logo

Overview

ID MAG03993
Name TLS2_bin.26
Sample SMP0104
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Polyangia
Order Haliangiales
Family Haliangiaceae
Genus Haliangium
Species
Assembly information
Completeness (%) 89.01
Contamination (%) 1.49
GC content (%) 70.0
N50 (bp) 63,444
Genome size (bp) 7,917,599

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes5140

Gene name Description KEGG GOs EC E-value Score Sequence
TLS2_k127_1013203_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1188.0
TLS2_k127_1013203_1 Histidine kinase K02482,K07709,K10125 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010288,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071284,GO:0071294,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 1.199e-235 745.0
TLS2_k127_1013203_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 392.0
TLS2_k127_1013203_11 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 397.0
TLS2_k127_1013203_12 alcohol dehydrogenase K11337 - 1.1.1.396 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 340.0
TLS2_k127_1013203_13 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 324.0
TLS2_k127_1013203_14 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 314.0
TLS2_k127_1013203_15 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 292.0
TLS2_k127_1013203_16 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000003393 264.0
TLS2_k127_1013203_17 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000004318 261.0
TLS2_k127_1013203_18 Histidine kinase K01768,K03406,K11617 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000005929 254.0
TLS2_k127_1013203_19 Phage shock protein A K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000001382 239.0
TLS2_k127_1013203_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 2.031e-232 757.0
TLS2_k127_1013203_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06991 - - 0.0000000000000000000000000000000000000000000000000000000000005945 213.0
TLS2_k127_1013203_21 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000003088 213.0
TLS2_k127_1013203_22 Fumarate reductase, iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000006148 197.0
TLS2_k127_1013203_23 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000008273 192.0
TLS2_k127_1013203_24 sequence-specific DNA binding K07729 - - 0.00000000000000000000000000000000000000000000002013 174.0
TLS2_k127_1013203_25 Bifunctional nuclease K08999 - - 0.000000000000000000000000000002645 131.0
TLS2_k127_1013203_26 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.000000000000000000000000000004768 132.0
TLS2_k127_1013203_3 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 3.041e-232 726.0
TLS2_k127_1013203_30 - - - - 0.000000000004604 74.0
TLS2_k127_1013203_31 membrane K03497,K03628 - - 0.00000001919 66.0
TLS2_k127_1013203_4 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 600.0
TLS2_k127_1013203_5 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 586.0
TLS2_k127_1013203_6 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 485.0
TLS2_k127_1013203_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 490.0
TLS2_k127_1013203_8 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 478.0
TLS2_k127_1013203_9 maltose binding K10108,K10117,K15770 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 414.0
TLS2_k127_1037321_0 Histidine kinase - - - 0.0 3317.0
TLS2_k127_1037321_1 lipopolysaccharide metabolic process K19804 - - 0.0 1781.0
TLS2_k127_1037321_10 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000000000000000000000000008449 204.0
TLS2_k127_1037321_11 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000002677 192.0
TLS2_k127_1037321_12 AAA domain - - - 0.000000000000000000000000000000000000000000000009056 180.0
TLS2_k127_1037321_13 thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.0000000000000000000000000000000000000003674 162.0
TLS2_k127_1037321_15 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.0000000000000000000000000000000002469 134.0
TLS2_k127_1037321_17 Chorismate mutase type II K04782 - 4.2.99.21 0.00000000000000000746 95.0
TLS2_k127_1037321_19 - - - - 0.0001065 50.0
TLS2_k127_1037321_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 999.0
TLS2_k127_1037321_3 glutamine amidotransferase of anthranilate synthase K13950 - 2.6.1.85 5.959e-243 784.0
TLS2_k127_1037321_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 537.0
TLS2_k127_1037321_5 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 468.0
TLS2_k127_1037321_6 phosphorelay sensor kinase activity K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 464.0
TLS2_k127_1037321_7 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 406.0
TLS2_k127_1037321_8 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 387.0
TLS2_k127_1037321_9 Thg1 C terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 341.0
TLS2_k127_1056579_0 SNF2 family N-terminal domain - - - 6.052e-228 736.0
TLS2_k127_1056579_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 620.0
TLS2_k127_1056579_2 SWIM zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 314.0
TLS2_k127_1056579_3 - - - - 0.0000000000000000000000000000000000000000000000000000007549 200.0
TLS2_k127_1056579_4 Helicase - - - 0.00000000000000000000000000007962 127.0
TLS2_k127_1056579_5 Belongs to the ompA family K03640 - - 0.00000000000000000001758 104.0
TLS2_k127_1056579_7 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000001565 80.0
TLS2_k127_1062792_0 synthase K12436 - - 0.0 1376.0
TLS2_k127_1062792_1 Histidine kinase A domain protein - - - 0.0 1093.0
TLS2_k127_1062792_10 polyketide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009287 369.0
TLS2_k127_1062792_11 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 363.0
TLS2_k127_1062792_12 Transcription factor zinc-finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 322.0
TLS2_k127_1062792_13 CotH kinase protein K06330 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 316.0
TLS2_k127_1062792_14 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000271 229.0
TLS2_k127_1062792_15 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000007435 216.0
TLS2_k127_1062792_16 Domain of unknown function (DUF4157) K21472 - - 0.000000000000000000000000000000000000000000000000008633 203.0
TLS2_k127_1062792_17 Domain of unknown function (DUF4360) - - - 0.0000000000000000000000002687 114.0
TLS2_k127_1062792_18 signal sequence binding - - - 0.00000000000000000002113 100.0
TLS2_k127_1062792_2 - - - - 1.168e-245 795.0
TLS2_k127_1062792_20 Curli production assembly/transport component CsgG - - - 0.00000000000000006584 96.0
TLS2_k127_1062792_23 Peptidoglycan-binding domain 1 protein - - - 0.00000000000001277 88.0
TLS2_k127_1062792_3 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 618.0
TLS2_k127_1062792_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 442.0
TLS2_k127_1062792_5 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 447.0
TLS2_k127_1062792_6 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 430.0
TLS2_k127_1062792_7 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 399.0
TLS2_k127_1062792_8 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 399.0
TLS2_k127_1062792_9 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 361.0
TLS2_k127_1148567_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.489e-290 901.0
TLS2_k127_1148567_1 Belongs to the peptidase S8 family K14645 - - 9.325e-267 836.0
TLS2_k127_1148567_10 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 310.0
TLS2_k127_1148567_12 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000121 240.0
TLS2_k127_1148567_13 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000004294 232.0
TLS2_k127_1148567_14 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000009523 204.0
TLS2_k127_1148567_15 - - - - 0.00000000000000000000000000000000006625 145.0
TLS2_k127_1148567_2 Protein kinase domain K12132 - 2.7.11.1 1.859e-261 823.0
TLS2_k127_1148567_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 8.165e-261 808.0
TLS2_k127_1148567_4 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 5.577e-253 814.0
TLS2_k127_1148567_5 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 501.0
TLS2_k127_1148567_6 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 478.0
TLS2_k127_1148567_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 478.0
TLS2_k127_1148567_8 Bacterial regulatory protein, Fis family K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 427.0
TLS2_k127_1148567_9 carboxypeptidase K14054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 329.0
TLS2_k127_1153021_0 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 6.035e-254 798.0
TLS2_k127_1153021_1 UPF0313 protein - - - 1.931e-225 720.0
TLS2_k127_1153021_10 glycogen (starch) synthase activity K00693,K00696,K00754,K20430,K20444 - 2.4.1.11,2.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 380.0
TLS2_k127_1153021_11 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 370.0
TLS2_k127_1153021_12 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 357.0
TLS2_k127_1153021_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003673 286.0
TLS2_k127_1153021_14 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
TLS2_k127_1153021_15 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003019 266.0
TLS2_k127_1153021_16 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002788 273.0
TLS2_k127_1153021_18 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000000000000193 218.0
TLS2_k127_1153021_19 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000000000003836 184.0
TLS2_k127_1153021_2 Protein of unknown function, DUF255 K06888 - - 1.052e-196 641.0
TLS2_k127_1153021_21 ubiquinone biosynthetic process - - - 0.000000000000000000000000000000000000000000003921 175.0
TLS2_k127_1153021_23 Capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000005626 165.0
TLS2_k127_1153021_24 tRNA cytidylyltransferase activity - - - 0.00000000000000000000000000003967 127.0
TLS2_k127_1153021_25 protein conserved in bacteria - - - 0.0000000000000000000000000503 112.0
TLS2_k127_1153021_28 CpXC protein - - - 0.0000000000008056 81.0
TLS2_k127_1153021_3 Uncharacterized protein conserved in bacteria (DUF2330) - - - 2.128e-196 630.0
TLS2_k127_1153021_4 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 560.0
TLS2_k127_1153021_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 548.0
TLS2_k127_1153021_6 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 524.0
TLS2_k127_1153021_7 stress-induced mitochondrial fusion K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 514.0
TLS2_k127_1153021_8 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 448.0
TLS2_k127_1153021_9 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 379.0
TLS2_k127_1153052_0 - - - - 3e-323 1022.0
TLS2_k127_1153052_1 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008325 273.0
TLS2_k127_1153052_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001963 262.0
TLS2_k127_1153052_3 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000008136 209.0
TLS2_k127_1153052_4 COG3209 Rhs family protein - - - 0.000000000000000000000000002006 117.0
TLS2_k127_1153052_5 - - - - 0.0000000000000001468 85.0
TLS2_k127_1153052_6 self proteolysis - - - 0.00000000001054 78.0
TLS2_k127_1153052_7 non-ribosomal peptide synthetase - - - 0.00000009573 56.0
TLS2_k127_1153052_8 FHA domain containing protein - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00006871 57.0
TLS2_k127_1153357_0 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000005533 131.0
TLS2_k127_1153357_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000005106 98.0
TLS2_k127_1153357_2 Domain of unknown function (DUF2019) - - - 0.000000000001678 72.0
TLS2_k127_1170481_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1250.0
TLS2_k127_1170481_1 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1208.0
TLS2_k127_1170481_10 Belongs to the thiolase family K00632 - 2.3.1.16 1.685e-197 621.0
TLS2_k127_1170481_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 612.0
TLS2_k127_1170481_12 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 603.0
TLS2_k127_1170481_13 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 553.0
TLS2_k127_1170481_14 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 551.0
TLS2_k127_1170481_15 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 544.0
TLS2_k127_1170481_16 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 499.0
TLS2_k127_1170481_17 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 410.0
TLS2_k127_1170481_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 407.0
TLS2_k127_1170481_19 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 420.0
TLS2_k127_1170481_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1080.0
TLS2_k127_1170481_20 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 402.0
TLS2_k127_1170481_21 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 376.0
TLS2_k127_1170481_22 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 327.0
TLS2_k127_1170481_23 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 327.0
TLS2_k127_1170481_24 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 321.0
TLS2_k127_1170481_25 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 317.0
TLS2_k127_1170481_26 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 329.0
TLS2_k127_1170481_27 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 315.0
TLS2_k127_1170481_28 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 310.0
TLS2_k127_1170481_29 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 309.0
TLS2_k127_1170481_3 SMART helicase c2 K03722 - 3.6.4.12 1.252e-277 874.0
TLS2_k127_1170481_30 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 303.0
TLS2_k127_1170481_31 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001387 289.0
TLS2_k127_1170481_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007001 252.0
TLS2_k127_1170481_33 metallopeptidase activity K01081,K01183,K20276 - 3.1.3.5,3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000003623 265.0
TLS2_k127_1170481_34 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002046 226.0
TLS2_k127_1170481_36 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000001089 230.0
TLS2_k127_1170481_37 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001336 242.0
TLS2_k127_1170481_39 R3H domain K06346 - - 0.0000000000000000000000000000000000000000000000000000000000005629 219.0
TLS2_k127_1170481_4 Selenocysteine-specific translation elongation factor K03833 - - 5.908e-267 846.0
TLS2_k127_1170481_40 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000008107 212.0
TLS2_k127_1170481_41 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000021 195.0
TLS2_k127_1170481_42 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000009352 168.0
TLS2_k127_1170481_43 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000944 119.0
TLS2_k127_1170481_44 - - - - 0.0000000000000000000000000002686 117.0
TLS2_k127_1170481_45 COG1533 DNA repair photolyase - - - 0.000000000000000000000001009 106.0
TLS2_k127_1170481_46 LysR substrate binding domain - - - 0.00000000000000004728 93.0
TLS2_k127_1170481_47 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000006648 85.0
TLS2_k127_1170481_48 TPR repeat - - - 0.00000000001599 78.0
TLS2_k127_1170481_49 ABC-2 family transporter protein K01992 - - 0.00000000006251 72.0
TLS2_k127_1170481_5 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 3.865e-243 758.0
TLS2_k127_1170481_50 Ribosomal protein L34 K02914 - - 0.0000000006005 64.0
TLS2_k127_1170481_52 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0001153 52.0
TLS2_k127_1170481_53 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0006203 52.0
TLS2_k127_1170481_6 ABC-type uncharacterized transport system - - - 6.869e-212 688.0
TLS2_k127_1170481_7 Heat shock 70 kDa protein - - - 2.208e-208 668.0
TLS2_k127_1170481_8 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 3.694e-208 656.0
TLS2_k127_1170481_9 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.026e-201 646.0
TLS2_k127_1186670_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 546.0
TLS2_k127_1186670_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 433.0
TLS2_k127_1186670_2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 412.0
TLS2_k127_1186670_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 346.0
TLS2_k127_1186670_4 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 328.0
TLS2_k127_1186670_5 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003877 265.0
TLS2_k127_1186670_6 PFAM transposase, IS4 - - - 0.0000000000001226 79.0
TLS2_k127_1186670_7 Phosphopantetheine attachment site - - - 0.00000000003344 76.0
TLS2_k127_1186670_8 NAD-dependent epimerase dehydratase - - - 0.000003368 61.0
TLS2_k127_1203722_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1585.0
TLS2_k127_1203722_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1495.0
TLS2_k127_1203722_10 sigma54 specific, transcriptional regulator, Fis family - - - 2.524e-246 768.0
TLS2_k127_1203722_100 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000002943 191.0
TLS2_k127_1203722_101 PelD GGDEF domain K21009 - - 0.0000000000000000000000000000000000000000000000005744 194.0
TLS2_k127_1203722_102 AntiSigma factor K03088 - - 0.0000000000000000000000000000000000000000000000006138 179.0
TLS2_k127_1203722_103 lyase activity K21010 - - 0.00000000000000000000000000000000000000000000009938 183.0
TLS2_k127_1203722_104 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000003564 166.0
TLS2_k127_1203722_105 phosphatase K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000255 171.0
TLS2_k127_1203722_106 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000427 160.0
TLS2_k127_1203722_108 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000005125 154.0
TLS2_k127_1203722_109 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000304 171.0
TLS2_k127_1203722_11 Sodium:solute symporter family K03307 - - 4.063e-242 758.0
TLS2_k127_1203722_114 response regulator - - - 0.000000000000000000000000000000009197 143.0
TLS2_k127_1203722_116 Ferric uptake regulator family K09825 - - 0.000000000000000000000000000000854 125.0
TLS2_k127_1203722_119 Tetratricopeptide repeat K21007 - - 0.00000000000000000000000000006194 137.0
TLS2_k127_1203722_12 TonB dependent receptor K02014 - - 2.967e-237 753.0
TLS2_k127_1203722_126 carboxylic ester hydrolase activity - - - 0.000000000000000000001952 104.0
TLS2_k127_1203722_127 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03117 - - 0.00000000000000000000489 105.0
TLS2_k127_1203722_128 PFAM PEGA domain - - - 0.0000000000000000000251 105.0
TLS2_k127_1203722_129 S-acyltransferase activity K02487,K06596,K07576 - - 0.00000000000000000005398 104.0
TLS2_k127_1203722_13 synthase homocitrate synthase family K01649 - 2.3.3.13 8.017e-235 731.0
TLS2_k127_1203722_135 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000324 68.0
TLS2_k127_1203722_137 TPR repeat - - - 0.00001501 57.0
TLS2_k127_1203722_139 phospholipase K01127 GO:0001501,GO:0001503,GO:0001525,GO:0001568,GO:0001667,GO:0001944,GO:0002040,GO:0002042,GO:0002062,GO:0002253,GO:0002376,GO:0002429,GO:0002430,GO:0002682,GO:0002684,GO:0002757,GO:0002764,GO:0002768,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004620,GO:0004621,GO:0004630,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006109,GO:0006464,GO:0006497,GO:0006501,GO:0006505,GO:0006507,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006928,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0008081,GO:0008150,GO:0008152,GO:0008285,GO:0008286,GO:0009058,GO:0009059,GO:0009268,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009896,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010039,GO:0010040,GO:0010243,GO:0010562,GO:0010594,GO:0010595,GO:0010604,GO:0010631,GO:0010632,GO:0010634,GO:0010646,GO:0010647,GO:0010675,GO:0010676,GO:0010692,GO:0010694,GO:0010817,GO:0010866,GO:0010867,GO:0010896,GO:0010897,GO:0010906,GO:0010907,GO:0010921,GO:0010922,GO:0010941,GO:0010942,GO:0010982,GO:0010983,GO:0010984,GO:0010986,GO:0014070,GO:0016247,GO:0016298,GO:0016477,GO:0016787,GO:0016788,GO:0017080,GO:0018410,GO:0019216,GO:0019220,GO:0019222,GO:0019538,GO:0019637,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030162,GO:0030334,GO:0030335,GO:0031012,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031331,GO:0032024,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0033993,GO:0034014,GO:0034284,GO:0034645,GO:0035239,GO:0035295,GO:0035303,GO:0035306,GO:0035690,GO:0035701,GO:0035774,GO:0036211,GO:0036314,GO:0036315,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042157,GO:0042158,GO:0042176,GO:0042221,GO:0042268,GO:0042493,GO:0042578,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043434,GO:0043534,GO:0043542,GO:0043687,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044421,GO:0044424,GO:0044464,GO:0045732,GO:0045833,GO:0045834,GO:0045862,GO:0045913,GO:0045919,GO:0045937,GO:0046470,GO:0046486,GO:0046488,GO:0046883,GO:0046887,GO:0046889,GO:0046890,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050708,GO:0050714,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050796,GO:0050896,GO:0050994,GO:0050995,GO:0051043,GO:0051044,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051270,GO:0051272,GO:0051336,GO:0051345,GO:0051592,GO:0051674,GO:0051716,GO:0060255,GO:0060341,GO:0061178,GO:0061448,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070633,GO:0070723,GO:0070887,GO:0071214,GO:0071241,GO:0071248,GO:0071277,GO:0071281,GO:0071282,GO:0071310,GO:0071375,GO:0071396,GO:0071397,GO:0071401,GO:0071407,GO:0071417,GO:0071467,GO:0071495,GO:0071704,GO:0072358,GO:0072359,GO:0080090,GO:0090087,GO:0090130,GO:0090132,GO:0090207,GO:0090208,GO:0090209,GO:0090276,GO:0090277,GO:0097164,GO:0097241,GO:0097305,GO:0097306,GO:0098772,GO:0104004,GO:1900076,GO:1901135,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1903509,GO:1903530,GO:1903532,GO:1904951,GO:2000145,GO:2000147 3.1.4.50 0.0002075 55.0
TLS2_k127_1203722_14 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 1.023e-222 713.0
TLS2_k127_1203722_15 von Willebrand factor (vWF) type A domain - - - 2.19e-219 710.0
TLS2_k127_1203722_16 Predicted permease K07089 - - 6.794e-219 725.0
TLS2_k127_1203722_17 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 1.054e-211 669.0
TLS2_k127_1203722_18 Histidine kinase - - - 1.836e-211 668.0
TLS2_k127_1203722_19 Thiolase, C-terminal domain K00626,K07823 - 2.3.1.174,2.3.1.9 3.89e-205 643.0
TLS2_k127_1203722_2 repeat protein - - - 0.0 1415.0
TLS2_k127_1203722_20 adenosine deaminase K01488 - 3.5.4.4 1.014e-201 635.0
TLS2_k127_1203722_21 Patatin-like phospholipase K07001 - - 2.112e-199 634.0
TLS2_k127_1203722_22 Bacterial regulatory protein, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 589.0
TLS2_k127_1203722_24 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 595.0
TLS2_k127_1203722_25 Chalcone and stilbene synthases, N-terminal domain K16872 - 2.3.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 571.0
TLS2_k127_1203722_26 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 579.0
TLS2_k127_1203722_27 Domain of unknown function (DUF3492) K20921,K21011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 594.0
TLS2_k127_1203722_28 WYL domain K13572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 548.0
TLS2_k127_1203722_29 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 537.0
TLS2_k127_1203722_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0 1364.0
TLS2_k127_1203722_30 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 557.0
TLS2_k127_1203722_31 WYL domain K13573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 536.0
TLS2_k127_1203722_32 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 550.0
TLS2_k127_1203722_33 NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 539.0
TLS2_k127_1203722_34 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 525.0
TLS2_k127_1203722_35 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 524.0
TLS2_k127_1203722_36 Belongs to the ABC transporter superfamily K02031,K12371,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 498.0
TLS2_k127_1203722_37 PFAM TM1410 hypothetical-related protein K21006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 535.0
TLS2_k127_1203722_38 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 494.0
TLS2_k127_1203722_39 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009793 505.0
TLS2_k127_1203722_4 DNA helicase K03654 - 3.6.4.12 2.135e-319 1021.0
TLS2_k127_1203722_40 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 493.0
TLS2_k127_1203722_41 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 488.0
TLS2_k127_1203722_42 RNA polymerase K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 482.0
TLS2_k127_1203722_43 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 486.0
TLS2_k127_1203722_44 amine oxidase K00276 - 1.4.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 470.0
TLS2_k127_1203722_45 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 487.0
TLS2_k127_1203722_46 serine-type endopeptidase activity K01346 - 3.4.21.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 478.0
TLS2_k127_1203722_47 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 484.0
TLS2_k127_1203722_48 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 427.0
TLS2_k127_1203722_49 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 434.0
TLS2_k127_1203722_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.118e-312 974.0
TLS2_k127_1203722_50 Putative exopolysaccharide Exporter (EPS-E) K21012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 444.0
TLS2_k127_1203722_51 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 396.0
TLS2_k127_1203722_52 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 390.0
TLS2_k127_1203722_53 LPPG Fo 2-phospho-L-lactate transferase K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 403.0
TLS2_k127_1203722_54 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 387.0
TLS2_k127_1203722_55 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 402.0
TLS2_k127_1203722_56 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 393.0
TLS2_k127_1203722_57 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 374.0
TLS2_k127_1203722_59 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 374.0
TLS2_k127_1203722_6 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.053e-307 961.0
TLS2_k127_1203722_60 Oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 380.0
TLS2_k127_1203722_61 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 383.0
TLS2_k127_1203722_62 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 368.0
TLS2_k127_1203722_63 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 347.0
TLS2_k127_1203722_64 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 358.0
TLS2_k127_1203722_65 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 358.0
TLS2_k127_1203722_66 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 333.0
TLS2_k127_1203722_67 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 328.0
TLS2_k127_1203722_68 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 328.0
TLS2_k127_1203722_69 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 322.0
TLS2_k127_1203722_7 Belongs to the ompA family - - - 8.749e-261 817.0
TLS2_k127_1203722_70 PilZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 319.0
TLS2_k127_1203722_71 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 316.0
TLS2_k127_1203722_72 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 342.0
TLS2_k127_1203722_73 synthetase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 327.0
TLS2_k127_1203722_74 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 327.0
TLS2_k127_1203722_75 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 305.0
TLS2_k127_1203722_76 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 305.0
TLS2_k127_1203722_77 ABC-type oligopeptide transport system periplasmic component K02035,K12368,K13893,K15580,K16199,K19226 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 323.0
TLS2_k127_1203722_78 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 297.0
TLS2_k127_1203722_79 F420-0:Gamma-glutamyl ligase K12234,K22099 - 6.3.2.12,6.3.2.17,6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 301.0
TLS2_k127_1203722_8 response regulator K07714 - - 1.528e-250 781.0
TLS2_k127_1203722_80 oligopeptide transport system permease protein OppB K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 295.0
TLS2_k127_1203722_81 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000148 287.0
TLS2_k127_1203722_82 proteolysis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002381 277.0
TLS2_k127_1203722_83 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000231 277.0
TLS2_k127_1203722_84 NADPH-dependent f420 reductase K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000004668 265.0
TLS2_k127_1203722_85 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000608 266.0
TLS2_k127_1203722_87 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001188 252.0
TLS2_k127_1203722_88 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006278 246.0
TLS2_k127_1203722_89 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000664 240.0
TLS2_k127_1203722_9 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 4.566e-247 777.0
TLS2_k127_1203722_90 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000009841 243.0
TLS2_k127_1203722_91 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000000000000001016 234.0
TLS2_k127_1203722_92 peptidase K21471 - - 0.0000000000000000000000000000000000000000000000000000000000001883 221.0
TLS2_k127_1203722_93 PFAM PHA accumulation regulator DNA-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000004621 237.0
TLS2_k127_1203722_94 DegT DnrJ EryC1 StrS aminotransferase K07806 - 2.6.1.87 0.00000000000000000000000000000000000000000000000000000000005937 218.0
TLS2_k127_1203722_96 Redoxin - - - 0.000000000000000000000000000000000000000000000000000002276 199.0
TLS2_k127_1203722_97 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000003139 199.0
TLS2_k127_1203722_98 Prolyl 4-hydroxylase alpha subunit homologues. K07394 - - 0.00000000000000000000000000000000000000000000000000006143 199.0
TLS2_k127_1203722_99 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000000000003151 194.0
TLS2_k127_1234937_0 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 4.4e-323 1005.0
TLS2_k127_1234937_1 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 1.808e-280 876.0
TLS2_k127_1234937_11 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000002611 151.0
TLS2_k127_1234937_12 Belongs to the ompA family - - - 0.000000000000000000002241 110.0
TLS2_k127_1234937_2 Domain of unknown function (DUF1929) K04618 - 1.1.3.9 8.148e-275 863.0
TLS2_k127_1234937_3 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 519.0
TLS2_k127_1234937_4 TIGRFAM cysteine-rich repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 402.0
TLS2_k127_1234937_5 Major royal jelly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 388.0
TLS2_k127_1234937_6 Belongs to the helicase family. UvrD subfamily K07465 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 373.0
TLS2_k127_1234937_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001185 253.0
TLS2_k127_1234937_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000007963 248.0
TLS2_k127_1234937_9 metallocarboxypeptidase activity K14054 - - 0.0000000000000000000000000000000000000334 155.0
TLS2_k127_1274632_0 Vault protein inter-alpha-trypsin domain K07114 - - 2.807e-317 991.0
TLS2_k127_1274632_1 Alpha amylase, catalytic domain - - - 1.782e-222 699.0
TLS2_k127_1274632_11 HEPN domain - - - 0.00000000003266 66.0
TLS2_k127_1274632_12 30S ribosomal protein S23 - - - 0.0000002418 56.0
TLS2_k127_1274632_2 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 428.0
TLS2_k127_1274632_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 352.0
TLS2_k127_1274632_4 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 336.0
TLS2_k127_1274632_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 341.0
TLS2_k127_1274632_6 diphthine-ammonia ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006915 251.0
TLS2_k127_1274632_7 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004315 242.0
TLS2_k127_1274632_8 bacterial-type flagellum organization K02411 - - 0.000000000000000000000000000000000000000000000000001694 195.0
TLS2_k127_1274632_9 - K01865 - 5.4.4.1 0.000000000000000000000000000000000000008534 150.0
TLS2_k127_1283508_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 496.0
TLS2_k127_1283508_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 372.0
TLS2_k127_1283508_2 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 341.0
TLS2_k127_1283508_4 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001769 240.0
TLS2_k127_1283508_5 membrane protein (homolog of Drosophila rhomboid) - - - 0.000000000000000000000000000000000000000000000000000009214 198.0
TLS2_k127_1283508_6 transcription factor binding K02482,K22010 - 2.7.13.3 0.000000000000000000000000000000000000000000003514 172.0
TLS2_k127_1283655_0 May be involved in recombinational repair of damaged DNA K03631 - - 1.009e-236 747.0
TLS2_k127_1283655_1 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 593.0
TLS2_k127_1283655_10 Pfam:DUF385 - - - 0.000000000000000005447 92.0
TLS2_k127_1283655_11 Belongs to the thioredoxin family K03671 - - 0.00003278 56.0
TLS2_k127_1283655_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 462.0
TLS2_k127_1283655_3 Predicted AAA-ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 437.0
TLS2_k127_1283655_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 407.0
TLS2_k127_1283655_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 388.0
TLS2_k127_1283655_6 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 353.0
TLS2_k127_1283655_7 deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000159 258.0
TLS2_k127_1283655_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000001738 241.0
TLS2_k127_1283655_9 phosphatase activity - - - 0.00000000000000000000000000000000002587 148.0
TLS2_k127_1343528_0 protein containing a von Willebrand factor type A (vWA) domain - - - 1.06e-234 736.0
TLS2_k127_1343528_1 - - - - 5.723e-226 716.0
TLS2_k127_1343528_10 Transposase K07483 - - 0.0000000000000001803 85.0
TLS2_k127_1343528_11 TIGRFAM RHS repeat-associated core domain-containing protein, YD repeat protein - - - 0.000000002262 70.0
TLS2_k127_1343528_2 AAA domain (dynein-related subfamily) K03924 - - 2.767e-212 664.0
TLS2_k127_1343528_3 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 605.0
TLS2_k127_1343528_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 483.0
TLS2_k127_1343528_5 HTH-like domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 357.0
TLS2_k127_1343528_6 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 302.0
TLS2_k127_1343528_7 response regulator - - - 0.00000000000000000000000000000000000006111 145.0
TLS2_k127_1343528_8 - - - - 0.00000000000000000000000000003864 120.0
TLS2_k127_1343528_9 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000099 85.0
TLS2_k127_1353912_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.421e-229 717.0
TLS2_k127_1353912_1 Histidine kinase K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 617.0
TLS2_k127_1353912_2 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 549.0
TLS2_k127_1353912_3 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 542.0
TLS2_k127_1353912_4 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 502.0
TLS2_k127_1353912_5 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 396.0
TLS2_k127_1353912_6 two-component system sensor protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 407.0
TLS2_k127_1353912_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.0006452 48.0
TLS2_k127_1401298_0 polyketide synthase K13614 - - 0.0 2152.0
TLS2_k127_1401298_1 PKS_KR - - - 0.0 1693.0
TLS2_k127_1401298_10 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 549.0
TLS2_k127_1401298_11 PFAM Squalene phytoene synthase K02291,K21678,K21679 - 2.5.1.103,2.5.1.32,2.5.1.99,4.2.3.156 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 525.0
TLS2_k127_1401298_12 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 464.0
TLS2_k127_1401298_13 ABC transporter K06147,K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 424.0
TLS2_k127_1401298_14 amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 319.0
TLS2_k127_1401298_15 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 317.0
TLS2_k127_1401298_16 Malonyl CoA-acyl carrier protein transacylase K15329 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 299.0
TLS2_k127_1401298_17 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000166 286.0
TLS2_k127_1401298_18 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000001734 265.0
TLS2_k127_1401298_19 GHMP kinases N terminal domain K00938 - 2.7.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000004646 271.0
TLS2_k127_1401298_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0 1176.0
TLS2_k127_1401298_20 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002098 236.0
TLS2_k127_1401298_21 Dioxygenases related to 2-nitropropane dioxygenase K15329 - - 0.0000000000000000000000000000000000000000000000000000000000135 228.0
TLS2_k127_1401298_22 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000001098 219.0
TLS2_k127_1401298_24 KR domain - - - 0.00000000000000000000000000000000000000000000000001955 189.0
TLS2_k127_1401298_25 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000003798 193.0
TLS2_k127_1401298_26 Protein of unknown function (DUF1679) - - - 0.0000000000000000000000000000000000000000000000002459 203.0
TLS2_k127_1401298_27 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000000000000004964 177.0
TLS2_k127_1401298_28 Short-chain dehydrogenase reductase SDR K00076 - 1.1.1.159 0.000000000000000000000000000000000000000000000528 176.0
TLS2_k127_1401298_29 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000001342 168.0
TLS2_k127_1401298_3 Rhs family - - - 0.0 1111.0
TLS2_k127_1401298_30 Arsenical resistance operon trans-acting repressor ArsD - - - 0.00000000000000000000000000000000000000000001672 167.0
TLS2_k127_1401298_31 OsmC-like protein - - - 0.00000000000000000000000000000000000000003215 159.0
TLS2_k127_1401298_33 Cytochrome c - - - 0.0000000000000000000000000000000000002699 160.0
TLS2_k127_1401298_35 Isochorismatase family - - - 0.000000000000000000000000000000000705 138.0
TLS2_k127_1401298_37 chloramphenicol K18554 - - 0.00000000000000000000000000001045 130.0
TLS2_k127_1401298_38 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000008354 116.0
TLS2_k127_1401298_39 mevalonate kinase K00869 - 2.7.1.36 0.00000000000000000000000001655 124.0
TLS2_k127_1401298_4 Domain of unknown function (DUF3416) K16147 - 2.4.99.16 1.042e-275 869.0
TLS2_k127_1401298_40 Streptomycin adenylyltransferase K05593 - - 0.00000000000000000000005173 115.0
TLS2_k127_1401298_41 SMART Cystathionine beta-synthase, core - - - 0.00000000000000000003994 102.0
TLS2_k127_1401298_42 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000003927 85.0
TLS2_k127_1401298_46 (FHA) domain - - - 0.0002221 53.0
TLS2_k127_1401298_5 AAA domain K01551 - 3.6.3.16 2.723e-240 762.0
TLS2_k127_1401298_6 Sigma-54 interaction domain - - - 1.765e-230 748.0
TLS2_k127_1401298_8 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 587.0
TLS2_k127_1401298_9 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 591.0
TLS2_k127_140533_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1338.0
TLS2_k127_140533_1 TonB dependent receptor - - - 0.0 1337.0
TLS2_k127_140533_10 antibiotic catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 636.0
TLS2_k127_140533_11 ABC transporter substrate-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 602.0
TLS2_k127_140533_12 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 531.0
TLS2_k127_140533_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 527.0
TLS2_k127_140533_14 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 524.0
TLS2_k127_140533_15 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 572.0
TLS2_k127_140533_16 thiamine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 526.0
TLS2_k127_140533_17 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 505.0
TLS2_k127_140533_18 defense response to virus K19134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 522.0
TLS2_k127_140533_19 Binding-protein-dependent transport system inner membrane component K02025,K05814,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 468.0
TLS2_k127_140533_2 SMART serine threonine protein kinase - - - 0.0 1199.0
TLS2_k127_140533_20 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 436.0
TLS2_k127_140533_21 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 421.0
TLS2_k127_140533_22 Binding-protein-dependent transport system inner membrane component K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 408.0
TLS2_k127_140533_23 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 387.0
TLS2_k127_140533_24 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 384.0
TLS2_k127_140533_25 crispr-associated protein K00970,K07016,K19076 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 371.0
TLS2_k127_140533_26 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 372.0
TLS2_k127_140533_27 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 351.0
TLS2_k127_140533_28 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 329.0
TLS2_k127_140533_29 defense response to virus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 344.0
TLS2_k127_140533_3 Collagenase K08303 - - 0.0 1152.0
TLS2_k127_140533_30 cell wall glycoprotein biosynthetic process K00344,K01809,K01840,K03431,K04035,K15778,K16881 GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.14.13.81,1.6.5.5,2.7.7.13,5.3.1.8,5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 336.0
TLS2_k127_140533_31 amino acid K16263 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 327.0
TLS2_k127_140533_32 TIGRFAM CRISPR-associated RAMP protein, SSO1426 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 321.0
TLS2_k127_140533_33 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 312.0
TLS2_k127_140533_34 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 314.0
TLS2_k127_140533_35 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 291.0
TLS2_k127_140533_36 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 296.0
TLS2_k127_140533_37 metal-dependent protease of the Pad1 Jab1 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002994 300.0
TLS2_k127_140533_38 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000245 275.0
TLS2_k127_140533_39 YqcI/YcgG family K09190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005187 260.0
TLS2_k127_140533_4 SMART serine threonine protein kinase - - - 0.0 1144.0
TLS2_k127_140533_40 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001183 256.0
TLS2_k127_140533_41 Domain of unknown function (DUF4202) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003651 251.0
TLS2_k127_140533_42 Domain of unknown function (DUF4037) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001318 246.0
TLS2_k127_140533_43 defense response to virus - - - 0.000000000000000000000000000000000000000000000000000000000000000000002309 260.0
TLS2_k127_140533_44 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000004147 228.0
TLS2_k127_140533_45 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000001891 218.0
TLS2_k127_140533_46 PFAM Annexin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000056 239.0
TLS2_k127_140533_47 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000003857 215.0
TLS2_k127_140533_48 metal-dependent membrane protease K07052 - - 0.000000000000000000000000000000000000000000000000002807 195.0
TLS2_k127_140533_49 Belongs to the ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000009284 182.0
TLS2_k127_140533_5 helicase domain protein - - - 2.522e-315 985.0
TLS2_k127_140533_50 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000000007908 199.0
TLS2_k127_140533_51 - - - - 0.00000000000000000000000000000000000000000000000168 188.0
TLS2_k127_140533_52 COG0784 FOG CheY-like receiver - - - 0.0000000000000000000000000000000000000000000000622 172.0
TLS2_k127_140533_53 FR47-like protein - - - 0.00000000000000000000000000000000000001523 151.0
TLS2_k127_140533_54 - - - - 0.0000000000000000000000000000001617 127.0
TLS2_k127_140533_59 Cupin domain - - - 0.000000000000000000007461 95.0
TLS2_k127_140533_6 Glycosyl hydrolase family 65, C-terminal domain - - - 7.872e-305 957.0
TLS2_k127_140533_60 bacterial-type flagellum organization K02411 - - 0.00000000000000000007853 93.0
TLS2_k127_140533_61 deoxyhypusine monooxygenase activity - - - 0.0000000000000000005901 99.0
TLS2_k127_140533_62 bacterial-type flagellum organization - - - 0.00000000000197 79.0
TLS2_k127_140533_63 CpXC protein - - - 0.000000000002297 78.0
TLS2_k127_140533_7 OmpA family - - - 3.701e-292 940.0
TLS2_k127_140533_8 Protein conserved in bacteria - - - 2.494e-227 713.0
TLS2_k127_140533_9 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 1.434e-214 677.0
TLS2_k127_1424519_0 peptidase U62 modulator of DNA gyrase - - - 2.296e-293 912.0
TLS2_k127_1424519_1 Malate synthase K01638 - 2.3.3.9 2.393e-256 799.0
TLS2_k127_1424519_10 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04068 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000007268 248.0
TLS2_k127_1424519_11 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000005537 192.0
TLS2_k127_1424519_12 Restriction endonuclease fold toxin 5 - - - 0.000000000000000000000000000000001567 134.0
TLS2_k127_1424519_2 peptidase U62 modulator of DNA gyrase - - - 3.571e-243 796.0
TLS2_k127_1424519_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 8.572e-240 768.0
TLS2_k127_1424519_4 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0071704 4.1.3.1 1.5e-214 673.0
TLS2_k127_1424519_5 ABC1 family - - - 7.236e-200 649.0
TLS2_k127_1424519_6 IrrE N-terminal-like domain K07110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 462.0
TLS2_k127_1424519_7 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 373.0
TLS2_k127_1424519_8 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 387.0
TLS2_k127_1424519_9 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K07679 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001682 258.0
TLS2_k127_1487988_0 Alpha-2-Macroglobulin K06894 - - 1.393e-291 963.0
TLS2_k127_1487988_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.844e-290 904.0
TLS2_k127_1487988_10 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 331.0
TLS2_k127_1487988_11 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 336.0
TLS2_k127_1487988_12 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 310.0
TLS2_k127_1487988_13 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007039 269.0
TLS2_k127_1487988_14 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001337 229.0
TLS2_k127_1487988_15 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000004038 186.0
TLS2_k127_1487988_16 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000001924 73.0
TLS2_k127_1487988_18 ribosome binding - - - 0.00008696 53.0
TLS2_k127_1487988_2 bacterial-type flagellum-dependent cell motility - - - 3.975e-252 798.0
TLS2_k127_1487988_3 SMART Integrin alpha beta-propellor repeat protein - - - 4.902e-218 697.0
TLS2_k127_1487988_4 Cytochrome c554 and c-prime - - - 2.085e-213 713.0
TLS2_k127_1487988_5 Insulinase (Peptidase family M16) K07263 - - 7.246e-206 668.0
TLS2_k127_1487988_6 Protein conserved in bacteria - - - 7.334e-194 620.0
TLS2_k127_1487988_7 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365,K05367 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 544.0
TLS2_k127_1487988_8 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 477.0
TLS2_k127_1487988_9 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 442.0
TLS2_k127_1598889_0 Male sterility protein K01897 - 6.2.1.3 0.0 2179.0
TLS2_k127_1598889_1 Domain of unknown function (DUF2088) - - - 0.0 1006.0
TLS2_k127_1598889_10 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 325.0
TLS2_k127_1598889_11 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 291.0
TLS2_k127_1598889_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001581 268.0
TLS2_k127_1598889_13 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000003049 228.0
TLS2_k127_1598889_14 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000001167 183.0
TLS2_k127_1598889_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000007146 184.0
TLS2_k127_1598889_17 - - - - 0.000000000000000000000000000000000000009931 158.0
TLS2_k127_1598889_18 GDP-mannose mannosyl hydrolase activity K01515 - 3.6.1.13 0.00000000000000000000000002432 115.0
TLS2_k127_1598889_19 Subtilase family K01179,K13276 GO:0005575,GO:0005576 3.2.1.4 0.0000000000000000000001576 107.0
TLS2_k127_1598889_2 dehydrogenase e1 component K00164 - 1.2.4.2 9.418e-288 912.0
TLS2_k127_1598889_20 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000112 108.0
TLS2_k127_1598889_21 Protein of unknown function (DUF1016) - - - 0.00000000000000000005439 93.0
TLS2_k127_1598889_23 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000002144 75.0
TLS2_k127_1598889_24 response regulator - - - 0.0001004 54.0
TLS2_k127_1598889_3 ABC transporter - - - 5.509e-268 844.0
TLS2_k127_1598889_4 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 510.0
TLS2_k127_1598889_5 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 463.0
TLS2_k127_1598889_6 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 450.0
TLS2_k127_1598889_7 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 404.0
TLS2_k127_1598889_8 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 351.0
TLS2_k127_1598889_9 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009615 353.0
TLS2_k127_16207_0 Efflux ABC transporter, permease ATP-binding protein K06147 - - 4.101e-273 854.0
TLS2_k127_16207_1 Tetratricopeptide repeats - - - 1.482e-272 868.0
TLS2_k127_16207_10 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 416.0
TLS2_k127_16207_11 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 349.0
TLS2_k127_16207_12 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 318.0
TLS2_k127_16207_13 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 325.0
TLS2_k127_16207_14 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003399 276.0
TLS2_k127_16207_15 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001108 279.0
TLS2_k127_16207_16 Putative transposase, YhgA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001641 275.0
TLS2_k127_16207_17 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000218 256.0
TLS2_k127_16207_18 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000167 237.0
TLS2_k127_16207_19 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000003946 214.0
TLS2_k127_16207_2 lysine 2,3-aminomutase K01843 - 5.4.3.2 4.159e-254 794.0
TLS2_k127_16207_21 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000000000000000000001585 200.0
TLS2_k127_16207_22 Putative transposase, YhgA-like - - - 0.0000000000000000000000000000000000000000000000000000001631 207.0
TLS2_k127_16207_23 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000004141 179.0
TLS2_k127_16207_24 spore germination K03605 - - 0.000000000000000000000000000462 131.0
TLS2_k127_16207_25 HupF/HypC family K04653 - - 0.0000000000000000000007317 98.0
TLS2_k127_16207_26 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000001332 98.0
TLS2_k127_16207_28 Cytochrome c, class I - - - 0.000000000006878 77.0
TLS2_k127_16207_3 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 1.409e-246 766.0
TLS2_k127_16207_4 4Fe-4S dicluster domain - - - 1.286e-224 719.0
TLS2_k127_16207_5 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 2.643e-213 686.0
TLS2_k127_16207_6 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 591.0
TLS2_k127_16207_7 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 529.0
TLS2_k127_16207_8 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 460.0
TLS2_k127_16207_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 419.0
TLS2_k127_164448_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 616.0
TLS2_k127_164448_1 Probably plays an important role in intracellular peptide degradation K07751 - 3.4.11.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 476.0
TLS2_k127_164448_2 Type I restriction enzyme R protein N terminus (HSDR_N) K07504 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002153 291.0
TLS2_k127_164448_3 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000009251 188.0
TLS2_k127_1752592_0 Histidine kinase A domain protein - - - 0.0 2609.0
TLS2_k127_1752592_1 von Willebrand factor type A domain - - - 0.0 1388.0
TLS2_k127_1752592_11 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 447.0
TLS2_k127_1752592_12 Somatomedin B domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 446.0
TLS2_k127_1752592_13 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 376.0
TLS2_k127_1752592_14 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 342.0
TLS2_k127_1752592_15 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 336.0
TLS2_k127_1752592_16 NADPH-dependent FMN reductase K00299,K11811 - 1.5.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002658 269.0
TLS2_k127_1752592_17 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001412 252.0
TLS2_k127_1752592_18 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008122 251.0
TLS2_k127_1752592_19 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000001405 230.0
TLS2_k127_1752592_2 Aerotolerance regulator N-terminal - - - 8.133e-275 864.0
TLS2_k127_1752592_20 PFAM TM2 domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000004201 221.0
TLS2_k127_1752592_21 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000007351 222.0
TLS2_k127_1752592_23 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.000000000000000000000000000000000001635 140.0
TLS2_k127_1752592_26 protein conserved in cyanobacteria - - - 0.0000000000000000000000005746 110.0
TLS2_k127_1752592_28 TM2 domain - - - 0.0000000001049 66.0
TLS2_k127_1752592_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.018e-227 726.0
TLS2_k127_1752592_4 serine threonine protein kinase K12132 - 2.7.11.1 2.03e-211 678.0
TLS2_k127_1752592_5 nuclear chromosome segregation - - - 2.132e-205 658.0
TLS2_k127_1752592_6 Histidine kinase A domain protein K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 546.0
TLS2_k127_1752592_7 Von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 525.0
TLS2_k127_1752592_8 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 555.0
TLS2_k127_1752592_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 469.0
TLS2_k127_1757346_0 Superfamily II DNA RNA helicases, SNF2 family - - - 0.0 1414.0
TLS2_k127_1757346_1 Esterase-like activity of phytase K01126 - 3.1.4.46 1.537e-320 1002.0
TLS2_k127_1757346_2 Bacterial extracellular solute-binding protein K17321 - - 1.136e-307 948.0
TLS2_k127_1757346_3 oxidoreductase activity K07114 - - 1.805e-220 698.0
TLS2_k127_1757346_4 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 562.0
TLS2_k127_1757346_5 Binding-protein-dependent transport system inner membrane component K17322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 503.0
TLS2_k127_1757346_6 Binding-protein-dependent transport system inner membrane component K02026,K17323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 464.0
TLS2_k127_1757346_7 TOBE domain K17325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 411.0
TLS2_k127_1757346_8 ABC transporter K17324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 367.0
TLS2_k127_1757346_9 Predicted small integral membrane protein (DUF2160) - - - 0.000000000000000000000000000005648 120.0
TLS2_k127_1845533_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1669.0
TLS2_k127_1845533_1 Cytochrome c-type biogenesis protein K02198 - - 0.0 1381.0
TLS2_k127_1845533_10 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 473.0
TLS2_k127_1845533_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 485.0
TLS2_k127_1845533_12 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 467.0
TLS2_k127_1845533_13 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 393.0
TLS2_k127_1845533_14 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 365.0
TLS2_k127_1845533_15 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 347.0
TLS2_k127_1845533_16 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 367.0
TLS2_k127_1845533_17 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 351.0
TLS2_k127_1845533_18 ChrR Cupin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 334.0
TLS2_k127_1845533_19 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 308.0
TLS2_k127_1845533_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.627e-318 1002.0
TLS2_k127_1845533_20 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 296.0
TLS2_k127_1845533_21 protein-(glutamine-N5) methyltransferase activity K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001538 305.0
TLS2_k127_1845533_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002559 263.0
TLS2_k127_1845533_23 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000006366 229.0
TLS2_k127_1845533_24 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000251 211.0
TLS2_k127_1845533_25 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000001894 194.0
TLS2_k127_1845533_27 - - - - 0.000000000000000000000000000000000000000004403 159.0
TLS2_k127_1845533_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.294e-221 691.0
TLS2_k127_1845533_33 UPF0391 membrane protein - - - 0.00000000008852 65.0
TLS2_k127_1845533_35 Domain of unknown function (DUF4157) - - - 0.0007178 45.0
TLS2_k127_1845533_4 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 4.41e-220 705.0
TLS2_k127_1845533_6 peptidyl-tyrosine sulfation - - - 4.699e-198 640.0
TLS2_k127_1845533_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 602.0
TLS2_k127_1845533_8 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 570.0
TLS2_k127_1845533_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 573.0
TLS2_k127_1882308_0 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000005566 143.0
TLS2_k127_1882308_1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH - - - 0.0000000000000000006802 102.0
TLS2_k127_1882308_2 - - - - 0.000000000000001222 91.0
TLS2_k127_192684_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1207.0
TLS2_k127_192684_1 serine threonine protein kinase K12132 - 2.7.11.1 1.387e-262 840.0
TLS2_k127_192684_10 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 458.0
TLS2_k127_192684_11 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 423.0
TLS2_k127_192684_12 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 369.0
TLS2_k127_192684_13 Metallo-beta-lactamase superfamily protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 331.0
TLS2_k127_192684_14 PFAM Diacylglycerol kinase, catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 299.0
TLS2_k127_192684_15 glutathione transferase activity K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000003826 239.0
TLS2_k127_192684_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009776 241.0
TLS2_k127_192684_17 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000001653 232.0
TLS2_k127_192684_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000002427 252.0
TLS2_k127_192684_19 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000638 205.0
TLS2_k127_192684_2 ABC transporter K02056,K05776,K10441,K10545,K10548 - 3.6.3.17 1.947e-245 769.0
TLS2_k127_192684_21 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000003309 190.0
TLS2_k127_192684_22 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000003527 177.0
TLS2_k127_192684_23 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000003758 164.0
TLS2_k127_192684_24 CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000002716 70.0
TLS2_k127_192684_3 alpha beta - - - 1.286e-223 711.0
TLS2_k127_192684_4 extracellular solute-binding protein, family 5 K02035,K13893 - - 1.761e-215 683.0
TLS2_k127_192684_5 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 614.0
TLS2_k127_192684_6 Periplasmic binding protein domain K10543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 528.0
TLS2_k127_192684_7 Branched-chain amino acid transport system / permease component K10544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 514.0
TLS2_k127_192684_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 498.0
TLS2_k127_192684_9 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 478.0
TLS2_k127_1927381_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1059.0
TLS2_k127_1927381_1 - - - - 1.325e-203 644.0
TLS2_k127_1927381_10 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007445 280.0
TLS2_k127_1927381_11 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000004066 278.0
TLS2_k127_1927381_12 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001991 250.0
TLS2_k127_1927381_13 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002422 239.0
TLS2_k127_1927381_14 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000001622 247.0
TLS2_k127_1927381_15 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000004735 218.0
TLS2_k127_1927381_16 - - - - 0.0000000000000000000000000000000000000000000000000000001111 203.0
TLS2_k127_1927381_17 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000005763 201.0
TLS2_k127_1927381_18 bacterial-type flagellum organization K02411 - - 0.000000000000000000000000000000000000000000000000001147 195.0
TLS2_k127_1927381_19 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000001485 188.0
TLS2_k127_1927381_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 596.0
TLS2_k127_1927381_20 Molybdate ABC transporter K02018 - - 0.0000000000000000000000000000000000000000000000000273 198.0
TLS2_k127_1927381_21 Belongs to the peptidase S1B family K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000001418 190.0
TLS2_k127_1927381_23 IPT/TIG domain - - - 0.000000000000000000000000000000000001176 149.0
TLS2_k127_1927381_24 - - - - 0.000000000000000000000000000005402 129.0
TLS2_k127_1927381_25 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000002597 113.0
TLS2_k127_1927381_26 bacterial-type flagellum organization K02411 - - 0.000000000000000000001907 100.0
TLS2_k127_1927381_27 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - 0.0000000004976 74.0
TLS2_k127_1927381_28 Sel1-like repeats. K07126 - - 0.0000000927 66.0
TLS2_k127_1927381_29 amidohydrolase - - - 0.000003079 61.0
TLS2_k127_1927381_3 MATE efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 514.0
TLS2_k127_1927381_4 WD-40 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 367.0
TLS2_k127_1927381_5 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 332.0
TLS2_k127_1927381_6 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 301.0
TLS2_k127_1927381_7 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004501 280.0
TLS2_k127_1927381_8 PBP superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001291 282.0
TLS2_k127_1927381_9 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003203 285.0
TLS2_k127_195997_0 ABC transporter - - - 1.19e-253 826.0
TLS2_k127_195997_1 regulation of response to stimulus - - - 7.886e-234 736.0
TLS2_k127_195997_11 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001499 255.0
TLS2_k127_195997_12 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000249 197.0
TLS2_k127_195997_13 bacterial-type flagellum organization K02411 - - 0.000000000000000000000000000000000000000000000007682 187.0
TLS2_k127_195997_14 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000000000000000000000000000000000000002354 194.0
TLS2_k127_195997_15 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000001172 177.0
TLS2_k127_195997_16 - - - - 0.00000000000000000000000000000002315 136.0
TLS2_k127_195997_17 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000007041 104.0
TLS2_k127_195997_18 Trypsin-like serine protease - - - 0.000000000000000000793 102.0
TLS2_k127_195997_19 - - - - 0.000000000000000002971 97.0
TLS2_k127_195997_2 4Fe-4S single cluster domain K06871 - - 4.601e-195 625.0
TLS2_k127_195997_20 ATPase family associated with various cellular activities (AAA) - - - 0.0000000005706 65.0
TLS2_k127_195997_21 bacterial-type flagellum organization K02411 - - 0.00002824 51.0
TLS2_k127_195997_3 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 510.0
TLS2_k127_195997_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 430.0
TLS2_k127_195997_5 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 420.0
TLS2_k127_195997_6 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 397.0
TLS2_k127_195997_7 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 370.0
TLS2_k127_195997_8 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003048 287.0
TLS2_k127_195997_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001683 272.0
TLS2_k127_1973652_0 FAD dependent oxidoreductase K09879 - - 3.476e-305 957.0
TLS2_k127_1973652_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 591.0
TLS2_k127_1973652_10 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 322.0
TLS2_k127_1973652_12 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001722 241.0
TLS2_k127_1973652_13 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000001045 221.0
TLS2_k127_1973652_15 PFAM Annexin repeat - - - 0.000000000000000000000000000000000000000000121 183.0
TLS2_k127_1973652_16 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000000000000002006 179.0
TLS2_k127_1973652_18 Subtilase family K01179,K13276 GO:0005575,GO:0005576 3.2.1.4 0.000000000000000000000000000001994 130.0
TLS2_k127_1973652_19 Macrocin-O-methyltransferase (TylF) K05303 - - 0.0000000000000000000000000001008 134.0
TLS2_k127_1973652_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 581.0
TLS2_k127_1973652_20 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000004646 122.0
TLS2_k127_1973652_21 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000009312 118.0
TLS2_k127_1973652_24 Somatomedin B domain - - - 0.000007508 57.0
TLS2_k127_1973652_25 CpXC protein - - - 0.0001641 52.0
TLS2_k127_1973652_4 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 500.0
TLS2_k127_1973652_5 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 487.0
TLS2_k127_1973652_6 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 508.0
TLS2_k127_1973652_7 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 431.0
TLS2_k127_1973652_8 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 402.0
TLS2_k127_1989008_0 heat shock protein binding - - - 0.0 1313.0
TLS2_k127_1989008_1 4 iron, 4 sulfur cluster binding - - - 0.0 1086.0
TLS2_k127_1989008_10 Bacterial extracellular solute-binding protein K10108,K15770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 527.0
TLS2_k127_1989008_11 Maltose transport system permease protein MalF P2 domain K10109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 532.0
TLS2_k127_1989008_12 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 522.0
TLS2_k127_1989008_13 Belongs to the glycosyl hydrolase 13 family K00701 - 2.4.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 535.0
TLS2_k127_1989008_14 Belongs to the ABC transporter superfamily K05816,K10111,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 499.0
TLS2_k127_1989008_15 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 449.0
TLS2_k127_1989008_16 LamB porin K02024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 456.0
TLS2_k127_1989008_17 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 415.0
TLS2_k127_1989008_18 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 413.0
TLS2_k127_1989008_19 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 398.0
TLS2_k127_1989008_2 Domain of unknown function (DUF3372) K01200 - 3.2.1.41 1.598e-290 929.0
TLS2_k127_1989008_20 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 391.0
TLS2_k127_1989008_21 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 348.0
TLS2_k127_1989008_22 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 332.0
TLS2_k127_1989008_23 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 315.0
TLS2_k127_1989008_24 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 291.0
TLS2_k127_1989008_25 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002369 278.0
TLS2_k127_1989008_26 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007654 277.0
TLS2_k127_1989008_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001106 251.0
TLS2_k127_1989008_28 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000001616 237.0
TLS2_k127_1989008_29 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000001187 218.0
TLS2_k127_1989008_3 Alpha-amylase domain K01176 - 3.2.1.1 1.508e-253 794.0
TLS2_k127_1989008_30 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000003605 212.0
TLS2_k127_1989008_31 Belongs to the SUA5 family K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000000000000000000000000000000000000000003995 206.0
TLS2_k127_1989008_34 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000001701 154.0
TLS2_k127_1989008_35 - - - - 0.0000000000000000000000000000000004542 138.0
TLS2_k127_1989008_37 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000009883 88.0
TLS2_k127_1989008_39 - - - - 0.0000551 49.0
TLS2_k127_1989008_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.782e-238 748.0
TLS2_k127_1989008_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.657e-227 707.0
TLS2_k127_1989008_6 Domain of unknown function (DUF4032) - - - 5.989e-198 623.0
TLS2_k127_1989008_7 Protein of unknown function (DUF1015) - - - 5.367e-197 626.0
TLS2_k127_1989008_8 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 597.0
TLS2_k127_1989008_9 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 533.0
TLS2_k127_2030622_0 COG0475 Kef-type K transport systems, membrane components - - - 2.753e-269 851.0
TLS2_k127_2030622_1 Cys Met metabolism K01761 - 4.4.1.11 8.968e-237 737.0
TLS2_k127_2030622_10 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 369.0
TLS2_k127_2030622_11 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 336.0
TLS2_k127_2030622_12 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006689 264.0
TLS2_k127_2030622_13 response regulator K09749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002683 250.0
TLS2_k127_2030622_14 ribonuclease BN - - - 0.000000000000000000000000000000000000000000000000000000000000523 235.0
TLS2_k127_2030622_15 - K07283 - - 0.00000000000000000000000000000000000001137 158.0
TLS2_k127_2030622_16 Histidine kinase - - - 0.0000000000000000000000000000000000005207 144.0
TLS2_k127_2030622_17 COG3209 Rhs family protein - - - 0.0000000000000003741 88.0
TLS2_k127_2030622_19 - - - - 0.0000009283 61.0
TLS2_k127_2030622_2 DNA modification methyltransferase - - - 1.276e-199 637.0
TLS2_k127_2030622_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 614.0
TLS2_k127_2030622_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 566.0
TLS2_k127_2030622_5 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 517.0
TLS2_k127_2030622_6 Belongs to the allantoicase family K01477 - 3.5.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 522.0
TLS2_k127_2030622_7 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 454.0
TLS2_k127_2030622_8 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 422.0
TLS2_k127_2030622_9 DNA/RNA non-specific endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 393.0
TLS2_k127_204627_0 lyase activity K01932 - - 0.0 1634.0
TLS2_k127_204627_1 A-macroglobulin complement component - - - 0.0 1594.0
TLS2_k127_204627_10 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.825e-253 802.0
TLS2_k127_204627_11 - - - - 3.571e-239 767.0
TLS2_k127_204627_12 Protein of unknown function (DUF1592) - - - 5.979e-223 704.0
TLS2_k127_204627_13 Protein of unknown function (DUF1552) - - - 7.38e-213 674.0
TLS2_k127_204627_15 cytochrome - - - 1.046e-196 633.0
TLS2_k127_204627_16 Chase2 domain K01768,K07315 - 3.1.3.3,4.6.1.1 3.381e-196 634.0
TLS2_k127_204627_17 SMART serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 632.0
TLS2_k127_204627_18 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 556.0
TLS2_k127_204627_19 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 547.0
TLS2_k127_204627_2 Capsule biosynthesis CapC K22116 - - 0.0 1212.0
TLS2_k127_204627_20 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 535.0
TLS2_k127_204627_21 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 550.0
TLS2_k127_204627_22 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 525.0
TLS2_k127_204627_23 Sigma-54 interaction domain K12266 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 515.0
TLS2_k127_204627_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 500.0
TLS2_k127_204627_25 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 482.0
TLS2_k127_204627_26 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 477.0
TLS2_k127_204627_27 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 470.0
TLS2_k127_204627_28 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 471.0
TLS2_k127_204627_29 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 466.0
TLS2_k127_204627_3 DNA helicase K03657 - 3.6.4.12 0.0 1178.0
TLS2_k127_204627_30 Spore coat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 448.0
TLS2_k127_204627_31 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 474.0
TLS2_k127_204627_32 PFAM cobalamin synthesis protein P47K - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 417.0
TLS2_k127_204627_33 Inositol monophosphatase family K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 406.0
TLS2_k127_204627_35 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 401.0
TLS2_k127_204627_36 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 377.0
TLS2_k127_204627_37 Heat shock 70 kDa protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 363.0
TLS2_k127_204627_38 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 359.0
TLS2_k127_204627_39 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 330.0
TLS2_k127_204627_40 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001117 292.0
TLS2_k127_204627_41 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001936 244.0
TLS2_k127_204627_43 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001599 231.0
TLS2_k127_204627_45 PFAM Fimbrial assembly family protein K02663 - - 0.000000000000000000000000000000000000000000000000000002012 202.0
TLS2_k127_204627_46 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000007812 193.0
TLS2_k127_204627_47 pilus assembly protein PilW K02672 - - 0.0000000000000000000000000000000000000000000000000002407 200.0
TLS2_k127_204627_49 Inner membrane component domain - - - 0.0000000000000000000000000000000000000000004477 160.0
TLS2_k127_204627_5 Zinc metalloprotease (Elastase) - - - 0.0 1071.0
TLS2_k127_204627_50 carbon utilization K02664,K02665,K12280 - - 0.000000000000000000000000000000000000000001074 166.0
TLS2_k127_204627_52 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000001756 171.0
TLS2_k127_204627_53 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000000000006697 148.0
TLS2_k127_204627_54 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000002254 134.0
TLS2_k127_204627_55 Pilus assembly protein PilX K02673 - - 0.000000000000000000000000000006602 128.0
TLS2_k127_204627_57 type IV pilus modification protein PilV K02671 - - 0.000000000000000000000279 102.0
TLS2_k127_204627_58 PFAM DSBA oxidoreductase - - - 0.000000000000000001242 88.0
TLS2_k127_204627_59 general secretion pathway protein K02456,K02459,K12285 - - 0.00000000000000001453 91.0
TLS2_k127_204627_6 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1038.0
TLS2_k127_204627_60 serine threonine protein kinase - - - 0.00000000000000004506 97.0
TLS2_k127_204627_61 amine dehydrogenase activity K20276 - - 0.00000005185 67.0
TLS2_k127_204627_7 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 2.051e-311 977.0
TLS2_k127_204627_8 Protein phosphatase 2A homologues, catalytic domain. - - - 3.913e-295 919.0
TLS2_k127_204627_9 Oxygen tolerance - - - 2.636e-255 826.0
TLS2_k127_2074488_0 GMC oxidoreductase K03333 - 1.1.3.6 6.798e-195 623.0
TLS2_k127_2074488_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 618.0
TLS2_k127_2074488_2 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 407.0
TLS2_k127_2074488_3 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 390.0
TLS2_k127_2074488_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 339.0
TLS2_k127_2074488_5 bacterial-type flagellum organization K02411 - - 0.000000000000278 81.0
TLS2_k127_2082958_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.0 1467.0
TLS2_k127_2082958_1 Family membership - - - 0.0 1369.0
TLS2_k127_2082958_10 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 595.0
TLS2_k127_2082958_11 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 581.0
TLS2_k127_2082958_12 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 557.0
TLS2_k127_2082958_13 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 494.0
TLS2_k127_2082958_14 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 503.0
TLS2_k127_2082958_15 Permease family K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 518.0
TLS2_k127_2082958_16 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 455.0
TLS2_k127_2082958_17 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 439.0
TLS2_k127_2082958_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1058.0
TLS2_k127_2082958_20 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 350.0
TLS2_k127_2082958_21 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 342.0
TLS2_k127_2082958_22 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 322.0
TLS2_k127_2082958_23 Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 303.0
TLS2_k127_2082958_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002883 285.0
TLS2_k127_2082958_26 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001258 275.0
TLS2_k127_2082958_27 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005209 263.0
TLS2_k127_2082958_28 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000172 248.0
TLS2_k127_2082958_29 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002766 244.0
TLS2_k127_2082958_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.357e-287 896.0
TLS2_k127_2082958_30 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000001041 220.0
TLS2_k127_2082958_31 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.0000000000000000000000000000000000000000008526 167.0
TLS2_k127_2082958_32 Prokaryotic N-terminal methylation motif K02650,K02655 - - 0.0000000000000000000000000000000000000258 151.0
TLS2_k127_2082958_33 ECF sigma factor K03088 - - 0.0000000000000000000000000000000001126 139.0
TLS2_k127_2082958_34 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000000000000000000000000002854 137.0
TLS2_k127_2082958_36 transcriptional regulator - - - 0.0000000000000000001349 97.0
TLS2_k127_2082958_37 - - - - 0.0000000000000000006347 99.0
TLS2_k127_2082958_38 outer membrane efflux protein K12340 - - 0.000000000000000009099 98.0
TLS2_k127_2082958_39 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000001303 96.0
TLS2_k127_2082958_4 alanine symporter K03310 - - 9.227e-244 765.0
TLS2_k127_2082958_40 - - - - 0.000000000000000075 84.0
TLS2_k127_2082958_41 WD40-like Beta Propeller Repeat - - - 0.0000000000000002356 93.0
TLS2_k127_2082958_42 Glutathione S-transferase, C-terminal domain K00799,K03599 - 2.5.1.18 0.00000004765 63.0
TLS2_k127_2082958_44 ABC-type transport auxiliary lipoprotein component - - - 0.0000008544 62.0
TLS2_k127_2082958_45 General secretion pathway protein G K02456 - - 0.00002238 53.0
TLS2_k127_2082958_47 nucleotidyltransferase K07076 - - 0.0001348 45.0
TLS2_k127_2082958_48 23S rRNA-intervening sequence protein - - - 0.0001671 51.0
TLS2_k127_2082958_5 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 3.129e-221 693.0
TLS2_k127_2082958_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 2.299e-216 698.0
TLS2_k127_2082958_7 FtsX-like permease family - - - 1.227e-206 652.0
TLS2_k127_2082958_8 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 608.0
TLS2_k127_2082958_9 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 594.0
TLS2_k127_2164737_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0 1546.0
TLS2_k127_2164737_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0 1526.0
TLS2_k127_2164737_2 Penicillinase repressor - - - 0.000000000000000000000000000000000000000002461 161.0
TLS2_k127_2164737_3 Peptidase family M48 - - - 0.0000000000000000000000000000000000003555 151.0
TLS2_k127_2211707_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 2.416e-212 666.0
TLS2_k127_2211707_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 3.125e-194 640.0
TLS2_k127_2211707_2 Tryptophan-rich sensory protein K05770 - - 0.000000000000000000000000000000000000000005941 162.0
TLS2_k127_2211707_4 - - - - 0.00001363 54.0
TLS2_k127_2224751_0 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 434.0
TLS2_k127_2224751_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003127 273.0
TLS2_k127_2227160_0 Pfam:HxxPF_rpt - - - 0.0 1088.0
TLS2_k127_2227160_1 Beta-lactamase - - - 1.647e-252 781.0
TLS2_k127_2227160_10 HicB family - - - 0.0000000000000000000000000000000000000000001164 166.0
TLS2_k127_2227160_11 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000001125 169.0
TLS2_k127_2227160_13 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000009666 138.0
TLS2_k127_2227160_14 - - - - 0.00000000000000000000000000000001185 144.0
TLS2_k127_2227160_15 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000004894 130.0
TLS2_k127_2227160_16 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000001946 104.0
TLS2_k127_2227160_18 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000002557 76.0
TLS2_k127_2227160_19 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000009083 86.0
TLS2_k127_2227160_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 4.098e-241 769.0
TLS2_k127_2227160_20 transposition K07497 - - 0.000000001509 59.0
TLS2_k127_2227160_21 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00002538 57.0
TLS2_k127_2227160_3 Aldehyde dehydrogenase family K02618,K15514 - 1.2.1.77,1.2.1.91,3.3.2.12 5.499e-232 733.0
TLS2_k127_2227160_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 526.0
TLS2_k127_2227160_5 PFAM PHP domain protein K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 319.0
TLS2_k127_2227160_6 ATPase involved in DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 332.0
TLS2_k127_2227160_7 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007104 284.0
TLS2_k127_2227160_8 AAA domain - - - 0.000000000000000000000000000000000000000000000000003762 195.0
TLS2_k127_2227160_9 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000000000000000000000000000000001001 198.0
TLS2_k127_2232602_0 Tricorn protease homolog K08676 - - 0.0 1677.0
TLS2_k127_2232602_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol - - - 7.527e-219 691.0
TLS2_k127_2232602_10 beta-lactamase activity K01058,K07502 - 3.1.1.32,3.1.1.4 0.000000000000000000000000002827 126.0
TLS2_k127_2232602_11 Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) K07754 GO:0001654,GO:0001754,GO:0003407,GO:0003674,GO:0003824,GO:0004800,GO:0005575,GO:0005623,GO:0005886,GO:0006575,GO:0006590,GO:0006725,GO:0006807,GO:0006915,GO:0007275,GO:0007399,GO:0007423,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009653,GO:0009887,GO:0009987,GO:0010721,GO:0010817,GO:0012501,GO:0016020,GO:0016491,GO:0018958,GO:0019336,GO:0019439,GO:0022008,GO:0022603,GO:0030154,GO:0030182,GO:0032501,GO:0032502,GO:0033798,GO:0040008,GO:0040014,GO:0040018,GO:0042219,GO:0042403,GO:0042404,GO:0042445,GO:0042447,GO:0042461,GO:0042462,GO:0042478,GO:0042480,GO:0042670,GO:0043010,GO:0044237,GO:0044248,GO:0044464,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045927,GO:0046530,GO:0046532,GO:0046533,GO:0046549,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048523,GO:0048592,GO:0048593,GO:0048638,GO:0048639,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051094,GO:0051239,GO:0051240,GO:0051241,GO:0051402,GO:0051960,GO:0051961,GO:0055114,GO:0060041,GO:0060042,GO:0060219,GO:0060284,GO:0065007,GO:0065008,GO:0070997,GO:0071704,GO:0071944,GO:0090596,GO:0097474,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901615,GO:1901616,GO:1990009,GO:2000026,GO:2000027 1.21.99.3 0.000000000000000000001747 107.0
TLS2_k127_2232602_13 Thioredoxin-like - - - 0.00000000002953 72.0
TLS2_k127_2232602_15 Domain of unknown function (DUF4041) - - - 0.0000000004938 63.0
TLS2_k127_2232602_2 Alpha amylase catalytic K00701 - 2.4.1.19 1.364e-196 636.0
TLS2_k127_2232602_3 Protein of unknown function (DUF1573) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 616.0
TLS2_k127_2232602_4 Protein of unknown function (DUF4011) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 417.0
TLS2_k127_2232602_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004002 248.0
TLS2_k127_2232602_7 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000005857 236.0
TLS2_k127_2232602_8 MAPEG family - - - 0.0000000000000000000000000000000000000003398 153.0
TLS2_k127_2232602_9 Protein of unknown function (DUF1573) - - - 0.0000000000000000000000000000000000005015 141.0
TLS2_k127_2306515_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1246.0
TLS2_k127_2306515_1 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.0 1108.0
TLS2_k127_2306515_10 KAP family P-loop domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 314.0
TLS2_k127_2306515_11 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 292.0
TLS2_k127_2306515_12 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 313.0
TLS2_k127_2306515_13 Ferredoxin thioredoxin reductase catalytic beta chain K17892 - 1.8.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001477 263.0
TLS2_k127_2306515_14 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005272 268.0
TLS2_k127_2306515_15 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006954 273.0
TLS2_k127_2306515_16 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000001415 232.0
TLS2_k127_2306515_17 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000002421 180.0
TLS2_k127_2306515_18 ferrous iron binding K06990,K15755 - - 0.00000000000000000000000000000000000000000000006594 181.0
TLS2_k127_2306515_19 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000009639 147.0
TLS2_k127_2306515_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1050.0
TLS2_k127_2306515_20 bacterial-type flagellum organization - - - 0.00000000000003965 76.0
TLS2_k127_2306515_21 Outer membrane protein beta-barrel domain - - - 0.00000000000179 76.0
TLS2_k127_2306515_22 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000002282 76.0
TLS2_k127_2306515_23 sodium:proton antiporter activity K06382 - 3.1.3.16 0.0000001477 64.0
TLS2_k127_2306515_3 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 - 3.2.1.141 3.386e-224 709.0
TLS2_k127_2306515_4 PFAM Cytochrome c, class I - - - 3.613e-222 700.0
TLS2_k127_2306515_5 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 2.89e-216 681.0
TLS2_k127_2306515_6 TIGRFAM cysteine-rich repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 483.0
TLS2_k127_2306515_7 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 488.0
TLS2_k127_2306515_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 333.0
TLS2_k127_2306515_9 acyl-CoA hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 347.0
TLS2_k127_2337_0 Luciferase-like monooxygenase K18660 - - 1.17e-274 943.0
TLS2_k127_2337_1 Ketoacyl-synthetase C-terminal extension - - - 3.457e-271 868.0
TLS2_k127_2337_10 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000003033 225.0
TLS2_k127_2337_11 WD-40 repeat - - - 0.0000000000000000000000001493 123.0
TLS2_k127_2337_2 non-ribosomal peptide synthetase K16416 - - 2.35e-268 864.0
TLS2_k127_2337_3 WD-40 repeat - - - 5.664e-232 749.0
TLS2_k127_2337_4 PFAM Archaeal ATPase - - - 3.405e-218 688.0
TLS2_k127_2337_5 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 628.0
TLS2_k127_2337_6 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 548.0
TLS2_k127_2337_7 ABC transporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 498.0
TLS2_k127_2337_8 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 347.0
TLS2_k127_2337_9 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 321.0
TLS2_k127_2373537_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1490.0
TLS2_k127_2373537_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1407.0
TLS2_k127_2373537_10 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 479.0
TLS2_k127_2373537_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 458.0
TLS2_k127_2373537_12 histone H2A K63-linked ubiquitination K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 470.0
TLS2_k127_2373537_13 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 455.0
TLS2_k127_2373537_14 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 447.0
TLS2_k127_2373537_15 Nucleoside-binding outer membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 422.0
TLS2_k127_2373537_16 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 424.0
TLS2_k127_2373537_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 379.0
TLS2_k127_2373537_18 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 323.0
TLS2_k127_2373537_19 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002983 277.0
TLS2_k127_2373537_2 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 6.522e-288 892.0
TLS2_k127_2373537_20 Endonuclease I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000291 265.0
TLS2_k127_2373537_21 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000004488 205.0
TLS2_k127_2373537_22 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000004137 174.0
TLS2_k127_2373537_23 YjbR - - - 0.00000000000000000000000000000048 132.0
TLS2_k127_2373537_24 bacterial-type flagellum organization K02411 - - 0.00000000000000000001663 98.0
TLS2_k127_2373537_25 - - - - 0.00000000000000000006145 98.0
TLS2_k127_2373537_27 Band 7 protein K07192 - - 0.0000000001042 76.0
TLS2_k127_2373537_28 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0000004459 63.0
TLS2_k127_2373537_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 1.825e-247 779.0
TLS2_k127_2373537_4 ABC transporter K02056 - 3.6.3.17 1.329e-228 719.0
TLS2_k127_2373537_5 Esterase-like activity of phytase K01083,K07004 - 3.1.3.8 6.653e-209 672.0
TLS2_k127_2373537_6 protein kinase activity - - - 1.411e-206 664.0
TLS2_k127_2373537_7 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 582.0
TLS2_k127_2373537_8 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 488.0
TLS2_k127_2373537_9 Sh3 type 3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 498.0
TLS2_k127_2400879_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1256.0
TLS2_k127_2400879_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.144e-317 981.0
TLS2_k127_2400879_10 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 451.0
TLS2_k127_2400879_11 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 448.0
TLS2_k127_2400879_12 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 442.0
TLS2_k127_2400879_13 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 451.0
TLS2_k127_2400879_14 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 400.0
TLS2_k127_2400879_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 410.0
TLS2_k127_2400879_16 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 394.0
TLS2_k127_2400879_17 Belongs to the pseudouridine synthase RluA family K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 411.0
TLS2_k127_2400879_18 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 370.0
TLS2_k127_2400879_19 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 357.0
TLS2_k127_2400879_2 Trypsin-like peptidase domain - - - 1.02e-228 734.0
TLS2_k127_2400879_20 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 358.0
TLS2_k127_2400879_21 protein trimerization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 348.0
TLS2_k127_2400879_22 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 347.0
TLS2_k127_2400879_23 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 330.0
TLS2_k127_2400879_24 Protein conserved in bacteria K09939 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 307.0
TLS2_k127_2400879_25 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 304.0
TLS2_k127_2400879_26 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 301.0
TLS2_k127_2400879_27 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001407 279.0
TLS2_k127_2400879_28 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002825 279.0
TLS2_k127_2400879_29 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001727 255.0
TLS2_k127_2400879_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 3.696e-222 710.0
TLS2_k127_2400879_30 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005483 257.0
TLS2_k127_2400879_31 PFAM Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000004044 236.0
TLS2_k127_2400879_33 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000001351 145.0
TLS2_k127_2400879_34 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000002062 136.0
TLS2_k127_2400879_39 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000003318 74.0
TLS2_k127_2400879_4 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 571.0
TLS2_k127_2400879_40 Thiamine-binding protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000001861 71.0
TLS2_k127_2400879_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 540.0
TLS2_k127_2400879_6 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 507.0
TLS2_k127_2400879_7 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 493.0
TLS2_k127_2400879_8 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 477.0
TLS2_k127_2400879_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 475.0
TLS2_k127_2534919_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 621.0
TLS2_k127_2534919_1 Phage tail sheath protein subtilisin-like domain K06907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 602.0
TLS2_k127_2534919_11 - - - - 0.000000000000000000000000000000000000000000000000000132 199.0
TLS2_k127_2534919_13 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000001316 139.0
TLS2_k127_2534919_16 AAA ATPase domain - - - 0.0000000000000000000009075 110.0
TLS2_k127_2534919_19 Phage baseplate assembly protein W K06903 - - 0.00000000000000004901 92.0
TLS2_k127_2534919_2 Baseplate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 596.0
TLS2_k127_2534919_20 SMART Integrin alpha beta-propellor repeat protein - - - 0.0000000000000007709 77.0
TLS2_k127_2534919_21 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000009779 76.0
TLS2_k127_2534919_22 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000346 61.0
TLS2_k127_2534919_23 23S rRNA-intervening sequence protein - - - 0.0000271 53.0
TLS2_k127_2534919_4 protocatechuate 3,4-dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 395.0
TLS2_k127_2534919_5 Late control gene D protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 402.0
TLS2_k127_2534919_6 Rhs element vgr protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 362.0
TLS2_k127_2540114_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000008781 247.0
TLS2_k127_2540114_1 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000005146 216.0
TLS2_k127_2540114_2 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000524 174.0
TLS2_k127_2540114_3 amino acid activation for nonribosomal peptide biosynthetic process K03651,K05889,K12132 - 1.1.2.6,2.7.11.1,3.1.4.53 0.00000000000000000000000000002631 137.0
TLS2_k127_2594225_0 Sulfatase K01133 - 3.1.6.6 0.0 1042.0
TLS2_k127_2594225_1 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 3.416e-255 814.0
TLS2_k127_2594225_10 vancomycin resistance protein K18346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 525.0
TLS2_k127_2594225_11 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 512.0
TLS2_k127_2594225_12 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 516.0
TLS2_k127_2594225_13 tRNA synthetases class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 514.0
TLS2_k127_2594225_14 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 507.0
TLS2_k127_2594225_15 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 509.0
TLS2_k127_2594225_16 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 531.0
TLS2_k127_2594225_17 Glycosyl transferases group 1 K06320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 502.0
TLS2_k127_2594225_18 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 445.0
TLS2_k127_2594225_19 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 435.0
TLS2_k127_2594225_2 PBS lyase HEAT-like repeat - - - 5.76e-251 811.0
TLS2_k127_2594225_21 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 432.0
TLS2_k127_2594225_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 424.0
TLS2_k127_2594225_24 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 424.0
TLS2_k127_2594225_25 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 386.0
TLS2_k127_2594225_26 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 375.0
TLS2_k127_2594225_28 Protein of unknown function (DUF1698) K15257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 362.0
TLS2_k127_2594225_29 Rhs element Vgr protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 327.0
TLS2_k127_2594225_3 Sulfatase - - - 4.365e-245 782.0
TLS2_k127_2594225_30 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 329.0
TLS2_k127_2594225_31 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 337.0
TLS2_k127_2594225_32 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 295.0
TLS2_k127_2594225_33 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003734 281.0
TLS2_k127_2594225_34 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000002259 280.0
TLS2_k127_2594225_35 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005156 261.0
TLS2_k127_2594225_36 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000006468 284.0
TLS2_k127_2594225_37 FHA domain - - - 0.000000000000000000000000000000000000000000000000000000000000009422 220.0
TLS2_k127_2594225_38 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000007589 223.0
TLS2_k127_2594225_39 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000000000002757 231.0
TLS2_k127_2594225_4 7TM receptor with intracellular HD hydrolase K07037 - - 7.514e-238 761.0
TLS2_k127_2594225_40 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000001926 207.0
TLS2_k127_2594225_41 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000003637 204.0
TLS2_k127_2594225_43 - - - - 0.0000000000000000000000000000000000000000000000000435 205.0
TLS2_k127_2594225_44 Belongs to the Dps family - - - 0.0000000000000000000000000000000000000000207 164.0
TLS2_k127_2594225_45 ThiS family K03636 - - 0.000000000000000000000000000000000000001418 151.0
TLS2_k127_2594225_46 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.0000000000000000000000000000000000001513 155.0
TLS2_k127_2594225_49 - - - - 0.0000000000000000000000000001487 124.0
TLS2_k127_2594225_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 1.927e-237 742.0
TLS2_k127_2594225_51 - - - - 0.00000000000000000000000009198 109.0
TLS2_k127_2594225_52 Sulfurtransferase TusA - - - 0.000000000000000000000008365 106.0
TLS2_k127_2594225_54 - - - - 0.0000000000000000000008913 107.0
TLS2_k127_2594225_56 Prokaryotic homologs of the JAB domain - - - 0.0000000000000000866 87.0
TLS2_k127_2594225_57 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000002415 89.0
TLS2_k127_2594225_58 NIL - - - 0.00000000001892 67.0
TLS2_k127_2594225_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 629.0
TLS2_k127_2594225_61 CpXC protein - - - 0.000001114 62.0
TLS2_k127_2594225_7 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 559.0
TLS2_k127_2594225_8 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 541.0
TLS2_k127_2594225_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 527.0
TLS2_k127_2667474_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 411.0
TLS2_k127_2667474_1 TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 396.0
TLS2_k127_2667474_2 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 339.0
TLS2_k127_2667474_3 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 325.0
TLS2_k127_2667474_4 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 331.0
TLS2_k127_2667474_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 295.0
TLS2_k127_2667474_6 Domain of unknown function (DUF4280) - - - 0.000000000000002961 77.0
TLS2_k127_2667474_8 IMP dehydrogenase activity - - - 0.000000000001603 78.0
TLS2_k127_2676655_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 2.977e-217 685.0
TLS2_k127_2676655_1 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 1.635e-195 644.0
TLS2_k127_2676655_10 - - - - 0.000000000000000000006437 103.0
TLS2_k127_2676655_11 Multisubunit Na H antiporter MnhC subunit K05567 - - 0.00000000000000000002273 105.0
TLS2_k127_2676655_12 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.00000000000000000009448 100.0
TLS2_k127_2676655_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 467.0
TLS2_k127_2676655_3 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 447.0
TLS2_k127_2676655_4 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 391.0
TLS2_k127_2676655_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 310.0
TLS2_k127_2676655_6 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 306.0
TLS2_k127_2676655_7 Domain related to MnhB subunit of Na+/H+ antiporter - - - 0.000000000000000000000000000000000000000000000000000000000000005055 233.0
TLS2_k127_2676655_8 PFAM Na H antiporter subunit K05571 - - 0.000000000000000000000000000002059 123.0
TLS2_k127_2676655_9 Na+/H+ ion antiporter subunit K05569 - - 0.00000000000000000000002478 106.0
TLS2_k127_2676689_0 FAD linked oxidase domain protein K06911 - - 0.0 1185.0
TLS2_k127_2676689_1 Thiamine pyrophosphate enzyme, central domain K00156 - 1.2.5.1 9.203e-293 911.0
TLS2_k127_2676689_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 498.0
TLS2_k127_2676689_11 SMART Integrin alpha beta-propellor repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 465.0
TLS2_k127_2676689_12 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 422.0
TLS2_k127_2676689_13 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 428.0
TLS2_k127_2676689_14 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 415.0
TLS2_k127_2676689_15 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 413.0
TLS2_k127_2676689_18 PFAM glutaredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 395.0
TLS2_k127_2676689_19 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 389.0
TLS2_k127_2676689_2 GAF domain - - - 1.796e-278 868.0
TLS2_k127_2676689_20 Uncharacterised protein family (UPF0158) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 351.0
TLS2_k127_2676689_21 PFAM Silent information regulator protein Sir2 K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 346.0
TLS2_k127_2676689_22 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004601 282.0
TLS2_k127_2676689_23 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin K00365 - 1.7.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001831 282.0
TLS2_k127_2676689_25 Extensin-like protein C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000154 261.0
TLS2_k127_2676689_26 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000003122 245.0
TLS2_k127_2676689_27 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000001922 239.0
TLS2_k127_2676689_28 PFAM polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003726 249.0
TLS2_k127_2676689_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.076e-262 833.0
TLS2_k127_2676689_30 Protein of unknown function (DUF1643) - - - 0.000000000000000000000000000000000000000000000000000000001005 210.0
TLS2_k127_2676689_31 - - - - 0.0000000000000000000000000000000000000000000000000000001474 201.0
TLS2_k127_2676689_32 Anabaena sensory rhodopsin transducer - - - 0.00000000000000000000000000000000000000000000000003496 198.0
TLS2_k127_2676689_34 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000002403 166.0
TLS2_k127_2676689_35 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.00000000000000000000000000000000000004913 149.0
TLS2_k127_2676689_36 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000001775 134.0
TLS2_k127_2676689_37 Histidine kinase - - - 0.0000000000000000000000000000000007202 135.0
TLS2_k127_2676689_38 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000215 141.0
TLS2_k127_2676689_39 chaperone-mediated protein folding - - - 0.00000000000000000000000000000008615 130.0
TLS2_k127_2676689_4 GMC oxidoreductase K03333 - 1.1.3.6 3.968e-249 784.0
TLS2_k127_2676689_40 Cytochrome c - - - 0.000000000000000000000000000007175 134.0
TLS2_k127_2676689_41 Iron-binding zinc finger CDGSH type K05710 - - 0.00000000000000000000000000009324 124.0
TLS2_k127_2676689_42 self proteolysis - - - 0.000000000000000000000004237 113.0
TLS2_k127_2676689_43 PIN domain - - - 0.0000000000000000000003344 102.0
TLS2_k127_2676689_44 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0000000000000008375 83.0
TLS2_k127_2676689_45 - - - - 0.000000000000002199 89.0
TLS2_k127_2676689_46 positive regulation of growth - - - 0.0000000001534 74.0
TLS2_k127_2676689_47 deoxyhypusine monooxygenase activity - - - 0.0000001695 64.0
TLS2_k127_2676689_48 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00021 52.0
TLS2_k127_2676689_5 ABC-type uncharacterized transport system K01992 - - 3.145e-244 777.0
TLS2_k127_2676689_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 9.628e-238 748.0
TLS2_k127_2676689_7 Glycosyl hydrolases family 15 - - - 5.133e-225 732.0
TLS2_k127_2676689_8 GTP-binding protein K06207 - - 2.547e-203 638.0
TLS2_k127_2676689_9 Splits dipeptides with a prolyl residue in the C- terminal position K01271 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 567.0
TLS2_k127_2695470_0 DEAD DEAH box K03724 - - 0.0 1770.0
TLS2_k127_2695470_1 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.0 1047.0
TLS2_k127_2695470_10 Belongs to the ompA family K03286 - - 0.000000000000000000000000004589 123.0
TLS2_k127_2695470_13 Outer membrane protein beta-barrel domain - - - 0.00000000000496 77.0
TLS2_k127_2695470_2 Transporter - - - 8.265e-227 716.0
TLS2_k127_2695470_3 Belongs to the 'phage' integrase family K14059 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 475.0
TLS2_k127_2695470_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 371.0
TLS2_k127_2695470_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 357.0
TLS2_k127_2695470_6 TIGRFAM cysteine-rich repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 332.0
TLS2_k127_2695470_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000005601 249.0
TLS2_k127_2695470_8 heme binding K06194,K06401,K21472,K21473 - - 0.00000000000000000000000000000000000000000000000000000002506 205.0
TLS2_k127_2695470_9 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000002813 127.0
TLS2_k127_269713_0 non-ribosomal peptide synthetase - - - 0.0 1574.0
TLS2_k127_269713_1 Pfam:HxxPF_rpt - - - 0.0 1175.0
TLS2_k127_269713_10 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 556.0
TLS2_k127_269713_11 Lyase K01857 - 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 531.0
TLS2_k127_269713_12 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 484.0
TLS2_k127_269713_13 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 431.0
TLS2_k127_269713_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 377.0
TLS2_k127_269713_15 Ndr family K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 350.0
TLS2_k127_269713_16 Encapsulating protein for peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 336.0
TLS2_k127_269713_17 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 332.0
TLS2_k127_269713_18 protocatechuate 3,4-dioxygenase, beta subunit K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 303.0
TLS2_k127_269713_19 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002774 311.0
TLS2_k127_269713_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 8.596e-295 914.0
TLS2_k127_269713_20 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001673 292.0
TLS2_k127_269713_21 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007786 261.0
TLS2_k127_269713_22 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001592 234.0
TLS2_k127_269713_23 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000000000000001589 159.0
TLS2_k127_269713_24 MgtC SapB transporter K07507 - - 0.000000000000000000000000000000000000002051 153.0
TLS2_k127_269713_25 Dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000000000001206 142.0
TLS2_k127_269713_26 Peptidase M50B-like - - - 0.00000000000000000000000000000003233 135.0
TLS2_k127_269713_27 Tetratricopeptide repeat - - - 0.0000000000000000000000000000008644 137.0
TLS2_k127_269713_28 phage tail tape measure protein - - - 0.000000000000000000007913 109.0
TLS2_k127_269713_29 PFAM Archaeal ATPase - - - 0.000000000000008105 75.0
TLS2_k127_269713_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.347e-269 852.0
TLS2_k127_269713_30 - - - - 0.000000000000203 76.0
TLS2_k127_269713_31 HNH nucleases - - - 0.000002198 52.0
TLS2_k127_269713_4 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 6.489e-222 700.0
TLS2_k127_269713_5 Rieske [2Fe-2S] domain - - - 7.428e-213 669.0
TLS2_k127_269713_6 Ketoacyl-synthetase C-terminal extension - - - 9.459e-213 748.0
TLS2_k127_269713_7 Bacterial regulatory protein, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 601.0
TLS2_k127_269713_8 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 608.0
TLS2_k127_269713_9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 535.0
TLS2_k127_2777924_0 oligopeptide transporter, OPT family - - - 0.0 1030.0
TLS2_k127_2777924_1 ABC transporter - - - 3.155e-307 945.0
TLS2_k127_2777924_10 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 396.0
TLS2_k127_2777924_11 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 370.0
TLS2_k127_2777924_12 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 376.0
TLS2_k127_2777924_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 334.0
TLS2_k127_2777924_14 Radical SAM superfamily K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 337.0
TLS2_k127_2777924_15 helix_turn_helix, mercury resistance K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 306.0
TLS2_k127_2777924_16 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007279 265.0
TLS2_k127_2777924_17 FHA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001213 249.0
TLS2_k127_2777924_18 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000005208 240.0
TLS2_k127_2777924_19 Domain of unknown function (DUF4276) - - - 0.0000000000000000000000000000000000000000000000000000000000000008238 237.0
TLS2_k127_2777924_2 SMART serine threonine protein kinase K12132 - 2.7.11.1 4.556e-300 955.0
TLS2_k127_2777924_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000002203 216.0
TLS2_k127_2777924_21 PFAM regulatory protein, ArsR - - - 0.00000000000000000000000000000000000000000000000000000000001134 207.0
TLS2_k127_2777924_22 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000002194 234.0
TLS2_k127_2777924_23 response to antibiotic - - - 0.00000000000000000000000000000000000000000000000000001043 218.0
TLS2_k127_2777924_24 metallopeptidase activity K06889 - - 0.000000000000000000000000000000000000000000000000001372 209.0
TLS2_k127_2777924_26 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000003164 197.0
TLS2_k127_2777924_27 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000001234 194.0
TLS2_k127_2777924_28 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000002297 156.0
TLS2_k127_2777924_29 rna polymerase sigma factor - - - 0.000000000000000000000000000000000000005791 154.0
TLS2_k127_2777924_3 serine threonine protein kinase - - - 3.213e-287 927.0
TLS2_k127_2777924_30 ChrR Cupin-like domain K07167 - - 0.0000000000000000000000000000000000003087 148.0
TLS2_k127_2777924_31 Belongs to the FPP GGPP synthase family - - - 0.00000000000000000000000000000000005127 154.0
TLS2_k127_2777924_32 - - - - 0.0000000000000000000000000000000002178 145.0
TLS2_k127_2777924_33 TIGRFAM cysteine-rich repeat protein - - - 0.000000000000000000000203 106.0
TLS2_k127_2777924_34 TRAP transporter T-component - - - 0.00000000000000000004722 101.0
TLS2_k127_2777924_35 Amidohydrolase family - - - 0.0000000000001372 86.0
TLS2_k127_2777924_36 RNA recognition motif K12893,K14651 GO:0000375,GO:0000377,GO:0000398,GO:0001067,GO:0001069,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008143,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0045292,GO:0046483,GO:0070717,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000004635 69.0
TLS2_k127_2777924_37 Psort location Cytoplasmic, score 8.96 - - - 0.0000002311 61.0
TLS2_k127_2777924_38 extracellular nuclease K07004 - - 0.000001442 59.0
TLS2_k127_2777924_39 - - - - 0.00003408 53.0
TLS2_k127_2777924_4 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 1.77e-256 809.0
TLS2_k127_2777924_40 Protein of unknown function (DUF1036) - - - 0.0001 52.0
TLS2_k127_2777924_5 AAA domain, putative AbiEii toxin, Type IV TA system - - - 2.745e-231 723.0
TLS2_k127_2777924_6 cellulose binding - - - 2.481e-197 646.0
TLS2_k127_2777924_7 lycopene cyclase K06443 - 5.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 507.0
TLS2_k127_2777924_8 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 414.0
TLS2_k127_2777924_9 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 421.0
TLS2_k127_2820152_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1448.0
TLS2_k127_2820152_1 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1310.0
TLS2_k127_2820152_10 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 526.0
TLS2_k127_2820152_11 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 535.0
TLS2_k127_2820152_12 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 516.0
TLS2_k127_2820152_13 GMC oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 506.0
TLS2_k127_2820152_14 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 477.0
TLS2_k127_2820152_15 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 484.0
TLS2_k127_2820152_16 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 476.0
TLS2_k127_2820152_17 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 444.0
TLS2_k127_2820152_18 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 438.0
TLS2_k127_2820152_19 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 460.0
TLS2_k127_2820152_2 Heat shock 70 kDa protein K04043 - - 0.0 1050.0
TLS2_k127_2820152_20 Family membership - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 424.0
TLS2_k127_2820152_21 Penicillin-insensitive murein endopeptidase K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 403.0
TLS2_k127_2820152_22 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 411.0
TLS2_k127_2820152_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 403.0
TLS2_k127_2820152_24 two-component system, chemotaxis family, sensor kinase CheA with response regulator domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 424.0
TLS2_k127_2820152_25 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 392.0
TLS2_k127_2820152_26 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 372.0
TLS2_k127_2820152_27 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 370.0
TLS2_k127_2820152_28 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 351.0
TLS2_k127_2820152_29 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 341.0
TLS2_k127_2820152_3 Heat shock 70 kDa protein K04043 - - 3.376e-297 922.0
TLS2_k127_2820152_30 AIPR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 332.0
TLS2_k127_2820152_31 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 331.0
TLS2_k127_2820152_32 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 307.0
TLS2_k127_2820152_33 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 300.0
TLS2_k127_2820152_34 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001143 286.0
TLS2_k127_2820152_35 Iron-storage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
TLS2_k127_2820152_36 Transcriptional activator of acetoin glycerol metabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003309 274.0
TLS2_k127_2820152_37 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001506 266.0
TLS2_k127_2820152_38 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009295 266.0
TLS2_k127_2820152_39 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000001792 253.0
TLS2_k127_2820152_4 heat shock protein binding - - - 5.56e-283 899.0
TLS2_k127_2820152_40 PFAM response regulator receiver K02485 - - 0.0000000000000000000000000000000000000000000000000000000216 201.0
TLS2_k127_2820152_41 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000009247 199.0
TLS2_k127_2820152_42 protein, possibly involved in aromatic compounds catabolism K02614 - - 0.00000000000000000000000000000000000000000000006432 173.0
TLS2_k127_2820152_43 Transcription elongation factor, GreA/GreB, C-term - - - 0.0000000000000000000000000000000000000000000004367 179.0
TLS2_k127_2820152_44 Histidine kinase K02660,K03406,K11525 - - 0.0000000000000000000000000000000000000000003455 183.0
TLS2_k127_2820152_45 - - - - 0.00000000000000000000000000000000000000005937 163.0
TLS2_k127_2820152_47 tigr02147 - - - 0.00000000000000000000000000000000000002197 165.0
TLS2_k127_2820152_48 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000009315 162.0
TLS2_k127_2820152_5 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 7.385e-282 885.0
TLS2_k127_2820152_50 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000008822 130.0
TLS2_k127_2820152_52 Thioesterase superfamily - - - 0.000000000000000000000001297 110.0
TLS2_k127_2820152_53 cheY-homologous receiver domain K02490 - - 0.00000000000000000004069 102.0
TLS2_k127_2820152_54 Phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000005071 94.0
TLS2_k127_2820152_55 phospho-2-dehydro-3-deoxyheptonate aldolase - - - 0.0000000000000007775 89.0
TLS2_k127_2820152_56 PFAM CheW domain protein K03408 - - 0.0000000000000009328 86.0
TLS2_k127_2820152_58 Phosphopantetheine attachment site K02078 - - 0.00000005806 58.0
TLS2_k127_2820152_59 Histidine kinase - - - 0.0000002632 52.0
TLS2_k127_2820152_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.186e-235 743.0
TLS2_k127_2820152_60 - - - - 0.000002557 59.0
TLS2_k127_2820152_61 30S ribosomal protein S23 - - - 0.0000139 54.0
TLS2_k127_2820152_62 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00003596 52.0
TLS2_k127_2820152_63 Oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00007506 54.0
TLS2_k127_2820152_7 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 5.853e-213 678.0
TLS2_k127_2820152_8 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 1.169e-195 619.0
TLS2_k127_2844497_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1444.0
TLS2_k127_2844497_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1043.0
TLS2_k127_2844497_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 471.0
TLS2_k127_2844497_11 FAD binding domain K00486 - 1.14.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 469.0
TLS2_k127_2844497_12 Surface antigen K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 447.0
TLS2_k127_2844497_13 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 398.0
TLS2_k127_2844497_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 338.0
TLS2_k127_2844497_16 CotH kinase protein K06330 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 335.0
TLS2_k127_2844497_17 molybdenum cofactor biosynthesis protein B K03638,K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 294.0
TLS2_k127_2844497_18 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 292.0
TLS2_k127_2844497_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003783 286.0
TLS2_k127_2844497_2 PFAM Protein kinase domain - - - 1.204e-299 960.0
TLS2_k127_2844497_20 Phosphotransferase enzyme family K06979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006123 297.0
TLS2_k127_2844497_21 3-hydroxyanthranilic acid dioxygenase K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000005616 269.0
TLS2_k127_2844497_22 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000006659 252.0
TLS2_k127_2844497_23 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003002 243.0
TLS2_k127_2844497_24 Endoribonuclease L-PSP K15067 - 3.5.99.5 0.00000000000000000000000000000000000000000000000000000000000000002468 228.0
TLS2_k127_2844497_25 arylformamidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000005363 235.0
TLS2_k127_2844497_26 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000009764 217.0
TLS2_k127_2844497_27 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000004197 207.0
TLS2_k127_2844497_28 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000000000000000000000000000001133 197.0
TLS2_k127_2844497_29 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000002984 191.0
TLS2_k127_2844497_3 Belongs to the aldehyde dehydrogenase family K10217 - 1.2.1.32,1.2.1.85 2.855e-195 635.0
TLS2_k127_2844497_30 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000002854 189.0
TLS2_k127_2844497_32 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000001126 196.0
TLS2_k127_2844497_33 S4 RNA-binding domain K04762 - - 0.0000000000000000000000000000000000000000000001745 171.0
TLS2_k127_2844497_34 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000649 175.0
TLS2_k127_2844497_35 alpha beta - - - 0.0000000000000000000000000000000000000000295 171.0
TLS2_k127_2844497_36 Belongs to the peptidase S26 family - - - 0.000000000000000000000000000000000000438 144.0
TLS2_k127_2844497_37 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000007071 146.0
TLS2_k127_2844497_38 PFAM Cell wall assembly cell proliferation coordinating protein, KNR4-like - - - 0.0000000000000000000000000000000002037 138.0
TLS2_k127_2844497_39 MerR, DNA binding K08365,K19591 - - 0.000000000000000000000000000000002865 143.0
TLS2_k127_2844497_4 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 566.0
TLS2_k127_2844497_40 Cupin domain - - - 0.000000000000000000000000000000009333 132.0
TLS2_k127_2844497_41 - - - - 0.0000000000000000000000000000001835 141.0
TLS2_k127_2844497_44 bacterial-type flagellum organization K02411 - - 0.000000000000000000000000003397 122.0
TLS2_k127_2844497_45 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000000005289 111.0
TLS2_k127_2844497_46 Transposase - - - 0.000000000000000000000004918 109.0
TLS2_k127_2844497_47 Sh3 type 3 domain protein - - - 0.0000000000000000000001025 115.0
TLS2_k127_2844497_48 PAN domain - - - 0.000000000000000000003023 101.0
TLS2_k127_2844497_49 Cytotoxic - - - 0.0000000000000000007191 102.0
TLS2_k127_2844497_5 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 526.0
TLS2_k127_2844497_51 - K16214 - 2.7.1.176 0.000000000000000001624 102.0
TLS2_k127_2844497_52 - - - - 0.000000000000003679 86.0
TLS2_k127_2844497_53 Conserved Protein - - - 0.000000313 56.0
TLS2_k127_2844497_6 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 527.0
TLS2_k127_2844497_7 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 532.0
TLS2_k127_2844497_8 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 521.0
TLS2_k127_2844497_9 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 504.0
TLS2_k127_2850168_0 Lantibiotic biosynthesis dehydratase C-term K20483 - - 1.825e-290 927.0
TLS2_k127_2850168_1 TonB dependent receptor K02014 - - 1.02e-270 860.0
TLS2_k127_2850168_10 Belongs to the Orn Lys Arg decarboxylase class-II family K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 477.0
TLS2_k127_2850168_11 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 383.0
TLS2_k127_2850168_12 Deoxycytidylate deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 383.0
TLS2_k127_2850168_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 349.0
TLS2_k127_2850168_14 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 331.0
TLS2_k127_2850168_15 Lanthionine synthetase C-like protein K20484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000194 266.0
TLS2_k127_2850168_17 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000003626 222.0
TLS2_k127_2850168_18 - - - - 0.000000000000000000000000000000000000000000000000007788 190.0
TLS2_k127_2850168_19 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000001021 179.0
TLS2_k127_2850168_2 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 5.535e-225 705.0
TLS2_k127_2850168_20 - - - - 0.0000000000000000000000000000000000000000000000006878 185.0
TLS2_k127_2850168_21 Bacterial extracellular solute-binding protein K17321 - - 0.00000000000000000000000000000000001043 136.0
TLS2_k127_2850168_22 - - - - 0.0000000000000000000000000000001653 137.0
TLS2_k127_2850168_23 Archease protein family (MTH1598/TM1083) - - - 0.0000000001879 67.0
TLS2_k127_2850168_26 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000007512 55.0
TLS2_k127_2850168_29 Lantibiotic biosynthesis dehydratase C-term K20483 - - 0.000047 50.0
TLS2_k127_2850168_3 Iron-sulfur cluster-binding domain - - - 2.799e-218 683.0
TLS2_k127_2850168_4 Iron-sulfur cluster-binding domain - - - 9.247e-216 676.0
TLS2_k127_2850168_5 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 588.0
TLS2_k127_2850168_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 599.0
TLS2_k127_2850168_7 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 519.0
TLS2_k127_2850168_8 PFAM Peptidase S10, serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 510.0
TLS2_k127_2850168_9 adenosine deaminase K01488,K21053 - 3.5.4.2,3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 482.0
TLS2_k127_2868440_0 DEAD/H associated K03724 - - 0.0 2171.0
TLS2_k127_2868440_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1355.0
TLS2_k127_2868440_10 Belongs to the SEDS family K03588 - - 4.424e-204 644.0
TLS2_k127_2868440_11 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 5.968e-198 623.0
TLS2_k127_2868440_12 Tetratricopeptide repeats - - - 1.645e-197 630.0
TLS2_k127_2868440_13 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 593.0
TLS2_k127_2868440_14 Dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 600.0
TLS2_k127_2868440_15 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 507.0
TLS2_k127_2868440_16 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 479.0
TLS2_k127_2868440_17 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 444.0
TLS2_k127_2868440_18 response regulator K02282,K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 424.0
TLS2_k127_2868440_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 440.0
TLS2_k127_2868440_2 ABC-2 family transporter protein K01992 - - 0.0 1163.0
TLS2_k127_2868440_20 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 431.0
TLS2_k127_2868440_21 PFAM MscS Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 396.0
TLS2_k127_2868440_22 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 384.0
TLS2_k127_2868440_23 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 364.0
TLS2_k127_2868440_24 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 343.0
TLS2_k127_2868440_25 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 319.0
TLS2_k127_2868440_26 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000005918 226.0
TLS2_k127_2868440_28 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000525 205.0
TLS2_k127_2868440_29 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000002285 194.0
TLS2_k127_2868440_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K15792 - 6.3.2.10,6.3.2.13 0.0 1074.0
TLS2_k127_2868440_30 Fic/DOC family - - - 0.00000000000000000000000000000000000000000004033 170.0
TLS2_k127_2868440_31 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000005757 179.0
TLS2_k127_2868440_32 amine dehydrogenase activity - - - 0.00000000000000000000000000000000002703 153.0
TLS2_k127_2868440_33 - - - - 0.0000000000000000000000000000000000716 134.0
TLS2_k127_2868440_34 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000003081 129.0
TLS2_k127_2868440_35 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000000000001172 106.0
TLS2_k127_2868440_39 Transposase - - - 0.00003569 48.0
TLS2_k127_2868440_4 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1053.0
TLS2_k127_2868440_40 histone H2A K63-linked ubiquitination K07169,K11894 - - 0.00008883 52.0
TLS2_k127_2868440_5 Molecular chaperone. Has ATPase activity K04079 - - 5.4e-301 947.0
TLS2_k127_2868440_6 penicillin-binding protein K03587 - 3.4.16.4 2.707e-285 891.0
TLS2_k127_2868440_7 Peptidase S46 - - - 1.701e-278 875.0
TLS2_k127_2868440_8 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 4.288e-232 727.0
TLS2_k127_2868440_9 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.527e-207 649.0
TLS2_k127_2907434_0 PFAM ATP-binding region, ATPase domain protein - - - 0.0 1289.0
TLS2_k127_2907434_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 2.47e-254 788.0
TLS2_k127_2907434_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 9.018e-213 672.0
TLS2_k127_2907434_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.663e-211 668.0
TLS2_k127_2907434_5 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000063 134.0
TLS2_k127_2907434_6 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000007594 121.0
TLS2_k127_2994563_0 - - - - 1.242e-267 862.0
TLS2_k127_2994563_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.459e-260 814.0
TLS2_k127_2994563_10 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 402.0
TLS2_k127_2994563_11 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 381.0
TLS2_k127_2994563_12 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 385.0
TLS2_k127_2994563_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 306.0
TLS2_k127_2994563_14 PFAM MscS Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 315.0
TLS2_k127_2994563_15 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002518 289.0
TLS2_k127_2994563_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 282.0
TLS2_k127_2994563_17 Domain of unknown function (DUF4215) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005784 265.0
TLS2_k127_2994563_18 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000008363 217.0
TLS2_k127_2994563_19 Putative ATP-dependant zinc protease - - - 0.0000000000000000000000000000000000000000001476 180.0
TLS2_k127_2994563_2 Belongs to the peptidase S1B family - - - 5.85e-229 728.0
TLS2_k127_2994563_20 - - - - 0.000000000000000000000000000000000003578 138.0
TLS2_k127_2994563_21 Transposase IS66 family K07484 - - 0.00000000000000000000001492 104.0
TLS2_k127_2994563_22 - - - - 0.00000000000000000003145 91.0
TLS2_k127_2994563_23 AAA ATPase domain - - - 0.00000000000000003315 85.0
TLS2_k127_2994563_24 COG3436 Transposase and inactivated derivatives K07484 - - 0.0000000000000001869 85.0
TLS2_k127_2994563_25 TIGRFAM DNA binding domain - - - 0.0000000000008578 71.0
TLS2_k127_2994563_26 Transposase ISVa5 (IS66-family - - - 0.00002545 50.0
TLS2_k127_2994563_27 Helix-turn-helix domain K07483 - - 0.0004888 47.0
TLS2_k127_2994563_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 1.475e-212 684.0
TLS2_k127_2994563_4 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 6.708e-201 644.0
TLS2_k127_2994563_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 615.0
TLS2_k127_2994563_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 542.0
TLS2_k127_2994563_7 COG0189 Glutathione synthase Ribosomal protein S6 modification K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 479.0
TLS2_k127_2994563_8 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 460.0
TLS2_k127_2994563_9 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 420.0
TLS2_k127_3013108_0 AMP-binding enzyme K00666 - - 2.799e-291 937.0
TLS2_k127_3013108_1 PFAM Archaeal ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 536.0
TLS2_k127_3013108_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 507.0
TLS2_k127_3013108_3 cytochrome P450 - - - 0.00000000000000000000000000000000000000000332 172.0
TLS2_k127_3013108_4 transcription factor jumonji K19219 - - 0.0000000000000000000000000000000000000005928 168.0
TLS2_k127_3013108_5 trans-aconitate 2-methyltransferase activity K00598,K02169 - 2.1.1.144,2.1.1.197 0.00000000000000000000000496 112.0
TLS2_k127_3013108_6 MbtH-like protein K05375,K09190 - - 0.0000000000000000000001457 100.0
TLS2_k127_3013779_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1120.0
TLS2_k127_3013779_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1050.0
TLS2_k127_3013779_10 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 536.0
TLS2_k127_3013779_11 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 480.0
TLS2_k127_3013779_12 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 474.0
TLS2_k127_3013779_13 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 437.0
TLS2_k127_3013779_14 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 413.0
TLS2_k127_3013779_15 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 404.0
TLS2_k127_3013779_16 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 410.0
TLS2_k127_3013779_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 392.0
TLS2_k127_3013779_18 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 391.0
TLS2_k127_3013779_19 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 383.0
TLS2_k127_3013779_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.06e-294 915.0
TLS2_k127_3013779_20 succinate dehydrogenase K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 367.0
TLS2_k127_3013779_21 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 354.0
TLS2_k127_3013779_22 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 372.0
TLS2_k127_3013779_23 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 341.0
TLS2_k127_3013779_24 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 348.0
TLS2_k127_3013779_25 Protein of unknown function (DUF3419) K13622 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 332.0
TLS2_k127_3013779_26 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 321.0
TLS2_k127_3013779_27 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 329.0
TLS2_k127_3013779_28 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 312.0
TLS2_k127_3013779_29 Transcriptional regulators of sugar metabolism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
TLS2_k127_3013779_3 beta-galactosidase K12308 - 3.2.1.23 1.474e-291 909.0
TLS2_k127_3013779_30 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002769 286.0
TLS2_k127_3013779_31 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004592 275.0
TLS2_k127_3013779_32 Iron-containing redox enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000583 278.0
TLS2_k127_3013779_33 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000004952 222.0
TLS2_k127_3013779_34 Exonuclease K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000003953 208.0
TLS2_k127_3013779_35 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000789 205.0
TLS2_k127_3013779_36 - - - - 0.000000000000000000000000000000000000000000000000001857 192.0
TLS2_k127_3013779_37 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000001191 195.0
TLS2_k127_3013779_38 transcriptional regulator K07734 - - 0.0000000000000000000000000000000000000000001033 169.0
TLS2_k127_3013779_39 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000001441 147.0
TLS2_k127_3013779_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.905e-287 891.0
TLS2_k127_3013779_40 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000000000000000004301 139.0
TLS2_k127_3013779_41 rRNA processing K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000005066 132.0
TLS2_k127_3013779_42 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000000005677 129.0
TLS2_k127_3013779_43 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000196 114.0
TLS2_k127_3013779_45 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.00000000000001774 80.0
TLS2_k127_3013779_46 membrane protein domain - - - 0.000000009953 65.0
TLS2_k127_3013779_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 5.071e-230 720.0
TLS2_k127_3013779_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 9.378e-211 669.0
TLS2_k127_3013779_7 peptidoglycan biosynthetic process K07121 - - 1.382e-210 689.0
TLS2_k127_3013779_8 Translation-initiation factor 2 K02519 - - 5.052e-205 679.0
TLS2_k127_3013779_9 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 537.0
TLS2_k127_3096640_0 CarboxypepD_reg-like domain - - - 0.0 1344.0
TLS2_k127_3096640_1 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.0 1174.0
TLS2_k127_3096640_10 Cysteine-rich secretory protein family - - - 2.766e-194 621.0
TLS2_k127_3096640_100 23S rRNA-intervening sequence protein - - - 0.00008272 52.0
TLS2_k127_3096640_101 PFAM CBS domain K03281 - - 0.0001185 53.0
TLS2_k127_3096640_102 Rhodopirellula transposase DDE domain - - - 0.0006817 46.0
TLS2_k127_3096640_103 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 - 0.0007715 52.0
TLS2_k127_3096640_11 Alcohol dehydrogenase GroES-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 617.0
TLS2_k127_3096640_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 602.0
TLS2_k127_3096640_13 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 582.0
TLS2_k127_3096640_14 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 582.0
TLS2_k127_3096640_15 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 563.0
TLS2_k127_3096640_16 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 566.0
TLS2_k127_3096640_17 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 557.0
TLS2_k127_3096640_18 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 541.0
TLS2_k127_3096640_19 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 543.0
TLS2_k127_3096640_2 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.0 1160.0
TLS2_k127_3096640_20 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 525.0
TLS2_k127_3096640_21 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 531.0
TLS2_k127_3096640_22 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 498.0
TLS2_k127_3096640_23 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 487.0
TLS2_k127_3096640_24 Belongs to the class-I aminoacyl-tRNA synthetase family K01885,K01894 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 479.0
TLS2_k127_3096640_25 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 480.0
TLS2_k127_3096640_26 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 481.0
TLS2_k127_3096640_27 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 452.0
TLS2_k127_3096640_28 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 424.0
TLS2_k127_3096640_29 SusD family K21572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 415.0
TLS2_k127_3096640_3 PHP domain protein - - - 0.0 1090.0
TLS2_k127_3096640_30 Bacterial Ig-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 435.0
TLS2_k127_3096640_31 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 401.0
TLS2_k127_3096640_32 UbiE COQ5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 387.0
TLS2_k127_3096640_33 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 383.0
TLS2_k127_3096640_34 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 389.0
TLS2_k127_3096640_35 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 363.0
TLS2_k127_3096640_36 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 362.0
TLS2_k127_3096640_37 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 368.0
TLS2_k127_3096640_38 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 344.0
TLS2_k127_3096640_39 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 318.0
TLS2_k127_3096640_4 Peptidase inhibitor I9 K20754 - 3.4.21.111 1.004e-290 918.0
TLS2_k127_3096640_40 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 319.0
TLS2_k127_3096640_42 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 305.0
TLS2_k127_3096640_43 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 308.0
TLS2_k127_3096640_44 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002036 274.0
TLS2_k127_3096640_45 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001049 262.0
TLS2_k127_3096640_46 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006446 276.0
TLS2_k127_3096640_47 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001656 256.0
TLS2_k127_3096640_48 Sigma-70, region 4 K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002038 257.0
TLS2_k127_3096640_49 photoreceptor activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001656 265.0
TLS2_k127_3096640_5 protein kinase activity - - - 5.014e-270 838.0
TLS2_k127_3096640_50 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000479 261.0
TLS2_k127_3096640_51 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004527 271.0
TLS2_k127_3096640_52 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003679 259.0
TLS2_k127_3096640_53 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004169 241.0
TLS2_k127_3096640_54 Belongs to the MIP aquaporin (TC 1.A.8) family K09874 GO:0003674,GO:0005215,GO:0005372,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006833,GO:0008150,GO:0015250,GO:0015267,GO:0015318,GO:0015840,GO:0016020,GO:0016021,GO:0019755,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042044,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000007674 247.0
TLS2_k127_3096640_55 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000001471 242.0
TLS2_k127_3096640_56 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000019 205.0
TLS2_k127_3096640_57 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000000000000006441 202.0
TLS2_k127_3096640_58 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000003309 202.0
TLS2_k127_3096640_59 COG3047 Outer membrane protein W - - - 0.00000000000000000000000000000000000000000000000002547 196.0
TLS2_k127_3096640_6 Protein kinase domain - - - 1.277e-253 822.0
TLS2_k127_3096640_60 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000005181 186.0
TLS2_k127_3096640_61 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000001325 186.0
TLS2_k127_3096640_63 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000003949 176.0
TLS2_k127_3096640_64 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000002174 186.0
TLS2_k127_3096640_66 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000002182 175.0
TLS2_k127_3096640_68 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000007861 149.0
TLS2_k127_3096640_69 peptidyl-arginine hydroxylation - - - 0.0000000000000000000000000000000000000009763 161.0
TLS2_k127_3096640_7 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 1.073e-208 661.0
TLS2_k127_3096640_70 TPR repeat - - - 0.000000000000000000000000000000000000002004 164.0
TLS2_k127_3096640_71 protein conserved in bacteria - - - 0.0000000000000000000000000000000000001148 154.0
TLS2_k127_3096640_72 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000001903 151.0
TLS2_k127_3096640_73 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000005609 148.0
TLS2_k127_3096640_74 YCII-related domain K09780 - - 0.000000000000000000000000000000003708 131.0
TLS2_k127_3096640_75 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000171 134.0
TLS2_k127_3096640_76 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000001503 124.0
TLS2_k127_3096640_77 Virulence factor BrkB K07058 - - 0.00000000000000000000000000009654 132.0
TLS2_k127_3096640_78 YhhN family - - - 0.000000000000000000000000001137 120.0
TLS2_k127_3096640_79 radical SAM domain protein - - - 0.000000000000000000000001852 117.0
TLS2_k127_3096640_8 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 4.052e-207 658.0
TLS2_k127_3096640_81 - - - - 0.0000000000000000000000767 101.0
TLS2_k127_3096640_82 - - - - 0.0000000000000000000004772 107.0
TLS2_k127_3096640_83 PFAM regulatory protein, ArsR K03892 - - 0.000000000000000000002359 102.0
TLS2_k127_3096640_85 - - - - 0.0000000000002775 80.0
TLS2_k127_3096640_86 SnoaL-like polyketide cyclase - - - 0.0000000000004073 79.0
TLS2_k127_3096640_88 MerC mercury resistance protein - - - 0.000000000001111 74.0
TLS2_k127_3096640_89 - - - - 0.000000000002514 78.0
TLS2_k127_3096640_91 DNA-templated transcription, initiation - - - 0.0000000000279 77.0
TLS2_k127_3096640_94 Chorismate mutase type II K04782 - 4.2.99.21 0.00000003371 58.0
TLS2_k127_3096640_95 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000005093 59.0
TLS2_k127_3096640_96 Domain of unknown function (DUF4360) - - - 0.0000002552 62.0
TLS2_k127_3096640_97 Novel toxin 16 - - - 0.000001075 57.0
TLS2_k127_3096640_99 Domain of unknown function (DUF4349) - - - 0.00001627 57.0
TLS2_k127_3118179_0 ATPase involved in DNA repair - - - 0.0 2044.0
TLS2_k127_3118179_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1019.0
TLS2_k127_3118179_10 PQQ enzyme repeat K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 479.0
TLS2_k127_3118179_11 Phage tail sheath C-terminal domain K06907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 456.0
TLS2_k127_3118179_12 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 425.0
TLS2_k127_3118179_13 Phage late control gene D protein (GPD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 413.0
TLS2_k127_3118179_14 Sigma-54 interaction domain K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 409.0
TLS2_k127_3118179_15 EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 380.0
TLS2_k127_3118179_16 PFAM sigma-54 factor interaction domain-containing protein K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 398.0
TLS2_k127_3118179_17 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 343.0
TLS2_k127_3118179_18 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 352.0
TLS2_k127_3118179_19 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 285.0
TLS2_k127_3118179_2 Transcriptional regulator - - - 5.143e-233 749.0
TLS2_k127_3118179_20 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002198 269.0
TLS2_k127_3118179_21 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000938 255.0
TLS2_k127_3118179_24 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000002306 222.0
TLS2_k127_3118179_26 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000003215 209.0
TLS2_k127_3118179_27 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000009043 207.0
TLS2_k127_3118179_28 VTC domain - - - 0.0000000000000000000000000000000000000000000000000000001086 205.0
TLS2_k127_3118179_29 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000000003215 203.0
TLS2_k127_3118179_3 Band 7 protein K07192 - - 1.644e-228 730.0
TLS2_k127_3118179_30 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000001853 200.0
TLS2_k127_3118179_31 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000000001139 184.0
TLS2_k127_3118179_32 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000003232 183.0
TLS2_k127_3118179_33 LysM domain - - - 0.00000000000000000000000000000000000000000000001864 195.0
TLS2_k127_3118179_34 - - - - 0.0000000000000000000000000000000000000000000001135 176.0
TLS2_k127_3118179_37 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000004439 162.0
TLS2_k127_3118179_38 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000000000000000004906 158.0
TLS2_k127_3118179_39 Phage tail protein (Tail_P2_I) - - - 0.000000000000000000000000000000000000005436 151.0
TLS2_k127_3118179_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 3.254e-222 707.0
TLS2_k127_3118179_40 - - - - 0.00000000000000000000000000000000000001129 154.0
TLS2_k127_3118179_41 - K06903 - - 0.000000000000000000000000000000000009334 145.0
TLS2_k127_3118179_42 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000001773 128.0
TLS2_k127_3118179_44 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000001007 110.0
TLS2_k127_3118179_46 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000001267 93.0
TLS2_k127_3118179_48 - - - - 0.000000000000000000417 91.0
TLS2_k127_3118179_49 Tetratricopeptide repeat - - - 0.00000000000000001738 95.0
TLS2_k127_3118179_5 Baseplate J-like protein - - - 1.48e-210 688.0
TLS2_k127_3118179_50 - - - - 0.000000000009815 76.0
TLS2_k127_3118179_52 PFAM Peptidoglycan-binding - - - 0.0000008642 63.0
TLS2_k127_3118179_53 Major facilitator Superfamily - - - 0.00006046 46.0
TLS2_k127_3118179_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 5.285e-207 657.0
TLS2_k127_3118179_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 582.0
TLS2_k127_3118179_8 Multicopper oxidase K00368,K22349 - 1.16.3.3,1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 537.0
TLS2_k127_3118179_9 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 499.0
TLS2_k127_3211916_0 Tetratricopeptide repeat - - - 0.0 1354.0
TLS2_k127_3211916_1 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 458.0
TLS2_k127_3211916_2 FHA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 396.0
TLS2_k127_3211916_3 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000002509 200.0
TLS2_k127_3211916_4 GTP-binding protein K06207 - - 0.00000000000001008 75.0
TLS2_k127_3251303_0 ABC transporter K06020 - 3.6.3.25 7.737e-306 946.0
TLS2_k127_3251303_1 Radical SAM superfamily K06139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 601.0
TLS2_k127_3251303_10 Putative small multi-drug export protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 318.0
TLS2_k127_3251303_11 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 319.0
TLS2_k127_3251303_12 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 310.0
TLS2_k127_3251303_13 DnaJ C terminal domain K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001017 278.0
TLS2_k127_3251303_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001594 264.0
TLS2_k127_3251303_16 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003042 268.0
TLS2_k127_3251303_17 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000001983 234.0
TLS2_k127_3251303_18 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000003101 183.0
TLS2_k127_3251303_19 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000006752 165.0
TLS2_k127_3251303_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 444.0
TLS2_k127_3251303_20 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000091 117.0
TLS2_k127_3251303_21 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000002298 114.0
TLS2_k127_3251303_22 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000002361 128.0
TLS2_k127_3251303_23 - - - - 0.0000000000000000000000611 108.0
TLS2_k127_3251303_26 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000005406 80.0
TLS2_k127_3251303_28 amine dehydrogenase activity - - - 0.0001589 49.0
TLS2_k127_3251303_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 467.0
TLS2_k127_3251303_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009342 442.0
TLS2_k127_3251303_5 PFAM Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 386.0
TLS2_k127_3251303_6 Pfam:Gp37_Gp68 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 391.0
TLS2_k127_3251303_7 Protoglobin - GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0020037,GO:0023014,GO:0023052,GO:0035556,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046906,GO:0046983,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0140096,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 371.0
TLS2_k127_3251303_8 zinc metalloprotease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 330.0
TLS2_k127_3251303_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 334.0
TLS2_k127_3269270_0 acyl-CoA dehydrogenase K09456,K20035 - - 7.571e-308 952.0
TLS2_k127_3269270_1 Peptidase family M3 K01392 - 3.4.24.15 4.845e-303 942.0
TLS2_k127_3269270_10 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 395.0
TLS2_k127_3269270_11 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 377.0
TLS2_k127_3269270_12 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 346.0
TLS2_k127_3269270_13 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 359.0
TLS2_k127_3269270_14 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 314.0
TLS2_k127_3269270_16 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001044 256.0
TLS2_k127_3269270_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000003906 231.0
TLS2_k127_3269270_18 COG0695 Glutaredoxin and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000747 216.0
TLS2_k127_3269270_19 PKD domain - - - 0.000000000000000000000000000000000000000000000000000003941 215.0
TLS2_k127_3269270_2 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.724e-281 871.0
TLS2_k127_3269270_20 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000004853 185.0
TLS2_k127_3269270_21 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.00000000000000000000000000000000000000009954 159.0
TLS2_k127_3269270_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 3.475e-260 807.0
TLS2_k127_3269270_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 7.773e-209 657.0
TLS2_k127_3269270_5 Protein of unknown function (DUF1156) K07445 - - 1.947e-196 635.0
TLS2_k127_3269270_6 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 9.137e-195 612.0
TLS2_k127_3269270_7 Metal dependent phosphohydrolases with conserved 'HD' motif. K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 511.0
TLS2_k127_3269270_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 539.0
TLS2_k127_3269270_9 Bacterial extracellular solute-binding protein K10108,K15770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 473.0
TLS2_k127_3293868_0 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 3.361e-225 725.0
TLS2_k127_3293868_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 584.0
TLS2_k127_3293868_2 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 503.0
TLS2_k127_3293868_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 398.0
TLS2_k127_3293868_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 302.0
TLS2_k127_3293868_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000001217 216.0
TLS2_k127_3293868_6 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000005483 203.0
TLS2_k127_3293868_8 PFAM Radical SAM domain protein - - - 0.000003686 51.0
TLS2_k127_3293868_9 amine dehydrogenase activity - - - 0.0000076 51.0
TLS2_k127_3317979_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 552.0
TLS2_k127_3317979_1 Thioredoxin - - - 0.000000000000000000000000000004209 133.0
TLS2_k127_3317979_2 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000004634 125.0
TLS2_k127_3317979_3 - - - - 0.00000000000000000000000003338 117.0
TLS2_k127_3317979_4 cellulase activity - - - 0.000000000000002923 89.0
TLS2_k127_3317979_5 - - - - 0.000001846 60.0
TLS2_k127_3339853_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1393.0
TLS2_k127_3339853_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0 1380.0
TLS2_k127_3339853_10 Radical SAM - - - 1.742e-227 713.0
TLS2_k127_3339853_11 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 2.399e-227 712.0
TLS2_k127_3339853_12 Belongs to the glycosyl hydrolase 32 family K01193 - 3.2.1.26 1.083e-198 655.0
TLS2_k127_3339853_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 537.0
TLS2_k127_3339853_14 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 521.0
TLS2_k127_3339853_15 COG0277 FAD FMN-containing dehydrogenases K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 453.0
TLS2_k127_3339853_16 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 457.0
TLS2_k127_3339853_17 Sulfotransferase domain K01014 - 2.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 429.0
TLS2_k127_3339853_18 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 419.0
TLS2_k127_3339853_19 Sulfotransferase domain K01014 - 2.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 383.0
TLS2_k127_3339853_2 Sulfatase K01133 - 3.1.6.6 0.0 1156.0
TLS2_k127_3339853_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 382.0
TLS2_k127_3339853_21 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 385.0
TLS2_k127_3339853_22 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 359.0
TLS2_k127_3339853_23 TIGRFAM cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 342.0
TLS2_k127_3339853_24 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 347.0
TLS2_k127_3339853_25 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 357.0
TLS2_k127_3339853_26 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 317.0
TLS2_k127_3339853_27 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 306.0
TLS2_k127_3339853_28 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000007738 249.0
TLS2_k127_3339853_29 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000007486 246.0
TLS2_k127_3339853_3 Signal transduction histidine kinase - - - 0.0 1034.0
TLS2_k127_3339853_30 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006577 257.0
TLS2_k127_3339853_31 Ribosomal small subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000009949 236.0
TLS2_k127_3339853_32 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000004713 219.0
TLS2_k127_3339853_33 cellulose binding - - - 0.000000000000000000000000000000000000000000000000009136 196.0
TLS2_k127_3339853_34 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000003103 191.0
TLS2_k127_3339853_35 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000903 188.0
TLS2_k127_3339853_36 TIGRFAM YD repeat protein - - - 0.000000000000000000000000000000000000001592 170.0
TLS2_k127_3339853_37 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000055 136.0
TLS2_k127_3339853_38 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000001147 113.0
TLS2_k127_3339853_39 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000001707 111.0
TLS2_k127_3339853_4 serine threonine protein kinase K12132 - 2.7.11.1 1.18e-321 1035.0
TLS2_k127_3339853_41 - - - - 0.00000000000000000005289 101.0
TLS2_k127_3339853_42 phage tail tape measure protein - - - 0.0000000000000001339 95.0
TLS2_k127_3339853_43 PFAM blue (type 1) copper domain protein - - - 0.0000002808 61.0
TLS2_k127_3339853_44 Cytochrome P460 - - - 0.0000007232 58.0
TLS2_k127_3339853_45 Psort location Cytoplasmic, score 8.96 - - - 0.000002118 58.0
TLS2_k127_3339853_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 1.588e-266 846.0
TLS2_k127_3339853_6 alpha-glucan phosphorylase K00688 - 2.4.1.1 1.211e-250 801.0
TLS2_k127_3339853_7 PAS sensor protein K13243 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008081,GO:0008144,GO:0008150,GO:0009628,GO:0016787,GO:0016788,GO:0019825,GO:0019826,GO:0020037,GO:0036094,GO:0042578,GO:0043167,GO:0043169,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0070482,GO:0071111,GO:0097159,GO:1901363 3.1.4.52 2.799e-244 793.0
TLS2_k127_3339853_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 1.997e-238 751.0
TLS2_k127_3339853_9 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 8.4e-235 734.0
TLS2_k127_3386960_0 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.0 1283.0
TLS2_k127_3386960_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1041.0
TLS2_k127_3386960_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 333.0
TLS2_k127_3386960_11 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 303.0
TLS2_k127_3386960_12 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 283.0
TLS2_k127_3386960_13 anaerobic respiration K02568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002241 257.0
TLS2_k127_3386960_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003457 250.0
TLS2_k127_3386960_15 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003636 244.0
TLS2_k127_3386960_16 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000001318 244.0
TLS2_k127_3386960_17 - - - - 0.00000000000000000000000000000000000000000000000000007208 198.0
TLS2_k127_3386960_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 7.659e-260 814.0
TLS2_k127_3386960_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000005208 162.0
TLS2_k127_3386960_21 Domain of unknown function (DUF3817) - - - 0.0000000000000000000000000000000000000001029 152.0
TLS2_k127_3386960_24 - - - - 0.0000000000000001246 85.0
TLS2_k127_3386960_3 Domain of unknown function (DUF4157) - - - 2.002e-258 844.0
TLS2_k127_3386960_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 2.944e-252 784.0
TLS2_k127_3386960_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.029e-229 722.0
TLS2_k127_3386960_6 Polysulphide reductase, NrfD K00185 - - 1.021e-216 678.0
TLS2_k127_3386960_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 552.0
TLS2_k127_3386960_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 481.0
TLS2_k127_3386960_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 386.0
TLS2_k127_3475032_0 Protein kinase; unclassified specificity. K12132 - 2.7.11.1 0.0 1217.0
TLS2_k127_3475032_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 3.206e-304 953.0
TLS2_k127_3475032_10 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 295.0
TLS2_k127_3475032_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005505 270.0
TLS2_k127_3475032_12 Sterol carrier protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009811 254.0
TLS2_k127_3475032_15 cytochrome c nitrite reductase K15876 - - 0.000000000000000000000000000000000000000000000000000000000008714 215.0
TLS2_k127_3475032_16 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ - - - 0.00000000000000000000000000000000000000000000000000000000008937 225.0
TLS2_k127_3475032_17 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000003595 215.0
TLS2_k127_3475032_18 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000003071 198.0
TLS2_k127_3475032_2 signal peptide peptidase SppA, 36K type K04773 - - 2.918e-285 903.0
TLS2_k127_3475032_21 methyltransferase - - - 0.0000000000000000000000000000000000000003143 169.0
TLS2_k127_3475032_22 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000001816 113.0
TLS2_k127_3475032_23 PAN domain - - - 0.0000000000003222 83.0
TLS2_k127_3475032_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 1.537e-196 628.0
TLS2_k127_3475032_4 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 603.0
TLS2_k127_3475032_5 PFAM Sodium sulphate symporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 556.0
TLS2_k127_3475032_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 534.0
TLS2_k127_3475032_7 Belongs to the arginase family K01480,K18459 - 3.5.3.11,3.5.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 424.0
TLS2_k127_3475032_8 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 415.0
TLS2_k127_3475032_9 dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 352.0
TLS2_k127_3479856_0 Tetratricopeptide repeat - - - 0.0 4651.0
TLS2_k127_3479856_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 6.522e-284 877.0
TLS2_k127_3479856_10 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 386.0
TLS2_k127_3479856_11 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 355.0
TLS2_k127_3479856_12 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 370.0
TLS2_k127_3479856_14 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 336.0
TLS2_k127_3479856_15 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 308.0
TLS2_k127_3479856_16 Involved in chromosome partitioning - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 315.0
TLS2_k127_3479856_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 312.0
TLS2_k127_3479856_18 Peptidase C26 K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001549 281.0
TLS2_k127_3479856_19 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001082 283.0
TLS2_k127_3479856_2 Glycosyl hydrolases family 15 - - - 2.755e-282 887.0
TLS2_k127_3479856_20 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004848 268.0
TLS2_k127_3479856_21 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005773 260.0
TLS2_k127_3479856_22 Belongs to the UPF0754 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001347 258.0
TLS2_k127_3479856_23 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004247 259.0
TLS2_k127_3479856_24 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000002848 238.0
TLS2_k127_3479856_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000005288 228.0
TLS2_k127_3479856_26 - - - - 0.0000000000000000000000000000000000000000000000000000001459 202.0
TLS2_k127_3479856_27 Protein of unknown function (DUF3696) - - - 0.00000000000000000000000000000000000000000000000001243 195.0
TLS2_k127_3479856_28 - - - - 0.00000000000000000000000000000000000002324 162.0
TLS2_k127_3479856_29 Thioesterase K07107 - - 0.00000000000000000000000000000000005287 139.0
TLS2_k127_3479856_3 Radical SAM - - - 1.963e-249 779.0
TLS2_k127_3479856_31 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000009735 117.0
TLS2_k127_3479856_32 - - - - 0.000000000000000000002518 101.0
TLS2_k127_3479856_33 HEPN domain - - - 0.0000000000000001084 87.0
TLS2_k127_3479856_35 PKD domain containing protein - - - 0.000000000000002524 91.0
TLS2_k127_3479856_36 protein adenylyltransferase activity K17277 GO:0000166,GO:0003008,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006952,GO:0007600,GO:0007601,GO:0007610,GO:0007632,GO:0008081,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009966,GO:0009987,GO:0010646,GO:0012505,GO:0015696,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0023051,GO:0030176,GO:0030544,GO:0030554,GO:0031072,GO:0031224,GO:0031227,GO:0031967,GO:0031975,GO:0031984,GO:0032501,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034260,GO:0034976,GO:0035639,GO:0036094,GO:0036211,GO:0042175,GO:0042578,GO:0042742,GO:0042802,GO:0042803,GO:0043086,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044601,GO:0044602,GO:0044603,GO:0045117,GO:0046983,GO:0048519,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050829,GO:0050877,GO:0050896,GO:0050906,GO:0050908,GO:0050953,GO:0050962,GO:0051087,GO:0051179,GO:0051234,GO:0051336,GO:0051346,GO:0051606,GO:0051608,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0065009,GO:0070566,GO:0070733,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0080134,GO:0080135,GO:0097159,GO:0097367,GO:0098542,GO:0098827,GO:0140096,GO:1900101,GO:1901265,GO:1901363,GO:1901564,GO:1903894,GO:1905897 - 0.00000000000002837 88.0
TLS2_k127_3479856_39 M6 family metalloprotease domain protein - - - 0.000000000000484 83.0
TLS2_k127_3479856_4 PhoD-like phosphatase K01113 - 3.1.3.1 3.074e-232 737.0
TLS2_k127_3479856_41 metallopeptidase activity K01181,K15531 GO:0005575,GO:0016020 3.2.1.156,3.2.1.8 0.000366 54.0
TLS2_k127_3479856_5 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 539.0
TLS2_k127_3479856_6 Belongs to the cytochrome P450 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 458.0
TLS2_k127_3479856_7 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 426.0
TLS2_k127_3479856_8 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 428.0
TLS2_k127_3479856_9 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 392.0
TLS2_k127_3537112_0 Tex-like protein N-terminal domain K06959 - - 0.0 1182.0
TLS2_k127_3537112_1 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 367.0
TLS2_k127_3537112_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 318.0
TLS2_k127_3537112_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005311 249.0
TLS2_k127_3537112_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004648 230.0
TLS2_k127_3537112_5 ChaC-like protein K07232 - - 0.00000000000000000000000000000000000000000000000000000000685 207.0
TLS2_k127_3537112_6 bacterial-type flagellum organization K02411 - - 0.0000000000000000000000000000000000000000000000000000001427 210.0
TLS2_k127_3537112_7 - - - - 0.000000000000000000000000000000000000000003529 165.0
TLS2_k127_354091_0 Domain of unknown function (DUF4175) - - - 0.0 1058.0
TLS2_k127_354091_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 2.475e-249 790.0
TLS2_k127_354091_2 Peptidase MA superfamily - - - 6.089e-210 704.0
TLS2_k127_354091_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 314.0
TLS2_k127_3684279_0 repeat protein - - - 0.0 3484.0
TLS2_k127_3684279_1 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 481.0
TLS2_k127_3765029_0 50S ribosome-binding GTPase - - - 1.221e-315 997.0
TLS2_k127_3765029_1 - - - - 3.852e-309 985.0
TLS2_k127_3765029_10 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 610.0
TLS2_k127_3765029_11 UvrD-like helicase C-terminal domain K03656,K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 582.0
TLS2_k127_3765029_12 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 559.0
TLS2_k127_3765029_13 DegT/DnrJ/EryC1/StrS aminotransferase family K13010,K19430 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 512.0
TLS2_k127_3765029_14 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 502.0
TLS2_k127_3765029_15 DNA methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 491.0
TLS2_k127_3765029_16 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 482.0
TLS2_k127_3765029_17 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 464.0
TLS2_k127_3765029_18 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 458.0
TLS2_k127_3765029_19 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 449.0
TLS2_k127_3765029_2 Dynamin family - - - 7.97e-295 923.0
TLS2_k127_3765029_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K02022,K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 443.0
TLS2_k127_3765029_21 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 428.0
TLS2_k127_3765029_23 nodulation K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 407.0
TLS2_k127_3765029_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 406.0
TLS2_k127_3765029_25 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 381.0
TLS2_k127_3765029_26 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 362.0
TLS2_k127_3765029_27 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 348.0
TLS2_k127_3765029_29 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 328.0
TLS2_k127_3765029_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 7.904e-289 893.0
TLS2_k127_3765029_30 RNA-DNA hybrid ribonuclease activity K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 321.0
TLS2_k127_3765029_31 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 332.0
TLS2_k127_3765029_32 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 304.0
TLS2_k127_3765029_33 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 296.0
TLS2_k127_3765029_34 Bacterial transferase hexapeptide (six repeats) K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 295.0
TLS2_k127_3765029_35 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001505 264.0
TLS2_k127_3765029_36 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000007731 268.0
TLS2_k127_3765029_37 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000006178 259.0
TLS2_k127_3765029_38 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007232 273.0
TLS2_k127_3765029_39 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003022 256.0
TLS2_k127_3765029_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.405e-236 751.0
TLS2_k127_3765029_40 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004306 258.0
TLS2_k127_3765029_41 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000002682 239.0
TLS2_k127_3765029_42 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009469 235.0
TLS2_k127_3765029_43 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000001325 231.0
TLS2_k127_3765029_45 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000008475 221.0
TLS2_k127_3765029_46 defense response to virus - - - 0.0000000000000000000000000000000000000000000000000000008162 197.0
TLS2_k127_3765029_47 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000000000000000264 196.0
TLS2_k127_3765029_48 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000001266 187.0
TLS2_k127_3765029_49 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000001175 198.0
TLS2_k127_3765029_5 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 8.638e-236 743.0
TLS2_k127_3765029_50 bacterial-type flagellum organization K02411 - - 0.000000000000000000000000000000000000000000005152 178.0
TLS2_k127_3765029_51 sequence-specific DNA binding - - - 0.0000000000000000000000000000000003363 138.0
TLS2_k127_3765029_52 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000009914 135.0
TLS2_k127_3765029_54 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000001693 122.0
TLS2_k127_3765029_55 NUDIX hydrolase - - - 0.0000000000000000000000000001286 125.0
TLS2_k127_3765029_56 - - - - 0.000000000000000000000000000333 133.0
TLS2_k127_3765029_57 - - - - 0.00000000000000000000001508 109.0
TLS2_k127_3765029_58 Glycosyl transferases group 1 - - - 0.000000000000000000004932 109.0
TLS2_k127_3765029_6 zinc-ribbon domain - - - 9.113e-229 760.0
TLS2_k127_3765029_61 methyltransferase - - - 0.00001266 58.0
TLS2_k127_3765029_62 - - - - 0.000158 45.0
TLS2_k127_3765029_63 - - - - 0.0004455 46.0
TLS2_k127_3765029_7 Radical SAM superfamily - - - 1.458e-196 619.0
TLS2_k127_3765029_8 Amidohydrolase family K01466 - 3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 613.0
TLS2_k127_3765029_9 Belongs to the glycosyl hydrolase 35 family K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 627.0
TLS2_k127_3774518_0 FIST N domain - - - 0.0 1427.0
TLS2_k127_3774518_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 1.17e-321 1004.0
TLS2_k127_3774518_10 magnesium chelatase activity K03404,K07114 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 434.0
TLS2_k127_3774518_11 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 424.0
TLS2_k127_3774518_12 AAA domain, putative AbiEii toxin, Type IV TA system K06926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 386.0
TLS2_k127_3774518_13 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 360.0
TLS2_k127_3774518_14 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 334.0
TLS2_k127_3774518_15 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 340.0
TLS2_k127_3774518_16 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 321.0
TLS2_k127_3774518_17 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 308.0
TLS2_k127_3774518_18 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 295.0
TLS2_k127_3774518_19 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002498 303.0
TLS2_k127_3774518_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.371e-319 996.0
TLS2_k127_3774518_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003714 278.0
TLS2_k127_3774518_21 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000003591 240.0
TLS2_k127_3774518_22 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000002716 193.0
TLS2_k127_3774518_23 B-1 B cell differentiation - - - 0.000000000000000000000000000000000000002985 165.0
TLS2_k127_3774518_24 RloB-like protein - - - 0.000000000000000000000000000000815 132.0
TLS2_k127_3774518_25 oxidoreductase activity - - - 0.00000000000000000000003985 115.0
TLS2_k127_3774518_27 PFAM Archaeal ATPase - - - 0.000000000000005707 88.0
TLS2_k127_3774518_28 Trypsin-like peptidase domain - - - 0.00000000000006756 78.0
TLS2_k127_3774518_29 DnaK suppressor protein - - - 0.0000000000004122 82.0
TLS2_k127_3774518_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.719e-313 969.0
TLS2_k127_3774518_30 Polyketide cyclase / dehydrase and lipid transport - - - 0.00002157 56.0
TLS2_k127_3774518_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 7.476e-289 896.0
TLS2_k127_3774518_5 Histidine kinase K13598 - 2.7.13.3 2.211e-229 722.0
TLS2_k127_3774518_6 PFAM Archaeal ATPase - - - 2.381e-218 688.0
TLS2_k127_3774518_7 SMART Integrin alpha beta-propellor repeat protein - - - 3.952e-202 665.0
TLS2_k127_3774518_8 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 524.0
TLS2_k127_3774518_9 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 433.0
TLS2_k127_3785941_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1356.0
TLS2_k127_3785941_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1201.0
TLS2_k127_3785941_10 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 1.04e-230 726.0
TLS2_k127_3785941_11 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 4.173e-224 703.0
TLS2_k127_3785941_12 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 6.601e-201 634.0
TLS2_k127_3785941_13 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 573.0
TLS2_k127_3785941_14 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 562.0
TLS2_k127_3785941_15 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 536.0
TLS2_k127_3785941_16 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 535.0
TLS2_k127_3785941_17 Protein of unknown function (DUF2813) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 528.0
TLS2_k127_3785941_18 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 520.0
TLS2_k127_3785941_19 Binding-protein-dependent transport system inner membrane component K02033,K12369,K13890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 489.0
TLS2_k127_3785941_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - - 0.0 1067.0
TLS2_k127_3785941_20 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 453.0
TLS2_k127_3785941_21 SMART serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 457.0
TLS2_k127_3785941_22 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 442.0
TLS2_k127_3785941_23 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009969 420.0
TLS2_k127_3785941_24 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 362.0
TLS2_k127_3785941_25 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 373.0
TLS2_k127_3785941_26 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 359.0
TLS2_k127_3785941_27 HAMP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 358.0
TLS2_k127_3785941_28 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 345.0
TLS2_k127_3785941_29 heat shock protein binding K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 324.0
TLS2_k127_3785941_3 - - - - 8.032e-312 994.0
TLS2_k127_3785941_30 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 328.0
TLS2_k127_3785941_31 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 328.0
TLS2_k127_3785941_32 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 312.0
TLS2_k127_3785941_33 nitric oxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 296.0
TLS2_k127_3785941_34 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 301.0
TLS2_k127_3785941_35 Alpha/beta hydrolase family K22318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 274.0
TLS2_k127_3785941_36 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001621 266.0
TLS2_k127_3785941_37 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000423 262.0
TLS2_k127_3785941_38 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000003795 245.0
TLS2_k127_3785941_39 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007644 247.0
TLS2_k127_3785941_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - 3.896e-310 962.0
TLS2_k127_3785941_40 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000003604 255.0
TLS2_k127_3785941_41 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000002147 214.0
TLS2_k127_3785941_43 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000000000002906 193.0
TLS2_k127_3785941_44 nitrite reductase [NAD(P)H] activity K05710,K15762,K22360 - - 0.000000000000000000000000000000000000000000001608 166.0
TLS2_k127_3785941_45 Transposase - - - 0.000000000000000000000000000000000000000002748 177.0
TLS2_k127_3785941_46 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000001807 160.0
TLS2_k127_3785941_47 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 0.000000000000000000000000000000000000001298 169.0
TLS2_k127_3785941_48 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000001579 150.0
TLS2_k127_3785941_49 - - - - 0.000000000000000000000000000000000000007639 157.0
TLS2_k127_3785941_5 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.029e-302 933.0
TLS2_k127_3785941_51 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000001326 121.0
TLS2_k127_3785941_52 unsaturated fatty acid biosynthetic process K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000001707 121.0
TLS2_k127_3785941_53 protein kinase activity - - - 0.00000000000000000000002182 116.0
TLS2_k127_3785941_56 cheY-homologous receiver domain - - - 0.000000000000008189 81.0
TLS2_k127_3785941_57 HEPN domain - - - 0.00000000000008479 76.0
TLS2_k127_3785941_58 - - - - 0.0000000000001014 78.0
TLS2_k127_3785941_59 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.00000000002551 68.0
TLS2_k127_3785941_6 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 8.615e-296 925.0
TLS2_k127_3785941_61 signal transduction Histidine kinase - - - 0.000000002436 59.0
TLS2_k127_3785941_7 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 2.537e-286 897.0
TLS2_k127_3785941_8 response regulator K07713 - - 6.387e-241 773.0
TLS2_k127_3785941_9 ERAP1-like C-terminal domain K01263 - 3.4.11.14 9.282e-241 774.0
TLS2_k127_3825491_0 Type III restriction protein res subunit K01153 - 3.1.21.3 0.0 1219.0
TLS2_k127_3825491_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1215.0
TLS2_k127_3825491_10 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 9.108e-216 703.0
TLS2_k127_3825491_11 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.903e-206 655.0
TLS2_k127_3825491_12 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 1.121e-204 649.0
TLS2_k127_3825491_13 Acts as a magnesium transporter K06213 - - 5.97e-200 631.0
TLS2_k127_3825491_14 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 610.0
TLS2_k127_3825491_15 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 617.0
TLS2_k127_3825491_16 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 554.0
TLS2_k127_3825491_17 Bacterial regulatory protein, Fis family K11384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 546.0
TLS2_k127_3825491_18 histone H2A K63-linked ubiquitination K01768,K03529 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 552.0
TLS2_k127_3825491_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 497.0
TLS2_k127_3825491_2 Peptidase M16 - - - 0.0 1181.0
TLS2_k127_3825491_20 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 498.0
TLS2_k127_3825491_21 response regulator K02282,K20971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 475.0
TLS2_k127_3825491_22 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 445.0
TLS2_k127_3825491_23 Flavin containing amine oxidoreductase K02293 - 1.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 456.0
TLS2_k127_3825491_24 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 433.0
TLS2_k127_3825491_25 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 409.0
TLS2_k127_3825491_26 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 402.0
TLS2_k127_3825491_27 HAMP domain K11383 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 411.0
TLS2_k127_3825491_28 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 387.0
TLS2_k127_3825491_29 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 394.0
TLS2_k127_3825491_3 peptidase S8 - - - 3.28e-300 946.0
TLS2_k127_3825491_30 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 386.0
TLS2_k127_3825491_31 cytochrome P450 K15629 - 1.11.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 388.0
TLS2_k127_3825491_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 376.0
TLS2_k127_3825491_33 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 374.0
TLS2_k127_3825491_34 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 384.0
TLS2_k127_3825491_35 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 357.0
TLS2_k127_3825491_36 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 352.0
TLS2_k127_3825491_37 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 345.0
TLS2_k127_3825491_38 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 341.0
TLS2_k127_3825491_39 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 331.0
TLS2_k127_3825491_4 Protein conserved in bacteria K09800 - - 2.244e-277 902.0
TLS2_k127_3825491_40 Monooxygenase fad-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 325.0
TLS2_k127_3825491_41 COG0732 Restriction endonuclease S subunits K01154 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 318.0
TLS2_k127_3825491_42 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 302.0
TLS2_k127_3825491_43 cell redox homeostasis K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 289.0
TLS2_k127_3825491_44 B3/4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005249 275.0
TLS2_k127_3825491_45 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004531 264.0
TLS2_k127_3825491_47 amine dehydrogenase activity K13730 - - 0.0000000000000000000000000000000000000000000000000000000000000000002712 243.0
TLS2_k127_3825491_48 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007444 233.0
TLS2_k127_3825491_49 HEPN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001241 241.0
TLS2_k127_3825491_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 4.067e-271 857.0
TLS2_k127_3825491_50 HEPN domain - - - 0.000000000000000000000000000000000000000000000000000000000000009695 227.0
TLS2_k127_3825491_51 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000001297 229.0
TLS2_k127_3825491_52 - - - - 0.00000000000000000000000000000000000000000000000000000000000001463 221.0
TLS2_k127_3825491_53 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000001087 207.0
TLS2_k127_3825491_54 CBS domain K04767,K07168,K07182 - - 0.0000000000000000000000000000000000000000000000000001634 189.0
TLS2_k127_3825491_55 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000002684 188.0
TLS2_k127_3825491_56 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000001405 202.0
TLS2_k127_3825491_57 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000005035 202.0
TLS2_k127_3825491_58 Glutaredoxin - - - 0.000000000000000000000000000000000000000000000001752 176.0
TLS2_k127_3825491_59 zinc ion binding K06204 - - 0.00000000000000000000000000000000000000000000002277 172.0
TLS2_k127_3825491_6 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP - - - 5.193e-246 761.0
TLS2_k127_3825491_60 K+-transporting ATPase, c chain K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000004403 176.0
TLS2_k127_3825491_61 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000006109 168.0
TLS2_k127_3825491_62 Hemerythrin HHE cation binding domain K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000002257 166.0
TLS2_k127_3825491_64 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000000000000001617 175.0
TLS2_k127_3825491_65 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000000000000000000000000000000000002344 179.0
TLS2_k127_3825491_66 CAAX protease self-immunity K07052,K09696 - - 0.000000000000000000000000000000000000000005543 164.0
TLS2_k127_3825491_67 - - - - 0.0000000000000000000000000000000000001329 149.0
TLS2_k127_3825491_68 KR domain K07124 - - 0.0000000000000000000000000000000000002474 162.0
TLS2_k127_3825491_69 HEAT repeat - - - 0.00000000000000000000000000000000001037 147.0
TLS2_k127_3825491_7 HsdM N-terminal domain K03427 - 2.1.1.72 6.281e-228 713.0
TLS2_k127_3825491_70 oxidoreductase activity K02293 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009507,GO:0009526,GO:0009534,GO:0009536,GO:0009579,GO:0009941,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016166,GO:0016491,GO:0016627,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0042440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0055114,GO:0071704,GO:1901576 1.3.5.5 0.00000000000000000000000000001082 135.0
TLS2_k127_3825491_71 COG3473 Maleate cis-trans isomerase - - - 0.0000000000000000000000000008333 119.0
TLS2_k127_3825491_75 Transposase IS66 family K07484 - - 0.0000000000000000000001473 108.0
TLS2_k127_3825491_77 Trypsin-like serine protease - - - 0.000000000000000000001396 108.0
TLS2_k127_3825491_78 Transposase IS200 like - - - 0.00000000000007235 84.0
TLS2_k127_3825491_8 serine threonine protein kinase K08884,K12132 - 2.7.11.1 4.616e-221 694.0
TLS2_k127_3825491_80 PBS lyase HEAT-like repeat - - - 0.0000000000007887 82.0
TLS2_k127_3825491_81 - - - - 0.000000001856 61.0
TLS2_k127_3825491_82 Bacterial toxin 34 - - - 0.0000000169 66.0
TLS2_k127_3825491_83 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000008932 59.0
TLS2_k127_3825491_84 - - - - 0.0000006218 62.0
TLS2_k127_3825491_85 S23 ribosomal protein - - - 0.00009677 52.0
TLS2_k127_3825491_86 Helix-turn-helix - - - 0.0002478 46.0
TLS2_k127_3825491_87 - - - - 0.0002925 52.0
TLS2_k127_3825491_9 Aminotransferase - - - 5.511e-219 687.0
TLS2_k127_3845229_1 Restriction endonuclease fold toxin 5 - - - 0.00000000000000000000000000004857 134.0
TLS2_k127_3845229_2 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH - - - 0.00000000000000000000055 111.0
TLS2_k127_3891593_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1641.0
TLS2_k127_3891593_1 Pfam:DUF490 K09800 - - 0.0 1416.0
TLS2_k127_3891593_10 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 589.0
TLS2_k127_3891593_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 570.0
TLS2_k127_3891593_12 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 573.0
TLS2_k127_3891593_13 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K12583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 562.0
TLS2_k127_3891593_14 Belongs to the GcvT family K00302,K10815 - 1.4.99.5,1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 551.0
TLS2_k127_3891593_15 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 537.0
TLS2_k127_3891593_16 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 531.0
TLS2_k127_3891593_17 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 515.0
TLS2_k127_3891593_18 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 517.0
TLS2_k127_3891593_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 525.0
TLS2_k127_3891593_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1031.0
TLS2_k127_3891593_20 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 511.0
TLS2_k127_3891593_21 Lipopolysaccharide kinase (Kdo/WaaP) family K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 515.0
TLS2_k127_3891593_22 COG2084 3-hydroxyisobutyrate dehydrogenase and related K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 469.0
TLS2_k127_3891593_23 RelA SpoT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 433.0
TLS2_k127_3891593_25 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 416.0
TLS2_k127_3891593_26 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 400.0
TLS2_k127_3891593_27 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 400.0
TLS2_k127_3891593_28 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 402.0
TLS2_k127_3891593_29 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 392.0
TLS2_k127_3891593_3 Surface antigen K07277 - - 1.267e-305 1028.0
TLS2_k127_3891593_30 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 396.0
TLS2_k127_3891593_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 379.0
TLS2_k127_3891593_34 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 375.0
TLS2_k127_3891593_35 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 372.0
TLS2_k127_3891593_36 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 372.0
TLS2_k127_3891593_37 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 365.0
TLS2_k127_3891593_38 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 364.0
TLS2_k127_3891593_39 FHA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 356.0
TLS2_k127_3891593_4 Cytochrome b subunit of the bc complex K00412 - - 1.95e-293 908.0
TLS2_k127_3891593_41 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 338.0
TLS2_k127_3891593_42 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 323.0
TLS2_k127_3891593_43 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K11275 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 325.0
TLS2_k127_3891593_45 metallopeptidase activity K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 304.0
TLS2_k127_3891593_46 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 286.0
TLS2_k127_3891593_47 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001644 287.0
TLS2_k127_3891593_48 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001385 283.0
TLS2_k127_3891593_49 Protein of unknown function (DUF507) K09804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001175 271.0
TLS2_k127_3891593_5 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 2.876e-255 792.0
TLS2_k127_3891593_50 - K00712 - 2.4.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000004402 260.0
TLS2_k127_3891593_51 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005582 258.0
TLS2_k127_3891593_52 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007496 245.0
TLS2_k127_3891593_53 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000002033 248.0
TLS2_k127_3891593_54 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002344 225.0
TLS2_k127_3891593_55 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000326 226.0
TLS2_k127_3891593_56 S-acyltransferase activity K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000001189 212.0
TLS2_k127_3891593_57 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000003129 195.0
TLS2_k127_3891593_58 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000001194 192.0
TLS2_k127_3891593_6 Sarcosine oxidase K00303 - 1.5.3.1 7.707e-202 636.0
TLS2_k127_3891593_60 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000001387 178.0
TLS2_k127_3891593_63 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000005663 153.0
TLS2_k127_3891593_64 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000006325 151.0
TLS2_k127_3891593_65 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000000002319 149.0
TLS2_k127_3891593_68 Ribbon-helix-helix domain - - - 0.00000000000000000000002968 101.0
TLS2_k127_3891593_7 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.766e-197 625.0
TLS2_k127_3891593_70 histone H2A K63-linked ubiquitination K01768 - 4.6.1.1 0.000000000000000002347 91.0
TLS2_k127_3891593_71 PFAM Phosphate-selective porin O and P - - - 0.00000000000003152 86.0
TLS2_k127_3891593_8 Type II IV secretion system protein K02283,K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 625.0
TLS2_k127_3891593_9 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 619.0
TLS2_k127_3903848_0 synthase K12436 - - 0.0 1634.0
TLS2_k127_3903848_1 PKS_DH K12436,K16396,K16397 - - 0.0 1424.0
TLS2_k127_3903848_10 Saccharopine dehydrogenase NADP binding domain K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 319.0
TLS2_k127_3903848_11 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 K18586 - - 0.00000000000000000000000000000000000000000000000000001359 198.0
TLS2_k127_3903848_12 Cupin-like domain - - - 0.000000000000000000000000000000000002395 155.0
TLS2_k127_3903848_13 - - - - 0.00000000000000000000004795 109.0
TLS2_k127_3903848_2 PFAM Phosphopantetheine attachment site - - - 0.0 1249.0
TLS2_k127_3903848_3 synthase - - - 0.0 1058.0
TLS2_k127_3903848_4 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.0 1055.0
TLS2_k127_3903848_5 PFAM short-chain dehydrogenase reductase SDR - - - 5.053e-316 1021.0
TLS2_k127_3903848_6 Ami_2 - - - 1.306e-219 700.0
TLS2_k127_3903848_7 polyketide synthase K21792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 631.0
TLS2_k127_3903848_8 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 483.0
TLS2_k127_3903848_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 484.0
TLS2_k127_4009770_0 helicase - - - 0.0 1839.0
TLS2_k127_4009770_1 Pfam:Methyltransf_26 - - - 0.0 1697.0
TLS2_k127_4009770_10 Protein of unknown function, DUF255 K06888 - - 2.376e-321 998.0
TLS2_k127_4009770_100 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000002945 191.0
TLS2_k127_4009770_101 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000006427 202.0
TLS2_k127_4009770_102 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.00000000000000000000000000000000000000000000000001337 181.0
TLS2_k127_4009770_103 Penicillin binding protein transpeptidase domain K17838 - 3.5.2.6 0.00000000000000000000000000000000000000000000000005709 191.0
TLS2_k127_4009770_104 - - - - 0.0000000000000000000000000000000000000000000000001053 185.0
TLS2_k127_4009770_105 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000001171 184.0
TLS2_k127_4009770_106 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.000000000000000000000000000000000000000000007414 166.0
TLS2_k127_4009770_108 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000006912 165.0
TLS2_k127_4009770_109 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.0000000000000000000000000000000000003557 162.0
TLS2_k127_4009770_11 aminopeptidase N - - - 4.54e-317 1004.0
TLS2_k127_4009770_111 Phosphocarrier protein HPR K11189 - - 0.0000000000000000000000000000000003743 136.0
TLS2_k127_4009770_112 response to heat K07090 - - 0.00000000000000000000000000000004663 136.0
TLS2_k127_4009770_114 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000007126 140.0
TLS2_k127_4009770_115 Smr domain - - - 0.000000000000000000000000000001015 128.0
TLS2_k127_4009770_116 - - - - 0.000000000000000000000000000006034 132.0
TLS2_k127_4009770_117 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000002086 136.0
TLS2_k127_4009770_118 Chloramphenicol phosphotransferase-like protein K18554 - - 0.0000000000000000000000000001444 126.0
TLS2_k127_4009770_119 zinc-finger binding domain of transposase IS66 - - - 0.000000000000000000000000004084 119.0
TLS2_k127_4009770_12 PglZ domain - - - 1.883e-316 997.0
TLS2_k127_4009770_120 protein kinase activity - - - 0.00000000000000000000000001828 121.0
TLS2_k127_4009770_121 Iron-sulphur cluster assembly - - - 0.00000000000000000000000002736 109.0
TLS2_k127_4009770_122 Major Facilitator Superfamily - - - 0.00000000000000000000000007456 121.0
TLS2_k127_4009770_123 - - - - 0.00000000000000000000000008751 117.0
TLS2_k127_4009770_124 - - - - 0.0000000000000000000000008489 109.0
TLS2_k127_4009770_125 Protein of unknown function (DUF3421) - - - 0.000000000000000000000001328 111.0
TLS2_k127_4009770_127 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000003156 105.0
TLS2_k127_4009770_129 biopolymer transport protein K03559 GO:0003674,GO:0005215 - 0.00000000000000000000008585 113.0
TLS2_k127_4009770_13 Protein of unknown function (DUF1156) K07445 - - 3.503e-309 975.0
TLS2_k127_4009770_130 Transglutaminase elicitor - - - 0.000000000000000000007674 108.0
TLS2_k127_4009770_131 - - - - 0.000000000000000002908 98.0
TLS2_k127_4009770_132 Excisionase - - - 0.0000000000000002246 82.0
TLS2_k127_4009770_133 High confidence in function and specificity K07484 - - 0.0000000000000005664 85.0
TLS2_k127_4009770_134 YXWGXW repeat (2 copies) - - - 0.0000000000000009501 83.0
TLS2_k127_4009770_135 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00000000000000149 89.0
TLS2_k127_4009770_136 Pfam:DUF91 - - - 0.00000000000575 76.0
TLS2_k127_4009770_138 Regulator of chromosome condensation - - - 0.0000000004588 66.0
TLS2_k127_4009770_139 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000002915 69.0
TLS2_k127_4009770_14 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 8.062e-306 949.0
TLS2_k127_4009770_140 regulation of methylation-dependent chromatin silencing K07454 - - 0.0000008233 60.0
TLS2_k127_4009770_142 PFAM Integrase catalytic K07497 - - 0.00002454 50.0
TLS2_k127_4009770_143 - - - - 0.00007869 51.0
TLS2_k127_4009770_144 - - - - 0.0006503 50.0
TLS2_k127_4009770_15 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.827e-295 913.0
TLS2_k127_4009770_16 metal-dependent phosphohydrolase HD - - - 5.247e-294 907.0
TLS2_k127_4009770_17 RNA secondary structure unwinding K03724 - - 9.874e-257 836.0
TLS2_k127_4009770_18 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.123e-250 780.0
TLS2_k127_4009770_19 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 8.324e-241 753.0
TLS2_k127_4009770_2 RNA-binding protein homologous to eukaryotic snRNP - - - 0.0 1571.0
TLS2_k127_4009770_20 PFAM Archaeal ATPase - - - 4.389e-224 705.0
TLS2_k127_4009770_21 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.132e-218 683.0
TLS2_k127_4009770_22 Serine Threonine protein kinase - - - 2.685e-213 682.0
TLS2_k127_4009770_23 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 3.651e-203 638.0
TLS2_k127_4009770_24 Belongs to the aspartokinase family K00928 - 2.7.2.4 5.771e-197 627.0
TLS2_k127_4009770_25 VWA domain containing CoxE-like protein K09989 - - 4.293e-196 617.0
TLS2_k127_4009770_26 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 607.0
TLS2_k127_4009770_27 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 565.0
TLS2_k127_4009770_28 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 567.0
TLS2_k127_4009770_29 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 564.0
TLS2_k127_4009770_3 Amidohydrolase family - - - 0.0 1567.0
TLS2_k127_4009770_30 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 555.0
TLS2_k127_4009770_31 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 547.0
TLS2_k127_4009770_32 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 542.0
TLS2_k127_4009770_33 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 541.0
TLS2_k127_4009770_34 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 535.0
TLS2_k127_4009770_35 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 552.0
TLS2_k127_4009770_36 P-loop Domain of unknown function (DUF2791) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 539.0
TLS2_k127_4009770_37 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 532.0
TLS2_k127_4009770_38 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 505.0
TLS2_k127_4009770_39 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 508.0
TLS2_k127_4009770_4 Protein of unknown function (DUF1156) K07445 - - 0.0 1472.0
TLS2_k127_4009770_40 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 501.0
TLS2_k127_4009770_42 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 462.0
TLS2_k127_4009770_44 Serine Threonine protein kinase K01286,K08884,K12132 - 2.7.11.1,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 467.0
TLS2_k127_4009770_45 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 430.0
TLS2_k127_4009770_46 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 429.0
TLS2_k127_4009770_47 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 423.0
TLS2_k127_4009770_48 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 428.0
TLS2_k127_4009770_49 12 heme-binding sites - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 440.0
TLS2_k127_4009770_5 ATPase (AAA superfamily - - - 0.0 1448.0
TLS2_k127_4009770_50 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 422.0
TLS2_k127_4009770_51 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 407.0
TLS2_k127_4009770_52 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 396.0
TLS2_k127_4009770_53 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 397.0
TLS2_k127_4009770_54 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 397.0
TLS2_k127_4009770_55 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 391.0
TLS2_k127_4009770_56 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 388.0
TLS2_k127_4009770_57 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 366.0
TLS2_k127_4009770_58 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 367.0
TLS2_k127_4009770_59 defense response to virus K07061 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 357.0
TLS2_k127_4009770_6 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1272.0
TLS2_k127_4009770_60 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 370.0
TLS2_k127_4009770_61 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 329.0
TLS2_k127_4009770_62 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 333.0
TLS2_k127_4009770_63 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 336.0
TLS2_k127_4009770_64 RAMP superfamily K09000 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 337.0
TLS2_k127_4009770_66 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 324.0
TLS2_k127_4009770_67 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 314.0
TLS2_k127_4009770_68 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 296.0
TLS2_k127_4009770_69 RAMP superfamily K19076,K19142 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 297.0
TLS2_k127_4009770_7 crispr-associated protein K07016 - - 0.0 1058.0
TLS2_k127_4009770_70 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 300.0
TLS2_k127_4009770_71 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 283.0
TLS2_k127_4009770_72 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002882 291.0
TLS2_k127_4009770_73 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005411 310.0
TLS2_k127_4009770_74 Putative transposase, YhgA-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005618 287.0
TLS2_k127_4009770_75 PilZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007893 305.0
TLS2_k127_4009770_76 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005312 271.0
TLS2_k127_4009770_77 RAMP superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 278.0
TLS2_k127_4009770_78 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000382 274.0
TLS2_k127_4009770_79 Domain of unknown function (DUF1788) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003245 278.0
TLS2_k127_4009770_8 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1009.0
TLS2_k127_4009770_80 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001195 272.0
TLS2_k127_4009770_82 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002463 286.0
TLS2_k127_4009770_83 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005799 255.0
TLS2_k127_4009770_84 Protein of unknown function, DUF481 K07283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001513 247.0
TLS2_k127_4009770_85 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000001874 267.0
TLS2_k127_4009770_86 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001994 252.0
TLS2_k127_4009770_87 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002505 242.0
TLS2_k127_4009770_88 UreD urease accessory protein K03190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000844 240.0
TLS2_k127_4009770_89 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001027 237.0
TLS2_k127_4009770_9 glutamate--cysteine ligase - - - 0.0 1005.0
TLS2_k127_4009770_90 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00000000000000000000000000000000000000000000000000000000000000673 225.0
TLS2_k127_4009770_93 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000001019 239.0
TLS2_k127_4009770_94 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000000000000000000000000000122 221.0
TLS2_k127_4009770_95 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000000001446 218.0
TLS2_k127_4009770_96 - - - - 0.000000000000000000000000000000000000000000000000000000000461 209.0
TLS2_k127_4009770_97 nitric oxide dioxygenase activity K05916 - 1.14.12.17 0.000000000000000000000000000000000000000000000000000000003856 212.0
TLS2_k127_4009770_98 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000000000000001065 221.0
TLS2_k127_4009770_99 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000003864 197.0
TLS2_k127_4036818_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 5.101e-242 780.0
TLS2_k127_4036818_1 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 439.0
TLS2_k127_4036818_10 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000001266 203.0
TLS2_k127_4036818_11 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.000000000000000000000000000000009552 141.0
TLS2_k127_4036818_12 SnoaL-like domain - - - 0.000000000000000000000002599 119.0
TLS2_k127_4036818_13 bacterial-type flagellum organization - - - 0.00000005012 58.0
TLS2_k127_4036818_14 40-residue YVTN family beta-propeller repeat - - - 0.000002685 60.0
TLS2_k127_4036818_2 Predicted AAA-ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 434.0
TLS2_k127_4036818_3 PFAM iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 432.0
TLS2_k127_4036818_4 Catechol dioxygenase N terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 329.0
TLS2_k127_4036818_5 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 321.0
TLS2_k127_4036818_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 284.0
TLS2_k127_4036818_7 Coenzyme A transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001096 274.0
TLS2_k127_4036818_8 HEPN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008314 229.0
TLS2_k127_4036818_9 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000008454 246.0
TLS2_k127_4097587_0 Two component regulator propeller - - - 0.0 1180.0
TLS2_k127_4097587_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.028e-301 941.0
TLS2_k127_4097587_10 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 1.403e-196 629.0
TLS2_k127_4097587_11 glycosyl transferase family K20436 - 2.5.1.135 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 582.0
TLS2_k127_4097587_12 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K20435 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 587.0
TLS2_k127_4097587_13 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K13747 - 4.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 541.0
TLS2_k127_4097587_14 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 538.0
TLS2_k127_4097587_15 sugar phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 467.0
TLS2_k127_4097587_16 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 445.0
TLS2_k127_4097587_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 386.0
TLS2_k127_4097587_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 386.0
TLS2_k127_4097587_19 Glucose-methanol-choline (GMC) oxidoreductase NAD binding site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 386.0
TLS2_k127_4097587_2 Bacterial protein of unknown function (DUF839) K07093 - - 1.943e-278 878.0
TLS2_k127_4097587_20 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 368.0
TLS2_k127_4097587_21 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 341.0
TLS2_k127_4097587_22 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 345.0
TLS2_k127_4097587_23 His Kinase A (phosphoacceptor) domain K13587 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 331.0
TLS2_k127_4097587_24 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 337.0
TLS2_k127_4097587_25 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 326.0
TLS2_k127_4097587_26 alcohol dehydrogenase K20434 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 295.0
TLS2_k127_4097587_28 RmlD substrate binding domain K20432 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002027 289.0
TLS2_k127_4097587_29 ADP-glyceromanno-heptose 6-epimerase activity K01955,K16703 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002846 288.0
TLS2_k127_4097587_3 PAS fold - - - 1.767e-242 757.0
TLS2_k127_4097587_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001498 281.0
TLS2_k127_4097587_31 N-acetylglucosamine kinase activity K18676 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000691 280.0
TLS2_k127_4097587_32 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000001758 261.0
TLS2_k127_4097587_33 GGDEF domain K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000002928 264.0
TLS2_k127_4097587_34 chlorophyll binding K02067,K03286,K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002822 261.0
TLS2_k127_4097587_35 VanW like protein K18346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003306 249.0
TLS2_k127_4097587_37 - - - - 0.000000000000000000000000000000000000000000000000000013 193.0
TLS2_k127_4097587_38 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000001194 195.0
TLS2_k127_4097587_39 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000006221 201.0
TLS2_k127_4097587_4 Tetratricopeptide repeat - - - 3.213e-236 762.0
TLS2_k127_4097587_41 YhhN family - - - 0.000000000000000000000000000000000000000000006027 174.0
TLS2_k127_4097587_42 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000002172 178.0
TLS2_k127_4097587_43 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000002081 166.0
TLS2_k127_4097587_47 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000329 94.0
TLS2_k127_4097587_48 translation initiation factor activity K06996 - - 0.00000006042 66.0
TLS2_k127_4097587_49 PDZ domain (Also known as DHR K04771 - 3.4.21.107 0.00000009293 63.0
TLS2_k127_4097587_5 PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 1.662e-234 749.0
TLS2_k127_4097587_6 PFAM Saccharopine dehydrogenase K00290 - 1.5.1.7 1.444e-227 707.0
TLS2_k127_4097587_7 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 7.974e-223 700.0
TLS2_k127_4097587_8 Cytochrome c - - - 2.266e-218 692.0
TLS2_k127_4097587_9 Glycosyl Transferase - - - 3.761e-211 680.0
TLS2_k127_4121538_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 4.937e-311 967.0
TLS2_k127_4121538_1 HRDC domain protein K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 422.0
TLS2_k127_4128624_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.171e-287 903.0
TLS2_k127_4128624_1 polysaccharide biosynthetic process K06409 - - 2.12e-210 668.0
TLS2_k127_4128624_10 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 409.0
TLS2_k127_4128624_11 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 396.0
TLS2_k127_4128624_12 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 372.0
TLS2_k127_4128624_13 belongs to the thioredoxin family K00384,K02453,K11912,K20543 - 1.8.1.9,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 371.0
TLS2_k127_4128624_14 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 353.0
TLS2_k127_4128624_15 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 328.0
TLS2_k127_4128624_16 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 319.0
TLS2_k127_4128624_17 purine-nucleoside phosphorylase K03784 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 310.0
TLS2_k127_4128624_19 arabinose efflux permease K18567 - - 0.0000000000000000000000000000000000000000000000000000000000000002231 235.0
TLS2_k127_4128624_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.912e-198 625.0
TLS2_k127_4128624_20 long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000003349 246.0
TLS2_k127_4128624_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000003443 230.0
TLS2_k127_4128624_22 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000005437 232.0
TLS2_k127_4128624_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000001049 226.0
TLS2_k127_4128624_24 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000004819 216.0
TLS2_k127_4128624_25 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000007104 207.0
TLS2_k127_4128624_26 - - - - 0.0000000000000000000000000000000000000001175 157.0
TLS2_k127_4128624_3 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 607.0
TLS2_k127_4128624_30 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000001696 105.0
TLS2_k127_4128624_31 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000003371 102.0
TLS2_k127_4128624_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 565.0
TLS2_k127_4128624_5 S-acyltransferase activity K02487,K06596,K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 514.0
TLS2_k127_4128624_6 PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 500.0
TLS2_k127_4128624_7 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 507.0
TLS2_k127_4128624_8 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 505.0
TLS2_k127_4128624_9 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00480 - 1.14.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 455.0
TLS2_k127_41856_0 SMART Elongator protein 3 MiaB NifB - - - 0.0 1382.0
TLS2_k127_41856_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 6.294e-308 978.0
TLS2_k127_41856_10 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001247 284.0
TLS2_k127_41856_11 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000002036 244.0
TLS2_k127_41856_12 bacterial-type flagellum organization - - - 0.00000000000000000000000000000000000000000000000000000000000001148 239.0
TLS2_k127_41856_13 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000001699 211.0
TLS2_k127_41856_14 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000001137 209.0
TLS2_k127_41856_2 SMART Integrin alpha beta-propellor repeat protein - - - 4.607e-198 643.0
TLS2_k127_41856_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 508.0
TLS2_k127_41856_4 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 497.0
TLS2_k127_41856_5 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K01784,K02473,K08678 - 4.1.1.35,4.2.1.46,5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 435.0
TLS2_k127_41856_6 Male sterility protein K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 417.0
TLS2_k127_41856_7 A-macroglobulin receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 421.0
TLS2_k127_41856_8 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 308.0
TLS2_k127_41856_9 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 291.0
TLS2_k127_4232939_0 domain protein K21147 - 2.7.7.80,2.8.1.11 1.115e-211 662.0
TLS2_k127_4232939_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 4.733e-210 670.0
TLS2_k127_4232939_10 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 515.0
TLS2_k127_4232939_11 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 459.0
TLS2_k127_4232939_12 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 424.0
TLS2_k127_4232939_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 373.0
TLS2_k127_4232939_14 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 399.0
TLS2_k127_4232939_15 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 292.0
TLS2_k127_4232939_16 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 287.0
TLS2_k127_4232939_17 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002484 273.0
TLS2_k127_4232939_18 ribosomal L5P family C-terminus K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001038 273.0
TLS2_k127_4232939_19 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000009901 238.0
TLS2_k127_4232939_2 Endoribonuclease that initiates mRNA decay K18682 - - 2.964e-208 659.0
TLS2_k127_4232939_20 MerR, DNA binding K19591 - - 0.00000000000000000000000000000000000000000000000000000000000000000005819 237.0
TLS2_k127_4232939_21 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002912 222.0
TLS2_k127_4232939_22 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000002324 217.0
TLS2_k127_4232939_23 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000007868 217.0
TLS2_k127_4232939_24 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000002146 216.0
TLS2_k127_4232939_25 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000003786 206.0
TLS2_k127_4232939_26 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001263 208.0
TLS2_k127_4232939_27 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000001433 192.0
TLS2_k127_4232939_28 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000001192 189.0
TLS2_k127_4232939_29 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000001752 186.0
TLS2_k127_4232939_3 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 5.811e-204 647.0
TLS2_k127_4232939_30 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000003405 183.0
TLS2_k127_4232939_31 Thioesterase-like superfamily K01075 - 3.1.2.23 0.0000000000000000000000000000000000000000000000004884 184.0
TLS2_k127_4232939_32 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000002341 183.0
TLS2_k127_4232939_33 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000003212 159.0
TLS2_k127_4232939_34 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000003547 137.0
TLS2_k127_4232939_35 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000456 138.0
TLS2_k127_4232939_36 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000545 139.0
TLS2_k127_4232939_37 Domain of unknown function (DUF4215) - - - 0.000000000000000000000000317 124.0
TLS2_k127_4232939_38 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000009157 122.0
TLS2_k127_4232939_39 Bacterial membrane protein YfhO - - - 0.00000000000000000000008676 115.0
TLS2_k127_4232939_4 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 2.849e-197 631.0
TLS2_k127_4232939_40 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000009888 96.0
TLS2_k127_4232939_41 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000004228 99.0
TLS2_k127_4232939_42 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000002036 94.0
TLS2_k127_4232939_43 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000004266 70.0
TLS2_k127_4232939_44 Ribosomal protein L30 K02907 - - 0.00000000001424 68.0
TLS2_k127_4232939_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 582.0
TLS2_k127_4232939_6 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 568.0
TLS2_k127_4232939_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 581.0
TLS2_k127_4232939_8 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 576.0
TLS2_k127_4232939_9 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 575.0
TLS2_k127_458177_0 repeat protein - - - 0.0 5210.0
TLS2_k127_458177_1 PKS_DH - - - 0.0 2695.0
TLS2_k127_458177_10 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 4.5e-284 889.0
TLS2_k127_458177_100 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000001269 222.0
TLS2_k127_458177_101 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002837 220.0
TLS2_k127_458177_102 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000004357 222.0
TLS2_k127_458177_103 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000000000003554 196.0
TLS2_k127_458177_104 - - - - 0.0000000000000000000000000000000000000000000000000000004099 212.0
TLS2_k127_458177_105 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000007431 208.0
TLS2_k127_458177_106 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000001434 191.0
TLS2_k127_458177_107 - - - - 0.00000000000000000000000000000000000000000000002506 187.0
TLS2_k127_458177_108 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000001288 183.0
TLS2_k127_458177_109 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000000000000000000000008483 166.0
TLS2_k127_458177_11 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 5.743e-284 878.0
TLS2_k127_458177_110 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000003325 175.0
TLS2_k127_458177_111 Putative molybdenum carrier - - - 0.00000000000000000000000000000000000000000009647 167.0
TLS2_k127_458177_112 antibiotic catabolic process K13277 - - 0.0000000000000000000000000000000000000000002756 179.0
TLS2_k127_458177_113 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000000000000000000000003371 155.0
TLS2_k127_458177_114 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000005207 156.0
TLS2_k127_458177_115 - - - - 0.000000000000000000000000000000000000000863 162.0
TLS2_k127_458177_117 - - - - 0.0000000000000000000000000000000000000189 149.0
TLS2_k127_458177_119 - - - - 0.0000000000000000000000000000000000002118 156.0
TLS2_k127_458177_12 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 1.759e-278 863.0
TLS2_k127_458177_121 GtrA-like protein K00995 - 2.7.8.5 0.000000000000000000000000000000000000394 152.0
TLS2_k127_458177_122 - - - - 0.000000000000000000000000000000000000673 148.0
TLS2_k127_458177_123 Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000001226 144.0
TLS2_k127_458177_124 secreted protein - - - 0.000000000000000000000000000000000002597 147.0
TLS2_k127_458177_125 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000000000006688 155.0
TLS2_k127_458177_126 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000002881 130.0
TLS2_k127_458177_127 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000001368 129.0
TLS2_k127_458177_128 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000001718 142.0
TLS2_k127_458177_129 Outer membrane efflux protein - - - 0.00000000000000000000000000000002812 145.0
TLS2_k127_458177_13 glutamine synthetase K01915 - 6.3.1.2 3.022e-278 862.0
TLS2_k127_458177_130 energy transducer activity K03832 - - 0.0000000000000000000000000000002289 133.0
TLS2_k127_458177_131 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000004637 131.0
TLS2_k127_458177_132 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000002155 125.0
TLS2_k127_458177_133 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000003342 128.0
TLS2_k127_458177_135 - - - - 0.0000000000000000000000551 102.0
TLS2_k127_458177_136 MlaC protein K07323 - - 0.000000000000000000001662 106.0
TLS2_k127_458177_137 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000001444 88.0
TLS2_k127_458177_138 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000003647 83.0
TLS2_k127_458177_139 Transglutaminase elicitor - - - 0.00000000000003245 86.0
TLS2_k127_458177_14 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 2.338e-261 811.0
TLS2_k127_458177_141 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000692 67.0
TLS2_k127_458177_142 pyrroloquinoline quinone binding - - - 0.000000008646 68.0
TLS2_k127_458177_143 - - - - 0.0000009996 59.0
TLS2_k127_458177_144 S23 ribosomal protein - - - 0.00001654 53.0
TLS2_k127_458177_145 - - - - 0.0003338 46.0
TLS2_k127_458177_15 FAD binding domain - - - 3.805e-261 813.0
TLS2_k127_458177_16 Predicted membrane protein (DUF2254) - - - 4.318e-253 792.0
TLS2_k127_458177_17 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 1.073e-252 791.0
TLS2_k127_458177_18 Tetratricopeptide repeat - - - 2.645e-240 752.0
TLS2_k127_458177_19 Cytochrome P450 - - - 2.513e-238 761.0
TLS2_k127_458177_2 non-ribosomal peptide synthetase - - - 0.0 1768.0
TLS2_k127_458177_20 Flavin containing amine oxidoreductase - - - 4.421e-238 746.0
TLS2_k127_458177_21 His Kinase A (phosphoacceptor) domain - - - 1.188e-230 723.0
TLS2_k127_458177_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 2.924e-229 713.0
TLS2_k127_458177_23 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.403e-218 693.0
TLS2_k127_458177_24 AAA ATPase domain - - - 7.073e-216 711.0
TLS2_k127_458177_25 Cytochrome c554 and c-prime - - - 3e-206 659.0
TLS2_k127_458177_26 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 1.334e-202 647.0
TLS2_k127_458177_27 N-6 DNA Methylase - - - 1.943e-197 630.0
TLS2_k127_458177_28 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 8.347e-197 626.0
TLS2_k127_458177_29 Mitochondrial biogenesis AIM24 - - - 1.152e-195 624.0
TLS2_k127_458177_3 Tetratricopeptide repeat - - - 0.0 1663.0
TLS2_k127_458177_30 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 617.0
TLS2_k127_458177_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 608.0
TLS2_k127_458177_32 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 603.0
TLS2_k127_458177_33 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 638.0
TLS2_k127_458177_34 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 582.0
TLS2_k127_458177_35 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 571.0
TLS2_k127_458177_36 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 565.0
TLS2_k127_458177_37 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 544.0
TLS2_k127_458177_38 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 527.0
TLS2_k127_458177_39 Mn2 and Fe2 transporters of the NRAMP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 525.0
TLS2_k127_458177_4 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.0 1570.0
TLS2_k127_458177_40 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 518.0
TLS2_k127_458177_41 adventurous gliding protein T - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 510.0
TLS2_k127_458177_42 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 504.0
TLS2_k127_458177_43 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 514.0
TLS2_k127_458177_44 PFAM Cobalamin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 491.0
TLS2_k127_458177_45 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 481.0
TLS2_k127_458177_46 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 459.0
TLS2_k127_458177_47 AI-2E family transporter K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 449.0
TLS2_k127_458177_48 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 450.0
TLS2_k127_458177_49 UPF0365 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 452.0
TLS2_k127_458177_5 WD40-like Beta Propeller Repeat - - - 0.0 1328.0
TLS2_k127_458177_50 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 442.0
TLS2_k127_458177_51 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 427.0
TLS2_k127_458177_52 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 444.0
TLS2_k127_458177_53 Histidine kinase K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 437.0
TLS2_k127_458177_54 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 430.0
TLS2_k127_458177_55 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 423.0
TLS2_k127_458177_56 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 434.0
TLS2_k127_458177_57 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 432.0
TLS2_k127_458177_58 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 434.0
TLS2_k127_458177_59 AAA domain K10742 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 442.0
TLS2_k127_458177_6 FHA domain - - - 2.959e-297 933.0
TLS2_k127_458177_60 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 415.0
TLS2_k127_458177_61 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 391.0
TLS2_k127_458177_62 Iron-containing redox enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 372.0
TLS2_k127_458177_63 Domain of unknown function (DUF4956) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 372.0
TLS2_k127_458177_64 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 370.0
TLS2_k127_458177_65 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 361.0
TLS2_k127_458177_66 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 360.0
TLS2_k127_458177_67 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 353.0
TLS2_k127_458177_68 Zinc-dependent metalloprotease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 377.0
TLS2_k127_458177_69 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 351.0
TLS2_k127_458177_7 Voltage gated chloride channel K03281 - - 6.683e-292 908.0
TLS2_k127_458177_70 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 346.0
TLS2_k127_458177_71 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 344.0
TLS2_k127_458177_72 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 353.0
TLS2_k127_458177_73 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 344.0
TLS2_k127_458177_74 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 332.0
TLS2_k127_458177_75 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 323.0
TLS2_k127_458177_76 Transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 325.0
TLS2_k127_458177_77 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 322.0
TLS2_k127_458177_78 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 326.0
TLS2_k127_458177_79 Transcriptional regulator, CarD family K07736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 309.0
TLS2_k127_458177_8 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.062e-288 905.0
TLS2_k127_458177_80 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 316.0
TLS2_k127_458177_81 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 297.0
TLS2_k127_458177_82 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 312.0
TLS2_k127_458177_83 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 305.0
TLS2_k127_458177_84 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002123 285.0
TLS2_k127_458177_85 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001811 278.0
TLS2_k127_458177_86 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004613 274.0
TLS2_k127_458177_87 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 263.0
TLS2_k127_458177_88 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007389 261.0
TLS2_k127_458177_89 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001211 272.0
TLS2_k127_458177_9 Belongs to the IlvD Edd family K01690,K22186,K22396 - 4.2.1.12,4.2.1.82 2.621e-285 887.0
TLS2_k127_458177_90 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000184 257.0
TLS2_k127_458177_91 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000001449 245.0
TLS2_k127_458177_92 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001511 261.0
TLS2_k127_458177_93 alpha/beta hydrolase fold K08680 - 4.2.99.20 0.000000000000000000000000000000000000000000000000000000000000000000001465 247.0
TLS2_k127_458177_95 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001773 235.0
TLS2_k127_458177_96 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000000002858 232.0
TLS2_k127_458177_97 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000000000000000008088 252.0
TLS2_k127_458177_99 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000003071 226.0
TLS2_k127_4596575_0 lysine biosynthetic process via aminoadipic acid - - - 1.218e-212 696.0
TLS2_k127_4596575_1 UDP binding domain K02474,K13015 - 1.1.1.136 1.162e-206 649.0
TLS2_k127_4596575_10 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 374.0
TLS2_k127_4596575_11 Pfam:HipA_N K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 381.0
TLS2_k127_4596575_12 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 362.0
TLS2_k127_4596575_13 Enoyl-(Acyl carrier protein) reductase K00216,K13774 - 1.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 348.0
TLS2_k127_4596575_14 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 343.0
TLS2_k127_4596575_15 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 321.0
TLS2_k127_4596575_16 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 308.0
TLS2_k127_4596575_17 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 295.0
TLS2_k127_4596575_19 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002048 266.0
TLS2_k127_4596575_2 Polysaccharide biosynthesis protein K01784,K02473 - 5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 513.0
TLS2_k127_4596575_20 3-beta hydroxysteroid dehydrogenase/isomerase family K22320 - 1.1.1.412 0.000000000000000000000000000000000000000000000000000000000000000000005072 246.0
TLS2_k127_4596575_21 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000000000000000000000000114 222.0
TLS2_k127_4596575_22 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000006199 214.0
TLS2_k127_4596575_23 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000005989 211.0
TLS2_k127_4596575_24 - - - - 0.00000000000000000000000000000000000000000003064 161.0
TLS2_k127_4596575_25 - - - - 0.00000000000000000000000000000000000000000005448 173.0
TLS2_k127_4596575_26 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000001897 162.0
TLS2_k127_4596575_27 B12 binding domain - - - 0.00000000000000000000000000000000001311 156.0
TLS2_k127_4596575_28 methyltransferase - - - 0.00000000000000000000000000006744 124.0
TLS2_k127_4596575_29 Transposase IS66 family K07484 - - 0.0000000000000000000000000003488 121.0
TLS2_k127_4596575_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 504.0
TLS2_k127_4596575_30 - - - - 0.00000000000000000004696 90.0
TLS2_k127_4596575_32 AAA ATPase domain - - - 0.0002372 48.0
TLS2_k127_4596575_33 23S rRNA-intervening sequence protein - - - 0.0006535 49.0
TLS2_k127_4596575_4 N-terminal domain of unknown function (DUF4140) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 447.0
TLS2_k127_4596575_5 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 441.0
TLS2_k127_4596575_6 Flavin containing amine oxidoreductase K02293 - 1.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 420.0
TLS2_k127_4596575_7 Protein of unknown function DUF262 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 413.0
TLS2_k127_4596575_8 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 380.0
TLS2_k127_4596575_9 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 392.0
TLS2_k127_464545_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.126e-236 765.0
TLS2_k127_464545_1 PFAM TraB determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 574.0
TLS2_k127_464545_10 PS-10 peptidase S37 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 408.0
TLS2_k127_464545_11 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 366.0
TLS2_k127_464545_12 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 361.0
TLS2_k127_464545_13 Membrane K04088,K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 370.0
TLS2_k127_464545_14 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 332.0
TLS2_k127_464545_15 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 328.0
TLS2_k127_464545_16 Hsp33 protein K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 328.0
TLS2_k127_464545_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 318.0
TLS2_k127_464545_18 PilZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 301.0
TLS2_k127_464545_19 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001367 248.0
TLS2_k127_464545_2 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 535.0
TLS2_k127_464545_20 Erythromycin esterase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000001954 244.0
TLS2_k127_464545_21 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000000000000000000003812 225.0
TLS2_k127_464545_22 abc transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000005009 244.0
TLS2_k127_464545_23 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000007966 214.0
TLS2_k127_464545_24 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000006972 178.0
TLS2_k127_464545_25 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000001256 179.0
TLS2_k127_464545_26 - - - - 0.000000000000000000000000000000000000000004662 164.0
TLS2_k127_464545_27 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000000000000000000000000000000001369 166.0
TLS2_k127_464545_28 Protein conserved in bacteria K09948 - - 0.00000000000000000000000000000000000006441 143.0
TLS2_k127_464545_29 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000103 157.0
TLS2_k127_464545_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 542.0
TLS2_k127_464545_30 UbiE COQ5 methyltransferase. Source PGD - - - 0.00000000000000000000000000004244 130.0
TLS2_k127_464545_33 - - - - 0.000000000000004085 85.0
TLS2_k127_464545_35 - - - - 0.000001848 57.0
TLS2_k127_464545_36 Proteobacterial lipase chaperone protein - - - 0.000001932 61.0
TLS2_k127_464545_4 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 531.0
TLS2_k127_464545_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 509.0
TLS2_k127_464545_7 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 430.0
TLS2_k127_464545_8 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 404.0
TLS2_k127_464545_9 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 405.0
TLS2_k127_4669999_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0 1020.0
TLS2_k127_4669999_1 Helicase K17675 - 3.6.4.13 9e-323 1004.0
TLS2_k127_4669999_10 peptidyl-prolyl cis-trans isomerase activity K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 482.0
TLS2_k127_4669999_11 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 454.0
TLS2_k127_4669999_12 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 456.0
TLS2_k127_4669999_13 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 429.0
TLS2_k127_4669999_14 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 418.0
TLS2_k127_4669999_15 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 409.0
TLS2_k127_4669999_16 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 409.0
TLS2_k127_4669999_17 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 409.0
TLS2_k127_4669999_18 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 347.0
TLS2_k127_4669999_19 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 325.0
TLS2_k127_4669999_2 protein kinase activity - - - 5.545e-248 785.0
TLS2_k127_4669999_20 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000006077 258.0
TLS2_k127_4669999_22 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000569 224.0
TLS2_k127_4669999_24 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000002156 169.0
TLS2_k127_4669999_25 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000007197 172.0
TLS2_k127_4669999_26 - - - - 0.0000000000000000000000000000000000000001178 156.0
TLS2_k127_4669999_28 - - - - 0.000000000000000000000000000000000000004254 151.0
TLS2_k127_4669999_30 COG3267 Type II secretory pathway, component ExeA K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00005258 49.0
TLS2_k127_4669999_4 Rod shape-determining protein K03569 - - 1.815e-208 651.0
TLS2_k127_4669999_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 614.0
TLS2_k127_4669999_6 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 593.0
TLS2_k127_4669999_7 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 565.0
TLS2_k127_4669999_8 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00015,K03778 - 1.1.1.26,1.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 491.0
TLS2_k127_4669999_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 509.0
TLS2_k127_4700979_0 Tetratricopeptide repeat - - - 0.0 1404.0
TLS2_k127_4700979_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0 1135.0
TLS2_k127_4700979_10 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 543.0
TLS2_k127_4700979_11 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 531.0
TLS2_k127_4700979_12 energy transducer activity K03832,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 522.0
TLS2_k127_4700979_13 PFAM Metal-dependent phosphohydrolase, HD K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 480.0
TLS2_k127_4700979_14 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 442.0
TLS2_k127_4700979_15 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 437.0
TLS2_k127_4700979_16 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 421.0
TLS2_k127_4700979_17 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 398.0
TLS2_k127_4700979_18 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 412.0
TLS2_k127_4700979_19 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 383.0
TLS2_k127_4700979_2 Elongation factor G, domain IV K02355 - - 0.0 1112.0
TLS2_k127_4700979_20 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 357.0
TLS2_k127_4700979_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 327.0
TLS2_k127_4700979_23 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 311.0
TLS2_k127_4700979_24 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 311.0
TLS2_k127_4700979_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 295.0
TLS2_k127_4700979_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007152 273.0
TLS2_k127_4700979_27 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000435 261.0
TLS2_k127_4700979_29 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000009258 246.0
TLS2_k127_4700979_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1039.0
TLS2_k127_4700979_30 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000002944 241.0
TLS2_k127_4700979_32 Rare lipoprotein A (RlpA)-like double-psi beta-barrel K20628 - - 0.000000000000000000000000000000000000000000000000000000000000001061 228.0
TLS2_k127_4700979_33 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.000000000000000000000000000000000000000000000000000000000000003777 231.0
TLS2_k127_4700979_34 response regulator K02282,K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000005355 229.0
TLS2_k127_4700979_35 protein heterodimerization activity - - - 0.000000000000000000000000000000000000000000000000000000001032 208.0
TLS2_k127_4700979_36 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000001196 203.0
TLS2_k127_4700979_37 IMP dehydrogenase activity K04767 - - 0.000000000000000000000000000000000000000000000000000000001359 212.0
TLS2_k127_4700979_4 protein trimerization K06894,K07114 - - 1.363e-242 780.0
TLS2_k127_4700979_40 bacterial-type flagellum organization K02411 - - 0.000000000000000000000000000000000000000003138 167.0
TLS2_k127_4700979_41 PFAM Major facilitator superfamily - - - 0.00000000000000000000000000000000000005455 163.0
TLS2_k127_4700979_42 nitrite reductase [NAD(P)H] activity K14952 - - 0.000000000000000000000000000000000001135 146.0
TLS2_k127_4700979_43 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000006591 100.0
TLS2_k127_4700979_46 Electron transfer flavoprotein domain K03521 - - 0.00000000001972 76.0
TLS2_k127_4700979_47 Nucleotidyltransferase - - - 0.00000000004487 66.0
TLS2_k127_4700979_48 bacterial-type flagellum organization K02411 - - 0.0000007096 59.0
TLS2_k127_4700979_5 sigma54 specific, transcriptional regulator, Fis family - - - 1.982e-234 731.0
TLS2_k127_4700979_6 Family membership K08884,K12132 - 2.7.11.1 5.905e-212 674.0
TLS2_k127_4700979_7 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 1.392e-201 642.0
TLS2_k127_4700979_8 succinate-CoA ligase activity - - - 1.451e-199 645.0
TLS2_k127_4700979_9 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 550.0
TLS2_k127_4705926_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0 1424.0
TLS2_k127_4705926_1 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster - - - 0.0 1295.0
TLS2_k127_4705926_10 metal cluster binding K06940,K18475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 563.0
TLS2_k127_4705926_11 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 558.0
TLS2_k127_4705926_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 538.0
TLS2_k127_4705926_13 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 518.0
TLS2_k127_4705926_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 466.0
TLS2_k127_4705926_15 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 440.0
TLS2_k127_4705926_16 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 439.0
TLS2_k127_4705926_17 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 399.0
TLS2_k127_4705926_18 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 367.0
TLS2_k127_4705926_19 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 346.0
TLS2_k127_4705926_2 SMART serine threonine protein kinase - - - 0.0 1107.0
TLS2_k127_4705926_20 May be involved in recombination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 330.0
TLS2_k127_4705926_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 331.0
TLS2_k127_4705926_22 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 316.0
TLS2_k127_4705926_23 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 310.0
TLS2_k127_4705926_25 PLD-like domain K17717 - 3.1.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001871 291.0
TLS2_k127_4705926_26 Putative transposase, YhgA-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004195 278.0
TLS2_k127_4705926_27 Psort location Cytoplasmic, score K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000001138 284.0
TLS2_k127_4705926_28 Putative exonuclease, RdgC K03554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002422 259.0
TLS2_k127_4705926_29 Signal transduction histidine kinase K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004165 271.0
TLS2_k127_4705926_3 Peptidase inhibitor I9 K20754 - 3.4.21.111 1.396e-296 931.0
TLS2_k127_4705926_31 glutamate-tRNA ligase activity K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000356 229.0
TLS2_k127_4705926_32 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000106 223.0
TLS2_k127_4705926_33 - - - - 0.0000000000000000000000000000000000000000000000000000000001062 209.0
TLS2_k127_4705926_34 FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000004591 220.0
TLS2_k127_4705926_35 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000001187 200.0
TLS2_k127_4705926_36 tRNA cytidylyltransferase activity - - - 0.00000000000000000000000000000000000000000000000005479 190.0
TLS2_k127_4705926_37 PFAM Annexin repeat - - - 0.0000000000000000000000000000000000000000000001278 193.0
TLS2_k127_4705926_39 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000009812 165.0
TLS2_k127_4705926_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 3.874e-208 658.0
TLS2_k127_4705926_41 - - - - 0.000000000000000000000000004037 119.0
TLS2_k127_4705926_43 - - - - 0.0000000000000000003167 103.0
TLS2_k127_4705926_44 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000005158 88.0
TLS2_k127_4705926_45 - - - - 0.0000000000000000108 98.0
TLS2_k127_4705926_47 CpXC protein - - - 0.0000000000000001187 90.0
TLS2_k127_4705926_48 - - - - 0.000000000000002021 85.0
TLS2_k127_4705926_49 Putative transposase, YhgA-like - - - 0.000000000000855 72.0
TLS2_k127_4705926_5 AAA domain (dynein-related subfamily) - - - 2.618e-206 667.0
TLS2_k127_4705926_50 deoxyhypusine monooxygenase activity - - - 0.00000000003639 74.0
TLS2_k127_4705926_51 - - - - 0.0000000001082 76.0
TLS2_k127_4705926_52 Nuclease-related domain - - - 0.00000002519 68.0
TLS2_k127_4705926_53 Outer membrane protein protective antigen OMA87 K07277 - - 0.000001608 61.0
TLS2_k127_4705926_54 pilus organization - - - 0.0001699 55.0
TLS2_k127_4705926_6 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 627.0
TLS2_k127_4705926_7 Type II restriction enzyme, methylase subunits - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 637.0
TLS2_k127_4705926_8 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 587.0
TLS2_k127_4705926_9 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 581.0
TLS2_k127_4749813_0 Aerotolerance regulator N-terminal - - - 8.081e-286 908.0
TLS2_k127_4749813_1 ATPase associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 557.0
TLS2_k127_4749813_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 281.0
TLS2_k127_4749813_3 SMART Integrin alpha beta-propellor repeat protein - - - 0.0000000000000000000000000000000000357 146.0
TLS2_k127_4749813_4 double-stranded DNA endodeoxyribonuclease activity - - - 0.000000000009154 69.0
TLS2_k127_4749813_5 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000001683 72.0
TLS2_k127_4749813_6 Domain of unknown function (DUF2019) - - - 0.0000005596 56.0
TLS2_k127_4749813_7 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000002731 53.0
TLS2_k127_4791702_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 535.0
TLS2_k127_4791702_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 472.0
TLS2_k127_4791702_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006932 243.0
TLS2_k127_4791702_5 Helix-hairpin-helix motif K02237 - - 0.0000000000000000000000000006517 120.0
TLS2_k127_4801983_0 Peptidase dimerisation domain - - - 9.761e-225 706.0
TLS2_k127_4801983_1 PFAM OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 601.0
TLS2_k127_4801983_2 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.00000000000000000000000000000000000000000000001361 181.0
TLS2_k127_4836745_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1168.0
TLS2_k127_4836745_1 cell adhesion involved in biofilm formation - - - 8.399e-318 988.0
TLS2_k127_4836745_10 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 574.0
TLS2_k127_4836745_11 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 515.0
TLS2_k127_4836745_12 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 515.0
TLS2_k127_4836745_13 Pfam:Kce - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 488.0
TLS2_k127_4836745_14 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 492.0
TLS2_k127_4836745_15 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 456.0
TLS2_k127_4836745_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 460.0
TLS2_k127_4836745_17 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 401.0
TLS2_k127_4836745_18 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 403.0
TLS2_k127_4836745_19 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 396.0
TLS2_k127_4836745_2 Type II and III secretion system protein K02453 - - 2.492e-303 949.0
TLS2_k127_4836745_20 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 399.0
TLS2_k127_4836745_21 General secretion pathway protein C K02452 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 366.0
TLS2_k127_4836745_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 369.0
TLS2_k127_4836745_23 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 356.0
TLS2_k127_4836745_24 COG1985 Pyrimidine reductase, riboflavin biosynthesis K00082,K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 325.0
TLS2_k127_4836745_25 Type II secretion system (T2SS), protein J K02459 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 314.0
TLS2_k127_4836745_26 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 315.0
TLS2_k127_4836745_27 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 302.0
TLS2_k127_4836745_29 Helix-hairpin-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001773 308.0
TLS2_k127_4836745_3 HsdM N-terminal domain K03427 - 2.1.1.72 3.063e-271 857.0
TLS2_k127_4836745_30 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001112 279.0
TLS2_k127_4836745_31 general secretion pathway protein K02456,K10927,K12285 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001237 277.0
TLS2_k127_4836745_34 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002208 257.0
TLS2_k127_4836745_35 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001344 260.0
TLS2_k127_4836745_37 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000008946 224.0
TLS2_k127_4836745_38 spore germination - - - 0.00000000000000000000000000000000000000000000000000000001709 209.0
TLS2_k127_4836745_39 Prokaryotic N-terminal methylation motif K02458 - - 0.00000000000000000000000000000000000000000000000000001401 207.0
TLS2_k127_4836745_4 Alpha-amylase domain K01182,K01187 - 3.2.1.10,3.2.1.20 9.907e-248 779.0
TLS2_k127_4836745_40 PFAM Thioredoxin domain K05838 - - 0.00000000000000000000000000000000000000000000000000002147 200.0
TLS2_k127_4836745_41 General secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000001471 177.0
TLS2_k127_4836745_43 6-pyruvoyl tetrahydropterin synthase - - - 0.000000000000000000000000000000000000000000002511 167.0
TLS2_k127_4836745_44 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000001127 165.0
TLS2_k127_4836745_47 - - - - 0.00000000000000000000002339 113.0
TLS2_k127_4836745_48 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000006886 106.0
TLS2_k127_4836745_49 - - - - 0.0000000000000000005388 102.0
TLS2_k127_4836745_5 response regulator K07713 - - 1.082e-238 746.0
TLS2_k127_4836745_51 - - - - 0.0000000001881 62.0
TLS2_k127_4836745_52 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000003487 59.0
TLS2_k127_4836745_54 30S ribosomal protein S23 - - - 0.000001418 56.0
TLS2_k127_4836745_55 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0003856 53.0
TLS2_k127_4836745_6 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 8.851e-197 632.0
TLS2_k127_4836745_7 General secretion pathway protein F K02455,K02653 - - 9.519e-195 614.0
TLS2_k127_4836745_8 Type IV pilus assembly protein PilM; K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 609.0
TLS2_k127_4836745_9 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 630.0
TLS2_k127_4846415_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 5.523e-243 758.0
TLS2_k127_4846415_1 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 551.0
TLS2_k127_4846415_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 422.0
TLS2_k127_4846415_3 Periplasmic binding protein domain K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 396.0
TLS2_k127_4846415_4 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 385.0
TLS2_k127_4846415_5 protein secretion by the type VII secretion system - - - 0.000001606 59.0
TLS2_k127_4846415_6 - - - - 0.000683 49.0
TLS2_k127_497800_0 Sigma-54 interaction domain K02584 - - 0.0 1017.0
TLS2_k127_497800_1 oligopeptide transporter opt family - - - 4.044e-266 836.0
TLS2_k127_497800_10 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001662 284.0
TLS2_k127_497800_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001028 281.0
TLS2_k127_497800_12 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000006342 254.0
TLS2_k127_497800_14 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.0000000000000000000000000000000000000000001107 164.0
TLS2_k127_497800_15 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000004656 175.0
TLS2_k127_497800_16 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000000216 123.0
TLS2_k127_497800_17 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000005918 107.0
TLS2_k127_497800_18 Polymer-forming cytoskeletal - - - 0.00000000000000007069 87.0
TLS2_k127_497800_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.179e-243 760.0
TLS2_k127_497800_3 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 490.0
TLS2_k127_497800_4 Alkaline phosphatase with broad substrate specificity K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 490.0
TLS2_k127_497800_5 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 412.0
TLS2_k127_497800_6 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 405.0
TLS2_k127_497800_7 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 362.0
TLS2_k127_497800_9 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 282.0
TLS2_k127_5007312_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1028.0
TLS2_k127_5007312_1 SMART DNA-directed DNA polymerase B - - - 1.698e-315 986.0
TLS2_k127_5007312_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 474.0
TLS2_k127_5007312_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 439.0
TLS2_k127_5007312_12 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 396.0
TLS2_k127_5007312_13 Protein of unknown function (DUF3445) K22342 - 1.14.13.238 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 340.0
TLS2_k127_5007312_14 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 318.0
TLS2_k127_5007312_15 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 292.0
TLS2_k127_5007312_16 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001598 266.0
TLS2_k127_5007312_17 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000001518 230.0
TLS2_k127_5007312_18 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000008987 226.0
TLS2_k127_5007312_19 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000003576 216.0
TLS2_k127_5007312_2 COG0208 Ribonucleotide reductase, beta subunit - - - 2.964e-206 649.0
TLS2_k127_5007312_21 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000000000000000000001565 212.0
TLS2_k127_5007312_22 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000243 202.0
TLS2_k127_5007312_23 PelD GGDEF domain K21009 - - 0.000000000000000000000000000000000000000000000001719 187.0
TLS2_k127_5007312_24 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000002948 168.0
TLS2_k127_5007312_25 Heme oxygenase - - - 0.00000000000000000000000000000000000007866 151.0
TLS2_k127_5007312_27 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000001168 145.0
TLS2_k127_5007312_28 lyase activity K21010 - - 0.000000000000000000000000000002176 135.0
TLS2_k127_5007312_29 Cupin domain - - - 0.000000000000000000000000000005055 126.0
TLS2_k127_5007312_3 Domain of unknown function (DUF3492) K20921,K21011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 614.0
TLS2_k127_5007312_30 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000002313 112.0
TLS2_k127_5007312_31 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.00000000000000000004457 100.0
TLS2_k127_5007312_33 Response regulator, receiver - - - 0.00000000000000001481 94.0
TLS2_k127_5007312_35 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000451 67.0
TLS2_k127_5007312_37 RepB plasmid partitioning protein K03497 - - 0.000000005631 67.0
TLS2_k127_5007312_38 SEC-C motif - - - 0.000000006512 61.0
TLS2_k127_5007312_39 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00001145 50.0
TLS2_k127_5007312_4 Flavin-binding monooxygenase-like K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 565.0
TLS2_k127_5007312_40 ABC transporter related - - - 0.0002944 52.0
TLS2_k127_5007312_41 COG0457 FOG TPR repeat K21007 - - 0.0007187 53.0
TLS2_k127_5007312_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 531.0
TLS2_k127_5007312_6 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 527.0
TLS2_k127_5007312_7 PFAM TM1410 hypothetical-related protein K21006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 533.0
TLS2_k127_5007312_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 470.0
TLS2_k127_5007312_9 Putative exopolysaccharide Exporter (EPS-E) K21012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 448.0
TLS2_k127_5009534_0 Aminotransferase class-III K03918 - 2.6.1.36 0.0 1915.0
TLS2_k127_5009534_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1446.0
TLS2_k127_5009534_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 1.234e-199 632.0
TLS2_k127_5009534_11 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 630.0
TLS2_k127_5009534_12 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 589.0
TLS2_k127_5009534_13 COG2059 Chromate transport protein ChrA K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 582.0
TLS2_k127_5009534_14 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 597.0
TLS2_k127_5009534_15 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 560.0
TLS2_k127_5009534_16 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 545.0
TLS2_k127_5009534_17 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 550.0
TLS2_k127_5009534_18 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 516.0
TLS2_k127_5009534_19 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 490.0
TLS2_k127_5009534_2 Family membership - - - 0.0 1332.0
TLS2_k127_5009534_20 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 425.0
TLS2_k127_5009534_21 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 431.0
TLS2_k127_5009534_22 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 415.0
TLS2_k127_5009534_23 TIGRFAM CRISPR-associated protein, APE2256 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 404.0
TLS2_k127_5009534_24 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 412.0
TLS2_k127_5009534_25 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 405.0
TLS2_k127_5009534_26 diaminopimelate decarboxylase activity K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 396.0
TLS2_k127_5009534_27 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 387.0
TLS2_k127_5009534_28 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 345.0
TLS2_k127_5009534_29 Belongs to the peptidase S11 family K01286,K07258,K07262 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 338.0
TLS2_k127_5009534_3 Dienelactone hydrolase family - - - 8.783e-287 897.0
TLS2_k127_5009534_30 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 332.0
TLS2_k127_5009534_31 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 328.0
TLS2_k127_5009534_32 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 327.0
TLS2_k127_5009534_33 metallopeptidase activity K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 322.0
TLS2_k127_5009534_34 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 302.0
TLS2_k127_5009534_35 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 296.0
TLS2_k127_5009534_36 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001321 282.0
TLS2_k127_5009534_37 iodide peroxidase activity K17231 GO:0000166,GO:0003674,GO:0003824,GO:0004447,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006570,GO:0006575,GO:0006590,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009072,GO:0009636,GO:0009987,GO:0010181,GO:0010817,GO:0012506,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0018958,GO:0019752,GO:0030659,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0032553,GO:0036094,GO:0042221,GO:0042403,GO:0042445,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071704,GO:0071944,GO:0097159,GO:0097237,GO:0097367,GO:0097708,GO:0098754,GO:0098869,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901605,GO:1901615,GO:1990748 1.21.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001278 283.0
TLS2_k127_5009534_38 Protein of unknown function (DUF3050) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003174 276.0
TLS2_k127_5009534_39 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003793 301.0
TLS2_k127_5009534_4 SMART protein phosphatase 2C domain protein - - - 6.378e-259 815.0
TLS2_k127_5009534_40 Ramp superfamily protein probably involved in dna repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006032 273.0
TLS2_k127_5009534_41 defense response to virus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001038 273.0
TLS2_k127_5009534_43 PGAP1-like protein K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000007396 244.0
TLS2_k127_5009534_44 - - - - 0.00000000000000000000000000000000000000000000000000000000000000009357 235.0
TLS2_k127_5009534_45 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001301 233.0
TLS2_k127_5009534_46 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000003186 228.0
TLS2_k127_5009534_47 metallopeptidase activity K03592 - - 0.0000000000000000000000000000000000000000000000000000000000005158 234.0
TLS2_k127_5009534_48 crispr-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000002902 230.0
TLS2_k127_5009534_49 PFAM Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000004778 201.0
TLS2_k127_5009534_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.476e-258 799.0
TLS2_k127_5009534_50 heme binding K21472 - - 0.0000000000000000000000000000000000000000000000000001342 194.0
TLS2_k127_5009534_51 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000003401 191.0
TLS2_k127_5009534_52 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000001823 192.0
TLS2_k127_5009534_53 - - - - 0.0000000000000000000000000000000000000000000005138 177.0
TLS2_k127_5009534_54 Protein of unknown function (DUF1360) - - - 0.000000000000000000000000000000000000004286 155.0
TLS2_k127_5009534_55 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000001611 158.0
TLS2_k127_5009534_56 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000004496 141.0
TLS2_k127_5009534_57 Ramp superfamily protein probably involved in dna repair - - - 0.00000000000000000000000000000000003987 147.0
TLS2_k127_5009534_58 TIGRFAM CRISPR-associated RAMP protein, Csx10 family K19134 - - 0.0000000000000000000000000000000008948 149.0
TLS2_k127_5009534_59 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000003262 147.0
TLS2_k127_5009534_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.914e-256 842.0
TLS2_k127_5009534_61 - - - - 0.000000000000000000000000000000006372 143.0
TLS2_k127_5009534_62 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000001861 132.0
TLS2_k127_5009534_63 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000004064 122.0
TLS2_k127_5009534_64 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000402 133.0
TLS2_k127_5009534_65 Bacterial PH domain - - - 0.000000000000000000000000007807 124.0
TLS2_k127_5009534_66 Transposase IS66 family K07484 - - 0.000000000000000000000001635 106.0
TLS2_k127_5009534_68 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000006211 108.0
TLS2_k127_5009534_69 metal cluster binding K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.0000000000000000002174 96.0
TLS2_k127_5009534_7 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 3.198e-252 789.0
TLS2_k127_5009534_70 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000001468 86.0
TLS2_k127_5009534_71 cell adhesion involved in biofilm formation - - - 0.00000000000005355 79.0
TLS2_k127_5009534_72 Butirosin biosynthesis protein H, N-terminal - - - 0.0000000001507 73.0
TLS2_k127_5009534_75 TIGRFAM CRISPR-associated protein, TIGR03984 family - - - 0.0000004293 59.0
TLS2_k127_5009534_76 - - - - 0.0000136 50.0
TLS2_k127_5009534_78 Belongs to the 'phage' integrase family K14059 - - 0.0003847 46.0
TLS2_k127_5009534_8 single-stranded-DNA-specific exonuclease RecJ K07462 - - 1.285e-229 723.0
TLS2_k127_5009534_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 4.584e-211 687.0
TLS2_k127_5024775_0 SMART serine threonine protein kinase K12132 - 2.7.11.1 3.533e-274 878.0
TLS2_k127_5024775_1 Sulfatase-modifying factor enzyme 1 - - - 1.159e-203 679.0
TLS2_k127_5024775_11 double-stranded DNA endodeoxyribonuclease activity - - - 0.0000000000007462 70.0
TLS2_k127_5024775_13 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.0004951 53.0
TLS2_k127_5024775_2 negative regulation of transforming growth factor beta1 production K03068,K06261,K06593,K08867,K09187,K12488,K13738,K14972,K20050,K20371 GO:0000003,GO:0001654,GO:0001667,GO:0001745,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005938,GO:0006928,GO:0006996,GO:0007010,GO:0007015,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007423,GO:0008150,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010564,GO:0010631,GO:0016020,GO:0016043,GO:0016477,GO:0017124,GO:0019904,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0030029,GO:0030036,GO:0030100,GO:0030154,GO:0030496,GO:0030707,GO:0030855,GO:0032153,GO:0032154,GO:0032155,GO:0032465,GO:0032501,GO:0032502,GO:0032504,GO:0032794,GO:0032879,GO:0034329,GO:0034330,GO:0034332,GO:0034333,GO:0040011,GO:0043062,GO:0043063,GO:0044085,GO:0044421,GO:0044424,GO:0044425,GO:0044444,GO:0044448,GO:0044459,GO:0044464,GO:0044703,GO:0045171,GO:0045177,GO:0045179,GO:0045216,GO:0045807,GO:0048259,GO:0048260,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048592,GO:0048609,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050794,GO:0050839,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051179,GO:0051302,GO:0051674,GO:0051704,GO:0051726,GO:0060429,GO:0060627,GO:0065007,GO:0071840,GO:0071944,GO:0090130,GO:0090132,GO:0090596,GO:0097435,GO:0098590,GO:0099568,GO:0099738 2.1.1.43,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 372.0
TLS2_k127_5024775_3 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003221 243.0
TLS2_k127_5024775_4 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000004187 241.0
TLS2_k127_5024775_5 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000002969 232.0
TLS2_k127_5024775_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000001077 180.0
TLS2_k127_5024775_7 ECF sigma factor - - - 0.00000000000000000000000000000000000000000008055 166.0
TLS2_k127_5024775_8 Homologues of snake disintegrins - - - 0.000000000000000000000000000008297 135.0
TLS2_k127_5024775_9 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.000000000000000000001817 107.0
TLS2_k127_5054227_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1350.0
TLS2_k127_5054227_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.115e-319 997.0
TLS2_k127_5054227_10 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 548.0
TLS2_k127_5054227_11 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 531.0
TLS2_k127_5054227_12 chorismate binding enzyme K01851,K02361,K02552 - 5.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 515.0
TLS2_k127_5054227_13 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 476.0
TLS2_k127_5054227_15 Lamin Tail Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 470.0
TLS2_k127_5054227_16 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 448.0
TLS2_k127_5054227_17 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 425.0
TLS2_k127_5054227_18 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 449.0
TLS2_k127_5054227_19 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 417.0
TLS2_k127_5054227_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.638e-257 801.0
TLS2_k127_5054227_20 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 400.0
TLS2_k127_5054227_21 metallopeptidase MepB K01405,K13726 GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005773,GO:0005794,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0012505,GO:0016787,GO:0019538,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043603,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070011,GO:0070013,GO:0071704,GO:0140096,GO:1901564 3.4.24.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 385.0
TLS2_k127_5054227_22 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 346.0
TLS2_k127_5054227_23 Ectoine hydroxylase K10674 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.11.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 349.0
TLS2_k127_5054227_24 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 341.0
TLS2_k127_5054227_25 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 335.0
TLS2_k127_5054227_26 COG1126 ABC-type polar amino acid transport system, ATPase component K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 323.0
TLS2_k127_5054227_27 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 310.0
TLS2_k127_5054227_28 polar amino acid ABC transporter, inner membrane subunit K02029,K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 287.0
TLS2_k127_5054227_3 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 3.282e-224 735.0
TLS2_k127_5054227_30 Protein of unknown function (DUF790) K09744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002993 294.0
TLS2_k127_5054227_31 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001178 282.0
TLS2_k127_5054227_32 polar amino acid ABC transporter, inner membrane subunit K02029,K10037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007247 247.0
TLS2_k127_5054227_33 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003589 253.0
TLS2_k127_5054227_34 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000002747 249.0
TLS2_k127_5054227_36 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000002436 228.0
TLS2_k127_5054227_37 PFAM SEC-C motif domain protein K09858 - - 0.000000000000000000000000000000000000000000000000000000004838 203.0
TLS2_k127_5054227_38 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.000000000000000000000000000000000000000000000000000001146 196.0
TLS2_k127_5054227_39 glycerophosphoryl diester phosphodiesterase K01113,K01126 - 3.1.3.1,3.1.4.46 0.0000000000000000000000000000000000000000000000000000165 214.0
TLS2_k127_5054227_4 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 3.128e-221 704.0
TLS2_k127_5054227_40 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000001488 208.0
TLS2_k127_5054227_41 L-2,4-diaminobutyric acid acetyltransferase K06718 - 2.3.1.178 0.00000000000000000000000000000000000000000000005606 177.0
TLS2_k127_5054227_42 PFAM Mo-dependent nitrogenase K05793 - - 0.0000000000000000000000000000000000000000000008083 169.0
TLS2_k127_5054227_43 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000198 161.0
TLS2_k127_5054227_44 Subtilase family - - - 0.00000000000000000000000000000000000006712 166.0
TLS2_k127_5054227_45 GYD domain - - - 0.00000000000000000000000000000000001745 139.0
TLS2_k127_5054227_46 translation initiation factor activity K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000009029 126.0
TLS2_k127_5054227_47 Putative transposase, YhgA-like - - - 0.000000000000000000001215 104.0
TLS2_k127_5054227_48 RadC-like JAB domain K03630 - - 0.00000000000000000003891 97.0
TLS2_k127_5054227_49 Transcriptional regulator K13640 - - 0.0000000000000001524 85.0
TLS2_k127_5054227_5 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 5.662e-216 680.0
TLS2_k127_5054227_51 transmembrane signaling receptor activity K03406 - - 0.0000000347 58.0
TLS2_k127_5054227_52 Peptidase family M48 - - - 0.0003683 45.0
TLS2_k127_5054227_6 SNF2 family N-terminal domain - - - 4.447e-205 647.0
TLS2_k127_5054227_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 617.0
TLS2_k127_5054227_8 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 636.0
TLS2_k127_5054227_9 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 581.0
TLS2_k127_5108735_0 Family membership - - - 0.0 1503.0
TLS2_k127_5108735_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.766e-237 746.0
TLS2_k127_5108735_10 - - - - 0.00000000000000000000000000000000000000000002045 166.0
TLS2_k127_5108735_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000004592 154.0
TLS2_k127_5108735_12 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000001481 137.0
TLS2_k127_5108735_13 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000005365 139.0
TLS2_k127_5108735_14 bacterial-type flagellum organization K02411 - - 0.0000000000000000000002547 103.0
TLS2_k127_5108735_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 535.0
TLS2_k127_5108735_3 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 485.0
TLS2_k127_5108735_4 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 440.0
TLS2_k127_5108735_5 Protein serine threonine phosphatase K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 413.0
TLS2_k127_5108735_6 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 371.0
TLS2_k127_5108735_7 FCD K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 359.0
TLS2_k127_5108735_8 guanyl-nucleotide exchange factor activity K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004805 287.0
TLS2_k127_5108735_9 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002088 274.0
TLS2_k127_5121394_0 Baseplate J-like protein - - - 0.0 1611.0
TLS2_k127_5121394_1 Oligoendopeptidase f - - - 1.689e-320 998.0
TLS2_k127_5121394_11 Phage late control gene D protein (GPD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 529.0
TLS2_k127_5121394_12 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 532.0
TLS2_k127_5121394_13 Phage tail protein (Tail_P2_I) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 495.0
TLS2_k127_5121394_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 480.0
TLS2_k127_5121394_15 phosphatase K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 466.0
TLS2_k127_5121394_16 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 469.0
TLS2_k127_5121394_17 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07714,K10941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 455.0
TLS2_k127_5121394_18 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 416.0
TLS2_k127_5121394_19 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 400.0
TLS2_k127_5121394_2 tail sheath protein K06907 - - 1.897e-304 941.0
TLS2_k127_5121394_20 Rhs element vgr protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 352.0
TLS2_k127_5121394_21 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 363.0
TLS2_k127_5121394_23 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 338.0
TLS2_k127_5121394_24 histone H2A K63-linked ubiquitination K16922 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 322.0
TLS2_k127_5121394_26 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 327.0
TLS2_k127_5121394_27 protein homooligomerization K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 308.0
TLS2_k127_5121394_28 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 299.0
TLS2_k127_5121394_29 Rhs element Vgr protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001515 299.0
TLS2_k127_5121394_3 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 1.358e-279 866.0
TLS2_k127_5121394_30 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
TLS2_k127_5121394_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003468 247.0
TLS2_k127_5121394_33 Protein of unknown function (DUF1257) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003428 241.0
TLS2_k127_5121394_34 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002244 240.0
TLS2_k127_5121394_35 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000279 217.0
TLS2_k127_5121394_36 PFAM Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000002443 221.0
TLS2_k127_5121394_37 LysM domain - - - 0.000000000000000000000000000000000000000000000000004382 185.0
TLS2_k127_5121394_4 - - - - 1.095e-266 827.0
TLS2_k127_5121394_40 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000001624 183.0
TLS2_k127_5121394_42 ATP synthesis coupled proton transport K02109 - - 0.000000000000000000000000000000000000000000004623 169.0
TLS2_k127_5121394_43 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000005275 157.0
TLS2_k127_5121394_44 Ferredoxin - - - 0.00000000000000000000000000000000000003398 146.0
TLS2_k127_5121394_45 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.0000000000000000000000000000000000005461 145.0
TLS2_k127_5121394_46 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000003467 149.0
TLS2_k127_5121394_47 Protein of unknown function (DUF2997) - - - 0.000000000000000000000000002382 111.0
TLS2_k127_5121394_48 - - - - 0.00000000000000000000000002223 124.0
TLS2_k127_5121394_49 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000002628 110.0
TLS2_k127_5121394_5 tail sheath protein K06907 - - 1.258e-252 781.0
TLS2_k127_5121394_51 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000007631 80.0
TLS2_k127_5121394_52 COG0433 Predicted ATPase - - - 0.000000000000001802 84.0
TLS2_k127_5121394_53 - - - - 0.00000000001231 74.0
TLS2_k127_5121394_6 cell wall organization K01768 - 4.6.1.1 6.232e-213 687.0
TLS2_k127_5121394_7 lysine 2,3-aminomutase K01843 - 5.4.3.2 5.732e-199 627.0
TLS2_k127_5121394_8 histone H2A K63-linked ubiquitination K07169,K08884,K11894,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 591.0
TLS2_k127_5124865_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1516.0
TLS2_k127_5124865_1 cytochrome C peroxidase - - - 0.0 1260.0
TLS2_k127_5124865_10 Spore coat protein CotH - - - 2.613e-238 761.0
TLS2_k127_5124865_100 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000005855 98.0
TLS2_k127_5124865_101 MORN repeat variant - - - 0.00000000000000000002013 106.0
TLS2_k127_5124865_103 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.0000000000000001292 88.0
TLS2_k127_5124865_105 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000005317 70.0
TLS2_k127_5124865_107 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000003207 78.0
TLS2_k127_5124865_108 Hemerythrin HHE cation binding domain - - - 0.0000000006728 68.0
TLS2_k127_5124865_109 Putative addiction module component - - - 0.00000002977 59.0
TLS2_k127_5124865_11 His Kinase A (phosphoacceptor) domain - - - 2.602e-235 755.0
TLS2_k127_5124865_110 Fe2 -dicitrate sensor, membrane component K07165 - - 0.0000009054 61.0
TLS2_k127_5124865_111 Hemerythrin HHE cation binding domain protein - - - 0.00000116 59.0
TLS2_k127_5124865_112 - - - - 0.000001368 63.0
TLS2_k127_5124865_113 rnps1,sr45 K14325 GO:0000375,GO:0000377,GO:0000398,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008380,GO:0009743,GO:0009756,GO:0009987,GO:0010033,GO:0010182,GO:0010467,GO:0016070,GO:0016071,GO:0016604,GO:0016607,GO:0023052,GO:0031974,GO:0031981,GO:0034641,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070013,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:0090304,GO:1901360,GO:1901700,GO:1901701 - 0.00003421 55.0
TLS2_k127_5124865_12 Serine Threonine protein kinase - - - 7.361e-232 762.0
TLS2_k127_5124865_13 Belongs to the UPF0229 family K09786 - - 9.337e-217 679.0
TLS2_k127_5124865_14 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 2.616e-204 644.0
TLS2_k127_5124865_15 ABC-type transport system involved in lipoprotein release permease component K09808 - - 2.583e-201 639.0
TLS2_k127_5124865_16 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 4.213e-199 641.0
TLS2_k127_5124865_17 PFAM Pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 1.971e-195 631.0
TLS2_k127_5124865_18 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 640.0
TLS2_k127_5124865_19 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 589.0
TLS2_k127_5124865_2 PrkA AAA domain K07180 - - 0.0 1257.0
TLS2_k127_5124865_20 Flavin-binding monooxygenase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 572.0
TLS2_k127_5124865_21 PFAM sigma-54 factor interaction domain-containing protein K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 554.0
TLS2_k127_5124865_22 Cobalamin biosynthesis protein CobT VWA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 561.0
TLS2_k127_5124865_23 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 535.0
TLS2_k127_5124865_24 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 543.0
TLS2_k127_5124865_25 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 529.0
TLS2_k127_5124865_26 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 509.0
TLS2_k127_5124865_27 Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 511.0
TLS2_k127_5124865_28 PrpF protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 467.0
TLS2_k127_5124865_29 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 453.0
TLS2_k127_5124865_3 aconitate hydratase K01681 - 4.2.1.3 0.0 1160.0
TLS2_k127_5124865_30 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 462.0
TLS2_k127_5124865_31 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 457.0
TLS2_k127_5124865_32 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 449.0
TLS2_k127_5124865_33 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 464.0
TLS2_k127_5124865_34 cysteine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 442.0
TLS2_k127_5124865_35 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 435.0
TLS2_k127_5124865_36 ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 430.0
TLS2_k127_5124865_37 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 417.0
TLS2_k127_5124865_38 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 422.0
TLS2_k127_5124865_39 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 409.0
TLS2_k127_5124865_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0 1024.0
TLS2_k127_5124865_40 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 391.0
TLS2_k127_5124865_41 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 402.0
TLS2_k127_5124865_42 PFAM ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 403.0
TLS2_k127_5124865_43 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 389.0
TLS2_k127_5124865_44 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 381.0
TLS2_k127_5124865_45 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 366.0
TLS2_k127_5124865_46 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 363.0
TLS2_k127_5124865_47 phosphosulfolactate synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 363.0
TLS2_k127_5124865_48 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 357.0
TLS2_k127_5124865_49 COG4584 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 361.0
TLS2_k127_5124865_5 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 8.81e-308 983.0
TLS2_k127_5124865_51 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 359.0
TLS2_k127_5124865_52 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 352.0
TLS2_k127_5124865_53 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 361.0
TLS2_k127_5124865_54 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 338.0
TLS2_k127_5124865_55 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 332.0
TLS2_k127_5124865_57 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 336.0
TLS2_k127_5124865_58 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 330.0
TLS2_k127_5124865_59 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 317.0
TLS2_k127_5124865_6 Penicillin amidase K01434 - 3.5.1.11 7.409e-289 915.0
TLS2_k127_5124865_60 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 338.0
TLS2_k127_5124865_61 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 316.0
TLS2_k127_5124865_62 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 312.0
TLS2_k127_5124865_64 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 305.0
TLS2_k127_5124865_65 Pregnancy-associated plasma protein-A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 308.0
TLS2_k127_5124865_66 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 302.0
TLS2_k127_5124865_67 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 302.0
TLS2_k127_5124865_68 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004443 287.0
TLS2_k127_5124865_69 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005046 280.0
TLS2_k127_5124865_7 SpoVR like protein K06415 - - 7.33e-283 873.0
TLS2_k127_5124865_70 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006125 266.0
TLS2_k127_5124865_71 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001376 273.0
TLS2_k127_5124865_72 Alpha/beta hydrolase family K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002349 261.0
TLS2_k127_5124865_73 PFAM response regulator receiver K02485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002701 245.0
TLS2_k127_5124865_74 PFAM SCP-like extracellular - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006711 249.0
TLS2_k127_5124865_75 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001548 243.0
TLS2_k127_5124865_76 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000007571 237.0
TLS2_k127_5124865_77 Ferric siderophore transporter, periplasmic energy transduction protein TonB K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000002654 235.0
TLS2_k127_5124865_79 ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000000000007202 216.0
TLS2_k127_5124865_8 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 9.981e-281 871.0
TLS2_k127_5124865_80 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000007209 216.0
TLS2_k127_5124865_81 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000000000000000000001468 210.0
TLS2_k127_5124865_82 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000001561 189.0
TLS2_k127_5124865_83 HEPN domain - - - 0.000000000000000000000000000000000000000000000001585 183.0
TLS2_k127_5124865_84 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000000000000000000000000001491 168.0
TLS2_k127_5124865_85 cell redox homeostasis K02199 - - 0.0000000000000000000000000000000000000000000005215 181.0
TLS2_k127_5124865_86 - - - - 0.0000000000000000000000000000000000000000000006317 176.0
TLS2_k127_5124865_87 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000003402 186.0
TLS2_k127_5124865_88 - - - - 0.000000000000000000000000000000000000000000005275 170.0
TLS2_k127_5124865_9 His Kinase A (phosphoacceptor) domain - - - 1.385e-242 767.0
TLS2_k127_5124865_90 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000004443 173.0
TLS2_k127_5124865_91 chromate transporter K07240 - - 0.0000000000000000000000000000000001933 145.0
TLS2_k127_5124865_92 Chromate transporter K07240 - - 0.0000000000000000000000000000000006538 138.0
TLS2_k127_5124865_93 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000001428 141.0
TLS2_k127_5124865_94 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000001651 137.0
TLS2_k127_5124865_96 signal sequence binding - - - 0.000000000000000000000000008933 115.0
TLS2_k127_5124865_98 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000002475 110.0
TLS2_k127_5124865_99 Cupin domain - - - 0.0000000000000000000009234 99.0
TLS2_k127_5140619_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 627.0
TLS2_k127_5140619_1 PFAM Na Pi-cotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 400.0
TLS2_k127_5140619_2 PFAM NMT1 THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 375.0
TLS2_k127_5140619_3 polyphosphate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 362.0
TLS2_k127_5140619_4 PFAM Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003841 284.0
TLS2_k127_5157060_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0 1170.0
TLS2_k127_5157060_1 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 571.0
TLS2_k127_5157060_10 - - - - 0.0000000000000000000000000000000004333 153.0
TLS2_k127_5157060_11 protein conserved in cyanobacteria - - - 0.0000000000000002251 84.0
TLS2_k127_5157060_2 SNF2 family N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 503.0
TLS2_k127_5157060_3 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 428.0
TLS2_k127_5157060_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 434.0
TLS2_k127_5157060_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 385.0
TLS2_k127_5157060_6 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 372.0
TLS2_k127_5157060_7 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003748 288.0
TLS2_k127_5157060_8 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004544 236.0
TLS2_k127_5157060_9 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000121 159.0
TLS2_k127_5166014_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 1.095e-283 906.0
TLS2_k127_5166014_1 acyl-CoA dehydrogenase K09456 - - 7.351e-260 815.0
TLS2_k127_5166014_10 Aminotransferase K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 415.0
TLS2_k127_5166014_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 353.0
TLS2_k127_5166014_12 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 348.0
TLS2_k127_5166014_13 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 362.0
TLS2_k127_5166014_15 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008034 282.0
TLS2_k127_5166014_16 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000000000000000000000000000000000000001183 214.0
TLS2_k127_5166014_18 multisubunit Na H antiporter MnhE subunit K05569 - - 0.00000000000000000000000000000000000000002338 160.0
TLS2_k127_5166014_19 Universal stress protein family - - - 0.00000000000000000000000000000000007403 147.0
TLS2_k127_5166014_2 Stage II sporulation protein - - - 2.92e-239 751.0
TLS2_k127_5166014_21 Na H antiporter, MnhB K05566 - - 0.00000000000000000000000000000008562 130.0
TLS2_k127_5166014_22 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000006529 122.0
TLS2_k127_5166014_23 heme binding K06194,K06401,K21472,K21473 - - 0.000000000000000000000001589 111.0
TLS2_k127_5166014_24 Na+/H+ antiporter subunit K05571 - - 0.00000000000000000000001898 111.0
TLS2_k127_5166014_25 Cold shock K03704 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006275,GO:0006355,GO:0006950,GO:0008150,GO:0008156,GO:0009266,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000005214 96.0
TLS2_k127_5166014_26 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000006234 81.0
TLS2_k127_5166014_27 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.000000000000005022 80.0
TLS2_k127_5166014_28 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000005572 65.0
TLS2_k127_5166014_3 Tetratricopeptide repeat - - - 1.129e-224 724.0
TLS2_k127_5166014_5 Domain of unknown function (DUF4040) K05559,K05565 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 627.0
TLS2_k127_5166014_6 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 598.0
TLS2_k127_5166014_7 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 547.0
TLS2_k127_5166014_8 Proton-conducting membrane transporter K05568,K12141 GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 531.0
TLS2_k127_5166014_9 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 479.0
TLS2_k127_5308304_0 Transglycosylase SLT domain K08309 - - 2.035e-282 891.0
TLS2_k127_5308304_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.636e-249 779.0
TLS2_k127_5308304_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 407.0
TLS2_k127_5308304_11 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 340.0
TLS2_k127_5308304_12 Histidine kinase K07637,K07638,K07717 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 342.0
TLS2_k127_5308304_13 sporulation resulting in formation of a cellular spore K06381 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006021 279.0
TLS2_k127_5308304_14 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000004602 220.0
TLS2_k127_5308304_15 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000004005 217.0
TLS2_k127_5308304_16 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000001328 189.0
TLS2_k127_5308304_17 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000002346 156.0
TLS2_k127_5308304_18 - - - - 0.00000000000000000000000000009575 116.0
TLS2_k127_5308304_19 glycosyl transferase group 1 - - - 0.0000000000000000000000003507 119.0
TLS2_k127_5308304_2 Domain of Unknown Function (DUF349) - - - 2.464e-246 790.0
TLS2_k127_5308304_20 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000008877 115.0
TLS2_k127_5308304_21 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000008126 100.0
TLS2_k127_5308304_22 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000004308 95.0
TLS2_k127_5308304_24 Domain of Unknown Function (DUF350) - - - 0.00000000002303 70.0
TLS2_k127_5308304_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 3.41e-200 636.0
TLS2_k127_5308304_4 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 595.0
TLS2_k127_5308304_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 526.0
TLS2_k127_5308304_6 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 445.0
TLS2_k127_5308304_7 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 399.0
TLS2_k127_5308304_8 Domain of unknown function (DUF4178) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 417.0
TLS2_k127_5308304_9 Response regulator, receiver K02488,K07719 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 400.0
TLS2_k127_5366728_0 Zinc carboxypeptidase - - - 0.0 1167.0
TLS2_k127_5366728_1 - - - - 3.268e-229 731.0
TLS2_k127_5366728_10 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 434.0
TLS2_k127_5366728_11 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 430.0
TLS2_k127_5366728_12 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 415.0
TLS2_k127_5366728_13 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 391.0
TLS2_k127_5366728_14 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 370.0
TLS2_k127_5366728_15 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 354.0
TLS2_k127_5366728_16 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 324.0
TLS2_k127_5366728_18 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 310.0
TLS2_k127_5366728_19 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005382 251.0
TLS2_k127_5366728_2 Domain of unknown function (DUF4157) - - - 9.505e-227 762.0
TLS2_k127_5366728_20 - - - - 0.000000000000000000000000000000000000000000000000001553 198.0
TLS2_k127_5366728_22 Acyl-ACP thioesterase K07107 - - 0.000000000000000000000000000000000000000000000004359 181.0
TLS2_k127_5366728_24 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000001344 136.0
TLS2_k127_5366728_25 deoxyhypusine monooxygenase activity K05386 - - 0.000000000000000000002177 101.0
TLS2_k127_5366728_26 - - - - 0.000000000000000006526 97.0
TLS2_k127_5366728_3 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 3.867e-216 679.0
TLS2_k127_5366728_4 AMP-binding enzyme C-terminal domain - - - 9.917e-215 706.0
TLS2_k127_5366728_5 GntP family permease - - - 4.724e-203 640.0
TLS2_k127_5366728_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 565.0
TLS2_k127_5366728_7 Belongs to the BCCT transporter (TC 2.A.15) family K02168 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 542.0
TLS2_k127_5366728_8 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 492.0
TLS2_k127_5366728_9 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 474.0
TLS2_k127_5367143_0 4Fe-4S dicluster domain K00184 - - 0.0 1089.0
TLS2_k127_5367143_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 5.591e-287 906.0
TLS2_k127_5367143_10 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 398.0
TLS2_k127_5367143_11 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001385 263.0
TLS2_k127_5367143_12 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001486 262.0
TLS2_k127_5367143_13 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000001807 255.0
TLS2_k127_5367143_14 PFAM Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001656 237.0
TLS2_k127_5367143_15 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000009624 233.0
TLS2_k127_5367143_16 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000004893 231.0
TLS2_k127_5367143_17 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000002213 229.0
TLS2_k127_5367143_18 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000453 201.0
TLS2_k127_5367143_19 Protein of unknown function (DUF779) K09959 - - 0.00000000000000000000000000000000000000000000000000004394 207.0
TLS2_k127_5367143_2 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K00128,K00138 - 1.2.1.3 1.982e-282 872.0
TLS2_k127_5367143_20 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000003079 198.0
TLS2_k127_5367143_21 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000001649 197.0
TLS2_k127_5367143_22 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000007609 177.0
TLS2_k127_5367143_23 Protein of unknown function (DUF4240) - - - 0.0000000000000000000000000000000000000007126 154.0
TLS2_k127_5367143_24 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000001187 152.0
TLS2_k127_5367143_25 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000003765 149.0
TLS2_k127_5367143_26 Insecticide toxin TcdB middle/N-terminal region - - - 0.0000000000000000000000000000005443 135.0
TLS2_k127_5367143_27 CpXC protein - - - 0.0000000000000000000001069 107.0
TLS2_k127_5367143_28 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000008206 101.0
TLS2_k127_5367143_3 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 2.633e-252 803.0
TLS2_k127_5367143_30 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000009288 53.0
TLS2_k127_5367143_4 Polysulphide reductase, NrfD K00185 - - 6.26e-235 736.0
TLS2_k127_5367143_5 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 625.0
TLS2_k127_5367143_6 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 514.0
TLS2_k127_5367143_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 458.0
TLS2_k127_5367143_8 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 450.0
TLS2_k127_5367143_9 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 415.0
TLS2_k127_5475408_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1165.0
TLS2_k127_5475408_1 Protein kinase domain K12132 - 2.7.11.1 7.693e-249 793.0
TLS2_k127_5475408_11 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 518.0
TLS2_k127_5475408_12 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 470.0
TLS2_k127_5475408_13 LysM domain protein K07261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 460.0
TLS2_k127_5475408_14 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 449.0
TLS2_k127_5475408_15 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 406.0
TLS2_k127_5475408_16 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 396.0
TLS2_k127_5475408_17 RAMP superfamily K09000 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 392.0
TLS2_k127_5475408_18 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 381.0
TLS2_k127_5475408_19 Hsp70 protein K04046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 394.0
TLS2_k127_5475408_2 AAA domain - - - 3.396e-239 744.0
TLS2_k127_5475408_20 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 355.0
TLS2_k127_5475408_21 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 345.0
TLS2_k127_5475408_22 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 338.0
TLS2_k127_5475408_23 to be involved in DNA repair (RAMP superfamily) K19142 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 333.0
TLS2_k127_5475408_24 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 316.0
TLS2_k127_5475408_25 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 295.0
TLS2_k127_5475408_26 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 293.0
TLS2_k127_5475408_27 Macro domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008983 286.0
TLS2_k127_5475408_28 Macro domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008784 262.0
TLS2_k127_5475408_29 Domain of unknown function (DUF4439) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002551 255.0
TLS2_k127_5475408_3 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 8.043e-210 675.0
TLS2_k127_5475408_30 Serine hydrolase K07002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009475 253.0
TLS2_k127_5475408_31 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003675 228.0
TLS2_k127_5475408_33 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000003369 209.0
TLS2_k127_5475408_34 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000004082 184.0
TLS2_k127_5475408_35 Protein of unknown function (DUF1679) - - - 0.0000000000000000000000000000000000006961 153.0
TLS2_k127_5475408_36 Domain of unknown function (DUF4433) - - - 0.0000000000000000000000000000000000007617 141.0
TLS2_k127_5475408_37 MAPEG family - - - 0.0000000000000000000000000001641 119.0
TLS2_k127_5475408_38 - - - - 0.00000000000000000000000002959 115.0
TLS2_k127_5475408_39 Domain of unknown function (DUF4433) - - - 0.0000000000000000008476 87.0
TLS2_k127_5475408_4 N-6 DNA Methylase - - - 4.224e-203 646.0
TLS2_k127_5475408_40 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000381 98.0
TLS2_k127_5475408_41 PFAM Phosphopantetheine attachment site - - - 0.000000000000009874 79.0
TLS2_k127_5475408_42 - - - - 0.000000000001839 74.0
TLS2_k127_5475408_43 Selenium-binding protein K17285 - - 0.000000000006371 69.0
TLS2_k127_5475408_44 Domain of unknown function (DUF4440) - - - 0.00000000007909 69.0
TLS2_k127_5475408_45 Domain of unknown function (DUF4442) - - - 0.0000000002053 68.0
TLS2_k127_5475408_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 562.0
TLS2_k127_5475408_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K20427 - 2.7.7.27,2.7.7.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 546.0
TLS2_k127_5475408_7 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 539.0
TLS2_k127_5475408_8 Pfam:HxxPF_rpt - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 533.0
TLS2_k127_5475408_9 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 523.0
TLS2_k127_5624058_0 Tetratricopeptide repeat - - - 0.0 1322.0
TLS2_k127_5624058_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1088.0
TLS2_k127_5624058_11 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 526.0
TLS2_k127_5624058_12 PFAM Glutamate-cysteine ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009351 531.0
TLS2_k127_5624058_13 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 520.0
TLS2_k127_5624058_14 (ABC) transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 516.0
TLS2_k127_5624058_15 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 495.0
TLS2_k127_5624058_16 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 475.0
TLS2_k127_5624058_17 PEGA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009031 486.0
TLS2_k127_5624058_18 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 456.0
TLS2_k127_5624058_19 Bacterial regulatory protein, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 463.0
TLS2_k127_5624058_2 Peptidase family M50 K11749 - - 1.246e-271 844.0
TLS2_k127_5624058_20 Sugar (and other) transporter K08178 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 474.0
TLS2_k127_5624058_21 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 378.0
TLS2_k127_5624058_22 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 357.0
TLS2_k127_5624058_23 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 364.0
TLS2_k127_5624058_24 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 370.0
TLS2_k127_5624058_25 Adventurous gliding motility - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 338.0
TLS2_k127_5624058_26 belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 338.0
TLS2_k127_5624058_27 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 355.0
TLS2_k127_5624058_28 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 307.0
TLS2_k127_5624058_29 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 326.0
TLS2_k127_5624058_3 Endonuclease/Exonuclease/phosphatase family K07004 - - 3.207e-256 822.0
TLS2_k127_5624058_30 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 289.0
TLS2_k127_5624058_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002564 284.0
TLS2_k127_5624058_33 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000001308 271.0
TLS2_k127_5624058_34 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002676 245.0
TLS2_k127_5624058_36 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000000001386 231.0
TLS2_k127_5624058_37 - - - - 0.000000000000000000000000000000000000000000000000000000000003056 227.0
TLS2_k127_5624058_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 2.1e-241 750.0
TLS2_k127_5624058_40 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000001921 199.0
TLS2_k127_5624058_41 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000009655 185.0
TLS2_k127_5624058_42 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000007016 188.0
TLS2_k127_5624058_43 radical SAM K06871 - - 0.00000000000000000000000000000000000000001126 173.0
TLS2_k127_5624058_44 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000006177 169.0
TLS2_k127_5624058_45 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000005874 162.0
TLS2_k127_5624058_46 Hemimethylated DNA-binding protein YccV like K11940 - - 0.00000000000000000000000000000001163 144.0
TLS2_k127_5624058_47 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000003529 133.0
TLS2_k127_5624058_48 Transmembrane secretion effector - - - 0.0000000000000000000000000000003965 137.0
TLS2_k127_5624058_49 Urate oxidase N-terminal - - - 0.00000000001378 71.0
TLS2_k127_5624058_5 deoxyhypusine monooxygenase activity - - - 2.21e-223 709.0
TLS2_k127_5624058_50 - - - - 0.00000000002721 71.0
TLS2_k127_5624058_53 - - - - 0.000006934 53.0
TLS2_k127_5624058_54 peptide catabolic process - - - 0.0006409 54.0
TLS2_k127_5624058_6 RimK-like ATPgrasp N-terminal domain - - - 7.201e-194 616.0
TLS2_k127_5624058_7 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 578.0
TLS2_k127_5624058_8 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 579.0
TLS2_k127_5624058_9 Amidohydrolase family K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 545.0
TLS2_k127_5650381_0 Belongs to the heat shock protein 70 family - - - 0.0 1377.0
TLS2_k127_5650381_1 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1229.0
TLS2_k127_5650381_10 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 522.0
TLS2_k127_5650381_11 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 496.0
TLS2_k127_5650381_12 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 486.0
TLS2_k127_5650381_13 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 466.0
TLS2_k127_5650381_14 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 426.0
TLS2_k127_5650381_16 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 402.0
TLS2_k127_5650381_17 DNA-binding regulatory protein K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 389.0
TLS2_k127_5650381_18 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 375.0
TLS2_k127_5650381_19 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 362.0
TLS2_k127_5650381_2 MreB/Mbl protein - - - 3.696e-288 897.0
TLS2_k127_5650381_20 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 364.0
TLS2_k127_5650381_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 326.0
TLS2_k127_5650381_22 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 317.0
TLS2_k127_5650381_23 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 309.0
TLS2_k127_5650381_24 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 311.0
TLS2_k127_5650381_25 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 308.0
TLS2_k127_5650381_26 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 305.0
TLS2_k127_5650381_27 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000015 302.0
TLS2_k127_5650381_28 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 291.0
TLS2_k127_5650381_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 290.0
TLS2_k127_5650381_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 5.08e-237 756.0
TLS2_k127_5650381_30 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003423 299.0
TLS2_k127_5650381_31 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002303 273.0
TLS2_k127_5650381_32 Domain of unknown function (DUF2760) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002054 258.0
TLS2_k127_5650381_33 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000006146 242.0
TLS2_k127_5650381_34 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000006109 233.0
TLS2_k127_5650381_35 - - - - 0.00000000000000000000000000000000000000000000000000000000000000008424 235.0
TLS2_k127_5650381_36 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000002699 239.0
TLS2_k127_5650381_37 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000000000000001702 210.0
TLS2_k127_5650381_39 YceI-like domain - - - 0.000000000000000000000000000000000000000000000001942 188.0
TLS2_k127_5650381_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.565e-215 674.0
TLS2_k127_5650381_40 Belongs to the bacterial histone-like protein family K05788 - - 0.00000000000000000000000000000000000000000000001869 178.0
TLS2_k127_5650381_41 CBS domain K04767,K07168,K07182 - - 0.00000000000000000000000000000000004817 138.0
TLS2_k127_5650381_42 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000001053 142.0
TLS2_k127_5650381_44 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000000000000000000000000009714 135.0
TLS2_k127_5650381_45 - - - - 0.000000000000000000000000000001353 132.0
TLS2_k127_5650381_48 Bacterial regulatory proteins, tetR family - - - 0.000000000000000003512 94.0
TLS2_k127_5650381_49 neuron death in response to oxidative stress K01173 - - 0.00000000001156 74.0
TLS2_k127_5650381_5 Aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 6.675e-201 639.0
TLS2_k127_5650381_7 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.936e-194 634.0
TLS2_k127_5650381_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 602.0
TLS2_k127_5650381_9 Belongs to the ClpX chaperone family K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 589.0
TLS2_k127_5652180_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1169.0
TLS2_k127_5652180_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 2.896e-319 1000.0
TLS2_k127_5652180_10 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 506.0
TLS2_k127_5652180_11 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 493.0
TLS2_k127_5652180_12 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 460.0
TLS2_k127_5652180_13 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 441.0
TLS2_k127_5652180_14 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 396.0
TLS2_k127_5652180_15 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 293.0
TLS2_k127_5652180_16 Fumarate reductase, iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000047 280.0
TLS2_k127_5652180_17 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001444 278.0
TLS2_k127_5652180_18 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004964 271.0
TLS2_k127_5652180_19 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
TLS2_k127_5652180_2 Protein of unknown function (DUF1573) - - - 1.141e-302 951.0
TLS2_k127_5652180_20 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001143 267.0
TLS2_k127_5652180_21 fumarate reductase) cytochrome b subunit K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002284 252.0
TLS2_k127_5652180_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004151 228.0
TLS2_k127_5652180_24 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000007915 198.0
TLS2_k127_5652180_25 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000002552 211.0
TLS2_k127_5652180_27 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000000000000000741 147.0
TLS2_k127_5652180_28 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000008194 158.0
TLS2_k127_5652180_29 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000000006933 147.0
TLS2_k127_5652180_3 Lysin motif K08307 - - 3.313e-287 899.0
TLS2_k127_5652180_31 protein secretion K03116 - - 0.00000000000000000000007063 100.0
TLS2_k127_5652180_4 Belongs to the glycosyl hydrolase 57 family - - - 9.521e-281 884.0
TLS2_k127_5652180_5 serine threonine protein kinase K12132 - 2.7.11.1 5.953e-275 864.0
TLS2_k127_5652180_6 Domain of unknown function (DUF4157) - - - 2.796e-253 805.0
TLS2_k127_5652180_7 AbgT putative transporter family - - - 2.279e-216 683.0
TLS2_k127_5652180_9 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 585.0
TLS2_k127_565396_0 Tetratricopeptide repeats - - - 0.0 3197.0
TLS2_k127_565396_1 WD domain- G-beta repeat PBS lyase HEAT-like K03497 - - 0.0 2127.0
TLS2_k127_565396_10 PA14 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006436 438.0
TLS2_k127_565396_11 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 426.0
TLS2_k127_565396_12 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 368.0
TLS2_k127_565396_14 Cytokinin dehydrogenase 1, FAD and cytokinin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 345.0
TLS2_k127_565396_15 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 331.0
TLS2_k127_565396_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 303.0
TLS2_k127_565396_17 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005581 280.0
TLS2_k127_565396_18 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002456 271.0
TLS2_k127_565396_19 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 0.000000000000000000000000000000000000000000000000000000000002444 233.0
TLS2_k127_565396_2 Ompa motb domain protein - - - 0.0 1504.0
TLS2_k127_565396_22 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000004595 203.0
TLS2_k127_565396_23 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000002477 154.0
TLS2_k127_565396_24 - - - - 0.0000000000000000000000000000000003435 142.0
TLS2_k127_565396_25 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000001416 142.0
TLS2_k127_565396_26 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000008703 133.0
TLS2_k127_565396_27 bacterial-type flagellum organization K02411 - - 0.000000000000000000005996 99.0
TLS2_k127_565396_3 deoxyhypusine monooxygenase activity - - - 0.0 1222.0
TLS2_k127_565396_30 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000005239 72.0
TLS2_k127_565396_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA - - - 0.0 1140.0
TLS2_k127_565396_5 Zinc finger, swim domain protein - - - 3.239e-269 863.0
TLS2_k127_565396_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 1.484e-264 865.0
TLS2_k127_565396_7 RNA-directed DNA polymerase K00986 - 2.7.7.49 1.037e-209 662.0
TLS2_k127_565396_8 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 574.0
TLS2_k127_565396_9 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 467.0
TLS2_k127_5658534_0 PFAM TonB-dependent receptor plug K02014,K16089 - - 1.21e-304 998.0
TLS2_k127_5658534_1 PFAM TonB-dependent receptor plug K02014,K16089 - - 7.83e-300 989.0
TLS2_k127_5658534_2 glutaminyl-tRNA K01886 - 6.1.1.18 4.765e-297 923.0
TLS2_k127_5658534_3 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000000000000001192 151.0
TLS2_k127_5658534_5 Salmonella virulence plasmid 28.1kDa A protein - - - 0.0000682 47.0
TLS2_k127_5667050_0 Protein kinase domain - - - 0.0 1294.0
TLS2_k127_5667050_1 serine threonine protein kinase K12132 - 2.7.11.1 4.612e-302 966.0
TLS2_k127_5667050_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 381.0
TLS2_k127_5667050_11 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 376.0
TLS2_k127_5667050_12 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 360.0
TLS2_k127_5667050_13 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 357.0
TLS2_k127_5667050_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 350.0
TLS2_k127_5667050_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 326.0
TLS2_k127_5667050_16 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 324.0
TLS2_k127_5667050_19 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000004253 176.0
TLS2_k127_5667050_2 Aamy_C K01176 - 3.2.1.1 1.305e-280 874.0
TLS2_k127_5667050_20 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000001808 154.0
TLS2_k127_5667050_21 - - - - 0.000000000000000000000000409 108.0
TLS2_k127_5667050_22 Membrane - - - 0.00000000000000000000005951 113.0
TLS2_k127_5667050_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 5.471e-214 692.0
TLS2_k127_5667050_4 protein kinase activity - - - 4.119e-207 679.0
TLS2_k127_5667050_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 621.0
TLS2_k127_5667050_6 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 511.0
TLS2_k127_5667050_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 495.0
TLS2_k127_5667050_8 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 422.0
TLS2_k127_5667050_9 sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 419.0
TLS2_k127_5670079_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1259.0
TLS2_k127_5670079_1 PFAM carboxyl transferase K01615 - 4.1.1.70 0.0 1009.0
TLS2_k127_5670079_10 HEAT repeats - - - 2.346e-221 719.0
TLS2_k127_5670079_100 His Kinase A (phosphoacceptor) domain - - - 0.0000001424 58.0
TLS2_k127_5670079_101 S23 ribosomal protein - - - 0.000005952 54.0
TLS2_k127_5670079_102 His Kinase A (phosphoacceptor) domain - - - 0.00000918 54.0
TLS2_k127_5670079_104 23S rRNA-intervening sequence protein - - - 0.0002177 51.0
TLS2_k127_5670079_11 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.515e-215 676.0
TLS2_k127_5670079_12 Type II secretion system (T2SS), protein E, N-terminal domain - - - 3.686e-215 696.0
TLS2_k127_5670079_13 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 602.0
TLS2_k127_5670079_14 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 601.0
TLS2_k127_5670079_15 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 605.0
TLS2_k127_5670079_16 CheY-like receiver AAA-type ATPase and DNA-binding domains K11384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 599.0
TLS2_k127_5670079_17 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 599.0
TLS2_k127_5670079_18 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 600.0
TLS2_k127_5670079_19 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 544.0
TLS2_k127_5670079_2 ABC1 family - - - 6.657e-274 858.0
TLS2_k127_5670079_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 531.0
TLS2_k127_5670079_21 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 502.0
TLS2_k127_5670079_22 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 496.0
TLS2_k127_5670079_23 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 471.0
TLS2_k127_5670079_24 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 430.0
TLS2_k127_5670079_25 alpha/beta hydrolase fold K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 433.0
TLS2_k127_5670079_26 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 431.0
TLS2_k127_5670079_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 435.0
TLS2_k127_5670079_28 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 426.0
TLS2_k127_5670079_29 ggdef domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 412.0
TLS2_k127_5670079_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 1.161e-258 820.0
TLS2_k127_5670079_30 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 396.0
TLS2_k127_5670079_31 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 389.0
TLS2_k127_5670079_32 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 391.0
TLS2_k127_5670079_33 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 384.0
TLS2_k127_5670079_34 Responsible for synthesis of pseudouridine from uracil - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 376.0
TLS2_k127_5670079_35 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 361.0
TLS2_k127_5670079_37 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 361.0
TLS2_k127_5670079_38 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 375.0
TLS2_k127_5670079_39 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575,K02661 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 374.0
TLS2_k127_5670079_4 Histidine kinase K15011 - 2.7.13.3 6.64e-243 756.0
TLS2_k127_5670079_41 UMP catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 352.0
TLS2_k127_5670079_42 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 338.0
TLS2_k127_5670079_43 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 321.0
TLS2_k127_5670079_44 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 330.0
TLS2_k127_5670079_46 COG0846 NAD-dependent protein deacetylases, SIR2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 306.0
TLS2_k127_5670079_47 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 315.0
TLS2_k127_5670079_48 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 311.0
TLS2_k127_5670079_5 - - - - 2.956e-234 729.0
TLS2_k127_5670079_50 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 311.0
TLS2_k127_5670079_51 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 316.0
TLS2_k127_5670079_52 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 302.0
TLS2_k127_5670079_53 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002622 287.0
TLS2_k127_5670079_55 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000001933 271.0
TLS2_k127_5670079_56 ATPase involved in DNA repair K03529,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000003238 280.0
TLS2_k127_5670079_57 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006553 251.0
TLS2_k127_5670079_58 HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000001823 245.0
TLS2_k127_5670079_59 regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000002325 236.0
TLS2_k127_5670079_6 Insulinase (Peptidase family M16) K07263 - - 7.346e-234 747.0
TLS2_k127_5670079_60 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000524 239.0
TLS2_k127_5670079_61 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002562 241.0
TLS2_k127_5670079_62 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000231 224.0
TLS2_k127_5670079_63 - - - - 0.0000000000000000000000000000000000000000000000000000000000002542 219.0
TLS2_k127_5670079_64 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000005708 206.0
TLS2_k127_5670079_65 ligase activity, forming carbon-carbon bonds K00627,K00645,K01572,K02160 - 2.3.1.12,2.3.1.39,4.1.1.3 0.000000000000000000000000000000000000000000000000000000005416 207.0
TLS2_k127_5670079_66 - - - - 0.00000000000000000000000000000000000000000000000000000002227 210.0
TLS2_k127_5670079_67 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000000002785 198.0
TLS2_k127_5670079_68 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000003484 195.0
TLS2_k127_5670079_69 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000001872 198.0
TLS2_k127_5670079_7 serine threonine protein kinase K12132 - 2.7.11.1 4.121e-228 735.0
TLS2_k127_5670079_70 Acetyltransferase (GNAT) domain K03817 - - 0.00000000000000000000000000000000000000000000000000008067 194.0
TLS2_k127_5670079_71 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000002542 205.0
TLS2_k127_5670079_72 dihydrofolate reductase activity K00287 GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0031406,GO:0033218,GO:0034641,GO:0036094,GO:0042221,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0071704,GO:0072341,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.3 0.0000000000000000000000000000000000000000000000000006679 201.0
TLS2_k127_5670079_73 deoxyhypusine monooxygenase activity K05385 - - 0.000000000000000000000000000000000000000000000000005267 192.0
TLS2_k127_5670079_74 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000005876 177.0
TLS2_k127_5670079_75 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000009212 172.0
TLS2_k127_5670079_76 Domain of unknown function (DUF4331) - - - 0.0000000000000000000000000000000000000000003988 168.0
TLS2_k127_5670079_77 regulation of translation K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000003768 163.0
TLS2_k127_5670079_79 RNA-binding - - - 0.000000000000000000000000000000000007848 145.0
TLS2_k127_5670079_8 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 3.227e-224 722.0
TLS2_k127_5670079_80 chemotaxis K03408 - - 0.0000000000000000000000000000000000137 147.0
TLS2_k127_5670079_81 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000005692 151.0
TLS2_k127_5670079_82 Membrane protein involved in the export of O-antigen and teichoic acid K03328,K16695 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000005699 149.0
TLS2_k127_5670079_83 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000000003134 136.0
TLS2_k127_5670079_86 ThiS family - - - 0.000000000000000000000000000003179 125.0
TLS2_k127_5670079_87 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.000000000000000000000000000006423 131.0
TLS2_k127_5670079_89 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000001502 114.0
TLS2_k127_5670079_9 Histidine kinase K03407,K13490 - 2.7.13.3 1.195e-223 716.0
TLS2_k127_5670079_90 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000003195 120.0
TLS2_k127_5670079_91 - - - - 0.0000000000000000000000001369 107.0
TLS2_k127_5670079_92 Putative mono-oxygenase ydhR - - - 0.00000000000000000005522 96.0
TLS2_k127_5670079_93 Vitamin K-dependent gamma-carboxylase - - - 0.000000000000000007344 96.0
TLS2_k127_5670079_96 His Kinase A (phosphoacceptor) domain - - - 0.000000000002415 73.0
TLS2_k127_5670079_97 Domain of unknown function (DUF1998) K06877 - - 0.000000000002672 82.0
TLS2_k127_5670079_98 - - - - 0.000000000007121 78.0
TLS2_k127_5670079_99 Domain of unknown function (DUF4331) - - - 0.00000000005006 72.0
TLS2_k127_5697395_0 Belongs to the UPF0753 family K09822 - - 6.901e-294 938.0
TLS2_k127_5697395_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 424.0
TLS2_k127_5697395_2 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 321.0
TLS2_k127_5697395_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001174 274.0
TLS2_k127_5697395_4 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000173 276.0
TLS2_k127_5697395_5 Response regulator receiver K02485 - - 0.000000000000000000000000000000000000000000000000001786 197.0
TLS2_k127_5697395_6 protein conserved in cyanobacteria - - - 0.000000002647 64.0
TLS2_k127_5728446_0 Family membership - - - 0.0 1560.0
TLS2_k127_5728446_1 TIGRFAM RHS repeat-associated core domain - - - 0.0 1096.0
TLS2_k127_5728446_10 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 6.164e-227 711.0
TLS2_k127_5728446_11 PFAM Archaeal ATPase - - - 5.021e-213 673.0
TLS2_k127_5728446_12 Bacterial protein of unknown function (DUF885) - - - 2.779e-210 674.0
TLS2_k127_5728446_13 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 593.0
TLS2_k127_5728446_14 TOBE domain K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 574.0
TLS2_k127_5728446_15 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 493.0
TLS2_k127_5728446_16 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 493.0
TLS2_k127_5728446_17 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 470.0
TLS2_k127_5728446_18 Aminotransferase class-III K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 474.0
TLS2_k127_5728446_19 Cell division protein FtsI penicillin-binding protein 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 464.0
TLS2_k127_5728446_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1070.0
TLS2_k127_5728446_20 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 454.0
TLS2_k127_5728446_21 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 459.0
TLS2_k127_5728446_22 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 433.0
TLS2_k127_5728446_23 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 424.0
TLS2_k127_5728446_24 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 410.0
TLS2_k127_5728446_25 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 417.0
TLS2_k127_5728446_26 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 389.0
TLS2_k127_5728446_27 Belongs to the ABC transporter superfamily K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 381.0
TLS2_k127_5728446_28 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 353.0
TLS2_k127_5728446_29 protein trimerization K05807,K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 334.0
TLS2_k127_5728446_3 RecQ zinc-binding K03654 - 3.6.4.12 0.0 1053.0
TLS2_k127_5728446_30 Bacterial extracellular solute-binding protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 354.0
TLS2_k127_5728446_31 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007594 334.0
TLS2_k127_5728446_32 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 317.0
TLS2_k127_5728446_33 cell adhesion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007665 288.0
TLS2_k127_5728446_34 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005541 273.0
TLS2_k127_5728446_35 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003462 263.0
TLS2_k127_5728446_36 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005008 276.0
TLS2_k127_5728446_37 Binding-protein-dependent transport system inner membrane component K02053,K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000002587 251.0
TLS2_k127_5728446_38 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000001148 229.0
TLS2_k127_5728446_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.779e-275 855.0
TLS2_k127_5728446_43 Domain of unknown function (DUF4360) - - - 0.0000000000000000000000000000000000000000000000002478 183.0
TLS2_k127_5728446_44 Domain of unknown function (DUF4360) - - - 0.00000000000000000000000000000000000000000000009812 179.0
TLS2_k127_5728446_45 Domain of unknown function (DUF4360) - - - 0.000000000000000000000000000000000000000000001567 173.0
TLS2_k127_5728446_46 Domain of unknown function (DUF4360) - - - 0.00000000000000000000000000000000000000000002546 169.0
TLS2_k127_5728446_47 Domain of unknown function (DUF4360) - - - 0.0000000000000000000000000000000000000000001006 167.0
TLS2_k127_5728446_5 Na H antiporter - - - 1.636e-258 814.0
TLS2_k127_5728446_50 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000000000000000338 151.0
TLS2_k127_5728446_51 Domain of unknown function (DUF4360) - - - 0.00000000000000000000000000000001308 135.0
TLS2_k127_5728446_52 - - - - 0.0000000000000000000000000000165 136.0
TLS2_k127_5728446_53 - - - - 0.000000000000000000000000002492 120.0
TLS2_k127_5728446_54 - - - - 0.000000003489 70.0
TLS2_k127_5728446_55 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00001349 52.0
TLS2_k127_5728446_56 Domain of unknown function (DUF4360) - - - 0.0002032 51.0
TLS2_k127_5728446_6 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.777e-251 816.0
TLS2_k127_5728446_7 AMP-binding enzyme C-terminal domain K22319 - 6.1.3.1 3.91e-241 754.0
TLS2_k127_5728446_8 Aldehyde dehydrogenase family K00130 - 1.2.1.8 1.028e-235 742.0
TLS2_k127_5728446_9 Phosphate acyltransferases K00631 - 2.3.1.15 7.304e-231 725.0
TLS2_k127_5769789_0 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 387.0
TLS2_k127_5769789_1 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 355.0
TLS2_k127_5769789_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 306.0
TLS2_k127_5769789_3 IPT/TIG domain - - - 0.0000000000000000000000000000000000000001644 164.0
TLS2_k127_5769789_4 Hemerythrin - - - 0.0006382 49.0
TLS2_k127_5780122_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 0.0 1122.0
TLS2_k127_5780122_1 SMART serine threonine protein kinase - - - 9.043e-313 1005.0
TLS2_k127_5780122_10 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 458.0
TLS2_k127_5780122_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 443.0
TLS2_k127_5780122_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 449.0
TLS2_k127_5780122_13 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 422.0
TLS2_k127_5780122_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 428.0
TLS2_k127_5780122_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 399.0
TLS2_k127_5780122_16 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 397.0
TLS2_k127_5780122_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 367.0
TLS2_k127_5780122_18 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 364.0
TLS2_k127_5780122_19 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 312.0
TLS2_k127_5780122_2 chaperone-mediated protein folding - - - 2.294e-276 872.0
TLS2_k127_5780122_20 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 298.0
TLS2_k127_5780122_21 PFAM DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 307.0
TLS2_k127_5780122_22 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 309.0
TLS2_k127_5780122_23 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 304.0
TLS2_k127_5780122_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006 287.0
TLS2_k127_5780122_25 3D domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001202 280.0
TLS2_k127_5780122_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001031 243.0
TLS2_k127_5780122_27 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000001279 239.0
TLS2_k127_5780122_28 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003371 228.0
TLS2_k127_5780122_29 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000000000000000000008402 206.0
TLS2_k127_5780122_3 Domain of unknown function (DUF362) - - - 5.82e-222 691.0
TLS2_k127_5780122_30 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000000001301 196.0
TLS2_k127_5780122_32 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000776 188.0
TLS2_k127_5780122_33 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000001114 181.0
TLS2_k127_5780122_34 Belongs to the sigma-70 factor family K02405 - - 0.0000000000000000000000000000000001344 142.0
TLS2_k127_5780122_35 - - - - 0.00000000000000000000000000000002087 132.0
TLS2_k127_5780122_36 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000896 123.0
TLS2_k127_5780122_38 DUF167 K09131 - - 0.0000000000000000000001355 110.0
TLS2_k127_5780122_39 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000002406 106.0
TLS2_k127_5780122_4 PFAM Archaeal ATPase - - - 5.477e-220 693.0
TLS2_k127_5780122_40 Psort location Periplasmic, score K09807 - - 0.0000000000000000003394 96.0
TLS2_k127_5780122_41 Peptidase family S58 K01266 - 3.4.11.19 0.00005287 50.0
TLS2_k127_5780122_42 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0001212 54.0
TLS2_k127_5780122_5 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 1.63e-213 669.0
TLS2_k127_5780122_6 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 4.488e-202 636.0
TLS2_k127_5780122_7 Acyl-CoA dehydrogenase, N-terminal domain - - - 3.959e-197 620.0
TLS2_k127_5780122_8 Histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 534.0
TLS2_k127_5780122_9 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 492.0
TLS2_k127_5789782_0 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 8.94e-264 829.0
TLS2_k127_5789782_1 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 576.0
TLS2_k127_5789782_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 459.0
TLS2_k127_5789782_3 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 467.0
TLS2_k127_5789782_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 349.0
TLS2_k127_5789782_5 Phosphoribulokinase / Uridine kinase family K00855,K00876 - 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 316.0
TLS2_k127_5789782_6 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000003113 152.0
TLS2_k127_5789782_7 COG3209 Rhs family protein - - - 0.0000000000000000000866 97.0
TLS2_k127_5789782_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.000000000000000001753 94.0
TLS2_k127_5789782_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000007049 79.0
TLS2_k127_5803589_0 repeat protein - - - 0.0 2154.0
TLS2_k127_5803589_1 4Fe-4S dicluster domain K00184 - - 0.0 1339.0
TLS2_k127_5803589_10 serine threonine protein kinase K08884,K12132 - 2.7.11.1 9.048e-216 698.0
TLS2_k127_5803589_11 Kelch motif - - - 1.768e-196 648.0
TLS2_k127_5803589_12 5' nucleotidase family - - - 5.413e-195 618.0
TLS2_k127_5803589_13 PA domain K01342,K14645 - 3.4.21.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 619.0
TLS2_k127_5803589_14 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 601.0
TLS2_k127_5803589_15 PA domain K01342,K14645 - 3.4.21.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 593.0
TLS2_k127_5803589_16 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 565.0
TLS2_k127_5803589_17 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 534.0
TLS2_k127_5803589_18 Cytokinin dehydrogenase 1, FAD and cytokinin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 499.0
TLS2_k127_5803589_19 Malic enzyme, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 437.0
TLS2_k127_5803589_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1280.0
TLS2_k127_5803589_20 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 439.0
TLS2_k127_5803589_21 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 412.0
TLS2_k127_5803589_22 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 417.0
TLS2_k127_5803589_23 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 398.0
TLS2_k127_5803589_24 Protein of unknown function (DUF533) K06596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 394.0
TLS2_k127_5803589_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 379.0
TLS2_k127_5803589_26 response regulator K02282,K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 355.0
TLS2_k127_5803589_28 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 345.0
TLS2_k127_5803589_29 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 342.0
TLS2_k127_5803589_3 Belongs to the heat shock protein 70 family K04043 - - 0.0 1188.0
TLS2_k127_5803589_30 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 288.0
TLS2_k127_5803589_32 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008287 270.0
TLS2_k127_5803589_33 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002152 304.0
TLS2_k127_5803589_34 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006716 262.0
TLS2_k127_5803589_35 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006105 281.0
TLS2_k127_5803589_36 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003078 261.0
TLS2_k127_5803589_37 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004873 263.0
TLS2_k127_5803589_38 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000001439 231.0
TLS2_k127_5803589_4 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 0.0 1102.0
TLS2_k127_5803589_40 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000001177 209.0
TLS2_k127_5803589_41 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000001924 214.0
TLS2_k127_5803589_42 protein with SCP PR1 domains - - - 0.00000000000000000000000000000000000000000000000000008172 192.0
TLS2_k127_5803589_44 TIGRFAM cysteine-rich repeat protein - - - 0.0000000000000000000000000000000000000000000000000007306 198.0
TLS2_k127_5803589_45 - - - - 0.000000000000000000000000000000000000000000003134 182.0
TLS2_k127_5803589_46 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000000000000000000000000002478 147.0
TLS2_k127_5803589_47 lysozyme - - - 0.000000000000000000000000000000000007598 150.0
TLS2_k127_5803589_48 - - - - 0.000000000000000000000000000007943 138.0
TLS2_k127_5803589_49 protein kinase activity - - - 0.0000000000000000000000001366 116.0
TLS2_k127_5803589_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.512e-303 960.0
TLS2_k127_5803589_51 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000003608 94.0
TLS2_k127_5803589_52 PAS fold - - - 0.00000000000000006444 85.0
TLS2_k127_5803589_6 serine threonine protein kinase K12132 - 2.7.11.1 1.826e-287 911.0
TLS2_k127_5803589_7 Polysulphide reductase, NrfD K00185 - - 1.065e-266 824.0
TLS2_k127_5803589_8 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 7.314e-229 720.0
TLS2_k127_5803589_9 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 6.171e-216 676.0
TLS2_k127_5805983_0 Bacterial capsule synthesis protein PGA_cap - - - 1.606e-214 694.0
TLS2_k127_5805983_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 8.163e-212 690.0
TLS2_k127_5805983_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 581.0
TLS2_k127_5805983_3 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 573.0
TLS2_k127_5805983_4 Flagellar Motor Protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 464.0
TLS2_k127_5805983_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001325 289.0
TLS2_k127_5818413_0 Periplasmic protein TonB links inner and outer membranes - - - 0.0 1220.0
TLS2_k127_5818413_1 DEAD DEAH box helicase - - - 0.0 1123.0
TLS2_k127_5818413_10 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 362.0
TLS2_k127_5818413_11 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 328.0
TLS2_k127_5818413_12 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 313.0
TLS2_k127_5818413_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 326.0
TLS2_k127_5818413_14 photoreceptor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001251 307.0
TLS2_k127_5818413_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002961 278.0
TLS2_k127_5818413_16 PFAM DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002163 274.0
TLS2_k127_5818413_17 thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000005459 228.0
TLS2_k127_5818413_19 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000007843 229.0
TLS2_k127_5818413_2 Vault protein inter-alpha-trypsin domain - - - 0.0 1097.0
TLS2_k127_5818413_20 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891,K15546 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000002111 220.0
TLS2_k127_5818413_21 - - - - 0.0000000000000000000000000000000000000000000000000000352 191.0
TLS2_k127_5818413_22 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000003789 178.0
TLS2_k127_5818413_24 Adenylylsulfate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000002773 170.0
TLS2_k127_5818413_25 - - - - 0.000000000000000000000000000000000004679 146.0
TLS2_k127_5818413_26 Band 7 protein K07192 - - 0.000000000000000000000000000000003748 146.0
TLS2_k127_5818413_27 Belongs to the ompA family - - - 0.0000000000000000000000008546 109.0
TLS2_k127_5818413_28 Protein of unknown function (DUF3293) - - - 0.000000000000000000238 94.0
TLS2_k127_5818413_3 Band 7 protein - - - 0.0 1094.0
TLS2_k127_5818413_30 Endonuclease Exonuclease Phosphatase - - - 0.00000000002698 76.0
TLS2_k127_5818413_32 Band 7 protein - - - 0.00000006417 56.0
TLS2_k127_5818413_4 benzoyl-CoA oxygenase K15512 - 1.14.13.208 6.085e-275 877.0
TLS2_k127_5818413_5 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 2.132e-271 844.0
TLS2_k127_5818413_6 PFAM AAA ATPase central domain protein - - - 1.274e-234 766.0
TLS2_k127_5818413_7 Cation transport protein K03498 - - 5.64e-201 660.0
TLS2_k127_5818413_8 alkyl hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 444.0
TLS2_k127_5818413_9 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 436.0
TLS2_k127_5875450_0 SMART serine threonine protein kinase - - - 0.0 1108.0
TLS2_k127_5875450_1 PFAM Archaeal ATPase - - - 1.568e-215 681.0
TLS2_k127_5875450_10 TIGRFAM cysteine-rich repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001543 233.0
TLS2_k127_5875450_11 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000006554 114.0
TLS2_k127_5875450_12 zinc ion binding K06204 - - 0.00000000000000000000008478 102.0
TLS2_k127_5875450_13 amine dehydrogenase activity - - - 0.00003934 46.0
TLS2_k127_5875450_2 TIGRFAM cysteine-rich repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 582.0
TLS2_k127_5875450_3 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 429.0
TLS2_k127_5875450_4 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 419.0
TLS2_k127_5875450_5 Sterol carrier protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 412.0
TLS2_k127_5875450_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 413.0
TLS2_k127_5875450_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 320.0
TLS2_k127_5875450_8 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 308.0
TLS2_k127_5875450_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 307.0
TLS2_k127_5933117_0 ERAP1-like C-terminal domain K01263 - 3.4.11.14 5.992e-268 852.0
TLS2_k127_5933117_1 Biotin carboxylase C-terminal domain K01968,K13777 - 6.4.1.4,6.4.1.5 3.864e-266 839.0
TLS2_k127_5933117_10 Serine Threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 487.0
TLS2_k127_5933117_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 437.0
TLS2_k127_5933117_12 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 411.0
TLS2_k127_5933117_13 acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 392.0
TLS2_k127_5933117_14 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 332.0
TLS2_k127_5933117_15 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 321.0
TLS2_k127_5933117_16 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 323.0
TLS2_k127_5933117_17 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 319.0
TLS2_k127_5933117_18 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005304 282.0
TLS2_k127_5933117_19 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006979 256.0
TLS2_k127_5933117_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 5.649e-245 762.0
TLS2_k127_5933117_20 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000408 245.0
TLS2_k127_5933117_21 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000008475 235.0
TLS2_k127_5933117_22 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000006777 236.0
TLS2_k127_5933117_23 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000099 221.0
TLS2_k127_5933117_24 - - - - 0.000000000000000000000000000000000000000000000000000003232 199.0
TLS2_k127_5933117_25 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000000000002446 188.0
TLS2_k127_5933117_26 arginine transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000004937 188.0
TLS2_k127_5933117_27 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000102 149.0
TLS2_k127_5933117_29 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000511 142.0
TLS2_k127_5933117_3 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 5.466e-239 774.0
TLS2_k127_5933117_30 M6 family metalloprotease domain protein - - - 0.00000000000000000000000002384 128.0
TLS2_k127_5933117_31 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000002291 114.0
TLS2_k127_5933117_33 Cytochrome c - - - 0.0000000000000001566 95.0
TLS2_k127_5933117_34 tetraacyldisaccharide 4'-kinase activity K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.0000000000005132 73.0
TLS2_k127_5933117_35 Extracellular nuclease K07004 - - 0.0000000000008845 83.0
TLS2_k127_5933117_36 Belongs to the ompA family K03286 - - 0.0000000000588 68.0
TLS2_k127_5933117_37 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000006397 68.0
TLS2_k127_5933117_38 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000004661 55.0
TLS2_k127_5933117_4 PFAM MscS Mechanosensitive ion channel K16052 - - 3.769e-230 734.0
TLS2_k127_5933117_5 Pectinacetylesterase - - - 6.195e-225 709.0
TLS2_k127_5933117_6 Luciferase-like monooxygenase - - - 1.974e-201 638.0
TLS2_k127_5933117_7 Amidohydrolase family K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 616.0
TLS2_k127_5933117_8 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 546.0
TLS2_k127_5933117_9 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 540.0
TLS2_k127_5939237_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1700.0
TLS2_k127_5939237_1 acetolactate synthase K01576,K01652 - 2.2.1.6,4.1.1.7 1.392e-279 869.0
TLS2_k127_5939237_10 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 371.0
TLS2_k127_5939237_11 Sulfate ABC transporter inner membrane subunit CysT K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 362.0
TLS2_k127_5939237_12 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 324.0
TLS2_k127_5939237_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004965 273.0
TLS2_k127_5939237_14 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000009572 238.0
TLS2_k127_5939237_15 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000003231 213.0
TLS2_k127_5939237_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000001015 194.0
TLS2_k127_5939237_17 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000008285 198.0
TLS2_k127_5939237_18 DUF1704 - - - 0.00000001096 61.0
TLS2_k127_5939237_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.806e-262 822.0
TLS2_k127_5939237_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.756e-243 763.0
TLS2_k127_5939237_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 4.279e-218 685.0
TLS2_k127_5939237_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 509.0
TLS2_k127_5939237_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 477.0
TLS2_k127_5939237_7 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 461.0
TLS2_k127_5939237_8 transcription factor binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 476.0
TLS2_k127_5939237_9 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 364.0
TLS2_k127_5962902_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1374.0
TLS2_k127_5962902_1 Peptidase family M1 domain K01256 - 3.4.11.2 0.0 1044.0
TLS2_k127_5962902_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 496.0
TLS2_k127_5962902_11 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 497.0
TLS2_k127_5962902_12 COG0618 Exopolyphosphatase-related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 488.0
TLS2_k127_5962902_13 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 438.0
TLS2_k127_5962902_14 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 439.0
TLS2_k127_5962902_15 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 417.0
TLS2_k127_5962902_16 SMART protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 415.0
TLS2_k127_5962902_17 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 377.0
TLS2_k127_5962902_18 Binding-protein-dependent transport system inner membrane component K02050,K15599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 326.0
TLS2_k127_5962902_19 COG0076 Glutamate decarboxylase and related PLP-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 324.0
TLS2_k127_5962902_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 1.328e-303 942.0
TLS2_k127_5962902_20 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily K00145,K05829 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 325.0
TLS2_k127_5962902_21 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 304.0
TLS2_k127_5962902_22 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006106 285.0
TLS2_k127_5962902_23 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000005186 271.0
TLS2_k127_5962902_24 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000282 249.0
TLS2_k127_5962902_25 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000002779 220.0
TLS2_k127_5962902_26 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000003654 217.0
TLS2_k127_5962902_27 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000002692 204.0
TLS2_k127_5962902_28 two component, sigma54 specific, transcriptional regulator, Fis family K10941 - - 0.000000000000000000000000000000000000000000000000000005294 205.0
TLS2_k127_5962902_29 - - - - 0.0000000000000000000000000000000000000000000000001127 189.0
TLS2_k127_5962902_3 Putative modulator of DNA gyrase K03568 - - 3.017e-260 838.0
TLS2_k127_5962902_31 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000008477 128.0
TLS2_k127_5962902_4 Belongs to the thiolase family K07508 - 2.3.1.16 3.143e-221 691.0
TLS2_k127_5962902_5 sigma54 specific, transcriptional regulator, Fis family - - - 3.165e-211 668.0
TLS2_k127_5962902_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 601.0
TLS2_k127_5962902_7 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 590.0
TLS2_k127_5962902_8 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 601.0
TLS2_k127_5962902_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 557.0
TLS2_k127_5970006_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.278e-219 694.0
TLS2_k127_5970006_1 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 472.0
TLS2_k127_5970006_11 HEPN domain - - - 0.0000004155 54.0
TLS2_k127_5970006_12 S23 ribosomal protein - - - 0.00004373 53.0
TLS2_k127_5970006_13 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00009713 50.0
TLS2_k127_5970006_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 419.0
TLS2_k127_5970006_3 Aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 365.0
TLS2_k127_5970006_4 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 291.0
TLS2_k127_5970006_5 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006247 263.0
TLS2_k127_5970006_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000001406 191.0
TLS2_k127_5970006_9 COG5640 Secreted trypsin-like serine protease - - - 0.000000000000000000000000000008255 130.0
TLS2_k127_5981735_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.551e-269 847.0
TLS2_k127_5981735_1 PFAM sigma-54 factor interaction domain-containing protein K07715 - - 2.59e-227 713.0
TLS2_k127_5981735_2 Carboxypeptidase regulatory-like domain - - - 3.52e-221 724.0
TLS2_k127_5981735_3 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 473.0
TLS2_k127_5981735_4 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 345.0
TLS2_k127_5981735_5 diguanylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 337.0
TLS2_k127_5981735_6 Homologues of snake disintegrins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002233 271.0
TLS2_k127_5981735_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000004548 148.0
TLS2_k127_5981735_8 Copper binding periplasmic protein CusF - - - 0.000000000000000005592 89.0
TLS2_k127_5981735_9 amine dehydrogenase activity K13372,K15229 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.4.9.1,1.4.9.2 0.0000000002233 61.0
TLS2_k127_600727_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1266.0
TLS2_k127_600727_1 PFAM Protein kinase domain - - - 0.0 1134.0
TLS2_k127_600727_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.32e-225 703.0
TLS2_k127_600727_11 MlaD protein K02067 - - 2.217e-211 672.0
TLS2_k127_600727_12 Phosphoesterase - - - 3.639e-200 635.0
TLS2_k127_600727_13 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 611.0
TLS2_k127_600727_14 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 591.0
TLS2_k127_600727_15 COG1233 Phytoene dehydrogenase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 559.0
TLS2_k127_600727_16 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 548.0
TLS2_k127_600727_17 P-loop Domain of unknown function (DUF2791) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 535.0
TLS2_k127_600727_18 protein kinase activity K01972,K02342 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 525.0
TLS2_k127_600727_19 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 516.0
TLS2_k127_600727_2 4Fe-4S dicluster domain - - - 0.0 1129.0
TLS2_k127_600727_20 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 491.0
TLS2_k127_600727_21 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 494.0
TLS2_k127_600727_22 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 486.0
TLS2_k127_600727_23 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 478.0
TLS2_k127_600727_24 TIGRFAM YidE YbjL duplication K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008762 482.0
TLS2_k127_600727_25 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 461.0
TLS2_k127_600727_26 Zinc metalloprotease (Elastase) K01400,K08604 - 3.4.24.25,3.4.24.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 461.0
TLS2_k127_600727_27 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 437.0
TLS2_k127_600727_28 Crp-like helix-turn-helix domain K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 420.0
TLS2_k127_600727_29 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 418.0
TLS2_k127_600727_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.25e-317 990.0
TLS2_k127_600727_30 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 383.0
TLS2_k127_600727_31 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 371.0
TLS2_k127_600727_32 belongs to the thioredoxin family K00384,K02453,K11912,K14949,K20543 - 1.8.1.9,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 368.0
TLS2_k127_600727_33 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 340.0
TLS2_k127_600727_34 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 338.0
TLS2_k127_600727_35 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 338.0
TLS2_k127_600727_36 PglZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 361.0
TLS2_k127_600727_37 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 321.0
TLS2_k127_600727_38 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 295.0
TLS2_k127_600727_39 Cytosol aminopeptidase family, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000866 274.0
TLS2_k127_600727_4 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 3.095e-292 956.0
TLS2_k127_600727_40 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000006116 262.0
TLS2_k127_600727_41 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006824 259.0
TLS2_k127_600727_42 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002608 248.0
TLS2_k127_600727_43 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000003145 243.0
TLS2_k127_600727_44 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001286 255.0
TLS2_k127_600727_45 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002224 239.0
TLS2_k127_600727_46 Ion transport protein K08714 - - 0.000000000000000000000000000000000000000000000000000000000000000004239 235.0
TLS2_k127_600727_47 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000007886 250.0
TLS2_k127_600727_48 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000006694 233.0
TLS2_k127_600727_49 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000007524 205.0
TLS2_k127_600727_5 Nuclease-related domain - - - 7.158e-274 894.0
TLS2_k127_600727_50 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000009968 193.0
TLS2_k127_600727_51 phosphorelay signal transduction system K15012 - - 0.00000000000000000000000000000000000000000000006382 171.0
TLS2_k127_600727_52 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000001625 159.0
TLS2_k127_600727_53 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000006453 160.0
TLS2_k127_600727_54 PFAM Archaeal ATPase - - - 0.000000000000000000000000000000000000009459 147.0
TLS2_k127_600727_56 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000008018 112.0
TLS2_k127_600727_58 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000000006149 102.0
TLS2_k127_600727_59 Thiamine biosynthesis K03154 - - 0.0000000000000000006834 89.0
TLS2_k127_600727_6 DNA-dependent DNA replication - - - 5.557e-270 875.0
TLS2_k127_600727_61 TIGRFAM DNA binding domain protein, excisionase family - - - 0.0000000000005005 71.0
TLS2_k127_600727_7 ABC transporter transmembrane region K06147 - - 2.862e-269 844.0
TLS2_k127_600727_8 COG1002 Type II restriction enzyme, methylase subunits - - - 1.492e-254 852.0
TLS2_k127_600727_9 DEAD DEAH box helicase domain protein K03724 - - 6.361e-232 738.0
TLS2_k127_601164_0 TonB dependent receptor K02014 - - 0.0 1221.0
TLS2_k127_601164_1 FtsX-like permease family K02004 - - 2.173e-291 925.0
TLS2_k127_601164_10 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 533.0
TLS2_k127_601164_11 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 531.0
TLS2_k127_601164_12 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 543.0
TLS2_k127_601164_13 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 539.0
TLS2_k127_601164_14 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 530.0
TLS2_k127_601164_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 486.0
TLS2_k127_601164_16 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 456.0
TLS2_k127_601164_17 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 448.0
TLS2_k127_601164_18 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 473.0
TLS2_k127_601164_2 Domain of unknown function (DUF3427) - - - 1.488e-278 889.0
TLS2_k127_601164_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 397.0
TLS2_k127_601164_21 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 416.0
TLS2_k127_601164_22 Saccharopine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 391.0
TLS2_k127_601164_23 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 385.0
TLS2_k127_601164_24 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 378.0
TLS2_k127_601164_25 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 347.0
TLS2_k127_601164_26 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 359.0
TLS2_k127_601164_27 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 311.0
TLS2_k127_601164_28 nUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 287.0
TLS2_k127_601164_29 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001594 295.0
TLS2_k127_601164_3 Amylo-alpha-1,6-glucosidase - - - 1.717e-248 787.0
TLS2_k127_601164_30 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003571 265.0
TLS2_k127_601164_31 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000008008 256.0
TLS2_k127_601164_32 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006051 258.0
TLS2_k127_601164_33 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000007784 243.0
TLS2_k127_601164_35 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000002526 187.0
TLS2_k127_601164_36 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000000000000005368 186.0
TLS2_k127_601164_37 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000003448 177.0
TLS2_k127_601164_38 - - - - 0.000000000000000000000000000000000000000000002623 175.0
TLS2_k127_601164_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000000000004485 158.0
TLS2_k127_601164_4 Bacterial regulatory protein, Fis family - - - 6.778e-231 721.0
TLS2_k127_601164_40 Band 7 protein K07192 - - 0.0000000000000000000000000000000000000008388 169.0
TLS2_k127_601164_41 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K05576 - 1.6.5.3 0.000000000000000000000000000000000000001142 158.0
TLS2_k127_601164_42 - - - - 0.000000000000000000000000000000000005461 149.0
TLS2_k127_601164_43 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000002565 137.0
TLS2_k127_601164_44 heme binding - - - 0.00000000000000000000000000000000003089 151.0
TLS2_k127_601164_45 - K03657,K06198 - 3.6.4.12 0.0000000000000000000000000000000006729 142.0
TLS2_k127_601164_46 bacterial-type flagellum organization K02411 - - 0.000000000000000000000000000000001633 144.0
TLS2_k127_601164_47 - - - - 0.0000000000000000000000000000005282 135.0
TLS2_k127_601164_49 - - - - 0.000000000000000000000006798 116.0
TLS2_k127_601164_5 ammonium transporter K03320 - - 2.492e-206 649.0
TLS2_k127_601164_51 Belongs to the frataxin family K06202 - - 0.00000000000000001758 87.0
TLS2_k127_601164_52 - - - - 0.00000000000000005905 94.0
TLS2_k127_601164_53 DNA-templated transcription, initiation K03088 - - 0.0000000000000001971 88.0
TLS2_k127_601164_55 Transposase IS66 family K07484 - - 0.000000000000008709 81.0
TLS2_k127_601164_56 Domain of unknown function (DUF4360) - - - 0.000000000001137 78.0
TLS2_k127_601164_57 Involved in the tonB-independent uptake of proteins - - - 0.00000000009607 76.0
TLS2_k127_601164_59 Putative addiction module component - - - 0.000000002213 61.0
TLS2_k127_601164_6 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K03183 - 2.1.1.163,2.1.1.201,2.7.1.202 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 625.0
TLS2_k127_601164_60 Tetratricopeptide repeat - - - 0.000000002661 71.0
TLS2_k127_601164_61 Plasmid stabilization system - - - 0.0005459 48.0
TLS2_k127_601164_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 595.0
TLS2_k127_601164_8 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 601.0
TLS2_k127_601164_9 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 546.0
TLS2_k127_6188403_0 amino acid K03294,K16238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 568.0
TLS2_k127_6188403_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 497.0
TLS2_k127_6188403_10 Heat shock 70 kDa protein K04043 - - 0.000001144 61.0
TLS2_k127_6188403_11 PFAM PEGA domain - - - 0.00002464 57.0
TLS2_k127_6188403_2 Sh3 type 3 domain protein K01448,K07448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 360.0
TLS2_k127_6188403_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 299.0
TLS2_k127_6188403_4 tRNA wobble cytosine modification - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001495 273.0
TLS2_k127_6188403_5 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000002985 228.0
TLS2_k127_6188403_6 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000008458 165.0
TLS2_k127_6188403_7 - - - - 0.0000000000000000000000000005924 119.0
TLS2_k127_6188403_8 von Willebrand factor (vWF) type A domain - - - 0.0000000000001071 73.0
TLS2_k127_6188403_9 amine dehydrogenase activity K13372,K15229 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.4.9.1,1.4.9.2 0.00000000002398 64.0
TLS2_k127_6238252_0 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 562.0
TLS2_k127_6238252_1 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 563.0
TLS2_k127_6238252_10 PFAM Stage II sporulation E family protein - - - 0.0000000000000000000000000000000000000000000000000000000005736 218.0
TLS2_k127_6238252_11 - - - - 0.0000000000000000000000000000000000000000000000000009968 200.0
TLS2_k127_6238252_12 Universal stress protein - - - 0.0000000000000000000000000000000000000000000007088 184.0
TLS2_k127_6238252_14 OmpA family K02557 - - 0.00000000000000000000000000000000000000000004493 171.0
TLS2_k127_6238252_15 sequence-specific DNA binding K07729 - - 0.00000000000000000000000000000000000005027 147.0
TLS2_k127_6238252_2 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 497.0
TLS2_k127_6238252_3 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 509.0
TLS2_k127_6238252_4 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 418.0
TLS2_k127_6238252_5 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 347.0
TLS2_k127_6238252_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 318.0
TLS2_k127_6238252_8 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 297.0
TLS2_k127_6238252_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002306 286.0
TLS2_k127_627632_0 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 501.0
TLS2_k127_627632_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 392.0
TLS2_k127_627632_2 Peptidase inhibitor I9 K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 403.0
TLS2_k127_627632_3 Fructosamine kinase - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 366.0
TLS2_k127_627632_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 347.0
TLS2_k127_627632_5 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 289.0
TLS2_k127_627632_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000009976 211.0
TLS2_k127_627632_8 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000000000000000000000000001042 144.0
TLS2_k127_6295963_0 Polyketide synthase modules and related proteins K13613,K13614 - - 0.0 1662.0
TLS2_k127_6295963_1 histidine kinase A domain protein - - - 8.351e-217 699.0
TLS2_k127_6295963_10 Acyl transferase domain K00645,K15327,K15329,K15469 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 373.0
TLS2_k127_6295963_11 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 351.0
TLS2_k127_6295963_12 ABC-type multidrug transport system ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 329.0
TLS2_k127_6295963_13 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000000000749 158.0
TLS2_k127_6295963_14 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000002332 162.0
TLS2_k127_6295963_15 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000114 152.0
TLS2_k127_6295963_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 9.275e-215 684.0
TLS2_k127_6295963_3 2-Nitropropane dioxygenase K15329 - - 1.449e-212 668.0
TLS2_k127_6295963_4 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 624.0
TLS2_k127_6295963_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 581.0
TLS2_k127_6295963_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 535.0
TLS2_k127_6295963_7 Non-ribosomal peptide synthetase modules and related proteins K13611,K13614,K15654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 520.0
TLS2_k127_6295963_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 476.0
TLS2_k127_6295963_9 synthase K13614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 417.0
TLS2_k127_6529232_0 - - - - 1.464e-217 683.0
TLS2_k127_6529232_1 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 2.416e-207 656.0
TLS2_k127_6529232_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 530.0
TLS2_k127_6529232_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 406.0
TLS2_k127_6529232_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 315.0
TLS2_k127_6529232_5 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000373 277.0
TLS2_k127_6529232_6 Aminotransferase K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001492 295.0
TLS2_k127_6529232_7 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003512 277.0
TLS2_k127_6529232_8 PFAM Haloacid dehalogenase domain protein hydrolase K02566 - - 0.0000000000000000000000000000000000000000000000000000000000003058 222.0
TLS2_k127_6529232_9 modulation by symbiont of host adenylate cyclase-mediated signal transduction K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000399 214.0
TLS2_k127_6548824_0 Protein involved in cellulose biosynthesis - - - 9.315e-237 760.0
TLS2_k127_6548824_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 1.046e-233 728.0
TLS2_k127_6548824_10 membrane protein (DUF2231) - - - 0.00000000000000000000000000000000000000000000000002407 184.0
TLS2_k127_6548824_12 - - - - 0.000000000000056 82.0
TLS2_k127_6548824_2 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 481.0
TLS2_k127_6548824_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 484.0
TLS2_k127_6548824_4 ABC transporter, ATP-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 358.0
TLS2_k127_6548824_5 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 331.0
TLS2_k127_6548824_6 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 332.0
TLS2_k127_6548824_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 321.0
TLS2_k127_6548824_8 PFAM Redoxin - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 302.0
TLS2_k127_6548824_9 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002453 281.0
TLS2_k127_6564921_0 serine threonine protein kinase - - - 3.493e-279 910.0
TLS2_k127_6564921_1 Calcineurin-like phosphoesterase - - - 4.059e-266 840.0
TLS2_k127_6564921_10 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000000000006447 165.0
TLS2_k127_6564921_2 Neutral/alkaline non-lysosomal ceramidase, C-terminal K12349 - 3.5.1.23 2.434e-260 820.0
TLS2_k127_6564921_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.085e-256 800.0
TLS2_k127_6564921_4 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 5.224e-216 683.0
TLS2_k127_6564921_5 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 587.0
TLS2_k127_6564921_6 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 377.0
TLS2_k127_6564921_7 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 377.0
TLS2_k127_6564921_8 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619,K01840 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4,5.4.2.8 0.00000000000000000000000000000000000000000000002764 173.0
TLS2_k127_6564921_9 rna polymerase sigma factor - - - 0.000000000000000000000000000000000000000000000822 174.0
TLS2_k127_6587842_0 oxidoreductase activity K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 443.0
TLS2_k127_6587842_1 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 411.0
TLS2_k127_6587842_2 Belongs to the amidase family K19176 - 3.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 385.0
TLS2_k127_6587842_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001678 264.0
TLS2_k127_6587842_4 PFAM Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000008571 188.0
TLS2_k127_6587842_5 Bacterial Ig-like domain (group 3) - - - 0.000000000000000000000000000000002477 149.0
TLS2_k127_6587842_6 - - - - 0.00000000003069 76.0
TLS2_k127_6587842_7 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.00000005156 66.0
TLS2_k127_6587842_8 peptidase M4 thermolysin K01399,K08604 GO:0005575,GO:0005576 3.4.24.25,3.4.24.26 0.000002466 61.0
TLS2_k127_6587842_9 23S rRNA-intervening sequence protein - - - 0.0001108 53.0
TLS2_k127_6601870_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2228.0
TLS2_k127_6601870_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1429.0
TLS2_k127_6601870_10 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 456.0
TLS2_k127_6601870_11 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 432.0
TLS2_k127_6601870_12 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 423.0
TLS2_k127_6601870_13 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 413.0
TLS2_k127_6601870_14 Family membership - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 393.0
TLS2_k127_6601870_15 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 294.0
TLS2_k127_6601870_16 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008378 297.0
TLS2_k127_6601870_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004525 262.0
TLS2_k127_6601870_19 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000009782 203.0
TLS2_k127_6601870_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0 1027.0
TLS2_k127_6601870_20 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000005116 199.0
TLS2_k127_6601870_21 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000009996 193.0
TLS2_k127_6601870_22 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000002679 201.0
TLS2_k127_6601870_23 Ca2 -binding protein (EF-Hand superfamily K17991 - 1.11.2.3 0.00000000000000000000000000000000000000000000001505 181.0
TLS2_k127_6601870_24 DoxX K15977 - - 0.0000000000000000000000000000000000000000003023 163.0
TLS2_k127_6601870_25 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000000005106 161.0
TLS2_k127_6601870_28 phage tail tape measure protein - - - 0.0000000000000000000000000000000000000001865 175.0
TLS2_k127_6601870_29 - - - - 0.0000000000000000000000000000002958 126.0
TLS2_k127_6601870_3 GAF domain - - - 1.642e-241 758.0
TLS2_k127_6601870_30 Band 7 protein K07192 - - 0.000000000000000000000001435 123.0
TLS2_k127_6601870_31 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000000000006832 100.0
TLS2_k127_6601870_32 - - - - 0.0000000000000000007561 89.0
TLS2_k127_6601870_33 Rhodopirellula transposase DDE domain - - - 0.00000000000000007252 85.0
TLS2_k127_6601870_35 DNA binding domain with preference for A/T rich regions - - - 0.00000003992 63.0
TLS2_k127_6601870_36 - - - - 0.000002605 62.0
TLS2_k127_6601870_4 Aminotransferase K01845 - 5.4.3.8 1.775e-218 685.0
TLS2_k127_6601870_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.665e-211 664.0
TLS2_k127_6601870_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 3.977e-200 653.0
TLS2_k127_6601870_7 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 525.0
TLS2_k127_6601870_8 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 487.0
TLS2_k127_6601870_9 energy transducer activity K02487,K03832,K06596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 474.0
TLS2_k127_6619178_0 Penicillin amidase K01434 - 3.5.1.11 1.295e-307 971.0
TLS2_k127_6619178_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 6.12e-296 930.0
TLS2_k127_6619178_10 Pfam:HxxPF_rpt - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 547.0
TLS2_k127_6619178_11 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 512.0
TLS2_k127_6619178_12 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.5.2,1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 490.0
TLS2_k127_6619178_13 RmlD substrate binding domain K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 484.0
TLS2_k127_6619178_14 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 426.0
TLS2_k127_6619178_16 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 352.0
TLS2_k127_6619178_17 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 352.0
TLS2_k127_6619178_18 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 345.0
TLS2_k127_6619178_19 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 354.0
TLS2_k127_6619178_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 9.273e-244 766.0
TLS2_k127_6619178_20 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 333.0
TLS2_k127_6619178_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001027 250.0
TLS2_k127_6619178_22 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009497 250.0
TLS2_k127_6619178_23 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000000000000000000000000004532 219.0
TLS2_k127_6619178_24 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 0.0000000000000000000000000000000000000000000000000002499 212.0
TLS2_k127_6619178_25 Glutathione S-transferase K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000007548 170.0
TLS2_k127_6619178_26 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000005161 164.0
TLS2_k127_6619178_27 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000000000000000000000005271 152.0
TLS2_k127_6619178_28 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000009992 158.0
TLS2_k127_6619178_29 - - - - 0.0000000000000000000000000000000000000007016 153.0
TLS2_k127_6619178_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 1.979e-225 706.0
TLS2_k127_6619178_30 regulation of translation K03530,K05788 - - 0.000000000000000000000000000000000000001121 149.0
TLS2_k127_6619178_31 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000000009045 157.0
TLS2_k127_6619178_32 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000000000000001393 134.0
TLS2_k127_6619178_33 PFAM WD40 repeat, subgroup - - - 0.0000000000000000000000005308 121.0
TLS2_k127_6619178_35 Belongs to the Dps family - - - 0.0000000444 64.0
TLS2_k127_6619178_36 PFAM NLP P60 protein K11060,K21471 - - 0.000371 54.0
TLS2_k127_6619178_37 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0004382 53.0
TLS2_k127_6619178_4 histidyl-tRNA synthetase K01892 - 6.1.1.21 1.542e-199 636.0
TLS2_k127_6619178_5 Zinc metalloprotease (Elastase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 613.0
TLS2_k127_6619178_6 COG4992 Ornithine acetylornithine aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 599.0
TLS2_k127_6619178_7 COGs COG1620 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 572.0
TLS2_k127_6619178_8 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 573.0
TLS2_k127_6619178_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 562.0
TLS2_k127_6627237_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.906e-303 939.0
TLS2_k127_6627237_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 598.0
TLS2_k127_6627237_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002422 246.0
TLS2_k127_6627237_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000002093 228.0
TLS2_k127_6627237_12 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000002355 163.0
TLS2_k127_6627237_13 zinc-finger binding domain of transposase IS66 K07484 - - 0.0000000000000000000000000000000001088 145.0
TLS2_k127_6627237_14 COG3209 Rhs family protein - - - 0.00000000000000000000000001355 123.0
TLS2_k127_6627237_15 Belongs to the BolA IbaG family - - - 0.0000000000000000000000009347 119.0
TLS2_k127_6627237_16 - - - - 0.0000000000000000000002996 99.0
TLS2_k127_6627237_17 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000001208 108.0
TLS2_k127_6627237_18 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000601 90.0
TLS2_k127_6627237_2 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 419.0
TLS2_k127_6627237_21 - - - - 0.000000009039 64.0
TLS2_k127_6627237_22 fumarate reductase K00239 - 1.3.5.1,1.3.5.4 0.0000001455 64.0
TLS2_k127_6627237_24 23S rRNA-intervening sequence protein - - - 0.000005261 53.0
TLS2_k127_6627237_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 403.0
TLS2_k127_6627237_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 386.0
TLS2_k127_6627237_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 384.0
TLS2_k127_6627237_6 PFAM Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 368.0
TLS2_k127_6627237_7 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 328.0
TLS2_k127_6627237_8 Lipase (class 2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 314.0
TLS2_k127_6627237_9 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 307.0
TLS2_k127_6627267_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1313.0
TLS2_k127_6627267_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1146.0
TLS2_k127_6627267_10 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 421.0
TLS2_k127_6627267_11 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 404.0
TLS2_k127_6627267_12 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 358.0
TLS2_k127_6627267_13 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 338.0
TLS2_k127_6627267_14 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 317.0
TLS2_k127_6627267_16 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005225 290.0
TLS2_k127_6627267_17 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005477 276.0
TLS2_k127_6627267_18 Belongs to the SfsA family K06206 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001309 264.0
TLS2_k127_6627267_19 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003384 252.0
TLS2_k127_6627267_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 7.313e-236 740.0
TLS2_k127_6627267_20 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000003244 245.0
TLS2_k127_6627267_21 Nudix hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000009996 211.0
TLS2_k127_6627267_22 - - - - 0.00000000000000000000000000000000000000000000000000000000002757 209.0
TLS2_k127_6627267_23 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000001188 216.0
TLS2_k127_6627267_24 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000003475 216.0
TLS2_k127_6627267_25 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000002852 190.0
TLS2_k127_6627267_27 SUF system FeS assembly protein K04488 - - 0.0000000000000000000000000000000000302 143.0
TLS2_k127_6627267_28 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000005654 138.0
TLS2_k127_6627267_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 598.0
TLS2_k127_6627267_30 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000002468 117.0
TLS2_k127_6627267_31 Glyoxalase-like domain K06996 - - 0.00000000000000000000008167 103.0
TLS2_k127_6627267_32 PFAM AIG2 family protein - - - 0.000000000000000001079 98.0
TLS2_k127_6627267_33 - - - - 0.000000000000000002093 86.0
TLS2_k127_6627267_34 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000001854 73.0
TLS2_k127_6627267_35 ABC-2 family transporter protein - - - 0.0000000000159 75.0
TLS2_k127_6627267_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000001358 59.0
TLS2_k127_6627267_37 Transposase IS66 family K07484 - - 0.00000006533 59.0
TLS2_k127_6627267_38 - - - - 0.00000372 50.0
TLS2_k127_6627267_4 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 591.0
TLS2_k127_6627267_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 550.0
TLS2_k127_6627267_6 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 540.0
TLS2_k127_6627267_8 Transcriptional regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 484.0
TLS2_k127_6627267_9 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 471.0
TLS2_k127_6627628_0 PFAM AAA ATPase central domain protein - - - 0.0 1262.0
TLS2_k127_6627628_1 Alpha amylase, catalytic domain - - - 0.0 1261.0
TLS2_k127_6627628_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 379.0
TLS2_k127_6627628_11 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 289.0
TLS2_k127_6627628_13 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000484 257.0
TLS2_k127_6627628_15 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000001281 239.0
TLS2_k127_6627628_16 PFAM Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000375 231.0
TLS2_k127_6627628_17 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000001535 215.0
TLS2_k127_6627628_18 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000003808 203.0
TLS2_k127_6627628_19 rna polymerase sigma factor - - - 0.000000000000000000000000000000000000000000000007269 180.0
TLS2_k127_6627628_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1036.0
TLS2_k127_6627628_20 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000002571 155.0
TLS2_k127_6627628_21 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000001495 132.0
TLS2_k127_6627628_22 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000001025 131.0
TLS2_k127_6627628_23 bacterial-type flagellum organization - - - 0.00000000000000000000000009625 113.0
TLS2_k127_6627628_3 SMART serine threonine protein kinase K12132 - 2.7.11.1 1.055e-288 919.0
TLS2_k127_6627628_4 Bacterial regulatory protein, Fis family K07713 - - 3.281e-221 693.0
TLS2_k127_6627628_5 TPR repeat - - - 2.288e-212 704.0
TLS2_k127_6627628_6 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 548.0
TLS2_k127_6627628_7 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 469.0
TLS2_k127_6627628_8 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 469.0
TLS2_k127_6627628_9 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 374.0
TLS2_k127_669253_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1237.0
TLS2_k127_669253_1 Transglycosylase SLT domain K08309 - - 0.0 1028.0
TLS2_k127_669253_10 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 560.0
TLS2_k127_669253_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 540.0
TLS2_k127_669253_12 Protein of unknown function (DUF819) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 541.0
TLS2_k127_669253_13 Serine/threonine phosphatases, family 2C, catalytic domain K01090 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 472.0
TLS2_k127_669253_14 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 494.0
TLS2_k127_669253_15 Na Pi-cotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 475.0
TLS2_k127_669253_16 Serine/threonine phosphatases, family 2C, catalytic domain K01090 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 456.0
TLS2_k127_669253_17 Domain of unknown function (DUF368) K08974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 423.0
TLS2_k127_669253_18 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 413.0
TLS2_k127_669253_19 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 407.0
TLS2_k127_669253_2 Glycogen debranching enzyme N terminal - - - 2.104e-275 863.0
TLS2_k127_669253_20 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 408.0
TLS2_k127_669253_21 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 411.0
TLS2_k127_669253_22 Belongs to the methyltransferase superfamily K06969,K12297 - 2.1.1.173,2.1.1.191,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 413.0
TLS2_k127_669253_23 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 393.0
TLS2_k127_669253_24 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 381.0
TLS2_k127_669253_25 PFAM ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 397.0
TLS2_k127_669253_26 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 350.0
TLS2_k127_669253_27 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 345.0
TLS2_k127_669253_28 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 339.0
TLS2_k127_669253_29 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 343.0
TLS2_k127_669253_3 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.753e-271 850.0
TLS2_k127_669253_30 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 301.0
TLS2_k127_669253_31 Heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 307.0
TLS2_k127_669253_34 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003716 257.0
TLS2_k127_669253_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004851 250.0
TLS2_k127_669253_36 photoreceptor activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000007335 264.0
TLS2_k127_669253_37 protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001111 253.0
TLS2_k127_669253_38 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000192 251.0
TLS2_k127_669253_39 pectinesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000005528 252.0
TLS2_k127_669253_4 Carboxypeptidase regulatory-like domain - - - 8.033e-255 821.0
TLS2_k127_669253_40 Belongs to the GbsR family - - - 0.000000000000000000000000000000000000000000000000000000000000000005038 230.0
TLS2_k127_669253_41 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000005854 233.0
TLS2_k127_669253_42 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000001616 215.0
TLS2_k127_669253_44 Belongs to the P-Pant transferase superfamily K02362,K06133 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008897,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009366,GO:0009712,GO:0009713,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 6.3.2.14 0.000000000000000000000000000000000000000000000000000000000009917 214.0
TLS2_k127_669253_45 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000003843 216.0
TLS2_k127_669253_47 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.000000000000000000000000000000000000000000000000000000001455 203.0
TLS2_k127_669253_48 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000000002557 211.0
TLS2_k127_669253_49 Protein of unknown function (DUF455) - - - 0.00000000000000000000000000000000000000000000000000000002124 206.0
TLS2_k127_669253_5 OPT oligopeptide transporter protein - - - 1.827e-205 675.0
TLS2_k127_669253_50 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000002874 211.0
TLS2_k127_669253_51 cheY-homologous receiver domain K07773 - - 0.0000000000000000000000000000000000000000000000000000005582 196.0
TLS2_k127_669253_52 PhoD-like phosphatase - - - 0.0000000000000000000000000000000000000000003084 176.0
TLS2_k127_669253_54 CRS1_YhbY K07574 - - 0.000000000000000000000000000000005286 134.0
TLS2_k127_669253_57 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000001872 123.0
TLS2_k127_669253_58 SnoaL-like polyketide cyclase - - - 0.00000000000000000000001687 113.0
TLS2_k127_669253_59 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000000000000000671 101.0
TLS2_k127_669253_6 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 592.0
TLS2_k127_669253_61 Domain of unknown function (DUF309) K09763 - - 0.000000000000000001 93.0
TLS2_k127_669253_62 GAF modulated sigma54 specific transcriptional regulator, Fis family K21405 - - 0.000006244 57.0
TLS2_k127_669253_63 YceI-like domain - - - 0.00004571 52.0
TLS2_k127_669253_7 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 600.0
TLS2_k127_669253_8 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 584.0
TLS2_k127_669253_9 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 573.0
TLS2_k127_675255_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1664.0
TLS2_k127_675255_1 AAA C-terminal domain K07478 - - 1.158e-207 656.0
TLS2_k127_675255_10 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003263 293.0
TLS2_k127_675255_11 integral membrane protein K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006347 272.0
TLS2_k127_675255_12 Iron-containing redox enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000002811 231.0
TLS2_k127_675255_14 bacterial-type flagellum organization K02411 - - 0.00000000000000000000000000000000000000000002671 176.0
TLS2_k127_675255_15 endonuclease activity - - - 0.000000000000000000000000000000000001667 154.0
TLS2_k127_675255_16 hydroperoxide reductase activity - - - 0.0000000000000000000000005367 107.0
TLS2_k127_675255_18 hydroperoxide reductase activity - - - 0.000000000000000000001925 96.0
TLS2_k127_675255_19 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000002217 63.0
TLS2_k127_675255_2 PFAM amidohydrolase K01464 - 3.5.2.2 6.912e-205 662.0
TLS2_k127_675255_20 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000003034 53.0
TLS2_k127_675255_21 S23 ribosomal protein - - - 0.000005464 55.0
TLS2_k127_675255_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 623.0
TLS2_k127_675255_4 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 557.0
TLS2_k127_675255_5 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 540.0
TLS2_k127_675255_6 4Fe-4S dicluster domain K17723 - 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 525.0
TLS2_k127_675255_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 506.0
TLS2_k127_675255_8 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 331.0
TLS2_k127_675255_9 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 322.0
TLS2_k127_6757371_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1176.0
TLS2_k127_6757371_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 507.0
TLS2_k127_6757371_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008445 279.0
TLS2_k127_6757371_3 diguanylate cyclase - - - 0.00000000000008446 85.0
TLS2_k127_6768881_0 topoisomerase K02469 - 5.99.1.3 0.0 1200.0
TLS2_k127_6768881_1 Putative glutamine amidotransferase - - - 0.0 1119.0
TLS2_k127_6768881_10 CRISPR-associated protein GSU0053 (Cas_GSU0053) K19131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 589.0
TLS2_k127_6768881_11 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 592.0
TLS2_k127_6768881_12 arsenical-resistance protein K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 535.0
TLS2_k127_6768881_13 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 550.0
TLS2_k127_6768881_15 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 456.0
TLS2_k127_6768881_16 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 461.0
TLS2_k127_6768881_17 DNA modification K00571,K07317 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 470.0
TLS2_k127_6768881_18 Di-haem cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 437.0
TLS2_k127_6768881_19 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 404.0
TLS2_k127_6768881_2 DNA topoisomerase K02470,K02622 - 5.99.1.3 0.0 1049.0
TLS2_k127_6768881_20 Protein kinase domain K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 400.0
TLS2_k127_6768881_21 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 373.0
TLS2_k127_6768881_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 369.0
TLS2_k127_6768881_23 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 345.0
TLS2_k127_6768881_24 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 346.0
TLS2_k127_6768881_25 TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 344.0
TLS2_k127_6768881_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 344.0
TLS2_k127_6768881_27 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 312.0
TLS2_k127_6768881_28 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 300.0
TLS2_k127_6768881_29 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 307.0
TLS2_k127_6768881_3 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.0 1028.0
TLS2_k127_6768881_30 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 305.0
TLS2_k127_6768881_31 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 291.0
TLS2_k127_6768881_32 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) K19132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001992 289.0
TLS2_k127_6768881_33 Domain of unknown function (DUF2341) K01278,K03561 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001058 273.0
TLS2_k127_6768881_34 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000001789 237.0
TLS2_k127_6768881_36 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000004346 220.0
TLS2_k127_6768881_38 integral membrane protein (DUF2270) - - - 0.0000000000000000000000000000000000000000000000000000007586 199.0
TLS2_k127_6768881_39 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity - - - 0.000000000000000000000000000000000000000000000000000006046 205.0
TLS2_k127_6768881_4 TIGRFAM CRISPR-associated helicase Cas3 K07012 - - 9e-314 991.0
TLS2_k127_6768881_40 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000001349 195.0
TLS2_k127_6768881_41 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000001516 182.0
TLS2_k127_6768881_42 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000001283 168.0
TLS2_k127_6768881_43 - - - - 0.0000000000000000000000000000000000000009963 163.0
TLS2_k127_6768881_44 amine dehydrogenase activity - - - 0.000000000000000000000000000000000003474 152.0
TLS2_k127_6768881_45 ThiS family - - - 0.000000000000000000000000000005313 122.0
TLS2_k127_6768881_46 NUDIX domain - - - 0.000000000000000000000000000005575 134.0
TLS2_k127_6768881_47 - - - - 0.0000000000000000000000000000101 129.0
TLS2_k127_6768881_48 Rhodanese Homology Domain - - - 0.0000000000000000000000001324 109.0
TLS2_k127_6768881_49 Transcriptional regulator, AbiEi antitoxin, Type IV TA system - - - 0.000000000000000000000000151 119.0
TLS2_k127_6768881_5 ABC transporter C-terminal domain K06158 - - 1.109e-303 944.0
TLS2_k127_6768881_51 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669,K07672 - - 0.0000000000000000000008577 109.0
TLS2_k127_6768881_52 Heavy-metal resistance - - - 0.000000000000000009929 92.0
TLS2_k127_6768881_53 M6 family metalloprotease domain protein - - - 0.000000000000003842 90.0
TLS2_k127_6768881_54 Produces ATP from ADP in the presence of a proton gradient across the membrane K02132 GO:0000166,GO:0000275,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005754,GO:0005759,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006839,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009295,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016310,GO:0016469,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0030554,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042645,GO:0042776,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045259,GO:0045261,GO:0045267,GO:0046034,GO:0046390,GO:0046483,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0055086,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902600,GO:1990542 - 0.00000000000005288 71.0
TLS2_k127_6768881_56 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000001315 64.0
TLS2_k127_6768881_57 bacterial-type flagellum organization K02411 - - 0.0001369 51.0
TLS2_k127_6768881_6 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 2.142e-285 890.0
TLS2_k127_6768881_7 Zn_pept - - - 5.839e-272 851.0
TLS2_k127_6768881_8 AMP-binding enzyme C-terminal domain K00666,K20034 - 6.2.1.44 9.705e-257 803.0
TLS2_k127_6768881_9 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 594.0
TLS2_k127_6787497_0 AAA ATPase domain - - - 0.0 1201.0
TLS2_k127_6787497_1 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 0.0 1110.0
TLS2_k127_6787497_10 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 402.0
TLS2_k127_6787497_11 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 396.0
TLS2_k127_6787497_12 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 389.0
TLS2_k127_6787497_13 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 383.0
TLS2_k127_6787497_14 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 356.0
TLS2_k127_6787497_16 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 299.0
TLS2_k127_6787497_17 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 301.0
TLS2_k127_6787497_18 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 304.0
TLS2_k127_6787497_19 heme binding K21472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002257 284.0
TLS2_k127_6787497_2 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 4.063e-242 758.0
TLS2_k127_6787497_20 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004523 265.0
TLS2_k127_6787497_21 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000001633 254.0
TLS2_k127_6787497_23 Cupin-like domain - - - 0.00000000000000000000000000000000000000000000000521 185.0
TLS2_k127_6787497_24 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000008942 184.0
TLS2_k127_6787497_25 universal stress protein - - - 0.0000000000000000000000000000000000000000001295 170.0
TLS2_k127_6787497_26 - - - - 0.00000000000000000000000000000000000000004992 164.0
TLS2_k127_6787497_28 Cas6 Crispr - - - 0.0000000000000000000000003491 119.0
TLS2_k127_6787497_3 CRISPR-associated helicase, Cas3 K07012 - - 8.454e-234 767.0
TLS2_k127_6787497_30 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000002415 99.0
TLS2_k127_6787497_31 TIGRFAM CRISPR-associated protein Cas5, N-terminal domain K19090 - - 0.0000000000000000004639 92.0
TLS2_k127_6787497_32 PFAM Rhodanese domain protein - - - 0.0000001269 61.0
TLS2_k127_6787497_33 zinc-ribbon domain - - - 0.00001016 52.0
TLS2_k127_6787497_4 4Fe-4S single cluster domain K06871 - - 2.291e-203 644.0
TLS2_k127_6787497_5 Uncharacterized protein conserved in bacteria (DUF2330) - - - 2.332e-202 647.0
TLS2_k127_6787497_6 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 621.0
TLS2_k127_6787497_7 Response regulator, receiver K02657,K20972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 493.0
TLS2_k127_6787497_8 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 433.0
TLS2_k127_6787497_9 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 422.0
TLS2_k127_6817345_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1428.0
TLS2_k127_6817345_1 heat shock protein 70 K04043 - - 0.0 1041.0
TLS2_k127_6817345_10 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 329.0
TLS2_k127_6817345_11 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001238 289.0
TLS2_k127_6817345_12 AAA domain K06926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001858 273.0
TLS2_k127_6817345_13 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000008415 262.0
TLS2_k127_6817345_14 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004473 241.0
TLS2_k127_6817345_15 Domain of unknown function (DUF4188) - - - 0.00000000000000000000000000000000000000000000000000003235 193.0
TLS2_k127_6817345_16 - - - - 0.000000000000000000000000000000000000000009048 162.0
TLS2_k127_6817345_18 transporter component K07112 - - 0.000000000000000000000000000000000000005853 155.0
TLS2_k127_6817345_19 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000006925 154.0
TLS2_k127_6817345_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.159e-197 626.0
TLS2_k127_6817345_20 Evidence 4 Homologs of previously reported genes of K07112 - - 0.0000000000000000000000000000000000001366 146.0
TLS2_k127_6817345_21 - - - - 0.0000000000000000000000000000000000007125 162.0
TLS2_k127_6817345_22 WHG domain - - - 0.000000000000000000000000000000008187 135.0
TLS2_k127_6817345_23 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.000000000000000000000000000000118 128.0
TLS2_k127_6817345_24 MobA-like NTP transferase domain - - - 0.00000000000000000000000000001039 129.0
TLS2_k127_6817345_25 Tellurite resistance protein TerB - - - 0.00000000000000000000000192 114.0
TLS2_k127_6817345_26 - K07039 - - 0.000000000000000000001319 98.0
TLS2_k127_6817345_27 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000006187 91.0
TLS2_k127_6817345_28 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000009708 100.0
TLS2_k127_6817345_3 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 606.0
TLS2_k127_6817345_31 Glycosyl transferases group 1 - - - 0.00000003072 64.0
TLS2_k127_6817345_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 419.0
TLS2_k127_6817345_5 Zinc metalloprotease (Elastase) K01400,K08604 - 3.4.24.25,3.4.24.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 425.0
TLS2_k127_6817345_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 388.0
TLS2_k127_6817345_7 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 363.0
TLS2_k127_6817345_8 Zn-dependent hydrolases including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 344.0
TLS2_k127_6817345_9 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 324.0
TLS2_k127_6847910_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.529e-276 852.0
TLS2_k127_6847910_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.91e-257 799.0
TLS2_k127_6847910_11 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000216 83.0
TLS2_k127_6847910_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000002361 86.0
TLS2_k127_6847910_14 Protein of unknown function (DUF938) - - - 0.000000000009018 71.0
TLS2_k127_6847910_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000001471 65.0
TLS2_k127_6847910_16 tetratricopeptide repeat - - - 0.00005694 57.0
TLS2_k127_6847910_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 409.0
TLS2_k127_6847910_3 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 307.0
TLS2_k127_6847910_4 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000001179 211.0
TLS2_k127_6847910_5 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000002661 199.0
TLS2_k127_6847910_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000004606 195.0
TLS2_k127_6847910_8 Belongs to the peptidase S1B family K04775 - - 0.000000000000000000000000000000000002462 157.0
TLS2_k127_6847910_9 Transcriptional regulator - - - 0.000000000000000000000000000000001648 139.0
TLS2_k127_6907343_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.579e-256 812.0
TLS2_k127_6907343_1 Peptidase family M28 - - - 6.556e-202 643.0
TLS2_k127_6907343_2 with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 577.0
TLS2_k127_6907343_3 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 328.0
TLS2_k127_6907343_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 302.0
TLS2_k127_6907343_5 Beta-lactamase K18988 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 307.0
TLS2_k127_6907343_6 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000001213 207.0
TLS2_k127_6907343_8 PFAM Archaeal ATPase - - - 0.0000000000000018 76.0
TLS2_k127_6907343_9 AAA ATPase domain - - - 0.0000002193 63.0
TLS2_k127_6938507_0 TonB dependent receptor K16091 - - 6.622e-240 767.0
TLS2_k127_6938507_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 2.302e-238 799.0
TLS2_k127_6938507_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 579.0
TLS2_k127_6938507_3 Horizontally Transferred TransMembrane Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 535.0
TLS2_k127_6938507_4 Cadherin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 378.0
TLS2_k127_6938507_5 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 355.0
TLS2_k127_6938507_6 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 334.0
TLS2_k127_6938507_7 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 311.0
TLS2_k127_6938507_8 Imelysin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000348 271.0
TLS2_k127_6938507_9 Protein of unknown function (DUF4435) - - - 0.0000000000000000000000000000000000000000000000000000009361 206.0
TLS2_k127_6939860_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0 1069.0
TLS2_k127_6939860_1 helicase domain protein - - - 4.085e-292 930.0
TLS2_k127_6976362_0 Peptidase, M61 - - - 3.519e-234 745.0
TLS2_k127_6976362_1 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 4.451e-214 682.0
TLS2_k127_6976362_10 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000266 266.0
TLS2_k127_6976362_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000004946 222.0
TLS2_k127_6976362_13 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000000000106 160.0
TLS2_k127_6976362_14 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000001164 167.0
TLS2_k127_6976362_15 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000257 170.0
TLS2_k127_6976362_16 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000004463 126.0
TLS2_k127_6976362_17 domain, Protein K00525,K01952,K10953,K12516,K15125,K19231 - 1.17.4.1,6.3.5.3 0.00000000000000000000005771 108.0
TLS2_k127_6976362_18 SMI1-KNR4 cell-wall - - - 0.0000000001776 68.0
TLS2_k127_6976362_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 542.0
TLS2_k127_6976362_20 Rib/alpha-like repeat - - - 0.0002409 53.0
TLS2_k127_6976362_3 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 443.0
TLS2_k127_6976362_4 Flavin-binding monooxygenase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 440.0
TLS2_k127_6976362_5 sporulation resulting in formation of a cellular spore K06381 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 407.0
TLS2_k127_6976362_6 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 342.0
TLS2_k127_6976362_7 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 332.0
TLS2_k127_6976362_8 PilT protein domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 299.0
TLS2_k127_6976362_9 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009589 276.0
TLS2_k127_7000773_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.0 1387.0
TLS2_k127_7000773_1 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1166.0
TLS2_k127_7000773_10 Protein of unknown function DUF58 - - - 1.704e-249 781.0
TLS2_k127_7000773_11 amine dehydrogenase activity - - - 2.658e-245 807.0
TLS2_k127_7000773_12 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.742e-237 764.0
TLS2_k127_7000773_13 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 8.822e-211 661.0
TLS2_k127_7000773_14 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 3.429e-205 649.0
TLS2_k127_7000773_15 Protein of unknown function (DUF1343) - - - 3.997e-198 623.0
TLS2_k127_7000773_16 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 633.0
TLS2_k127_7000773_17 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 578.0
TLS2_k127_7000773_18 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 587.0
TLS2_k127_7000773_19 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 577.0
TLS2_k127_7000773_2 Involved in the tonB-independent uptake of proteins - - - 0.0 1058.0
TLS2_k127_7000773_20 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 565.0
TLS2_k127_7000773_21 MCM2/3/5 family K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 526.0
TLS2_k127_7000773_22 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 522.0
TLS2_k127_7000773_23 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 522.0
TLS2_k127_7000773_24 Aminotransferase, class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 475.0
TLS2_k127_7000773_25 oxidoreductase activity K08884,K11894 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 479.0
TLS2_k127_7000773_26 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 496.0
TLS2_k127_7000773_27 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 452.0
TLS2_k127_7000773_28 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 453.0
TLS2_k127_7000773_29 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 450.0
TLS2_k127_7000773_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1051.0
TLS2_k127_7000773_30 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 452.0
TLS2_k127_7000773_31 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 443.0
TLS2_k127_7000773_32 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 435.0
TLS2_k127_7000773_33 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 431.0
TLS2_k127_7000773_34 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 415.0
TLS2_k127_7000773_35 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 418.0
TLS2_k127_7000773_36 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 417.0
TLS2_k127_7000773_37 Involved in the tonB-independent uptake of proteins K12132,K20276 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 411.0
TLS2_k127_7000773_38 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 413.0
TLS2_k127_7000773_39 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 389.0
TLS2_k127_7000773_4 N-acetylmuramoyl-L-alanine amidase - - - 0.0 1029.0
TLS2_k127_7000773_40 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 424.0
TLS2_k127_7000773_42 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 361.0
TLS2_k127_7000773_43 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 362.0
TLS2_k127_7000773_44 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 358.0
TLS2_k127_7000773_45 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 357.0
TLS2_k127_7000773_46 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 339.0
TLS2_k127_7000773_47 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01029 GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 328.0
TLS2_k127_7000773_48 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 319.0
TLS2_k127_7000773_49 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 318.0
TLS2_k127_7000773_5 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 7.7e-322 1002.0
TLS2_k127_7000773_50 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 309.0
TLS2_k127_7000773_52 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 300.0
TLS2_k127_7000773_53 Succinyl-CoA 3-ketoacid-CoA transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 321.0
TLS2_k127_7000773_54 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 303.0
TLS2_k127_7000773_55 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 291.0
TLS2_k127_7000773_56 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 297.0
TLS2_k127_7000773_57 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001022 291.0
TLS2_k127_7000773_59 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003038 274.0
TLS2_k127_7000773_6 - - - - 2.066e-302 963.0
TLS2_k127_7000773_62 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000835 273.0
TLS2_k127_7000773_63 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009215 276.0
TLS2_k127_7000773_64 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001771 270.0
TLS2_k127_7000773_65 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000004264 245.0
TLS2_k127_7000773_66 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003146 258.0
TLS2_k127_7000773_68 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001088 258.0
TLS2_k127_7000773_69 peptidyl-prolyl cis-trans isomerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001263 249.0
TLS2_k127_7000773_7 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.11e-291 914.0
TLS2_k127_7000773_70 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001102 231.0
TLS2_k127_7000773_71 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000001235 246.0
TLS2_k127_7000773_74 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000003618 222.0
TLS2_k127_7000773_77 acetyltransferase K00663 - 2.3.1.82 0.0000000000000000000000000000000000000000000000000000000000001607 216.0
TLS2_k127_7000773_79 PhoD-like phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000001097 232.0
TLS2_k127_7000773_8 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.66e-281 870.0
TLS2_k127_7000773_80 to be involved in C-type cytochrome biogenesis K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000001151 219.0
TLS2_k127_7000773_82 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000001108 186.0
TLS2_k127_7000773_84 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000001182 190.0
TLS2_k127_7000773_88 Belongs to the bacterial histone-like protein family K05788 - - 0.000000000000000000000000000000000000000007706 157.0
TLS2_k127_7000773_89 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000001253 154.0
TLS2_k127_7000773_9 HD domain - - - 5.025e-260 822.0
TLS2_k127_7000773_94 rRNA binding K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000594 95.0
TLS2_k127_7000773_95 Ferredoxin K17992 - 1.12.1.3 0.00000000000000005247 94.0
TLS2_k127_7000773_98 bacterial-type flagellum organization - - - 0.0000000000005972 70.0
TLS2_k127_7000773_99 peptidyl-tyrosine autophosphorylation K03099 - - 0.0004048 53.0
TLS2_k127_7006403_0 Belongs to the ClpA ClpB family K03694 - - 6.373e-301 943.0
TLS2_k127_7006403_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 1.275e-289 899.0
TLS2_k127_7006403_10 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000001335 221.0
TLS2_k127_7006403_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000000002824 189.0
TLS2_k127_7006403_12 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000002972 190.0
TLS2_k127_7006403_13 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000364 173.0
TLS2_k127_7006403_2 PFAM AMP-dependent synthetase and ligase K04110 - 6.2.1.25 5.376e-206 666.0
TLS2_k127_7006403_3 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 575.0
TLS2_k127_7006403_4 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 491.0
TLS2_k127_7006403_5 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 385.0
TLS2_k127_7006403_6 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 364.0
TLS2_k127_7006403_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000381 265.0
TLS2_k127_7006403_8 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000004262 248.0
TLS2_k127_7006403_9 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000005984 221.0
TLS2_k127_7009700_0 NLP P60 protein - - - 0.0 1350.0
TLS2_k127_7009700_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 0.0 1228.0
TLS2_k127_7009700_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. K12266 - - 1.724e-217 689.0
TLS2_k127_7009700_11 Belongs to the ompA family - - - 6.384e-217 686.0
TLS2_k127_7009700_12 CRISPR-associated helicase, Cas3 K07012 - - 7.988e-206 672.0
TLS2_k127_7009700_13 Beta-L-arabinofuranosidase, GH127 - - - 9.521e-205 653.0
TLS2_k127_7009700_14 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 1.507e-201 655.0
TLS2_k127_7009700_15 Major Facilitator Superfamily - - - 1.764e-197 627.0
TLS2_k127_7009700_16 dna ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 593.0
TLS2_k127_7009700_17 PFAM type III restriction protein res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 485.0
TLS2_k127_7009700_18 - K19136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 501.0
TLS2_k127_7009700_19 Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 475.0
TLS2_k127_7009700_2 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0 1141.0
TLS2_k127_7009700_20 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 391.0
TLS2_k127_7009700_21 protein methyltransferase activity K00568,K02687 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 388.0
TLS2_k127_7009700_22 CRISPR-associated protein GSU0053 (Cas_GSU0053) K19131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 364.0
TLS2_k127_7009700_23 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 324.0
TLS2_k127_7009700_24 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 306.0
TLS2_k127_7009700_25 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 308.0
TLS2_k127_7009700_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 297.0
TLS2_k127_7009700_27 PFAM CRISPR-associated protein, GSU0054 family (Cas_GSU0054) K19132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 316.0
TLS2_k127_7009700_28 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 295.0
TLS2_k127_7009700_29 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 306.0
TLS2_k127_7009700_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1089.0
TLS2_k127_7009700_30 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000163 268.0
TLS2_k127_7009700_31 PFAM Rhodanese domain protein K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008267 263.0
TLS2_k127_7009700_32 Protein conserved in bacteria K09939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003412 260.0
TLS2_k127_7009700_33 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000006993 245.0
TLS2_k127_7009700_34 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001347 236.0
TLS2_k127_7009700_35 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000000000001374 227.0
TLS2_k127_7009700_36 Domain of unknown function (DUF4920) - - - 0.00000000000000000000000000000000000000000000000000000000002304 212.0
TLS2_k127_7009700_37 Protein of unknown function (DUF2924) - - - 0.0000000000000000000000000000000000000000000000000000000029 205.0
TLS2_k127_7009700_38 - - - - 0.000000000000000000000000000000000000000000000000000002051 194.0
TLS2_k127_7009700_39 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000003712 183.0
TLS2_k127_7009700_4 Beta propeller domain - - - 2.993e-299 952.0
TLS2_k127_7009700_40 methyltransferase - - - 0.0000000000000000000000000000000000000000000001279 178.0
TLS2_k127_7009700_41 Domain of unknown function (DUF4336) - - - 0.000000000000000000000000000000000000000001767 166.0
TLS2_k127_7009700_42 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000002679 154.0
TLS2_k127_7009700_43 - - - - 0.000000000000000000000004429 102.0
TLS2_k127_7009700_44 - - - - 0.0000000000000000000001551 108.0
TLS2_k127_7009700_45 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000001329 104.0
TLS2_k127_7009700_46 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.000000000000000000003677 109.0
TLS2_k127_7009700_47 Protein of unknown function (DUF2933) - - - 0.00000000000000007291 82.0
TLS2_k127_7009700_48 YXWGXW repeat (2 copies) - - - 0.000000000000008462 87.0
TLS2_k127_7009700_49 - - - - 0.0000000000001675 72.0
TLS2_k127_7009700_5 AMP-binding enzyme - - - 8.611e-273 876.0
TLS2_k127_7009700_51 PFAM transposase IS3 IS911 family protein K07483 - - 0.000000000005184 71.0
TLS2_k127_7009700_52 - - - - 0.00000008698 55.0
TLS2_k127_7009700_53 - - - - 0.0000003092 61.0
TLS2_k127_7009700_54 PFAM IS66 Orf2 family protein K07484 - - 0.0000004024 52.0
TLS2_k127_7009700_55 Methyltransferase - - - 0.00001405 48.0
TLS2_k127_7009700_56 - - - - 0.0001541 48.0
TLS2_k127_7009700_57 PFAM Plasmid stabilisation system K19092 - - 0.0005155 46.0
TLS2_k127_7009700_6 - - - - 6.926e-259 822.0
TLS2_k127_7009700_7 Resolvase, N terminal domain K06400 - - 1.946e-252 787.0
TLS2_k127_7009700_8 SMART helicase c2 K03722 - 3.6.4.12 9.923e-245 771.0
TLS2_k127_7009700_9 Serine dehydratase beta chain K01752 - 4.3.1.17 1.796e-224 703.0
TLS2_k127_7021543_0 Tetratricopeptide repeat - - - 0.0 1429.0
TLS2_k127_7021543_1 ABC transporter K06147,K06148 - - 1.029e-311 964.0
TLS2_k127_7021543_10 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 498.0
TLS2_k127_7021543_11 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 473.0
TLS2_k127_7021543_12 CoA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 452.0
TLS2_k127_7021543_13 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 422.0
TLS2_k127_7021543_14 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 427.0
TLS2_k127_7021543_16 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 346.0
TLS2_k127_7021543_17 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 308.0
TLS2_k127_7021543_18 Peptidase M50B-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 295.0
TLS2_k127_7021543_19 Bacterial sugar transferase K13012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 287.0
TLS2_k127_7021543_2 protein involved in exopolysaccharide biosynthesis K16554 - - 1.689e-294 922.0
TLS2_k127_7021543_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004816 248.0
TLS2_k127_7021543_21 Cysteine desulfurase family protein, VC1184 subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001694 256.0
TLS2_k127_7021543_22 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000007055 224.0
TLS2_k127_7021543_23 oxidation-reduction process K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000006396 221.0
TLS2_k127_7021543_24 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000001413 188.0
TLS2_k127_7021543_25 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000002691 163.0
TLS2_k127_7021543_26 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000000000154 158.0
TLS2_k127_7021543_27 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000002369 145.0
TLS2_k127_7021543_28 Activator of Hsp90 ATPase - - - 0.00000000000000005967 87.0
TLS2_k127_7021543_29 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000004162 58.0
TLS2_k127_7021543_3 ATPase family associated with various cellular activities (AAA) - - - 5.858e-278 877.0
TLS2_k127_7021543_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 8.113e-221 710.0
TLS2_k127_7021543_5 Tetratricopeptide repeat - - - 4.143e-219 713.0
TLS2_k127_7021543_6 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 1.827e-207 663.0
TLS2_k127_7021543_7 O-antigen ligase like membrane protein K18814 - - 5.382e-200 649.0
TLS2_k127_7021543_8 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 523.0
TLS2_k127_7021543_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 533.0
TLS2_k127_7022100_0 Domain of unknown function (DUF3488) - - - 2.445e-260 848.0
TLS2_k127_7022100_1 Forkhead associated domain - - - 2.799e-253 785.0
TLS2_k127_7022100_10 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 587.0
TLS2_k127_7022100_11 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 571.0
TLS2_k127_7022100_12 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 542.0
TLS2_k127_7022100_13 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 530.0
TLS2_k127_7022100_14 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 526.0
TLS2_k127_7022100_15 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 522.0
TLS2_k127_7022100_16 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 512.0
TLS2_k127_7022100_17 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 506.0
TLS2_k127_7022100_18 Protein of unknown function (DUF1688) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 500.0
TLS2_k127_7022100_19 Belongs to the ompA family K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 482.0
TLS2_k127_7022100_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.206e-231 720.0
TLS2_k127_7022100_20 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 462.0
TLS2_k127_7022100_21 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 449.0
TLS2_k127_7022100_22 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 443.0
TLS2_k127_7022100_23 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 439.0
TLS2_k127_7022100_24 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 434.0
TLS2_k127_7022100_25 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 446.0
TLS2_k127_7022100_26 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 439.0
TLS2_k127_7022100_27 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 408.0
TLS2_k127_7022100_28 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 430.0
TLS2_k127_7022100_29 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 398.0
TLS2_k127_7022100_3 GTP cyclohydrolase N terminal - - - 2.66e-227 710.0
TLS2_k127_7022100_30 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008093 405.0
TLS2_k127_7022100_31 PfkB domain protein K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 361.0
TLS2_k127_7022100_32 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 363.0
TLS2_k127_7022100_33 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 362.0
TLS2_k127_7022100_34 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 342.0
TLS2_k127_7022100_35 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 349.0
TLS2_k127_7022100_36 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 340.0
TLS2_k127_7022100_37 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 306.0
TLS2_k127_7022100_38 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 290.0
TLS2_k127_7022100_39 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001017 282.0
TLS2_k127_7022100_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 6.413e-216 674.0
TLS2_k127_7022100_40 Bacterial regulatory proteins, tetR family K13770 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000127 282.0
TLS2_k127_7022100_41 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001657 278.0
TLS2_k127_7022100_42 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004509 278.0
TLS2_k127_7022100_43 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000179 276.0
TLS2_k127_7022100_44 Cell division protein FtsQ K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003027 257.0
TLS2_k127_7022100_45 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000001963 244.0
TLS2_k127_7022100_46 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000123 246.0
TLS2_k127_7022100_47 cell redox homeostasis K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000002132 218.0
TLS2_k127_7022100_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 3.738e-214 677.0
TLS2_k127_7022100_50 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000004219 179.0
TLS2_k127_7022100_51 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000005326 165.0
TLS2_k127_7022100_54 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000002829 130.0
TLS2_k127_7022100_55 protein-glutamate methylesterase activity K03412,K03413,K06597,K13924 - 2.1.1.80,3.1.1.61,3.5.1.44 0.0000000000000000000000000000001168 139.0
TLS2_k127_7022100_56 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000001436 106.0
TLS2_k127_7022100_57 iron ion homeostasis K04758 - - 0.000000000000000000000005537 103.0
TLS2_k127_7022100_59 exo-alpha-(2->6)-sialidase activity - - - 0.000005576 58.0
TLS2_k127_7022100_6 - - - - 2.527e-207 670.0
TLS2_k127_7022100_60 repeat-containing protein - - - 0.0000435 57.0
TLS2_k127_7022100_7 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.567e-207 653.0
TLS2_k127_7022100_8 protein kinase activity - - - 5.817e-205 668.0
TLS2_k127_7022100_9 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 617.0
TLS2_k127_7059452_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0 1204.0
TLS2_k127_7059452_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1125.0
TLS2_k127_7059452_10 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 500.0
TLS2_k127_7059452_11 Lipase maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 475.0
TLS2_k127_7059452_12 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 420.0
TLS2_k127_7059452_13 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 387.0
TLS2_k127_7059452_14 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 336.0
TLS2_k127_7059452_15 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 360.0
TLS2_k127_7059452_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 296.0
TLS2_k127_7059452_17 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003095 279.0
TLS2_k127_7059452_18 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004128 271.0
TLS2_k127_7059452_19 Protein conserved in bacteria K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005404 245.0
TLS2_k127_7059452_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0 1122.0
TLS2_k127_7059452_20 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006815 258.0
TLS2_k127_7059452_22 - - - - 0.00000000000000000000000000000000000000000000000000001002 199.0
TLS2_k127_7059452_24 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000001774 115.0
TLS2_k127_7059452_25 Domain of unknown function (DUF3841) - - - 0.000000000000000000000004382 114.0
TLS2_k127_7059452_26 sodium:proton antiporter activity K06382 - 3.1.3.16 0.000000000004533 79.0
TLS2_k127_7059452_27 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000001627 75.0
TLS2_k127_7059452_28 - - - - 0.00006235 51.0
TLS2_k127_7059452_3 oligopeptide transporter, OPT family - - - 1.685e-294 914.0
TLS2_k127_7059452_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 1.862e-266 868.0
TLS2_k127_7059452_5 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 1.476e-241 752.0
TLS2_k127_7059452_6 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 2.058e-202 640.0
TLS2_k127_7059452_7 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 601.0
TLS2_k127_7059452_8 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 580.0
TLS2_k127_7059452_9 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 532.0
TLS2_k127_7067213_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1312.0
TLS2_k127_7067213_1 Bacterial DNA topoisomeraes I ATP-binding domain K03169 - 5.99.1.2 0.0 1089.0
TLS2_k127_7067213_10 transporter antisigma-factor antagonist STAS K17762 - - 0.0000000000000000000000000000000000000000000000003023 178.0
TLS2_k127_7067213_11 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.000000000000000000000000000000000000000000000005701 175.0
TLS2_k127_7067213_12 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000000000000000000000005728 121.0
TLS2_k127_7067213_13 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000000000000000000000000001151 113.0
TLS2_k127_7067213_2 Histidine kinase-like ATPase domain - - - 1.344e-238 757.0
TLS2_k127_7067213_3 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 456.0
TLS2_k127_7067213_4 STAS domain K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 355.0
TLS2_k127_7067213_5 PFAM Stage II sporulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 317.0
TLS2_k127_7067213_6 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 329.0
TLS2_k127_7067213_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001116 247.0
TLS2_k127_7067213_8 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000000000000003056 228.0
TLS2_k127_7067213_9 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000001402 228.0
TLS2_k127_7110541_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1586.0
TLS2_k127_7110541_1 PrkA serine protein kinase C-terminal domain - - - 0.0 1160.0
TLS2_k127_7110541_10 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 388.0
TLS2_k127_7110541_11 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000102 274.0
TLS2_k127_7110541_12 fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002241 244.0
TLS2_k127_7110541_13 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002648 243.0
TLS2_k127_7110541_2 Receptor K02014 - - 0.0 1126.0
TLS2_k127_7110541_3 Carboxypeptidase regulatory-like domain - - - 3.874e-229 737.0
TLS2_k127_7110541_4 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 600.0
TLS2_k127_7110541_5 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 531.0
TLS2_k127_7110541_7 lipid kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 441.0
TLS2_k127_7110541_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 439.0
TLS2_k127_7110541_9 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 365.0
TLS2_k127_7123801_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0 2038.0
TLS2_k127_7123801_1 CoA-substrate-specific enzyme activase - - - 0.0 1995.0
TLS2_k127_7123801_10 Histidine ammonia-lyase K01745 - 4.3.1.3 5.28e-236 758.0
TLS2_k127_7123801_11 imidazolonepropionase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 615.0
TLS2_k127_7123801_12 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K01115 - 3.1.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 564.0
TLS2_k127_7123801_13 AAA domain, putative AbiEii toxin, Type IV TA system K06926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 537.0
TLS2_k127_7123801_14 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 512.0
TLS2_k127_7123801_15 Peptidase inhibitor I9 K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 466.0
TLS2_k127_7123801_17 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 417.0
TLS2_k127_7123801_18 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 398.0
TLS2_k127_7123801_19 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 420.0
TLS2_k127_7123801_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1246.0
TLS2_k127_7123801_20 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 389.0
TLS2_k127_7123801_21 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 343.0
TLS2_k127_7123801_22 PFAM Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 349.0
TLS2_k127_7123801_23 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 316.0
TLS2_k127_7123801_24 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 304.0
TLS2_k127_7123801_28 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001196 264.0
TLS2_k127_7123801_29 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005764 254.0
TLS2_k127_7123801_3 Tetratricopeptide repeat - - - 0.0 1225.0
TLS2_k127_7123801_30 RNA pseudouridylate synthase K06175 - 5.4.99.26 0.000000000000000000000000000000000000000000000000000000000000000000004548 243.0
TLS2_k127_7123801_31 membrane K07148 - - 0.000000000000000000000000000000000000000000000000000000000000000000004804 257.0
TLS2_k127_7123801_32 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000000000000000000000000000003298 213.0
TLS2_k127_7123801_33 von Willebrand factor type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000006603 210.0
TLS2_k127_7123801_34 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000008353 190.0
TLS2_k127_7123801_35 RloB-like protein - - - 0.00000000000000000000000000000000000000000001483 174.0
TLS2_k127_7123801_37 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000008029 156.0
TLS2_k127_7123801_38 aminoglycoside - - - 0.00000000000000000000000000000000000001469 157.0
TLS2_k127_7123801_4 Tetratricopeptide repeat - - - 0.0 1214.0
TLS2_k127_7123801_40 domain protein - - - 0.0000000000000000000000001293 111.0
TLS2_k127_7123801_41 - - - - 0.0000000000000000000000003444 118.0
TLS2_k127_7123801_42 - - - - 0.000000000000000000002958 99.0
TLS2_k127_7123801_43 serine threonine protein kinase - - - 0.00000000000000000004442 108.0
TLS2_k127_7123801_44 - - - - 0.0000000000001196 83.0
TLS2_k127_7123801_45 Methyltransferase domain - - - 0.000000001686 68.0
TLS2_k127_7123801_46 Alternative locus ID - - - 0.000009105 56.0
TLS2_k127_7123801_47 Non-ribosomal peptide synthetase modules and related proteins K04780,K16432 - - 0.00007664 55.0
TLS2_k127_7123801_5 Periplasmic protein TonB links inner and outer membranes - - - 7.299e-291 912.0
TLS2_k127_7123801_6 4 iron, 4 sulfur cluster binding - - - 1.632e-284 885.0
TLS2_k127_7123801_7 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.016e-259 816.0
TLS2_k127_7123801_8 PFAM Protein kinase domain - - - 3.877e-259 858.0
TLS2_k127_7123801_9 Highly conserved protein containing a thioredoxin domain - - - 4.882e-237 756.0
TLS2_k127_7137229_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 608.0
TLS2_k127_7137229_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000003448 241.0
TLS2_k127_7137229_2 - - - - 0.00000000000000000000000000000002383 133.0
TLS2_k127_7137229_3 Tetratricopeptide repeats - - - 0.000000001594 59.0
TLS2_k127_717974_0 CARDB - - - 3.866e-310 990.0
TLS2_k127_717974_1 Sulfatase - - - 1.139e-308 974.0
TLS2_k127_717974_2 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 601.0
TLS2_k127_717974_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008146 278.0
TLS2_k127_717974_4 PrcB C-terminal - - - 0.0004876 49.0
TLS2_k127_7182131_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 9.511e-300 929.0
TLS2_k127_7182131_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 639.0
TLS2_k127_7182131_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 599.0
TLS2_k127_7182131_3 DNA-binding response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 512.0
TLS2_k127_7182131_4 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000001485 221.0
TLS2_k127_7182131_7 - - - - 0.00001045 51.0
TLS2_k127_7185444_0 Zn-dependent proteases and their inactivated homologs K03592 - - 1.667e-230 728.0
TLS2_k127_7185444_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 533.0
TLS2_k127_7185444_11 protein conserved in cyanobacteria - - - 0.00000973 57.0
TLS2_k127_7185444_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 454.0
TLS2_k127_7185444_4 BMC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 341.0
TLS2_k127_7185444_5 guanyl-nucleotide exchange factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 293.0
TLS2_k127_7185444_6 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007178 245.0
TLS2_k127_7185444_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000002167 223.0
TLS2_k127_7185444_8 Fic/DOC family K07341 - - 0.0000000000000000000000000000000000000000007695 160.0
TLS2_k127_7185444_9 PFAM SpoVT AbrB K07172,K18842 - - 0.000000000000000000000008283 104.0
TLS2_k127_7390288_0 Histidine kinase - - - 0.0 1613.0
TLS2_k127_7390288_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1301.0
TLS2_k127_7390288_10 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 507.0
TLS2_k127_7390288_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 507.0
TLS2_k127_7390288_12 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 503.0
TLS2_k127_7390288_13 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 488.0
TLS2_k127_7390288_14 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 480.0
TLS2_k127_7390288_15 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 432.0
TLS2_k127_7390288_16 Sulfatase-modifying factor enzyme 1 K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 406.0
TLS2_k127_7390288_17 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 403.0
TLS2_k127_7390288_18 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 325.0
TLS2_k127_7390288_19 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 312.0
TLS2_k127_7390288_2 RecQ zinc-binding K03654 - 3.6.4.12 3.108e-301 938.0
TLS2_k127_7390288_20 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 307.0
TLS2_k127_7390288_21 Uracil DNA glycosylase superfamily K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 288.0
TLS2_k127_7390288_22 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005229 302.0
TLS2_k127_7390288_23 acetyltransferases and hydrolases with the alpha beta hydrolase fold K00650 - 2.3.1.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000001441 282.0
TLS2_k127_7390288_26 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000009229 243.0
TLS2_k127_7390288_27 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001103 234.0
TLS2_k127_7390288_28 FHA domain - - - 0.000000000000000000000000000000000000000000000000000000000000003101 229.0
TLS2_k127_7390288_29 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000005154 223.0
TLS2_k127_7390288_3 Sulfatase-modifying factor enzyme 1 - - - 1.471e-264 839.0
TLS2_k127_7390288_31 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000002351 231.0
TLS2_k127_7390288_32 NAT, N-acetyltransferase, of N-acetylglutamate synthase K22478 - 2.3.1.1,2.7.2.8 0.00000000000000000000000000000000000000000000000000001409 213.0
TLS2_k127_7390288_33 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000006889 171.0
TLS2_k127_7390288_34 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.0000000000000000000000000000000000008225 156.0
TLS2_k127_7390288_35 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000002414 139.0
TLS2_k127_7390288_38 guanyl-nucleotide exchange factor activity K02034 - - 0.00000000000001139 88.0
TLS2_k127_7390288_4 ABC transporter K06147,K18889 - - 2.695e-261 817.0
TLS2_k127_7390288_5 ABC transporter transmembrane region K06147,K18890 - - 3.969e-253 822.0
TLS2_k127_7390288_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 6.814e-227 707.0
TLS2_k127_7390288_7 Transcriptional regulator, Fis family - - - 8.398e-201 638.0
TLS2_k127_7390288_8 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 593.0
TLS2_k127_7390288_9 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 532.0
TLS2_k127_7407630_0 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 1.578e-209 661.0
TLS2_k127_7407630_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 591.0
TLS2_k127_7407630_11 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000235 245.0
TLS2_k127_7407630_12 membrane organization K07277 - - 0.000000000000000000000000000000000000000000000000000000000000001428 238.0
TLS2_k127_7407630_13 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000001007 225.0
TLS2_k127_7407630_14 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000158 131.0
TLS2_k127_7407630_15 Transposase K07483 - - 0.00000000000000005009 87.0
TLS2_k127_7407630_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000003967 82.0
TLS2_k127_7407630_17 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.000000002541 69.0
TLS2_k127_7407630_18 COG0456 Acetyltransferases - - - 0.000000005107 66.0
TLS2_k127_7407630_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 462.0
TLS2_k127_7407630_3 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 454.0
TLS2_k127_7407630_4 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 400.0
TLS2_k127_7407630_5 HTH-like domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 359.0
TLS2_k127_7407630_6 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 340.0
TLS2_k127_7407630_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 337.0
TLS2_k127_7407630_8 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 322.0
TLS2_k127_7407630_9 Putative exonuclease SbcCD, C subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 316.0
TLS2_k127_800878_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2496.0
TLS2_k127_800878_1 WD40-like Beta Propeller Repeat - - - 0.0 1299.0
TLS2_k127_800878_10 domain, Protein - - - 4.888e-211 669.0
TLS2_k127_800878_11 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 575.0
TLS2_k127_800878_12 Phenylacetate-CoA oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 484.0
TLS2_k127_800878_13 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 452.0
TLS2_k127_800878_14 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 453.0
TLS2_k127_800878_15 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 434.0
TLS2_k127_800878_16 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 402.0
TLS2_k127_800878_17 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 392.0
TLS2_k127_800878_18 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 369.0
TLS2_k127_800878_2 Two component regulator propeller - - - 3.99e-277 869.0
TLS2_k127_800878_20 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 349.0
TLS2_k127_800878_21 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 304.0
TLS2_k127_800878_22 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 285.0
TLS2_k127_800878_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004063 263.0
TLS2_k127_800878_26 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000397 250.0
TLS2_k127_800878_27 translation release factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000001057 237.0
TLS2_k127_800878_28 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001624 232.0
TLS2_k127_800878_3 Membrane - - - 5.101e-273 856.0
TLS2_k127_800878_30 SMART metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000003909 183.0
TLS2_k127_800878_31 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000007593 194.0
TLS2_k127_800878_32 Biotin-requiring enzyme - - - 0.0000000000000000000000000000000000000000000004376 189.0
TLS2_k127_800878_35 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000000000000000000000000000000000000003049 171.0
TLS2_k127_800878_36 curli production assembly transport component CsgG - - - 0.00000000000000000000000000000000000000000001334 172.0
TLS2_k127_800878_37 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000009626 160.0
TLS2_k127_800878_39 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000000000000000121 156.0
TLS2_k127_800878_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 7.74e-251 803.0
TLS2_k127_800878_40 Zn peptidase - - - 0.0000000000000000000000000000000000002701 155.0
TLS2_k127_800878_41 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.00000000000000000000000000000000008864 134.0
TLS2_k127_800878_42 PilZ domain - - - 0.0000000000000000000000000000000212 131.0
TLS2_k127_800878_43 Cytochrome c - - - 0.00000000000000000000000000002185 123.0
TLS2_k127_800878_44 - - - - 0.00000000000000000000000000004476 125.0
TLS2_k127_800878_45 - - - - 0.0000000000000000000141 96.0
TLS2_k127_800878_46 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000001297 84.0
TLS2_k127_800878_47 Redoxin K03564 - 1.11.1.15 0.000000000000000138 82.0
TLS2_k127_800878_48 COG3209 Rhs family protein - - - 0.0000000000000006543 93.0
TLS2_k127_800878_49 Band 7 protein K07192 - - 0.000000004395 70.0
TLS2_k127_800878_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.18e-243 762.0
TLS2_k127_800878_51 protein secretion by the type VII secretion system - - - 0.00005948 56.0
TLS2_k127_800878_6 Calcineurin-like phosphoesterase superfamily domain - - - 8.307e-241 757.0
TLS2_k127_800878_7 DNA internalization-related competence protein ComEC Rec2 K02238 - - 6.012e-225 727.0
TLS2_k127_800878_8 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 2.207e-218 734.0
TLS2_k127_800878_9 Trypsin - - - 6.179e-217 681.0
TLS2_k127_858160_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 6.248e-241 764.0
TLS2_k127_858160_1 serine threonine protein kinase K12132 - 2.7.11.1 8.301e-239 765.0
TLS2_k127_858160_10 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000002165 223.0
TLS2_k127_858160_11 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000000004313 204.0
TLS2_k127_858160_12 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000004607 123.0
TLS2_k127_858160_14 Tetratrico peptide repeat - - - 0.00000000000000003058 89.0
TLS2_k127_858160_15 DNA integration - - - 0.00000000001424 68.0
TLS2_k127_858160_16 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00001089 55.0
TLS2_k127_858160_2 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 1.505e-229 718.0
TLS2_k127_858160_3 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 497.0
TLS2_k127_858160_4 desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 464.0
TLS2_k127_858160_5 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 359.0
TLS2_k127_858160_6 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 355.0
TLS2_k127_858160_7 SMART Integrin alpha beta-propellor repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 340.0
TLS2_k127_858160_8 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002748 259.0
TLS2_k127_858160_9 Rieske [2Fe-2S] domain K15762 - - 0.00000000000000000000000000000000000000000000000000000000000002146 237.0
TLS2_k127_85840_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.0 1239.0
TLS2_k127_85840_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.284e-302 950.0
TLS2_k127_85840_10 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 392.0
TLS2_k127_85840_11 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 351.0
TLS2_k127_85840_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 348.0
TLS2_k127_85840_13 cobalamin binding K03496,K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 340.0
TLS2_k127_85840_14 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 350.0
TLS2_k127_85840_15 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 351.0
TLS2_k127_85840_16 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 342.0
TLS2_k127_85840_17 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 334.0
TLS2_k127_85840_18 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 321.0
TLS2_k127_85840_19 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 309.0
TLS2_k127_85840_2 DNA helicase K03657 - 3.6.4.12 4.818e-301 941.0
TLS2_k127_85840_20 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 301.0
TLS2_k127_85840_21 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002546 306.0
TLS2_k127_85840_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001739 258.0
TLS2_k127_85840_23 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000001984 200.0
TLS2_k127_85840_24 - - - - 0.0000000000000000000000000000000000000000000000000000001975 203.0
TLS2_k127_85840_25 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000000001076 155.0
TLS2_k127_85840_26 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000004294 161.0
TLS2_k127_85840_28 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000000000002539 144.0
TLS2_k127_85840_29 protein kinase activity - - - 0.00000000000000000000000002227 124.0
TLS2_k127_85840_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 9.552e-282 880.0
TLS2_k127_85840_31 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00360,K02192 - - 0.0000000000000000000003454 98.0
TLS2_k127_85840_32 self proteolysis K07004 - - 0.00000000000000000004929 98.0
TLS2_k127_85840_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.648e-244 771.0
TLS2_k127_85840_5 PFAM TrkA-N domain protein K03499 - - 9.891e-228 711.0
TLS2_k127_85840_6 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 6.608e-215 701.0
TLS2_k127_85840_7 Sodium:dicarboxylate symporter family - - - 6.299e-205 647.0
TLS2_k127_85840_8 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 608.0
TLS2_k127_85840_9 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 554.0
TLS2_k127_87028_0 polyketide synthase - - - 0.0 2305.0
TLS2_k127_87028_1 Enoylreductase K12436,K15643,K16396,K16397 - - 0.0 2280.0
TLS2_k127_87028_10 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 592.0
TLS2_k127_87028_11 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 546.0
TLS2_k127_87028_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 540.0
TLS2_k127_87028_13 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 538.0
TLS2_k127_87028_14 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 505.0
TLS2_k127_87028_15 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 449.0
TLS2_k127_87028_16 belongs to the thioredoxin family K00384,K02453,K11912,K20543 - 1.8.1.9,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 444.0
TLS2_k127_87028_17 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 410.0
TLS2_k127_87028_18 Rhodopirellula transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 411.0
TLS2_k127_87028_19 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 371.0
TLS2_k127_87028_2 PKS_KR - - - 0.0 2083.0
TLS2_k127_87028_20 SMART Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 306.0
TLS2_k127_87028_21 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002843 293.0
TLS2_k127_87028_22 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002928 279.0
TLS2_k127_87028_23 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000988 292.0
TLS2_k127_87028_24 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003965 287.0
TLS2_k127_87028_25 thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005261 264.0
TLS2_k127_87028_26 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005071 241.0
TLS2_k127_87028_27 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000000000000000000000000000000003568 196.0
TLS2_k127_87028_28 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000224 186.0
TLS2_k127_87028_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1187.0
TLS2_k127_87028_30 FcoT-like thioesterase domain - - - 0.000000000000000000000000000000000000001363 156.0
TLS2_k127_87028_31 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000002552 151.0
TLS2_k127_87028_32 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000004679 153.0
TLS2_k127_87028_33 Transposase - - - 0.000000000000000000232 91.0
TLS2_k127_87028_35 Putative zinc- or iron-chelating domain - - - 0.0000000000004024 83.0
TLS2_k127_87028_36 - - - - 0.00000000009229 64.0
TLS2_k127_87028_37 synthase - - - 0.000002355 56.0
TLS2_k127_87028_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 4.425e-268 834.0
TLS2_k127_87028_5 Domain of unknown function (DUF362) - - - 8.279e-263 818.0
TLS2_k127_87028_6 AMP-binding enzyme K01897 - 6.2.1.3 8.228e-251 787.0
TLS2_k127_87028_7 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.864e-234 731.0
TLS2_k127_87028_8 AMP-binding enzyme C-terminal domain K00666 - - 1.859e-216 683.0
TLS2_k127_87028_9 ABC-type transport system involved in lipoprotein release permease component K09808 - - 8.727e-210 704.0
TLS2_k127_890377_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 1.951e-211 680.0
TLS2_k127_890377_1 conserved protein (DUF2183) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 494.0
TLS2_k127_890377_11 - - - - 0.00000000000000000000000000000004863 128.0
TLS2_k127_890377_12 methylamine metabolic process K15977 - - 0.0000000000000000000000000001714 123.0
TLS2_k127_890377_14 terpene synthase activity K18111 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006714,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0010333,GO:0010334,GO:0016106,GO:0016114,GO:0016787,GO:0016822,GO:0016823,GO:0016829,GO:0016835,GO:0016838,GO:0030145,GO:0042214,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046246,GO:0046872,GO:0046914,GO:0051761,GO:0051762,GO:0071704,GO:1901576 4.2.1.138,4.2.3.89 0.00000008706 64.0
TLS2_k127_890377_15 - - - - 0.00005279 54.0
TLS2_k127_890377_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 491.0
TLS2_k127_890377_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 482.0
TLS2_k127_890377_5 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 424.0
TLS2_k127_890377_6 transmembrane signaling receptor activity K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 371.0
TLS2_k127_890377_7 abc transporter atp-binding protein K10038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 377.0
TLS2_k127_890377_8 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 291.0
TLS2_k127_890377_9 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000004688 209.0
TLS2_k127_967466_0 Diguanylate cyclase - - - 0.0 1115.0
TLS2_k127_967466_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 1.754e-243 769.0
TLS2_k127_967466_10 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 394.0
TLS2_k127_967466_11 BMC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 349.0
TLS2_k127_967466_12 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 316.0
TLS2_k127_967466_13 Enoyl-CoA hydratase carnithine racemase K01692,K11264 - 4.1.1.41,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000005285 254.0
TLS2_k127_967466_14 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001582 273.0
TLS2_k127_967466_15 BMC - - - 0.0000000000000000000000000000000000000000000000000000000000000000004709 249.0
TLS2_k127_967466_16 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000006349 178.0
TLS2_k127_967466_17 BMC K04027 - - 0.00000000000000000000000000000000000000000000001004 173.0
TLS2_k127_967466_18 KR domain K07124 - - 0.0000000000000000000000000000000000000000006134 177.0
TLS2_k127_967466_19 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000000000000000000000002489 162.0
TLS2_k127_967466_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 3.432e-242 765.0
TLS2_k127_967466_20 bacterial-type flagellum organization K02411 - - 0.000000000000000000000000000000000000002279 164.0
TLS2_k127_967466_21 bacterial-type flagellum organization - - - 0.0000000000000000000000000000000000185 147.0
TLS2_k127_967466_22 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000006465 115.0
TLS2_k127_967466_23 cell cycle K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000000000000000001539 113.0
TLS2_k127_967466_27 Nucleoside H+ symporter K05820 - - 0.000000000000000004571 97.0
TLS2_k127_967466_3 Aldehyde dehydrogenase family K04021 - - 2.899e-241 752.0
TLS2_k127_967466_30 - - - - 0.00006026 50.0
TLS2_k127_967466_4 - - - - 6.383e-206 660.0
TLS2_k127_967466_5 Large family of predicted nucleotide-binding domains K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 550.0
TLS2_k127_967466_7 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 445.0
TLS2_k127_967466_9 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 395.0
TLS2_k127_980952_0 AAA ATPase domain - - - 0.0 1521.0
TLS2_k127_980952_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1468.0
TLS2_k127_980952_10 Predicted AAA-ATPase - - - 1.02e-246 773.0
TLS2_k127_980952_11 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 6.011e-218 682.0
TLS2_k127_980952_12 Belongs to the aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 7.1e-210 668.0
TLS2_k127_980952_13 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 581.0
TLS2_k127_980952_14 self proteolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 547.0
TLS2_k127_980952_15 Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 529.0
TLS2_k127_980952_16 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 526.0
TLS2_k127_980952_17 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 430.0
TLS2_k127_980952_18 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 434.0
TLS2_k127_980952_19 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 426.0
TLS2_k127_980952_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0 1273.0
TLS2_k127_980952_20 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 389.0
TLS2_k127_980952_21 Dehydrogenase K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 412.0
TLS2_k127_980952_22 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 367.0
TLS2_k127_980952_23 Multicopper K04753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 359.0
TLS2_k127_980952_24 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 366.0
TLS2_k127_980952_25 1-Cys peroxiredoxin K11188 - 1.11.1.15,1.11.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 333.0
TLS2_k127_980952_26 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 336.0
TLS2_k127_980952_27 photoreceptor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002354 312.0
TLS2_k127_980952_28 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001971 275.0
TLS2_k127_980952_29 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000247 271.0
TLS2_k127_980952_3 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1221.0
TLS2_k127_980952_30 - K12541 - - 0.00000000000000000000000000000000000000000000000000000000000000000003579 239.0
TLS2_k127_980952_31 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005892 235.0
TLS2_k127_980952_33 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000000000000000000000000000000000000000489 258.0
TLS2_k127_980952_34 Putative transposase, YhgA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000002057 230.0
TLS2_k127_980952_35 HEPN domain - - - 0.00000000000000000000000000000000000000000000000000000000000001919 227.0
TLS2_k127_980952_36 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000008602 217.0
TLS2_k127_980952_37 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000002149 235.0
TLS2_k127_980952_38 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000000000000000000000000000000000000000000000000000007811 203.0
TLS2_k127_980952_39 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000008007 200.0
TLS2_k127_980952_4 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1202.0
TLS2_k127_980952_40 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000001958 190.0
TLS2_k127_980952_41 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000002458 187.0
TLS2_k127_980952_42 Restriction K01153 - 3.1.21.3 0.00000000000000000000000000000000000000000000123 177.0
TLS2_k127_980952_43 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000000000000000000000000000009893 159.0
TLS2_k127_980952_44 Type I restriction modification DNA specificity domain - - - 0.0000000000000000000000000000000000000004575 153.0
TLS2_k127_980952_45 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases K01153 - 3.1.21.3 0.000000000000000000000000000000000000002803 154.0
TLS2_k127_980952_46 - - - - 0.00000000000000000000000000000000000000521 167.0
TLS2_k127_980952_48 - - - - 0.000000000000000000000000003082 118.0
TLS2_k127_980952_49 protein-disulfide reductase activity - - - 0.00000000000000000000000003605 123.0
TLS2_k127_980952_5 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 5.761e-314 999.0
TLS2_k127_980952_50 protein conserved in bacteria K09973 - - 0.0000000000000000000001965 114.0
TLS2_k127_980952_51 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.0000000000000000003958 89.0
TLS2_k127_980952_52 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.0000000000000000006163 99.0
TLS2_k127_980952_53 Domain of unknown function (DUF378) K09779 - - 0.00000000000000002355 84.0
TLS2_k127_980952_54 EF-hand, calcium binding motif - - - 0.0000000000000005189 87.0
TLS2_k127_980952_55 Bacterial Ig-like domain 2 - - - 0.00000000000001532 87.0
TLS2_k127_980952_56 AAA ATPase domain - - - 0.00000000000008166 80.0
TLS2_k127_980952_57 - - - - 0.0000000000007132 74.0
TLS2_k127_980952_58 PFAM CBS domain containing protein K07182 - - 0.000000004981 69.0
TLS2_k127_980952_59 polyketide synthase - - - 0.00000001082 68.0
TLS2_k127_980952_6 His Kinase A (phosphoacceptor) domain - - - 5.978e-293 929.0
TLS2_k127_980952_60 - - - - 0.00000004686 63.0
TLS2_k127_980952_61 PAAR motif - - - 0.00006319 49.0
TLS2_k127_980952_62 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.0003881 44.0
TLS2_k127_980952_7 Heat shock 70 kDa protein K04043 - - 9.463e-271 841.0
TLS2_k127_980952_8 HEAT repeats - - - 4.448e-266 831.0
TLS2_k127_980952_9 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 4.193e-252 788.0
TLS2_k127_985868_0 NUBPL iron-transfer P-loop NTPase K04562 - - 7.708e-214 675.0
TLS2_k127_985868_1 SIR2-like domain - - - 1.954e-200 697.0
TLS2_k127_985868_10 Domain of unknown function (DUF4180) - - - 0.00000000000000000000000000001317 122.0
TLS2_k127_985868_11 - - - - 0.00000000000002372 81.0
TLS2_k127_985868_12 Histidine kinase K13598 - 2.7.13.3 0.000000000005418 66.0
TLS2_k127_985868_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 477.0
TLS2_k127_985868_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 444.0
TLS2_k127_985868_4 transposase or invertase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 297.0
TLS2_k127_985868_5 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000003896 194.0
TLS2_k127_985868_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000005325 175.0
TLS2_k127_985868_7 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000001109 188.0
TLS2_k127_985868_8 - - - - 0.000000000000000000000000000000000000000001089 164.0
TLS2_k127_985868_9 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000002198 147.0