0
TLS1_k127_3503631_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000007196 166.0
TLS1_k127_3503631_2 transporter solute receptor, DctP family - - - 0.000000000000000000000000000000000005363 156.0
TLS1_k127_3503631_3 Mannose-6-phosphate isomerase - - - 0.0000000000000000000007315 99.0
TLS1_k127_3503631_4 Malate/L-lactate dehydrogenase - - - 0.0000000001055 65.0
TLS1_k127_3520133_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 563.0
TLS1_k127_3520133_1 Chlorophyllase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006623 272.0
TLS1_k127_3520133_2 Thiol-disulfide isomerase-like thioredoxin K02199 - - 0.0000000000000000000000000000000000000000000000000003109 191.0
TLS1_k127_3520133_3 subunit of a heme lyase K02200 - - 0.0000000000000000004203 99.0
TLS1_k127_3520133_4 Domain of unknown function (DUF4440) - - - 0.000000000000000001656 90.0
TLS1_k127_3520133_5 photosynthesis K12132,K20543 - 2.7.11.1 0.000000000000002092 88.0
TLS1_k127_3540157_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 493.0
TLS1_k127_3540157_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 426.0
TLS1_k127_3540157_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000001203 263.0
TLS1_k127_3540157_3 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0001614 44.0
TLS1_k127_3548212_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003357 286.0
TLS1_k127_3548212_1 Putative undecaprenyl diphosphate synthase K00806,K12503 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000004283 251.0
TLS1_k127_3548212_2 alpha-ribazole phosphatase activity K02226,K15634 - 3.1.3.73,5.4.2.12 0.0000000000000000000000000000000000000000000000000644 187.0
TLS1_k127_3548212_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000001018 134.0
TLS1_k127_3548212_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000005735 55.0
TLS1_k127_3548212_5 COG0006 Xaa-Pro aminopeptidase K01262 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 0.0000009448 51.0
TLS1_k127_3589154_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 434.0
TLS1_k127_3589154_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005736 277.0
TLS1_k127_3589154_10 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002561 116.0
TLS1_k127_3589154_11 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000875 115.0
TLS1_k127_3589154_12 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000001677 106.0
TLS1_k127_3589154_13 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000001014 81.0
TLS1_k127_3589154_14 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000002064 57.0
TLS1_k127_3589154_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001396 260.0
TLS1_k127_3589154_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000003121 224.0
TLS1_k127_3589154_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000009793 213.0
TLS1_k127_3589154_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000004495 164.0
TLS1_k127_3589154_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000004293 160.0
TLS1_k127_3589154_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000009284 139.0
TLS1_k127_3589154_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000001395 136.0
TLS1_k127_3589154_9 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000001903 128.0
TLS1_k127_3596483_0 Aminomethyltransferase folate-binding domain K15064 - - 6.112e-214 674.0
TLS1_k127_3596483_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 567.0
TLS1_k127_3596483_10 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000001595 219.0
TLS1_k127_3596483_11 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000227 211.0
TLS1_k127_3596483_12 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000008748 208.0
TLS1_k127_3596483_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000624 199.0
TLS1_k127_3596483_14 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000004121 180.0
TLS1_k127_3596483_15 branched-chain amino acid transport system, permease component K01998 - - 0.000000000000000000000000000000000000000001538 170.0
TLS1_k127_3596483_16 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.000000000000000000000000000000000000000003356 176.0
TLS1_k127_3596483_17 Alpha beta hydrolase K01055,K14727 - 3.1.1.24,4.1.1.44 0.000000000000000000000000000000000000001312 151.0
TLS1_k127_3596483_18 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000001226 159.0
TLS1_k127_3596483_19 Catalyzes the formation of protocatechuate from 4-hydroxybenzoate K00481 - 1.14.13.2 0.00000000000000000000000001979 111.0
TLS1_k127_3596483_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 434.0
TLS1_k127_3596483_20 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000006671 99.0
TLS1_k127_3596483_21 protocatechuate 3,4-dioxygenase K00449 - 1.13.11.3 0.000000000000000001043 94.0
TLS1_k127_3596483_22 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000001864 82.0
TLS1_k127_3596483_3 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 311.0
TLS1_k127_3596483_4 protocatechuate 3,4-dioxygenase, beta subunit' K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001574 274.0
TLS1_k127_3596483_5 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002998 250.0
TLS1_k127_3596483_6 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000002851 245.0
TLS1_k127_3596483_7 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000001051 232.0
TLS1_k127_3596483_8 Adenylosuccinate lyase C-terminus K01857 - 5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000009468 233.0
TLS1_k127_3596483_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000006486 222.0
TLS1_k127_3615570_0 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 478.0
TLS1_k127_3615570_1 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000000000000000000000001096 159.0
TLS1_k127_3615570_2 Protein of unknown function DUF45 K07043 - - 0.000000000000003281 76.0
TLS1_k127_3615570_3 competence protein COMEC K01174,K13277 - 3.1.31.1 0.00000001954 66.0
TLS1_k127_3630208_0 amino acid transport K09969 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 488.0
TLS1_k127_3630208_1 amino acid transport K09970,K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001668 288.0
TLS1_k127_3631338_0 SMART Metal-dependent phosphohydrolase, HD region K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 373.0
TLS1_k127_3631338_1 organic phosphonate transmembrane transporter activity K02042 - - 0.0000000000000000000000000000000000000000000000001968 199.0
TLS1_k127_3631338_2 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000003008 145.0
TLS1_k127_3631338_3 ABC transporter K01990 - - 0.000000000000002767 77.0
TLS1_k127_3641266_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.753e-281 877.0
TLS1_k127_3641266_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000197 231.0
TLS1_k127_3641266_2 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000001572 218.0
TLS1_k127_3641266_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000001333 205.0
TLS1_k127_3641266_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000001309 192.0
TLS1_k127_3641266_5 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000004935 138.0
TLS1_k127_3641266_6 oligoendopeptidase F - - - 0.00000000000000000000000004765 125.0
TLS1_k127_3661418_0 UDP binding domain K02474,K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 384.0
TLS1_k127_3661418_1 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000001594 217.0
TLS1_k127_3661418_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000007391 179.0
TLS1_k127_3661418_3 SpoIID LytB domain protein - - - 0.0000000000000000000000000000000000008061 159.0
TLS1_k127_3661418_4 Belongs to the peptidase S8 family - - - 0.000000000000002892 90.0
TLS1_k127_3671385_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 434.0
TLS1_k127_3671385_1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 413.0
TLS1_k127_3671385_2 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 319.0
TLS1_k127_3671385_3 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000001351 154.0
TLS1_k127_3671385_4 sequence-specific DNA binding - - - 0.00008495 50.0
TLS1_k127_3691445_0 PFAM ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000005639 98.0
TLS1_k127_3691445_1 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000001964 89.0
TLS1_k127_3691445_3 Voltage gated chloride channel K03281 - - 0.000000003289 63.0
TLS1_k127_3711345_0 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 381.0
TLS1_k127_3711345_1 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 329.0
TLS1_k127_3711345_2 PFAM Fatty acid desaturase, type 2 K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000002803 269.0
TLS1_k127_3711345_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000004543 225.0
TLS1_k127_3711345_4 Major facilitator Superfamily K03291 - - 0.00000000000000000000000000000001709 141.0
TLS1_k127_3711345_5 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000003786 125.0
TLS1_k127_3711345_6 - - - - 0.00002591 50.0
TLS1_k127_3751552_0 belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 321.0
TLS1_k127_3751552_1 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000009638 154.0
TLS1_k127_3751552_2 Activator of Hsp90 ATPase 1 family - - - 0.0000000000000001804 82.0
TLS1_k127_3751552_3 - - - - 0.000000001377 66.0
TLS1_k127_3790679_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 420.0
TLS1_k127_3790679_1 Abc-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000008353 216.0
TLS1_k127_3790679_2 Abc-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000003157 205.0
TLS1_k127_3790679_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000005704 198.0
TLS1_k127_3790679_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000001501 119.0
TLS1_k127_3790679_5 DNA-binding transcription factor activity - - - 0.00000000000000000000005125 102.0
TLS1_k127_3805014_0 His Kinase A (phosphoacceptor) domain K07654 - 2.7.13.3 0.000000000000000000000001012 116.0
TLS1_k127_3805014_1 Tetratrico peptide repeat - - - 0.000000000000000007751 87.0
TLS1_k127_3805014_2 Protein of unknown function (DUF1761) - - - 0.00000003319 61.0
TLS1_k127_3806389_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 525.0
TLS1_k127_3806389_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000003248 117.0
TLS1_k127_3806389_2 - - - - 0.00001192 52.0
TLS1_k127_382899_0 COGs COG0534 Na -driven multidrug efflux pump K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 327.0
TLS1_k127_382899_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000002273 207.0
TLS1_k127_382899_2 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000001348 175.0
TLS1_k127_382899_3 PFAM EamA-like transporter family - - - 0.00000000000000000000000000000000000000002054 164.0
TLS1_k127_382899_4 Major facilitator superfamily - - - 0.00000000000000003384 94.0
TLS1_k127_382899_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00002196 47.0
TLS1_k127_3904646_0 histidinol dehydrogenase activity K15509 - 1.1.1.308 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 456.0
TLS1_k127_3904646_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000003773 132.0
TLS1_k127_3919277_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 538.0
TLS1_k127_3919277_1 E1-E2 ATPase K12952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 410.0
TLS1_k127_3919277_2 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 378.0
TLS1_k127_3919277_3 ANTAR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009392 272.0
TLS1_k127_3919277_4 ANTAR - - - 0.0000000000000000000000000000000000000000006705 167.0
TLS1_k127_3936598_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 517.0
TLS1_k127_3936598_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 306.0
TLS1_k127_3936598_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000008154 108.0
TLS1_k127_3936598_3 Competence-damaged protein K03742 - 3.5.1.42 0.0000000294 56.0
TLS1_k127_3964541_0 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000001405 217.0
TLS1_k127_3964541_1 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.00000000000000000000000000000000000003155 151.0
TLS1_k127_3964541_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000004361 110.0
TLS1_k127_3964541_3 CcmB protein K02194 - - 0.000007653 50.0
TLS1_k127_3966255_0 Peptidase family M1 domain K08776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 330.0
TLS1_k127_3966255_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000006206 169.0
TLS1_k127_3966255_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003714 162.0
TLS1_k127_3966255_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000252 121.0
TLS1_k127_3983429_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000001573 155.0
TLS1_k127_3983429_1 Metallo-peptidase family M12 - - - 0.00000000004264 67.0
TLS1_k127_39983_0 FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 2.84e-207 660.0
TLS1_k127_39983_1 L-arabinose isomerase K01804 - 5.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 470.0
TLS1_k127_39983_2 Pfam Class II Aldolase and Adducin N-terminal domain K03077 - 5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001173 257.0
TLS1_k127_39983_3 Periplasmic binding protein LacI transcriptional regulator - - - 0.0000000000000001579 81.0
TLS1_k127_4003609_0 Hydroxypyruvate reductase K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000001263 175.0
TLS1_k127_4003609_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000006646 60.0
TLS1_k127_4015948_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 6.844e-219 689.0
TLS1_k127_4015948_1 Biotin carboxylase, N-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 547.0
TLS1_k127_4015948_2 Biotin-(Acetyl-CoA carboxylase) ligase K03524 - 6.3.4.15 0.0000000000000000000002871 105.0
TLS1_k127_4015948_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000009706 101.0
TLS1_k127_4047252_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 367.0
TLS1_k127_4047252_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 351.0
TLS1_k127_4047252_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002645 247.0
TLS1_k127_4047252_3 Single-strand binding protein family K03111 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000007262 158.0
TLS1_k127_4047252_4 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000003663 128.0
TLS1_k127_4047252_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000006372 102.0
TLS1_k127_4047252_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000001267 100.0
TLS1_k127_4047252_7 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000009194 74.0
TLS1_k127_4059392_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 309.0
TLS1_k127_4059392_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004635 271.0
TLS1_k127_4059392_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003693 260.0
TLS1_k127_4059392_3 - K01992 - - 0.0000000000000000000000007763 121.0
TLS1_k127_4059392_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000002722 104.0
TLS1_k127_4059392_5 phosphatase activity K05967 - - 0.00000000003861 64.0
TLS1_k127_4059392_6 HAD-hyrolase-like - - - 0.000000007035 57.0
TLS1_k127_4061145_0 Dehydrogenase K00004,K00060,K08322 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0030246,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 1.1.1.103,1.1.1.303,1.1.1.380,1.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 524.0
TLS1_k127_4061145_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001703 280.0
TLS1_k127_4061145_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000009863 216.0
TLS1_k127_4061145_3 hydrolase - - - 0.00000000000000000000000000000000000000000000000000000001273 207.0
TLS1_k127_4061145_4 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000001794 211.0
TLS1_k127_4061145_5 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000135 179.0
TLS1_k127_4061145_6 SMART ATP-binding region ATPase domain protein K03320 - - 0.0000000000000000000000000000000000003085 153.0
TLS1_k127_4061145_7 NAD(P)H-binding K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000104 132.0
TLS1_k127_4061145_8 - - - - 0.00000000000000000000000000000001957 130.0
TLS1_k127_4061184_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 571.0
TLS1_k127_4061184_1 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 471.0
TLS1_k127_4061184_10 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0009008 48.0
TLS1_k127_4061184_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001843 244.0
TLS1_k127_4061184_3 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000006432 231.0
TLS1_k127_4061184_4 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000001482 221.0
TLS1_k127_4061184_5 - - - - 0.000000000000000000000000000000000000000000004189 187.0
TLS1_k127_4061184_6 Phage shock protein A, PspA K03969 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000174 145.0
TLS1_k127_4061184_7 - - - - 0.000000000000004399 76.0
TLS1_k127_4061184_8 Domain of unknown function (DUF4287) - - - 0.0000000001744 63.0
TLS1_k127_4061184_9 - - - - 0.00000113 52.0
TLS1_k127_4064307_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 2.13e-262 831.0
TLS1_k127_4066076_0 Belongs to the peptidase S8 family - - - 3.086e-276 874.0
TLS1_k127_4066076_1 - - - - 0.000000000000001118 83.0
TLS1_k127_4070291_0 Alpha amylase catalytic K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 608.0
TLS1_k127_4070291_1 Binding-protein-dependent transport system inner membrane component K10234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 337.0
TLS1_k127_4070291_2 COG1175 ABC-type sugar transport systems permease components K10233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 313.0
TLS1_k127_4070291_3 ABC-type sugar transport system periplasmic component K10232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 298.0
TLS1_k127_4070291_4 Domain of unknown function (DUF4032) - - - 0.00000000000000000002979 94.0
TLS1_k127_4083475_0 AMP-binding enzyme C-terminal domain K02182,K20034 GO:0003674,GO:0003824,GO:0003996,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044464,GO:0071704 6.2.1.44,6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000001064 231.0
TLS1_k127_4083475_1 Predicted membrane protein (DUF2306) - - - 0.0000000000000000000000000000000000000000000000000000008092 198.0
TLS1_k127_4083475_2 Bacterial PH domain - - - 0.000000000000000000000000000000000001824 145.0
TLS1_k127_4086756_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 587.0
TLS1_k127_4086756_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000004877 156.0
TLS1_k127_4093928_0 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 379.0
TLS1_k127_4093928_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 343.0
TLS1_k127_4093928_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002513 281.0
TLS1_k127_4093928_3 ABC transporter, periplasmic binding protein, thiB subfamily K02064 - - 0.0000000000000000000000000000000000000000000002187 174.0
TLS1_k127_4100597_0 Sporulation and spore germination - - - 0.00000000000000000000000000000000000000000000000000000000005298 216.0
TLS1_k127_4109411_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 311.0
TLS1_k127_4109411_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000008714 149.0
TLS1_k127_4109411_2 - - - - 0.0000000000000000005327 95.0
TLS1_k127_4110222_0 Dihydropyrimidinase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 494.0
TLS1_k127_4110222_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 483.0
TLS1_k127_4110222_2 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 404.0
TLS1_k127_4110222_3 inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000002942 213.0
TLS1_k127_4110222_4 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.00000000000000000000000000005184 117.0
TLS1_k127_4122744_0 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000002776 159.0
TLS1_k127_4122744_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000004457 155.0
TLS1_k127_4122744_2 merR family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000001804 116.0
TLS1_k127_4122744_3 FHA domain protein - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.0000000000000000000000009359 110.0
TLS1_k127_4122744_4 PFAM extracellular solute-binding protein, family 5 - - - 0.0000000000000000004173 92.0
TLS1_k127_4126591_0 Peptidase family M41 - - - 0.0000000000000000000000001559 113.0
TLS1_k127_4126591_1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000057 66.0
TLS1_k127_4126591_2 alpha/beta hydrolase fold - - - 0.0000489 46.0
TLS1_k127_4131486_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 425.0
TLS1_k127_4131486_1 Trypsin-like peptidase domain K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 402.0
TLS1_k127_413227_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00004205 56.0
TLS1_k127_4135548_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 393.0
TLS1_k127_4135548_1 LVIVD repeat - - - 0.000000000000000000000000000000000000000000007183 175.0
TLS1_k127_4135548_2 dipeptide transport K02035 - - 0.00000000000000000000000000001296 136.0
TLS1_k127_4135548_3 PAS fold K18350 - 2.7.13.3 0.000000000000000000006664 108.0
TLS1_k127_4135548_4 - - - - 0.0000000000000000002932 94.0
TLS1_k127_4139365_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.4.4.2 0.0 1240.0
TLS1_k127_4139365_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 443.0
TLS1_k127_4139365_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000002073 212.0
TLS1_k127_4141936_0 AMP-binding enzyme C-terminal domain K01897,K18660 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 557.0
TLS1_k127_4141936_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 449.0
TLS1_k127_4141936_2 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 415.0
TLS1_k127_4141936_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 380.0
TLS1_k127_4141936_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000001921 171.0
TLS1_k127_4141936_5 SnoaL-like polyketide cyclase - - - 0.000000000000000536 83.0
TLS1_k127_4144569_0 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000009853 161.0
TLS1_k127_4144569_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000006105 155.0
TLS1_k127_4144569_2 CarD family transcriptional regulator K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000129 141.0
TLS1_k127_4148631_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00135,K00138,K00146 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 509.0
TLS1_k127_4148631_1 KR domain K00038 - 1.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000008842 240.0
TLS1_k127_4148631_2 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000001029 200.0
TLS1_k127_4148631_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000001325 91.0
TLS1_k127_4151784_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 590.0
TLS1_k127_4151784_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000002757 137.0
TLS1_k127_4159621_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.748e-301 933.0
TLS1_k127_4159621_1 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 347.0
TLS1_k127_4160875_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 371.0
TLS1_k127_4160875_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0008150,GO:0040007 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 316.0
TLS1_k127_4176911_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 422.0
TLS1_k127_4176911_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000425 83.0
TLS1_k127_4178483_0 PFAM Cys Met metabolism pyridoxal-phosphate- dependent protein K01739,K01758,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 423.0
TLS1_k127_4178483_1 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000005662 212.0
TLS1_k127_4178483_2 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000001343 209.0
TLS1_k127_4178483_3 Acyl-CoA dehydrogenase, middle domain K08297,K20035 - 1.3.8.13 0.000000000000000000000000000000000000000001658 158.0
TLS1_k127_4179526_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 522.0
TLS1_k127_4179526_1 Fe-S oxidoreductase K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001222 256.0
TLS1_k127_4179526_2 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.000000000000000000000000000000000000000000004942 179.0
TLS1_k127_4179526_3 Protein of unknown function (DUF559) - - - 0.0001225 52.0
TLS1_k127_4179765_0 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 384.0
TLS1_k127_4179765_1 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006656 253.0
TLS1_k127_4179765_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000001036 245.0
TLS1_k127_4194345_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02827 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.10.3.12,1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 609.0
TLS1_k127_4194345_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 355.0
TLS1_k127_4194345_10 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000004467 98.0
TLS1_k127_4194345_11 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000001759 59.0
TLS1_k127_4194345_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 312.0
TLS1_k127_4194345_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002501 292.0
TLS1_k127_4194345_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000005614 262.0
TLS1_k127_4194345_5 Cytochrome c oxidase subunit III K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000009907 208.0
TLS1_k127_4194345_6 - - - - 0.000000000000000000000000000000000000000000000000000000002049 214.0
TLS1_k127_4194345_7 Sodium:sulfate symporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000009139 198.0
TLS1_k127_4194345_8 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02862 - - 0.00000000000000000000000000000000000000000000000000009731 197.0
TLS1_k127_4194345_9 cell redox homeostasis K02199 - - 0.00000000000000000000000002694 121.0
TLS1_k127_4195970_0 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 304.0
TLS1_k127_4195970_1 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000007407 75.0
TLS1_k127_4207704_0 permease K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 417.0
TLS1_k127_4207704_1 TIGRFAM purine nucleoside phosphorylase K03784 GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003787 262.0
TLS1_k127_4207704_2 - - - - 0.000000000000002413 86.0
TLS1_k127_4222925_0 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 402.0
TLS1_k127_4222925_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000001168 179.0
TLS1_k127_4227161_0 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000006473 180.0
TLS1_k127_4227161_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000002814 144.0
TLS1_k127_4227161_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000002402 126.0
TLS1_k127_4227161_3 Alpha/beta hydrolase family K07020 - - 0.0000000000000000000000000006956 118.0
TLS1_k127_4227254_0 protein conserved in bacteria K09955 - - 3.528e-272 850.0
TLS1_k127_4227254_1 alcohol dehydrogenase K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000006711 249.0
TLS1_k127_4227254_2 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000007597 193.0
TLS1_k127_4241065_0 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.00000000000000000000000000000002413 138.0
TLS1_k127_4241065_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000001169 106.0
TLS1_k127_4255622_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 458.0
TLS1_k127_4255622_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002033 278.0
TLS1_k127_4255622_2 histidinol dehydrogenase activity K14152 - 1.1.1.23,3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000003947 162.0
TLS1_k127_4255622_3 Glutamine amidotransferase class-I K02501 - - 0.0000000000000000000000000000000003848 135.0
TLS1_k127_4281524_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.921e-298 936.0
TLS1_k127_4281524_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 340.0
TLS1_k127_4281524_2 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001316 280.0
TLS1_k127_4281524_3 Helix-hairpin-helix motif K02237 - - 0.0000000000000000000000000000000007599 138.0
TLS1_k127_4298554_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0 1311.0
TLS1_k127_4298554_1 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 478.0
TLS1_k127_4298554_2 DegT/DnrJ/EryC1/StrS aminotransferase family - GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008483,GO:0010326,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 434.0
TLS1_k127_4298554_3 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 359.0
TLS1_k127_4298554_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000203 263.0
TLS1_k127_4298554_5 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009727 251.0
TLS1_k127_4298554_6 deazaflavin-dependent nitroreductase family protein - - - 0.00000000000000000000000000000001101 132.0
TLS1_k127_4298554_7 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000004835 104.0
TLS1_k127_4298554_8 Universal stress protein - - - 0.0000000000000009194 83.0
TLS1_k127_4298554_9 TfoX N-terminal domain - - - 0.0000000008955 64.0
TLS1_k127_430196_0 amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000009434 233.0
TLS1_k127_430196_1 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000005107 225.0
TLS1_k127_430196_2 PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.00000000000000000000000000000000000000002704 156.0
TLS1_k127_4304945_0 Cytosol aminopeptidase family, catalytic domain K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 545.0
TLS1_k127_4304945_1 transporter K12942 - - 0.00000000000000000000000000000000000000000000000000347 191.0
TLS1_k127_43102_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 372.0
TLS1_k127_43102_1 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000004626 194.0
TLS1_k127_43102_2 amino acid - - - 0.00001608 50.0
TLS1_k127_4314552_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 475.0
TLS1_k127_4314552_1 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 368.0
TLS1_k127_4314552_2 - - - - 0.00000000000000000000000000000000000000000000000000000000004561 218.0
TLS1_k127_4314552_3 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000278 179.0
TLS1_k127_4314552_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000002497 131.0
TLS1_k127_4314552_5 solute carrier family 22 - - - 0.000000000000000000000005214 109.0
TLS1_k127_4351373_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 1.995e-281 881.0
TLS1_k127_4351373_1 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 359.0
TLS1_k127_4351373_2 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 308.0
TLS1_k127_4351373_3 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001418 250.0
TLS1_k127_4351373_4 Sigma associated protein - - - 0.0000000000000000000000000000000000000006678 151.0
TLS1_k127_4351373_5 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000001572 124.0
TLS1_k127_4351373_6 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.0000000000000000000000000000006947 125.0
TLS1_k127_4357810_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 8.254e-292 940.0
TLS1_k127_4357810_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 537.0
TLS1_k127_4357810_10 Peptidylprolyl isomerase K01802,K03769 - 5.2.1.8 0.00000000000000000000003926 110.0
TLS1_k127_4357810_11 Septum formation initiator - - - 0.00000009388 63.0
TLS1_k127_4357810_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 389.0
TLS1_k127_4357810_3 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 356.0
TLS1_k127_4357810_4 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 321.0
TLS1_k127_4357810_5 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 316.0
TLS1_k127_4357810_6 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000005912 207.0
TLS1_k127_4357810_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000003263 138.0
TLS1_k127_4357810_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000001119 113.0
TLS1_k127_4357810_9 Protein of unknown function (DUF501) K09009 - - 0.000000000000000000000000002847 124.0
TLS1_k127_4362671_0 B12 binding domain K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 451.0
TLS1_k127_4362671_1 Homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 314.0
TLS1_k127_4362671_2 PFAM glycoside hydrolase family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000003981 123.0
TLS1_k127_4368081_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 437.0
TLS1_k127_4368081_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 323.0
TLS1_k127_4368081_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000007837 63.0
TLS1_k127_4377667_0 Flavin containing amine oxidoreductase - - - 1.799e-250 782.0
TLS1_k127_4377667_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000007625 242.0
TLS1_k127_4377667_2 PFAM SMP-30 Gluconolaconase K14274 - - 0.000000000000000000000000000000000000000000000000000000009254 209.0
TLS1_k127_4377667_3 PFAM EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000537 190.0
TLS1_k127_4377667_4 CGNR zinc finger - - - 0.0000000000000000000000000000009649 128.0
TLS1_k127_4377667_5 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000002577 109.0
TLS1_k127_4377667_7 membrane K08972 - - 0.00000000000002181 80.0
TLS1_k127_4380560_0 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000002655 246.0
TLS1_k127_4380560_1 - - - - 0.000000000000000000671 94.0
TLS1_k127_4380560_2 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor - - - 0.00000000003253 73.0
TLS1_k127_4395738_0 AI-2E family transporter - - - 0.0000000000000000000000000000000000008968 154.0
TLS1_k127_4399798_0 4-hydroxybenzoate K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 474.0
TLS1_k127_4399798_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 394.0
TLS1_k127_4399798_2 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 349.0
TLS1_k127_4399798_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006118 276.0
TLS1_k127_4405382_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 363.0
TLS1_k127_4405382_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 293.0
TLS1_k127_4405382_2 LysE type translocator - - - 0.000000000000000000000000000000000000000000000748 175.0
TLS1_k127_4405382_3 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000007283 143.0
TLS1_k127_4417088_0 belongs to the aldehyde dehydrogenase family K00130,K00151 - 1.2.1.60,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 293.0
TLS1_k127_4417088_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000004363 179.0
TLS1_k127_4417088_2 transcriptional regulator - - - 0.00000000000000000000000000000000000004351 149.0
TLS1_k127_4434546_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 3.269e-233 738.0
TLS1_k127_4434546_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 503.0
TLS1_k127_4434546_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000012 255.0
TLS1_k127_4434546_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000001024 60.0
TLS1_k127_4434546_4 Protein of unknown function (DUF721) - - - 0.00001529 52.0
TLS1_k127_4508440_0 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 438.0
TLS1_k127_4508440_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000006252 117.0
TLS1_k127_4508440_2 PAS fold - - - 0.0000000000000000000001774 113.0
TLS1_k127_4508440_3 - - - - 0.000000000000000000001144 109.0
TLS1_k127_4508440_4 Bacterial low temperature requirement A protein (LtrA) - - - 0.000000000000000000002863 96.0
TLS1_k127_4552173_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 384.0
TLS1_k127_4552173_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 337.0
TLS1_k127_4552173_2 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000422 280.0
TLS1_k127_4552173_3 - - - - 0.000000000000000000000000000000000004674 144.0
TLS1_k127_4556266_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 515.0
TLS1_k127_4556266_1 Alkylmercury lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 322.0
TLS1_k127_4556266_2 HNH endonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000001503 170.0
TLS1_k127_4556266_3 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000007587 125.0
TLS1_k127_4556266_4 F420H(2)-dependent quinone reductase - - - 0.00000000007817 71.0
TLS1_k127_4584163_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 388.0
TLS1_k127_4584163_1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000004235 201.0
TLS1_k127_4584163_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K01924,K02563 - 2.4.1.227,6.3.2.8 0.00000000000000000000000000000000000000000000000001146 196.0
TLS1_k127_4584163_3 Cell cycle protein K03588 - - 0.000000000000000001319 87.0
TLS1_k127_4587330_0 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 344.0
TLS1_k127_4587330_1 ABC-type sugar transport system, permease component K02026,K10119,K17243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000162 280.0
TLS1_k127_4719982_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000001411 213.0
TLS1_k127_4719982_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000009792 149.0
TLS1_k127_4719982_2 Ferric reductase like transmembrane component - - - 0.0000000000000000000001547 105.0
TLS1_k127_4719982_3 Evidence 5 No homology to any previously reported sequences - - - 0.0003837 51.0
TLS1_k127_4728166_0 Major Facilitator Superfamily - - - 3.966e-225 711.0
TLS1_k127_4728166_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 355.0
TLS1_k127_4728166_2 - - - - 0.00000000000003332 78.0
TLS1_k127_4780796_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 475.0
TLS1_k127_4780796_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 318.0
TLS1_k127_478333_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 293.0
TLS1_k127_478333_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001219 237.0
TLS1_k127_4788164_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 2.988e-256 803.0
TLS1_k127_4788164_1 L,D-transpeptidase catalytic domain - - - 0.0000362 55.0
TLS1_k127_4796698_0 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 299.0
TLS1_k127_4796698_1 - - - - 0.00000000000000000003912 96.0
TLS1_k127_4821764_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 477.0
TLS1_k127_4821764_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 331.0
TLS1_k127_4821764_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 301.0
TLS1_k127_4821764_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000913 100.0
TLS1_k127_4821764_4 Cysteine-rich secretory protein family - - - 0.0000000000001428 77.0
TLS1_k127_4821764_5 - - - - 0.00000002755 64.0
TLS1_k127_483519_0 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 383.0
TLS1_k127_483519_1 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 352.0
TLS1_k127_483519_2 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003904 283.0
TLS1_k127_483519_3 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006232 250.0
TLS1_k127_483519_4 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000003176 198.0
TLS1_k127_483519_5 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000009991 166.0
TLS1_k127_483519_6 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000001493 158.0
TLS1_k127_483519_7 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000006916 125.0
TLS1_k127_4836_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 2851.0
TLS1_k127_4836_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 394.0
TLS1_k127_4836_2 - - - - 0.000000000000000000000000003539 113.0
TLS1_k127_4836_3 Sporulation and spore germination - - - 0.0000000000000000000001415 110.0
TLS1_k127_4836_4 - - - - 0.00002937 50.0
TLS1_k127_4839038_0 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 315.0
TLS1_k127_4839038_1 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000002174 225.0
TLS1_k127_4839038_2 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000007477 199.0
TLS1_k127_4839038_3 Oxidoreductase family, C-terminal alpha/beta domain K19181 - 1.1.1.292 0.0000000000000000000000000000000000000000000000009422 187.0
TLS1_k127_4839038_4 Mannose-6-phosphate isomerase - - - 0.000003043 49.0
TLS1_k127_4858822_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K02351,K07245,K21071 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 352.0
TLS1_k127_4858822_1 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000001764 183.0
TLS1_k127_4858822_2 Beta-lactamase enzyme family - - - 0.000000000000000000000000007652 120.0
TLS1_k127_4858822_3 Universal stress protein family - - - 0.0000000000001691 78.0
TLS1_k127_4858822_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000004605 66.0
TLS1_k127_4863644_0 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000000000000000000000002806 192.0
TLS1_k127_4863644_2 Copper binding proteins, plastocyanin/azurin family - - - 0.000002466 57.0
TLS1_k127_4887171_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000004397 226.0
TLS1_k127_4887171_2 Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system K02013,K21480 - 1.14.15.20,3.6.3.34 0.000000000000000000000000000000000000000000000000000000006803 208.0
TLS1_k127_4887171_3 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000005549 207.0
TLS1_k127_4887171_4 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000003345 148.0
TLS1_k127_4893488_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000001374 175.0
TLS1_k127_4893488_1 Zincin-like metallopeptidase - - - 0.000000000000000004662 95.0
TLS1_k127_4895396_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 284.0
TLS1_k127_4895396_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000299 202.0
TLS1_k127_4895396_2 Acetyltransferase (GNAT) domain K17840 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0034069,GO:0044237,GO:0044248,GO:0044464,GO:0047921,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 2.3.1.59 0.0000000000000000000000000000000000000002785 156.0
TLS1_k127_4909464_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 417.0
TLS1_k127_4909464_1 Transmembrane domain of unknown function (DUF3566) - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00002358 49.0
TLS1_k127_4928316_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 414.0
TLS1_k127_4928316_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008289,GO:0009405,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0030312,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0043177,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0051704,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204 2.3.1.61 0.00000000000000000000004906 102.0
TLS1_k127_4928316_2 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000002668 103.0
TLS1_k127_4983535_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 9.027e-249 782.0
TLS1_k127_4983535_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 437.0
TLS1_k127_4983535_2 Oxidoreductase FAD-binding domain K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 373.0
TLS1_k127_4983535_3 Iron-sulfur cluster assembly protein K02612 - - 0.000000000000000000000000000000000000000000000000009765 186.0
TLS1_k127_4983535_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000001541 153.0
TLS1_k127_4983535_5 - - - - 0.00000000000000000000000000000000001409 156.0
TLS1_k127_4983535_6 Belongs to the peptidase S8 family - - - 0.00000000000005688 86.0
TLS1_k127_4983535_7 Phenylacetate-CoA oxygenase K02611 - 1.14.13.149 0.000000000001679 67.0
TLS1_k127_4983535_8 N-acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000000003059 74.0
TLS1_k127_504238_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 472.0
TLS1_k127_504238_1 Selenocysteine lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 445.0
TLS1_k127_504238_10 Ferric uptake regulator family K03711,K09825 - - 0.00000000000000000000000002998 113.0
TLS1_k127_504238_2 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 397.0
TLS1_k127_504238_3 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 363.0
TLS1_k127_504238_4 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 352.0
TLS1_k127_504238_5 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002517 279.0
TLS1_k127_504238_6 Cobalt ABC transporter K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007925 259.0
TLS1_k127_504238_7 retinol dehydrogenase K11153,K11161 - 1.1.1.300 0.00000000000000000000000000000000000000000000002355 183.0
TLS1_k127_504238_8 Endoribonuclease L-PSP - - - 0.000000000000000000000000000001705 126.0
TLS1_k127_504238_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000005283 121.0
TLS1_k127_5057954_0 (ABC) transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 379.0
TLS1_k127_5057954_1 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000463 94.0
TLS1_k127_5061009_0 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000000009414 132.0
TLS1_k127_5061009_1 Domain of unknown function (DUF4118) - - - 0.0004135 46.0
TLS1_k127_5063844_0 Capsular exopolysaccharide family - - - 0.0003375 53.0
TLS1_k127_5063939_0 PFAM polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002097 287.0
TLS1_k127_5063939_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000008633 253.0
TLS1_k127_5063939_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000001261 222.0
TLS1_k127_5063939_3 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000004669 153.0
TLS1_k127_5063939_4 -O-antigen - - - 0.00000000000000000001486 107.0
TLS1_k127_5063939_5 Belongs to the peptidase S8 family - - - 0.0000000000000000455 95.0
TLS1_k127_5063939_6 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.00001502 55.0
TLS1_k127_5063939_7 peptidoglycan turnover - - - 0.00001842 55.0
TLS1_k127_5073572_0 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001414 293.0
TLS1_k127_5073572_1 Extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000001854 130.0
TLS1_k127_5073572_2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone - - - 0.000000000000000000000000000001636 121.0
TLS1_k127_5088014_0 ABC 3 transport family K02075,K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 298.0
TLS1_k127_5088014_1 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000167 232.0
TLS1_k127_5088014_2 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000003521 124.0
TLS1_k127_5088014_3 Ferric uptake regulator family K03711 - - 0.00000000000000000000000005189 112.0
TLS1_k127_5088014_4 AAA domain, putative AbiEii toxin, Type IV TA system K02013 - 3.6.3.34 0.00000000000000001789 91.0
TLS1_k127_5088136_0 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 339.0
TLS1_k127_5088136_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 0.0000000000000000000000000004312 121.0
TLS1_k127_5091251_0 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 336.0
TLS1_k127_5091251_1 beta-1,4-mannooligosaccharide phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004474 260.0
TLS1_k127_5091251_2 Imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000005961 252.0
TLS1_k127_5091251_3 histidinol-phosphate transaminase activity K00817,K01814 GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0010038,GO:0010045,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000003106 256.0
TLS1_k127_5091251_4 Glutamine amidotransferase class-I K02501 - - 0.0000000000000000002179 99.0
TLS1_k127_5100187_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 440.0
TLS1_k127_5100187_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000001218 242.0
TLS1_k127_5100187_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000001207 109.0
TLS1_k127_5100187_3 Type IV leader peptidase family K02654 - 3.4.23.43 0.000000000000000002182 94.0
TLS1_k127_5101676_0 Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta - - - 2.107e-234 736.0
TLS1_k127_5101676_1 Belongs to the thiolase family K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 464.0
TLS1_k127_5101676_10 Domain of unknown function (DUF4388) - - - 0.0000448 54.0
TLS1_k127_5101676_2 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002364 265.0
TLS1_k127_5101676_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000006895 214.0
TLS1_k127_5101676_4 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000007361 214.0
TLS1_k127_5101676_5 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000001956 209.0
TLS1_k127_5101676_6 HhH-GPD superfamily base excision DNA repair protein - - - 0.0000000000000000000000000000000000000000000000000003624 190.0
TLS1_k127_5101676_7 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000005045 187.0
TLS1_k127_5101676_8 PFAM Uncharacterised protein family UPF0047 - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000002376 108.0
TLS1_k127_5101676_9 - - - - 0.0000000000008787 74.0
TLS1_k127_5102315_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 490.0
TLS1_k127_5102315_1 Insulinase (Peptidase family M16) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 404.0
TLS1_k127_5102315_2 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 305.0
TLS1_k127_5102315_3 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000002062 233.0
TLS1_k127_5102315_4 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000003413 199.0
TLS1_k127_5102315_5 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000001093 190.0
TLS1_k127_5102315_6 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000012 162.0
TLS1_k127_5102315_7 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000003601 62.0
TLS1_k127_5110535_0 Class II release factor RF3, C-terminal domain K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 605.0
TLS1_k127_5110535_1 Transcriptional regulator - - - 0.0000000000000855 74.0
TLS1_k127_5110890_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 537.0
TLS1_k127_5110890_1 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 460.0
TLS1_k127_5110890_2 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000001607 119.0
TLS1_k127_5116166_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000009543 217.0
TLS1_k127_5116166_1 COG0662 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000001616 184.0
TLS1_k127_5116166_2 Endoribonuclease L-PSP - - - 0.00000000000000000000009216 104.0
TLS1_k127_5116166_3 - - - - 0.0000000000000000883 85.0
TLS1_k127_5116166_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000002918 70.0
TLS1_k127_5121643_0 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 488.0
TLS1_k127_5121643_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 360.0
TLS1_k127_5121643_2 Glycerol acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 334.0
TLS1_k127_5121643_3 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005107 284.0
TLS1_k127_5121643_4 ATPases associated with a variety of cellular activities K10112 - - 0.000000000000000000000000000000000003046 143.0
TLS1_k127_5121643_5 SnoaL-like domain - - - 0.00000000000000000000000003473 117.0
TLS1_k127_512741_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 359.0
TLS1_k127_512741_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000507 280.0
TLS1_k127_512741_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000006181 234.0
TLS1_k127_512741_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000182 187.0
TLS1_k127_512741_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000379 188.0
TLS1_k127_512741_5 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000103 153.0
TLS1_k127_512741_6 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000457 72.0
TLS1_k127_512741_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000001759 63.0
TLS1_k127_5153598_0 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 616.0
TLS1_k127_5153598_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003937 286.0
TLS1_k127_5153598_2 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000002762 213.0
TLS1_k127_5153598_3 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000001122 150.0
TLS1_k127_5153598_4 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000001502 85.0
TLS1_k127_5153598_5 Metallo-beta-lactamase superfamily - - - 0.000000000003366 69.0
TLS1_k127_5158868_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0005575,GO:0005576,GO:0008150,GO:0040007 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 535.0
TLS1_k127_5158868_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 529.0
TLS1_k127_5158868_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000007573 130.0
TLS1_k127_5158868_11 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000008252 125.0
TLS1_k127_5158868_12 structural constituent of ribosome K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000002053 74.0
TLS1_k127_5158868_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 402.0
TLS1_k127_5158868_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 351.0
TLS1_k127_5158868_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000003813 267.0
TLS1_k127_5158868_5 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000008903 234.0
TLS1_k127_5158868_6 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000000000005153 201.0
TLS1_k127_5158868_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000005693 196.0
TLS1_k127_5158868_8 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000000000006669 175.0
TLS1_k127_5158868_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000002705 154.0
TLS1_k127_5159959_0 Belongs to the peptidase S1B family K04775 - - 0.0000000000000000000000000000000000000000000000000000000000001068 232.0
TLS1_k127_5159959_1 TIR domain - - - 0.000000000000000000000000000000000000869 152.0
TLS1_k127_5159959_2 Putative peptidoglycan binding domain - - - 0.0000000002588 70.0
TLS1_k127_5159959_3 Belongs to the peptidase S8 family - - - 0.0000005619 53.0
TLS1_k127_5164582_0 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 383.0
TLS1_k127_5164582_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000217 282.0
TLS1_k127_5164582_2 Mandelate racemase muconate lactonizing enzyme K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000001258 238.0
TLS1_k127_5164582_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000002018 234.0
TLS1_k127_5164582_4 Belongs to the mandelate racemase muconate lactonizing enzyme family K01856 - 5.5.1.1 0.00000000000000000000000000000004301 136.0
TLS1_k127_5164582_5 - - - - 0.000004239 55.0
TLS1_k127_5167051_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000445 212.0
TLS1_k127_5167051_1 - - - - 0.0000000000000000000000000000000000000006321 153.0
TLS1_k127_5167051_2 Ion channel - - - 0.0000000000000000001601 91.0
TLS1_k127_5167051_3 HNH nucleases - - - 0.00000000006109 64.0
TLS1_k127_5167089_0 Glycosyl hydrolases family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 370.0
TLS1_k127_5167089_1 CoA binding domain - - - 0.000000000000000000000000000000000000001916 156.0
TLS1_k127_5167089_2 HNH nucleases - - - 0.000000000009499 67.0
TLS1_k127_5167309_0 NADPH:quinone reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 273.0
TLS1_k127_5167309_1 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000002175 161.0
TLS1_k127_5167309_2 AI-2E family transporter - - - 0.00000000000000000000000000000001105 131.0
TLS1_k127_5167309_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000002576 74.0
TLS1_k127_5170837_0 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 616.0
TLS1_k127_5170837_1 ABC transporter, transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 482.0
TLS1_k127_5170837_2 ABC transporter transmembrane region K02021,K06147,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 466.0
TLS1_k127_5174410_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.391e-209 669.0
TLS1_k127_5174410_1 Displays ATPase and GTPase activities K06958 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 287.0
TLS1_k127_5174410_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000003257 212.0
TLS1_k127_5174410_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000002933 83.0
TLS1_k127_5182554_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 505.0
TLS1_k127_5182554_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 394.0
TLS1_k127_5182554_2 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 321.0
TLS1_k127_5182554_3 CoA-binding domain protein K06929 - - 0.00000000000000000000000008117 114.0
TLS1_k127_5185812_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 304.0
TLS1_k127_5185812_1 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.00000000002721 71.0
TLS1_k127_5199747_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 363.0
TLS1_k127_5199747_1 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 317.0
TLS1_k127_5199747_2 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004594 276.0
TLS1_k127_5199747_3 COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000004718 149.0
TLS1_k127_5199747_4 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000001655 128.0
TLS1_k127_5201539_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 538.0
TLS1_k127_5201539_1 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000582 289.0
TLS1_k127_5207340_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001612 277.0
TLS1_k127_5207340_1 Fasciclin - GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043207,GO:0044403,GO:0044419,GO:0044421,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.00000000000000000000000000000000007899 141.0
TLS1_k127_5207340_2 Histidine kinase - - - 0.00000000000000000000003806 109.0
TLS1_k127_5210964_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004046 286.0
TLS1_k127_5210964_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008937 265.0
TLS1_k127_5214404_0 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000232 295.0
TLS1_k127_5215400_0 Phosphoenolpyruvate carboxylase K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 628.0
TLS1_k127_5215400_1 SMART von Willebrand factor, type A K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000005421 236.0
TLS1_k127_5215400_2 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000001535 195.0
TLS1_k127_5215400_3 XdhC and CoxI family - - - 0.0000000000000000000000000000002062 126.0
TLS1_k127_5220731_0 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 293.0
TLS1_k127_5220731_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001146 295.0
TLS1_k127_5220731_2 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000003802 207.0
TLS1_k127_5220731_3 Pfam:Pyridox_oxidase - - - 0.000000000000000000000001045 110.0
TLS1_k127_5220731_4 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.0000000000000000000002358 103.0
TLS1_k127_5242641_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 408.0
TLS1_k127_5242641_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000005088 128.0
TLS1_k127_5243159_0 DEAD/H associated K03724 - - 0.0 1228.0
TLS1_k127_5243159_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003488 230.0
TLS1_k127_5247407_0 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000003651 247.0
TLS1_k127_5247407_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000004027 202.0
TLS1_k127_5247407_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000003533 115.0
TLS1_k127_5260007_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 546.0
TLS1_k127_5260007_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000001825 176.0
TLS1_k127_5262798_0 Periplasmic binding protein domain K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 386.0
TLS1_k127_5262798_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 334.0
TLS1_k127_5262798_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001126 289.0
TLS1_k127_5262798_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005306 270.0
TLS1_k127_5287419_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1113.0
TLS1_k127_5302108_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.959e-293 912.0
TLS1_k127_5302108_1 Domain of unknown function (DUF3536) - - - 3.321e-194 621.0
TLS1_k127_5302108_10 Putative Flp pilus-assembly TadE/G-like - - - 0.0005554 52.0
TLS1_k127_5302108_2 5'-nucleotidase, C-terminal domain K01081,K01119 - 3.1.3.5,3.1.3.6,3.1.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 504.0
TLS1_k127_5302108_3 signal peptide processing K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 336.0
TLS1_k127_5302108_4 Glycosyl Transferase - - - 0.0000000000000000000000000000000000000000000000000000000002014 214.0
TLS1_k127_5302108_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000005217 209.0
TLS1_k127_5302108_6 - - - - 0.000000000000000000000000000000000000008357 153.0
TLS1_k127_5302108_7 sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000003368 146.0
TLS1_k127_5302108_8 PFAM TadE family protein - - - 0.0000007266 57.0
TLS1_k127_5327947_0 RecF/RecN/SMC N terminal domain K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 601.0
TLS1_k127_5327947_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 401.0
TLS1_k127_5327947_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 294.0
TLS1_k127_5327947_3 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000005507 221.0
TLS1_k127_5327947_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000002654 128.0
TLS1_k127_5327947_5 cytidine and deoxycytidylate deaminase K01489 - 3.5.4.5 0.000000000000000000000000002988 115.0
TLS1_k127_5327947_6 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000001814 92.0
TLS1_k127_5327947_7 Pfam:Pyridox_oxidase K07005 - - 0.000001308 57.0
TLS1_k127_5338443_0 endonuclease exonuclease phosphatase K07004 - - 3.4e-255 820.0
TLS1_k127_5338443_1 Histidine kinase K02484 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0046983,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 0.0000000000001026 79.0
TLS1_k127_5351973_0 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 390.0
TLS1_k127_5351973_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 326.0
TLS1_k127_5355324_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 509.0
TLS1_k127_5355324_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000005604 199.0
TLS1_k127_5355324_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000008716 192.0
TLS1_k127_5355324_3 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.0000000000000000000000000000000000000009011 168.0
TLS1_k127_5360689_0 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007741 266.0
TLS1_k127_5360689_1 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000009164 82.0
TLS1_k127_5372724_0 PFAM sodium calcium exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000007811 203.0
TLS1_k127_5372724_1 LysM domain K03642,K03791,K22278 - 3.5.1.104 0.00000008822 63.0
TLS1_k127_5395063_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 524.0
TLS1_k127_5395063_1 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000007997 82.0
TLS1_k127_5395063_2 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00001921 53.0
TLS1_k127_541230_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.247e-213 671.0
TLS1_k127_541230_1 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000002175 200.0
TLS1_k127_541230_2 - - - - 0.000000000000001555 87.0
TLS1_k127_5423978_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.151e-215 682.0
TLS1_k127_5423978_1 Luciferase-like monooxygenase - - - 8.69e-215 671.0
TLS1_k127_5423978_2 Reductase C-terminal K05297 - 1.18.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 479.0
TLS1_k127_5423978_3 AraC-like ligand binding domain - - - 0.00000000000000000000000000000001792 130.0
TLS1_k127_5423978_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000007082 126.0
TLS1_k127_5423978_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000009089 63.0
TLS1_k127_5431479_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000005267 220.0
TLS1_k127_5431479_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000001359 219.0
TLS1_k127_5431479_2 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000002243 126.0
TLS1_k127_5431479_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000001362 107.0
TLS1_k127_5435112_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 430.0
TLS1_k127_5435112_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000008505 246.0
TLS1_k127_5435112_2 Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000001641 145.0
TLS1_k127_5450493_0 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 432.0
TLS1_k127_5450493_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 409.0
TLS1_k127_5459744_0 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 603.0
TLS1_k127_5459744_1 Acetoacetate decarboxylase (ADC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 370.0
TLS1_k127_5459744_2 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 295.0
TLS1_k127_5459744_3 Peptidase M28 - - - 0.0006424 50.0
TLS1_k127_5466234_0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000001199 258.0
TLS1_k127_5466234_1 PFAM Ribose galactose isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000367 175.0
TLS1_k127_5482570_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 1.946e-222 720.0
TLS1_k127_5482760_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 518.0
TLS1_k127_5482760_1 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000005531 112.0
TLS1_k127_5500335_0 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 438.0
TLS1_k127_5500335_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 419.0
TLS1_k127_5500335_2 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000002008 181.0
TLS1_k127_5500335_3 cheY-homologous receiver domain - - - 0.00000000000000000000002607 104.0
TLS1_k127_5500503_0 carboxylase K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 407.0
TLS1_k127_5500503_1 Protein of unknown function (DUF4230) - - - 0.0000000000000003452 92.0
TLS1_k127_5507852_0 PFAM ABC transporter transmembrane region K06147 - - 6.545e-218 693.0
TLS1_k127_5507852_1 Elongator protein 3 MiaB NifB K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 496.0
TLS1_k127_5507852_2 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 392.0
TLS1_k127_5507852_3 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000003322 234.0
TLS1_k127_5507852_4 DEAD DEAH box K03724 - - 0.0000000000000000000000000000000000000000000000000000000000002752 222.0
TLS1_k127_5507852_5 PFAM Flavin reductase like domain - - - 0.000000000000000000000000009307 115.0
TLS1_k127_5507852_6 Belongs to the universal stress protein A family - - - 0.00002651 53.0
TLS1_k127_552719_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 510.0
TLS1_k127_552719_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008641 268.0
TLS1_k127_552719_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000718 153.0
TLS1_k127_552719_3 - - - - 0.00001725 53.0
TLS1_k127_5528838_0 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 340.0
TLS1_k127_5528838_1 glycerophosphodiester transmembrane transport K02026,K10234 - - 0.00000000000000000000000000000000000000000000001778 172.0
TLS1_k127_5532046_0 Glycosyltransferase K08256 GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000004328 217.0
TLS1_k127_5532046_1 Lipid A biosynthesis K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.000000000000000000000000000000000000000000000009775 186.0
TLS1_k127_5532046_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0005488,GO:0005515,GO:0042802 4.3.3.6 0.0000000000000000000000000000004201 130.0
TLS1_k127_5532046_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000003823 118.0
TLS1_k127_5532046_4 elongation factor g K02355 - - 0.00000003092 56.0
TLS1_k127_5534214_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006416 256.0
TLS1_k127_5534214_1 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.000000000000000000000000000000000000000000002719 171.0
TLS1_k127_5536658_0 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004029 248.0
TLS1_k127_5536658_1 Histidine kinase - - - 0.0000000000000000000000000000000001023 152.0
TLS1_k127_5536658_2 Trypsin - - - 0.0000000000000000000000000000000005298 141.0
TLS1_k127_554223_0 Diguanylate cyclase - - - 5.912e-224 718.0
TLS1_k127_554223_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000006668 214.0
TLS1_k127_554223_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000004587 188.0
TLS1_k127_554223_3 PAS fold - - - 0.0000000000000000000000000000000006896 131.0
TLS1_k127_554223_4 Transcriptional regulator - - - 0.00000000000000000000006774 101.0
TLS1_k127_554223_5 Protein of unknown function (DUF3494) K11904 - - 0.00000000000000000001069 99.0
TLS1_k127_5566359_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 368.0
TLS1_k127_5566359_1 PAC2 family - - - 0.000000000000000000000000000000000000000000000000002884 191.0
TLS1_k127_5576964_0 B12 binding domain K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 555.0
TLS1_k127_5576964_1 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000008109 224.0
TLS1_k127_5576964_10 Anti-sigma-K factor rskA - - - 0.0006003 51.0
TLS1_k127_5576964_2 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000001782 169.0
TLS1_k127_5576964_3 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000006116 171.0
TLS1_k127_5576964_4 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000001129 154.0
TLS1_k127_5576964_5 protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000004145 141.0
TLS1_k127_5576964_6 Histidine kinase K07651 - 2.7.13.3 0.000000000000000000000000001553 127.0
TLS1_k127_5576964_7 regulator of chromosome condensation, RCC1 K12287 - - 0.000000001944 70.0
TLS1_k127_5576964_8 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000001411 62.0
TLS1_k127_5576964_9 Yqey-like protein K09117 - - 0.000006552 54.0
TLS1_k127_558470_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 473.0
TLS1_k127_558470_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 359.0
TLS1_k127_558470_2 Chorismate mutase type II K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 341.0
TLS1_k127_558470_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000285 262.0
TLS1_k127_558470_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000008549 231.0
TLS1_k127_558470_5 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000006039 220.0
TLS1_k127_558470_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000001522 177.0
TLS1_k127_558470_7 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.000000000000000000000000000000000000000002413 165.0
TLS1_k127_558470_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000001787 134.0
TLS1_k127_5601623_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 397.0
TLS1_k127_5601623_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 345.0
TLS1_k127_5601623_2 Creatinase/Prolidase N-terminal domain - - - 0.000000000000001242 76.0
TLS1_k127_5601623_3 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000003087 77.0
TLS1_k127_5601623_4 COG3209 Rhs family protein - - - 0.000008002 59.0
TLS1_k127_5617558_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 411.0
TLS1_k127_5617558_1 ECF sigma factor K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000001235 154.0
TLS1_k127_5617558_2 belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000002449 132.0
TLS1_k127_565309_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 466.0
TLS1_k127_565309_1 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 395.0
TLS1_k127_565309_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001114 290.0
TLS1_k127_565309_3 Cupin domain - - - 0.0000000000000000000000000001959 118.0
TLS1_k127_565309_4 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000001194 115.0
TLS1_k127_5661777_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.053e-212 677.0
TLS1_k127_56687_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K19189 - 1.14.13.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 371.0
TLS1_k127_56687_1 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000008617 265.0
TLS1_k127_56687_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002756 267.0
TLS1_k127_56687_3 PFAM alpha beta hydrolase fold K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000001064 204.0
TLS1_k127_56687_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000001489 125.0
TLS1_k127_56687_5 carboxymuconolactone decarboxylase - - - 0.000000000000000000000007145 106.0
TLS1_k127_56687_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000004361 101.0
TLS1_k127_5672969_0 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 290.0
TLS1_k127_5672969_1 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000000002286 179.0
TLS1_k127_5672969_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000753 143.0
TLS1_k127_5672969_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 0.0000000000000000000000000000003611 126.0
TLS1_k127_5682885_0 - - - - 0.0000000000005997 73.0
TLS1_k127_5682885_1 Histidine kinase - - - 0.00000004745 66.0
TLS1_k127_5682885_2 - - - - 0.0000002377 54.0
TLS1_k127_5690263_0 Acyl-CoA dehydrogenase N terminal - - - 1.207e-213 679.0
TLS1_k127_5690263_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000001688 198.0
TLS1_k127_5690263_2 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000001011 156.0
TLS1_k127_5690263_3 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000628 147.0
TLS1_k127_5690263_4 Bacterial regulatory proteins, tetR family - - - 0.0000003779 64.0
TLS1_k127_574078_0 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000178 179.0
TLS1_k127_574078_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000000000000000000000000001209 146.0
TLS1_k127_574078_2 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.000000000000000000476 93.0
TLS1_k127_574078_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000008885 59.0
TLS1_k127_5743700_0 Bacterial sugar transferase K21303 - 2.7.8.40 0.000000003335 57.0
TLS1_k127_5743700_1 Protein kinase domain K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000001742 63.0
TLS1_k127_5743700_2 polysaccharide biosynthetic process K01992 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704 - 0.0000001292 64.0
TLS1_k127_5754449_0 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000006397 252.0
TLS1_k127_5754449_1 AAA ATPase forming ring-shaped complexes K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000006762 158.0
TLS1_k127_5754449_2 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000000000000000000000000003125 135.0
TLS1_k127_5786509_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000005117 192.0
TLS1_k127_5786509_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000008914 82.0
TLS1_k127_5800351_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 380.0
TLS1_k127_5800351_1 Binding-protein-dependent transport system inner membrane component K15554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 304.0
TLS1_k127_5800351_2 ATPases associated with a variety of cellular activities K15578,K15579 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001846 264.0
TLS1_k127_5800351_3 - - - - 0.0000000000003288 76.0
TLS1_k127_5825868_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000001162 183.0
TLS1_k127_5825868_1 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K13940 GO:0008150,GO:0040007 1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8 0.00000000000000000000000000000001112 132.0
TLS1_k127_5825868_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000009111 135.0
TLS1_k127_5825868_3 - - - - 0.00000000000000000000000001197 120.0
TLS1_k127_5879450_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 411.0
TLS1_k127_5879450_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004484 257.0
TLS1_k127_5879450_2 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.000000000000000001864 96.0
TLS1_k127_5888324_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.422e-200 666.0
TLS1_k127_5888324_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 472.0
TLS1_k127_5888324_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 366.0
TLS1_k127_5888324_3 Acetyl propionyl-CoA carboxylase alpha subunit K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.00000000000000000000183 97.0
TLS1_k127_5899722_0 ComEC Rec2-related protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001835 286.0
TLS1_k127_5899722_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000008733 70.0
TLS1_k127_5910082_0 L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 432.0
TLS1_k127_5910082_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000004302 187.0
TLS1_k127_5910082_2 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000001242 113.0
TLS1_k127_5996432_0 acetylesterase activity - - - 0.00000000000000000000000000000000000000000000000000000002434 209.0
TLS1_k127_5996432_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000001256 204.0
TLS1_k127_5996432_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000001667 73.0
TLS1_k127_6072158_0 belongs to the aldehyde dehydrogenase family K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 1.483e-209 661.0
TLS1_k127_6072158_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000001855 157.0
TLS1_k127_6072158_2 Xylose isomerase-like TIM barrel K00457 - 1.13.11.27 0.0000000000000000000000000000000000000002011 156.0
TLS1_k127_6074326_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.059e-223 707.0
TLS1_k127_6074326_1 DEAD DEAH box helicase domain protein K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 3.659e-196 640.0
TLS1_k127_6074326_10 tyrosine recombinase K04763 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000601 161.0
TLS1_k127_6074326_11 NUDIX domain K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000000008425 119.0
TLS1_k127_6074326_12 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000002146 123.0
TLS1_k127_6074326_13 Acetyltransferase (GNAT) family - - - 0.0000001094 63.0
TLS1_k127_6074326_14 - - - - 0.0004985 49.0
TLS1_k127_6074326_2 Belongs to the AlaDH PNT family K00259 GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030312,GO:0036293,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 419.0
TLS1_k127_6074326_3 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 344.0
TLS1_k127_6074326_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001291 294.0
TLS1_k127_6074326_5 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000003373 260.0
TLS1_k127_6074326_6 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000003497 233.0
TLS1_k127_6074326_7 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000000000000000000006601 231.0
TLS1_k127_6074326_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000001199 188.0
TLS1_k127_6074326_9 PFAM Haloacid dehalogenase domain protein hydrolase K01101 - 3.1.3.41 0.00000000000000000000000000000000000000000376 169.0
TLS1_k127_6078131_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 531.0
TLS1_k127_6078131_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 365.0
TLS1_k127_6078131_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 324.0
TLS1_k127_6078131_3 Peptidase dimerisation domain K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000005905 263.0
TLS1_k127_6078131_4 Histidine kinase - - - 0.00000000000000000000000003749 123.0
TLS1_k127_6078131_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000008932 83.0
TLS1_k127_6085155_0 4Fe-4S dicluster domain - - - 6.119e-242 766.0
TLS1_k127_6085155_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000005491 192.0
TLS1_k127_6085155_10 - - - - 0.00005685 54.0
TLS1_k127_6085155_2 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000002813 185.0
TLS1_k127_6085155_3 amidohydrolase K01436,K06048 - - 0.000000000000000000000000000000001341 136.0
TLS1_k127_6085155_4 Transcriptional regulator - - - 0.0000000000000000000000000000007587 125.0
TLS1_k127_6085155_5 XdhC and CoxI family K07402 - - 0.000000000000000000000000000007594 121.0
TLS1_k127_6085155_6 translation release factor activity - - - 0.00000000000000000000000000004433 130.0
TLS1_k127_6085155_7 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.0000000000000000000000000004068 124.0
TLS1_k127_6085155_8 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000001725 119.0
TLS1_k127_6085155_9 Domain of unknown function (DUF4332) - - - 0.000000000000000000000000001769 118.0
TLS1_k127_6086278_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 3.726e-244 778.0
TLS1_k127_6086278_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000001851 191.0
TLS1_k127_6086278_2 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000007339 171.0
TLS1_k127_6086278_3 Adenosine/AMP deaminase - - - 0.0000000000000000000001121 102.0
TLS1_k127_6090983_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 5.471e-198 628.0
TLS1_k127_6093621_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 2.032e-206 654.0
TLS1_k127_6094665_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 533.0
TLS1_k127_6094665_1 Extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 490.0
TLS1_k127_6094665_2 Binding-protein-dependent transport system inner membrane component K02025,K10189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 418.0
TLS1_k127_6094665_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 389.0
TLS1_k127_6094665_4 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000001212 233.0
TLS1_k127_6101236_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003609 271.0
TLS1_k127_6101236_1 enoyl-CoA hydratase isomerase family K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000002259 197.0
TLS1_k127_6101236_2 oxidoreductase K00010,K16043 - 1.1.1.18,1.1.1.369,1.1.1.370 0.00000000000004348 78.0
TLS1_k127_6105435_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002028 287.0
TLS1_k127_6105435_1 metal-dependent phosphohydrolase 7TM intracellular region K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000001444 256.0
TLS1_k127_6105435_2 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000001632 213.0
TLS1_k127_6105435_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000002006 180.0
TLS1_k127_6105435_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000001889 153.0
TLS1_k127_6105435_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000009287 113.0
TLS1_k127_6105435_6 dehydratase K01724 - 4.2.1.96 0.0000000000000000000000008777 106.0
TLS1_k127_6111933_0 Aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 399.0
TLS1_k127_6111933_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 314.0
TLS1_k127_6111933_2 PA domain - - - 0.000000000000001224 77.0
TLS1_k127_6117372_0 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 291.0
TLS1_k127_6117372_1 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000003592 203.0
TLS1_k127_6117372_2 polyketide cyclase - - - 0.000000000000000000000000000000000000000154 154.0
TLS1_k127_6117372_3 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.000194 46.0
TLS1_k127_6122637_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 355.0
TLS1_k127_6122637_1 Phosphotransferase enzyme family K00897 - 2.7.1.95 0.00000000000000000000000000000000000000000000000000000000000000569 224.0
TLS1_k127_6122637_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000006674 162.0
TLS1_k127_6122637_4 PFAM DinB family protein - - - 0.0000000000000000000000003095 111.0
TLS1_k127_6122637_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000005037 67.0
TLS1_k127_6123417_0 Putative glutamine amidotransferase K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 457.0
TLS1_k127_6123417_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000003042 229.0
TLS1_k127_6123417_2 Aerotolerance regulator N-terminal - - - 0.00000000000002048 81.0
TLS1_k127_6131511_0 (Pantothenic acid kinase)) K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000008045 255.0
TLS1_k127_6131511_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000001803 229.0
TLS1_k127_6131511_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000005772 154.0
TLS1_k127_6132693_0 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 554.0
TLS1_k127_6143305_0 Phosphate starvation protein PhoH K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 356.0
TLS1_k127_6143305_1 PFAM helix-turn-helix domain protein - - - 0.000000000000000001413 90.0
TLS1_k127_6143305_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000001028 68.0
TLS1_k127_6143432_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005156 282.0
TLS1_k127_6143432_1 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000011 250.0
TLS1_k127_6143432_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000001763 179.0
TLS1_k127_6143432_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000001099 149.0
TLS1_k127_6143432_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000002283 111.0
TLS1_k127_6143432_5 Transglycosylase associated protein - - - 0.000000000000000000001004 98.0
TLS1_k127_6143432_6 transglycosylase associated protein - - - 0.0000000000000000001547 91.0
TLS1_k127_6153707_0 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 345.0
TLS1_k127_6153707_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000003211 141.0
TLS1_k127_6165115_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 353.0
TLS1_k127_6165115_1 CoA-transferase family III K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 332.0
TLS1_k127_6165115_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 322.0
TLS1_k127_6165115_3 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000005929 221.0
TLS1_k127_6165115_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000001143 202.0
TLS1_k127_6165115_5 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.000000000000000001041 96.0
TLS1_k127_6165115_6 F420-dependent oxidoreductase - - - 0.00000000000000002564 83.0
TLS1_k127_6176216_0 Luciferase-like monooxygenase - - - 0.000000000182 67.0
TLS1_k127_6176216_1 - - - - 0.00000008327 61.0
TLS1_k127_6183168_0 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001944 296.0
TLS1_k127_6184600_0 PFAM sodium hydrogen exchanger - - - 3.256e-210 674.0
TLS1_k127_6184600_1 oxidoreductase K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 258.0
TLS1_k127_6184600_2 COGs COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0000000000000000000000000000000000000000000000000008104 188.0
TLS1_k127_6184600_3 3-hydroxyacyl-CoA dehydrogenase K00074 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0008150,GO:0008152,GO:0008610,GO:0008691,GO:0009056,GO:0009058,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0030497,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0072330,GO:0075136,GO:1901575,GO:1901576 1.1.1.157 0.00000000000000000000000000000000000000001379 154.0
TLS1_k127_6190751_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 486.0
TLS1_k127_6190751_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 348.0
TLS1_k127_6190751_10 - - - - 0.00000000000000000000002616 107.0
TLS1_k127_6190751_11 Family of unknown function (DUF5317) - - - 0.000000000000000000005314 100.0
TLS1_k127_6190751_12 heme binding K21472 - - 0.00000000000000000001296 105.0
TLS1_k127_6190751_13 - - - - 0.0000000000002309 71.0
TLS1_k127_6190751_14 poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 - - 0.00008955 49.0
TLS1_k127_6190751_2 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 321.0
TLS1_k127_6190751_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 328.0
TLS1_k127_6190751_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 315.0
TLS1_k127_6190751_5 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000001565 199.0
TLS1_k127_6190751_6 HD domain - - - 0.0000000000000000000000000000000000000000004279 177.0
TLS1_k127_6190751_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000001583 168.0
TLS1_k127_6190751_8 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.00000000000000000000000000000000000000001798 171.0
TLS1_k127_6190751_9 family 25 K01185,K07273 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.17 0.000000000000000000000000002782 125.0
TLS1_k127_6195498_0 PFAM ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 417.0
TLS1_k127_6195498_1 Aminotransferase class v - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 315.0
TLS1_k127_6195498_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001214 289.0
TLS1_k127_6195498_3 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000118 258.0
TLS1_k127_6195498_4 Abortive infection protein K07052 - - 0.0000000000000000000000000000005303 131.0
TLS1_k127_6195498_5 COG3030 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.00000000000000000000005338 105.0
TLS1_k127_6196319_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003758 225.0
TLS1_k127_6196319_1 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000003132 161.0
TLS1_k127_6196319_2 Universal stress protein - - - 0.00000000000000001606 87.0
TLS1_k127_6196319_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000151 70.0
TLS1_k127_6196319_4 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000002172 62.0
TLS1_k127_6204375_0 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 474.0
TLS1_k127_6204375_1 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.000000000000000000000000000001554 128.0
TLS1_k127_6204375_2 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000000000006391 119.0
TLS1_k127_6204375_3 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000001838 93.0
TLS1_k127_6204375_4 COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.000004886 48.0
TLS1_k127_6210158_0 Sodium hydrogen exchanger - - - 0.00000000002421 65.0
TLS1_k127_6217443_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 376.0
TLS1_k127_6217443_1 COG0451 Nucleoside-diphosphate-sugar epimerases K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000002324 177.0
TLS1_k127_6227921_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004285 276.0
TLS1_k127_6227921_1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000001958 221.0
TLS1_k127_6227921_2 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000004674 216.0
TLS1_k127_6227921_3 phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000006178 163.0
TLS1_k127_6227921_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000003466 144.0
TLS1_k127_6236788_0 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 386.0
TLS1_k127_6236788_1 His Kinase A (phosphoacceptor) domain K07654 - 2.7.13.3 0.000000000000000000000000001971 128.0
TLS1_k127_6237980_0 Major facilitator Superfamily - - - 0.000000000000007679 76.0
TLS1_k127_623860_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 306.0
TLS1_k127_623860_1 Clp amino terminal domain, pathogenicity island component - - - 0.00000000000000000000131 102.0
TLS1_k127_623860_2 - - - - 0.000000000000000005171 89.0
TLS1_k127_623860_3 Aminoglycoside phosphotransferase - - - 0.00003723 46.0
TLS1_k127_6245409_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 438.0
TLS1_k127_6245409_1 Belongs to the SAICAR synthetase family K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 334.0
TLS1_k127_6245409_2 BON domain - - - 0.0000000000000000000000000000000000000007582 158.0
TLS1_k127_6245409_3 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000001198 129.0
TLS1_k127_6245409_4 Thioesterase superfamily K02614 - - 0.00000000000000000007686 94.0
TLS1_k127_6255338_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 400.0
TLS1_k127_6255338_1 Branched-chain amino acid transport system permease K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 369.0
TLS1_k127_6255338_2 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 316.0
TLS1_k127_6255338_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 309.0
TLS1_k127_6255338_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.000000000000000000000000000000000000000000000000000000000001557 222.0
TLS1_k127_6255338_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000002191 220.0
TLS1_k127_6255338_6 branched-chain amino acid K01996 - - 0.0000000000000000000000000002684 116.0
TLS1_k127_6255338_7 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0002245 53.0
TLS1_k127_6264696_0 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 551.0
TLS1_k127_6264696_1 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002757 272.0
TLS1_k127_6264696_2 Xaa-Pro aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002655 244.0
TLS1_k127_6273201_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1168.0
TLS1_k127_6273201_1 subunit of a heme lyase K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001193 268.0
TLS1_k127_6273201_2 SatD family (SatD) - - - 0.00000000000000000000000000000005039 133.0
TLS1_k127_6273201_3 beta-1,4-mannooligosaccharide phosphorylase - - - 0.0000000000000000000000003136 106.0
TLS1_k127_6273201_4 Psort location CytoplasmicMembrane, score - - - 0.00000000000001424 80.0
TLS1_k127_6275989_0 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000002503 222.0
TLS1_k127_6275989_1 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000006179 199.0
TLS1_k127_6279950_0 pilus assembly protein ATPase CpaF K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 382.0
TLS1_k127_6279950_1 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000000000000001183 226.0
TLS1_k127_6292512_0 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 394.0
TLS1_k127_6292512_1 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000004877 66.0
TLS1_k127_6292512_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00008879 48.0
TLS1_k127_6299317_0 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008306 286.0
TLS1_k127_6299317_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001041 278.0
TLS1_k127_6299317_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000002015 205.0
TLS1_k127_6299317_3 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.000000001543 68.0
TLS1_k127_6308268_0 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000176 240.0
TLS1_k127_6308268_1 -acetyltransferase - - - 0.00000000000000000000000000000000000000000000005427 172.0
TLS1_k127_6308268_2 acetylesterase activity - - - 0.000000000000000000000000000000000000000000007279 176.0
TLS1_k127_6308268_3 Nitroreductase family - - - 0.00000000000000001358 83.0
TLS1_k127_6308268_4 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.00006763 47.0
TLS1_k127_6309072_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.888e-263 827.0
TLS1_k127_6309072_1 protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000003149 159.0
TLS1_k127_6309072_2 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000000009724 121.0
TLS1_k127_6309072_3 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000000000004873 107.0
TLS1_k127_6309072_4 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000005553 73.0
TLS1_k127_6309072_5 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000001472 59.0
TLS1_k127_6309072_6 sigma factor antagonist activity - - - 0.0001698 50.0
TLS1_k127_6319919_0 drug exporters of the RND superfamily K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 547.0
TLS1_k127_6319919_1 Bacterial low temperature requirement A protein (LtrA) - - - 0.0000000000000000000000000000007607 132.0
TLS1_k127_6348347_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 588.0
TLS1_k127_6348347_1 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000001022 141.0
TLS1_k127_6363512_0 ABC-type Fe3 transport system permease component K02011,K02063 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 433.0
TLS1_k127_6363512_1 ABC transporter, periplasmic binding protein, thiB subfamily K02064 - - 0.00000000000000000000000000000000000000000000000000000000001203 211.0
TLS1_k127_6370731_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 329.0
TLS1_k127_6370731_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000008875 215.0
TLS1_k127_6370731_2 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000224 188.0
TLS1_k127_637331_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 298.0
TLS1_k127_637331_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00140,K00823 - 1.2.1.18,1.2.1.27,2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000002972 253.0
TLS1_k127_637331_2 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004156 256.0
TLS1_k127_637331_3 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000001715 222.0
TLS1_k127_637331_4 PFAM Rieske 2Fe-2S domain K05710 - - 0.00000000000000000000001979 105.0
TLS1_k127_637331_5 FeS assembly ATPase SufC K09013 - - 0.00000000000000000001169 94.0
TLS1_k127_6375326_0 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 361.0
TLS1_k127_6375326_1 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000001674 136.0
TLS1_k127_6397556_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 403.0
TLS1_k127_6397556_1 ATPase MipZ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 335.0
TLS1_k127_6397556_10 N-acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.00005102 52.0
TLS1_k127_6397556_2 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004268 259.0
TLS1_k127_6397556_3 DNA polymerase III beta subunit K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000055 218.0
TLS1_k127_6397556_4 Putative single-stranded nucleic acids-binding domain K06346 - - 0.00000000000000000000000000000002261 139.0
TLS1_k127_6397556_5 60Kd inner membrane protein K03217 - - 0.00000000000000000000000000001817 128.0
TLS1_k127_6397556_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000005233 115.0
TLS1_k127_6397556_7 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000004118 91.0
TLS1_k127_6397556_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000002387 62.0
TLS1_k127_6397556_9 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.000000006133 63.0
TLS1_k127_6406489_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 2.73e-225 712.0
TLS1_k127_6406489_1 Alcohol dehydrogenase GroES-like domain K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 314.0
TLS1_k127_6406489_2 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000001621 207.0
TLS1_k127_6406489_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000001005 202.0
TLS1_k127_6406489_4 Small subunit of acetolactate synthase K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000005164 168.0
TLS1_k127_6415632_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 463.0
TLS1_k127_6415632_1 aminotransferase class I and II K14261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007727 457.0
TLS1_k127_6415632_10 Binding-protein-dependent transport system inner membrane component K05846 - - 0.000000000000000000000000000007299 121.0
TLS1_k127_6415632_11 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000001632 105.0
TLS1_k127_6415632_12 Protein of unknown function (DUF1232) - - - 0.000000000000000000002399 99.0
TLS1_k127_6415632_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000001791 84.0
TLS1_k127_6415632_14 - - - - 0.0000001449 55.0
TLS1_k127_6415632_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 387.0
TLS1_k127_6415632_3 PFAM Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 357.0
TLS1_k127_6415632_4 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 317.0
TLS1_k127_6415632_5 TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004068 282.0
TLS1_k127_6415632_6 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000001872 246.0
TLS1_k127_6415632_7 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000001131 233.0
TLS1_k127_6415632_8 ABC transporter (Permease) K05846 - - 0.000000000000000000000000000000000000000000000000000003306 203.0
TLS1_k127_6415632_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000002175 172.0
TLS1_k127_6418480_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 508.0
TLS1_k127_6418480_1 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 315.0
TLS1_k127_6418480_2 Putative methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002524 247.0
TLS1_k127_6418480_3 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0000000006216 70.0
TLS1_k127_6418480_4 Predicted membrane protein (DUF2207) - - - 0.0000009344 54.0
TLS1_k127_6427945_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 561.0
TLS1_k127_6427945_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000008946 113.0
TLS1_k127_6427945_2 Cysteine-rich domain K11473 - - 0.000000000000000001925 88.0
TLS1_k127_6434870_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 565.0
TLS1_k127_6434870_1 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 461.0
TLS1_k127_6434870_2 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 345.0
TLS1_k127_6434870_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 318.0
TLS1_k127_6434870_4 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001504 254.0
TLS1_k127_6434870_5 serine threonine protein kinase - - - 0.0000000000000001693 92.0
TLS1_k127_6434870_6 FR47-like protein K03789,K14742 - 2.3.1.128 0.000001531 59.0
TLS1_k127_6443742_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 525.0
TLS1_k127_6443742_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000003389 151.0
TLS1_k127_6445770_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 451.0
TLS1_k127_6445770_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.00000000000000000001019 100.0
TLS1_k127_6449760_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 535.0
TLS1_k127_6449760_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000001579 172.0
TLS1_k127_6449760_2 DNA primase, small subunit - - - 0.00000000000000000000000000000005686 130.0
TLS1_k127_6464115_0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002195 210.0
TLS1_k127_6464115_1 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000004224 173.0
TLS1_k127_6464115_2 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000004996 165.0
TLS1_k127_6464115_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000001253 151.0
TLS1_k127_6487219_0 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 - 6.3.1.19 1.029e-217 682.0
TLS1_k127_6487219_1 Proteasomal ATPase OB/ID domain K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 4.552e-215 678.0
TLS1_k127_6487219_2 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 519.0
TLS1_k127_6487219_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006254 269.0
TLS1_k127_6487219_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000007462 252.0
TLS1_k127_6487219_5 WYL domain K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000008702 114.0
TLS1_k127_6487219_6 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 - - 0.00000003861 56.0
TLS1_k127_6503456_0 3-deoxy-7-phosphoheptulonate synthase activity K00661,K03856,K04092,K04093,K04516,K04518,K14170,K14187 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,2.3.1.79,2.5.1.54,4.2.1.51,5.4.99.5 9.153e-199 634.0
TLS1_k127_6503456_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000001459 74.0
TLS1_k127_6508121_0 Electron transfer DM13 - - - 0.00000000000000000004038 96.0
TLS1_k127_6508121_1 Acetyltransferase (GNAT) family - - - 0.000000001085 68.0
TLS1_k127_6508121_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0002301 52.0
TLS1_k127_653_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 340.0
TLS1_k127_653_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002657 248.0
TLS1_k127_6551218_0 DEAD DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001572 266.0
TLS1_k127_6551218_1 transcriptional regulator K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000003221 182.0
TLS1_k127_6551218_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000599 150.0
TLS1_k127_6551218_3 - - - - 0.0000000003016 65.0
TLS1_k127_6551218_4 mttA/Hcf106 family K03117 - - 0.00004291 53.0
TLS1_k127_6551218_5 WYL domain - - - 0.0001568 48.0
TLS1_k127_6559776_0 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000009891 166.0
TLS1_k127_6563391_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000001409 192.0
TLS1_k127_6563391_1 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.000000000000008353 87.0
TLS1_k127_6563391_2 DivIVA domain protein K04074 - - 0.000000000005034 73.0
TLS1_k127_6563391_3 membrane K02221 - - 0.00000000002967 66.0
TLS1_k127_6563391_4 Multi-copper polyphenol oxidoreductase laccase K05810 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - 0.0000000489 56.0
TLS1_k127_6578789_0 DNA polymerase beta thumb K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 614.0
TLS1_k127_6578789_1 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000008562 90.0
TLS1_k127_6579447_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000007702 199.0
TLS1_k127_6579447_1 Histone deacetylase domain - - - 0.0000000000000000000007112 97.0
TLS1_k127_6618601_0 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001683 271.0
TLS1_k127_6618601_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000005084 161.0
TLS1_k127_6618601_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.0000000000000000000000000000000000000003898 154.0
TLS1_k127_6618601_3 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000008547 75.0
TLS1_k127_6639065_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002825 279.0
TLS1_k127_6639065_1 Pfam Amidohydrolase K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000004933 224.0
TLS1_k127_664149_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 560.0
TLS1_k127_664149_1 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 508.0
TLS1_k127_664149_2 Belongs to the allantoicase family K01477 - 3.5.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 418.0
TLS1_k127_664149_3 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin K00365 - 1.7.3.3 0.0000000000000000000000000000000000000000000000000000000000000003356 233.0
TLS1_k127_664149_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000008046 215.0
TLS1_k127_664149_5 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000002167 193.0
TLS1_k127_664149_6 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0033971,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.2.17 0.000000000000000000000006756 109.0
TLS1_k127_6651651_0 Pyridoxal-phosphate dependent enzyme K17989 - 4.3.1.17,4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002159 286.0
TLS1_k127_6651651_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000006292 181.0
TLS1_k127_6651651_2 translation initiation factor activity K06996 - - 0.0000000000000000000001149 102.0
TLS1_k127_6651651_3 PFAM Patatin - - - 0.000006097 56.0
TLS1_k127_6655922_0 PFAM BMC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 291.0
TLS1_k127_6655922_1 COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.000000000000000000000000000000000009552 138.0
TLS1_k127_6655922_2 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000000000002713 117.0
TLS1_k127_6655922_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000004504 96.0
TLS1_k127_6664715_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004457 253.0
TLS1_k127_6664715_1 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000001273 216.0
TLS1_k127_6664715_2 mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000007678 185.0
TLS1_k127_6664715_3 ABC transporter - - - 0.000000000000000000000000000000000278 150.0
TLS1_k127_6664715_4 ABC transporter - - - 0.0000000000000000000000000000000197 141.0
TLS1_k127_6664715_5 PFAM Diacylglycerol kinase, catalytic - - - 0.00000000000000000000000008148 118.0
TLS1_k127_6670076_0 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000002699 159.0
TLS1_k127_6670076_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000003547 102.0
TLS1_k127_6670076_2 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000006609 86.0
TLS1_k127_6670076_3 glutamate-1-semialdehyde 2,1-aminomutase activity K01845 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 0.0008668 42.0
TLS1_k127_6700557_0 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 362.0
TLS1_k127_6700557_1 phosphinothricin N-acetyltransferase activity K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000008604 203.0
TLS1_k127_6700557_2 endonuclease - - - 0.000000000000000000000000000000000000000000000000001105 190.0
TLS1_k127_6700557_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000005849 160.0
TLS1_k127_6700557_4 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0001109 47.0
TLS1_k127_6717370_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1119.0
TLS1_k127_6717370_1 O-methyltransferase - - - 0.00000000000000000000000000000000000003039 151.0
TLS1_k127_6717370_2 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.0000000000000000000000000000004656 128.0
TLS1_k127_6717370_3 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.000000000000000000000000000002069 128.0
TLS1_k127_6717370_4 translation release factor activity - - - 0.0000000000000000000000000008409 126.0
TLS1_k127_671954_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1349.0
TLS1_k127_671954_1 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000005588 147.0
TLS1_k127_671954_2 Bacterial extracellular solute-binding protein K11069 - - 0.0000000000000000000000000006662 128.0
TLS1_k127_6721567_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 575.0
TLS1_k127_6721567_1 helicase superfamily c-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 430.0
TLS1_k127_6721567_2 alpha amylase, catalytic K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000001079 216.0
TLS1_k127_6721567_3 S-layer domain protein - - - 0.000003922 57.0
TLS1_k127_6743613_0 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004587 289.0
TLS1_k127_6743613_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004624 274.0
TLS1_k127_6743613_2 Transcriptional regulator - - - 0.000000000000000000000000000004653 122.0
TLS1_k127_6743613_3 PFAM Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000001501 79.0
TLS1_k127_6759_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 505.0
TLS1_k127_6759_1 Zinc-binding dehydrogenase K00004 - 1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000000000003804 228.0
TLS1_k127_6759_2 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000003605 214.0
TLS1_k127_6759_3 F420H(2)-dependent quinone reductase - - - 0.00000003294 55.0
TLS1_k127_6770641_0 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 314.0
TLS1_k127_6770641_1 Rieske 2Fe-2S K00479 - - 0.0000000000000000000000000000000000000000000000001771 180.0
TLS1_k127_6770641_2 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000347 178.0
TLS1_k127_6853191_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 452.0
TLS1_k127_6853191_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000009722 259.0
TLS1_k127_6853191_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000867 187.0
TLS1_k127_6853191_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.00000000000000000000000000000000000000001916 160.0
TLS1_k127_6853191_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000003528 139.0
TLS1_k127_6883091_0 all-trans-retinol 13,14-reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 488.0
TLS1_k127_6919708_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1125.0
TLS1_k127_6919708_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 365.0
TLS1_k127_6919708_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000002857 249.0
TLS1_k127_6919708_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000009776 194.0
TLS1_k127_6919708_4 response to oxidative stress - - - 0.00000000000000000000000000000001414 132.0
TLS1_k127_6922076_0 Thimet oligopeptidase 1 K01392,K01393 GO:0000209,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005829,GO:0006464,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0016567,GO:0016787,GO:0019538,GO:0023052,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032446,GO:0033218,GO:0034641,GO:0035556,GO:0036211,GO:0042277,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0070013,GO:0070647,GO:0071704,GO:0140096,GO:1901564 3.4.24.15,3.4.24.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 376.0
TLS1_k127_6922076_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K12954,K12956,K17686,K21887 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0042221,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0050896,GO:0051704,GO:0071944 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 376.0
TLS1_k127_6922076_3 mercury ion transmembrane transporter activity K07213 - - 0.0005911 49.0
TLS1_k127_6963406_0 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 321.0
TLS1_k127_6963406_1 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000001042 119.0
TLS1_k127_6963406_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000001965 81.0
TLS1_k127_6963406_3 Cysteine-rich secretory protein family - - - 0.0000001934 63.0
TLS1_k127_6963406_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0001024 46.0
TLS1_k127_7022823_0 zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000006603 238.0
TLS1_k127_7022823_1 His Kinase A (phosphoacceptor) domain - - - 0.000000005266 68.0
TLS1_k127_7029944_0 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 477.0
TLS1_k127_7029944_1 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008093 252.0
TLS1_k127_7029944_2 PFAM Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000001664 223.0
TLS1_k127_7029944_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0008741 42.0
TLS1_k127_7082314_0 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 443.0
TLS1_k127_7082314_1 tRNA N-acetyltransferase activity K00657,K06957 GO:0000049,GO:0000154,GO:0002097,GO:0002101,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0022613,GO:0030490,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0051391,GO:0051392,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1904812,GO:1990882,GO:1990883,GO:1990884 2.3.1.193,2.3.1.57 0.0000000000000000000000000000000000000000000000000000000000000000006349 234.0
TLS1_k127_7097383_0 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000007225 143.0
TLS1_k127_7097383_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000005334 121.0
TLS1_k127_7097383_2 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000004204 109.0
TLS1_k127_7097383_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0003727 51.0
TLS1_k127_7101263_0 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 473.0
TLS1_k127_7101263_1 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 320.0
TLS1_k127_7101263_2 BetI-type transcriptional repressor, C-terminal - - - 0.0000000000000000000000000008043 121.0
TLS1_k127_7110894_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 3.526e-219 695.0
TLS1_k127_7110894_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 527.0
TLS1_k127_7110894_10 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000002313 138.0
TLS1_k127_7110894_11 DNA protecting protein DprA K04096 - - 0.00000000001858 68.0
TLS1_k127_7110894_12 acetyltransferase K20791 - 2.3.1.255 0.0000000003381 68.0
TLS1_k127_7110894_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 330.0
TLS1_k127_7110894_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 307.0
TLS1_k127_7110894_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 295.0
TLS1_k127_7110894_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 287.0
TLS1_k127_7110894_6 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000001857 224.0
TLS1_k127_7110894_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000293 211.0
TLS1_k127_7110894_8 PFAM peptidase M50 K11749 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000008093 209.0
TLS1_k127_7110894_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000003569 190.0
TLS1_k127_7121040_0 Aminotransferase class-V - - - 2.085e-222 706.0
TLS1_k127_7121040_1 DNA primase, small subunit K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 349.0
TLS1_k127_7121040_10 - - - - 0.000000000000000000000005772 108.0
TLS1_k127_7121040_11 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.00000000000004705 73.0
TLS1_k127_7121040_12 ABC-2 family transporter protein K01992 - - 0.0000000001496 73.0
TLS1_k127_7121040_13 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0005687 53.0
TLS1_k127_7121040_2 ATP dependent DNA ligase domain - GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 333.0
TLS1_k127_7121040_3 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 308.0
TLS1_k127_7121040_4 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000185 288.0
TLS1_k127_7121040_6 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000212 222.0
TLS1_k127_7121040_7 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.000000000000000000000000000103 130.0
TLS1_k127_7121040_8 amidohydrolase - - - 0.0000000000000000000000000002513 134.0
TLS1_k127_7121040_9 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000004452 115.0
TLS1_k127_7124344_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002692 258.0
TLS1_k127_7124344_1 Peptidase family M23 K21472 - - 0.00000000000001487 87.0
TLS1_k127_7124344_2 Aminotransferase K00826 - 2.6.1.42 0.000000000317 64.0
TLS1_k127_7142264_0 NADPH quinone K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 324.0
TLS1_k127_7142264_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000204 297.0
TLS1_k127_7142264_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001526 259.0
TLS1_k127_7142264_3 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000007065 169.0
TLS1_k127_7142264_4 Universal stress protein family - - - 0.000000000000000000000001161 114.0
TLS1_k127_7142264_5 Cyclic nucleotide-monophosphate binding domain K00384 - 1.8.1.9 0.0000000001056 62.0
TLS1_k127_7142947_0 COG0433 Predicted ATPase K06915 - - 7.736e-199 631.0
TLS1_k127_7142947_1 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 306.0
TLS1_k127_7142947_2 P-loop containing region of AAA domain K03546 - - 0.00000000000000000000000000000000000000000000000001068 200.0
TLS1_k127_7147873_0 Belongs to the EPSP synthase family. MurA subfamily K00790 GO:0008150,GO:0040007 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 436.0
TLS1_k127_7147873_1 Lao ao transport system K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000001462 235.0
TLS1_k127_7147873_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000002429 215.0
TLS1_k127_7147873_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000002993 179.0
TLS1_k127_7147873_4 SpoIID LytB domain protein K06381 - - 0.00000000000000000000000000000000007661 150.0
TLS1_k127_7147873_5 Nitrogen fixation protein NifU - - - 0.000000000000007149 81.0
TLS1_k127_7147873_6 Redoxin - - - 0.000000005398 60.0
TLS1_k127_7161221_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 415.0
TLS1_k127_7161221_1 N-4 methylation of cytosine K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 394.0
TLS1_k127_7161221_2 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000001782 141.0
TLS1_k127_7161221_3 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000005881 143.0
TLS1_k127_7161221_4 - - - - 0.00000000000000000000000000000001541 138.0
TLS1_k127_7161221_5 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000001629 97.0
TLS1_k127_7161221_6 ATP-grasp domain - - - 0.00000000000000000004643 99.0
TLS1_k127_7161221_7 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000000000000004877 102.0
TLS1_k127_7167828_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 308.0
TLS1_k127_7167828_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001319 131.0
TLS1_k127_7167828_2 copper resistance K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000906 49.0
TLS1_k127_7182902_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 436.0
TLS1_k127_7182902_1 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000003379 174.0
TLS1_k127_7182902_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000005562 171.0
TLS1_k127_7182902_3 Thioesterase superfamily - - - 0.0000000000000000000000000000004651 136.0
TLS1_k127_7182902_5 - - - - 0.000000000000000000000003184 114.0
TLS1_k127_7182902_6 Amidohydrolase family - - - 0.0000000000000000000327 103.0
TLS1_k127_7188198_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 1.105e-244 783.0
TLS1_k127_7188198_1 enoyl-CoA hydratase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.0000000000000007831 81.0
TLS1_k127_7212267_0 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000001982 214.0
TLS1_k127_7212267_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000006245 175.0
TLS1_k127_7212267_2 SnoaL-like polyketide cyclase K15945 - - 0.00000000000000000000000000000000000008057 147.0
TLS1_k127_7230679_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K17216 - 2.5.1.134,2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 437.0
TLS1_k127_7230679_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 338.0
TLS1_k127_7230679_2 Belongs to the ATCase OTCase family K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 334.0
TLS1_k127_7230679_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004845,GO:0004849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016763,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000001074 215.0
TLS1_k127_7230679_4 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000002059 130.0
TLS1_k127_7230679_5 enzyme binding K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.0000000000000002285 89.0
TLS1_k127_7233561_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 433.0
TLS1_k127_7233561_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000002682 234.0
TLS1_k127_7233561_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000005053 224.0
TLS1_k127_7233561_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000001039 213.0
TLS1_k127_7233561_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000004495 164.0
TLS1_k127_7233561_5 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000001085 158.0
TLS1_k127_7233561_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000002465 146.0
TLS1_k127_7233561_7 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000006623 65.0
TLS1_k127_7233561_8 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000003915 67.0
TLS1_k127_7233561_9 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0004487 49.0
TLS1_k127_7242512_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 390.0
TLS1_k127_7242512_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0008150,GO:0040007 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 342.0
TLS1_k127_7242512_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000913 253.0
TLS1_k127_7242512_3 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000001237 217.0
TLS1_k127_7242512_4 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00002196 47.0
TLS1_k127_7245419_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.192e-196 625.0
TLS1_k127_7256850_0 Creatinase/Prolidase N-terminal domain K01271,K15783 - 3.4.13.9,3.5.4.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 504.0
TLS1_k127_7256850_1 3-keto-5-aminohexanoate cleavage protein K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 311.0
TLS1_k127_7256850_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K16843 - 1.1.1.310 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 312.0
TLS1_k127_7256850_3 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 288.0
TLS1_k127_7256850_4 PFAM Bacterial regulatory proteins, gntR family - - - 0.0000000000000000000000000000000000002547 149.0
TLS1_k127_7262910_0 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 510.0
TLS1_k127_7262910_1 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 377.0
TLS1_k127_7262910_2 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007473 276.0
TLS1_k127_7262910_3 Phenylacetate-CoA oxygenase K02610 - - 0.00000000000000000000000000000001627 130.0
TLS1_k127_7275394_0 Belongs to the helicase family. UvrD subfamily K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 379.0
TLS1_k127_7275394_1 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000000004324 192.0
TLS1_k127_7275394_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000005777 59.0
TLS1_k127_7279839_0 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 356.0
TLS1_k127_7279839_1 Alanine dehydrogenase/PNT, C-terminal domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000454 280.0
TLS1_k127_7290736_0 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001559 281.0
TLS1_k127_7290736_1 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005922 276.0
TLS1_k127_7290736_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000002512 207.0
TLS1_k127_7296604_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.178e-217 697.0
TLS1_k127_7296604_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 425.0
TLS1_k127_7296604_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 394.0
TLS1_k127_7296604_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 316.0
TLS1_k127_7296604_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000006986 203.0
TLS1_k127_7296604_5 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000001284 74.0
TLS1_k127_7310829_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001953 285.0
TLS1_k127_7310829_1 ABC-type Na efflux pump, permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000008437 234.0
TLS1_k127_7314766_0 Stage II sporulation E family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 498.0
TLS1_k127_7314766_1 Transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 439.0
TLS1_k127_7314766_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000008485 183.0
TLS1_k127_7314766_3 - - - - 0.00000000000000000000000000000000000000000005506 171.0
TLS1_k127_7314766_4 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000009967 128.0
TLS1_k127_7314766_5 antisigma factor binding K03090,K04749,K06378 - - 0.000000000000000000000000001002 115.0
TLS1_k127_7319071_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000008333 200.0
TLS1_k127_7319071_1 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000003482 128.0
TLS1_k127_7319071_2 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.0000000000000000000000006594 110.0
TLS1_k127_7329299_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 1.314e-216 683.0
TLS1_k127_7329299_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 426.0
TLS1_k127_7329299_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 307.0
TLS1_k127_7329299_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000004054 173.0
TLS1_k127_7332647_0 Mur ligase family, glutamate ligase domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 394.0
TLS1_k127_7332647_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 378.0
TLS1_k127_7332647_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 335.0
TLS1_k127_7332647_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 295.0
TLS1_k127_7332647_4 carboxylic ester hydrolase activity K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000006938 203.0
TLS1_k127_7332647_5 Histidine kinase - - - 0.00000000000000000000000000000000000002663 166.0
TLS1_k127_7332647_6 - - - - 0.000000003869 62.0
TLS1_k127_7335583_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 308.0
TLS1_k127_7335583_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000002273 194.0
TLS1_k127_7335583_2 Iron-sulphur cluster biosynthesis K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.000000000000000000000000000000000000006112 149.0
TLS1_k127_7335583_3 heme binding K21471,K21472 - - 0.0000000000000000000000000000000003113 151.0
TLS1_k127_7335583_4 RDD family - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000009832 110.0
TLS1_k127_7349029_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 595.0
TLS1_k127_7349029_1 Putative serine esterase (DUF676) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002603 269.0
TLS1_k127_7349029_2 SPTR Q471D1 TPR repeat Bacterial transcriptional activator domain Tetratricopeptide TPR_4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001491 268.0
TLS1_k127_7349029_3 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000006119 148.0
TLS1_k127_7349029_4 sequence-specific DNA binding - - - 0.000000004657 70.0
TLS1_k127_7355679_0 4-hydroxy-2-oxoglutarate aldolase K18123 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006081,GO:0006082,GO:0006090,GO:0006520,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008700,GO:0009056,GO:0009058,GO:0009063,GO:0009436,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0016833,GO:0019470,GO:0019471,GO:0019752,GO:0031974,GO:0032787,GO:0033609,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046185,GO:0046394,GO:0046395,GO:0046487,GO:0046983,GO:0070013,GO:0071704,GO:0072329,GO:0072330,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.3.16 0.0000000000000000000000000000000000005443 150.0
TLS1_k127_7355679_1 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000004259 131.0
TLS1_k127_7355679_2 SCP-2 sterol transfer family - - - 0.000000000000000000003949 97.0
TLS1_k127_7355679_3 TadE-like protein - - - 0.0000000005803 68.0
TLS1_k127_7355679_4 TadE-like protein - - - 0.000000244 60.0
TLS1_k127_7355679_5 von Willebrand factor, type A K07114 - - 0.0004664 51.0
TLS1_k127_7355679_6 TadE-like protein - - - 0.0005955 49.0
TLS1_k127_7359006_0 PspC domain - - - 0.00000000000000000000000000000000001541 149.0
TLS1_k127_7359006_1 - - - - 0.000000000000000000000003397 105.0
TLS1_k127_7361934_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 305.0
TLS1_k127_7361934_1 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18958 GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700 - 0.0000000000000007524 83.0
TLS1_k127_7361934_2 retrograde transport, endosome to Golgi K07095 - - 0.000001957 55.0
TLS1_k127_7364053_0 UvrD-like helicase C-terminal domain K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 2.935e-238 758.0
TLS1_k127_7364053_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.131e-213 675.0
TLS1_k127_7364053_2 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000006336 282.0
TLS1_k127_7364053_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000006089 154.0
TLS1_k127_7364053_4 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000007062 65.0
TLS1_k127_7370712_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 458.0
TLS1_k127_7370712_1 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 385.0
TLS1_k127_7370712_2 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 317.0
TLS1_k127_7370712_3 CHAD - - - 0.000000000000000000000000000000000000000000001139 178.0
TLS1_k127_7370712_4 transcriptional regulator - - - 0.000000000000000000000000000003521 133.0
TLS1_k127_7382284_0 CoA-transferase family III K18313 - 2.8.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 306.0
TLS1_k127_7382284_1 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000003485 231.0
TLS1_k127_7408511_0 phosphogluconate dehydrogenase (decarboxylating) activity K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000001293 191.0
TLS1_k127_7408511_1 Redoxin K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.000000000000000000000000000000000000000000000000124 190.0
TLS1_k127_7408511_2 Histidine kinase - - - 0.0000000000000000000000002253 120.0
TLS1_k127_7408511_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000005127 113.0
TLS1_k127_7408511_4 integral membrane protein - - - 0.000007753 57.0
TLS1_k127_7410161_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 616.0
TLS1_k127_7410161_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 328.0
TLS1_k127_7410161_2 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000006015 218.0
TLS1_k127_7410161_3 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000009324 200.0
TLS1_k127_7410161_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000008207 188.0
TLS1_k127_7410161_5 AsnC family - - - 0.0000000000000000000000000000233 118.0
TLS1_k127_7410161_6 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000003445 121.0
TLS1_k127_7410161_7 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000001624 87.0
TLS1_k127_7410161_8 Cold shock K03704 - - 0.000000006475 63.0
TLS1_k127_7414432_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 357.0
TLS1_k127_7414432_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000004256 247.0
TLS1_k127_7414432_2 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000003188 214.0
TLS1_k127_7414432_3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000000000000003877 143.0
TLS1_k127_7414432_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000000005856 114.0
TLS1_k127_7414432_5 HNH endonuclease - - - 0.000000000000009294 85.0
TLS1_k127_741577_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.303e-208 658.0
TLS1_k127_741577_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 419.0
TLS1_k127_741577_2 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 372.0
TLS1_k127_741577_3 glyoxalase III activity - - - 0.0000000000007132 74.0
TLS1_k127_7443242_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 582.0
TLS1_k127_7443242_1 Belongs to the binding-protein-dependent transport system permease family K10544 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 547.0
TLS1_k127_7443242_2 ABC transporter substrate-binding protein K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 421.0
TLS1_k127_7443242_3 ABC transporter, ATP-binding protein K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 353.0
TLS1_k127_7443242_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000395 230.0
TLS1_k127_7443242_5 Transcriptional regulator sugar kinase - - - 0.0000000000000000000000000000000000003364 147.0
TLS1_k127_7457249_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 302.0
TLS1_k127_7457249_1 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 296.0
TLS1_k127_7457249_2 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000006021 260.0
TLS1_k127_7457249_3 Alpha beta hydrolase - - - 0.0000000000000007711 79.0
TLS1_k127_7461104_0 Peptidase family M41 - - - 7.667e-232 736.0
TLS1_k127_7463809_0 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 401.0
TLS1_k127_7463809_1 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000002191 201.0
TLS1_k127_7465263_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 419.0
TLS1_k127_7465263_1 Penicillin binding protein transpeptidase domain K05364 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 354.0
TLS1_k127_7465263_2 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 317.0
TLS1_k127_7465263_3 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002155 293.0
TLS1_k127_7465263_4 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000009338 189.0
TLS1_k127_7465263_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000001767 115.0
TLS1_k127_7465263_6 Protein of unknown function (DUF2662) - - - 0.000000000000000005441 93.0
TLS1_k127_7465263_7 histone H2A K63-linked ubiquitination K02283 - - 0.000000000000000008451 94.0
TLS1_k127_7465717_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 593.0
TLS1_k127_7465717_1 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 504.0
TLS1_k127_7465717_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 357.0
TLS1_k127_7465717_3 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004651 255.0
TLS1_k127_7465717_4 PFAM oxidoreductase molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000006887 207.0
TLS1_k127_7465717_5 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000002117 154.0
TLS1_k127_7465717_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000002763 91.0
TLS1_k127_7465717_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000003185 87.0
TLS1_k127_7465717_8 Mo-molybdopterin cofactor metabolic process K03636,K21142 - 2.8.1.12 0.000000000001288 78.0
TLS1_k127_7465717_9 Alpha beta hydrolase - - - 0.000000008488 66.0
TLS1_k127_7467647_0 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 333.0
TLS1_k127_7467647_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000002486 165.0
TLS1_k127_7467647_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000002131 95.0
TLS1_k127_7471588_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.0 1567.0
TLS1_k127_7471588_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 609.0
TLS1_k127_7482554_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 408.0
TLS1_k127_7482554_1 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000001326 217.0
TLS1_k127_7482554_2 Belongs to the TPP enzyme family K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 0.000000000000000001408 87.0
TLS1_k127_7497134_0 NADH flavin oxidoreductase NADH oxidase K00354,K09461 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 1.14.13.40,1.6.99.1 1.245e-281 885.0
TLS1_k127_7513528_0 Clp domain protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1150.0
TLS1_k127_7513528_1 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 503.0
TLS1_k127_7513528_2 ABC transporter related K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 399.0
TLS1_k127_7513528_3 ABC transporter substrate-binding protein PnrA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 340.0
TLS1_k127_7513528_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000003724 243.0
TLS1_k127_7513528_5 queuosine salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000002393 227.0
TLS1_k127_7513528_6 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000005262 212.0
TLS1_k127_7513528_7 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.00000000000001881 82.0
TLS1_k127_7526586_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.637e-236 738.0
TLS1_k127_7526586_1 Arginase family - - - 0.0000000000000000000000000000000000000000000000000000003158 204.0
TLS1_k127_7526586_2 - - - - 0.000000000000002107 81.0
TLS1_k127_7580075_0 phosphorylase K00688 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000002714 234.0
TLS1_k127_7589422_0 AMP-binding enzyme C-terminal domain K00666 - - 4.323e-319 984.0
TLS1_k127_7589422_1 Transposase - - - 0.0000000000000000000000000000000003824 131.0
TLS1_k127_7589422_2 Integrase catalytic - - - 0.00000000000000000002584 98.0
TLS1_k127_7589422_3 Transposase - - - 0.00000000001283 72.0
TLS1_k127_7589422_4 HNH nucleases - - - 0.0002984 50.0
TLS1_k127_7589429_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 355.0
TLS1_k127_7589429_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000007439 73.0
TLS1_k127_7589429_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000002365 78.0
TLS1_k127_7637572_0 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 476.0
TLS1_k127_7637572_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 366.0
TLS1_k127_7637572_2 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 332.0
TLS1_k127_7637572_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000001727 256.0
TLS1_k127_7649579_0 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000007571 245.0
TLS1_k127_7649579_1 nitric oxide dioxygenase activity K00528,K05784 GO:0000166,GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004324,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006000,GO:0006001,GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0016043,GO:0016052,GO:0016226,GO:0016491,GO:0016730,GO:0016731,GO:0019318,GO:0019320,GO:0022607,GO:0031163,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0055114,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901575,GO:1901700 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000002404 233.0
TLS1_k127_7649579_2 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000001865 136.0
TLS1_k127_7680586_0 Binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 376.0
TLS1_k127_7680586_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 343.0
TLS1_k127_7680586_2 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000003106 221.0
TLS1_k127_7680586_3 - - - - 0.0000000009068 67.0
TLS1_k127_7719436_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 299.0
TLS1_k127_7719436_1 Belongs to the NUDIX hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000001196 207.0
TLS1_k127_7719436_2 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000001969 138.0
TLS1_k127_7719436_3 ABC transporter transmembrane region K02021,K06147,K16786,K16787 - - 0.00000000000000302 76.0
TLS1_k127_7739559_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.209e-202 647.0
TLS1_k127_7739559_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 322.0
TLS1_k127_7739559_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000001324 160.0
TLS1_k127_7762333_0 PFAM peptidase C45 acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase K19200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005532 267.0
TLS1_k127_7762333_1 Acetyltransferase (GNAT) family - - - 0.000000000000000003111 97.0
TLS1_k127_7775849_0 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 475.0
TLS1_k127_7775849_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000001738 166.0
TLS1_k127_7775849_2 carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000001592 143.0
TLS1_k127_7789441_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 413.0
TLS1_k127_7789441_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000002159 120.0
TLS1_k127_7789441_2 NADH flavin oxidoreductase NADH oxidase K00354,K09461 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 1.14.13.40,1.6.99.1 0.000000006681 57.0
TLS1_k127_7804172_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 5.328e-226 711.0
TLS1_k127_7804172_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000003827 209.0
TLS1_k127_7804172_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000111 208.0
TLS1_k127_7849353_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 317.0
TLS1_k127_7849353_1 amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000001737 228.0
TLS1_k127_7849353_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000001931 83.0
TLS1_k127_7852097_0 ATPases associated with a variety of cellular activities K15555 - - 0.000000000000000000000000000000000000000000000002062 182.0
TLS1_k127_7852097_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000004575 176.0
TLS1_k127_7852097_2 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000002499 112.0
TLS1_k127_7935135_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.000000000000000000000000000000000000000000000000000000002029 208.0
TLS1_k127_7935135_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000003631 135.0
TLS1_k127_7935135_2 peptidase - - - 0.000001078 59.0
TLS1_k127_7945889_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 445.0
TLS1_k127_7945889_1 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000005006 196.0
TLS1_k127_7945889_2 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000006952 158.0
TLS1_k127_7952743_0 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 2.233e-245 778.0
TLS1_k127_7952743_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 552.0
TLS1_k127_7952743_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 380.0
TLS1_k127_7952743_3 Phosphoserine phosphatase K01079 GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 375.0
TLS1_k127_7952743_4 Phenazine biosynthesis protein PhzF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 360.0
TLS1_k127_7952743_5 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000007238 264.0
TLS1_k127_7952743_6 Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor K00845,K00886 - 2.7.1.2,2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000002382 246.0
TLS1_k127_7962070_0 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 318.0
TLS1_k127_7962070_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.0000000000000000000000000000000218 132.0
TLS1_k127_8014855_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 337.0
TLS1_k127_8014855_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000004021 164.0
TLS1_k127_8014855_2 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000001904 119.0
TLS1_k127_8014855_3 phosphoglycerate mutase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000001131 114.0
TLS1_k127_8014855_4 Protein of unknown function (DUF3040) - - - 0.0002768 48.0
TLS1_k127_803531_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001818 278.0
TLS1_k127_803531_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000004064 175.0
TLS1_k127_803531_2 Stage II sporulation protein - - - 0.00000001642 64.0
TLS1_k127_8066769_0 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000923 250.0
TLS1_k127_8066769_1 Low molecular weight phosphatase family - - - 0.000000000000000000000000000000000000000000000000001513 190.0
TLS1_k127_837861_0 typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000007847 201.0
TLS1_k127_837861_1 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000003131 133.0
TLS1_k127_856172_0 pfam abc K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 364.0
TLS1_k127_856172_1 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 348.0
TLS1_k127_856172_2 Belongs to the peptidase S16 family K07177 - - 0.000000000000000000000000000000000000000000000000000065 201.0
TLS1_k127_856172_3 BioY family K03523 - - 0.00000000000000000000000000000000000000000002749 168.0
TLS1_k127_856172_4 regulation of cell shape K04074 - - 0.000003793 57.0
TLS1_k127_860425_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000003369 209.0
TLS1_k127_860425_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000001394 163.0
TLS1_k127_860425_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000007605 155.0
TLS1_k127_860425_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000005436 144.0
TLS1_k127_860425_4 Bulb-type mannose-specific lectin - - - 0.000004012 53.0
TLS1_k127_860425_5 membrane protein TerC - - - 0.0007204 44.0
TLS1_k127_902990_0 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000001854 207.0
TLS1_k127_902990_1 Bacterial extracellular solute-binding protein - - - 0.0006466 48.0
TLS1_k127_907647_0 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 560.0
TLS1_k127_907647_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 401.0
TLS1_k127_907647_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 286.0
TLS1_k127_907647_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002416 241.0
TLS1_k127_907647_4 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000002428 191.0
TLS1_k127_907647_5 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.0000000000000000000000000000000001242 136.0
TLS1_k127_918200_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 507.0
TLS1_k127_918200_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006958 229.0
TLS1_k127_918200_2 Alpha/beta hydrolase family - - - 0.0000004489 52.0
TLS1_k127_92203_0 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 346.0
TLS1_k127_92203_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003543 280.0
TLS1_k127_92203_2 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000001949 245.0
TLS1_k127_92203_3 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001239 241.0
TLS1_k127_92203_4 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00000000000000000000000000000000000000000005776 167.0
TLS1_k127_92203_5 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000008903 158.0
TLS1_k127_92203_6 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000589 156.0
TLS1_k127_92203_7 NifU-like domain K07400 - - 0.0000000000000000000000000000000001213 150.0
TLS1_k127_92203_8 PFAM blue (type 1) copper domain protein - - - 0.00002021 52.0
TLS1_k127_93376_0 Protein of unknown function (DUF993) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 471.0
TLS1_k127_93376_1 F420-dependent oxidoreductase, Rv1855c family - - - 0.00000000000000000000000000000000000000000000000000000000000000008369 228.0
TLS1_k127_93376_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000006971 195.0
TLS1_k127_98794_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 431.0
TLS1_k127_98794_1 Type II/IV secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 313.0
TLS1_k127_98794_2 acetyltransferase - - - 0.0000000000000000000000000000000004234 136.0
TLS1_k127_98794_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000004633 105.0
TLS1_k127_98794_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.0000000000000000000001338 107.0
TLS1_k127_98794_5 Helix-turn-helix domain - - - 0.000000000000000007814 93.0
TLS1_k127_997636_0 RNase_H superfamily - - - 0.00000000000000000000000000000000000000000002072 177.0
TLS1_k127_997636_1 Acetyltransferase K06975 - - 0.00000000000000000000002687 104.0
TLS1_k127_997636_2 Thioesterase-like superfamily K07107 - - 0.00000000000000000000009577 103.0