Overview

ID MAG03991
Name TLS2_bin.24
Sample SMP0104
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_C
Class Deferrisomatia
Order Deferrisomatales
Family JACRMM01
Genus JBFLZB01
Species
Assembly information
Completeness (%) 78.96
Contamination (%) 2.03
GC content (%) 70.0
N50 (bp) 6,340
Genome size (bp) 2,474,401

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2238

Gene name Description KEGG GOs EC E-value Score Sequence
TLS2_k127_1012221_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.729e-289 899.0
TLS2_k127_1012221_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 565.0
TLS2_k127_1012221_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 528.0
TLS2_k127_1012221_3 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000426 194.0
TLS2_k127_1012221_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000001019 105.0
TLS2_k127_1012221_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000001405 91.0
TLS2_k127_1012221_6 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001808 78.0
TLS2_k127_1012221_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000006988 68.0
TLS2_k127_1012752_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2e-322 995.0
TLS2_k127_1012752_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 533.0
TLS2_k127_1012752_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 342.0
TLS2_k127_1012752_3 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001086 266.0
TLS2_k127_1012752_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002831 253.0
TLS2_k127_1012752_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000001108 169.0
TLS2_k127_1012752_6 protein secretion K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000004255 102.0
TLS2_k127_1012752_7 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000002447 83.0
TLS2_k127_1012752_8 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000003048 61.0
TLS2_k127_1036796_0 HI0933-like protein K00313 - - 7.536e-211 687.0
TLS2_k127_1036796_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 1.491e-195 619.0
TLS2_k127_1036796_2 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003886 290.0
TLS2_k127_1036796_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000002551 234.0
TLS2_k127_1036796_4 Could be a 3Fe-4S cluster-containing protein K03855 - - 0.00000000000000000000000000000000000005266 156.0
TLS2_k127_1036796_5 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000006727 101.0
TLS2_k127_105803_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 612.0
TLS2_k127_105803_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 329.0
TLS2_k127_105803_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000001741 204.0
TLS2_k127_105803_3 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000003805 186.0
TLS2_k127_105803_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K08365,K13640,K18997,K19057 - - 0.0000000000000000000000000000000001415 136.0
TLS2_k127_1058911_0 VWA containing CoxE family protein K09989 - - 1.695e-194 627.0
TLS2_k127_1058911_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 475.0
TLS2_k127_1058911_2 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 473.0
TLS2_k127_1058911_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 396.0
TLS2_k127_1058911_4 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 340.0
TLS2_k127_1058911_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 332.0
TLS2_k127_1058911_6 PFAM metal-dependent phosphohydrolase HD sub - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 287.0
TLS2_k127_1058911_7 - - - - 0.00000000000000000000000000007321 117.0
TLS2_k127_1058911_8 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.00000000000000000000000008188 107.0
TLS2_k127_1059054_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1302.0
TLS2_k127_1059054_1 Type II and III secretion system protein K02666 - - 2.41e-287 908.0
TLS2_k127_1059054_10 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000011 213.0
TLS2_k127_1059054_11 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000005255 184.0
TLS2_k127_1059054_12 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000001248 165.0
TLS2_k127_1059054_13 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000001114 151.0
TLS2_k127_1059054_14 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000000001142 145.0
TLS2_k127_1059054_16 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000006296 138.0
TLS2_k127_1059054_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 594.0
TLS2_k127_1059054_3 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 567.0
TLS2_k127_1059054_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 424.0
TLS2_k127_1059054_5 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 334.0
TLS2_k127_1059054_6 PFAM Pilus assembly protein PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001051 276.0
TLS2_k127_1059054_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000002665 255.0
TLS2_k127_1059054_8 PFAM Fimbrial assembly family protein K02663 - - 0.0000000000000000000000000000000000000000000000000000000000000000007655 234.0
TLS2_k127_1059054_9 SAM-dependent RNA methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000002023 225.0
TLS2_k127_1071220_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1695.0
TLS2_k127_1071220_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5.117e-309 959.0
TLS2_k127_1071220_2 Beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 541.0
TLS2_k127_1071220_3 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 371.0
TLS2_k127_1071220_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000009367 213.0
TLS2_k127_1071220_6 Protein of unknown function (DUF4242) - - - 0.00000000006658 69.0
TLS2_k127_1071220_7 FR47-like protein - - - 0.0003961 46.0
TLS2_k127_1072544_0 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 6.061e-318 978.0
TLS2_k127_1072544_1 glutamate synthase - - - 7.851e-204 642.0
TLS2_k127_1072544_10 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 300.0
TLS2_k127_1072544_11 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 288.0
TLS2_k127_1072544_12 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000000465 149.0
TLS2_k127_1072544_13 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000001915 119.0
TLS2_k127_1072544_2 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 1.197e-200 632.0
TLS2_k127_1072544_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 597.0
TLS2_k127_1072544_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 506.0
TLS2_k127_1072544_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 444.0
TLS2_k127_1072544_6 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 379.0
TLS2_k127_1072544_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 343.0
TLS2_k127_1072544_8 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 326.0
TLS2_k127_1072544_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 323.0
TLS2_k127_1093106_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.0 1084.0
TLS2_k127_1093106_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 2.628e-226 706.0
TLS2_k127_1093106_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 449.0
TLS2_k127_1093106_3 Thioesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000009806 177.0
TLS2_k127_1093106_4 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000003308 121.0
TLS2_k127_1093106_5 isomerase activity K01821 - 5.3.2.6 0.000000000000000000000008757 102.0
TLS2_k127_1093106_6 - - - - 0.000000000005857 70.0
TLS2_k127_1094331_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0 1039.0
TLS2_k127_1094331_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 585.0
TLS2_k127_1094331_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 513.0
TLS2_k127_1094331_3 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 519.0
TLS2_k127_1094331_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 433.0
TLS2_k127_1094331_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 325.0
TLS2_k127_1094331_6 PFAM Peptidase M22, glycoprotease K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000001613 222.0
TLS2_k127_1094331_7 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000008403 151.0
TLS2_k127_115690_0 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 5.744e-256 823.0
TLS2_k127_115690_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 2.223e-209 676.0
TLS2_k127_115690_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 402.0
TLS2_k127_115690_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001562 285.0
TLS2_k127_115888_0 PFAM Cys Met metabolism K01740 - 2.5.1.49 3.157e-231 721.0
TLS2_k127_115888_1 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000001477 148.0
TLS2_k127_1162043_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 552.0
TLS2_k127_1162043_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001001 230.0
TLS2_k127_1162043_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000006271 181.0
TLS2_k127_1167495_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0 1142.0
TLS2_k127_1167495_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 1.772e-285 886.0
TLS2_k127_1167495_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000004834 96.0
TLS2_k127_116931_0 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 480.0
TLS2_k127_116931_1 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 413.0
TLS2_k127_116931_2 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 301.0
TLS2_k127_116931_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001118 250.0
TLS2_k127_116931_4 Protein of unknown function (DUF2889) - - - 0.0000000000000000000000000000000000000000000000000000000000008586 213.0
TLS2_k127_1170650_0 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 483.0
TLS2_k127_1170650_1 exonuclease, RdgC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000234 286.0
TLS2_k127_1170650_2 May be involved in recombination - - - 0.0000000000000000000000000000000000000000000000000000000009801 215.0
TLS2_k127_1170650_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000004324 191.0
TLS2_k127_1170650_4 AAA domain (Cdc48 subfamily) K02481,K07712,K07713 - - 0.00000000000000001443 87.0
TLS2_k127_1172608_0 Na+/Pi-cotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 616.0
TLS2_k127_1172608_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 574.0
TLS2_k127_1172608_2 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 317.0
TLS2_k127_1172608_3 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001364 280.0
TLS2_k127_1172608_4 Domain of unknown function (DUF4388) - - - 0.000000006268 62.0
TLS2_k127_1176318_0 4Fe-4S dicluster domain - - - 1.912e-220 703.0
TLS2_k127_1176318_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 529.0
TLS2_k127_1176318_2 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 389.0
TLS2_k127_1176318_3 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 355.0
TLS2_k127_1190068_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.083e-276 854.0
TLS2_k127_1190068_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.102e-272 844.0
TLS2_k127_1190068_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000005013 184.0
TLS2_k127_1190068_11 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000009973 186.0
TLS2_k127_1190068_13 CBS domain - - - 0.000000000000000000000000002664 118.0
TLS2_k127_1190068_14 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000002273 56.0
TLS2_k127_1190068_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 6.195e-215 676.0
TLS2_k127_1190068_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 7.046e-201 631.0
TLS2_k127_1190068_4 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 487.0
TLS2_k127_1190068_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 466.0
TLS2_k127_1190068_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002442 282.0
TLS2_k127_1190068_7 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008503 250.0
TLS2_k127_1190068_8 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000001458 210.0
TLS2_k127_1190068_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000001167 196.0
TLS2_k127_1195548_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 389.0
TLS2_k127_1195548_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000005094 232.0
TLS2_k127_1195548_2 cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000374 190.0
TLS2_k127_1207311_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.965e-257 804.0
TLS2_k127_1207311_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 619.0
TLS2_k127_1207311_2 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 296.0
TLS2_k127_1207311_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000002691 218.0
TLS2_k127_1207311_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000001352 160.0
TLS2_k127_1225168_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 396.0
TLS2_k127_1225168_1 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000002732 213.0
TLS2_k127_1225168_2 PFAM Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000002556 186.0
TLS2_k127_1225168_3 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000000000000281 150.0
TLS2_k127_1225168_4 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000004936 101.0
TLS2_k127_1227873_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.043e-284 881.0
TLS2_k127_1227873_1 HI0933-like protein K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 593.0
TLS2_k127_1227873_2 electron transfer flavoprotein, alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 356.0
TLS2_k127_1227873_3 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000008086 215.0
TLS2_k127_1227873_4 Could be a 3Fe-4S cluster-containing protein K03855 - - 0.000000000000000000000000000000000000000000004704 164.0
TLS2_k127_1227873_5 Electron transfer flavoprotein - - - 0.00000004475 55.0
TLS2_k127_1248514_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00033,K00616,K01810,K08300,K13810 - 1.1.1.343,1.1.1.44,2.2.1.2,3.1.26.12,5.3.1.9 1.758e-286 907.0
TLS2_k127_1248514_1 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000001957 233.0
TLS2_k127_1248514_2 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000008582 227.0
TLS2_k127_1248514_3 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000001696 163.0
TLS2_k127_1248514_4 pfam abc K02003 - - 0.00000000000261 68.0
TLS2_k127_1248514_5 GtrA-like protein - - - 0.000000008821 64.0
TLS2_k127_1248514_6 Late competence development protein ComFB K02241 - - 0.00005287 50.0
TLS2_k127_1258010_0 PFAM FAD linked oxidase domain protein K00004,K00102,K00104 GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.1.1.303,1.1.1.4,1.1.2.4,1.1.3.15 3.876e-264 817.0
TLS2_k127_1258010_1 PFAM AMP-dependent synthetase and ligase K01895,K08295 - 6.2.1.1,6.2.1.32 8.863e-248 779.0
TLS2_k127_1258010_10 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000005035 205.0
TLS2_k127_1258010_11 Helix-turn-helix domain - - - 0.000001389 53.0
TLS2_k127_1258010_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 4.088e-230 719.0
TLS2_k127_1258010_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 578.0
TLS2_k127_1258010_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 411.0
TLS2_k127_1258010_5 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 353.0
TLS2_k127_1258010_6 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 318.0
TLS2_k127_1258010_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 330.0
TLS2_k127_1258010_8 transcriptional K05799,K11474 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000006742 251.0
TLS2_k127_1258010_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000001607 216.0
TLS2_k127_1280574_0 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 617.0
TLS2_k127_1280574_1 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 304.0
TLS2_k127_1280574_2 Type IV leader peptidase family K02278 - 3.4.23.43 0.000000000000000000000000000000000000000000001896 171.0
TLS2_k127_1290868_0 CBS domain containing protein K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 580.0
TLS2_k127_1290868_1 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 440.0
TLS2_k127_1290868_2 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 299.0
TLS2_k127_1290868_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000995 194.0
TLS2_k127_1290868_4 cyclic nucleotide binding K01734 - 4.2.3.3 0.00000000000000000000000000000000000000003828 174.0
TLS2_k127_1290868_5 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K04562 - - 0.0000000000002372 81.0
TLS2_k127_1299948_0 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 530.0
TLS2_k127_1299948_1 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001415 289.0
TLS2_k127_1299948_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000001683 182.0
TLS2_k127_1299948_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000006321 159.0
TLS2_k127_1325270_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.147e-214 683.0
TLS2_k127_1325270_1 Cys Met metabolism K01760 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 587.0
TLS2_k127_1325270_2 Cys Met metabolism K01739,K01760 - 2.5.1.48,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 545.0
TLS2_k127_1325270_3 Nitrite and sulphite reductase 4Fe-4S domain K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 386.0
TLS2_k127_1325270_4 protein-disulfide reductase activity - - - 0.00000000000000000000000000000000003219 141.0
TLS2_k127_1325270_6 PFAM GCN5-related N-acetyltransferase - - - 0.0000000004252 68.0
TLS2_k127_1325386_0 glutamate--cysteine ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 444.0
TLS2_k127_1325386_1 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000008873 194.0
TLS2_k127_1325386_2 In Escherichia coli this enzyme appears to be an NAD NADP -dependent succinate semialdehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000008902 55.0
TLS2_k127_133248_0 methylated-DNA- protein -cysteine S-methyltransferase K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 306.0
TLS2_k127_1333585_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 3.438e-222 707.0
TLS2_k127_1333585_1 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 278.0
TLS2_k127_1333585_2 PFAM Cytochrome C - - - 0.000000000000000000000000000000002059 141.0
TLS2_k127_136863_0 PFAM Aldehyde ferredoxin oxidoreductase - - - 2.427e-255 799.0
TLS2_k127_136863_1 ABC transporter transmembrane region - - - 2.41e-215 684.0
TLS2_k127_136863_2 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003117 240.0
TLS2_k127_1397707_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 482.0
TLS2_k127_1397707_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 431.0
TLS2_k127_1397707_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 417.0
TLS2_k127_1397707_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 334.0
TLS2_k127_1397707_4 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006258 290.0
TLS2_k127_1397707_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000002534 281.0
TLS2_k127_1399820_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.313e-281 877.0
TLS2_k127_1399820_1 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 3.935e-215 677.0
TLS2_k127_1399820_2 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 520.0
TLS2_k127_1399820_3 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 440.0
TLS2_k127_1399820_4 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 430.0
TLS2_k127_1399820_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 421.0
TLS2_k127_1399820_6 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 370.0
TLS2_k127_1399820_7 SMART Chromosomal replication initiator DnaA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 331.0
TLS2_k127_1407089_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.598e-314 970.0
TLS2_k127_1407089_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 388.0
TLS2_k127_1413713_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1162.0
TLS2_k127_1413713_1 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000002744 219.0
TLS2_k127_1421552_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1008.0
TLS2_k127_1421552_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.595e-265 830.0
TLS2_k127_1421552_2 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 631.0
TLS2_k127_1435486_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 9.561e-205 642.0
TLS2_k127_1435486_1 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 427.0
TLS2_k127_1435486_2 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 320.0
TLS2_k127_1435486_3 response regulator K02479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007903 291.0
TLS2_k127_1435486_4 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001714 228.0
TLS2_k127_1446227_0 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 623.0
TLS2_k127_1446227_1 ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 464.0
TLS2_k127_1446227_2 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 465.0
TLS2_k127_1446227_3 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 365.0
TLS2_k127_1446227_4 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.00000000000000415 76.0
TLS2_k127_1456705_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 543.0
TLS2_k127_1456705_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 514.0
TLS2_k127_1456705_2 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 424.0
TLS2_k127_1456705_3 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 361.0
TLS2_k127_1456705_4 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001309 244.0
TLS2_k127_1482363_0 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 444.0
TLS2_k127_1482363_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003588 277.0
TLS2_k127_1482363_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000388 262.0
TLS2_k127_1482363_3 PIN domain - - - 0.000000000000000000000000000000000000000000000000002616 189.0
TLS2_k127_1482363_5 Response regulator receiver - - - 0.000000000000002284 84.0
TLS2_k127_152969_0 PFAM Carbamoyl-phosphate synthase L chain K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 589.0
TLS2_k127_152969_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 546.0
TLS2_k127_152969_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001233 268.0
TLS2_k127_152969_3 DNA mediated transformation K04096 - - 0.00000000000000000000000000000000000000000000001358 178.0
TLS2_k127_152969_5 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000006103 106.0
TLS2_k127_152969_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000003472 105.0
TLS2_k127_152969_7 AhpC/TSA family K03564 - 1.11.1.15 0.000000000533 64.0
TLS2_k127_1533870_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 555.0
TLS2_k127_1533870_1 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 486.0
TLS2_k127_156426_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 9.133e-308 969.0
TLS2_k127_156426_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.577e-275 880.0
TLS2_k127_156426_2 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 410.0
TLS2_k127_156426_3 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 412.0
TLS2_k127_156426_4 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 358.0
TLS2_k127_156426_5 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001707 297.0
TLS2_k127_156426_6 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000001286 240.0
TLS2_k127_156426_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000003861 85.0
TLS2_k127_156426_8 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.00000000000000007657 83.0
TLS2_k127_1566029_0 protein conserved in bacteria K05805 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000002183 203.0
TLS2_k127_1566029_1 Iron-regulated membrane protein - - - 0.000000000000000000000000000000000000000000000001225 186.0
TLS2_k127_1566029_2 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000002402 175.0
TLS2_k127_1567913_0 Thiamine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 495.0
TLS2_k127_1567913_1 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 488.0
TLS2_k127_1567913_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009376 280.0
TLS2_k127_1567913_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001453 271.0
TLS2_k127_1567913_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000009892 265.0
TLS2_k127_1567913_5 SMART helix-turn-helix domain protein K15539 - - 0.0000000000000000000000000000000000000000000000000003227 194.0
TLS2_k127_1567913_6 phosphorelay signal transduction system - - - 0.000000000000000000000000005552 115.0
TLS2_k127_1585984_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000002547 225.0
TLS2_k127_1585984_1 PFAM Peptidase M22, glycoprotease - - - 0.00000000000000000000005821 104.0
TLS2_k127_1599903_0 PFAM GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 412.0
TLS2_k127_1599903_1 Dodecin K09165 - - 0.00000000000000000000000003893 111.0
TLS2_k127_1615148_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.842e-313 967.0
TLS2_k127_1615148_1 FAD binding domain - - - 5.979e-237 737.0
TLS2_k127_1615148_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.943e-199 626.0
TLS2_k127_1615148_3 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 381.0
TLS2_k127_1615148_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001133 272.0
TLS2_k127_1615148_5 PFAM Cysteine-rich region, CCG K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0006651 42.0
TLS2_k127_1619498_0 TonB dependent receptor K16092 - - 3.604e-216 699.0
TLS2_k127_1619498_1 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 446.0
TLS2_k127_1619498_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 347.0
TLS2_k127_1619498_3 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000003099 193.0
TLS2_k127_1619498_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000003003 175.0
TLS2_k127_1623137_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.218e-243 764.0
TLS2_k127_1623137_1 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 368.0
TLS2_k127_1623137_2 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 311.0
TLS2_k127_163524_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.139e-218 684.0
TLS2_k127_163524_1 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 407.0
TLS2_k127_163524_2 Cobalamin (Vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
TLS2_k127_163524_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 302.0
TLS2_k127_1640033_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1006.0
TLS2_k127_1640033_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.253e-219 686.0
TLS2_k127_1640033_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000001758 246.0
TLS2_k127_1640033_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000936 224.0
TLS2_k127_1644596_0 LUD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 312.0
TLS2_k127_1644596_1 hydrolases or acyltransferases, alpha beta hydrolase superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 293.0
TLS2_k127_1644596_2 Lactate utilization protein C K00782 - - 0.000000000000001207 79.0
TLS2_k127_1646049_0 alpha,alpha-trehalase activity K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 609.0
TLS2_k127_1646049_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 612.0
TLS2_k127_1646049_2 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 402.0
TLS2_k127_1648903_0 transposase or invertase - - - 0.000001954 56.0
TLS2_k127_1648903_1 Domain of unknown function (DUF4351) - - - 0.00003486 57.0
TLS2_k127_1648903_2 Immune inhibitor A peptidase M6 K09607 - - 0.0007058 50.0
TLS2_k127_1656235_0 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412 - 3.6.3.14 4.006e-233 729.0
TLS2_k127_1656235_1 flagellar motor switch protein FliG K02410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 555.0
TLS2_k127_1656235_2 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 388.0
TLS2_k127_1656235_3 PFAM Flagellar assembly protein FliH K02411 - - 0.0000000000000000000000000000000000000000000000000000002628 204.0
TLS2_k127_1666128_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 544.0
TLS2_k127_1666128_1 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 306.0
TLS2_k127_1666128_2 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000000000000000006566 183.0
TLS2_k127_1671557_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 494.0
TLS2_k127_1671557_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 418.0
TLS2_k127_1671557_2 PFAM AMP-dependent synthetase and ligase - - - 0.000000000405 62.0
TLS2_k127_1693553_0 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000003887 143.0
TLS2_k127_1695547_0 Peptidase M16 - - - 6.462e-217 689.0
TLS2_k127_1695547_1 - - - - 1.377e-202 651.0
TLS2_k127_1695547_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 501.0
TLS2_k127_1695547_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 421.0
TLS2_k127_1695547_4 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 420.0
TLS2_k127_1695547_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005799 255.0
TLS2_k127_1695547_6 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000932 251.0
TLS2_k127_1695547_7 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000001522 254.0
TLS2_k127_1695547_8 PAP2 superfamily K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000006497 216.0
TLS2_k127_1695547_9 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00005727 54.0
TLS2_k127_1702236_0 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 387.0
TLS2_k127_1702236_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 307.0
TLS2_k127_1702236_2 - - - - 0.00000000001189 76.0
TLS2_k127_1726144_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 5.019e-236 757.0
TLS2_k127_1726144_1 Sigma-70 factor, region 1.1 K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 549.0
TLS2_k127_1726144_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 399.0
TLS2_k127_1726144_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431,K12251 - 3.5.1.53,3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 378.0
TLS2_k127_1726144_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 303.0
TLS2_k127_1726144_5 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000005935 145.0
TLS2_k127_1726144_6 Sporulation related domain - - - 0.00000000000000000000000000000000005025 144.0
TLS2_k127_1726144_7 - - - - 0.000000000000000000000000000009562 124.0
TLS2_k127_1726144_9 PFAM Colicin V production protein K03558 - - 0.0000755 52.0
TLS2_k127_1742673_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 299.0
TLS2_k127_1742673_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - 0.00000000000000000000000000000000000000000000000000000000000000000434 243.0
TLS2_k127_1742673_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000001816 144.0
TLS2_k127_1742673_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000007085 145.0
TLS2_k127_1742673_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000001871 115.0
TLS2_k127_1742673_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000000000000000000002694 110.0
TLS2_k127_1747704_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 339.0
TLS2_k127_1747704_1 ATPase involved in DNA repair K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000008538 233.0
TLS2_k127_1747704_3 - - - - 0.00000000000000000000000000000000003456 154.0
TLS2_k127_1818567_0 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 485.0
TLS2_k127_1818567_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 460.0
TLS2_k127_1818567_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 451.0
TLS2_k127_1818567_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000001238 117.0
TLS2_k127_1847272_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 477.0
TLS2_k127_1847272_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000002138 211.0
TLS2_k127_1847272_2 Nitroreductase family - - - 0.00000000000000000000000000000000000009643 148.0
TLS2_k127_1855898_0 ATP-dependent helicase K03579 - 3.6.4.13 9.91e-290 921.0
TLS2_k127_1855898_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 5.02e-257 806.0
TLS2_k127_1855898_2 Domain of unknown function (DUF2088) - - - 3.344e-215 680.0
TLS2_k127_1855898_3 SMART Metal-dependent phosphohydrolase, HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 570.0
TLS2_k127_1855898_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006218 255.0
TLS2_k127_1855898_5 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000002495 243.0
TLS2_k127_1855898_6 BioY family K03523 - - 0.00000000000000000000000000000006804 132.0
TLS2_k127_1855898_7 GYD domain - - - 0.0000000000000001594 84.0
TLS2_k127_1855898_8 Psort location Cytoplasmic, score 8.87 K00180 - 1.2.7.8 0.0000000008541 72.0
TLS2_k127_1855898_9 Mut7-C ubiquitin K09122 - - 0.000009176 56.0
TLS2_k127_186472_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 7.727e-243 771.0
TLS2_k127_186472_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000004103 243.0
TLS2_k127_186472_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000004014 171.0
TLS2_k127_186472_4 methyltransferase - - - 0.0000000000000000002331 90.0
TLS2_k127_1872364_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002866 298.0
TLS2_k127_1872364_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002021 246.0
TLS2_k127_1872364_2 cellulase activity K12287 - - 0.00000000000000000000000000000000003464 152.0
TLS2_k127_1872364_3 Domain of unknown function (DUF1844) - - - 0.000000000000000000000000003217 126.0
TLS2_k127_1872364_4 Right handed beta helix region - - - 0.000009281 58.0
TLS2_k127_1901040_0 peptidase M48, Ste24p - - - 2.024e-240 760.0
TLS2_k127_1901040_1 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 322.0
TLS2_k127_1901268_0 Domain of unknown function DUF87 - - - 9.388e-232 727.0
TLS2_k127_1901268_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 463.0
TLS2_k127_1901268_10 FMN_bind K00348 - 1.6.5.8 0.000000000000000000000002554 119.0
TLS2_k127_1901268_11 Thiamine-binding protein - - - 0.00000000000003626 87.0
TLS2_k127_1901268_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 418.0
TLS2_k127_1901268_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 314.0
TLS2_k127_1901268_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 322.0
TLS2_k127_1901268_5 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 289.0
TLS2_k127_1901268_6 Alcohol dehydrogenase GroES-like domain K00055 - 1.1.1.90 0.0000000000000000000000000000000000000000000000000000000000000000004192 234.0
TLS2_k127_1901268_7 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000004984 216.0
TLS2_k127_1901268_8 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000000000000000000000000000005455 214.0
TLS2_k127_1901268_9 COGs COG4087 Soluble P-type ATPase - - - 0.000000000000000000000000000000000000000000000000000002553 195.0
TLS2_k127_191562_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.035e-251 784.0
TLS2_k127_191562_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.386e-242 759.0
TLS2_k127_191562_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 595.0
TLS2_k127_191562_3 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 568.0
TLS2_k127_191562_4 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005109 275.0
TLS2_k127_191562_5 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.000000000000000000000000000000000000000000000000000000000000000009588 229.0
TLS2_k127_191562_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0005456 53.0
TLS2_k127_1928296_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 349.0
TLS2_k127_1928296_1 nucleotidyltransferase activity - - - 0.000004529 52.0
TLS2_k127_1965545_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 1.417e-222 719.0
TLS2_k127_1965545_1 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 573.0
TLS2_k127_1965545_3 Belongs to the FPP GGPP synthase family - - - 0.000000000000000000000000000000000001807 145.0
TLS2_k127_1965545_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000001356 82.0
TLS2_k127_1969733_0 iron ion homeostasis K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 360.0
TLS2_k127_1969733_1 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000009629 233.0
TLS2_k127_1975172_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 438.0
TLS2_k127_1975172_1 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 295.0
TLS2_k127_1975172_2 Type II secretion system protein B - - - 0.00000002527 58.0
TLS2_k127_1978207_0 - - - - 0.00000000000000000000000000000001499 129.0
TLS2_k127_1978207_1 Domain of unknown function (DUF4926) - - - 0.00000000000000000000000001675 113.0
TLS2_k127_198412_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 3.749e-201 632.0
TLS2_k127_198412_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009784 566.0
TLS2_k127_198412_2 Indoleamine 2,3-dioxygenase K00463 - 1.13.11.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 465.0
TLS2_k127_198412_3 NAD dependent epimerase/dehydratase family K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 456.0
TLS2_k127_198412_4 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 404.0
TLS2_k127_1988077_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 569.0
TLS2_k127_1988077_1 AcrB/AcrD/AcrF family K03296,K18138,K18902 - - 0.0000000000000000000000000000000000009529 141.0
TLS2_k127_200936_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1860.0
TLS2_k127_200936_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 296.0
TLS2_k127_200936_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000001108 243.0
TLS2_k127_2037256_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 3.01e-285 886.0
TLS2_k127_2037256_1 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 571.0
TLS2_k127_2037256_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 325.0
TLS2_k127_2037256_3 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000006774 121.0
TLS2_k127_2037256_4 protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000007645 100.0
TLS2_k127_2042746_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.168e-218 690.0
TLS2_k127_2042746_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 520.0
TLS2_k127_2042746_2 Pfam:AHS2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 385.0
TLS2_k127_2042746_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 356.0
TLS2_k127_2042746_4 LamB/YcsF family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 335.0
TLS2_k127_2042746_5 Pfam:AHS1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002437 279.0
TLS2_k127_2042746_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000001494 235.0
TLS2_k127_2042746_7 FCD - - - 0.0000000000000000000000000000000000000000000000000001104 194.0
TLS2_k127_2042746_8 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000004423 190.0
TLS2_k127_2042746_9 deoxyhypusine monooxygenase activity - - - 0.0000004814 61.0
TLS2_k127_2044334_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000006069 259.0
TLS2_k127_2044334_1 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000005956 192.0
TLS2_k127_2044334_2 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000001352 173.0
TLS2_k127_2047565_0 PFAM Heparinase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 408.0
TLS2_k127_2047565_1 PFAM glycosyl transferase WecB TagA CpsF K05946 - 2.4.1.187 0.0000000006754 64.0
TLS2_k127_2075269_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.977e-215 678.0
TLS2_k127_2075269_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000009588 259.0
TLS2_k127_2075269_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000586 224.0
TLS2_k127_2075269_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000005533 188.0
TLS2_k127_2081459_0 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 353.0
TLS2_k127_2081459_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001134 274.0
TLS2_k127_2081459_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000562 244.0
TLS2_k127_210169_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K07250 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 542.0
TLS2_k127_210169_1 Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate K06447 - 1.2.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 489.0
TLS2_k127_210169_2 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 383.0
TLS2_k127_210169_3 peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000005487 204.0
TLS2_k127_2119753_0 Histidine kinase K10125 - 2.7.13.3 4.992e-197 635.0
TLS2_k127_2119753_1 Bacterial regulatory protein, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 629.0
TLS2_k127_2119753_2 PFAM Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 572.0
TLS2_k127_214350_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600,K00605,K18847 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.1,2.1.2.10,2.2.1.8 0.0 1099.0
TLS2_k127_214350_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 325.0
TLS2_k127_214350_2 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000003633 212.0
TLS2_k127_214350_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000009793 175.0
TLS2_k127_2178805_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.901e-295 914.0
TLS2_k127_2178805_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 354.0
TLS2_k127_2178805_2 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000343 260.0
TLS2_k127_2178805_3 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000000000003271 118.0
TLS2_k127_2178805_4 - - - - 0.00000000000000000000000008007 108.0
TLS2_k127_2178805_5 Methyltransferase domain - - - 0.000004234 51.0
TLS2_k127_2178805_6 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 0.00001219 52.0
TLS2_k127_2206899_0 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 1.219e-261 825.0
TLS2_k127_2206899_1 transport system, permease component K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 568.0
TLS2_k127_2206899_2 transport system, permease component K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 554.0
TLS2_k127_2208980_0 DEAD DEAH box helicase K06877 - - 0.0 1144.0
TLS2_k127_2208980_1 Putative regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000005721 209.0
TLS2_k127_2208980_3 RNase_H superfamily K07502 - - 0.0002561 51.0
TLS2_k127_2237990_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 622.0
TLS2_k127_2237990_1 PFAM Glycosyl transferase family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 546.0
TLS2_k127_2237990_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 368.0
TLS2_k127_2237990_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 328.0
TLS2_k127_2237990_4 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 316.0
TLS2_k127_2237990_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000102 243.0
TLS2_k127_2237990_6 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000001263 218.0
TLS2_k127_2237990_7 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000000009277 190.0
TLS2_k127_2269551_0 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 359.0
TLS2_k127_2269551_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 340.0
TLS2_k127_2269551_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 300.0
TLS2_k127_2269551_3 Mammalian cell entry related domain protein K02067,K06192 - - 0.0000000000000000000000000000000000000000001925 179.0
TLS2_k127_2269551_4 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000001414 101.0
TLS2_k127_2269551_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000001176 78.0
TLS2_k127_2279208_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 2.485e-281 871.0
TLS2_k127_2279208_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 6.804e-229 728.0
TLS2_k127_2279208_10 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 479.0
TLS2_k127_2279208_11 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 439.0
TLS2_k127_2279208_12 Indoleamine 2,3-dioxygenase K00463 - 1.13.11.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 412.0
TLS2_k127_2279208_13 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 399.0
TLS2_k127_2279208_14 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 381.0
TLS2_k127_2279208_15 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 330.0
TLS2_k127_2279208_16 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000008239 224.0
TLS2_k127_2279208_17 Peptidase M16C associated K06972 - - 0.0000000000000000000000000000000000000000000000000000001205 198.0
TLS2_k127_2279208_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 588.0
TLS2_k127_2279208_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 601.0
TLS2_k127_2279208_4 ABC transporter transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 605.0
TLS2_k127_2279208_5 ABC transporter transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 587.0
TLS2_k127_2279208_6 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 573.0
TLS2_k127_2279208_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 539.0
TLS2_k127_2279208_8 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 524.0
TLS2_k127_2279208_9 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 486.0
TLS2_k127_2334533_0 elongation factor SelB, winged helix K03833 - - 3.582e-256 805.0
TLS2_k127_2334533_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 407.0
TLS2_k127_2334533_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 308.0
TLS2_k127_2334533_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000005546 229.0
TLS2_k127_2334533_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000001218 198.0
TLS2_k127_2343419_0 epimerase dehydratase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 344.0
TLS2_k127_2343419_1 coenzyme F420 binding K00275 - 1.4.3.5 0.0000002313 63.0
TLS2_k127_2384646_0 ABC transporter, transmembrane region K06147,K11085 - - 5.458e-247 779.0
TLS2_k127_2440358_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 624.0
TLS2_k127_2440358_1 HRDC domain protein K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 367.0
TLS2_k127_2440358_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000001558 229.0
TLS2_k127_2440358_3 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000139 194.0
TLS2_k127_2440358_4 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000000000000000001073 186.0
TLS2_k127_2440358_5 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000003225 122.0
TLS2_k127_2445575_0 Lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 331.0
TLS2_k127_2445575_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000002256 214.0
TLS2_k127_2445575_2 Sensor histidine kinase, HAMP and PAS domain-containing - - - 0.00000000000000000000000000000000000000000000003555 176.0
TLS2_k127_2448207_0 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 1.301e-203 659.0
TLS2_k127_2448207_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 503.0
TLS2_k127_2448207_2 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 334.0
TLS2_k127_2448207_3 PFAM regulatory protein, ArsR K21903 - - 0.000000000000000000000000000000000000000000000000001443 184.0
TLS2_k127_2448207_4 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000347 178.0
TLS2_k127_2452731_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 366.0
TLS2_k127_2452731_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 332.0
TLS2_k127_2452731_2 PFAM regulatory protein TetR K16137 - - 0.000000000000000000000000000000000000000000000000000001244 201.0
TLS2_k127_2452731_3 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000004104 184.0
TLS2_k127_2452731_4 Protein of unknown function (DUF504) - - - 0.00000000000000000001318 97.0
TLS2_k127_248636_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 409.0
TLS2_k127_248636_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000003516 220.0
TLS2_k127_2552823_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 401.0
TLS2_k127_2552823_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 320.0
TLS2_k127_2552823_2 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002811 248.0
TLS2_k127_2552823_3 phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000001622 157.0
TLS2_k127_2564366_0 aconitate hydratase K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 351.0
TLS2_k127_2564366_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000003785 173.0
TLS2_k127_2564366_2 Protein of unknown function (DUF433) - - - 0.00000000000000000000000009949 110.0
TLS2_k127_2564366_3 - - - - 0.0000000000000000000006037 106.0
TLS2_k127_2564366_4 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000001895 78.0
TLS2_k127_2568531_0 Belongs to the ClpA ClpB family K03694 - - 5.763e-292 919.0
TLS2_k127_2568531_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 383.0
TLS2_k127_2568531_2 PilX N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000002153 220.0
TLS2_k127_2568531_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000004153 120.0
TLS2_k127_2568531_4 type IV pilus modification protein PilV K02459,K02671 - - 0.0000000000000000002608 98.0
TLS2_k127_2582378_0 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 554.0
TLS2_k127_2582378_1 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000004804 222.0
TLS2_k127_2598877_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 384.0
TLS2_k127_2598877_1 transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000001281 210.0
TLS2_k127_2600659_0 unfolded protein binding K04079 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701 - 1.275e-248 789.0
TLS2_k127_2600659_1 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000004508 259.0
TLS2_k127_2634723_0 Belongs to the BCCT transporter (TC 2.A.15) family - - - 7.433e-225 710.0
TLS2_k127_2634723_1 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 425.0
TLS2_k127_2634723_2 Methionine synthase B12-binding module cap domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 323.0
TLS2_k127_2634723_3 Trimethylamine methyltransferase MttB (TMA methyltransferase) K14083 - 2.1.1.250 0.000000000000000000000000000007971 119.0
TLS2_k127_2634723_4 COGs COG0145 N-methylhydantoinase A acetone carboxylase beta subunit - - - 0.0005371 47.0
TLS2_k127_2658607_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 442.0
TLS2_k127_2658607_1 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 369.0
TLS2_k127_2658607_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 330.0
TLS2_k127_2658607_3 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001663 276.0
TLS2_k127_2658607_4 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000003716 248.0
TLS2_k127_2658607_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000001692 159.0
TLS2_k127_2658607_6 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000001821 155.0
TLS2_k127_2672369_0 PFAM Iron permease FTR1 - - - 0.000000000000000000000000000000000000000000000000000003658 201.0
TLS2_k127_2672369_1 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000002751 146.0
TLS2_k127_2695468_0 histidine kinase HAMP region domain protein - - - 0.0 1148.0
TLS2_k127_2695468_1 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 6.592e-263 833.0
TLS2_k127_2695468_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 426.0
TLS2_k127_2695468_3 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 402.0
TLS2_k127_2695468_4 Belongs to the SfsA family K06206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 353.0
TLS2_k127_2695468_5 Universal stress protein family - - - 0.00000000000004508 80.0
TLS2_k127_2701058_0 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 1.331e-196 619.0
TLS2_k127_2701058_1 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000009238 235.0
TLS2_k127_2701058_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000003786 166.0
TLS2_k127_2701058_3 - - - - 0.000000000000000000000000001948 118.0
TLS2_k127_2701058_5 Smr protein MutS2 - - - 0.00003245 53.0
TLS2_k127_2709140_0 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 491.0
TLS2_k127_2709140_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 288.0
TLS2_k127_2726465_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 522.0
TLS2_k127_2726465_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000002662 279.0
TLS2_k127_2728000_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 421.0
TLS2_k127_2728000_1 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000006256 223.0
TLS2_k127_2728000_2 PFAM Glycosyl K12994 - 2.4.1.349 0.0000000000000000000000000000000000007613 159.0
TLS2_k127_2728000_3 Methionine biosynthesis protein MetW - - - 0.000000000000000000004361 108.0
TLS2_k127_2728000_4 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000001135 56.0
TLS2_k127_2731314_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 4.092e-208 655.0
TLS2_k127_2731314_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 498.0
TLS2_k127_2731314_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 421.0
TLS2_k127_2731314_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 293.0
TLS2_k127_2731314_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005928 289.0
TLS2_k127_2731314_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000001967 177.0
TLS2_k127_2737983_0 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 531.0
TLS2_k127_2737983_1 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 509.0
TLS2_k127_2737983_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 366.0
TLS2_k127_2737983_3 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001572 263.0
TLS2_k127_2737983_4 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002592 234.0
TLS2_k127_2765700_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 363.0
TLS2_k127_2765700_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001124 270.0
TLS2_k127_2779232_0 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 516.0
TLS2_k127_2779232_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 376.0
TLS2_k127_2779232_2 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005278 271.0
TLS2_k127_2779232_3 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000003678 179.0
TLS2_k127_2779232_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000003033 145.0
TLS2_k127_2779232_5 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000001973 141.0
TLS2_k127_2779232_6 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000329 135.0
TLS2_k127_2783668_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000009741 70.0
TLS2_k127_2783668_1 protein transport across the cell outer membrane K02246,K10926 - - 0.0000004123 63.0
TLS2_k127_2783668_2 type IV pilus modification protein PilV K02458,K02671 - - 0.00004593 55.0
TLS2_k127_2783741_1 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 445.0
TLS2_k127_2783741_2 pfam abc1 K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 423.0
TLS2_k127_2783741_3 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000000000000000000000000000000000003132 203.0
TLS2_k127_2783741_4 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000003224 168.0
TLS2_k127_2795280_0 Proton-conducting membrane transporter - - - 1.932e-227 717.0
TLS2_k127_2795280_1 PFAM NADH Ubiquinone plastoquinone (complex I) K05568,K12137 - - 2.038e-221 703.0
TLS2_k127_2795280_10 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.000000000000000000000000001496 119.0
TLS2_k127_2795280_11 Multiple resistance and pH regulation protein F (MrpF / PhaF) - - - 0.0000000000000000000000002227 117.0
TLS2_k127_2795280_12 Protein conserved in bacteria - - - 0.00000000000000000000000491 104.0
TLS2_k127_2795280_13 Domain of unknown function (DUF4040) - - - 0.00000000000000000001524 99.0
TLS2_k127_2795280_14 TIGRFAM YgiT-type zinc finger domain - - - 0.00000000003237 64.0
TLS2_k127_2795280_15 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.00000002829 66.0
TLS2_k127_2795280_17 Lipocalin-like domain - - - 0.0006633 48.0
TLS2_k127_2795280_2 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 5.034e-206 657.0
TLS2_k127_2795280_3 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 309.0
TLS2_k127_2795280_4 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 291.0
TLS2_k127_2795280_5 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000000000000000000009597 203.0
TLS2_k127_2795280_6 Domain related to MnhB subunit of Na+/H+ antiporter - - - 0.0000000000000000000000000000000000000000000000009742 183.0
TLS2_k127_2795280_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L - - - 0.000000000000000000000000000000006082 131.0
TLS2_k127_2795280_8 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05564,K05571 - - 0.00000000000000000000000000003689 126.0
TLS2_k127_2795280_9 Na H antiporter - - - 0.0000000000000000000000000002006 123.0
TLS2_k127_2807127_0 RQC K03654 - 3.6.4.12 4.374e-257 814.0
TLS2_k127_2807127_1 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000005206 207.0
TLS2_k127_2807127_2 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.0000000000000000000000000000000000000000000000000000002018 201.0
TLS2_k127_2811694_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 316.0
TLS2_k127_2811694_1 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 312.0
TLS2_k127_2811694_2 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000506 253.0
TLS2_k127_2811694_3 TAP-like protein K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000001816 239.0
TLS2_k127_2811694_4 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000001507 163.0
TLS2_k127_2813578_0 Glyoxalase-like domain K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001561 240.0
TLS2_k127_2813578_1 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000001062 240.0
TLS2_k127_2813578_2 Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000000000000000000000000006494 198.0
TLS2_k127_2813578_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000008807 61.0
TLS2_k127_2813578_4 glyoxalase III activity K02005 - - 0.0000001056 61.0
TLS2_k127_2820216_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 9.142e-195 613.0
TLS2_k127_2820216_1 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 565.0
TLS2_k127_2820216_2 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 471.0
TLS2_k127_2820216_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 381.0
TLS2_k127_2820216_5 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 319.0
TLS2_k127_2820216_6 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000032 268.0
TLS2_k127_2820216_7 - - - - 0.000000000000000000000000000000000000000000000000127 188.0
TLS2_k127_2823797_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 5e-324 1005.0
TLS2_k127_2823797_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 476.0
TLS2_k127_2823797_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 382.0
TLS2_k127_2823797_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 312.0
TLS2_k127_2823797_4 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 295.0
TLS2_k127_2823797_5 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001027 244.0
TLS2_k127_2823797_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000004507 233.0
TLS2_k127_2823797_7 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000000000000000000000000000000007551 209.0
TLS2_k127_2834106_0 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 3.266e-309 953.0
TLS2_k127_2834106_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.834e-200 647.0
TLS2_k127_2834106_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 566.0
TLS2_k127_2834106_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 503.0
TLS2_k127_2834106_4 2Fe-2S iron-sulfur cluster binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 456.0
TLS2_k127_2834106_5 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 279.0
TLS2_k127_2834106_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000392 254.0
TLS2_k127_2834937_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 1.856e-223 711.0
TLS2_k127_2834937_1 CoA-transferase family III - - - 1.322e-200 630.0
TLS2_k127_2834937_2 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 462.0
TLS2_k127_2834937_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 283.0
TLS2_k127_2834937_4 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002145 282.0
TLS2_k127_2834937_5 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000345 172.0
TLS2_k127_2834937_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000003554 143.0
TLS2_k127_2855387_0 - - - - 1.834e-275 878.0
TLS2_k127_2855387_1 Subtilase family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 453.0
TLS2_k127_2855387_2 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000002402 236.0
TLS2_k127_2855387_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000001174 220.0
TLS2_k127_2855387_5 Glyco_18 K01183 - 3.2.1.14 0.0000004941 63.0
TLS2_k127_2864903_0 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001047 225.0
TLS2_k127_2868943_0 Sigma-54 interaction domain K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 524.0
TLS2_k127_2868943_1 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 412.0
TLS2_k127_2868943_10 helix_turn_helix, Lux Regulon - - - 0.00000000000000000008504 102.0
TLS2_k127_2868943_11 PFAM Outer membrane efflux protein - - - 0.0000000939 64.0
TLS2_k127_2868943_2 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 307.0
TLS2_k127_2868943_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 307.0
TLS2_k127_2868943_4 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007038 276.0
TLS2_k127_2868943_5 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000005976 254.0
TLS2_k127_2868943_6 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000001228 213.0
TLS2_k127_2868943_7 Transketolase, pyrimidine binding domain K00167,K21417 - 1.2.4.4 0.00000000000000000000000000000000000003278 158.0
TLS2_k127_2868943_8 histidine kinase A domain protein - - - 0.000000000000000000000000000007377 138.0
TLS2_k127_2868943_9 Protein of unknown function (DUF2860) - - - 0.0000000000000000000004258 111.0
TLS2_k127_2873423_0 His Kinase A (phosphoacceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 477.0
TLS2_k127_2873423_1 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000005838 229.0
TLS2_k127_2902969_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 3.995e-274 858.0
TLS2_k127_2902969_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 595.0
TLS2_k127_2902969_10 PTS system sorbose-specific iic component K02795 - - 0.0000000000000001673 94.0
TLS2_k127_2902969_2 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 458.0
TLS2_k127_2902969_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 428.0
TLS2_k127_2902969_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003917 256.0
TLS2_k127_2902969_5 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000003622 239.0
TLS2_k127_2902969_6 system, mannose fructose sorbose family, IID component K02796 - - 0.00000000000000000000000000000000000000000000000015 195.0
TLS2_k127_2902969_7 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.000000000000000000000000000000000000000000001527 168.0
TLS2_k127_2902969_8 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000000000000000000003561 148.0
TLS2_k127_2902969_9 TIGRFAM phosphocarrier, HPr family K11189 - - 0.00000000000000000000000001322 125.0
TLS2_k127_2909780_0 Histidine kinase K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 428.0
TLS2_k127_2909780_1 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000003761 213.0
TLS2_k127_2909780_2 Histidine kinase - - - 0.00000000000002294 73.0
TLS2_k127_2947225_0 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 3.053e-317 992.0
TLS2_k127_2947225_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 9.419e-233 728.0
TLS2_k127_2947225_2 PBS lyase HEAT-like repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 444.0
TLS2_k127_2947225_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 406.0
TLS2_k127_2947225_4 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 301.0
TLS2_k127_2947225_5 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006367 259.0
TLS2_k127_2947225_6 competence protein K02242 - - 0.0000000000000000000000000000000000000000000000000000000000000001412 242.0
TLS2_k127_296807_0 Cache domain - - - 2.965e-249 783.0
TLS2_k127_296807_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 425.0
TLS2_k127_296807_2 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 301.0
TLS2_k127_296807_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000006207 136.0
TLS2_k127_297274_0 penicillin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 538.0
TLS2_k127_297274_1 PFAM peptidase M20 K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 463.0
TLS2_k127_297274_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 336.0
TLS2_k127_297274_3 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 335.0
TLS2_k127_297274_4 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003384 235.0
TLS2_k127_297274_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000002111 233.0
TLS2_k127_297274_7 CheY-like receiver, AAA-type ATPase and DNA-binding domain-containing response regulator - - - 0.00000000000000000000000000000000000008469 157.0
TLS2_k127_297274_8 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000001652 151.0
TLS2_k127_297274_9 - - - - 0.00000000000000000000000000000000007694 147.0
TLS2_k127_2986109_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 494.0
TLS2_k127_2986109_1 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000005493 239.0
TLS2_k127_2986109_2 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000000000000000000000002639 213.0
TLS2_k127_2986109_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000002382 209.0
TLS2_k127_2986109_4 TIGRFAM phosphodiesterase, MJ0936 family K07095 - - 0.00000000000000000000000000000000000000000000000000000003134 206.0
TLS2_k127_3009634_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000004794 262.0
TLS2_k127_3009634_1 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.00000000000000000000000000000000000000000008811 162.0
TLS2_k127_3009634_2 Protein of unknown function DUF134 - - - 0.000000000000000000000000005333 116.0
TLS2_k127_3009634_3 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000006577 57.0
TLS2_k127_3012957_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 417.0
TLS2_k127_3012957_1 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 373.0
TLS2_k127_3012957_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000004426 177.0
TLS2_k127_3012957_3 GTP-binding protein - - - 0.00000000000000000000000000000000008748 153.0
TLS2_k127_3025101_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1188.0
TLS2_k127_3025101_1 TIGRFAM 2-oxoglutarate dehydrogenase, E1 subunit K00164 - 1.2.4.2 3.775e-305 961.0
TLS2_k127_3025101_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 569.0
TLS2_k127_3025101_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 455.0
TLS2_k127_3025869_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.373e-252 788.0
TLS2_k127_3025869_1 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 373.0
TLS2_k127_3098096_0 SMART Nucleotide binding protein, PINc K07175 - - 4.894e-235 732.0
TLS2_k127_3098096_1 PFAM aminotransferase class I and II - - - 1.638e-194 613.0
TLS2_k127_3098096_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 506.0
TLS2_k127_3098096_3 PFAM aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 507.0
TLS2_k127_3098096_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007345 290.0
TLS2_k127_3098096_5 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000000000000001334 177.0
TLS2_k127_3132533_0 PFAM Silent information regulator protein Sir2 K12410 - - 0.0000000000000000000000000000000000000000000000000000000001655 205.0
TLS2_k127_3132533_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000008911 188.0
TLS2_k127_3132533_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000001566 88.0
TLS2_k127_3132884_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 439.0
TLS2_k127_3132884_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 364.0
TLS2_k127_3132884_2 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004358 276.0
TLS2_k127_3132884_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000001133 223.0
TLS2_k127_3132884_4 DsbA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000002732 184.0
TLS2_k127_3132884_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000004309 154.0
TLS2_k127_3132884_6 CAAX protease self-immunity - - - 0.00000000008089 74.0
TLS2_k127_3132884_7 SpoIIAA-like - - - 0.0000001368 61.0
TLS2_k127_3144188_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 390.0
TLS2_k127_3144188_1 Glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 334.0
TLS2_k127_3144188_2 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 323.0
TLS2_k127_3144188_3 transport system periplasmic component - - - 0.0000000000000000000000000000004975 132.0
TLS2_k127_3188012_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1528.0
TLS2_k127_319251_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1262.0
TLS2_k127_319251_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 317.0
TLS2_k127_319251_2 SMART helicase c2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000007032 256.0
TLS2_k127_319251_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000195 165.0
TLS2_k127_3237591_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 519.0
TLS2_k127_3237591_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 360.0
TLS2_k127_3237591_2 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 346.0
TLS2_k127_3237591_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005293 270.0
TLS2_k127_3237591_4 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000000000000000000000000000000000000000000004141 221.0
TLS2_k127_3237591_5 Heavy-metal-associated domain - - - 0.00000000000001171 84.0
TLS2_k127_3284846_0 Histidine kinase A domain protein - - - 0.0 1506.0
TLS2_k127_3284846_1 EXOIII K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 520.0
TLS2_k127_3284846_2 DnaJ central domain K03686 - - 0.0000000000000000000000000000002052 125.0
TLS2_k127_3284846_3 - - - - 0.000000000001081 73.0
TLS2_k127_3303673_0 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 8.23e-219 683.0
TLS2_k127_3303673_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 310.0
TLS2_k127_3303673_2 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000007587 125.0
TLS2_k127_3375530_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 318.0
TLS2_k127_3375530_1 Pseudouridine synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 302.0
TLS2_k127_3375530_2 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007613 254.0
TLS2_k127_3423717_0 Glycosyl transferase, family 2 - - - 0.000003791 59.0
TLS2_k127_3423717_1 Uncharacterised nucleotidyltransferase - - - 0.00008123 52.0
TLS2_k127_3453230_0 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 431.0
TLS2_k127_3453230_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 372.0
TLS2_k127_3453230_2 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 350.0
TLS2_k127_3453230_3 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 340.0
TLS2_k127_3453230_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000132 278.0
TLS2_k127_3453230_5 Nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000001732 174.0
TLS2_k127_3478397_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.014e-211 670.0
TLS2_k127_3478397_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 310.0
TLS2_k127_348914_0 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 574.0
TLS2_k127_348914_1 diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000001884 98.0
TLS2_k127_348914_2 cytochrome K00412 - - 0.000000000000001744 89.0
TLS2_k127_348914_3 - - - - 0.000001484 61.0
TLS2_k127_3507530_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K11392 - 2.1.1.178 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 389.0
TLS2_k127_3507530_1 Calcineurin-like phosphoesterase K07099 - - 0.00000000000000000000000000000000000000000000000000000000000000000008427 241.0
TLS2_k127_3507530_2 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000009087 199.0
TLS2_k127_3507530_3 Pfam:Nol1_Nop2_Fmu_2 - - - 0.000154 50.0
TLS2_k127_3544275_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 4.06e-229 716.0
TLS2_k127_3544275_1 Flavodoxin - - - 7.725e-198 624.0
TLS2_k127_3544275_10 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000008539 191.0
TLS2_k127_3544275_11 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000002252 173.0
TLS2_k127_3544275_12 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000003823 86.0
TLS2_k127_3544275_13 PFAM NADPH-dependent FMN reductase - - - 0.000000000000001522 79.0
TLS2_k127_3544275_15 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.00000005701 63.0
TLS2_k127_3544275_16 Rubrerythrin - - - 0.0000003711 57.0
TLS2_k127_3544275_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 575.0
TLS2_k127_3544275_3 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 378.0
TLS2_k127_3544275_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 377.0
TLS2_k127_3544275_5 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 324.0
TLS2_k127_3544275_6 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003648 287.0
TLS2_k127_3544275_7 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.000000000000000000000000000000000000000000000000000000000000006236 218.0
TLS2_k127_3544275_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000002352 219.0
TLS2_k127_3544275_9 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000003231 221.0
TLS2_k127_3565692_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1343.0
TLS2_k127_3565692_1 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 301.0
TLS2_k127_3565692_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000000000000000000000000000000000000000000000000000000002886 221.0
TLS2_k127_3565692_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000003774 207.0
TLS2_k127_3565692_4 - - - - 0.00004129 50.0
TLS2_k127_3604683_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 432.0
TLS2_k127_3604683_1 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000000005865 154.0
TLS2_k127_3604683_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000005429 162.0
TLS2_k127_3604683_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000001751 134.0
TLS2_k127_3604683_4 Transcriptional regulator - - - 0.0000000000000000000000000000009252 134.0
TLS2_k127_3604683_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000001632 127.0
TLS2_k127_3604683_6 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000007424 117.0
TLS2_k127_3604683_7 Metallo-beta-lactamase superfamily - - - 0.0003061 43.0
TLS2_k127_3625445_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1092.0
TLS2_k127_3625445_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 5.193e-251 787.0
TLS2_k127_3625445_10 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000000004707 117.0
TLS2_k127_3625445_2 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 579.0
TLS2_k127_3625445_3 peptidase M48, Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 572.0
TLS2_k127_3625445_4 PFAM Magnesium chelatase, subunit ChlI K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 551.0
TLS2_k127_3625445_5 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 443.0
TLS2_k127_3625445_6 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 402.0
TLS2_k127_3625445_7 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 317.0
TLS2_k127_3625445_8 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003191 289.0
TLS2_k127_3625445_9 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000004574 248.0
TLS2_k127_3626319_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1535.0
TLS2_k127_3626319_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.149e-229 716.0
TLS2_k127_3626319_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 440.0
TLS2_k127_3626319_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 355.0
TLS2_k127_3626319_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 353.0
TLS2_k127_3626319_5 DsrE/DsrF-like family - - - 0.0004736 51.0
TLS2_k127_3638872_0 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000901 190.0
TLS2_k127_3638872_1 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000174 142.0
TLS2_k127_3638872_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000005776 96.0
TLS2_k127_3638872_3 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000002506 98.0
TLS2_k127_3640521_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 543.0
TLS2_k127_3640521_1 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 383.0
TLS2_k127_3640521_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000003815 92.0
TLS2_k127_364511_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 576.0
TLS2_k127_364511_1 Flavodoxin-like fold K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 321.0
TLS2_k127_364511_2 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000004095 146.0
TLS2_k127_365040_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179,K04090 - 1.2.7.8 2.892e-298 945.0
TLS2_k127_365040_1 PFAM Cation transporter K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 342.0
TLS2_k127_365040_2 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002382 280.0
TLS2_k127_365040_3 Indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000671 265.0
TLS2_k127_365040_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000005098 60.0
TLS2_k127_3699397_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 619.0
TLS2_k127_3699397_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 441.0
TLS2_k127_3699397_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000127 204.0
TLS2_k127_3699397_3 - - - - 0.00000000000000000000000000000000000000000000000000001263 199.0
TLS2_k127_3699397_4 Rubrerythrin - - - 0.000000000004215 73.0
TLS2_k127_3712963_0 DAHP synthetase I family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 620.0
TLS2_k127_3712963_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 569.0
TLS2_k127_3712963_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 492.0
TLS2_k127_3712963_3 CBS domain containing protein K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 340.0
TLS2_k127_3712963_4 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000000000000000000001259 153.0
TLS2_k127_3712963_5 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I K01840 - 5.4.2.8 0.00000000000002106 78.0
TLS2_k127_3732616_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 537.0
TLS2_k127_3732616_1 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000002265 178.0
TLS2_k127_3732616_2 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000001788 176.0
TLS2_k127_3732616_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000009549 170.0
TLS2_k127_3732616_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000008742 141.0
TLS2_k127_373716_0 flagellar motor switch protein FliM K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 475.0
TLS2_k127_373716_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 456.0
TLS2_k127_373716_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 382.0
TLS2_k127_373716_3 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 358.0
TLS2_k127_373716_4 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006939 263.0
TLS2_k127_373716_5 PFAM Transcription factor CarD K07736 - - 0.000000000000000000000000000000000000000000000000000000000000000000008128 241.0
TLS2_k127_3743508_0 AMP-binding enzyme K00666 - - 1.131e-245 776.0
TLS2_k127_3743508_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 5.771e-199 625.0
TLS2_k127_3743508_10 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000007458 59.0
TLS2_k127_3743508_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 601.0
TLS2_k127_3743508_3 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 492.0
TLS2_k127_3743508_4 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 477.0
TLS2_k127_3743508_5 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000004325 258.0
TLS2_k127_3743508_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000006297 238.0
TLS2_k127_3743508_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000001297 227.0
TLS2_k127_3743508_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000844 230.0
TLS2_k127_3743508_9 Universal stress protein - - - 0.00000000000002291 87.0
TLS2_k127_3775072_0 elongation factor G domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 590.0
TLS2_k127_3775072_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 387.0
TLS2_k127_3775072_2 COG1654 Biotin operon repressor K03524 - 6.3.4.15 0.00008661 46.0
TLS2_k127_3777394_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.703e-226 721.0
TLS2_k127_3777394_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 404.0
TLS2_k127_3777394_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 356.0
TLS2_k127_3777394_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 331.0
TLS2_k127_3777394_4 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 304.0
TLS2_k127_3777394_5 Nucleotide-binding protein implicated in inhibition of septum formation K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000492 223.0
TLS2_k127_3777394_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000003628 139.0
TLS2_k127_3814641_0 Bile acid sodium symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 377.0
TLS2_k127_3814641_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006836 265.0
TLS2_k127_3814641_2 Protein of unknown function (DUF3141) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008171 248.0
TLS2_k127_3814641_3 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000001569 257.0
TLS2_k127_3814641_4 Iron-storage protein - - - 0.00000000000000000000000000000000000000000000000000000000000007599 221.0
TLS2_k127_3814641_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000001279 89.0
TLS2_k127_3842926_0 PFAM magnesium chelatase ChlI subunit K07391 - - 6.582e-236 739.0
TLS2_k127_3842926_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 335.0
TLS2_k127_3842926_2 Nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000001757 154.0
TLS2_k127_3845403_0 ATP-binding region ATPase domain protein - - - 1.274e-228 735.0
TLS2_k127_3845403_1 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 351.0
TLS2_k127_3845403_2 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 308.0
TLS2_k127_3845403_3 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000001166 220.0
TLS2_k127_3845403_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000005983 213.0
TLS2_k127_3845403_5 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000001355 155.0
TLS2_k127_3863272_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 1.271e-226 714.0
TLS2_k127_3863272_1 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 501.0
TLS2_k127_3863272_2 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 419.0
TLS2_k127_3863272_3 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 391.0
TLS2_k127_3863272_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001358 249.0
TLS2_k127_3901407_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 494.0
TLS2_k127_3901407_1 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 422.0
TLS2_k127_3901407_2 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000002013 213.0
TLS2_k127_3926703_0 Belongs to the GARS family K01945 - 6.3.4.13 8.181e-213 668.0
TLS2_k127_3926703_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 526.0
TLS2_k127_3926703_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000001171 78.0
TLS2_k127_3926703_11 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000002398 81.0
TLS2_k127_3926703_12 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000001354 61.0
TLS2_k127_3926703_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 531.0
TLS2_k127_3926703_3 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 319.0
TLS2_k127_3926703_4 PFAM MGS domain protein K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 303.0
TLS2_k127_3926703_5 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000437 291.0
TLS2_k127_3926703_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000001005 145.0
TLS2_k127_3926703_7 Endoribonuclease L-PSP - - - 0.000000000000000000000000005485 115.0
TLS2_k127_3926703_8 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000001237 81.0
TLS2_k127_3926703_9 PFAM cytochrome c class III - - - 0.00000000000006696 77.0
TLS2_k127_3927534_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 539.0
TLS2_k127_3927534_1 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 467.0
TLS2_k127_3927534_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 344.0
TLS2_k127_3927534_3 P2 response regulator binding domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 334.0
TLS2_k127_3927534_4 PASTA K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 308.0
TLS2_k127_3927534_6 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000004951 167.0
TLS2_k127_3927534_7 Major facilitator Superfamily - - - 0.0000000000000000000000007347 115.0
TLS2_k127_3932519_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 1.529e-258 809.0
TLS2_k127_3932519_1 extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 453.0
TLS2_k127_3932519_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 451.0
TLS2_k127_3932519_3 cyclopropane-fatty-acyl-phospholipid synthase - - - 0.0000000000000000000000000000000000000000001262 167.0
TLS2_k127_3932519_4 Helix-turn-helix domain, rpiR family - - - 0.00000000000000000000000728 104.0
TLS2_k127_3997480_0 pilus assembly protein PilW K01342,K02672,K20276 - 3.4.21.62 1.749e-258 840.0
TLS2_k127_3997480_1 PilX N-terminal - - - 0.00000002267 61.0
TLS2_k127_3998064_0 PFAM Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 353.0
TLS2_k127_3998064_1 [2Fe-2S] binding domain K07302,K18029 - 1.17.2.1,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000009194 225.0
TLS2_k127_3998064_2 Aldehyde oxidase and xanthine dehydrogenase K00256 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000002943 229.0
TLS2_k127_3998064_3 DGC domain - - - 0.000000000000000000000000002254 118.0
TLS2_k127_4023417_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0 1103.0
TLS2_k127_4023417_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 514.0
TLS2_k127_4023417_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002219 259.0
TLS2_k127_4023417_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000001005 232.0
TLS2_k127_4023417_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000001505 109.0
TLS2_k127_4031879_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 2.264e-212 683.0
TLS2_k127_4031879_1 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 588.0
TLS2_k127_4031879_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000001115 260.0
TLS2_k127_4031879_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000001562 230.0
TLS2_k127_4031879_4 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000000000000000000000004644 208.0
TLS2_k127_4031879_5 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000009954 106.0
TLS2_k127_4038339_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 492.0
TLS2_k127_4038339_1 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000006985 253.0
TLS2_k127_4038339_2 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000001431 221.0
TLS2_k127_4038339_3 ferrous iron transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000002408 187.0
TLS2_k127_4038339_4 ferrous iron transmembrane transporter activity - - - 0.00000000000000000000000000000000001032 145.0
TLS2_k127_4043337_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 1.002e-204 648.0
TLS2_k127_4043337_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 492.0
TLS2_k127_404534_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 607.0
TLS2_k127_404534_1 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 350.0
TLS2_k127_404534_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001713 267.0
TLS2_k127_404534_3 17 kDa outer membrane surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000006644 224.0
TLS2_k127_404534_4 Rubrerythrin - - - 0.000000000000000000000000000000000000000000006425 179.0
TLS2_k127_404691_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1361.0
TLS2_k127_404691_1 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 452.0
TLS2_k127_4059393_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 486.0
TLS2_k127_4059393_1 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 453.0
TLS2_k127_4059393_2 HAD-superfamily hydrolase, subfamily IIB K07026 - 3.1.3.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 320.0
TLS2_k127_4059393_3 PFAM Bacterial Ig-like domain (group 2) - - - 0.000001416 52.0
TLS2_k127_4061609_0 HD domain - - - 1.247e-255 801.0
TLS2_k127_4072920_0 PD-(D/E)XK nuclease superfamily K07465 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002366 279.0
TLS2_k127_4077330_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 3.546e-244 762.0
TLS2_k127_4077330_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 3.845e-229 713.0
TLS2_k127_4077330_2 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 5.825e-195 614.0
TLS2_k127_4077330_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 495.0
TLS2_k127_4077330_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 436.0
TLS2_k127_4092093_0 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 316.0
TLS2_k127_4092093_1 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006903 288.0
TLS2_k127_4108266_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006821 255.0
TLS2_k127_4109295_0 PFAM peptidase M1, membrane alanine aminopeptidase - - - 2.394e-299 965.0
TLS2_k127_4109295_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 514.0
TLS2_k127_4109295_2 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000000000004637 227.0
TLS2_k127_411210_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 501.0
TLS2_k127_411210_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 482.0
TLS2_k127_411210_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 439.0
TLS2_k127_411210_3 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 425.0
TLS2_k127_411210_4 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 394.0
TLS2_k127_411210_5 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 304.0
TLS2_k127_411210_6 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 297.0
TLS2_k127_411210_7 PFAM ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000002014 252.0
TLS2_k127_4113012_0 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 418.0
TLS2_k127_4113012_1 ABC-type branched-chain amino acid transport K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 396.0
TLS2_k127_4134514_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain - - - 5.773e-290 899.0
TLS2_k127_4134514_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.338e-208 666.0
TLS2_k127_4134514_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 541.0
TLS2_k127_4134514_3 Flagellar Assembly Protein A K09749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 466.0
TLS2_k127_4134514_4 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 417.0
TLS2_k127_4134514_5 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000177 175.0
TLS2_k127_4134514_6 - - - - 0.000000000000001277 81.0
TLS2_k127_4168243_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 531.0
TLS2_k127_4168243_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 497.0
TLS2_k127_4168243_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 481.0
TLS2_k127_4168243_3 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 389.0
TLS2_k127_4168243_4 Zinc metalloprotease (Elastase) K09607 - - 0.0000004349 63.0
TLS2_k127_4196379_0 Participates in both transcription termination and antitermination K02600 - - 4.816e-212 668.0
TLS2_k127_4196379_1 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 447.0
TLS2_k127_4196379_2 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000736 272.0
TLS2_k127_4196379_3 PFAM Cation transporter K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000332 265.0
TLS2_k127_4196379_4 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006644 260.0
TLS2_k127_4196379_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000003538 179.0
TLS2_k127_4196379_6 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000003763 69.0
TLS2_k127_4207833_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 519.0
TLS2_k127_4207833_1 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000001064 163.0
TLS2_k127_4207833_2 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000002578 99.0
TLS2_k127_4207833_3 Helix-hairpin-helix domain K04477 - - 0.000000007852 57.0
TLS2_k127_4209412_0 - - - - 1.461e-282 885.0
TLS2_k127_4209412_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 447.0
TLS2_k127_4209412_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 408.0
TLS2_k127_4209412_3 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 307.0
TLS2_k127_4209412_4 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000007713 206.0
TLS2_k127_4209412_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000001163 213.0
TLS2_k127_4209412_6 Tetratricopeptide repeat - - - 0.000000000000000000456 100.0
TLS2_k127_4210046_0 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 350.0
TLS2_k127_4210046_1 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002641 263.0
TLS2_k127_4271439_0 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001649 247.0
TLS2_k127_4271439_1 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000001953 247.0
TLS2_k127_4271439_2 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000003669 245.0
TLS2_k127_4271439_3 Bacterial regulatory proteins, tetR family - - - 0.00000008391 59.0
TLS2_k127_4284196_0 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001537 243.0
TLS2_k127_4284196_1 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000000000000000000000009023 195.0
TLS2_k127_4284196_2 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000009049 126.0
TLS2_k127_4291769_0 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 396.0
TLS2_k127_4291769_2 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 327.0
TLS2_k127_4295156_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 356.0
TLS2_k127_4295156_1 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 323.0
TLS2_k127_4295156_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002966 278.0
TLS2_k127_4295156_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000005734 221.0
TLS2_k127_4307548_0 Aminotransferase class I and II K00814 - 2.6.1.2 7.473e-227 713.0
TLS2_k127_4307548_1 phosphomannomutase K01840 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 549.0
TLS2_k127_4307548_2 ATP-dependent DNA helicase K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000004436 49.0
TLS2_k127_4350928_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 478.0
TLS2_k127_4350928_1 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 367.0
TLS2_k127_4350928_2 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003815 255.0
TLS2_k127_4366899_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 2.456e-243 759.0
TLS2_k127_4366899_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.004e-234 734.0
TLS2_k127_4366899_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.682e-207 653.0
TLS2_k127_4366899_3 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 311.0
TLS2_k127_4366899_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000258 208.0
TLS2_k127_4366899_5 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000002771 154.0
TLS2_k127_4366899_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000002375 110.0
TLS2_k127_4366899_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000002342 70.0
TLS2_k127_439443_0 Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 356.0
TLS2_k127_439443_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000008579 251.0
TLS2_k127_439443_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000003228 196.0
TLS2_k127_439443_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000001613 145.0
TLS2_k127_4417382_0 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 1.231e-303 963.0
TLS2_k127_4437751_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 360.0
TLS2_k127_4437751_1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K03796 - - 0.0000000000000000000000000000000000000000000000000000000000004804 224.0
TLS2_k127_4437751_2 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000000000000000000000000000000000002274 178.0
TLS2_k127_445559_0 methylmalonate-semialdehyde dehydrogenase - - - 1.179e-269 836.0
TLS2_k127_445559_1 Amino acid synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 314.0
TLS2_k127_445559_2 ApbE family K09740 - - 0.00000000000000000000000000001947 121.0
TLS2_k127_445559_3 EamA-like transporter family - - - 0.000000000000000000000001678 107.0
TLS2_k127_4474823_0 Belongs to the citrate synthase family K01647 GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350 2.3.3.1 1.105e-208 657.0
TLS2_k127_4474823_1 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 535.0
TLS2_k127_4474823_2 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 479.0
TLS2_k127_4474823_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 438.0
TLS2_k127_4474823_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 435.0
TLS2_k127_4474823_5 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 398.0
TLS2_k127_4474823_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 332.0
TLS2_k127_4474823_7 PFAM response regulator receiver K07659,K11329 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 327.0
TLS2_k127_4489539_0 Domain of unknown function (DUF4070) - - - 9.835e-218 685.0
TLS2_k127_4489539_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 2.143e-199 631.0
TLS2_k127_4489539_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 389.0
TLS2_k127_4489539_3 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002875 270.0
TLS2_k127_4489539_4 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000000000000000004195 215.0
TLS2_k127_4489539_5 - - - - 0.00000000000000000000000001879 113.0
TLS2_k127_4489539_6 - - - - 0.00002631 56.0
TLS2_k127_4498039_0 PFAM ABC transporter related - - - 3.335e-267 832.0
TLS2_k127_4498039_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000005655 129.0
TLS2_k127_4500791_0 Catalyzes the insertion of Co(2 ) into sirohydrochlorin K02190 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0016829,GO:0016852,GO:0020037,GO:0022607,GO:0042597,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050897,GO:0051259,GO:0051262,GO:0051266,GO:0065003,GO:0071840,GO:0097159,GO:1901363 4.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 375.0
TLS2_k127_4500791_1 HAF family - - - 0.000000000000000000000000000000000000000001164 167.0
TLS2_k127_4527672_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 349.0
TLS2_k127_4527672_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000002378 196.0
TLS2_k127_4535026_0 radical SAM domain protein - - - 3.205e-224 705.0
TLS2_k127_4535026_1 radical SAM domain protein - - - 6.488e-222 695.0
TLS2_k127_4535026_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002467 282.0
TLS2_k127_4535026_3 - - - - 0.0000000000000000000000000000000000000000002696 182.0
TLS2_k127_4535950_0 chondroitin AC lyase activity K00694,K01210,K03292 - 2.4.1.12,3.2.1.58 0.0 1050.0
TLS2_k127_4535950_1 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 1.763e-306 945.0
TLS2_k127_4535950_2 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000002378 197.0
TLS2_k127_4535950_3 TRANSCRIPTIONal - - - 0.0000000000000000000000000000001768 123.0
TLS2_k127_4535950_4 SMART Water Stress and Hypersensitive response - - - 0.00000000000000000000000006252 117.0
TLS2_k127_4535950_5 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000002679 71.0
TLS2_k127_4535950_6 - - - - 0.0000001917 56.0
TLS2_k127_4538602_0 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 589.0
TLS2_k127_4538602_1 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 408.0
TLS2_k127_4540030_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.261e-309 959.0
TLS2_k127_4540030_1 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 581.0
TLS2_k127_4540030_10 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000000000000000000000000004665 136.0
TLS2_k127_4540030_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 556.0
TLS2_k127_4540030_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 430.0
TLS2_k127_4540030_4 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 360.0
TLS2_k127_4540030_5 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000009902 255.0
TLS2_k127_4540030_6 Sporulation and spore germination - - - 0.0000000000000000000000000000000000000000000000007306 184.0
TLS2_k127_4540030_7 PFAM periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000001631 187.0
TLS2_k127_4540030_8 protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000002536 171.0
TLS2_k127_4540030_9 EVE domain - - - 0.00000000000000000000000000000000000003875 148.0
TLS2_k127_4544660_0 antibiotic catabolic process K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 479.0
TLS2_k127_4544660_1 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 454.0
TLS2_k127_4544660_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000122 188.0
TLS2_k127_4564253_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 314.0
TLS2_k127_4564253_1 PFAM MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008529 237.0
TLS2_k127_4564253_2 molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000000000000000000000008236 242.0
TLS2_k127_4606659_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 404.0
TLS2_k127_4606659_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 379.0
TLS2_k127_4606659_2 two component, sigma54 specific, transcriptional regulator, Fis family K07714,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000129 223.0
TLS2_k127_4606659_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000000000001344 111.0
TLS2_k127_4613323_0 PFAM Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 620.0
TLS2_k127_4613323_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003887 284.0
TLS2_k127_4613323_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000476 271.0
TLS2_k127_4613323_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000001704 151.0
TLS2_k127_4613323_4 Sporulation and spore germination - - - 0.00000003288 63.0
TLS2_k127_4621042_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.848e-232 727.0
TLS2_k127_4621042_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003121 271.0
TLS2_k127_4621042_2 - - - - 0.000000000000002854 87.0
TLS2_k127_4657214_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.818e-244 760.0
TLS2_k127_4657214_1 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 357.0
TLS2_k127_4657214_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K04108 - 1.3.7.9 0.00001259 51.0
TLS2_k127_4692117_0 ABC transporter C-terminal domain K15738 - - 5.287e-235 744.0
TLS2_k127_4692117_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 477.0
TLS2_k127_4692117_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000001992 180.0
TLS2_k127_4692117_3 metalloaminopeptidase activity K01256,K07874,K08776,K13721,K17756 GO:0000322,GO:0000323,GO:0000324,GO:0000328,GO:0001666,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005768,GO:0005770,GO:0005771,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006073,GO:0006091,GO:0006112,GO:0006508,GO:0006518,GO:0006807,GO:0006810,GO:0006950,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009277,GO:0009628,GO:0009914,GO:0009926,GO:0009987,GO:0010013,GO:0010467,GO:0010817,GO:0012505,GO:0015980,GO:0016020,GO:0016485,GO:0016787,GO:0017171,GO:0019538,GO:0030287,GO:0030312,GO:0031090,GO:0031406,GO:0031410,GO:0031974,GO:0031982,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033554,GO:0034613,GO:0034641,GO:0036094,GO:0036293,GO:0036294,GO:0042221,GO:0042277,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043171,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043603,GO:0044042,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051716,GO:0055114,GO:0060918,GO:0061957,GO:0065007,GO:0065008,GO:0070006,GO:0070011,GO:0070013,GO:0070482,GO:0070727,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071944,GO:0072665,GO:0097159,GO:0097708,GO:0120113,GO:0140096,GO:1901564,GO:1901565,GO:1901575 1.1.3.20,3.4.11.2 0.0000000000000000329 92.0
TLS2_k127_4692117_4 - - - - 0.000000000000002111 84.0
TLS2_k127_4692117_5 MFS_1 like family - - - 0.00000000008718 75.0
TLS2_k127_4697800_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 543.0
TLS2_k127_4697800_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 469.0
TLS2_k127_4697800_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 440.0
TLS2_k127_4697800_3 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 400.0
TLS2_k127_4697800_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000217 295.0
TLS2_k127_4697800_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000002444 215.0
TLS2_k127_4697800_6 - - - - 0.00000000000000000000000000000000000000000000000000000006666 204.0
TLS2_k127_4697800_7 - - - - 0.00000000000000000000000000000000000000000000000000223 185.0
TLS2_k127_4697800_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000003034 111.0
TLS2_k127_4697800_9 Superinfection immunity protein - - - 0.00000002049 61.0
TLS2_k127_4708745_0 pfam abc1 K03688 - - 4.626e-254 797.0
TLS2_k127_4708745_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 9.74e-236 736.0
TLS2_k127_4708745_10 Belongs to the P(II) protein family - - - 0.0000003125 60.0
TLS2_k127_4708745_2 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 543.0
TLS2_k127_4708745_3 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 415.0
TLS2_k127_4708745_4 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 404.0
TLS2_k127_4708745_5 nucleotide catabolic process K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 334.0
TLS2_k127_4708745_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000000000001706 228.0
TLS2_k127_4708745_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000001474 143.0
TLS2_k127_4708745_9 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000000000000000003323 100.0
TLS2_k127_4730898_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 520.0
TLS2_k127_4730898_1 PFAM Transketolase central region K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 422.0
TLS2_k127_4730898_2 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 383.0
TLS2_k127_4730898_3 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 340.0
TLS2_k127_4730898_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002935 274.0
TLS2_k127_4730898_5 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000007498 62.0
TLS2_k127_4730898_6 Rhomboid family K02441 - - 0.000003743 58.0
TLS2_k127_4742052_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.339e-223 694.0
TLS2_k127_4742052_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 605.0
TLS2_k127_4742052_2 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 307.0
TLS2_k127_4742052_3 Electron transfer flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006214 251.0
TLS2_k127_4760619_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 586.0
TLS2_k127_4760619_1 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 373.0
TLS2_k127_4760619_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 323.0
TLS2_k127_4760619_3 TonB C terminal K03832 - - 0.00000003816 64.0
TLS2_k127_4760619_4 TonB C terminal K03832 - - 0.0004495 50.0
TLS2_k127_4772062_0 Belongs to the glycosyl hydrolase 57 family K06044 - 5.4.99.15 1.903e-307 966.0
TLS2_k127_4772062_1 Alpha amylase, catalytic domain K06044 - 5.4.99.15 8.329e-285 899.0
TLS2_k127_4772062_2 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 - 3.2.1.141 0.00000000000000000000000000000000000000000000000000000000007152 211.0
TLS2_k127_4777191_0 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 612.0
TLS2_k127_4777191_1 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 503.0
TLS2_k127_4777191_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 432.0
TLS2_k127_4777191_3 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 374.0
TLS2_k127_4777191_4 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 347.0
TLS2_k127_4777191_5 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000008352 180.0
TLS2_k127_4777191_6 Transposase - - - 0.000000001596 60.0
TLS2_k127_478410_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 608.0
TLS2_k127_478410_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 528.0
TLS2_k127_478410_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 399.0
TLS2_k127_478410_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 383.0
TLS2_k127_478410_4 PFAM SH3 type 3 K07184 - - 0.00000000000000000000000000000000000000000000000000000000006622 212.0
TLS2_k127_478410_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000003988 201.0
TLS2_k127_478410_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000316 203.0
TLS2_k127_478410_7 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000003379 196.0
TLS2_k127_4793386_0 phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 548.0
TLS2_k127_4793386_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 537.0
TLS2_k127_4793386_2 integral membrane protein - - - 0.00000000000000000000000000000000000000000157 178.0
TLS2_k127_4793386_3 ORF6N domain - - - 0.00000000000000000000000000000000001982 139.0
TLS2_k127_4793386_5 Monooxygenase fad-binding protein - - - 0.0000000000000000291 85.0
TLS2_k127_4810029_0 protein conserved in bacteria K09859 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 352.0
TLS2_k127_4810029_1 Peptidoglycan-synthase activator LpoB K07337 - - 0.0000000000000000000000000000000000000000000000000000000000000000007916 242.0
TLS2_k127_4810029_2 LPP20 lipoprotein - - - 0.000000000000000000000000000000000000008798 151.0
TLS2_k127_481424_0 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000001576 192.0
TLS2_k127_481424_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000008622 74.0
TLS2_k127_4867549_0 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 591.0
TLS2_k127_4867549_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 507.0
TLS2_k127_4867549_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 490.0
TLS2_k127_4867549_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 394.0
TLS2_k127_4867549_4 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000004004 244.0
TLS2_k127_4867549_5 PFAM CoA-binding domain protein - - - 0.00000000000000000000000000000000000002956 149.0
TLS2_k127_4867549_6 Regulatory protein, FmdB family - - - 0.000000000000000000000000000001627 124.0
TLS2_k127_4876366_0 PFAM phosphoesterase, RecJ domain protein - - - 1.081e-196 627.0
TLS2_k127_4876366_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000003978 113.0
TLS2_k127_4891375_0 Lanthionine synthetase C-like protein K20484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 305.0
TLS2_k127_4891375_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000001581 162.0
TLS2_k127_4901555_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 348.0
TLS2_k127_4901555_1 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000001943 230.0
TLS2_k127_4901555_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001768 222.0
TLS2_k127_4901555_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000003644 193.0
TLS2_k127_4901555_5 Transcriptional regulator - - - 0.0000000000000000000000000004885 122.0
TLS2_k127_4901555_6 - - - - 0.00000000000000000000003707 100.0
TLS2_k127_491903_0 Cytochrome C and Quinol oxidase polypeptide I K00404,K15862 - 1.9.3.1 4.8e-266 824.0
TLS2_k127_491903_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 587.0
TLS2_k127_491903_10 Domain of unknown function (DUF386) - - - 0.000000000000003554 86.0
TLS2_k127_491903_2 PFAM TraB determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 511.0
TLS2_k127_491903_3 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 407.0
TLS2_k127_491903_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 378.0
TLS2_k127_491903_5 PFAM AzlC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001215 291.0
TLS2_k127_491903_6 - K00673 - 2.3.1.109 0.000000000000000000000000000000000000000000000000000000000007419 215.0
TLS2_k127_491903_7 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000006938 115.0
TLS2_k127_491903_8 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000000000000005703 127.0
TLS2_k127_491903_9 Cytochrome c K00406 - - 0.0000000000000000005736 89.0
TLS2_k127_4920628_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1093.0
TLS2_k127_4920628_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000699 179.0
TLS2_k127_4920628_2 Amidohydrolase family - - - 0.000000000018 65.0
TLS2_k127_4922664_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 591.0
TLS2_k127_4922664_1 - - - - 0.0000000000000000000000000000000000000000000000000000409 193.0
TLS2_k127_4938382_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1170.0
TLS2_k127_4938382_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001063 261.0
TLS2_k127_4938382_2 regulation of cell shape K04074,K06997 - - 0.00000000000000000000000000000000000000000005414 166.0
TLS2_k127_4938382_3 Protein of unknown function (DUF494) K03747 - - 0.0000000000000000000000000000000000000001543 157.0
TLS2_k127_4938382_4 YGGT family K02221 - - 0.000000000000000000000000000000000001753 139.0
TLS2_k127_4938382_5 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000001964 114.0
TLS2_k127_4938382_6 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000001187 57.0
TLS2_k127_4972241_0 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753,K13818 - 2.7.7.77 1.574e-194 621.0
TLS2_k127_4972241_1 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 405.0
TLS2_k127_4972241_2 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000001885 97.0
TLS2_k127_4972241_3 Carboxymuconolactone decarboxylase family - - - 0.000003065 58.0
TLS2_k127_4981415_0 Domain of unknown function (DUF1848) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 305.0
TLS2_k127_4981415_1 glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001267 271.0
TLS2_k127_4981415_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000005653 209.0
TLS2_k127_4981415_3 CYTH K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000003358 198.0
TLS2_k127_4981415_4 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000008514 161.0
TLS2_k127_4981415_5 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000009825 149.0
TLS2_k127_4981415_6 - - - - 0.0000000000000000000000000000002903 137.0
TLS2_k127_4981415_7 PFAM thioesterase superfamily - - - 0.000000000000001421 89.0
TLS2_k127_5008281_0 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008537 249.0
TLS2_k127_5008281_1 PFAM Oxidoreductase FAD NAD(P)-binding - - - 0.0000000000000000000000000000000000000000000000000003062 194.0
TLS2_k127_5008281_2 surface antigen - - - 0.00000000000000000000000000000000000000003241 160.0
TLS2_k127_5008281_3 - - - - 0.000000000001565 78.0
TLS2_k127_501490_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 492.0
TLS2_k127_501490_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 401.0
TLS2_k127_501490_2 elongation factor Tu domain 2 protein K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 322.0
TLS2_k127_501490_4 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000003371 59.0
TLS2_k127_5018526_0 PFAM Histone deacetylase - - - 2.642e-240 756.0
TLS2_k127_5018526_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000306 305.0
TLS2_k127_5018526_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000005111 206.0
TLS2_k127_5018526_3 - - - - 0.00000000000000000000000000000001199 145.0
TLS2_k127_5050644_0 Ftsk_gamma K03466 - - 8.445e-208 669.0
TLS2_k127_5050644_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 335.0
TLS2_k127_5050644_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000001278 242.0
TLS2_k127_5050644_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000002122 164.0
TLS2_k127_5066299_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 370.0
TLS2_k127_5066299_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000009285 234.0
TLS2_k127_5085581_0 denitrification pathway - - - 1.458e-293 911.0
TLS2_k127_5085581_1 phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 441.0
TLS2_k127_5085581_2 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 295.0
TLS2_k127_5093861_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 2.259e-197 618.0
TLS2_k127_5093861_1 PFAM UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 552.0
TLS2_k127_5093861_2 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 492.0
TLS2_k127_5093861_3 dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000000000001418 212.0
TLS2_k127_5093861_4 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.00000004452 57.0
TLS2_k127_5100584_0 Fungalysin metallopeptidase (M36) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 469.0
TLS2_k127_5100584_1 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000009467 205.0
TLS2_k127_5100584_2 PFAM Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000000000000008544 192.0
TLS2_k127_5100584_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000001073 57.0
TLS2_k127_5100584_5 Protein conserved in bacteria - - - 0.0000001919 57.0
TLS2_k127_5138498_0 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 334.0
TLS2_k127_5138498_1 Pfam:DUF59 - - - 0.00000000000000000000000000000000000000000000000000000001536 203.0
TLS2_k127_5138498_2 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000003306 136.0
TLS2_k127_5141879_0 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 544.0
TLS2_k127_5141879_1 nitrogen compound transport K02033,K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 425.0
TLS2_k127_5141879_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 345.0
TLS2_k127_5141879_3 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000004064 226.0
TLS2_k127_5141879_4 Oligopeptide/dipeptide transporter, C-terminal region K02031,K15583 - - 0.000000000000000000000000000000000000000000000000046 199.0
TLS2_k127_5147763_0 Aminotransferase, class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 454.0
TLS2_k127_5147763_1 PFAM CBS domain containing protein K04767 - - 0.000000000000000000000000000000000002143 141.0
TLS2_k127_5147763_2 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000001049 92.0
TLS2_k127_5147763_3 PFAM CBS domain containing protein K04767 - - 0.000000000000001047 80.0
TLS2_k127_5147763_4 PFAM CBS domain containing protein K04767 - - 0.00000000002586 66.0
TLS2_k127_5206081_0 PFAM AAA ATPase central domain protein K06027 - 3.6.4.6 3.424e-277 859.0
TLS2_k127_5206081_1 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 315.0
TLS2_k127_5206081_3 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000123 290.0
TLS2_k127_5206081_4 Protein of unknown function (DUF1257) - - - 0.000000000000000000000000000000000000000000000000000004514 192.0
TLS2_k127_5207139_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1462.0
TLS2_k127_5207139_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 9.3e-304 950.0
TLS2_k127_5207139_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 550.0
TLS2_k127_5207139_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 392.0
TLS2_k127_5207139_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 286.0
TLS2_k127_5207139_5 Sensor histidine kinase, HAMP and PAS domain-containing - - - 0.000000000000000000000000000000000000000000000000001773 196.0
TLS2_k127_5207139_6 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.0000000000000000000000000000000000000000000000001701 191.0
TLS2_k127_5230379_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 372.0
TLS2_k127_5230379_1 PAS domain containing protein K03406,K13924,K14986 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000000000000000008544 124.0
TLS2_k127_5230379_2 - - - - 0.0002096 54.0
TLS2_k127_5249166_0 PFAM Dynamin family - - - 2.339e-231 737.0
TLS2_k127_5249166_1 SMART Elongator protein 3 MiaB NifB K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 390.0
TLS2_k127_5249166_2 SMART Metal-dependent phosphohydrolase, HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 337.0
TLS2_k127_5249166_3 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 299.0
TLS2_k127_5253909_0 Pilus assembly protein K02461,K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 376.0
TLS2_k127_5253909_1 Type II secretion system (T2SS), protein M K02462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004363 241.0
TLS2_k127_526248_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 487.0
TLS2_k127_526248_1 belongs to the nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 385.0
TLS2_k127_526248_2 Fumarate reductase flavoprotein C-term K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 349.0
TLS2_k127_526248_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000003298 222.0
TLS2_k127_5275066_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 434.0
TLS2_k127_5275066_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 389.0
TLS2_k127_5289959_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 634.0
TLS2_k127_5289959_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 406.0
TLS2_k127_5289959_2 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000001669 238.0
TLS2_k127_5295330_0 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000000000000002909 110.0
TLS2_k127_5301349_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000001946 232.0
TLS2_k127_5315195_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 4.942e-199 630.0
TLS2_k127_5315195_1 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 351.0
TLS2_k127_5315195_2 TIGRFAM lipopolysaccharide transport periplasmic protein LptA K09774 - - 0.0000000000000000000000001974 106.0
TLS2_k127_5319886_0 ATPase family associated with various cellular activities (AAA) - - - 0.0 1637.0
TLS2_k127_5319886_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5e-323 1000.0
TLS2_k127_5319886_2 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 516.0
TLS2_k127_5319886_3 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 308.0
TLS2_k127_5319886_4 Papain-like cysteine protease AvrRpt2 - - - 0.0000000000000000000000000000000000000000000000000000000000000004203 227.0
TLS2_k127_5319886_5 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000001859 186.0
TLS2_k127_5319886_6 Putative inner membrane exporter, YdcZ K09936 - - 0.0000000000000000000000000000000000000000000000002679 184.0
TLS2_k127_5319886_7 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000001167 128.0
TLS2_k127_5319886_8 - - - - 0.00000003448 65.0
TLS2_k127_5319886_9 - - - - 0.0000001608 63.0
TLS2_k127_5323761_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.508e-293 914.0
TLS2_k127_5323761_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 1.563e-271 840.0
TLS2_k127_5323761_10 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 325.0
TLS2_k127_5323761_11 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 317.0
TLS2_k127_5323761_12 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 326.0
TLS2_k127_5323761_13 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 301.0
TLS2_k127_5323761_14 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002618 245.0
TLS2_k127_5323761_15 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000002249 216.0
TLS2_k127_5323761_16 - - - - 0.000000000000000000000000000000000000000000008496 170.0
TLS2_k127_5323761_17 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000002115 163.0
TLS2_k127_5323761_18 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) - - - 0.000000000000000000000000000007891 124.0
TLS2_k127_5323761_19 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000003918 94.0
TLS2_k127_5323761_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 6.694e-231 723.0
TLS2_k127_5323761_3 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 2.691e-205 651.0
TLS2_k127_5323761_4 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 464.0
TLS2_k127_5323761_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 460.0
TLS2_k127_5323761_6 Cell surface protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 397.0
TLS2_k127_5323761_7 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 392.0
TLS2_k127_5323761_8 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 352.0
TLS2_k127_5323761_9 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 338.0
TLS2_k127_5343507_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.065e-242 764.0
TLS2_k127_5343507_1 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000000000000000000005687 163.0
TLS2_k127_5343507_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000001526 143.0
TLS2_k127_5360155_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.9e-237 738.0
TLS2_k127_5360155_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 469.0
TLS2_k127_5360155_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 422.0
TLS2_k127_5360155_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 314.0
TLS2_k127_5360155_4 Helix-turn-helix domain K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001063 275.0
TLS2_k127_5360155_5 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000003398 97.0
TLS2_k127_5360226_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 325.0
TLS2_k127_5360226_1 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000001851 216.0
TLS2_k127_5360226_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000001264 206.0
TLS2_k127_5360226_4 signal peptide peptidase SppA K04773 - - 0.0007674 51.0
TLS2_k127_5366548_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 3.374e-242 767.0
TLS2_k127_5366548_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000002575 188.0
TLS2_k127_5366548_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000002795 181.0
TLS2_k127_5366548_3 protein conserved in bacteria - - - 0.00000000000000131 90.0
TLS2_k127_5366548_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0001222 55.0
TLS2_k127_5373751_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.86e-202 646.0
TLS2_k127_5373751_1 Binding-protein-dependent transport system inner membrane component K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 583.0
TLS2_k127_5373751_2 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 548.0
TLS2_k127_5373751_3 Bacterial periplasmic substrate-binding proteins K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 554.0
TLS2_k127_5373751_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 484.0
TLS2_k127_5373751_5 ABC transporter K02028,K09972 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 434.0
TLS2_k127_5373751_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 319.0
TLS2_k127_5373751_7 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000009885 208.0
TLS2_k127_5373751_9 indolepyruvate ferredoxin oxidoreductase beta subunit K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000006792 171.0
TLS2_k127_5391506_0 AcrB/AcrD/AcrF family K03296,K07787 - - 0.0 1600.0
TLS2_k127_5391506_1 Mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 449.0
TLS2_k127_5391506_2 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 421.0
TLS2_k127_5391506_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 377.0
TLS2_k127_5391506_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07798 - - 0.00000000000000000000000000000000000000001355 158.0
TLS2_k127_5391506_5 - - - - 0.000000000000000000000000000000001224 137.0
TLS2_k127_5391784_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1043.0
TLS2_k127_5391784_1 PFAM UvrD REP helicase K03656,K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 535.0
TLS2_k127_5391784_2 phosphoribosyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008634 255.0
TLS2_k127_5391784_3 Chemotaxis protein cheY K03413 - - 0.000000000000000000000000000000000000000000000000000003684 193.0
TLS2_k127_5391784_4 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000001471 181.0
TLS2_k127_5391784_5 tRNA modification K06968 - 2.1.1.186 0.000000000000000000000000000000000000000000000003327 180.0
TLS2_k127_5391784_6 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.000000000000000000000000003256 113.0
TLS2_k127_5416705_0 Belongs to the ABC transporter superfamily K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 8.96e-229 721.0
TLS2_k127_5416705_1 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 338.0
TLS2_k127_5416989_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 6.711e-195 617.0
TLS2_k127_5416989_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 419.0
TLS2_k127_5416989_2 - - - - 0.00000001255 62.0
TLS2_k127_5444738_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1261.0
TLS2_k127_5444738_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 448.0
TLS2_k127_5444738_2 ligase activity, forming carbon-carbon bonds K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 422.0
TLS2_k127_5444738_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001038 246.0
TLS2_k127_5444738_4 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000262 167.0
TLS2_k127_5454119_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 468.0
TLS2_k127_5454119_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 295.0
TLS2_k127_5454119_2 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000004044 125.0
TLS2_k127_5454119_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000004801 72.0
TLS2_k127_5480596_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1204.0
TLS2_k127_5480596_1 helicase domain protein - - - 1.488e-289 922.0
TLS2_k127_5480596_3 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000003923 160.0
TLS2_k127_5506488_0 Sodium/hydrogen exchanger family - - - 8.953e-269 846.0
TLS2_k127_5506488_1 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000143 239.0
TLS2_k127_5588267_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 461.0
TLS2_k127_5588267_1 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 355.0
TLS2_k127_5588267_2 transport system involved in gliding motility, auxiliary K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 331.0
TLS2_k127_5588267_3 PFAM Amino acid - - - 0.00000000000000000000000000000000000000000000000000000000001047 214.0
TLS2_k127_5588267_4 DNA polymerase III chi subunit, HolC K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000001152 206.0
TLS2_k127_5596322_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 3.848e-199 630.0
TLS2_k127_5596322_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 380.0
TLS2_k127_5596322_10 Protein of unknown function (DUF3307) - - - 0.00000000000000209 87.0
TLS2_k127_5596322_11 - - - - 0.000000000000002515 83.0
TLS2_k127_5596322_2 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 340.0
TLS2_k127_5596322_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 332.0
TLS2_k127_5596322_4 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 323.0
TLS2_k127_5596322_5 PFAM Cytochrome b5 - - - 0.000000000000000000000000000000000000000000000000000000000000005744 229.0
TLS2_k127_5596322_6 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000002252 176.0
TLS2_k127_5596322_7 - - - - 0.000000000000000000000000000000000000001235 154.0
TLS2_k127_5596322_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000002142 128.0
TLS2_k127_5596322_9 SatD family (SatD) - - - 0.0000000000000006251 88.0
TLS2_k127_5613315_0 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 346.0
TLS2_k127_5613315_1 A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001364 276.0
TLS2_k127_5613315_2 Cupin domain - - - 0.0000000000000000000000000000000000000001497 152.0
TLS2_k127_5628245_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 367.0
TLS2_k127_5628245_2 Protein of unknown function (DUF554) K07150 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003726 255.0
TLS2_k127_5628245_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007659 233.0
TLS2_k127_5628245_5 Zinc transporter ZupT K07238 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874 - 0.00000000000000000000000000000000001572 145.0
TLS2_k127_5628245_6 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000006666 112.0
TLS2_k127_5628245_7 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000002097 75.0
TLS2_k127_5628245_8 Cupin domain - - - 0.00000000549 62.0
TLS2_k127_5631993_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1414.0
TLS2_k127_5631993_1 Cache domain K10125 - 2.7.13.3 0.000000000000000000000000005618 130.0
TLS2_k127_5655581_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1529.0
TLS2_k127_5655581_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 554.0
TLS2_k127_5655581_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 463.0
TLS2_k127_5655581_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 364.0
TLS2_k127_5655581_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 339.0
TLS2_k127_5655581_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 310.0
TLS2_k127_5655581_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002665 286.0
TLS2_k127_5655581_7 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000000000000002647 212.0
TLS2_k127_5655581_8 - - - - 0.000000000000000000000000000000002765 144.0
TLS2_k127_5655581_9 EamA-like transporter family - - - 0.00000000000000000001369 95.0
TLS2_k127_5656546_0 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 0.0 1210.0
TLS2_k127_5656546_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.395e-254 831.0
TLS2_k127_5656546_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 598.0
TLS2_k127_5656546_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 574.0
TLS2_k127_5656546_4 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 453.0
TLS2_k127_5656546_5 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 462.0
TLS2_k127_5656546_6 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 343.0
TLS2_k127_5656546_7 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 342.0
TLS2_k127_5697083_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1836.0
TLS2_k127_5697083_1 Belongs to the CarA family K01956 - 6.3.5.5 4.498e-202 654.0
TLS2_k127_5697083_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 609.0
TLS2_k127_5701439_0 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 460.0
TLS2_k127_5701439_1 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000001633 144.0
TLS2_k127_5701439_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000007647 109.0
TLS2_k127_5701439_3 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000002001 89.0
TLS2_k127_5730477_0 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 339.0
TLS2_k127_5730477_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003337 244.0
TLS2_k127_5730477_2 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000001953 242.0
TLS2_k127_5730477_4 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.0000000000000000000000005457 117.0
TLS2_k127_5730477_5 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000000000000000005534 86.0
TLS2_k127_5748306_0 Bacterial regulatory protein, Fis family - - - 2.837e-230 721.0
TLS2_k127_5748306_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000467 154.0
TLS2_k127_5748306_2 Belongs to the bacterial histone-like protein family K05788 - - 0.0000000000000000000000000000005321 125.0
TLS2_k127_5750058_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 1.556e-289 897.0
TLS2_k127_5750058_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 8.75e-206 664.0
TLS2_k127_5750058_2 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 512.0
TLS2_k127_5750058_3 heat shock protein binding - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 414.0
TLS2_k127_5750058_4 PFAM 4Fe-4S ferredoxin K08358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 366.0
TLS2_k127_5750058_5 acyl-coa dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 351.0
TLS2_k127_5758318_0 FAD dependent oxidoreductase K07137 - - 1.739e-203 651.0
TLS2_k127_5758318_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 333.0
TLS2_k127_5758318_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000001046 241.0
TLS2_k127_5758318_3 PFAM conserved K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000049 194.0
TLS2_k127_5758318_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000003735 196.0
TLS2_k127_5760694_0 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 357.0
TLS2_k127_5760694_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 325.0
TLS2_k127_5760694_2 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000005927 132.0
TLS2_k127_5776684_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 8.454e-293 902.0
TLS2_k127_5776684_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.304e-282 873.0
TLS2_k127_5776684_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.961e-245 761.0
TLS2_k127_5776684_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 572.0
TLS2_k127_5776684_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002068 290.0
TLS2_k127_5776684_5 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000002264 261.0
TLS2_k127_5790283_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000002274 232.0
TLS2_k127_5790283_1 - K18700 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042802,GO:0042803,GO:0046983 3.1.2.29 0.00000000000000000000000000000000000000000000000000007419 191.0
TLS2_k127_5790283_2 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000000001664 174.0
TLS2_k127_5800574_0 PFAM Extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 377.0
TLS2_k127_5800574_1 transporter, DctM subunit K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 341.0
TLS2_k127_5800574_2 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 321.0
TLS2_k127_5800574_3 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000001603 256.0
TLS2_k127_5800574_4 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000003728 178.0
TLS2_k127_5800574_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000006682 120.0
TLS2_k127_5800706_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 603.0
TLS2_k127_5800706_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 424.0
TLS2_k127_5800706_2 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 323.0
TLS2_k127_5800706_3 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000001302 233.0
TLS2_k127_5800706_4 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000001801 160.0
TLS2_k127_5819018_0 Monooxygenase fad-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 349.0
TLS2_k127_5819018_1 Beta-lactamase superfamily domain - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.00000000000000000000000000000000000000000000000009682 187.0
TLS2_k127_5819018_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000009527 177.0
TLS2_k127_5824218_0 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 517.0
TLS2_k127_5824218_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 488.0
TLS2_k127_5824218_2 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000000000003646 139.0
TLS2_k127_5827888_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 374.0
TLS2_k127_5845313_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 503.0
TLS2_k127_5845313_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 434.0
TLS2_k127_5845313_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 409.0
TLS2_k127_5845313_3 ABC-2 family transporter protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 351.0
TLS2_k127_5845313_4 GGDEF domain K01768 - 4.6.1.1 0.0000000000000000000000000000001613 135.0
TLS2_k127_5845313_6 PFAM Outer membrane lipoprotein Slp K07285 - - 0.0000000000000000000001713 108.0
TLS2_k127_5851609_0 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 503.0
TLS2_k127_5851609_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 339.0
TLS2_k127_5851609_2 - - - - 0.000000000000000000000000000000000000000005895 160.0
TLS2_k127_5851609_3 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.0000000000000000000000000000000000001648 144.0
TLS2_k127_5851609_4 - - - - 0.0000000000000000000000000000000000003232 145.0
TLS2_k127_5851609_5 - - - - 0.000000000000000000000000000000000002463 141.0
TLS2_k127_5868379_0 aconitate hydratase K01681 - 4.2.1.3 5.194e-297 928.0
TLS2_k127_5868379_1 Belongs to the RtcB family K14415 - 6.5.1.3 2.929e-248 775.0
TLS2_k127_5868379_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 2.135e-208 674.0
TLS2_k127_5868379_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 386.0
TLS2_k127_5868379_4 reductase K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 338.0
TLS2_k127_5868379_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 338.0
TLS2_k127_5868379_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 314.0
TLS2_k127_5868379_7 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 329.0
TLS2_k127_5868379_8 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000002328 98.0
TLS2_k127_5877330_0 Alpha beta hydrolase K03821 - - 2.265e-250 785.0
TLS2_k127_5877330_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000007913 128.0
TLS2_k127_5881031_0 - K11918 - - 0.00000000000000000001728 99.0
TLS2_k127_5881031_1 Type VI secretion system protein DotU K11892 - - 0.000000000000002476 87.0
TLS2_k127_5905854_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 391.0
TLS2_k127_5905854_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 332.0
TLS2_k127_5905854_2 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000000000000000000006408 196.0
TLS2_k127_5905854_3 Rhodanese Homology Domain - - - 0.0000000000001042 83.0
TLS2_k127_5912638_0 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000000000000000000000000000000000000000005169 166.0
TLS2_k127_5912638_1 - - - - 0.0000000000000000000000000000000000000131 147.0
TLS2_k127_5912638_2 - - - - 0.0000000000000000009591 94.0
TLS2_k127_5912638_3 - - - - 0.0000000000001918 73.0
TLS2_k127_5913931_0 Polysaccharide biosynthesis protein CapD - - - 1.287e-194 627.0
TLS2_k127_5913931_1 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 513.0
TLS2_k127_5913931_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 323.0
TLS2_k127_5913931_3 PFAM Glycosyl transferase family 4 K13007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007271 269.0
TLS2_k127_5913931_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000002157 198.0
TLS2_k127_5913931_5 Addiction module toxin, RelE StbE family - - - 0.0000000000000000003684 94.0
TLS2_k127_5913931_6 toxin-antitoxin pair type II binding - - - 0.00000000000000001128 86.0
TLS2_k127_5914270_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.082e-296 923.0
TLS2_k127_5914270_1 alpha amylase catalytic K01182,K05343 - 3.2.1.1,3.2.1.10,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 316.0
TLS2_k127_5927559_0 PFAM Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 325.0
TLS2_k127_5927559_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 326.0
TLS2_k127_5936280_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 614.0
TLS2_k127_5936280_1 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 523.0
TLS2_k127_5936280_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 392.0
TLS2_k127_5936280_3 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 316.0
TLS2_k127_5936280_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000003279 238.0
TLS2_k127_5936280_5 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000007724 215.0
TLS2_k127_5936280_6 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000002362 199.0
TLS2_k127_5936280_7 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.0000000000000000000000000000000000000000000000004351 181.0
TLS2_k127_5936280_8 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000003882 164.0
TLS2_k127_5937132_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1118.0
TLS2_k127_5937132_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 328.0
TLS2_k127_5937132_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 326.0
TLS2_k127_5937132_3 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 321.0
TLS2_k127_5937132_4 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004376 269.0
TLS2_k127_5937132_5 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000001223 93.0
TLS2_k127_5937132_6 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000009978 77.0
TLS2_k127_5946615_0 lipid kinase activity - - - 0.00000000000000000000000000000004003 135.0
TLS2_k127_5946615_1 Methyltransferase K00587 - 2.1.1.100 0.000009703 55.0
TLS2_k127_5950884_0 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 298.0
TLS2_k127_5950884_1 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000000000000000000000000002217 240.0
TLS2_k127_598338_0 cytochrome c peroxidase - - - 8.827e-246 779.0
TLS2_k127_598338_1 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 501.0
TLS2_k127_598338_2 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 436.0
TLS2_k127_598338_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007906 263.0
TLS2_k127_598338_4 - - - - 0.00000000000000000000000000000000000000000000002336 186.0
TLS2_k127_598338_5 - - - - 0.00005907 49.0
TLS2_k127_5986456_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 304.0
TLS2_k127_5986456_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002168 266.0
TLS2_k127_5986456_2 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000001178 213.0
TLS2_k127_5986456_3 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.00000000000000000000000000000000000000000000008401 184.0
TLS2_k127_5986456_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000003861 51.0
TLS2_k127_6002316_0 cysteine-tRNA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 466.0
TLS2_k127_6002316_1 Glycosyl transferase group 1 K00696,K13058 GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,2.4.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 353.0
TLS2_k127_6002316_2 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 304.0
TLS2_k127_6002316_3 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001474 278.0
TLS2_k127_6002316_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001059 251.0
TLS2_k127_6002316_5 virion core protein (lumpy skin disease virus) - - - 0.000000000000000000000000000000000008379 137.0
TLS2_k127_6005074_0 TRAP transporter, 4TM 12TM fusion protein - - - 1.988e-316 987.0
TLS2_k127_6005074_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 1.518e-211 664.0
TLS2_k127_6005074_2 PFAM Prokaryotic protein of K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 469.0
TLS2_k127_6005074_3 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 473.0
TLS2_k127_6005074_4 Helix-turn-helix domain, rpiR family - - - 0.0000000000000000000000000005751 115.0
TLS2_k127_6026616_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 8.807e-222 706.0
TLS2_k127_6026616_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02621 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 430.0
TLS2_k127_602780_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000001151 174.0
TLS2_k127_6040327_0 Adenylate cyclase K05851 - 4.6.1.1 2.011e-205 662.0
TLS2_k127_606881_0 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 468.0
TLS2_k127_606881_1 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 461.0
TLS2_k127_606881_10 Flagellar biosynthetic protein FliQ K02420,K03227 - - 0.0000000000000000000000000000367 126.0
TLS2_k127_606881_11 PFAM CheW domain protein K03408 - - 0.0000000000000000000000001996 111.0
TLS2_k127_606881_12 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000000000000008777 106.0
TLS2_k127_606881_13 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000001018 99.0
TLS2_k127_606881_14 Belongs to the flagella basal body rod proteins family K02391,K02392 - - 0.00000000002112 71.0
TLS2_k127_606881_15 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.00000000182 64.0
TLS2_k127_606881_16 PFAM FlhB HrpN YscU SpaS Family K04061 - - 0.00000001162 60.0
TLS2_k127_606881_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009658 431.0
TLS2_k127_606881_3 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 376.0
TLS2_k127_606881_4 CheR methyltransferase, SAM binding domain K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 333.0
TLS2_k127_606881_5 flagellar biosynthetic protein FliR K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 317.0
TLS2_k127_606881_6 two component, sigma54 specific, transcriptional regulator, Fis family K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000106 236.0
TLS2_k127_606881_7 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000000000000000000000000002704 184.0
TLS2_k127_606881_8 AMP binding - - - 0.00000000000000000000000000000000000000000000002112 176.0
TLS2_k127_608524_0 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 444.0
TLS2_k127_608524_1 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000008481 217.0
TLS2_k127_608524_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000001972 156.0
TLS2_k127_608524_3 NUDIX domain - - - 0.00000000000000000000000000000000001249 146.0
TLS2_k127_608524_5 Protein of unknown function (DUF1614) - - - 0.000000006571 56.0
TLS2_k127_6089033_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 9.159e-300 928.0
TLS2_k127_6089033_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 9.035e-229 716.0
TLS2_k127_6089033_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 390.0
TLS2_k127_6089033_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 309.0
TLS2_k127_6089033_4 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000007311 196.0
TLS2_k127_6089033_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.0000000000000000000000000000000000000005602 154.0
TLS2_k127_6101062_0 SMART Elongator protein 3 MiaB NifB - - - 0.0 1108.0
TLS2_k127_6101062_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1012.0
TLS2_k127_6101062_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 610.0
TLS2_k127_6118973_0 3'-5' exonuclease K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001549 284.0
TLS2_k127_6118973_1 - - - - 0.0000000000004626 80.0
TLS2_k127_6124370_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 1.836e-246 769.0
TLS2_k127_6124370_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000932 601.0
TLS2_k127_6124370_10 Las17-binding protein actin regulator - - - 0.00000000001094 67.0
TLS2_k127_6124370_2 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 579.0
TLS2_k127_6124370_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 479.0
TLS2_k127_6124370_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 349.0
TLS2_k127_6124370_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000002353 259.0
TLS2_k127_6124370_6 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000002452 221.0
TLS2_k127_6124370_7 Histidine phosphatase superfamily (branch 1) K08296 - - 0.00000000000000000000000000001081 124.0
TLS2_k127_6124370_9 PilZ domain - - - 0.000000000000000009738 87.0
TLS2_k127_6125144_0 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 6.726e-203 640.0
TLS2_k127_6125144_1 Poly A polymerase, head domain K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 520.0
TLS2_k127_6144519_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 7.96e-292 906.0
TLS2_k127_6144519_1 PFAM Hydantoinase oxoprolinase - - - 2.976e-221 702.0
TLS2_k127_6144519_2 PFAM Histone deacetylase K04768 - - 8.789e-221 692.0
TLS2_k127_6144519_3 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000005702 51.0
TLS2_k127_6163708_0 PFAM MMPL family K07003 - - 0.0 1257.0
TLS2_k127_6163708_1 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 400.0
TLS2_k127_6163708_2 Receptor - - - 0.000000000000001057 79.0
TLS2_k127_6170059_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 539.0
TLS2_k127_6170059_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 446.0
TLS2_k127_6170059_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 317.0
TLS2_k127_6171317_0 PFAM Carbamoyltransferase K00612 - - 1.013e-265 830.0
TLS2_k127_6171317_1 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000000005329 209.0
TLS2_k127_6171317_2 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000001465 174.0
TLS2_k127_6171317_3 Peptidase family S58 - - - 0.00000000000000000000000000000000000004662 148.0
TLS2_k127_6171317_4 Predicted membrane protein (DUF2318) K09005 - - 0.00000000001457 71.0
TLS2_k127_6180975_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 526.0
TLS2_k127_6180975_1 Thiamine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 505.0
TLS2_k127_6180975_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000003554 168.0
TLS2_k127_6197188_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 1.137e-316 975.0
TLS2_k127_6197188_1 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 546.0
TLS2_k127_6197188_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 452.0
TLS2_k127_6197188_3 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 357.0
TLS2_k127_6197188_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 351.0
TLS2_k127_6197188_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008467 258.0
TLS2_k127_6197188_6 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000007058 192.0
TLS2_k127_6197188_7 peptidyl-prolyl cis-trans isomerase activity K00645,K02597,K03769,K03771 - 2.3.1.39,5.2.1.8 0.0000000000000000000000000001218 126.0
TLS2_k127_6198947_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 486.0
TLS2_k127_6198947_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006039 305.0
TLS2_k127_6198947_2 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000003352 227.0
TLS2_k127_6198947_3 - - - - 0.0000000000000000000000000000000000000000000000008253 186.0
TLS2_k127_6198947_4 Predicted membrane protein (DUF2335) - - - 0.000000000000000000005394 99.0
TLS2_k127_6198947_5 domain, Protein K13874,K22217 - 3.1.1.15 0.00000000000000000006114 104.0
TLS2_k127_6198947_6 Glycosyl transferases group 1 K00786 - - 0.000000000000000005086 96.0
TLS2_k127_6198947_7 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.00000000001193 77.0
TLS2_k127_6198947_8 - - - - 0.0000000171 63.0
TLS2_k127_6199607_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1245.0
TLS2_k127_6199607_1 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 503.0
TLS2_k127_6203740_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.533e-194 617.0
TLS2_k127_6203740_1 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 488.0
TLS2_k127_6203740_2 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 392.0
TLS2_k127_6203740_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 361.0
TLS2_k127_6203740_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008658 246.0
TLS2_k127_6203740_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000008494 237.0
TLS2_k127_6203740_6 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000321 145.0
TLS2_k127_6203740_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000001704 125.0
TLS2_k127_6203740_8 Dodecin K09165 - - 0.00000000000000000000000000003453 121.0
TLS2_k127_6214522_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 441.0
TLS2_k127_6214522_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 430.0
TLS2_k127_6214522_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000006929 195.0
TLS2_k127_6214522_3 Redoxin - - - 0.00000000000000000000000000000000000001149 148.0
TLS2_k127_6214522_4 Redoxin - - - 0.000000000000000003667 87.0
TLS2_k127_6214522_5 Pfam SNARE associated Golgi protein - - - 0.00000000000000005979 84.0
TLS2_k127_6237313_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.0 1196.0
TLS2_k127_6237313_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 471.0
TLS2_k127_6237313_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000004291 132.0
TLS2_k127_6237313_3 Osmosensitive K channel K07646 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0008134,GO:0008150,GO:0008152,GO:0009593,GO:0009605,GO:0009628,GO:0009651,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031668,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051606,GO:0051716,GO:0065007,GO:0071214,GO:0071470,GO:0071472,GO:0071496,GO:0071704,GO:0071944,GO:0104004,GO:0140096,GO:1901564 2.7.13.3 0.0000000000001987 82.0
TLS2_k127_6257020_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 5.354e-258 823.0
TLS2_k127_6257020_1 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 590.0
TLS2_k127_6257020_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 553.0
TLS2_k127_6257020_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 458.0
TLS2_k127_6257020_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009875 279.0
TLS2_k127_6257020_5 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000000000000000001195 158.0
TLS2_k127_6258143_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.964e-260 807.0
TLS2_k127_6258143_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 551.0
TLS2_k127_6258143_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 385.0
TLS2_k127_6258143_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001895 280.0
TLS2_k127_6258143_4 transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003705 274.0
TLS2_k127_6258143_5 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000002194 133.0
TLS2_k127_6262939_0 PFAM Radical SAM - - - 5.118e-211 670.0
TLS2_k127_6262939_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 2.139e-209 662.0
TLS2_k127_6262939_2 UPF0365 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 493.0
TLS2_k127_6262939_3 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 466.0
TLS2_k127_6262939_4 PFAM Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 383.0
TLS2_k127_6262939_5 Serine aminopeptidase, S33 K06889 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000144 266.0
TLS2_k127_6262939_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001414 261.0
TLS2_k127_6262939_7 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000000000000000003196 203.0
TLS2_k127_6262939_8 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000004785 121.0
TLS2_k127_627700_0 Peptidase M16C associated K06972 - - 1.978e-235 745.0
TLS2_k127_627700_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 371.0
TLS2_k127_627700_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 342.0
TLS2_k127_627700_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 299.0
TLS2_k127_627700_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002255 254.0
TLS2_k127_6278877_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 548.0
TLS2_k127_6278877_1 decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 461.0
TLS2_k127_6278877_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 349.0
TLS2_k127_6278877_3 HNH nucleases - - - 0.0000000000000000000000000000000000000000002787 166.0
TLS2_k127_6361227_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 5.522e-194 611.0
TLS2_k127_6361227_1 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 429.0
TLS2_k127_6361227_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 412.0
TLS2_k127_6361227_3 CBS domain containing protein K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000004251 259.0
TLS2_k127_6361227_4 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000000000000000000002256 235.0
TLS2_k127_6368917_0 PFAM peptidase U32 K08303 - - 2.279e-221 713.0
TLS2_k127_6368917_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 303.0
TLS2_k127_6368917_2 DNA topoisomerase type I activity - - - 0.00000000000000000000000000000000000000000001591 164.0
TLS2_k127_6368917_3 Transposase and inactivated derivatives - - - 0.000000000000000000000000005956 115.0
TLS2_k127_6368917_4 cell redox homeostasis - - - 0.000000000000000000000002187 112.0
TLS2_k127_6370259_0 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 310.0
TLS2_k127_6370259_1 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 305.0
TLS2_k127_6370259_2 negative regulation of phosphate transmembrane transport K01104,K02039,K03741 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 0.000000000000000000000000000000000000001148 166.0
TLS2_k127_6370259_3 Nudix N-terminal - - - 0.00000000000000000000000000000000000005901 160.0
TLS2_k127_6370259_4 Na dependent nucleoside transporter K03317 - - 0.000000003673 57.0
TLS2_k127_6384067_0 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 396.0
TLS2_k127_6384067_2 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 300.0
TLS2_k127_6384067_3 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002977 281.0
TLS2_k127_6384067_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000008036 205.0
TLS2_k127_6384067_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000002673 187.0
TLS2_k127_6384067_7 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000008799 140.0
TLS2_k127_6401020_0 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.0 1015.0
TLS2_k127_6401020_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 4.517e-226 707.0
TLS2_k127_6401020_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001518 262.0
TLS2_k127_6401020_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000001007 182.0
TLS2_k127_6401020_4 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000005837 180.0
TLS2_k127_642082_0 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 531.0
TLS2_k127_642082_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 485.0
TLS2_k127_642082_2 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 425.0
TLS2_k127_642082_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000002066 54.0
TLS2_k127_643023_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.318e-205 644.0
TLS2_k127_643023_1 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 312.0
TLS2_k127_643023_2 purine-nucleoside phosphorylase activity K00772,K03784 GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
TLS2_k127_6433002_0 acetyl-CoA hydrolase transferase - - - 0.0 1027.0
TLS2_k127_6433002_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 602.0
TLS2_k127_6433002_2 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 551.0
TLS2_k127_6433002_3 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 368.0
TLS2_k127_6433002_4 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 339.0
TLS2_k127_6433002_5 Etoposide-induced protein 2.4 (EI24) K06203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009775 269.0
TLS2_k127_6433002_6 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000002373 226.0
TLS2_k127_6433002_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000003339 198.0
TLS2_k127_6433002_8 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000006191 161.0
TLS2_k127_6439735_0 PFAM Type II secretion system protein E K02454 - - 1.587e-250 787.0
TLS2_k127_6439735_1 Type II and III secretion system protein K02453 - - 8.903e-209 662.0
TLS2_k127_6439735_2 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 535.0
TLS2_k127_6439735_3 PFAM PHP domain protein K02347,K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 346.0
TLS2_k127_6439735_4 Type II secretion system protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 294.0
TLS2_k127_6439735_5 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004622 260.0
TLS2_k127_6444176_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.714e-213 672.0
TLS2_k127_6444176_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 2.881e-213 674.0
TLS2_k127_6444176_2 SMART Elongator protein 3 MiaB NifB K22227 - - 2.148e-211 660.0
TLS2_k127_6444176_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 492.0
TLS2_k127_6444176_4 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 449.0
TLS2_k127_6444176_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 286.0
TLS2_k127_6461251_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 3.31e-310 973.0
TLS2_k127_6461251_1 metal-dependent phosphohydrolase HD region - - - 1.891e-201 638.0
TLS2_k127_6461251_2 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000001263 195.0
TLS2_k127_6518334_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 8.76e-201 638.0
TLS2_k127_6518334_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 362.0
TLS2_k127_6525249_0 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 371.0
TLS2_k127_6525249_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001722 247.0
TLS2_k127_657678_0 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 476.0
TLS2_k127_657678_1 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 387.0
TLS2_k127_657678_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 380.0
TLS2_k127_657678_3 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 291.0
TLS2_k127_657678_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000744 286.0
TLS2_k127_657678_5 Ferritin Dps family protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000173 278.0
TLS2_k127_657678_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000217 175.0
TLS2_k127_657678_7 PFAM CBS domain containing protein K04767 - - 0.0000000000000000000000000000000000007706 148.0
TLS2_k127_657678_8 - - - - 0.00000000000000000000000000005773 124.0
TLS2_k127_6596772_0 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 560.0
TLS2_k127_6596772_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 451.0
TLS2_k127_6596772_2 TIGRFAM cysteine K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 419.0
TLS2_k127_6596772_3 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 298.0
TLS2_k127_6596772_4 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.00000000000000000000000000000000000000000000000000002202 197.0
TLS2_k127_6603542_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.043e-314 967.0
TLS2_k127_6603542_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 473.0
TLS2_k127_6603542_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 398.0
TLS2_k127_6603542_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000000001753 268.0
TLS2_k127_6610415_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000007175 160.0
TLS2_k127_6610415_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000005793 117.0
TLS2_k127_6610415_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000006158 98.0
TLS2_k127_6610415_3 Regulatory protein - - - 0.000000000000000000007303 98.0
TLS2_k127_6610415_4 - - - - 0.000000000000000001825 99.0
TLS2_k127_6610415_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000007411 71.0
TLS2_k127_6623298_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 580.0
TLS2_k127_6623298_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 480.0
TLS2_k127_6623298_2 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 327.0
TLS2_k127_6623298_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000001448 197.0
TLS2_k127_6623298_4 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.000000000000000000000000000000001764 135.0
TLS2_k127_6623298_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000007715 102.0
TLS2_k127_6623298_6 Fibronectin type 3 domain K01637 - 4.1.3.1 0.0000004369 60.0
TLS2_k127_6626064_0 FAD dependent oxidoreductase K07137 - - 2.117e-202 645.0
TLS2_k127_6626064_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 447.0
TLS2_k127_6635123_0 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 449.0
TLS2_k127_6635123_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 346.0
TLS2_k127_6635123_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 310.0
TLS2_k127_6635123_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000002137 144.0
TLS2_k127_6635123_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000002057 128.0
TLS2_k127_6637419_0 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 439.0
TLS2_k127_6637419_1 Glutamine cyclotransferase K00683 - 2.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006279 284.0
TLS2_k127_6641970_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 5.07e-276 856.0
TLS2_k127_6641970_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 5.128e-224 715.0
TLS2_k127_6641970_10 protein family UPF0079, ATPase K06925 - - 0.0000000000000000000000000000000000000000000004907 179.0
TLS2_k127_6641970_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000005001 119.0
TLS2_k127_6641970_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 1.842e-212 677.0
TLS2_k127_6641970_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 547.0
TLS2_k127_6641970_4 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 525.0
TLS2_k127_6641970_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 376.0
TLS2_k127_6641970_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 369.0
TLS2_k127_6641970_7 PFAM YbbR family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008751 327.0
TLS2_k127_6641970_8 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000009583 196.0
TLS2_k127_6641970_9 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000001315 173.0
TLS2_k127_6662803_0 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 440.0
TLS2_k127_6662803_1 PFAM permease K07089 - - 0.0000000000000000000000000000000000000000000000002686 183.0
TLS2_k127_6662803_2 - - - - 0.0000000000000000000000000000000000000000000003155 170.0
TLS2_k127_6662803_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000004293 160.0
TLS2_k127_6673704_0 PFAM Polysaccharide export protein - - - 0.0 1214.0
TLS2_k127_6673704_1 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 591.0
TLS2_k127_667761_0 MacB-like periplasmic core domain K02004 - - 1.4e-213 678.0
TLS2_k127_667761_1 PFAM WD40 domain protein beta Propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 541.0
TLS2_k127_667761_2 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 470.0
TLS2_k127_667761_4 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division K08306 - - 0.00002448 56.0
TLS2_k127_6692466_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 2.139e-205 647.0
TLS2_k127_6692466_1 PFAM isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 586.0
TLS2_k127_6692466_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 544.0
TLS2_k127_6692466_3 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 358.0
TLS2_k127_6692466_4 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000001583 243.0
TLS2_k127_6692466_5 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001861 249.0
TLS2_k127_6692466_6 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000182 124.0
TLS2_k127_6692466_7 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000313 77.0
TLS2_k127_6697139_0 CBS domain containing protein K00974 - 2.7.7.72 1.873e-269 847.0
TLS2_k127_6697139_1 Histidine kinase - - - 1.377e-252 791.0
TLS2_k127_6697139_2 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 343.0
TLS2_k127_6697139_3 SMART Metal-dependent phosphohydrolase, HD region K07023 - - 0.00000000000000000000000000000000000000000000000205 183.0
TLS2_k127_6698340_0 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 296.0
TLS2_k127_6698340_1 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007272 289.0
TLS2_k127_6698340_2 PFAM UvrD REP helicase K03656,K03657 - 3.6.4.12 0.0000000000000000000000000000000000001554 143.0
TLS2_k127_6698340_3 - - - - 0.00000000000000000000000001087 115.0
TLS2_k127_6698340_4 Alpha beta hydrolase - - - 0.00000000000000000001027 94.0
TLS2_k127_674981_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 532.0
TLS2_k127_674981_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 496.0
TLS2_k127_674981_2 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 457.0
TLS2_k127_674981_3 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 351.0
TLS2_k127_6752555_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 3.686e-195 629.0
TLS2_k127_6752555_1 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000001919 233.0
TLS2_k127_6752555_2 DoxX K15977 - - 0.00000000000000000000000000000000000000000001876 166.0
TLS2_k127_6764506_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0 1204.0
TLS2_k127_6764506_1 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 561.0
TLS2_k127_6764506_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 421.0
TLS2_k127_6764506_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 383.0
TLS2_k127_6764506_4 - - - - 0.000000000000000000000000000000000002862 139.0
TLS2_k127_6764506_5 Protein of unknown function (DUF3108) - - - 0.0000000002863 62.0
TLS2_k127_6784700_0 NADH flavin oxidoreductase NADH oxidase - - - 0.0 1105.0
TLS2_k127_6784700_1 HI0933-like protein K00313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 617.0
TLS2_k127_6784700_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 552.0
TLS2_k127_6784700_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 489.0
TLS2_k127_6784700_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K12420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 457.0
TLS2_k127_6784700_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 436.0
TLS2_k127_6784700_6 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 317.0
TLS2_k127_6784700_7 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 314.0
TLS2_k127_6784700_8 - - - - 0.000000000000000000000000000000000000000000003583 168.0
TLS2_k127_6784700_9 Could be a 3Fe-4S cluster-containing protein - - - 0.000000000000000000000000000000000000002605 162.0
TLS2_k127_6794488_0 TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 521.0
TLS2_k127_6794488_1 Binding-protein-dependent transport system inner membrane component K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 432.0
TLS2_k127_6794488_2 Binding-protein-dependent transport system inner membrane component K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 411.0
TLS2_k127_6794488_3 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 395.0
TLS2_k127_6794488_4 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000286 101.0
TLS2_k127_6794488_5 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000515 82.0
TLS2_k127_6794488_6 Nitrite and sulphite reductase 4Fe-4S - - - 0.0001088 45.0
TLS2_k127_6796496_0 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001299 265.0
TLS2_k127_6796496_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000301 273.0
TLS2_k127_6796496_2 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000001299 156.0
TLS2_k127_6800715_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 561.0
TLS2_k127_6800715_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 469.0
TLS2_k127_6800715_10 - - - - 0.0000000000000000000000000000000000002376 152.0
TLS2_k127_6800715_11 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000007653 50.0
TLS2_k127_6800715_12 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00001084 52.0
TLS2_k127_6800715_2 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 435.0
TLS2_k127_6800715_3 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 431.0
TLS2_k127_6800715_4 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 417.0
TLS2_k127_6800715_5 cytidyltransferase-related domain K00952 - 2.7.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006047 271.0
TLS2_k127_6800715_6 PFAM PHP domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000004178 250.0
TLS2_k127_6800715_7 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002057 250.0
TLS2_k127_6800715_9 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000000000009216 200.0
TLS2_k127_6802687_0 Iron-containing alcohol dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 576.0
TLS2_k127_6802687_1 Bacterial regulatory protein, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 497.0
TLS2_k127_6802687_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 478.0
TLS2_k127_6882885_0 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 525.0
TLS2_k127_6882885_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009649 271.0
TLS2_k127_6882885_2 Flavodoxin domain K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000001055 254.0
TLS2_k127_6882885_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000005648 238.0
TLS2_k127_6929108_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 5.679e-194 627.0
TLS2_k127_6929108_1 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 318.0
TLS2_k127_6929108_2 PHP domain protein - - - 0.0000000000000000000000000000000000000005579 168.0
TLS2_k127_6929108_3 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.000000000000000000000000000000000000001723 157.0
TLS2_k127_6929108_4 Type II and III secretion system protein K02453 - - 0.0000000000000000000421 95.0
TLS2_k127_6934686_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009099 257.0
TLS2_k127_6934686_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000001924 169.0
TLS2_k127_6934686_2 Heavy-metal resistance - - - 0.00000000000002021 86.0
TLS2_k127_6944214_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1542.0
TLS2_k127_6944214_1 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 297.0
TLS2_k127_6944214_2 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000112 277.0
TLS2_k127_6944214_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000001594 220.0
TLS2_k127_6944214_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000008761 177.0
TLS2_k127_6968353_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0 1066.0
TLS2_k127_6968353_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000001002 144.0
TLS2_k127_6968353_2 4Fe-4S dicluster domain K00196 - - 0.0000000000000000026 85.0
TLS2_k127_6998463_0 Histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 589.0
TLS2_k127_6998463_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 399.0
TLS2_k127_7000874_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 1.792e-220 718.0
TLS2_k127_7000874_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 387.0
TLS2_k127_7000874_2 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 335.0
TLS2_k127_7000874_4 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.0000000000000006394 84.0
TLS2_k127_700717_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 539.0
TLS2_k127_700717_1 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000000000000000006076 183.0
TLS2_k127_700717_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000005703 177.0
TLS2_k127_700717_3 Histidine kinase - - - 0.0000000000000000000004796 101.0
TLS2_k127_7020224_0 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 383.0
TLS2_k127_7020224_1 PFAM HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008751 250.0
TLS2_k127_7020224_2 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009024 239.0
TLS2_k127_7020224_3 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000000000000003624 190.0
TLS2_k127_7020224_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000000000000601 175.0
TLS2_k127_7020224_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000004409 154.0
TLS2_k127_7020224_6 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000000006892 145.0
TLS2_k127_7020224_7 PFAM RNA-binding S4 domain protein K14761 - - 0.000000000000001318 79.0
TLS2_k127_7020224_8 PFAM translation initiation factor SUI1 K03113 - - 0.00000000000007679 81.0
TLS2_k127_7042585_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.17e-202 640.0
TLS2_k127_7042585_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 565.0
TLS2_k127_7042585_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 563.0
TLS2_k127_7042585_3 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 386.0
TLS2_k127_7042585_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 380.0
TLS2_k127_7042585_5 Essential cell division protein K03589 - - 0.00000000000000000000000000000000000000000000000000000000000001979 222.0
TLS2_k127_7042585_6 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.0000000000000000000000000000000000000000000000000000000002117 204.0
TLS2_k127_7043139_0 Histidine kinase A domain protein - - - 7.982e-197 623.0
TLS2_k127_7043139_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 472.0
TLS2_k127_7043139_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000004781 174.0
TLS2_k127_7043139_3 TIGRFAM Tyrosine recombinase XerD K03733,K04763 - - 0.000000000000000000000000000000000000000005851 159.0
TLS2_k127_7049882_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 425.0
TLS2_k127_7052861_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.759e-211 661.0
TLS2_k127_7052861_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 610.0
TLS2_k127_7052861_2 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 531.0
TLS2_k127_7052861_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001844 285.0
TLS2_k127_7052861_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000002645 247.0
TLS2_k127_7052861_5 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000001446 192.0
TLS2_k127_7052861_6 Universal stress protein - - - 0.00000000000000000000000005671 112.0
TLS2_k127_7055101_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.752e-255 800.0
TLS2_k127_7055101_1 PFAM isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.161e-230 721.0
TLS2_k127_7055101_2 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000002628 204.0
TLS2_k127_7055101_3 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000001593 145.0
TLS2_k127_7055101_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000001109 94.0
TLS2_k127_7075868_0 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 1.494e-278 869.0
TLS2_k127_7075868_1 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 298.0
TLS2_k127_7081506_0 Histidine kinase K07644 - 2.7.13.3 3.783e-210 679.0
TLS2_k127_7081506_1 radical SAM domain protein K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 494.0
TLS2_k127_7081506_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 452.0
TLS2_k127_7081506_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 407.0
TLS2_k127_7081506_4 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 371.0
TLS2_k127_7082766_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 518.0
TLS2_k127_7082766_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 523.0
TLS2_k127_7082766_2 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003 275.0
TLS2_k127_7082766_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000003619 238.0
TLS2_k127_7082766_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000001103 156.0
TLS2_k127_7100137_0 PFAM ferredoxin-dependent glutamate synthase - - - 4.676e-286 886.0
TLS2_k127_7100137_1 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 295.0
TLS2_k127_7100137_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000002144 203.0
TLS2_k127_7100137_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000003601 206.0
TLS2_k127_7100137_4 histidine kinase dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000002606 171.0
TLS2_k127_7107094_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 402.0
TLS2_k127_7107094_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934,K13541,K21479 - 2.1.1.131,2.1.1.272,3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 376.0
TLS2_k127_7107094_2 PFAM cobalamin (vitamin B12) biosynthesis CbiG K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 371.0
TLS2_k127_7107094_3 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000001488 218.0
TLS2_k127_7107094_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000002343 188.0
TLS2_k127_7107094_5 ACT domain K07166 - - 0.0000000000000000000000000000000002203 138.0
TLS2_k127_7107094_6 VanZ like family - - - 0.00009302 55.0
TLS2_k127_7107845_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1362.0
TLS2_k127_7107845_1 NUDIX domain - - - 0.000000000000000000000000006934 110.0
TLS2_k127_7112050_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 4.347e-217 679.0
TLS2_k127_7112050_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007749 283.0
TLS2_k127_7112050_2 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000004052 233.0
TLS2_k127_7120827_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.255e-278 870.0
TLS2_k127_7120827_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 509.0
TLS2_k127_7120827_3 Pfam:Methyltransf_6 K10218 - 4.1.3.17 0.000000000000000000000000000000000000000000004424 174.0
TLS2_k127_7120827_4 PilZ domain K02676 - - 0.0004911 52.0
TLS2_k127_713119_0 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 7.161e-294 906.0
TLS2_k127_713119_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 424.0
TLS2_k127_713119_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 349.0
TLS2_k127_713119_3 Involved in chromosome partitioning - - - 0.000000000000000000000000000000000000000000000000000000005205 212.0
TLS2_k127_713119_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000004629 217.0
TLS2_k127_713119_5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000004521 199.0
TLS2_k127_713119_6 PFAM thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000000000001891 168.0
TLS2_k127_713119_7 - - - - 0.000002436 52.0
TLS2_k127_7141709_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 589.0
TLS2_k127_7141709_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 499.0
TLS2_k127_7141709_10 Nitroreductase family - - - 0.00000000001688 68.0
TLS2_k127_7141709_11 - - - - 0.0000000002482 68.0
TLS2_k127_7141709_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 475.0
TLS2_k127_7141709_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 387.0
TLS2_k127_7141709_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 289.0
TLS2_k127_7141709_5 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000009013 244.0
TLS2_k127_7141709_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000000003335 217.0
TLS2_k127_7141709_7 - - - - 0.0000000000000000000000000000000000001719 143.0
TLS2_k127_7141709_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000001771 124.0
TLS2_k127_7149079_0 AsmA-like C-terminal region K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 607.0
TLS2_k127_7149079_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000000000000000002492 161.0
TLS2_k127_7149079_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000001234 134.0
TLS2_k127_7149079_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000002191 54.0
TLS2_k127_7177866_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 532.0
TLS2_k127_7177866_1 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 354.0
TLS2_k127_7177866_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002756 275.0
TLS2_k127_7177866_3 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000025 231.0
TLS2_k127_7185616_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 3.359e-236 749.0
TLS2_k127_7185616_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 578.0
TLS2_k127_7185616_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 327.0
TLS2_k127_7185616_3 - - - - 0.000000000000000000000000000000000000000000000000000000002577 206.0
TLS2_k127_7185616_4 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000001847 135.0
TLS2_k127_7185616_5 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.00000000000000000000000008977 111.0
TLS2_k127_7207942_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004155 259.0
TLS2_k127_7207942_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000261 239.0
TLS2_k127_7207942_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000974 207.0
TLS2_k127_7207942_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000008912 113.0
TLS2_k127_7207942_4 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000000000000000765 108.0
TLS2_k127_7207942_5 PFAM response regulator receiver - - - 0.000000000000000000008822 97.0
TLS2_k127_7209699_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 372.0
TLS2_k127_7209699_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001892 287.0
TLS2_k127_721484_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 7.175e-225 706.0
TLS2_k127_721484_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 378.0
TLS2_k127_721484_10 - - - - 0.000000001123 61.0
TLS2_k127_721484_2 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 366.0
TLS2_k127_721484_3 Prokaryotic cytochrome b561 K08354 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 293.0
TLS2_k127_721484_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003205 279.0
TLS2_k127_721484_5 RNA binding S1 domain protein K06959 - - 0.0000000000000000000000000000000000000000000000000000000000000000007364 232.0
TLS2_k127_721484_6 - - - - 0.000000000000000000000000000000002469 136.0
TLS2_k127_721484_7 cheY-homologous receiver domain - - - 0.0000000000000000000000000000001476 132.0
TLS2_k127_721484_8 - - - - 0.0000000000000000001208 97.0
TLS2_k127_7215623_0 asparagine synthase (Glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 457.0
TLS2_k127_7215623_1 carbohydrate transport K02027,K10236 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 438.0
TLS2_k127_7215623_2 Carbohydrate ABC transporter ATP-binding protein, CUT1 family K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 369.0
TLS2_k127_7215623_3 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 351.0
TLS2_k127_7215623_4 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 322.0
TLS2_k127_7215623_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000008064 137.0
TLS2_k127_7215623_6 Carbon-nitrogen hydrolase - - - 0.000000000000000000001645 108.0
TLS2_k127_7215623_7 PepSY domain protein - - - 0.000000000001625 69.0
TLS2_k127_724702_0 DNA polymerase type-B family K02336 - 2.7.7.7 0.0 1007.0
TLS2_k127_7252525_0 PFAM Glutamine synthetase, catalytic K01915 - 6.3.1.2 4.48e-277 859.0
TLS2_k127_7252525_1 UPF0210 protein K09157 - - 7.074e-231 722.0
TLS2_k127_7252525_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 496.0
TLS2_k127_7252525_3 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 468.0
TLS2_k127_7271200_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.566e-292 930.0
TLS2_k127_7271200_1 PFAM Glycoside hydrolase 15-related - - - 5.126e-247 779.0
TLS2_k127_7271200_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 499.0
TLS2_k127_7271200_3 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007968 326.0
TLS2_k127_7271200_4 - - - - 0.000001907 53.0
TLS2_k127_7287129_0 PFAM glycosyl transferase family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 388.0
TLS2_k127_7287129_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001399 261.0
TLS2_k127_7287129_2 Met-10+ like-protein - - - 0.0000000000000000000000006143 117.0
TLS2_k127_731197_0 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 497.0
TLS2_k127_731197_1 Histidine kinase K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 463.0
TLS2_k127_731197_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 334.0
TLS2_k127_731197_3 Conserved protein K01163 - - 0.0000000000000000000000000000000000000000000000000000000000001406 229.0
TLS2_k127_731197_4 ATPase involved in DNA repair K03546 - - 0.0000000000000000000000000000000000000000000000000000001132 214.0
TLS2_k127_731197_5 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000001834 193.0
TLS2_k127_731197_6 - - - - 0.0000000000000000000000000000000000000000000002946 181.0
TLS2_k127_731197_7 Histidine kinase K02660,K11525 - - 0.0000000000000000000000000000004443 135.0
TLS2_k127_731197_8 Tetratricopeptide repeat - - - 0.00000000000000000001768 106.0
TLS2_k127_7333549_0 NapC/NirT cytochrome c family, N-terminal region - - - 2.753e-317 987.0
TLS2_k127_7333549_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 562.0
TLS2_k127_7333549_2 Protein of unknown function (DUF1186) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 392.0
TLS2_k127_7333549_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004252 252.0
TLS2_k127_7333549_4 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000001024 210.0
TLS2_k127_7333549_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000003991 151.0
TLS2_k127_7333549_6 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000003807 107.0
TLS2_k127_7333769_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1094.0
TLS2_k127_7333769_1 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 6.082e-207 652.0
TLS2_k127_7333769_2 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.172e-202 656.0
TLS2_k127_7333769_3 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 542.0
TLS2_k127_7333769_4 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 347.0
TLS2_k127_7333769_5 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000001984 119.0
TLS2_k127_7333769_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000003989 93.0
TLS2_k127_7341960_0 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 585.0
TLS2_k127_7341960_1 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000004288 180.0
TLS2_k127_7341960_2 SMART AAA ATPase K02450 - - 0.000005792 49.0
TLS2_k127_7360975_0 Threonine synthase K01733 - 4.2.3.1 1.116e-241 755.0
TLS2_k127_7368998_0 conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 594.0
TLS2_k127_7368998_1 PFAM methyltransferase K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000000000000000000004821 278.0
TLS2_k127_7368998_2 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000000000000000008566 149.0
TLS2_k127_737721_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1279.0
TLS2_k127_737721_1 Major Facilitator Superfamily K02445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 459.0
TLS2_k127_737721_2 mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 343.0
TLS2_k127_737721_3 PFAM Class II Aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 291.0
TLS2_k127_737721_4 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000002284 123.0
TLS2_k127_737721_5 - - - - 0.0000000000000000007644 92.0
TLS2_k127_7418553_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 385.0
TLS2_k127_7418553_1 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 352.0
TLS2_k127_7418553_2 glycosyl transferase group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 302.0
TLS2_k127_7418553_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009492 279.0
TLS2_k127_7432138_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1191.0
TLS2_k127_7432138_1 TIGRFAM nitrate reductase, beta subunit K00371 - 1.7.5.1 4.052e-223 703.0
TLS2_k127_7432138_2 Major Facilitator Superfamily K02575 - - 1.809e-200 634.0
TLS2_k127_7432138_3 Major facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 308.0
TLS2_k127_7432138_4 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 305.0
TLS2_k127_7432138_5 PFAM Nitrate reductase delta subunit K00373 - - 0.000000000000000000000000000000000000000000001054 173.0
TLS2_k127_7446203_0 PFAM FAD linked oxidase domain protein K00004,K00102,K00104 GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.1.1.303,1.1.1.4,1.1.2.4,1.1.3.15 2.439e-219 702.0
TLS2_k127_7446203_1 ABC 3 transport family K09816,K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 431.0
TLS2_k127_7446203_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004702 263.0
TLS2_k127_7446203_3 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000001163 234.0
TLS2_k127_7446203_4 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K02074,K09817 - - 0.000000000000000000000000000000000000000000000000000000000000001287 220.0
TLS2_k127_7446203_5 PFAM Dynamin family - - - 0.000000000004038 72.0
TLS2_k127_765748_0 N-terminal domain of unknown function (DUF4140) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 362.0
TLS2_k127_765748_1 Glycine zipper - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004862 267.0
TLS2_k127_765748_2 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000725 260.0
TLS2_k127_765748_3 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000196 235.0
TLS2_k127_765748_4 CRS1_YhbY K07574 - - 0.000000000000000000001901 98.0
TLS2_k127_780635_0 Required for chromosome condensation and partitioning K03529 - - 2.819e-253 801.0
TLS2_k127_792494_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1150.0
TLS2_k127_792494_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 527.0
TLS2_k127_794800_0 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 391.0
TLS2_k127_794800_1 PFAM PfkB domain protein K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 330.0
TLS2_k127_794800_2 diguanylate cyclase - - - 0.0000000000000000000000000000006329 124.0
TLS2_k127_802120_0 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000006887 252.0
TLS2_k127_802120_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000008668 254.0
TLS2_k127_802120_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000002883 136.0
TLS2_k127_802795_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1294.0
TLS2_k127_802795_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 609.0
TLS2_k127_802795_2 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 345.0
TLS2_k127_802795_3 PFAM regulatory protein TetR K13770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003237 274.0
TLS2_k127_802795_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000003093 128.0
TLS2_k127_805395_0 surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 541.0
TLS2_k127_805395_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 551.0
TLS2_k127_805395_2 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000000000000002821 222.0
TLS2_k127_805395_3 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000001972 138.0
TLS2_k127_835958_0 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000004644 208.0
TLS2_k127_849036_0 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) K01484 - 3.5.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 479.0
TLS2_k127_849036_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 368.0
TLS2_k127_849036_3 deoxyhypusine monooxygenase activity K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 348.0
TLS2_k127_849036_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000004424 209.0
TLS2_k127_849036_5 Belongs to the Fur family K09825 - - 0.000000000000000000000000000000000000005061 149.0
TLS2_k127_849036_6 Domain of unknown function (DUF4442) - - - 0.0000000000000000000006325 100.0
TLS2_k127_851769_0 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 363.0
TLS2_k127_851769_1 PFAM permease YjgP YjgQ family protein K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 296.0
TLS2_k127_851769_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000003238 147.0
TLS2_k127_901423_0 translation release factor activity K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 400.0
TLS2_k127_901423_1 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 334.0
TLS2_k127_906360_0 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 518.0
TLS2_k127_906360_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 352.0
TLS2_k127_906360_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 321.0
TLS2_k127_906360_3 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005511 280.0
TLS2_k127_906360_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004474 258.0
TLS2_k127_906360_5 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000006851 226.0
TLS2_k127_906360_6 Cytochrome c K08738 - - 0.0000000000000004847 85.0
TLS2_k127_906885_0 ABC transporter K06158 - - 1.443e-234 739.0
TLS2_k127_906885_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 5.076e-224 700.0
TLS2_k127_906885_2 Predicted membrane protein (DUF2232) - - - 0.0000000000000000000000000000000000000000000000000000000000000434 224.0
TLS2_k127_906885_3 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007966 209.0
TLS2_k127_906885_4 protein secretion K03116 - - 0.00000000000000000000000008798 109.0
TLS2_k127_909086_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 6.388e-268 833.0
TLS2_k127_909086_1 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 378.0
TLS2_k127_909086_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 304.0
TLS2_k127_968833_0 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 507.0
TLS2_k127_968833_1 Penicillin-binding protein 1A K05366,K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 354.0
TLS2_k127_968833_2 Psort location Cytoplasmic, score - - - 0.0003502 49.0
TLS2_k127_994658_0 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 503.0
TLS2_k127_994658_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 385.0
TLS2_k127_994658_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 349.0
TLS2_k127_994658_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000326 74.0
TLS2_k127_996555_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1356.0
TLS2_k127_996555_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 374.0
TLS2_k127_996555_2 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001075 245.0
TLS2_k127_996555_3 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000001333 230.0
TLS2_k127_996555_5 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000001268 134.0
TLS2_k127_996555_6 HDOD domain - - - 0.000000000000000001321 89.0
TLS2_k127_997154_0 Serine aminopeptidase, S33 K03928 - 3.1.1.1 5.915e-237 759.0
TLS2_k127_997154_1 PFAM homoserine dehydrogenase K00003 - 1.1.1.3 1.314e-206 653.0
TLS2_k127_997154_2 PFAM 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 565.0
TLS2_k127_997154_3 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000001862 167.0
TLS2_k127_997154_4 17 kDa outer membrane surface antigen - - - 0.00000000000000000000000000000000000005187 152.0
TLS2_k127_997154_5 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000002215 139.0