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Overview

ID MAG03994
Name TLS2_bin.27
Sample SMP0104
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Bryobacterales
Family Bryobacteraceae
Genus
Species
Assembly information
Completeness (%) 90.4
Contamination (%) 0.85
GC content (%) 66.0
N50 (bp) 16,088
Genome size (bp) 7,079,848

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes5580

Gene name Description KEGG GOs EC E-value Score Sequence
TLS2_k127_1014158_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 2.116e-225 723.0
TLS2_k127_1014158_1 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 531.0
TLS2_k127_1014158_10 Trehalose utilisation K09992 - - 0.000001571 55.0
TLS2_k127_1014158_2 COG0553 Superfamily II DNA RNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001141 282.0
TLS2_k127_1014158_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000112 264.0
TLS2_k127_1014158_4 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000324 181.0
TLS2_k127_1014158_5 - - - - 0.0000000000000000000000000000000000008794 156.0
TLS2_k127_1014158_6 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000001433 141.0
TLS2_k127_1014158_7 HEAT repeats - - - 0.00000000000000000000000000000008714 137.0
TLS2_k127_1014158_8 cyclopropane-fatty-acyl-phospholipid synthase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000009976 114.0
TLS2_k127_1014158_9 tail sheath protein - - - 0.000000000000008687 86.0
TLS2_k127_1018530_0 Carboxypeptidase regulatory-like domain - - - 0.0 1425.0
TLS2_k127_1018530_1 Cytochrome c - - - 1.592e-235 769.0
TLS2_k127_1018530_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 331.0
TLS2_k127_1018530_11 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 327.0
TLS2_k127_1018530_12 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002931 275.0
TLS2_k127_1018530_13 Protein of unknown function (DUF2490) - - - 0.000000000000000000000000000000000000000000000000000002349 200.0
TLS2_k127_1018530_14 COG0454 Histone acetyltransferase HPA2 and related - - - 0.00000000000000000000000000000000000000000000000000000373 206.0
TLS2_k127_1018530_15 - - - - 0.0000000000000000000000000000000000000000000000001452 179.0
TLS2_k127_1018530_16 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000004637 145.0
TLS2_k127_1018530_17 - - - - 0.0000000000000000000000000000000005713 136.0
TLS2_k127_1018530_18 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000004881 116.0
TLS2_k127_1018530_2 Protein of unknown function (DUF1501) - - - 4.846e-225 705.0
TLS2_k127_1018530_3 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K07443 - - 2.245e-222 712.0
TLS2_k127_1018530_4 Ribonuclease, Rne Rng family K08301 - - 3.055e-205 662.0
TLS2_k127_1018530_5 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 614.0
TLS2_k127_1018530_6 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 571.0
TLS2_k127_1018530_7 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 471.0
TLS2_k127_1018530_8 COG0454 Histone acetyltransferase HPA2 and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 389.0
TLS2_k127_1018530_9 Phosphomethylpyrimidine kinase K00882 - 2.7.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 370.0
TLS2_k127_1033152_0 PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 468.0
TLS2_k127_1033152_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 451.0
TLS2_k127_1033152_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 317.0
TLS2_k127_1033152_3 Glycogen debranching enzyme N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000005989 216.0
TLS2_k127_1047010_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 498.0
TLS2_k127_1047010_1 Nacht domain - - - 0.0000003161 54.0
TLS2_k127_1055286_0 siderophore transport K02014 - - 3.11e-299 955.0
TLS2_k127_1055286_1 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 565.0
TLS2_k127_1055286_2 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000001324 224.0
TLS2_k127_1055286_3 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000006397 132.0
TLS2_k127_1055286_4 Transposase zinc-ribbon domain - - - 0.0000000000000000000000005058 106.0
TLS2_k127_1059837_0 Carboxypeptidase regulatory-like domain - - - 2.769e-310 985.0
TLS2_k127_1059837_1 BNR repeat-containing family member - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 454.0
TLS2_k127_1059837_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 426.0
TLS2_k127_1059837_3 RESPONSE REGULATOR receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000001748 245.0
TLS2_k127_106257_0 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 566.0
TLS2_k127_106257_1 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000191 281.0
TLS2_k127_106257_2 - - - - 0.000000000000000000000000000000002062 132.0
TLS2_k127_106257_3 InterPro IPR007367 - - - 0.0000000000000000000000000005583 115.0
TLS2_k127_106257_4 Hydrogenase maturation protease - - - 0.000000000000001797 88.0
TLS2_k127_1077938_0 BNR repeat-like domain K05989 - 3.2.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 635.0
TLS2_k127_1077938_1 carboxylic acid catabolic process K12661 - 4.2.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005407 286.0
TLS2_k127_1077938_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0001326 51.0
TLS2_k127_1082473_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 532.0
TLS2_k127_1082473_1 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000000000000000000000000000000000000000000000000000000000000000008415 241.0
TLS2_k127_1082473_2 Protein of unknown function DUF86 - - - 0.0000000000000000001033 93.0
TLS2_k127_1084820_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009022 617.0
TLS2_k127_1084820_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 558.0
TLS2_k127_1084820_2 Neuraminidase (sialidase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 406.0
TLS2_k127_1084820_3 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001067 236.0
TLS2_k127_1085772_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 498.0
TLS2_k127_1085772_1 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 385.0
TLS2_k127_1085772_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 361.0
TLS2_k127_1085772_3 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009177 286.0
TLS2_k127_1085772_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000005776 220.0
TLS2_k127_1085772_5 formate dehydrogenase K03620 - - 0.000000000003708 74.0
TLS2_k127_1085772_6 Domain of unknown function (DUF4338) - - - 0.00001425 47.0
TLS2_k127_1087387_0 PFAM carbohydrate kinase K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 597.0
TLS2_k127_1087387_1 PFAM Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 370.0
TLS2_k127_1087387_10 Penicillinase repressor - - - 0.000000000000000000000000000000000004431 140.0
TLS2_k127_1087387_11 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000006071 107.0
TLS2_k127_1087387_12 - - - - 0.000000000000000004523 91.0
TLS2_k127_1087387_13 - - - - 0.0000000000000004826 89.0
TLS2_k127_1087387_14 Domain of unknown function (DUF4440) - - - 0.000001696 52.0
TLS2_k127_1087387_2 Domain of unknown function (DUF5060) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 359.0
TLS2_k127_1087387_3 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 329.0
TLS2_k127_1087387_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002917 269.0
TLS2_k127_1087387_5 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001353 261.0
TLS2_k127_1087387_6 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000004572 245.0
TLS2_k127_1087387_7 Aminotransferase class-III K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000007104 207.0
TLS2_k127_1087387_8 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000002682 190.0
TLS2_k127_1087387_9 - - - - 0.00000000000000000000000000000000000000005476 173.0
TLS2_k127_1109050_0 ImcF-related N-terminal domain K11891 - - 1.037e-285 915.0
TLS2_k127_1109050_1 ABC transporter, transmembrane K18890 - - 1.886e-255 801.0
TLS2_k127_1109050_10 COG COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 373.0
TLS2_k127_1109050_11 amine dehydrogenase activity K12287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 304.0
TLS2_k127_1109050_12 response to copper ion K01187,K16915 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 287.0
TLS2_k127_1109050_13 DNA alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005191 268.0
TLS2_k127_1109050_14 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001444 254.0
TLS2_k127_1109050_15 Type VI secretion system protein DotU K11892 - - 0.00000000000000000000000000000000000000000000000000000000008519 213.0
TLS2_k127_1109050_16 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000002706 214.0
TLS2_k127_1109050_17 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000005546 206.0
TLS2_k127_1109050_18 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000003654 204.0
TLS2_k127_1109050_19 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000009142 186.0
TLS2_k127_1109050_2 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 546.0
TLS2_k127_1109050_20 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000001519 169.0
TLS2_k127_1109050_21 iron ion homeostasis - - - 0.000000000000000000000000000000000000004654 158.0
TLS2_k127_1109050_22 DinB family - - - 0.000000000000000000000000000000000000008724 150.0
TLS2_k127_1109050_24 - - - - 0.000000000000000000000000000248 119.0
TLS2_k127_1109050_25 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000003903 115.0
TLS2_k127_1109050_3 carboxylic acid catabolic process K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 539.0
TLS2_k127_1109050_4 carboxylic acid catabolic process K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 529.0
TLS2_k127_1109050_5 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 511.0
TLS2_k127_1109050_6 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 500.0
TLS2_k127_1109050_7 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 492.0
TLS2_k127_1109050_8 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 441.0
TLS2_k127_1109050_9 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 389.0
TLS2_k127_1113962_0 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 7.026e-289 903.0
TLS2_k127_1113962_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 424.0
TLS2_k127_1113962_2 Belongs to the PdxA family K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000006379 269.0
TLS2_k127_1129903_0 PFAM aminotransferase, class I K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 601.0
TLS2_k127_1129903_1 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 496.0
TLS2_k127_1129903_2 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 451.0
TLS2_k127_1129903_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 420.0
TLS2_k127_1129903_4 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000008712 188.0
TLS2_k127_1129903_5 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000003494 156.0
TLS2_k127_1129903_6 domain, Protein K03112 - - 0.00000000000000000000000000000000008279 147.0
TLS2_k127_1129903_7 tagaturonate epimerase K21619 - 5.1.2.7 0.0000000000000000000000138 117.0
TLS2_k127_1129903_8 GYD domain - - - 0.00000000000000000001275 94.0
TLS2_k127_1178950_0 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 338.0
TLS2_k127_1178950_1 Chaperone - - - 0.000000000000001259 87.0
TLS2_k127_1178950_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000007268 62.0
TLS2_k127_1179704_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001086 274.0
TLS2_k127_1179704_1 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000005081 181.0
TLS2_k127_1179704_2 shape-determining protein MreD K03571 - - 0.00000000000000000000000004619 113.0
TLS2_k127_1180611_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 577.0
TLS2_k127_1180611_1 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 377.0
TLS2_k127_1180611_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 342.0
TLS2_k127_1180611_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 331.0
TLS2_k127_1180611_4 KAP family P-loop domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 321.0
TLS2_k127_1181118_0 Cytochrome c, class I - - - 7.117e-239 754.0
TLS2_k127_1181118_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 462.0
TLS2_k127_1181118_2 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 365.0
TLS2_k127_1181118_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002385 232.0
TLS2_k127_1184686_0 Transglutaminase/protease-like homologues - - - 0.0 1566.0
TLS2_k127_1184686_1 Circularly permuted ATP-grasp type 2 - - - 2.097e-251 801.0
TLS2_k127_1184686_10 GTP binding - - - 0.00003538 47.0
TLS2_k127_1184686_2 Circularly permuted ATP-grasp type 2 - - - 2.297e-224 704.0
TLS2_k127_1184686_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 463.0
TLS2_k127_1184686_4 PFAM Bacterial domain of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 372.0
TLS2_k127_1184686_5 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000003404 216.0
TLS2_k127_1184686_6 Type IV leader peptidase family K02278 - 3.4.23.43 0.0000000000000000000000000000000000000006868 155.0
TLS2_k127_1184686_7 F-box LRR-repeat protein - - - 0.000000000000000000000000000000000000001094 168.0
TLS2_k127_1184686_8 regulation of response to stimulus - - - 0.0000000000000000000000000000000613 139.0
TLS2_k127_11847_0 Protein of unknown function (DUF1587) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 347.0
TLS2_k127_11847_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 310.0
TLS2_k127_11847_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002079 239.0
TLS2_k127_11847_3 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000001734 174.0
TLS2_k127_11847_4 Leucine Rich repeat - - - 0.00000000000000000000000000000000000003365 166.0
TLS2_k127_11847_5 F-box and leucine-rich repeat protein 14 K10280 GO:0000151,GO:0000209,GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016567,GO:0016740,GO:0019005,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0031146,GO:0031461,GO:0032446,GO:0032991,GO:0036211,GO:0043161,GO:0043170,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051603,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234 - 0.00000003639 65.0
TLS2_k127_1185269_0 L-lactate permease K03303 - - 9.949e-199 634.0
TLS2_k127_1185269_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 562.0
TLS2_k127_1185269_10 - - - - 0.0000000000000000345 91.0
TLS2_k127_1185269_11 Bacterial PH domain - - - 0.00000000000001828 80.0
TLS2_k127_1185269_12 Protein of unknown function (DUF433) - - - 0.00000001932 61.0
TLS2_k127_1185269_13 Domain of unknown function (DUF4388) - - - 0.0000006237 60.0
TLS2_k127_1185269_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 469.0
TLS2_k127_1185269_3 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000004919 201.0
TLS2_k127_1185269_4 Bacterial PH domain K08981 - - 0.00000000000000000000000000000000000000000006522 173.0
TLS2_k127_1185269_5 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000002837 154.0
TLS2_k127_1185269_7 Roadblock/LC7 domain K07131 - - 0.0000000000000000000000584 102.0
TLS2_k127_1185269_8 Bacterial PH domain - - - 0.000000000000000000002583 98.0
TLS2_k127_1185269_9 Roadblock/LC7 domain - - - 0.000000000000000001577 101.0
TLS2_k127_1228831_0 membrane organization K07277,K09800 - - 2.024e-269 900.0
TLS2_k127_124793_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
TLS2_k127_124793_1 helicase superfamily c-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000005071 213.0
TLS2_k127_124793_2 zinc ion binding - - - 0.000000000000000000000000000000000000000000006954 175.0
TLS2_k127_1253197_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 5.431e-272 847.0
TLS2_k127_1253197_1 symporter activity - - - 0.000000000008041 66.0
TLS2_k127_1279826_0 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 364.0
TLS2_k127_1279826_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 324.0
TLS2_k127_1279826_2 TIGRFAM glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 304.0
TLS2_k127_1279826_3 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000006278 239.0
TLS2_k127_1279826_5 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000816 145.0
TLS2_k127_1279826_6 Belongs to the UPF0145 family - - - 0.000000000000005973 79.0
TLS2_k127_1282021_0 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 385.0
TLS2_k127_1282021_1 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.00000000000000000000000008257 110.0
TLS2_k127_128393_0 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 533.0
TLS2_k127_128393_1 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 464.0
TLS2_k127_128393_2 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 349.0
TLS2_k127_128393_3 membrane K00389 - - 0.00000000000224 75.0
TLS2_k127_128393_4 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000002731 64.0
TLS2_k127_1285944_0 Carboxypeptidase regulatory-like domain - - - 0.0 1088.0
TLS2_k127_1285944_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 554.0
TLS2_k127_1285944_10 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000002021 249.0
TLS2_k127_1285944_11 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000002992 222.0
TLS2_k127_1285944_12 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000004654 223.0
TLS2_k127_1285944_13 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000002968 214.0
TLS2_k127_1285944_14 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000003552 143.0
TLS2_k127_1285944_15 - - - - 0.000000000000000000001373 105.0
TLS2_k127_1285944_16 Protein of unknown function (DUF1553) - - - 0.0000000000008578 71.0
TLS2_k127_1285944_17 - - - - 0.000000001022 68.0
TLS2_k127_1285944_18 Peptidase_C39 like family - - - 0.00000000247 66.0
TLS2_k127_1285944_2 PFAM HipA domain protein K07154 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 507.0
TLS2_k127_1285944_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 423.0
TLS2_k127_1285944_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 437.0
TLS2_k127_1285944_5 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 356.0
TLS2_k127_1285944_6 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 328.0
TLS2_k127_1285944_7 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 312.0
TLS2_k127_1285944_8 Belongs to the HpcH HpaI aldolase family K01630,K02510,K12660 - 4.1.2.20,4.1.2.52,4.1.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000001401 258.0
TLS2_k127_1305608_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 6.503e-207 649.0
TLS2_k127_1305608_1 3-demethylubiquinone-9 3-O-methyltransferase activity K07011,K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 607.0
TLS2_k127_1305608_10 Methyltransferase domain - - - 0.000000000000000001514 99.0
TLS2_k127_1305608_11 Mannose-6-phosphate isomerase K01485 - 3.5.4.1 0.000000002587 66.0
TLS2_k127_1305608_12 Protein of unknown function (DUF1501) - - - 0.0000001347 57.0
TLS2_k127_1305608_2 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 463.0
TLS2_k127_1305608_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 443.0
TLS2_k127_1305608_4 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 439.0
TLS2_k127_1305608_5 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 291.0
TLS2_k127_1305608_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007023 272.0
TLS2_k127_1305608_7 - - - - 0.00000000000000000000000000000000000000000000000000004903 206.0
TLS2_k127_1305608_8 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000006814 189.0
TLS2_k127_1307744_0 Protein of unknown function (DUF1549) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 309.0
TLS2_k127_1307744_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000001241 130.0
TLS2_k127_1316919_0 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 395.0
TLS2_k127_1316919_1 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001002 245.0
TLS2_k127_1316919_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003073 250.0
TLS2_k127_1316919_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000006013 203.0
TLS2_k127_1316919_5 Intracellular proteinase inhibitor - - - 0.000000000000000000000000000000002803 143.0
TLS2_k127_1316919_6 - - - - 0.00000000000000000000000000001909 124.0
TLS2_k127_1323867_0 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.00000000000000000000000002844 110.0
TLS2_k127_1323867_1 chaperone-mediated protein complex assembly - - - 0.000000000000000000000000215 119.0
TLS2_k127_1323867_2 chaperone-mediated protein complex assembly - - - 0.00000000009175 74.0
TLS2_k127_1324170_0 protein transport across the cell outer membrane K02453,K03219 - - 9.639e-204 661.0
TLS2_k127_1324170_1 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 620.0
TLS2_k127_1324170_10 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000000000000426 116.0
TLS2_k127_1324170_2 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 335.0
TLS2_k127_1324170_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 346.0
TLS2_k127_1324170_4 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784,K13318,K13322,K16439,K19857 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 322.0
TLS2_k127_1324170_5 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006619 277.0
TLS2_k127_1324170_6 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000003426 234.0
TLS2_k127_1324170_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000008789 228.0
TLS2_k127_1324170_8 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000000002112 125.0
TLS2_k127_1332516_0 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 387.0
TLS2_k127_1332516_1 F-box LRR-repeat protein - - - 0.00000000000000000000000000000000000000000000001079 194.0
TLS2_k127_1332516_2 PFAM secretion protein HlyD family protein - - - 0.0000000000000000000000000000000000000000001873 171.0
TLS2_k127_1332516_3 Chromate transporter K07240 - - 0.00000000000000000000000002174 116.0
TLS2_k127_1332516_4 DinB superfamily - - - 0.00000000000002756 85.0
TLS2_k127_1332516_5 Leucine-rich repeat (LRR) protein K13730 - - 0.00000001341 66.0
TLS2_k127_1332516_6 COG1457 Purine-cytosine permease and related proteins - - - 0.0000009893 57.0
TLS2_k127_1333919_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 415.0
TLS2_k127_1333919_1 pfam abc K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 319.0
TLS2_k127_1333919_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 319.0
TLS2_k127_1333919_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006028 288.0
TLS2_k127_1333919_4 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000004865 216.0
TLS2_k127_1333919_5 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000002487 163.0
TLS2_k127_1345941_0 Cytochrome c - - - 2.177e-236 752.0
TLS2_k127_1345941_1 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 594.0
TLS2_k127_1345941_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 404.0
TLS2_k127_1345941_3 Putative regulatory protein - - - 0.00000000000000000000001025 102.0
TLS2_k127_1359061_0 TrkA-C domain K03316,K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 518.0
TLS2_k127_1359061_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 466.0
TLS2_k127_1359061_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 451.0
TLS2_k127_1359061_3 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 379.0
TLS2_k127_1359061_4 WD40 domain protein beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000001473 217.0
TLS2_k127_1359061_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000001485 169.0
TLS2_k127_1359061_6 PFAM WD40-like beta Propeller - - - 0.000000000000000002654 89.0
TLS2_k127_1359061_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase K01113 - 3.1.3.1 0.000000000000009413 79.0
TLS2_k127_1377793_0 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 452.0
TLS2_k127_1377793_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000008396 147.0
TLS2_k127_1377793_2 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000008705 163.0
TLS2_k127_1383533_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 7.019e-222 704.0
TLS2_k127_1383533_1 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 3.888e-195 614.0
TLS2_k127_1383533_2 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 460.0
TLS2_k127_1383533_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 432.0
TLS2_k127_1383533_4 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 371.0
TLS2_k127_1383533_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 306.0
TLS2_k127_1383533_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000002932 250.0
TLS2_k127_1383533_7 shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000001045 173.0
TLS2_k127_1383533_8 Ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000005311 143.0
TLS2_k127_1386296_0 Peptidase M14, carboxypeptidase A - - - 2.458e-293 925.0
TLS2_k127_1386296_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 389.0
TLS2_k127_1386296_2 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 349.0
TLS2_k127_1386296_3 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000153 285.0
TLS2_k127_1386296_4 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004189 297.0
TLS2_k127_1386296_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000002468 138.0
TLS2_k127_1386296_6 Domain of unknown function (DUF4926) - - - 0.000000000002156 72.0
TLS2_k127_1386296_7 - - - - 0.000001665 54.0
TLS2_k127_1386296_8 Putative zinc-finger - - - 0.00005575 51.0
TLS2_k127_1389057_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1030.0
TLS2_k127_1389057_1 Planctomycete cytochrome C - - - 9.941e-245 795.0
TLS2_k127_1389057_10 PFAM PilT protein domain protein K07063 - - 0.000000000000000000000000000000000009912 142.0
TLS2_k127_1389057_11 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000005144 104.0
TLS2_k127_1389057_12 Ribbon-helix-helix domain - - - 0.00000000000000000000008492 100.0
TLS2_k127_1389057_14 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000006268 62.0
TLS2_k127_1389057_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 608.0
TLS2_k127_1389057_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 590.0
TLS2_k127_1389057_4 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 573.0
TLS2_k127_1389057_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 447.0
TLS2_k127_1389057_6 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 346.0
TLS2_k127_1389057_7 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 341.0
TLS2_k127_1389057_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000326 245.0
TLS2_k127_1389057_9 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000001857 175.0
TLS2_k127_139106_0 peptidyl-tyrosine sulfation - - - 1.478e-194 620.0
TLS2_k127_139106_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 612.0
TLS2_k127_139106_2 PFAM Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001861 282.0
TLS2_k127_139106_3 Psort location Cytoplasmic, score 8.87 K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000002911 253.0
TLS2_k127_139106_4 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000279 219.0
TLS2_k127_139106_5 Tetratricopeptide repeat - - - 0.00000000000000000000002097 109.0
TLS2_k127_139106_6 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000000000002559 101.0
TLS2_k127_1404740_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.857e-244 759.0
TLS2_k127_1404740_1 Protein of unknown function (DUF1549) - - - 1.937e-235 752.0
TLS2_k127_1404740_2 Carboxypeptidase regulatory-like domain - - - 4.448e-223 728.0
TLS2_k127_1404740_3 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 3.254e-220 690.0
TLS2_k127_1404740_4 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 501.0
TLS2_k127_1412627_0 Carboxypeptidase regulatory-like domain - - - 0.0 1459.0
TLS2_k127_1412627_1 peptidyl-tyrosine sulfation - - - 1.786e-217 695.0
TLS2_k127_1412627_10 peptidyl-tyrosine sulfation - - - 0.00000000000000003174 96.0
TLS2_k127_1412627_11 PFAM single-strand binding protein Primosomal replication protein n K03111 - - 0.00008039 50.0
TLS2_k127_1412627_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 614.0
TLS2_k127_1412627_3 Protein of unknown function (DUF1549) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 580.0
TLS2_k127_1412627_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 588.0
TLS2_k127_1412627_5 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 381.0
TLS2_k127_1412627_6 COG3119 Arylsulfatase A and related enzymes K01135 - 3.1.6.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 264.0
TLS2_k127_1412627_7 COG3119 Arylsulfatase A and related enzymes K01135 - 3.1.6.12 0.00000000000000000000000000000000000000000000004604 177.0
TLS2_k127_1412627_8 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000256 171.0
TLS2_k127_1412627_9 translation initiation factor activity - - - 0.00000000000000000000000000009646 134.0
TLS2_k127_1424224_0 Dehydrogenase K00114,K17760,K20936,K21676,K22473 - 1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2 0.0 1092.0
TLS2_k127_1424224_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.68e-287 890.0
TLS2_k127_1424224_11 Belongs to the peptidase S8 family K14645,K20276 - - 0.00000000000000000000000000000001132 137.0
TLS2_k127_1424224_12 Oligogalacturonate lyase K01730 - 4.2.2.6 0.0000000000000000000007121 100.0
TLS2_k127_1424224_13 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000001386 74.0
TLS2_k127_1424224_2 succinate dehydrogenase - - - 3.854e-252 790.0
TLS2_k127_1424224_3 GMC oxidoreductase - - - 4.256e-250 781.0
TLS2_k127_1424224_4 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 300.0
TLS2_k127_1424224_5 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000000000000000000000000000000000001756 214.0
TLS2_k127_1424224_6 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000005222 207.0
TLS2_k127_1424224_7 DinB superfamily - - - 0.0000000000000000000000000000000000000000000001618 173.0
TLS2_k127_1424224_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000008392 148.0
TLS2_k127_1424224_9 metal-dependent protease of the Pad1 Jab1 superfamily - - - 0.00000000000000000000000000000000000003369 157.0
TLS2_k127_1426644_0 lipopolysaccharide transport K22110 - - 0.0 1373.0
TLS2_k127_1426644_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1289.0
TLS2_k127_1426644_10 FES K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 379.0
TLS2_k127_1426644_11 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 319.0
TLS2_k127_1426644_12 4-amino-4-deoxy-L-arabinose transferase activity K16648 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007373 291.0
TLS2_k127_1426644_13 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008181 267.0
TLS2_k127_1426644_14 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01683,K01684 - 4.2.1.5,4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000008637 243.0
TLS2_k127_1426644_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000009996 209.0
TLS2_k127_1426644_16 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000009412 196.0
TLS2_k127_1426644_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000001055 182.0
TLS2_k127_1426644_18 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000005256 178.0
TLS2_k127_1426644_19 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000001085 123.0
TLS2_k127_1426644_2 choline dehydrogenase activity - - - 2.239e-219 691.0
TLS2_k127_1426644_20 Transposase - - - 0.0000000000000000000001072 102.0
TLS2_k127_1426644_21 - - - - 0.00000000000468 70.0
TLS2_k127_1426644_22 Transposase DDE domain - - - 0.00000000004445 66.0
TLS2_k127_1426644_23 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000358 57.0
TLS2_k127_1426644_3 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 587.0
TLS2_k127_1426644_4 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 471.0
TLS2_k127_1426644_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 452.0
TLS2_k127_1426644_6 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 437.0
TLS2_k127_1426644_7 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 417.0
TLS2_k127_1426644_8 Enoyl-(Acyl carrier protein) reductase K00034 - 1.1.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 412.0
TLS2_k127_1426644_9 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 383.0
TLS2_k127_143811_0 Radical SAM - - - 0.0 1151.0
TLS2_k127_143811_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 453.0
TLS2_k127_143811_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 360.0
TLS2_k127_143811_3 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 340.0
TLS2_k127_143811_4 Ferredoxin K02230 - 6.6.1.2 0.0000000000000000000000000000000000000000000001382 175.0
TLS2_k127_143811_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000001466 134.0
TLS2_k127_143811_7 WG containing repeat - - - 0.000000000000000000000396 109.0
TLS2_k127_143811_8 YjbR - - - 0.000000000000000001058 87.0
TLS2_k127_1445091_0 protocatechuate 3,4-dioxygenase activity - - - 1.753e-247 801.0
TLS2_k127_1445091_1 PFAM WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 555.0
TLS2_k127_1445091_10 WD40 repeats - - - 0.00005869 48.0
TLS2_k127_1445091_2 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 546.0
TLS2_k127_1445091_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009617 266.0
TLS2_k127_1445091_4 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001266 220.0
TLS2_k127_1445091_5 universal stress protein - - - 0.000000000000000001415 98.0
TLS2_k127_1445091_6 Protein of unknown function (DUF2283) - - - 0.0000000000000001829 83.0
TLS2_k127_1445091_7 AMP binding - - - 0.000000000000007738 85.0
TLS2_k127_1445091_8 Cytochrome c - - - 0.000000000001725 71.0
TLS2_k127_1445091_9 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000004347 63.0
TLS2_k127_1455339_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.855e-287 898.0
TLS2_k127_1455339_1 phospholipase C - - - 6.959e-210 682.0
TLS2_k127_1462090_0 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 313.0
TLS2_k127_1462090_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000414 207.0
TLS2_k127_1462090_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000006911 221.0
TLS2_k127_1462090_3 2'-5' RNA ligase superfamily K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000008242 186.0
TLS2_k127_1463905_0 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 3.083e-202 632.0
TLS2_k127_1463905_1 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 566.0
TLS2_k127_1463905_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001406 263.0
TLS2_k127_1463905_3 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 - 1.12.99.6 0.000000004148 57.0
TLS2_k127_1467803_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 364.0
TLS2_k127_1467803_1 macromolecule localization K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000478 266.0
TLS2_k127_1467803_2 teichoic acid transport K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000001256 243.0
TLS2_k127_1467803_3 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000008292 197.0
TLS2_k127_1475745_0 Carboxypeptidase regulatory-like domain - - - 0.0 1472.0
TLS2_k127_1475745_1 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 594.0
TLS2_k127_1475745_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 408.0
TLS2_k127_1475745_3 DNA topological change K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000006787 258.0
TLS2_k127_1475745_4 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000002459 217.0
TLS2_k127_1475745_5 Protein of unknown function (DUF1592) - - - 0.000000000000000000000000000000000000000000001067 175.0
TLS2_k127_1475745_6 Cytochrome c - - - 0.00000000000000000000000000000000000007318 158.0
TLS2_k127_1475745_7 DoxX-like family - - - 0.00000000001227 70.0
TLS2_k127_1501995_0 Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004363 288.0
TLS2_k127_1501995_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001455 268.0
TLS2_k127_1501995_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003575 232.0
TLS2_k127_1501995_3 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000537 168.0
TLS2_k127_1501995_4 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0000000000000000000000000000000000000005792 148.0
TLS2_k127_1501995_5 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000004441 142.0
TLS2_k127_1501995_6 iron-sulfur cluster assembly - - - 0.000000000000000000000000001094 119.0
TLS2_k127_1502391_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 3.095e-317 978.0
TLS2_k127_1502391_1 Domain of unknown function (DUF4139) - - - 6.108e-220 701.0
TLS2_k127_1502391_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000005994 169.0
TLS2_k127_1502391_11 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000324 155.0
TLS2_k127_1502391_12 dioxygenase activity - - - 0.00000000003941 67.0
TLS2_k127_1502391_13 IMG reference gene - - - 0.00000003876 55.0
TLS2_k127_1502391_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 609.0
TLS2_k127_1502391_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 490.0
TLS2_k127_1502391_4 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 410.0
TLS2_k127_1502391_5 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 393.0
TLS2_k127_1502391_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000006347 257.0
TLS2_k127_1502391_7 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000003313 235.0
TLS2_k127_1502391_8 transferase activity, transferring acyl groups - - - 0.00000000000000000000000000000000000000000000000000004821 190.0
TLS2_k127_1502391_9 - - - - 0.00000000000000000000000000000000000000000002283 177.0
TLS2_k127_1514670_0 Carboxypeptidase regulatory-like domain - - - 0.0 1306.0
TLS2_k127_1514670_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.221e-301 937.0
TLS2_k127_1514670_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 348.0
TLS2_k127_1514670_11 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 336.0
TLS2_k127_1514670_12 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 336.0
TLS2_k127_1514670_13 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 329.0
TLS2_k127_1514670_14 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 319.0
TLS2_k127_1514670_15 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 300.0
TLS2_k127_1514670_16 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 304.0
TLS2_k127_1514670_17 von Willebrand factor type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
TLS2_k127_1514670_18 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 312.0
TLS2_k127_1514670_19 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 291.0
TLS2_k127_1514670_2 Putative collagen-binding domain of a collagenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 582.0
TLS2_k127_1514670_20 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 289.0
TLS2_k127_1514670_21 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001865 284.0
TLS2_k127_1514670_22 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006097 274.0
TLS2_k127_1514670_23 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000369 239.0
TLS2_k127_1514670_24 PFAM PPIC-type K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000009374 239.0
TLS2_k127_1514670_25 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000003044 204.0
TLS2_k127_1514670_26 PFAM Cupin - - - 0.0000000000000000000000000000000000000000000000001413 180.0
TLS2_k127_1514670_27 NHL repeat - - - 0.0000000000000000000000000000000000000000000001239 182.0
TLS2_k127_1514670_28 cog cog3189 - - - 0.00000000000000000000000000000000000000001365 157.0
TLS2_k127_1514670_29 - - - - 0.000000000000000000000000000000000000001178 152.0
TLS2_k127_1514670_3 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 508.0
TLS2_k127_1514670_30 Helix-turn-helix domain K15539 - - 0.00000000000000000000000000000002214 138.0
TLS2_k127_1514670_31 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000001579 131.0
TLS2_k127_1514670_32 TIR domain - - - 0.000000000000000000000000001609 128.0
TLS2_k127_1514670_33 Protein conserved in bacteria - - - 0.00000000000000007525 85.0
TLS2_k127_1514670_34 DDE superfamily endonuclease - - - 0.0004156 47.0
TLS2_k127_1514670_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 415.0
TLS2_k127_1514670_5 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 402.0
TLS2_k127_1514670_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 379.0
TLS2_k127_1514670_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 376.0
TLS2_k127_1514670_8 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 361.0
TLS2_k127_1514670_9 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 352.0
TLS2_k127_1518324_0 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 304.0
TLS2_k127_1518324_1 TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000119 255.0
TLS2_k127_1518324_2 COGs COG2442 conserved - - - 0.0000000000000000000000000341 109.0
TLS2_k127_1518324_3 - - - - 0.0000001378 59.0
TLS2_k127_1518324_4 - - - - 0.0003197 48.0
TLS2_k127_1518620_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0 1046.0
TLS2_k127_1518620_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 568.0
TLS2_k127_1518620_2 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003347 245.0
TLS2_k127_1518620_3 - - - - 0.000000000000000000000008698 107.0
TLS2_k127_1518620_4 tetratricopeptide repeat - - - 0.00000000000000000000006531 112.0
TLS2_k127_152434_0 secondary active sulfate transmembrane transporter activity K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 466.0
TLS2_k127_152434_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 454.0
TLS2_k127_152434_2 Succinate dehydrogenase fumarate reductase K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000006318 188.0
TLS2_k127_152434_3 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 - - 0.00000000000000000000000000000000000001004 147.0
TLS2_k127_152434_4 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00246 - - 0.00000000000000000000000000000000001386 140.0
TLS2_k127_152434_5 zinc-ribbon domain - - - 0.000009172 57.0
TLS2_k127_152557_0 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 5.271e-219 689.0
TLS2_k127_152557_1 protocatechuate 3,4-dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 509.0
TLS2_k127_152557_10 - - - - 0.00000000000000003545 86.0
TLS2_k127_152557_11 - - - - 0.00000000006756 70.0
TLS2_k127_152557_12 Protein of unknown function (DUF1624) - - - 0.000000001039 59.0
TLS2_k127_152557_13 Domain of Unknown Function (DUF1080) - - - 0.00004144 52.0
TLS2_k127_152557_14 - - - - 0.00006354 54.0
TLS2_k127_152557_15 TIGRFAM RHS repeat-associated core domain - - - 0.0001128 53.0
TLS2_k127_152557_16 myo-inosose-2 dehydratase activity - - - 0.0002878 52.0
TLS2_k127_152557_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 399.0
TLS2_k127_152557_3 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 364.0
TLS2_k127_152557_4 DNA primase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 328.0
TLS2_k127_152557_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000001955 189.0
TLS2_k127_152557_7 Trehalose utilisation - - - 0.0000000000000000000000000000000000005505 143.0
TLS2_k127_152557_8 Domain of unknown function (DUF4258) - - - 0.0000000000000000000000000000000001373 135.0
TLS2_k127_152557_9 Uncharacterised BCR, YnfA/UPF0060 family - - - 0.000000000000000000008952 98.0
TLS2_k127_1542107_0 Protein of unknown function (DUF1549) - - - 9.127e-205 644.0
TLS2_k127_1542107_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 328.0
TLS2_k127_1544009_0 Cytochrome c - - - 5.571e-267 849.0
TLS2_k127_1544009_1 Protein of unknown function (DUF1501) - - - 1.778e-234 734.0
TLS2_k127_1544009_10 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000005469 200.0
TLS2_k127_1544009_11 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000001559 189.0
TLS2_k127_1544009_12 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000002473 127.0
TLS2_k127_1544009_13 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000009997 135.0
TLS2_k127_1544009_14 Disulphide bond corrector protein DsbC - - - 0.00000000000000000000000000001861 124.0
TLS2_k127_1544009_15 Nucleotidyltransferase domain K07075 - - 0.000000000000003283 78.0
TLS2_k127_1544009_16 Protein of unknown function (DUF1549) - - - 0.00000000000003214 82.0
TLS2_k127_1544009_17 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.0000000000006156 70.0
TLS2_k127_1544009_19 Protein of unknown function DUF86 - - - 0.0000000003092 62.0
TLS2_k127_1544009_2 Carboxypeptidase regulatory-like domain - - - 1.796e-222 734.0
TLS2_k127_1544009_22 HupE / UreJ protein - - - 0.000006659 57.0
TLS2_k127_1544009_3 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 548.0
TLS2_k127_1544009_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 515.0
TLS2_k127_1544009_5 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 482.0
TLS2_k127_1544009_6 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 353.0
TLS2_k127_1544009_7 Copper binding periplasmic protein CusF K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004135 269.0
TLS2_k127_1544009_8 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000001584 256.0
TLS2_k127_1544009_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000000000000000000000000000000000001589 222.0
TLS2_k127_1544171_0 transport - - - 3.068e-294 939.0
TLS2_k127_1544171_1 fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 490.0
TLS2_k127_1544171_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 464.0
TLS2_k127_1544171_3 histidyl-tRNA synthetase - - - 0.000000000000000000000000000000005548 140.0
TLS2_k127_1544171_4 HEAT repeats - - - 0.0000000000000000000000008001 111.0
TLS2_k127_1544171_5 iron dependent repressor - - - 0.0000006857 53.0
TLS2_k127_1544171_6 - - - - 0.00003714 49.0
TLS2_k127_1545370_0 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 307.0
TLS2_k127_1545370_1 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 289.0
TLS2_k127_1545370_2 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000007771 250.0
TLS2_k127_1545370_3 Cytochrome c - - - 0.000003349 51.0
TLS2_k127_1551787_0 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 506.0
TLS2_k127_1551787_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 496.0
TLS2_k127_1551787_2 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 421.0
TLS2_k127_1551787_3 - K07039 - - 0.0000000000000000000000000000000006089 135.0
TLS2_k127_1552227_0 Protein of unknown function (DUF1501) - - - 9.844e-243 758.0
TLS2_k127_1552227_1 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 299.0
TLS2_k127_1552227_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001354 272.0
TLS2_k127_1552227_3 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000005318 156.0
TLS2_k127_1552227_4 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000001525 110.0
TLS2_k127_1560943_0 phosphoglucosamine mutase activity K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 551.0
TLS2_k127_1560943_1 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 427.0
TLS2_k127_1560943_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 318.0
TLS2_k127_1560943_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001118 276.0
TLS2_k127_1560943_4 PFAM Abortive infection protein K07052 - - 0.00000000000000000000000000000000000000000000000000000000002348 217.0
TLS2_k127_1560943_5 ribonuclease inhibitor activity - - - 0.00000000000000000000000000000000000000000002511 169.0
TLS2_k127_1560943_6 protein conserved in bacteria - - - 0.0000000000000000000000000004292 118.0
TLS2_k127_1583150_0 ABC transporter transmembrane K18889 - - 1.521e-212 675.0
TLS2_k127_1583150_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 615.0
TLS2_k127_1583150_2 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 535.0
TLS2_k127_1583150_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 526.0
TLS2_k127_1583150_4 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 502.0
TLS2_k127_1583150_5 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 326.0
TLS2_k127_1583150_6 extracellular solute-binding protein, family 1 K22003 - 5.3.3.7 0.0000000000000000000000000000000000000000000000000000000000672 213.0
TLS2_k127_1583150_7 - - - - 0.00000000000000000000000000000000000000000000000003925 183.0
TLS2_k127_1583150_8 DUF218 domain - - - 0.0000000000000000000000000000000000000005624 156.0
TLS2_k127_1583150_9 Protein of unknown function (DUF3592) - - - 0.000444 52.0
TLS2_k127_1584578_0 C-terminal region of aryl-sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 434.0
TLS2_k127_1584578_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 344.0
TLS2_k127_1584578_2 - - - - 0.000000000000000000000000000000000000000000000002862 183.0
TLS2_k127_1584578_3 addiction module antidote protein, CC2985 family - - - 0.00000000000000002676 90.0
TLS2_k127_1590872_0 DNA topological change K03168 - 5.99.1.2 2.261e-201 655.0
TLS2_k127_1590872_1 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 312.0
TLS2_k127_1590872_2 esterase K12686 - - 0.0000000000000000000004817 104.0
TLS2_k127_161864_0 - - - - 2.785e-253 801.0
TLS2_k127_161864_1 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006824 251.0
TLS2_k127_161864_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) - - - 0.00000000000000000000000000000000000000000000000000000000000000002368 233.0
TLS2_k127_161864_3 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000006632 233.0
TLS2_k127_161864_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000007315 196.0
TLS2_k127_161864_5 transcriptional regulator - - - 0.0000000000000000000000000000000000007694 140.0
TLS2_k127_1619113_0 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 465.0
TLS2_k127_1619113_1 Phosphoenolpyruvate hydrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 394.0
TLS2_k127_1619113_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006172 254.0
TLS2_k127_1620985_0 glycolate transport K14393 - - 3.74e-241 754.0
TLS2_k127_1620985_1 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 326.0
TLS2_k127_1620985_2 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003099 232.0
TLS2_k127_1620985_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000007091 201.0
TLS2_k127_1620985_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000003826 189.0
TLS2_k127_1620985_5 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000005323 116.0
TLS2_k127_1621192_0 transport - - - 0.0 1235.0
TLS2_k127_1621192_1 domain, Protein K20276 - - 0.0 1075.0
TLS2_k127_1621192_10 Major facilitator Superfamily K02511,K02575,K13021 - - 0.00000000000000000000000000000000000000000000000000000000000003033 231.0
TLS2_k127_1621192_11 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.00000000000000000000000000000000000000000000000000001993 195.0
TLS2_k127_1621192_12 Chromate transporter K07240 - - 0.0000000000000000000000000000000001344 142.0
TLS2_k127_1621192_13 Tetratricopeptide repeat - - - 0.000000002447 70.0
TLS2_k127_1621192_14 amidohydrolase - - - 0.000002335 49.0
TLS2_k127_1621192_15 Chromate transporter K07240 - - 0.0000127 51.0
TLS2_k127_1621192_16 - - - - 0.00002409 48.0
TLS2_k127_1621192_2 Protein of unknown function (DUF1501) - - - 2.197e-221 692.0
TLS2_k127_1621192_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 8.826e-210 664.0
TLS2_k127_1621192_4 carboxylic acid catabolic process - - - 2.864e-201 632.0
TLS2_k127_1621192_5 translation initiation factor activity K06370 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 458.0
TLS2_k127_1621192_6 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 428.0
TLS2_k127_1621192_7 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 334.0
TLS2_k127_1621192_8 Bacterial transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 315.0
TLS2_k127_1621192_9 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 297.0
TLS2_k127_163049_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 573.0
TLS2_k127_163049_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 459.0
TLS2_k127_163049_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 437.0
TLS2_k127_163049_3 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 374.0
TLS2_k127_163049_4 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 368.0
TLS2_k127_163049_5 competence protein COMEC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005853 281.0
TLS2_k127_163049_6 Group 1 truncated hemoglobin K06886 - - 0.00000000000000000000000000000000000000000000000000003846 191.0
TLS2_k127_163049_7 Transcriptional regulator K13771 - - 0.000000000000000000000000000000000000000000000009338 175.0
TLS2_k127_163654_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 361.0
TLS2_k127_163654_1 Ku70/Ku80 beta-barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 349.0
TLS2_k127_163654_10 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000001229 52.0
TLS2_k127_163654_11 WD-40 repeat - - - 0.00006811 55.0
TLS2_k127_163654_12 Kelch - - - 0.000112 56.0
TLS2_k127_163654_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 334.0
TLS2_k127_163654_3 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004036 284.0
TLS2_k127_163654_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005685 256.0
TLS2_k127_163654_5 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000001201 197.0
TLS2_k127_163654_6 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000013 149.0
TLS2_k127_163654_7 - - - - 0.000000000000235 79.0
TLS2_k127_163654_8 - - - - 0.0000000000006365 74.0
TLS2_k127_163654_9 - - - - 0.000000007173 67.0
TLS2_k127_1642696_0 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 600.0
TLS2_k127_1642696_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 316.0
TLS2_k127_1642696_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000001085 89.0
TLS2_k127_1646079_0 Planctomycete cytochrome C - - - 1.507e-254 807.0
TLS2_k127_1646079_1 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01631,K01684 GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034192,GO:0034194,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.1.2.21,4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 612.0
TLS2_k127_1646079_2 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 388.0
TLS2_k127_1646079_3 carboxylic acid catabolic process K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 331.0
TLS2_k127_1646079_4 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000004407 140.0
TLS2_k127_1646079_5 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000009475 150.0
TLS2_k127_1647138_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1.96e-282 890.0
TLS2_k127_1647138_1 Carboxypeptidase regulatory-like domain - - - 2.549e-267 861.0
TLS2_k127_1647138_10 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000012 279.0
TLS2_k127_1647138_11 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001322 233.0
TLS2_k127_1647138_13 Domain of unknown function (DUF4384) - - - 0.000000000000000000000000000000000000000009714 168.0
TLS2_k127_1647138_14 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000006741 166.0
TLS2_k127_1647138_15 - - - - 0.0000000000000000000000000000000000003205 148.0
TLS2_k127_1647138_16 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000006281 142.0
TLS2_k127_1647138_19 TIGRFAM TonB family K03832 - - 0.000502 52.0
TLS2_k127_1647138_2 Caspase domain - - - 4.765e-261 821.0
TLS2_k127_1647138_3 cell redox homeostasis - - - 9.18e-206 661.0
TLS2_k127_1647138_4 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 612.0
TLS2_k127_1647138_5 Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 568.0
TLS2_k127_1647138_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 512.0
TLS2_k127_1647138_7 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 430.0
TLS2_k127_1647138_8 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 295.0
TLS2_k127_1647138_9 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001132 298.0
TLS2_k127_1648269_0 Protein of unknown function, DUF255 K06888 - - 3.858e-253 800.0
TLS2_k127_1648269_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 561.0
TLS2_k127_1648269_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 364.0
TLS2_k127_1648269_3 response regulator, receiver - - - 0.0000000000000000000839 98.0
TLS2_k127_1648269_4 COG0457 FOG TPR repeat - - - 0.0000001641 56.0
TLS2_k127_1649523_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 474.0
TLS2_k127_1649523_1 Glycosyltransferase like family 2 K11936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 464.0
TLS2_k127_1649523_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000009785 204.0
TLS2_k127_1649523_3 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.00000000000000000000000000000000000000002643 154.0
TLS2_k127_1649523_4 PFAM Plasmid maintenance system killer K07334 - - 0.0000000000000000000000000000000000000003518 150.0
TLS2_k127_1649523_5 Protein of unknown function (DUF433) - - - 0.0000000000000000000608 91.0
TLS2_k127_1649523_6 Tetratricopeptide repeat - - - 0.0002302 54.0
TLS2_k127_1662605_0 Protein of unknown function (DUF1549) - - - 3.281e-281 896.0
TLS2_k127_1662605_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003345 282.0
TLS2_k127_1662605_2 SMART Tetratricopeptide domain protein - - - 0.000002203 57.0
TLS2_k127_166625_0 Protein of unknown function (DUF1553) - - - 0.0 1202.0
TLS2_k127_166625_1 PFAM Cna B domain protein - - - 0.0 1151.0
TLS2_k127_166625_10 cell adhesion involved in biofilm formation - - - 0.00000000000000000896 100.0
TLS2_k127_166625_2 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 677.0
TLS2_k127_166625_3 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 505.0
TLS2_k127_166625_4 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 501.0
TLS2_k127_166625_5 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 490.0
TLS2_k127_166625_6 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 457.0
TLS2_k127_166625_7 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 353.0
TLS2_k127_166625_8 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001406 283.0
TLS2_k127_166625_9 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000004975 248.0
TLS2_k127_1702360_0 PhoD-like phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000489 226.0
TLS2_k127_172522_0 ASPIC and UnbV - - - 9.175e-242 764.0
TLS2_k127_172522_1 ASPIC and UnbV - - - 2.733e-223 722.0
TLS2_k127_172522_2 ASPIC and UnbV - - - 2.377e-201 652.0
TLS2_k127_172522_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 325.0
TLS2_k127_172522_4 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000001176 228.0
TLS2_k127_172522_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001665 222.0
TLS2_k127_172522_6 Membrane - - - 0.0000000000000000000000000001004 134.0
TLS2_k127_172522_7 Tetratricopeptide repeat - - - 0.000000000000002121 90.0
TLS2_k127_1738254_0 PFAM LmbE family protein - - - 5.864e-263 839.0
TLS2_k127_1738254_1 Sodium:solute symporter family - - - 5.234e-212 671.0
TLS2_k127_1738254_2 peptidyl-tyrosine sulfation - - - 0.0007114 47.0
TLS2_k127_1740676_0 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 319.0
TLS2_k127_1740676_1 CHAT domain - - - 0.0000000000000000000000002638 119.0
TLS2_k127_1742075_0 MgtE intracellular - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 476.0
TLS2_k127_1742075_1 Inhibitor of the KinA pathway to sporulation - - - 0.00000000000000000000000000000000004349 136.0
TLS2_k127_1742075_2 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000001768 123.0
TLS2_k127_1742075_4 - - - - 0.000004461 59.0
TLS2_k127_1742075_5 Protein of unknown function, DUF393 - - - 0.00000589 59.0
TLS2_k127_1754508_0 Carboxypeptidase regulatory-like domain - - - 2.175e-248 805.0
TLS2_k127_1754508_1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 595.0
TLS2_k127_1754508_2 Major facilitator Superfamily K03535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 448.0
TLS2_k127_1754508_3 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 364.0
TLS2_k127_1754508_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000007963 248.0
TLS2_k127_1754508_5 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000003275 146.0
TLS2_k127_1775764_0 DNA-K related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 494.0
TLS2_k127_1775764_1 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000007755 177.0
TLS2_k127_1775764_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000001287 77.0
TLS2_k127_1838990_0 cytochrome C - - - 7.598e-280 886.0
TLS2_k127_1838990_1 Domain of unknown function (DUF4976) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 485.0
TLS2_k127_1838990_10 AMP-binding enzyme K12428 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 351.0
TLS2_k127_1838990_11 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 313.0
TLS2_k127_1838990_12 PFAM YdjC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 304.0
TLS2_k127_1838990_13 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002585 289.0
TLS2_k127_1838990_14 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000005005 257.0
TLS2_k127_1838990_15 Alanine racemase, N-terminal domain K18425,K19967 - 4.1.2.42,4.1.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000007152 259.0
TLS2_k127_1838990_16 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000009221 221.0
TLS2_k127_1838990_17 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000002761 218.0
TLS2_k127_1838990_18 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000001474 195.0
TLS2_k127_1838990_19 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.000000000000000000000000000000000000000008321 167.0
TLS2_k127_1838990_2 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 434.0
TLS2_k127_1838990_20 4Fe-4S dicluster domain K05524 - - 0.00000000000000000000000000000000000002094 153.0
TLS2_k127_1838990_21 Bacterial DNA-binding protein K03530 - - 0.0000000000000000000000000000002447 126.0
TLS2_k127_1838990_22 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000000000000000004242 125.0
TLS2_k127_1838990_24 Ankyrin repeat K16726 GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0002376,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007399,GO:0007423,GO:0008150,GO:0009605,GO:0009607,GO:0009653,GO:0009887,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010506,GO:0010507,GO:0010639,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0016043,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0040011,GO:0042692,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0044085,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0045087,GO:0045214,GO:0046530,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051146,GO:0051704,GO:0051707,GO:0051716,GO:0055001,GO:0055002,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071840,GO:0090596,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:1903146,GO:1903147 - 0.000000000000000000000001171 119.0
TLS2_k127_1838990_25 DoxX K15977 - - 0.00000000000000000000001028 107.0
TLS2_k127_1838990_26 Planctomycete cytochrome C - - - 0.00000000000000000000378 108.0
TLS2_k127_1838990_27 Hfq protein K03666 - - 0.0000000000000000006304 89.0
TLS2_k127_1838990_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000001008 87.0
TLS2_k127_1838990_29 - - - - 0.0000000000000004533 79.0
TLS2_k127_1838990_3 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 387.0
TLS2_k127_1838990_30 - - - - 0.000005076 51.0
TLS2_k127_1838990_31 OsmC-like protein - - - 0.00005738 49.0
TLS2_k127_1838990_33 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0001196 55.0
TLS2_k127_1838990_34 Belongs to the 'phage' integrase family - - - 0.0008198 50.0
TLS2_k127_1838990_4 Gluconate K03299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 384.0
TLS2_k127_1838990_5 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 374.0
TLS2_k127_1838990_6 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 368.0
TLS2_k127_1838990_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 371.0
TLS2_k127_1838990_8 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 365.0
TLS2_k127_1838990_9 PFAM ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 336.0
TLS2_k127_187594_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.0 1057.0
TLS2_k127_187594_1 beta-galactosidase activity K01179,K01190,K12308 - 3.2.1.23,3.2.1.4 2.969e-291 913.0
TLS2_k127_187594_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 624.0
TLS2_k127_187594_3 - - - - 0.000001149 50.0
TLS2_k127_1876216_0 Carboxypeptidase regulatory-like domain - - - 3.957e-249 807.0
TLS2_k127_1876216_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 3.314e-203 640.0
TLS2_k127_1876216_2 PFAM amidohydrolase - - - 1.28e-201 642.0
TLS2_k127_1876216_3 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 611.0
TLS2_k127_1876216_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 605.0
TLS2_k127_1876216_5 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 292.0
TLS2_k127_1876216_6 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002307 269.0
TLS2_k127_1889188_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 8.616e-234 734.0
TLS2_k127_1889188_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 4.075e-219 696.0
TLS2_k127_1889188_10 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 293.0
TLS2_k127_1889188_11 regulation of ruffle assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006201 278.0
TLS2_k127_1889188_12 regulation of ruffle assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000033 281.0
TLS2_k127_1889188_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003817 230.0
TLS2_k127_1889188_14 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000001101 221.0
TLS2_k127_1889188_15 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000008666 215.0
TLS2_k127_1889188_16 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000006318 206.0
TLS2_k127_1889188_17 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000000000000000003536 166.0
TLS2_k127_1889188_18 Peptidase family M48 - - - 0.000000000000000000000000000000000000000002915 173.0
TLS2_k127_1889188_19 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000000000001301 141.0
TLS2_k127_1889188_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 588.0
TLS2_k127_1889188_20 von Willebrand factor, type A - - - 0.000000000000000000000000000000000385 146.0
TLS2_k127_1889188_21 alpha-galactosidase K07407 - 3.2.1.22 0.0000000000000000000000000000003746 141.0
TLS2_k127_1889188_22 Glycosyl transferase family 2 - - - 0.00001197 57.0
TLS2_k127_1889188_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 582.0
TLS2_k127_1889188_4 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 472.0
TLS2_k127_1889188_5 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 418.0
TLS2_k127_1889188_6 Major Facilitator Superfamily K03535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 400.0
TLS2_k127_1889188_7 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 345.0
TLS2_k127_1889188_8 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 332.0
TLS2_k127_1889188_9 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 326.0
TLS2_k127_1891583_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 4.386e-219 690.0
TLS2_k127_1891583_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.232e-209 662.0
TLS2_k127_1891583_2 von Willebrand factor (vWF) type A domain K07114 - - 1.012e-202 639.0
TLS2_k127_1891583_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 309.0
TLS2_k127_1908572_0 Cytochrome c - - - 1.434e-195 622.0
TLS2_k127_1908572_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 472.0
TLS2_k127_1932947_0 transport - - - 4.25e-217 715.0
TLS2_k127_1932947_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 534.0
TLS2_k127_1932947_2 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000001759 155.0
TLS2_k127_193425_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000008438 223.0
TLS2_k127_193425_1 PFAM Abortive infection protein K07052 - - 0.000000000000000000000000000000000000000006331 166.0
TLS2_k127_193425_2 Thioesterase superfamily - - - 0.000000000000000000000000000000001144 136.0
TLS2_k127_1934364_0 PFAM Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 593.0
TLS2_k127_1934364_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 542.0
TLS2_k127_1934364_2 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 471.0
TLS2_k127_1934364_3 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 374.0
TLS2_k127_1934364_4 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 366.0
TLS2_k127_1934364_5 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 338.0
TLS2_k127_1934364_6 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001573 238.0
TLS2_k127_1934364_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000001607 100.0
TLS2_k127_1934364_8 Protein of unknown function (DUF3500) - - - 0.00000000000000001055 82.0
TLS2_k127_1934395_0 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 436.0
TLS2_k127_1934395_1 parallel beta-helix repeat - - - 0.00000002592 65.0
TLS2_k127_1935708_0 lipopolysaccharide transport K22110 - - 0.0 1344.0
TLS2_k127_1935708_1 Cytochrome c - - - 7.327e-242 779.0
TLS2_k127_1935708_10 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 380.0
TLS2_k127_1935708_11 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 385.0
TLS2_k127_1935708_12 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 306.0
TLS2_k127_1935708_13 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 302.0
TLS2_k127_1935708_14 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000007536 236.0
TLS2_k127_1935708_15 - - - - 0.000000000000000000000000000000000000000000000000000003701 193.0
TLS2_k127_1935708_16 - - - - 0.00000000000000000000000000000000000005281 157.0
TLS2_k127_1935708_17 Cytochrome C oxidase, cbb3-type, subunit III K16255 - - 0.000000000000000000000000000006431 137.0
TLS2_k127_1935708_18 Biotin-requiring enzyme - - - 0.000000000000000000000001604 110.0
TLS2_k127_1935708_19 - - - - 0.000000000000000000001561 95.0
TLS2_k127_1935708_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.06e-219 693.0
TLS2_k127_1935708_20 - - - - 0.0000000000002662 72.0
TLS2_k127_1935708_21 Protein of unknown function (DUF433) - - - 0.0000000000009099 74.0
TLS2_k127_1935708_22 - - - - 0.000000001124 63.0
TLS2_k127_1935708_23 carboxylic acid catabolic process K01684 - 4.2.1.6 0.000000003829 61.0
TLS2_k127_1935708_24 Protein of unknown function (DUF560) - - - 0.000003781 49.0
TLS2_k127_1935708_3 COG2133 Glucose sorbosone dehydrogenases - - - 1.024e-216 688.0
TLS2_k127_1935708_4 Protein of unknown function (DUF1501) - - - 8.254e-208 655.0
TLS2_k127_1935708_5 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 573.0
TLS2_k127_1935708_6 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 562.0
TLS2_k127_1935708_7 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 510.0
TLS2_k127_1935708_8 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 450.0
TLS2_k127_1935708_9 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 388.0
TLS2_k127_1945334_0 Protein of unknown function (DUF1549) - - - 6.253e-267 836.0
TLS2_k127_1945334_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000002683 212.0
TLS2_k127_1953816_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 6.384e-309 963.0
TLS2_k127_1953816_1 Transposase K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 608.0
TLS2_k127_1953816_2 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 415.0
TLS2_k127_1953816_3 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 400.0
TLS2_k127_1953816_4 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 325.0
TLS2_k127_1953816_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 328.0
TLS2_k127_1953816_6 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000009056 241.0
TLS2_k127_1953816_7 PFAM IS66 Orf2 family protein K07484 - - 0.000000000000000000000000000000000000000001769 157.0
TLS2_k127_1953816_8 PFAM type III restriction protein res subunit - - - 0.0000000000000000000000000000000000292 142.0
TLS2_k127_1953816_9 COG1977 Molybdopterin converting factor, small subunit K03636 - - 0.000000000000000007 96.0
TLS2_k127_1961131_0 Carboxypeptidase regulatory-like domain - - - 2.174e-224 728.0
TLS2_k127_1961131_1 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 622.0
TLS2_k127_1961131_10 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000008849 63.0
TLS2_k127_1961131_2 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 383.0
TLS2_k127_1961131_3 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 347.0
TLS2_k127_1961131_4 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 302.0
TLS2_k127_1961131_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000001141 205.0
TLS2_k127_1961131_7 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000004424 168.0
TLS2_k127_1961131_9 cell redox homeostasis - - - 0.0000000000004144 78.0
TLS2_k127_1961754_0 Thermolysin metallopeptidase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008397 301.0
TLS2_k127_1977043_0 Belongs to the GSP D family K02453 - - 1.15e-202 655.0
TLS2_k127_1977043_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 578.0
TLS2_k127_1977043_10 Type II secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000000001883 175.0
TLS2_k127_1977043_2 acid phosphatase activity K22390 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 456.0
TLS2_k127_1977043_3 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 382.0
TLS2_k127_1977043_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 319.0
TLS2_k127_1977043_5 Pfam:Methyltransf_26 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 309.0
TLS2_k127_1977043_6 Spore coat protein CotH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 307.0
TLS2_k127_1977043_7 oxidation-reduction process K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000004728 222.0
TLS2_k127_1977043_8 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
TLS2_k127_1977043_9 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000001106 201.0
TLS2_k127_2017422_0 Carboxypeptidase regulatory-like domain - - - 1.227e-289 918.0
TLS2_k127_2017422_1 Concanavalin A-like lectin/glucanases superfamily - - - 2.674e-213 691.0
TLS2_k127_2017422_2 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 485.0
TLS2_k127_2017422_3 - - - - 0.000000000000117 82.0
TLS2_k127_2017422_4 - - - - 0.0000000000001697 81.0
TLS2_k127_2017422_5 Belongs to the ompA family - - - 0.00000234 50.0
TLS2_k127_2024822_0 cytochrome C - - - 2.24e-244 785.0
TLS2_k127_2024822_1 Protein of unknown function (DUF1501) - - - 7.039e-198 627.0
TLS2_k127_2024822_2 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 538.0
TLS2_k127_2024822_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 474.0
TLS2_k127_2024822_4 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 466.0
TLS2_k127_2024822_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001903 229.0
TLS2_k127_2024822_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000001003 106.0
TLS2_k127_2024822_7 PFAM Tetratricopeptide repeat - - - 0.0000000003632 72.0
TLS2_k127_20264_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 440.0
TLS2_k127_20264_1 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 354.0
TLS2_k127_20264_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 323.0
TLS2_k127_20264_3 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007902 268.0
TLS2_k127_20264_4 - - - - 0.0000000004272 63.0
TLS2_k127_2032218_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 610.0
TLS2_k127_2032218_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 569.0
TLS2_k127_2032218_2 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000005057 246.0
TLS2_k127_2032218_3 dUTPase K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000001162 214.0
TLS2_k127_2032218_4 membrane organization K07277 - - 0.00000000000000000000000000000000000000000000004746 186.0
TLS2_k127_2033179_0 mandelate racemase muconate lactonizing K08323 - 4.2.1.8 2.27e-215 678.0
TLS2_k127_2033179_1 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 572.0
TLS2_k127_2033179_10 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000005191 83.0
TLS2_k127_2033179_11 Helix-turn-helix XRE-family like proteins - - - 0.00000001254 58.0
TLS2_k127_2033179_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 500.0
TLS2_k127_2033179_3 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 323.0
TLS2_k127_2033179_4 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 310.0
TLS2_k127_2033179_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 314.0
TLS2_k127_2033179_6 cytochrome complex assembly K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001703 280.0
TLS2_k127_2033179_7 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003715 272.0
TLS2_k127_2033179_8 PFAM NHL repeat containing protein K13735 - - 0.0000000000000000000000000000000000000000000000000000000000001176 243.0
TLS2_k127_2033179_9 TonB-dependent receptor - - - 0.000000000000000000000000004866 117.0
TLS2_k127_207099_0 peptidase dimerisation domain - - - 2.495e-204 646.0
TLS2_k127_207099_1 H( )-stimulated, divalent metal cation uptake system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 589.0
TLS2_k127_207099_10 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 310.0
TLS2_k127_207099_11 nucleoside 2-deoxyribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000002994 204.0
TLS2_k127_207099_12 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000001177 140.0
TLS2_k127_207099_13 Tripartite tricarboxylate transporter TctB family - - - 0.0007961 48.0
TLS2_k127_207099_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 542.0
TLS2_k127_207099_3 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 530.0
TLS2_k127_207099_4 PFAM Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 500.0
TLS2_k127_207099_5 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 481.0
TLS2_k127_207099_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008713 464.0
TLS2_k127_207099_7 Belongs to the BshC family K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 463.0
TLS2_k127_207099_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00018 - 1.1.1.26,1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 407.0
TLS2_k127_207099_9 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 374.0
TLS2_k127_2075027_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 412.0
TLS2_k127_2075027_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 337.0
TLS2_k127_2075027_2 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000389 214.0
TLS2_k127_2075027_3 heme a metabolic process K02259,K03110 - - 0.0000000000000000000000000000000000000000000000000000000004289 213.0
TLS2_k127_2075027_4 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000002187 188.0
TLS2_k127_2075027_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000002616 107.0
TLS2_k127_2075027_6 YtxH-like protein - - - 0.0000003988 56.0
TLS2_k127_2076717_0 domain, Protein - - - 0.000000000000000000000000000000000000000002623 166.0
TLS2_k127_2076717_1 Cytochrome c K00406,K20200 - - 0.00000000000000000000000000000322 131.0
TLS2_k127_2076717_2 pyrroloquinoline quinone binding - - - 0.0000000003963 63.0
TLS2_k127_2076717_3 PFAM Manganese containing catalase K07217 - - 0.000000005027 61.0
TLS2_k127_2076717_4 - - - - 0.00000002945 57.0
TLS2_k127_2076717_5 - - - - 0.000004001 54.0
TLS2_k127_2081203_0 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds K01666 - 4.1.3.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 520.0
TLS2_k127_2081203_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 500.0
TLS2_k127_2081203_2 Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds K04073 - 1.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 446.0
TLS2_k127_2081203_3 acetamidase formamidase K01455 - 3.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 309.0
TLS2_k127_2081203_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000006596 219.0
TLS2_k127_2081203_5 Cytidine and deoxycytidylate deaminase zinc-binding region K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000003423 202.0
TLS2_k127_2081203_6 - - - - 0.00000000000000000000000000000004403 133.0
TLS2_k127_2081203_7 Protein of unknown function (DUF1501) - - - 0.000000000000000000000344 96.0
TLS2_k127_2086995_0 Elongation factor G, domain IV K02355 - - 1.137e-307 960.0
TLS2_k127_2086995_1 Putative glutamine amidotransferase - - - 1.334e-294 932.0
TLS2_k127_2086995_10 KR domain K00059,K18337 - 1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378 0.000000000000000000000000000000000000000000000000000000000000000000000008125 253.0
TLS2_k127_2086995_11 SUF system FeS assembly protein K04488 - - 0.000000000000000000000000000000000000000000000000000162 190.0
TLS2_k127_2086995_12 2 iron, 2 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000004327 179.0
TLS2_k127_2086995_13 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000003654 171.0
TLS2_k127_2086995_14 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000007947 168.0
TLS2_k127_2086995_15 FeS assembly SUF system protein - - - 0.000000000000000000000000000000000006949 143.0
TLS2_k127_2086995_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000004727 122.0
TLS2_k127_2086995_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000002693 117.0
TLS2_k127_2086995_18 PFAM transposase IS4 family protein - - - 0.0000000000385 65.0
TLS2_k127_2086995_19 Transposase DDE domain - - - 0.00008087 49.0
TLS2_k127_2086995_2 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 6.451e-264 818.0
TLS2_k127_2086995_3 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 571.0
TLS2_k127_2086995_4 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 540.0
TLS2_k127_2086995_5 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 381.0
TLS2_k127_2086995_6 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 376.0
TLS2_k127_2086995_7 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 370.0
TLS2_k127_2086995_8 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 374.0
TLS2_k127_2086995_9 Sigma-70, region 4 K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 303.0
TLS2_k127_2095698_0 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 490.0
TLS2_k127_2095698_1 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 368.0
TLS2_k127_2095698_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009287 251.0
TLS2_k127_2095698_3 CYTH K05873 - 4.6.1.1 0.00000000000000000000000000000000000000000000000001448 186.0
TLS2_k127_2095698_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000009505 180.0
TLS2_k127_2095698_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000002371 71.0
TLS2_k127_2096979_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.6e-322 1007.0
TLS2_k127_2096979_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 636.0
TLS2_k127_2096979_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 621.0
TLS2_k127_2096979_3 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 502.0
TLS2_k127_2096979_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 469.0
TLS2_k127_2096979_5 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 360.0
TLS2_k127_2096979_6 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003858 296.0
TLS2_k127_2096979_7 - - - - 0.00000000000001921 86.0
TLS2_k127_210666_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.756e-236 739.0
TLS2_k127_210666_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 580.0
TLS2_k127_210666_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 299.0
TLS2_k127_210666_11 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 288.0
TLS2_k127_210666_12 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000001394 165.0
TLS2_k127_210666_13 - - - - 0.0000000000000000000000000000000382 133.0
TLS2_k127_210666_15 Ribbon-helix-helix protein, copG family - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 - 0.0002123 47.0
TLS2_k127_210666_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 561.0
TLS2_k127_210666_3 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 561.0
TLS2_k127_210666_4 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 502.0
TLS2_k127_210666_5 amidohydrolase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 458.0
TLS2_k127_210666_6 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 419.0
TLS2_k127_210666_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 387.0
TLS2_k127_210666_8 PFAM peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 377.0
TLS2_k127_210666_9 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 314.0
TLS2_k127_21108_0 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 3.832e-300 960.0
TLS2_k127_21108_1 regulation of response to stimulus - - - 1.616e-244 771.0
TLS2_k127_21108_10 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000002259 241.0
TLS2_k127_21108_11 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000007406 213.0
TLS2_k127_21108_12 SMART Pyrrolo-quinoline quinone K17713 - - 0.00000000000000000000000000000000000000000000000000007299 202.0
TLS2_k127_21108_13 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.000000000000000000000000000000000000000000000006863 191.0
TLS2_k127_21108_14 beta-propeller repeat - - - 0.00000000000000000000000000000000000000002715 162.0
TLS2_k127_21108_15 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000001827 156.0
TLS2_k127_21108_16 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000000003763 94.0
TLS2_k127_21108_19 repeat-containing protein - - - 0.000000000002031 81.0
TLS2_k127_21108_2 Sigma-70 region 3 K03086 - - 1.35e-198 630.0
TLS2_k127_21108_20 self proteolysis - - - 0.00003359 47.0
TLS2_k127_21108_3 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 596.0
TLS2_k127_21108_4 alginic acid biosynthetic process K01729 - 4.2.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 555.0
TLS2_k127_21108_5 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 525.0
TLS2_k127_21108_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 489.0
TLS2_k127_21108_7 aminopeptidase activity K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 470.0
TLS2_k127_21108_8 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 490.0
TLS2_k127_21108_9 Pyridoxal phosphate biosynthetic protein PdxA K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 385.0
TLS2_k127_2114694_0 surface antigen variable number - - - 1.343e-225 734.0
TLS2_k127_2114694_1 MoeZ MoeB domain K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 438.0
TLS2_k127_2123901_0 Carboxypeptidase regulatory-like domain - - - 0.0 1157.0
TLS2_k127_2123901_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 5.335e-217 687.0
TLS2_k127_2123901_10 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000005639 251.0
TLS2_k127_2123901_11 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000619 183.0
TLS2_k127_2123901_12 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000009231 166.0
TLS2_k127_2123901_13 amine dehydrogenase activity K12287 - - 0.000000000000000000000000000000000000001458 167.0
TLS2_k127_2123901_14 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000008407 151.0
TLS2_k127_2123901_15 BNR repeat-like domain - - - 0.0000000000000000000000001052 124.0
TLS2_k127_2123901_17 Universal stress protein family - - - 0.00006128 52.0
TLS2_k127_2123901_2 PFAM Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 557.0
TLS2_k127_2123901_3 PFAM Glycosyl transferase, family K00756,K00758 - 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 554.0
TLS2_k127_2123901_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 523.0
TLS2_k127_2123901_5 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 456.0
TLS2_k127_2123901_6 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 406.0
TLS2_k127_2123901_7 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 393.0
TLS2_k127_2123901_8 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 344.0
TLS2_k127_2123901_9 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006631 298.0
TLS2_k127_2124587_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 6.23e-227 710.0
TLS2_k127_2124587_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 551.0
TLS2_k127_2124587_2 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 454.0
TLS2_k127_2124587_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 442.0
TLS2_k127_2124587_4 Belongs to the xylose isomerase family K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000002079 209.0
TLS2_k127_2124587_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000005008 160.0
TLS2_k127_2124587_6 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000008087 139.0
TLS2_k127_2124587_7 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.0000000000000000000002801 107.0
TLS2_k127_2124587_8 Sigma-70 region 2 K03088 - - 0.0000000000000000001957 97.0
TLS2_k127_2162178_0 Planctomycete cytochrome C - - - 1.294e-194 643.0
TLS2_k127_2162178_1 Protein of unknown function (DUF1501) - - - 7.466e-194 614.0
TLS2_k127_2162178_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 566.0
TLS2_k127_2162178_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 503.0
TLS2_k127_2162178_4 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009885 477.0
TLS2_k127_2162178_5 Fic/DOC family - - - 0.000000000000000000000000000000000000000005342 158.0
TLS2_k127_2162178_6 protein conserved in bacteria K19166 - - 0.00000000000000000001348 94.0
TLS2_k127_2162178_7 regulator K18831 - - 0.0000000002006 66.0
TLS2_k127_2162910_0 Prolyl oligopeptidase K01322 - 3.4.21.26 1.258e-315 981.0
TLS2_k127_2162910_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 7.548e-314 974.0
TLS2_k127_2162910_10 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000813 280.0
TLS2_k127_2162910_11 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000001611 259.0
TLS2_k127_2162910_12 PQQ enzyme repeat K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000001859 188.0
TLS2_k127_2162910_13 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000008949 177.0
TLS2_k127_2162910_14 PIN domain - - - 0.00000000000000000000000000000000000000000007301 164.0
TLS2_k127_2162910_15 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000061 138.0
TLS2_k127_2162910_16 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000006554 129.0
TLS2_k127_2162910_17 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000000000000000000007631 118.0
TLS2_k127_2162910_18 YtxH-like protein - - - 0.00000000000000001207 86.0
TLS2_k127_2162910_2 - - - - 2.286e-225 721.0
TLS2_k127_2162910_20 Antitoxin Phd_YefM, type II toxin-antitoxin system - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00000000000003269 84.0
TLS2_k127_2162910_21 - - - - 0.00000000000005641 81.0
TLS2_k127_2162910_22 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000001807 69.0
TLS2_k127_2162910_23 - - - - 0.0000000000272 68.0
TLS2_k127_2162910_24 Glycosyl transferase, family 2 K20444 - - 0.000000002134 70.0
TLS2_k127_2162910_25 Pregnancy-associated plasma protein-A - - - 0.00001854 55.0
TLS2_k127_2162910_26 Pregnancy-associated plasma protein-A - - - 0.0001671 49.0
TLS2_k127_2162910_3 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 4.18e-203 637.0
TLS2_k127_2162910_4 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 609.0
TLS2_k127_2162910_5 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 619.0
TLS2_k127_2162910_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 556.0
TLS2_k127_2162910_7 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 502.0
TLS2_k127_2162910_8 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 519.0
TLS2_k127_2162910_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 419.0
TLS2_k127_2166124_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 561.0
TLS2_k127_2177957_0 MreB/Mbl protein - - - 3.438e-247 779.0
TLS2_k127_2177957_1 DNA-K related protein - - - 7.244e-201 637.0
TLS2_k127_2177957_2 Domain of unknown function (DUF2760) - - - 0.0000000000000000000000000000000000000000001952 164.0
TLS2_k127_2186712_0 Myo-inositol oxygenase K00469 - 1.13.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 420.0
TLS2_k127_2186712_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004588 255.0
TLS2_k127_2186712_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009847 237.0
TLS2_k127_2186712_3 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000001377 233.0
TLS2_k127_2186712_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000005131 197.0
TLS2_k127_2186712_5 Membrane - - - 0.0000000000000000000000000000000000000000000004949 169.0
TLS2_k127_2186712_7 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K00034,K00059 - 1.1.1.100,1.1.1.47 0.000255 47.0
TLS2_k127_2196840_0 Domain of unknown function K03737 - 1.2.7.1 0.0 1610.0
TLS2_k127_2196840_1 Carboxypeptidase regulatory-like domain - - - 0.0 1141.0
TLS2_k127_2196840_10 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004567 278.0
TLS2_k127_2196840_11 Male sterility protein K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000009042 275.0
TLS2_k127_2196840_12 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005257 265.0
TLS2_k127_2196840_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008304 270.0
TLS2_k127_2196840_14 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003583 250.0
TLS2_k127_2196840_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000008106 213.0
TLS2_k127_2196840_16 Cytochrome c - - - 0.000000000000000000000000000000000006329 147.0
TLS2_k127_2196840_17 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.000000000000000000000000000000000009122 147.0
TLS2_k127_2196840_19 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000005356 140.0
TLS2_k127_2196840_2 Protein of unknown function (DUF1549) - - - 0.0 1127.0
TLS2_k127_2196840_20 SpoVT / AbrB like domain K07172 - - 0.00000000000000000006541 92.0
TLS2_k127_2196840_22 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000001971 67.0
TLS2_k127_2196840_23 - - - - 0.00000001568 66.0
TLS2_k127_2196840_24 Protein of unknown function (DUF433) - - - 0.00009953 48.0
TLS2_k127_2196840_25 SPTR Helix-turn-helix protein, CopG family protein - - - 0.000146 48.0
TLS2_k127_2196840_26 - - - - 0.0003244 48.0
TLS2_k127_2196840_27 Protein of unknown function (DUF433) - - - 0.0003288 50.0
TLS2_k127_2196840_28 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0005221 45.0
TLS2_k127_2196840_3 Protein of unknown function (DUF1501) - - - 1.606e-235 738.0
TLS2_k127_2196840_4 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 550.0
TLS2_k127_2196840_5 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 462.0
TLS2_k127_2196840_6 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 445.0
TLS2_k127_2196840_7 PBP superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 426.0
TLS2_k127_2196840_8 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 421.0
TLS2_k127_2196840_9 slime layer polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 384.0
TLS2_k127_2201210_0 Terminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 563.0
TLS2_k127_2201210_1 transposase activity - - - 0.000000000000000000000000000000000000578 145.0
TLS2_k127_2201210_2 Protein of unknown function (DUF3489) - - - 0.00000000000002744 82.0
TLS2_k127_2202054_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 603.0
TLS2_k127_2202054_1 Allophanate hydrolase K01457 - 3.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 403.0
TLS2_k127_2202054_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 304.0
TLS2_k127_2202054_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 292.0
TLS2_k127_2202054_4 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000002875 259.0
TLS2_k127_2202054_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000001003 188.0
TLS2_k127_2202054_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000001749 177.0
TLS2_k127_2202054_7 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000007117 119.0
TLS2_k127_2202054_8 - - - - 0.00000000468 64.0
TLS2_k127_2202054_9 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.00006777 50.0
TLS2_k127_2209043_0 Carboxypeptidase regulatory-like domain - - - 0.0 1028.0
TLS2_k127_2209043_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 563.0
TLS2_k127_2209043_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008589 514.0
TLS2_k127_2209043_3 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 396.0
TLS2_k127_2209043_4 Glycosyl transferase, family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000003041 195.0
TLS2_k127_2209043_5 PFAM Tetratricopeptide repeat - - - 0.0000000624 65.0
TLS2_k127_2225299_0 Pyrrolo-quinoline quinone K00117 - 1.1.5.2 2.464e-220 700.0
TLS2_k127_2225299_1 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 574.0
TLS2_k127_2225299_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 295.0
TLS2_k127_2225299_3 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004425 287.0
TLS2_k127_2225299_4 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000002429 214.0
TLS2_k127_2225299_5 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000003524 147.0
TLS2_k127_2264979_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 355.0
TLS2_k127_2264979_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000005862 169.0
TLS2_k127_2264979_2 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 0.00000000001631 73.0
TLS2_k127_2268358_0 type VI secretion protein K11900,K11901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 429.0
TLS2_k127_2280369_0 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 602.0
TLS2_k127_2280369_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 351.0
TLS2_k127_2280369_2 Cytochrome c - - - 0.000000000000000000000000000000000000000003184 165.0
TLS2_k127_2280369_3 PFAM Integrase catalytic region - - - 0.00006949 48.0
TLS2_k127_2282087_0 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 400.0
TLS2_k127_2282087_2 PQQ-like domain - - - 0.0000000000000000002062 89.0
TLS2_k127_228494_0 Protein of unknown function (DUF1549) - - - 5.711e-290 930.0
TLS2_k127_228494_1 Protein of unknown function (DUF229) - - - 4.593e-234 732.0
TLS2_k127_228494_2 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 587.0
TLS2_k127_228494_3 beta-propeller repeat - - - 0.00000000000000000000000000000000000000002952 166.0
TLS2_k127_228494_4 PFAM Bacterial regulatory proteins, gntR family K05799 - - 0.0000000000000000000000000000000001962 141.0
TLS2_k127_228494_5 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000002239 77.0
TLS2_k127_2289029_0 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 405.0
TLS2_k127_2289029_1 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005665 233.0
TLS2_k127_2289029_2 transcriptional regulator - - - 0.000000000000000000000000000000001644 132.0
TLS2_k127_2294925_0 N-acetyldiaminopimelate deacetylase activity K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 610.0
TLS2_k127_2294925_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006141 255.0
TLS2_k127_2294925_2 PFAM amine oxidase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000002819 229.0
TLS2_k127_2294925_3 YjbR - - - 0.00000000000000000000000000000000000000000000007405 171.0
TLS2_k127_2312289_0 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 514.0
TLS2_k127_2312289_1 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 462.0
TLS2_k127_2312289_2 Bestrophin, RFP-TM, chloride channel K08994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 383.0
TLS2_k127_2312289_3 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 303.0
TLS2_k127_2312289_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000001125 239.0
TLS2_k127_2312289_5 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000002374 190.0
TLS2_k127_2314404_0 Histidine kinase - - - 0.0 1031.0
TLS2_k127_2314404_1 Carboxypeptidase regulatory-like domain - - - 0.0 1029.0
TLS2_k127_2314404_10 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 318.0
TLS2_k127_2314404_11 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 316.0
TLS2_k127_2314404_12 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01639,K01714 - 4.1.3.3,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 288.0
TLS2_k127_2314404_13 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001578 239.0
TLS2_k127_2314404_14 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000001264 223.0
TLS2_k127_2314404_15 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000007808 205.0
TLS2_k127_2314404_16 peptidase activity - - - 0.000000000000000000000000000000000000000000000000003397 191.0
TLS2_k127_2314404_17 peptidase activity - - - 0.0000000000000000000000000000000000000005971 161.0
TLS2_k127_2314404_18 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000003362 88.0
TLS2_k127_2314404_19 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000006994 80.0
TLS2_k127_2314404_2 Peptidase M56 - - - 4.757e-239 750.0
TLS2_k127_2314404_21 phage tail tape measure protein - - - 0.00000006881 64.0
TLS2_k127_2314404_22 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000003157 54.0
TLS2_k127_2314404_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 7.929e-221 693.0
TLS2_k127_2314404_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 493.0
TLS2_k127_2314404_5 thiosulfate sulfurtransferase activity K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 456.0
TLS2_k127_2314404_6 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 409.0
TLS2_k127_2314404_7 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 421.0
TLS2_k127_2314404_8 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 355.0
TLS2_k127_2314404_9 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 330.0
TLS2_k127_2326455_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 6.315e-233 726.0
TLS2_k127_2326455_1 alpha-L-fucosidase K15923 - 3.2.1.51 1.724e-206 661.0
TLS2_k127_2359678_0 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000003921 235.0
TLS2_k127_2359678_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000004977 219.0
TLS2_k127_2359678_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000001442 127.0
TLS2_k127_2359678_3 transport - - - 0.00000000000000000009002 95.0
TLS2_k127_2359678_4 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000004564 90.0
TLS2_k127_2359678_5 Carboxypeptidase regulatory-like domain - - - 0.000000000001762 73.0
TLS2_k127_2359678_6 Carboxypeptidase regulatory-like domain - - - 0.00000000163 66.0
TLS2_k127_2378595_0 - - - - 1.691e-284 885.0
TLS2_k127_2378595_1 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 560.0
TLS2_k127_2378595_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002905 282.0
TLS2_k127_2378595_3 CDGSH-type zinc finger. Function unknown. - - - 0.0000000000000000000000000000000000000000000000000000001643 202.0
TLS2_k127_2378595_4 - - - - 0.0000000000000000000000000000000000000000003466 168.0
TLS2_k127_2378595_5 - - - - 0.0000000000000000000000000000000000006719 145.0
TLS2_k127_2378595_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000001225 100.0
TLS2_k127_2378595_7 Belongs to the UPF0312 family - - - 0.000000000001172 77.0
TLS2_k127_2395339_0 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 348.0
TLS2_k127_2395339_1 NmrA-like family K19267 - 1.6.5.2 0.0000000000000000000000000000001655 128.0
TLS2_k127_2395339_2 Cytochrome P460 - - - 0.0000000000000000000000000002691 119.0
TLS2_k127_23956_0 ATP-dependent DNA helicase activity K01144,K16898 - 3.1.11.5,3.6.4.12 1.994e-208 691.0
TLS2_k127_23956_1 exonuclease activity K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 542.0
TLS2_k127_23956_10 cell redox homeostasis K03671 - - 0.00000000000000000000000000004725 126.0
TLS2_k127_23956_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 492.0
TLS2_k127_23956_3 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 443.0
TLS2_k127_23956_4 Glycosyl hydrolase family 46 K01233 - 3.2.1.132 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 342.0
TLS2_k127_23956_5 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 306.0
TLS2_k127_23956_6 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002067 301.0
TLS2_k127_23956_7 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K04042,K16881 - 2.3.1.157,2.7.7.13,2.7.7.23,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000009673 252.0
TLS2_k127_23956_8 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000005576 207.0
TLS2_k127_23956_9 carboxylic acid catabolic process K01706 - 4.2.1.40 0.00000000000000000000000000000000000000000000005897 184.0
TLS2_k127_2396313_0 Protein of unknown function (DUF1553) - - - 0.0 1082.0
TLS2_k127_2396313_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.552e-320 1005.0
TLS2_k127_2396313_10 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 320.0
TLS2_k127_2396313_11 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000296 283.0
TLS2_k127_2396313_12 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001697 244.0
TLS2_k127_2396313_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000001597 216.0
TLS2_k127_2396313_14 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000003879 209.0
TLS2_k127_2396313_15 Predicted metal-binding protein (DUF2103) - - - 0.00000000000000000000000000000001095 139.0
TLS2_k127_2396313_16 Hsp20/alpha crystallin family K13993 - - 0.00000000002162 73.0
TLS2_k127_2396313_17 - - - - 0.0000000003171 72.0
TLS2_k127_2396313_2 TonB-dependent Receptor Plug Domain - - - 4.46e-283 902.0
TLS2_k127_2396313_3 Protein of unknown function (DUF1501) - - - 1.182e-238 758.0
TLS2_k127_2396313_4 Wd-40 repeat - - - 9.743e-224 719.0
TLS2_k127_2396313_5 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 2.483e-201 634.0
TLS2_k127_2396313_6 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 642.0
TLS2_k127_2396313_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 506.0
TLS2_k127_2396313_8 PFAM aminotransferase class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 439.0
TLS2_k127_2396313_9 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 439.0
TLS2_k127_2398274_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000002237 222.0
TLS2_k127_2398274_1 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000005005 204.0
TLS2_k127_2398274_2 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.0000000000000000000000000000000000000000000000006893 182.0
TLS2_k127_2419113_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1064.0
TLS2_k127_2419113_1 domain, Protein - - - 8.274e-293 942.0
TLS2_k127_2419113_2 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 495.0
TLS2_k127_2419113_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 299.0
TLS2_k127_2419113_4 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000002205 243.0
TLS2_k127_2419113_5 Protein of unknown function (DUF433) - - - 0.0000000000000000000000005625 107.0
TLS2_k127_2447868_0 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 605.0
TLS2_k127_2447868_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 390.0
TLS2_k127_2447868_2 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 258.0
TLS2_k127_2447868_3 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000000000000000001337 118.0
TLS2_k127_2462971_0 anaphase-promoting complex binding - - - 3.894e-299 932.0
TLS2_k127_2462971_1 Protein of unknown function (DUF1501) - - - 9.177e-244 760.0
TLS2_k127_2462971_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 453.0
TLS2_k127_2462971_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 423.0
TLS2_k127_2462971_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 386.0
TLS2_k127_2462971_5 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 325.0
TLS2_k127_2462971_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003833 258.0
TLS2_k127_2462971_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000003279 190.0
TLS2_k127_2479157_0 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 527.0
TLS2_k127_2479157_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 302.0
TLS2_k127_2479157_2 Bacterial regulatory proteins, luxR family K03088 - - 0.000000000000000000000000000000000000000000000000000000000002258 214.0
TLS2_k127_2479157_3 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000233 190.0
TLS2_k127_2479157_4 aldo keto reductase family - - - 0.0000000000000000000000000000000000000000000000000006057 203.0
TLS2_k127_2479157_5 RNA recognition motif - - - 0.00000000000000000000000000000000000009242 143.0
TLS2_k127_2479157_7 - - - - 0.0000000000000000000000001271 114.0
TLS2_k127_252059_0 TonB-dependent receptor - - - 0.0 1172.0
TLS2_k127_252059_1 protocatechuate 3,4-dioxygenase activity - - - 2.616e-222 732.0
TLS2_k127_252059_10 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000001159 225.0
TLS2_k127_252059_11 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000001617 144.0
TLS2_k127_252059_12 cheY-homologous receiver domain - - - 0.00000000000000000000000000000001014 142.0
TLS2_k127_252059_13 - - - - 0.00000000000000000000000002047 118.0
TLS2_k127_252059_14 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000001294 114.0
TLS2_k127_252059_15 Sigma factor PP2C-like phosphatases K07315,K07680 - 2.7.13.3,3.1.3.3 0.00000000000000000000008418 112.0
TLS2_k127_252059_16 - - - - 0.0006272 49.0
TLS2_k127_252059_2 DegT/DnrJ/EryC1/StrS aminotransferase family K01740 - 2.5.1.49 5.786e-207 674.0
TLS2_k127_252059_3 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 559.0
TLS2_k127_252059_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 430.0
TLS2_k127_252059_5 nucleic acid binding K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 407.0
TLS2_k127_252059_6 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 391.0
TLS2_k127_252059_7 of nitrite reductase and ring-hydroxylating dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 360.0
TLS2_k127_252059_8 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 357.0
TLS2_k127_252059_9 Cupin 2, conserved barrel domain protein K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 305.0
TLS2_k127_2530923_0 Protein of unknown function (DUF1501) - - - 6.319e-216 679.0
TLS2_k127_2530923_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 425.0
TLS2_k127_2530923_2 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 399.0
TLS2_k127_2530923_3 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000005404 195.0
TLS2_k127_2530923_4 Transcriptional regulator - - - 0.00003309 55.0
TLS2_k127_2530923_5 Xylose isomerase-like TIM barrel - - - 0.0007204 44.0
TLS2_k127_25336_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 526.0
TLS2_k127_25336_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 355.0
TLS2_k127_25336_2 - - - - 0.00000000000000000000000000000000000000000000000000001807 205.0
TLS2_k127_25336_3 CHAT domain - - - 0.0000000000000000000000005098 112.0
TLS2_k127_25336_4 Tetratricopeptide repeat - - - 0.0000000000000001409 94.0
TLS2_k127_25336_5 - - - - 0.00000000002012 70.0
TLS2_k127_2538388_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 5.266e-227 713.0
TLS2_k127_2540782_0 LOR/SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 610.0
TLS2_k127_2540782_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 595.0
TLS2_k127_2540782_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000005308 198.0
TLS2_k127_2540782_3 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000314 131.0
TLS2_k127_2545294_0 - - - - 0.000000000000000000000000000002259 123.0
TLS2_k127_2545294_1 domain, Protein - - - 0.00000000000000000000002294 107.0
TLS2_k127_2545294_2 InterPro IPR007367 - - - 0.00000000000003429 78.0
TLS2_k127_2550741_0 Protein of unknown function (DUF1501) - - - 3.169e-207 654.0
TLS2_k127_2550741_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 407.0
TLS2_k127_2550741_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000001947 113.0
TLS2_k127_2557019_0 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 497.0
TLS2_k127_2557019_1 H( )-stimulated, divalent metal cation uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 414.0
TLS2_k127_2557019_10 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000005706 192.0
TLS2_k127_2557019_11 proteolysis - - - 0.00000000000000000000000000000000000000000000000005524 201.0
TLS2_k127_2557019_12 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000004873 149.0
TLS2_k127_2557019_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 398.0
TLS2_k127_2557019_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 366.0
TLS2_k127_2557019_4 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 352.0
TLS2_k127_2557019_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 316.0
TLS2_k127_2557019_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 303.0
TLS2_k127_2557019_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000009531 237.0
TLS2_k127_2557019_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000001987 215.0
TLS2_k127_2557019_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000009648 205.0
TLS2_k127_2558268_0 chlorophyll binding - - - 1.095e-197 652.0
TLS2_k127_2558268_1 DEAD DEAH box K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 460.0
TLS2_k127_2558268_2 HupE / UreJ protein - - - 0.00000000000000000007532 93.0
TLS2_k127_2558268_3 - - - - 0.000000000004423 69.0
TLS2_k127_2587668_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1711.0
TLS2_k127_2587668_1 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 555.0
TLS2_k127_2587668_2 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 377.0
TLS2_k127_2587668_3 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000008395 229.0
TLS2_k127_2587668_4 - - - - 0.000000000000000000006185 97.0
TLS2_k127_2587668_5 Protein of unknown function (DUF433) - - - 0.0000000000002182 73.0
TLS2_k127_2594043_0 PFAM Cytochrome c assembly protein K02198 - - 9.996e-292 909.0
TLS2_k127_2594043_1 Carboxypeptidase regulatory-like domain - - - 1.624e-247 797.0
TLS2_k127_2594043_10 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005137 269.0
TLS2_k127_2594043_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006442 246.0
TLS2_k127_2594043_12 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000001999 232.0
TLS2_k127_2594043_13 SET domain K07117 - - 0.0000000000000000000000000000000000000000000005029 172.0
TLS2_k127_2594043_14 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000003344 174.0
TLS2_k127_2594043_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000003937 166.0
TLS2_k127_2594043_16 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000005437 176.0
TLS2_k127_2594043_17 - - - - 0.00000000000000000000000000000000000003176 149.0
TLS2_k127_2594043_18 cytochrome complex assembly K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.000000000000000000006001 100.0
TLS2_k127_2594043_19 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 0.000001124 59.0
TLS2_k127_2594043_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 641.0
TLS2_k127_2594043_3 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 379.0
TLS2_k127_2594043_4 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 374.0
TLS2_k127_2594043_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 350.0
TLS2_k127_2594043_6 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) K01083 - 3.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 333.0
TLS2_k127_2594043_7 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 310.0
TLS2_k127_2594043_8 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 297.0
TLS2_k127_2594043_9 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 291.0
TLS2_k127_260333_0 Dehydrogenase E1 component K11381 - 1.2.4.4 9.671e-309 959.0
TLS2_k127_260333_1 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 8.572e-224 706.0
TLS2_k127_260333_2 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 377.0
TLS2_k127_260333_3 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 302.0
TLS2_k127_260333_4 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 301.0
TLS2_k127_260333_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001124 231.0
TLS2_k127_260333_6 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 0.0000001163 63.0
TLS2_k127_260333_7 PFAM oxidoreductase domain protein K00118 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.1.99.28 0.0001758 53.0
TLS2_k127_2607452_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 431.0
TLS2_k127_2607452_1 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 383.0
TLS2_k127_2611634_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 372.0
TLS2_k127_2611634_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 329.0
TLS2_k127_2611634_2 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000001457 245.0
TLS2_k127_2611634_3 deoxyhypusine monooxygenase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000001266 147.0
TLS2_k127_2611634_4 microtubule motor activity K10407 GO:0000003,GO:0000226,GO:0000280,GO:0000902,GO:0000904,GO:0000910,GO:0002064,GO:0002065,GO:0002066,GO:0002119,GO:0002164,GO:0002376,GO:0002478,GO:0002495,GO:0002504,GO:0003006,GO:0003674,GO:0003774,GO:0003777,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005829,GO:0005856,GO:0005871,GO:0005875,GO:0005929,GO:0006810,GO:0006886,GO:0006890,GO:0006928,GO:0006996,GO:0007010,GO:0007017,GO:0007018,GO:0007049,GO:0007097,GO:0007143,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007304,GO:0007306,GO:0007399,GO:0007409,GO:0008088,GO:0008092,GO:0008104,GO:0008150,GO:0009653,GO:0009791,GO:0009888,GO:0009987,GO:0010927,GO:0010970,GO:0012505,GO:0015031,GO:0015630,GO:0015631,GO:0015833,GO:0016020,GO:0016043,GO:0016049,GO:0016192,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016938,GO:0017111,GO:0019882,GO:0019884,GO:0019886,GO:0019894,GO:0019953,GO:0022008,GO:0022402,GO:0022411,GO:0022412,GO:0022414,GO:0022607,GO:0030030,GO:0030154,GO:0030182,GO:0030424,GO:0030426,GO:0030427,GO:0030473,GO:0030703,GO:0030705,GO:0030707,GO:0030855,GO:0031175,GO:0031410,GO:0031967,GO:0031975,GO:0031982,GO:0032501,GO:0032502,GO:0032504,GO:0032984,GO:0032988,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033206,GO:0033267,GO:0034613,GO:0035253,GO:0035418,GO:0035617,GO:0036477,GO:0040007,GO:0040011,GO:0040038,GO:0042886,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043933,GO:0044085,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0045184,GO:0046843,GO:0046907,GO:0048002,GO:0048193,GO:0048285,GO:0048468,GO:0048477,GO:0048489,GO:0048588,GO:0048589,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048675,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0051179,GO:0051234,GO:0051293,GO:0051295,GO:0051301,GO:0051321,GO:0051640,GO:0051641,GO:0051647,GO:0051648,GO:0051649,GO:0051650,GO:0051653,GO:0051656,GO:0051704,GO:0060429,GO:0060560,GO:0061564,GO:0061640,GO:0070727,GO:0071702,GO:0071705,GO:0071826,GO:0071840,GO:0072384,GO:0097458,GO:0097479,GO:0097480,GO:0097708,GO:0099003,GO:0099111,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0140013,GO:0150034,GO:1903008,GO:1903046,GO:1990138 - 0.0000000000000000000003453 110.0
TLS2_k127_2611634_5 Tetratricopeptide repeat - - - 0.000000000000000000001197 112.0
TLS2_k127_2611634_6 sequence-specific DNA binding - - - 0.00000000000002333 81.0
TLS2_k127_2614837_0 PFAM Peptidase S41 K03797 - 3.4.21.102 0.000000000000000000000000000000006594 131.0
TLS2_k127_2614837_1 phosphoribosyltransferase K07100 - - 0.0000000000000000000000002987 108.0
TLS2_k127_2614837_2 translation release factor activity - - - 0.0000000000000000000000004564 118.0
TLS2_k127_2623548_0 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001386 252.0
TLS2_k127_2623548_1 lipolytic protein G-D-S-L family - - - 0.000000000000003077 88.0
TLS2_k127_2630561_0 TonB C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000008826 247.0
TLS2_k127_2630561_1 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000004744 153.0
TLS2_k127_2657669_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 466.0
TLS2_k127_2657669_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 308.0
TLS2_k127_2657669_2 conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000723 288.0
TLS2_k127_2657669_3 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000017 219.0
TLS2_k127_2657669_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000007097 87.0
TLS2_k127_2673926_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 443.0
TLS2_k127_2673926_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 377.0
TLS2_k127_2673926_2 Glycosyl transferase, family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 319.0
TLS2_k127_2673926_3 Pas domain - - - 0.00000000000000000000000000000007831 134.0
TLS2_k127_2673926_4 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000001434 123.0
TLS2_k127_2673926_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000001392 102.0
TLS2_k127_2686206_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004324 288.0
TLS2_k127_2686206_1 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000000000000000000000000000000000000001838 209.0
TLS2_k127_2686206_2 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000005563 139.0
TLS2_k127_2686206_3 RNA recognition motif - - - 0.00000000000000000000000000000002062 129.0
TLS2_k127_2686206_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000001206 115.0
TLS2_k127_2686206_5 Putative zinc-finger - - - 0.00000000000000001132 90.0
TLS2_k127_2702777_0 DNA polymerase X K02347 - - 5.659e-251 785.0
TLS2_k127_2702777_1 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 1.336e-202 645.0
TLS2_k127_2702777_10 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 353.0
TLS2_k127_2702777_11 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 340.0
TLS2_k127_2702777_12 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 326.0
TLS2_k127_2702777_13 PFAM Alpha beta hydrolase K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 309.0
TLS2_k127_2702777_14 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000003153 259.0
TLS2_k127_2702777_15 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002107 266.0
TLS2_k127_2702777_16 alpha-ribazole phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000004488 224.0
TLS2_k127_2702777_17 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000001401 203.0
TLS2_k127_2702777_18 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000802 185.0
TLS2_k127_2702777_19 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000002373 186.0
TLS2_k127_2702777_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 634.0
TLS2_k127_2702777_20 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000000000000000006016 183.0
TLS2_k127_2702777_21 - - - - 0.000000000000000000000000000000000000001986 171.0
TLS2_k127_2702777_22 Calcineurin-like phosphoesterase K14379 - 3.1.3.2 0.0000000000000000000000000000000000001228 154.0
TLS2_k127_2702777_23 - - - - 0.0000000000000000000000000000007836 132.0
TLS2_k127_2702777_24 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000002966 111.0
TLS2_k127_2702777_25 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000012 117.0
TLS2_k127_2702777_26 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000004719 93.0
TLS2_k127_2702777_27 PFAM thioesterase superfamily K02614 - - 0.0000000000000000006868 93.0
TLS2_k127_2702777_28 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.000000000000008507 76.0
TLS2_k127_2702777_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 599.0
TLS2_k127_2702777_30 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000009978 78.0
TLS2_k127_2702777_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 596.0
TLS2_k127_2702777_5 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 563.0
TLS2_k127_2702777_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 536.0
TLS2_k127_2702777_7 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 391.0
TLS2_k127_2702777_8 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 380.0
TLS2_k127_2702777_9 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 361.0
TLS2_k127_2713243_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 398.0
TLS2_k127_2713243_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 380.0
TLS2_k127_2713243_2 repeat-containing protein - - - 0.0000000000000000000000000003058 130.0
TLS2_k127_2713243_3 determination of stomach left/right asymmetry K10407 - - 0.0000000000000000000000007132 119.0
TLS2_k127_2718843_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009764 575.0
TLS2_k127_2718843_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 533.0
TLS2_k127_2718843_2 Cytochrome c - - - 0.00000000000001436 77.0
TLS2_k127_2734280_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 342.0
TLS2_k127_2750556_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 1.027e-301 943.0
TLS2_k127_2750556_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 611.0
TLS2_k127_2750556_10 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000149 137.0
TLS2_k127_2750556_11 - - - - 0.000000000000000000000000000002094 127.0
TLS2_k127_2750556_12 TPM domain K06872 - - 0.0000000000000000000000000354 117.0
TLS2_k127_2750556_13 Hexosyltransferase - - - 0.000000000001044 73.0
TLS2_k127_2750556_2 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 527.0
TLS2_k127_2750556_3 Beta-lactamase class C K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 503.0
TLS2_k127_2750556_4 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 490.0
TLS2_k127_2750556_5 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 435.0
TLS2_k127_2750556_6 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 337.0
TLS2_k127_2750556_7 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 308.0
TLS2_k127_2750556_8 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000002482 245.0
TLS2_k127_2750556_9 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000002813 213.0
TLS2_k127_275455_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 439.0
TLS2_k127_275455_1 Protein of unknown function (DUF1553) - - - 0.0000000000000000000000000000000000002183 149.0
TLS2_k127_2767953_0 PQQ-like domain K00114 - 1.1.2.8 1.62e-217 686.0
TLS2_k127_2767953_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000001343 168.0
TLS2_k127_2767953_4 Putative restriction endonuclease - - - 0.00000000000002245 80.0
TLS2_k127_2773371_0 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 405.0
TLS2_k127_2773371_1 Oxidoreductase - - - 0.0000000000000000000000000001668 119.0
TLS2_k127_2773371_2 Protein of unknown function, DUF481 - - - 0.000000000000000000000009985 104.0
TLS2_k127_2773373_0 PhoD-like phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005418 263.0
TLS2_k127_2773373_1 Protein of unknown function, DUF481 - - - 0.000000000000000000000005308 105.0
TLS2_k127_2786878_0 Carboxypeptidase regulatory-like domain - - - 0.0 1051.0
TLS2_k127_2786878_1 Carboxypeptidase regulatory-like domain - - - 8.699e-258 833.0
TLS2_k127_2786878_10 Domain of unknown function (DUF3883) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008454 283.0
TLS2_k127_2786878_11 extracellular solute-binding protein, family 1 K22003 - 5.3.3.7 0.0000000000000000000000000000000000000000000000000000000000005425 219.0
TLS2_k127_2786878_12 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000000000000000000000000002556 185.0
TLS2_k127_2786878_13 metal-dependent protease of the Pad1 Jab1 superfamily - - - 0.000000000000000000000000000000000000000000000005943 195.0
TLS2_k127_2786878_14 PIN domain - - - 0.00000000000000000000000000000000000000000000001024 175.0
TLS2_k127_2786878_16 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000003847 123.0
TLS2_k127_2786878_17 - K18829 - - 0.00000000000000000000000009721 108.0
TLS2_k127_2786878_18 - K18829 - - 0.000000000000002731 81.0
TLS2_k127_2786878_19 - - - - 0.0000000003645 69.0
TLS2_k127_2786878_2 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 578.0
TLS2_k127_2786878_20 arylsulfatase activity K01138 - - 0.000000008372 64.0
TLS2_k127_2786878_21 Metallo-beta-lactamase superfamily - - - 0.0002152 45.0
TLS2_k127_2786878_3 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 571.0
TLS2_k127_2786878_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 537.0
TLS2_k127_2786878_5 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 500.0
TLS2_k127_2786878_6 carboxylic acid catabolic process K12661 - 4.2.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 497.0
TLS2_k127_2786878_7 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 441.0
TLS2_k127_2786878_8 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 407.0
TLS2_k127_2786878_9 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 373.0
TLS2_k127_2786923_0 Ethanolamine ammonia lyase large subunit K03735 - 4.3.1.7 1.724e-220 691.0
TLS2_k127_2786923_1 Carboxypeptidase regulatory-like domain - - - 7.73e-216 711.0
TLS2_k127_2786923_10 May be involved in cell division K05803 - - 0.000000000000000000000000000000000000000000000000000000003254 211.0
TLS2_k127_2786923_11 - - - - 0.0000000000000000000000000000003511 139.0
TLS2_k127_2786923_12 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.000000000000000000000000005548 113.0
TLS2_k127_2786923_13 Pfam:Arch_ATPase - - - 0.000000000000000000000000009885 114.0
TLS2_k127_2786923_14 - - - - 0.00000000000000000000001853 111.0
TLS2_k127_2786923_15 Plasmid stabilization system K19092 - - 0.000000003279 61.0
TLS2_k127_2786923_16 Tetratricopeptide repeat - - - 0.00001084 56.0
TLS2_k127_2786923_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 6.402e-214 677.0
TLS2_k127_2786923_3 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 540.0
TLS2_k127_2786923_4 FAD dependent oxidoreductase K15736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 529.0
TLS2_k127_2786923_5 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 362.0
TLS2_k127_2786923_6 Belongs to the EutC family K03736 - 4.3.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000002172 263.0
TLS2_k127_2786923_7 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001375 257.0
TLS2_k127_2786923_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001988 240.0
TLS2_k127_2786923_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
TLS2_k127_2814530_0 COG3119 Arylsulfatase A and related enzymes K01135 - 3.1.6.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 465.0
TLS2_k127_2814530_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000003567 81.0
TLS2_k127_2814530_2 protein conserved in bacteria - - - 0.000001018 59.0
TLS2_k127_2817747_0 - - - - 6.306e-310 966.0
TLS2_k127_2817747_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 582.0
TLS2_k127_2817747_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000001426 207.0
TLS2_k127_2817747_11 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000007492 161.0
TLS2_k127_2817747_12 STAS domain K04749 - - 0.0000000000000000000000000000000000000000003369 163.0
TLS2_k127_2817747_13 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000001144 145.0
TLS2_k127_2817747_14 Redoxin - - - 0.0000000000000000000000000000000003306 136.0
TLS2_k127_2817747_15 - - - - 0.000000000000056 82.0
TLS2_k127_2817747_2 RNA polymerase sigma-54 factor K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 580.0
TLS2_k127_2817747_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 557.0
TLS2_k127_2817747_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 463.0
TLS2_k127_2817747_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 458.0
TLS2_k127_2817747_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 456.0
TLS2_k127_2817747_7 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 359.0
TLS2_k127_2817747_8 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 342.0
TLS2_k127_2817747_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001121 252.0
TLS2_k127_2820840_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 609.0
TLS2_k127_2820840_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 311.0
TLS2_k127_2820840_2 PFAM SEC-C motif K09858 - - 0.0000000007154 62.0
TLS2_k127_2822140_0 Cytochrome c - - - 0.0 1113.0
TLS2_k127_2822140_1 arylsulfatase activity - - - 7.238e-222 712.0
TLS2_k127_2822140_2 D-arabinono-1,4-lactone oxidase - - - 2.466e-194 615.0
TLS2_k127_2822140_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 288.0
TLS2_k127_2822140_4 Beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000002453 243.0
TLS2_k127_2822140_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000003689 160.0
TLS2_k127_2822140_6 sequence-specific DNA binding K07726 - - 0.00000000000000000000000603 106.0
TLS2_k127_2822140_7 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.00000004085 55.0
TLS2_k127_2832572_0 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 398.0
TLS2_k127_2832572_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 353.0
TLS2_k127_2832572_10 PFAM Nickel transport complex, NikM subunit, transmembrane - - - 0.00005748 53.0
TLS2_k127_2832572_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000001242 231.0
TLS2_k127_2832572_3 - - - - 0.00000000000000000000000000000000000000000000000006772 196.0
TLS2_k127_2832572_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000001236 144.0
TLS2_k127_2832572_5 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000009651 129.0
TLS2_k127_2832572_6 Cobalt transport protein K02008 - - 0.00000000000000000000000004429 119.0
TLS2_k127_2832572_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000973 105.0
TLS2_k127_2832572_8 transcriptional regulator K03892 - - 0.0000000000000000000002307 100.0
TLS2_k127_2832572_9 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.0000000000000000001184 95.0
TLS2_k127_2837499_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 9.173e-206 647.0
TLS2_k127_2837499_1 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 439.0
TLS2_k127_2837499_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000008277 218.0
TLS2_k127_2837499_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000001406 192.0
TLS2_k127_2842269_0 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 482.0
TLS2_k127_2842269_1 protocatechuate 3,4-dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 409.0
TLS2_k127_2842269_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005187 277.0
TLS2_k127_2845393_0 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 298.0
TLS2_k127_2845393_1 - - - - 0.000000000000000000001731 102.0
TLS2_k127_284565_0 protein conserved in bacteria - - - 1.341e-246 779.0
TLS2_k127_284565_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 501.0
TLS2_k127_284565_10 - - - - 0.0000000000000000005449 93.0
TLS2_k127_284565_11 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000003852 65.0
TLS2_k127_284565_2 ATPase with chaperone activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 485.0
TLS2_k127_284565_3 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 417.0
TLS2_k127_284565_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 329.0
TLS2_k127_284565_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 302.0
TLS2_k127_284565_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004517 231.0
TLS2_k127_284565_7 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000004335 196.0
TLS2_k127_284565_8 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000003705 114.0
TLS2_k127_284565_9 heme binding - - - 0.00000000000000000000000003108 119.0
TLS2_k127_2849205_0 Has an organic peroxide-dependent peroxidase activity K03781 - 1.11.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 462.0
TLS2_k127_2849205_1 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 445.0
TLS2_k127_2849205_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000005191 268.0
TLS2_k127_2849205_3 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000004473 161.0
TLS2_k127_2849205_4 amidohydrolase - - - 0.00000000000009479 77.0
TLS2_k127_285119_0 Carboxypeptidase regulatory-like domain - - - 0.0 1473.0
TLS2_k127_285119_1 Cytochrome c - - - 0.0 1184.0
TLS2_k127_285119_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 344.0
TLS2_k127_285119_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 300.0
TLS2_k127_285119_12 Belongs to the ABC transporter superfamily K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006483 270.0
TLS2_k127_285119_13 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001588 268.0
TLS2_k127_285119_14 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001073 254.0
TLS2_k127_285119_15 COG1312 D-mannonate dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002551 251.0
TLS2_k127_285119_16 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000002766 247.0
TLS2_k127_285119_17 ABC transporter, permease protein K02053,K11070 - - 0.0000000000000000000000000000000000000000000000000000000000248 220.0
TLS2_k127_285119_18 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000001112 233.0
TLS2_k127_285119_19 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000001451 198.0
TLS2_k127_285119_2 Protein of unknown function (DUF1501) - - - 3.581e-259 807.0
TLS2_k127_285119_20 HD domain K07814 - - 0.000000000000000000000000000000000008634 140.0
TLS2_k127_285119_21 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000002334 136.0
TLS2_k127_285119_22 MgtC SapB transporter K07507 - - 0.00000000000000000000000000002343 125.0
TLS2_k127_285119_23 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000004757 131.0
TLS2_k127_285119_24 Xylose isomerase - - - 0.00000000000000000000000000007569 123.0
TLS2_k127_285119_25 ABC-type spermidine putrescine transport system, permease component I K11075 - - 0.000000000000000001107 97.0
TLS2_k127_285119_26 BON domain - - - 0.000000000000002438 83.0
TLS2_k127_285119_27 Protein of unknown function (DUF1328) - - - 0.0000000000000168 76.0
TLS2_k127_285119_28 Spermidine putrescine-binding periplasmic protein K11069 - - 0.0000000000001267 84.0
TLS2_k127_285119_29 - - - - 0.0000000000005491 74.0
TLS2_k127_285119_3 transport - - - 5.35e-254 820.0
TLS2_k127_285119_31 Transcriptional regulator - - - 0.0000000036 62.0
TLS2_k127_285119_32 PFAM CBS domain containing protein - - - 0.00005234 55.0
TLS2_k127_285119_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 519.0
TLS2_k127_285119_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 490.0
TLS2_k127_285119_6 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 421.0
TLS2_k127_285119_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 412.0
TLS2_k127_285119_8 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 408.0
TLS2_k127_285119_9 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 331.0
TLS2_k127_2861230_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 575.0
TLS2_k127_2861230_1 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000002018 186.0
TLS2_k127_2871162_0 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 301.0
TLS2_k127_2871162_1 Metallo-peptidase family M12B Reprolysin-like - - - 0.00000000002526 72.0
TLS2_k127_2871162_2 response regulator, receiver K02479 - - 0.000009026 49.0
TLS2_k127_287334_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.46e-248 777.0
TLS2_k127_287334_1 PFAM Sulfatase - - - 3.462e-222 699.0
TLS2_k127_287334_10 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 297.0
TLS2_k127_287334_11 PFAM cytochrome c oxidase, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001285 280.0
TLS2_k127_287334_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000008928 258.0
TLS2_k127_287334_13 4-amino-4-deoxy-L-arabinose transferase activity K16648 - - 0.000000000000000000000000000000000000000000000000000000000006658 216.0
TLS2_k127_287334_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000158 198.0
TLS2_k127_287334_15 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000007838 192.0
TLS2_k127_287334_16 Beta-lactamase - - - 0.0000000000000000000000000000000000007223 156.0
TLS2_k127_287334_17 - - - - 0.0000000000000000000000002136 111.0
TLS2_k127_287334_18 - - - - 0.0000000000000000000000009728 111.0
TLS2_k127_287334_19 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000000000003581 93.0
TLS2_k127_287334_2 myo-inosose-2 dehydratase activity K06606 - 5.3.99.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 548.0
TLS2_k127_287334_20 PFAM Polysulphide reductase, NrfD - - - 0.0000000000001222 72.0
TLS2_k127_287334_21 Protein of unknown function (DUF2283) - - - 0.00000000002302 74.0
TLS2_k127_287334_22 - - - - 0.000001926 59.0
TLS2_k127_287334_3 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 499.0
TLS2_k127_287334_4 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 430.0
TLS2_k127_287334_5 PFAM Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 418.0
TLS2_k127_287334_6 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 402.0
TLS2_k127_287334_7 PFAM penicillin-binding protein transpeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 390.0
TLS2_k127_287334_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 372.0
TLS2_k127_287334_9 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 345.0
TLS2_k127_2875453_0 TonB-dependent receptor - - - 0.0 1874.0
TLS2_k127_2875453_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1364.0
TLS2_k127_2875453_2 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 441.0
TLS2_k127_2875453_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008099 269.0
TLS2_k127_2875453_6 CHAP domain - - - 0.0000000000000000000000000000000007039 140.0
TLS2_k127_2875453_7 RES - - - 0.0000000001006 73.0
TLS2_k127_2883900_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 453.0
TLS2_k127_2883900_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 365.0
TLS2_k127_2883900_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000002894 266.0
TLS2_k127_2883900_3 PFAM Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001789 280.0
TLS2_k127_2883900_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000003152 223.0
TLS2_k127_2883900_5 Lipopolysaccharide-assembly - - - 0.00000000000000000000000000000000000000001632 169.0
TLS2_k127_2883900_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000002733 149.0
TLS2_k127_2883900_7 - - - - 0.0000000000000000000001162 103.0
TLS2_k127_2883900_8 nucleic acid-templated transcription K18843 - - 0.00000000007033 68.0
TLS2_k127_2883900_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000005603 58.0
TLS2_k127_288823_0 Nacht domain - - - 0.0 1223.0
TLS2_k127_288823_1 CoA-binding K09181 - - 0.0 1121.0
TLS2_k127_288823_10 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 452.0
TLS2_k127_288823_11 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 449.0
TLS2_k127_288823_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 436.0
TLS2_k127_288823_13 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 413.0
TLS2_k127_288823_14 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 393.0
TLS2_k127_288823_15 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 363.0
TLS2_k127_288823_16 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 353.0
TLS2_k127_288823_17 Metallo-peptidase family M12B Reprolysin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 366.0
TLS2_k127_288823_18 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 339.0
TLS2_k127_288823_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 328.0
TLS2_k127_288823_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.034e-230 723.0
TLS2_k127_288823_20 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 328.0
TLS2_k127_288823_21 Signal Transduction Histidine Kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 338.0
TLS2_k127_288823_22 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 289.0
TLS2_k127_288823_23 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006916 281.0
TLS2_k127_288823_24 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001044 282.0
TLS2_k127_288823_25 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001548 275.0
TLS2_k127_288823_26 mannonate dehydratase activity K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000269 271.0
TLS2_k127_288823_27 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001856 272.0
TLS2_k127_288823_28 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002991 248.0
TLS2_k127_288823_29 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000703 246.0
TLS2_k127_288823_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 2.27e-205 660.0
TLS2_k127_288823_30 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002248 261.0
TLS2_k127_288823_31 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004014 244.0
TLS2_k127_288823_32 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000001057 238.0
TLS2_k127_288823_33 Glyoxalase-like domain K07032 - - 0.00000000000000000000000000000000000000000000000000000000000000007971 225.0
TLS2_k127_288823_34 NAD binding K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000001786 243.0
TLS2_k127_288823_35 response regulator K02479,K07684,K07685 - - 0.000000000000000000000000000000000000000000000000000000000002598 217.0
TLS2_k127_288823_36 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000001396 216.0
TLS2_k127_288823_37 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000006986 203.0
TLS2_k127_288823_38 Conserved repeat domain - - - 0.000000000000000000000000000000000000000000000000000008467 211.0
TLS2_k127_288823_39 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000002191 201.0
TLS2_k127_288823_4 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 585.0
TLS2_k127_288823_40 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000005972 182.0
TLS2_k127_288823_41 Histidine kinase - - - 0.000000000000000000000000000000000000000000000003089 195.0
TLS2_k127_288823_42 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000003269 179.0
TLS2_k127_288823_43 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000002839 174.0
TLS2_k127_288823_44 PFAM Redoxin - - - 0.000000000000000000000000000000000000000003689 160.0
TLS2_k127_288823_45 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000006826 167.0
TLS2_k127_288823_46 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000003542 142.0
TLS2_k127_288823_47 Rnk N-terminus K06140 - - 0.00000000000000000000000000000000003916 140.0
TLS2_k127_288823_49 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000001302 119.0
TLS2_k127_288823_5 tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 560.0
TLS2_k127_288823_50 Stress responsive A/B Barrel Domain - - - 0.000000000000000000000000003513 117.0
TLS2_k127_288823_51 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000375 117.0
TLS2_k127_288823_52 - - - - 0.0000000000000000000000000498 112.0
TLS2_k127_288823_53 - - - - 0.000000000000000000000006083 107.0
TLS2_k127_288823_54 Protein of unknown function (DUF433) - - - 0.0000000000000000000006496 96.0
TLS2_k127_288823_55 Universal stress protein - - - 0.0000000000000000002766 100.0
TLS2_k127_288823_56 NAD-dependent epimerase dehydratase - - - 0.000000000000000226 87.0
TLS2_k127_288823_57 Transcriptional regulator - - - 0.000000000000001446 78.0
TLS2_k127_288823_58 Response regulator, receiver - - - 0.000000000000004369 81.0
TLS2_k127_288823_59 Sulfurtransferase - - - 0.000000000002267 73.0
TLS2_k127_288823_6 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 512.0
TLS2_k127_288823_60 Tetratricopeptide repeat - - - 0.00000000007214 74.0
TLS2_k127_288823_61 Transcriptional regulator - - - 0.000000000518 68.0
TLS2_k127_288823_62 Bacterial transcription activator, effector binding domain - - - 0.0000004142 59.0
TLS2_k127_288823_7 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 481.0
TLS2_k127_288823_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 469.0
TLS2_k127_288823_9 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 466.0
TLS2_k127_2889449_0 COG0474 Cation transport ATPase - - - 0.0 1264.0
TLS2_k127_2889449_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 310.0
TLS2_k127_2889449_2 Alpha/beta-hydrolase family - - - 0.00000000000000000000000000000006552 128.0
TLS2_k127_2891279_0 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 518.0
TLS2_k127_2891279_1 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 343.0
TLS2_k127_2891279_2 Belongs to the UPF0403 family - - - 0.000000000000000000000000000000000000000000000004551 175.0
TLS2_k127_2891279_4 Esterase PHB depolymerase - - - 0.00005644 45.0
TLS2_k127_2895760_0 Carbamoyltransferase C-terminus K00612 - - 4.159e-214 679.0
TLS2_k127_2895760_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 520.0
TLS2_k127_2895760_2 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002792 260.0
TLS2_k127_2902303_0 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 488.0
TLS2_k127_2902303_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 433.0
TLS2_k127_2902303_2 Bacterial type II and III secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 337.0
TLS2_k127_2902303_3 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 318.0
TLS2_k127_2902303_4 carbohydrate binding K13688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 291.0
TLS2_k127_2902303_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000002192 272.0
TLS2_k127_2902303_6 PFAM Rieske 2Fe-2S K00363 - 1.7.1.15 0.00000000000000000000000001154 112.0
TLS2_k127_2909237_0 Carboxypeptidase regulatory-like domain - - - 1.246e-221 725.0
TLS2_k127_2909237_1 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 550.0
TLS2_k127_2909237_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000002378 89.0
TLS2_k127_2909237_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 396.0
TLS2_k127_2909237_3 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 373.0
TLS2_k127_2909237_4 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 310.0
TLS2_k127_2909237_5 Penicillin binding protein transpeptidase domain - - - 0.0000000000000000000000000000000000000000000000000001152 196.0
TLS2_k127_2909237_6 protein conserved in bacteria K04750 - - 0.000000000000000000000000000000000000000000007755 166.0
TLS2_k127_2909237_7 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000994 133.0
TLS2_k127_2909237_8 ACT domain - - - 0.00000000000000000000000000004403 125.0
TLS2_k127_2909237_9 lactoylglutathione lyase activity - - - 0.000000000000000000001502 99.0
TLS2_k127_291483_0 Membrane-bound dehydrogenase domain - - - 1.078e-231 751.0
TLS2_k127_291483_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 331.0
TLS2_k127_291483_2 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002825 268.0
TLS2_k127_291483_3 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000001148 216.0
TLS2_k127_291483_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000304 139.0
TLS2_k127_291483_5 Methyltransferase domain - - - 0.00000000000000000000000000002421 130.0
TLS2_k127_2919256_0 CBD_II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 312.0
TLS2_k127_292007_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 286.0
TLS2_k127_292007_1 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002838 274.0
TLS2_k127_292007_2 - - - - 0.00000004289 63.0
TLS2_k127_2942566_0 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 262.0
TLS2_k127_2942566_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000442 238.0
TLS2_k127_2942566_2 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.000005387 54.0
TLS2_k127_2948759_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001324 274.0
TLS2_k127_2948759_1 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000000000000000000000000001165 178.0
TLS2_k127_2948759_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000129 183.0
TLS2_k127_2948759_3 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286 - 3.4.16.4 0.000000000000000000000000000000000000709 151.0
TLS2_k127_2973868_0 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 600.0
TLS2_k127_2973868_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 587.0
TLS2_k127_2973868_2 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 483.0
TLS2_k127_2973868_3 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 374.0
TLS2_k127_2973886_0 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005233 243.0
TLS2_k127_2973886_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000002893 66.0
TLS2_k127_2986285_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 527.0
TLS2_k127_2986285_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000446 154.0
TLS2_k127_2986285_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000002831 53.0
TLS2_k127_2986285_3 Belongs to the peptidase S8 family - - - 0.000004995 55.0
TLS2_k127_299331_0 Carboxypeptidase regulatory-like domain - - - 1.554e-313 993.0
TLS2_k127_299331_1 - - - - 8.301e-204 655.0
TLS2_k127_299331_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000008163 237.0
TLS2_k127_299331_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000002551 232.0
TLS2_k127_299331_4 cellulose binding - - - 0.0000000000000000000000000000000000000000001539 181.0
TLS2_k127_299331_5 NmrA-like family - - - 0.0000000000000000000000000000000004105 138.0
TLS2_k127_299331_6 Caspase domain - - - 0.000000000000000000001153 111.0
TLS2_k127_3001304_0 protocatechuate 3,4-dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 421.0
TLS2_k127_3001304_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 334.0
TLS2_k127_3001304_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000004566 86.0
TLS2_k127_300184_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1077.0
TLS2_k127_300184_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 516.0
TLS2_k127_300184_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 445.0
TLS2_k127_300184_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001562 249.0
TLS2_k127_300184_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000004002 226.0
TLS2_k127_3007765_0 sucrose synthase K00695 - 2.4.1.13 0.0 1043.0
TLS2_k127_3007765_1 Sucrose phosphate synthase, sucrose phosphatase-like K00696 - 2.4.1.14 3.434e-207 659.0
TLS2_k127_3007765_2 arylsulfatase activity K01137,K01138 - 3.1.6.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 559.0
TLS2_k127_3007765_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 504.0
TLS2_k127_3007765_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 409.0
TLS2_k127_3007765_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 332.0
TLS2_k127_3007765_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000004204 269.0
TLS2_k127_3014884_0 Uroporphyrin-III C-methyltransferase K02303,K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000003773 258.0
TLS2_k127_3014884_1 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000009378 161.0
TLS2_k127_3014884_2 gluconolactonase activity K07004,K14274 - - 0.0000000000000000000000000000000000000127 162.0
TLS2_k127_3025133_0 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 464.0
TLS2_k127_3025133_1 Ferrous iron transport protein B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 368.0
TLS2_k127_3025133_2 Ferrous iron transport protein B C terminus K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 323.0
TLS2_k127_3025133_3 iron ion homeostasis K03322,K03709,K04758 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005869 255.0
TLS2_k127_3025133_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000005339 154.0
TLS2_k127_3025133_5 - - - - 0.0001465 48.0
TLS2_k127_3025982_0 TonB-dependent Receptor Plug Domain - - - 9.097e-239 762.0
TLS2_k127_3025982_1 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 407.0
TLS2_k127_3025982_2 PFAM Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 349.0
TLS2_k127_3025982_3 - - - - 0.0000000000000000000000000000000000000006388 152.0
TLS2_k127_3025982_4 - - - - 0.00000000000007882 76.0
TLS2_k127_306397_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 548.0
TLS2_k127_306397_1 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 489.0
TLS2_k127_306397_10 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000001031 85.0
TLS2_k127_306397_11 PEP-CTERM motif - - - 0.00000000000005851 80.0
TLS2_k127_306397_12 PEP-CTERM motif - - - 0.0009521 49.0
TLS2_k127_306397_2 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 462.0
TLS2_k127_306397_3 membrane K07148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 390.0
TLS2_k127_306397_4 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 369.0
TLS2_k127_306397_5 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 328.0
TLS2_k127_306397_7 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007497 284.0
TLS2_k127_306397_8 alginic acid biosynthetic process K01729 - 4.2.2.3 0.0000000000000000000000000000000000000000000000000009131 184.0
TLS2_k127_306397_9 Sulfatase - - - 0.0000000000000000000000000000000000000000000000001951 193.0
TLS2_k127_3065375_0 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 393.0
TLS2_k127_3065375_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000002849 214.0
TLS2_k127_3065375_10 Transposase DDE domain - - - 0.0000000000000000000000377 106.0
TLS2_k127_3065375_11 PFAM transposase IS4 family protein - - - 0.0000000000000000005785 95.0
TLS2_k127_3065375_13 self proteolysis K11021 - - 0.00000000002262 70.0
TLS2_k127_3065375_14 - - - - 0.00002531 53.0
TLS2_k127_3065375_2 permease - - - 0.0000000000000000000000000000000000000000000000000000001624 209.0
TLS2_k127_3065375_3 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000005023 160.0
TLS2_k127_3065375_4 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000000000000000000000000005338 145.0
TLS2_k127_3065375_5 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000000000000000007976 141.0
TLS2_k127_3065375_6 ethanolamine catabolic process K04027 - - 0.0000000000000000000000000000000001985 133.0
TLS2_k127_3065375_7 Adenylate cyclase - - - 0.000000000000000000000000000000002 140.0
TLS2_k127_3065375_8 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000000000000001295 124.0
TLS2_k127_3065375_9 DNA-templated transcription, termination K03628 - - 0.00000000000000000000000000261 117.0
TLS2_k127_307209_0 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 543.0
TLS2_k127_307209_1 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 406.0
TLS2_k127_307209_2 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 367.0
TLS2_k127_307209_3 - - - - 0.00000000000008012 83.0
TLS2_k127_307209_6 self proteolysis K01406 - 3.4.24.40 0.0007487 45.0
TLS2_k127_3084994_0 protocatechuate 3,4-dioxygenase activity - - - 8.62e-309 966.0
TLS2_k127_3084994_1 Cytochrome c - - - 6.632e-252 807.0
TLS2_k127_3084994_2 Alpha-L-fucosidase K01206 - 3.2.1.51 4.216e-209 663.0
TLS2_k127_3084994_3 Protein of unknown function (DUF1501) - - - 2.151e-196 623.0
TLS2_k127_3084994_4 Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 419.0
TLS2_k127_3084994_5 Thermolysin metallopeptidase, alpha-helical domain K01400 - 3.4.24.28 0.000000000000000000000074 102.0
TLS2_k127_3084994_6 FCD - - - 0.0000000000000000000001375 106.0
TLS2_k127_3094732_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 3.159e-234 774.0
TLS2_k127_3094732_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 2.168e-222 709.0
TLS2_k127_3094732_10 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 290.0
TLS2_k127_3094732_11 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 287.0
TLS2_k127_3094732_12 Carbon-nitrogen hydrolase K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000001996 231.0
TLS2_k127_3094732_13 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000000000000000000000000000002444 152.0
TLS2_k127_3094732_14 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000000000000000000009367 150.0
TLS2_k127_3094732_15 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000005027 150.0
TLS2_k127_3094732_16 Domain of unknown function (DUF4870) - - - 0.0000000000000000000000000004331 119.0
TLS2_k127_3094732_17 PFAM Major facilitator superfamily - - - 0.000000000000000000000008783 108.0
TLS2_k127_3094732_18 sequence-specific DNA binding K15539 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00000000000003624 77.0
TLS2_k127_3094732_19 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000003169 69.0
TLS2_k127_3094732_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.052e-221 696.0
TLS2_k127_3094732_3 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 533.0
TLS2_k127_3094732_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 472.0
TLS2_k127_3094732_5 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 443.0
TLS2_k127_3094732_6 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 351.0
TLS2_k127_3094732_7 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 344.0
TLS2_k127_3094732_8 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 295.0
TLS2_k127_3094732_9 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 298.0
TLS2_k127_3107568_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 335.0
TLS2_k127_3107568_1 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000263 239.0
TLS2_k127_3107568_2 Transposase - - - 0.00000000000003127 76.0
TLS2_k127_3107568_3 Transposase - - - 0.000000000003997 70.0
TLS2_k127_3107568_4 COG3385 FOG Transposase and inactivated derivatives - - - 0.0000006085 55.0
TLS2_k127_3107568_5 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0003691 48.0
TLS2_k127_3112738_0 Glycogen debranching enzyme - - - 1.934e-258 814.0
TLS2_k127_3112738_1 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 516.0
TLS2_k127_3112738_10 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 296.0
TLS2_k127_3112738_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000001726 222.0
TLS2_k127_3112738_12 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000001294 215.0
TLS2_k127_3112738_13 FCD - - - 0.00000000000000000000000000000000000000000000000000000000008704 211.0
TLS2_k127_3112738_14 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000000000000000000000043 206.0
TLS2_k127_3112738_15 AntiSigma factor - - - 0.000000000000000000000000000000000000000007346 165.0
TLS2_k127_3112738_16 FCD - - - 0.000000000000000000000000000000002198 139.0
TLS2_k127_3112738_17 PfkB domain protein - - - 0.0002177 44.0
TLS2_k127_3112738_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 525.0
TLS2_k127_3112738_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 494.0
TLS2_k127_3112738_4 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 407.0
TLS2_k127_3112738_5 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 371.0
TLS2_k127_3112738_6 tRNA processing K04075,K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 364.0
TLS2_k127_3112738_7 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 354.0
TLS2_k127_3112738_8 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 345.0
TLS2_k127_3112738_9 PFAM secretion protein HlyD family protein K02005,K16922 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 305.0
TLS2_k127_3113167_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.447e-287 888.0
TLS2_k127_3113167_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 612.0
TLS2_k127_3113167_10 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 329.0
TLS2_k127_3113167_11 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 325.0
TLS2_k127_3113167_12 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 298.0
TLS2_k127_3113167_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000126 255.0
TLS2_k127_3113167_14 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001095 229.0
TLS2_k127_3113167_15 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000402 200.0
TLS2_k127_3113167_16 PFAM secretion protein HlyD - - - 0.0000000000000000000000000000000000000000000000001727 187.0
TLS2_k127_3113167_17 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000006047 146.0
TLS2_k127_3113167_18 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000001307 144.0
TLS2_k127_3113167_2 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 511.0
TLS2_k127_3113167_20 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000002237 126.0
TLS2_k127_3113167_22 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000004031 88.0
TLS2_k127_3113167_24 Tetratricopeptide repeat - - - 0.00001668 51.0
TLS2_k127_3113167_3 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 481.0
TLS2_k127_3113167_4 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 472.0
TLS2_k127_3113167_5 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 436.0
TLS2_k127_3113167_6 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 435.0
TLS2_k127_3113167_7 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 424.0
TLS2_k127_3113167_8 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 394.0
TLS2_k127_3113167_9 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 353.0
TLS2_k127_3113271_0 methyltransferase activity K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 431.0
TLS2_k127_3113271_1 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 400.0
TLS2_k127_3113271_2 Ureide permease K05340 - - 0.000000000000000000000000000000000000000000000000000000000000002037 231.0
TLS2_k127_3113271_3 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000003973 130.0
TLS2_k127_3113271_4 Asp Glu hydantoin racemase - - - 0.000000000000000000003869 96.0
TLS2_k127_313412_0 Alpha-2-Macroglobulin K06894 - - 7.902e-229 738.0
TLS2_k127_313412_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 541.0
TLS2_k127_313412_2 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 329.0
TLS2_k127_3144486_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 0.0 1387.0
TLS2_k127_3144486_1 ATPase activity K06883 - - 2.546e-304 949.0
TLS2_k127_3144486_11 Glycosyl transferase 4-like - - - 0.0000957 46.0
TLS2_k127_3144486_2 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 496.0
TLS2_k127_3144486_3 Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 418.0
TLS2_k127_3144486_4 SEC-C Motif Domain Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 301.0
TLS2_k127_3144486_5 TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009931 283.0
TLS2_k127_3144486_6 COGs COG0783 DNA-binding ferritin-like protein (oxidative damage protectant) K04047 - - 0.000000000000000000000000000000000000000001434 161.0
TLS2_k127_3144486_7 Alpha beta hydrolase fold-3 domain protein - - - 0.0000000000000000000000000000000000005436 144.0
TLS2_k127_3144486_8 - - - - 0.000000000000000000000000000000000006436 153.0
TLS2_k127_3144486_9 PIN domain - - - 0.00000000000000697 79.0
TLS2_k127_3150236_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000006527 187.0
TLS2_k127_3150236_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000001524 160.0
TLS2_k127_3150236_2 PFAM TPR repeat-containing protein - - - 0.00000000000000000000001189 112.0
TLS2_k127_3150236_3 Adenylate cyclase - - - 0.0000000000000000000001657 108.0
TLS2_k127_3150236_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000002777 80.0
TLS2_k127_3150236_5 PFAM TPR repeat-containing protein - - - 0.000000000001457 78.0
TLS2_k127_317141_0 PQQ-like domain K00114 - 1.1.2.8 8.354e-240 749.0
TLS2_k127_317141_1 PFAM Beta-propeller repeat - - - 0.0000000000000009267 91.0
TLS2_k127_317141_2 cellulose binding - - - 0.0000000000273 77.0
TLS2_k127_3191002_0 transport - - - 2.895e-290 927.0
TLS2_k127_3191002_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.737e-283 880.0
TLS2_k127_3191002_2 photosynthesis K02656 - - 0.0000000000000000000000002337 111.0
TLS2_k127_3191002_3 Dodecin K09165 - - 0.00000000000000000000004209 100.0
TLS2_k127_3196441_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1151.0
TLS2_k127_3196441_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.000000000000000000000000000000000000000000000000000000000000000000001089 256.0
TLS2_k127_3196441_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000006666 167.0
TLS2_k127_3196441_3 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000005453 141.0
TLS2_k127_3196441_4 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.00002812 46.0
TLS2_k127_3204138_0 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 434.0
TLS2_k127_3204138_1 COG2610 H gluconate symporter and related permeases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 434.0
TLS2_k127_3204138_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 413.0
TLS2_k127_3204138_3 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 409.0
TLS2_k127_3204138_4 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 349.0
TLS2_k127_3204138_5 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009774 263.0
TLS2_k127_3204138_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000008359 152.0
TLS2_k127_3204138_7 PFAM Cna B domain protein - - - 0.00000000000000000000000000000000000004049 149.0
TLS2_k127_3231989_0 Carboxypeptidase regulatory-like domain - - - 3.852e-243 769.0
TLS2_k127_3231989_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.478e-225 721.0
TLS2_k127_3231989_2 acetyltransferase K03830 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 344.0
TLS2_k127_3231989_3 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 337.0
TLS2_k127_3232376_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.87e-213 672.0
TLS2_k127_3232376_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 539.0
TLS2_k127_3232376_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 501.0
TLS2_k127_3232376_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 469.0
TLS2_k127_3232376_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 404.0
TLS2_k127_3232376_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 358.0
TLS2_k127_3232376_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 325.0
TLS2_k127_3232376_7 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 323.0
TLS2_k127_3232376_8 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000005773 225.0
TLS2_k127_3232376_9 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000003794 175.0
TLS2_k127_3238773_0 cell wall glycoprotein biosynthetic process - - - 8.029e-205 656.0
TLS2_k127_3238773_1 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 421.0
TLS2_k127_3238773_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 324.0
TLS2_k127_3271927_0 COG3119 Arylsulfatase A K01138 - - 4.223e-248 779.0
TLS2_k127_3271927_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 595.0
TLS2_k127_3271927_10 - - - - 0.00000000000000000000002229 103.0
TLS2_k127_3271927_2 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 452.0
TLS2_k127_3271927_3 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 376.0
TLS2_k127_3271927_4 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 314.0
TLS2_k127_3271927_5 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 299.0
TLS2_k127_3271927_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000003732 182.0
TLS2_k127_3271927_7 - - - - 0.00000000000000000000000000000000000001585 151.0
TLS2_k127_3271927_8 Uncharacterized ACR, COG1430 - - - 0.000000000000000000000000000000000001679 144.0
TLS2_k127_3271927_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000348 133.0
TLS2_k127_327385_0 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 555.0
TLS2_k127_327385_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000008663 192.0
TLS2_k127_327385_2 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000002662 139.0
TLS2_k127_3297619_0 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 411.0
TLS2_k127_3297619_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000242 216.0
TLS2_k127_3297619_2 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000001567 183.0
TLS2_k127_3297619_4 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00006978 55.0
TLS2_k127_3332723_0 Amidohydrolase family - - - 8.786e-250 783.0
TLS2_k127_3332723_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000005251 85.0
TLS2_k127_3340470_0 Alpha-2-Macroglobulin K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 533.0
TLS2_k127_335041_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 6.599e-259 807.0
TLS2_k127_335041_1 Carboxypeptidase regulatory-like domain - - - 5.761e-221 725.0
TLS2_k127_335041_10 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
TLS2_k127_335041_12 general secretion pathway protein K02246,K02456,K02458 - - 0.0000000000000000000000000000000000000000000000000000155 193.0
TLS2_k127_335041_13 FMN binding - - - 0.0000000000000000000000000000000000000000003112 164.0
TLS2_k127_335041_14 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000000000000004445 160.0
TLS2_k127_335041_15 general secretion pathway protein K02456,K02458,K02459,K10927 - - 0.000000000000000000000000000000003533 134.0
TLS2_k127_335041_2 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 510.0
TLS2_k127_335041_20 Tetratricopeptide repeat - - - 0.0000000001723 73.0
TLS2_k127_335041_3 acetylesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 412.0
TLS2_k127_335041_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 349.0
TLS2_k127_335041_5 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 322.0
TLS2_k127_335041_6 Pilus assembly protein K02461,K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 323.0
TLS2_k127_335041_7 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008493 273.0
TLS2_k127_335041_8 protein secretion K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005355 257.0
TLS2_k127_335041_9 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003954 245.0
TLS2_k127_3356837_0 efflux transmembrane transporter activity K02004 - - 2.149e-233 749.0
TLS2_k127_3356837_1 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 6.227e-229 732.0
TLS2_k127_3356837_10 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000003866 102.0
TLS2_k127_3356837_11 - - - - 0.00000000002526 72.0
TLS2_k127_3356837_13 - - - - 0.00000635 55.0
TLS2_k127_3356837_14 PFAM glycosyl transferase family 9 K02841 - - 0.0001894 49.0
TLS2_k127_3356837_2 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 428.0
TLS2_k127_3356837_3 Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 380.0
TLS2_k127_3356837_4 spheroidene biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 379.0
TLS2_k127_3356837_5 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 350.0
TLS2_k127_3356837_6 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 363.0
TLS2_k127_3356837_7 TIGRFAM Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 296.0
TLS2_k127_3356837_8 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002317 268.0
TLS2_k127_3356837_9 Conserved repeat domain - - - 0.00000000000000000000000000000000000000000000000000000001854 219.0
TLS2_k127_3382905_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 9.261e-296 914.0
TLS2_k127_3382905_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 436.0
TLS2_k127_3382905_2 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 319.0
TLS2_k127_3382905_3 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 282.0
TLS2_k127_3382905_4 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000222 217.0
TLS2_k127_3382905_5 - - - - 0.0000000000000000001253 99.0
TLS2_k127_3385858_0 transmembrane transporter activity K03535,K08194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 519.0
TLS2_k127_3385858_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 341.0
TLS2_k127_3385858_2 self proteolysis K01406 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000002339 202.0
TLS2_k127_3398668_0 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 634.0
TLS2_k127_3398668_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 570.0
TLS2_k127_3398668_10 tRNA methyltransferase complex GCD14 subunit - - - 0.000000000000000000000000000003405 132.0
TLS2_k127_3398668_11 - - - - 0.00000000000000000000000001597 113.0
TLS2_k127_3398668_12 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000003698 110.0
TLS2_k127_3398668_13 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000002445 77.0
TLS2_k127_3398668_14 N-Acetylmuramoyl-L-alanine amidase - - - 0.000000007628 65.0
TLS2_k127_3398668_15 Pregnancy-associated plasma protein-A - - - 0.0003331 51.0
TLS2_k127_3398668_2 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 544.0
TLS2_k127_3398668_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 512.0
TLS2_k127_3398668_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 441.0
TLS2_k127_3398668_5 COGs COG0673 dehydrogenase and related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 394.0
TLS2_k127_3398668_6 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 378.0
TLS2_k127_3398668_7 protein kinase activity K13582,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000002514 267.0
TLS2_k127_3398668_8 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000001983 196.0
TLS2_k127_3398668_9 response to abiotic stimulus K06867 - - 0.00000000000000000000000000000000007408 152.0
TLS2_k127_3407560_0 PFAM peptidase - - - 3.653e-201 635.0
TLS2_k127_3407560_1 virulence factor MVIN family protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 460.0
TLS2_k127_3407560_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 309.0
TLS2_k127_3407560_3 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008853,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 293.0
TLS2_k127_3407560_4 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000017 244.0
TLS2_k127_3410869_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000004192 184.0
TLS2_k127_3410869_2 - - - - 0.00000000000000000000000000000000000000000000002821 181.0
TLS2_k127_3454409_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000318 257.0
TLS2_k127_3454409_1 Zn_pept - - - 0.0000000000000000007848 86.0
TLS2_k127_3461124_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 521.0
TLS2_k127_3461124_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000009198 220.0
TLS2_k127_3471729_0 TonB-dependent receptor - - - 2.453e-275 869.0
TLS2_k127_3471729_1 addiction module antidote protein, CC2985 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006071 282.0
TLS2_k127_3471729_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000003692 57.0
TLS2_k127_3472129_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 428.0
TLS2_k127_3472129_1 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 374.0
TLS2_k127_3472129_2 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 287.0
TLS2_k127_3472129_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000003183 226.0
TLS2_k127_3472129_4 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000528 197.0
TLS2_k127_3485442_0 transport - - - 5.76e-205 665.0
TLS2_k127_3507036_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 2.246e-257 817.0
TLS2_k127_3507036_1 Carboxypeptidase regulatory-like domain - - - 3.715e-200 654.0
TLS2_k127_3507036_2 BNR repeat-like domain K05989 - 3.2.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 401.0
TLS2_k127_3507036_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 323.0
TLS2_k127_3507036_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000000002397 175.0
TLS2_k127_3507036_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000009212 156.0
TLS2_k127_3507036_6 Cbs domain - - - 0.00000000000000000000000000000000032 135.0
TLS2_k127_3514108_0 Fungal family of unknown function (DUF1776) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 388.0
TLS2_k127_3514108_1 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000006005 228.0
TLS2_k127_3514108_2 Cytochrome c - - - 0.000000000000000000000000000000000000000003913 164.0
TLS2_k127_3514108_3 PQQ-like domain K00114 - 1.1.2.8 0.0000004084 53.0
TLS2_k127_352836_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 5e-323 1000.0
TLS2_k127_352836_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.747e-238 749.0
TLS2_k127_352836_10 - - - - 0.00000006405 61.0
TLS2_k127_352836_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 524.0
TLS2_k127_352836_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 352.0
TLS2_k127_352836_4 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 308.0
TLS2_k127_352836_5 metallophosphoesterase K07096,K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004699 266.0
TLS2_k127_352836_6 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000000000000000000000000000000000001335 192.0
TLS2_k127_352836_7 Transposase DDE domain - - - 0.000000000000000000000000000001741 135.0
TLS2_k127_352836_8 ORF located using Blastx - - - 0.000000000000000000000001245 103.0
TLS2_k127_352836_9 - - - - 0.0000000007057 66.0
TLS2_k127_3539450_0 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 465.0
TLS2_k127_3539450_1 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 412.0
TLS2_k127_3539450_10 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.0000003572 56.0
TLS2_k127_3539450_2 Chemotaxis K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000006864 151.0
TLS2_k127_3539450_3 transmembrane transport - - - 0.00000000000000000000000000000000000003867 151.0
TLS2_k127_3539450_4 Transposase domain (DUF772) K07487 - - 0.000000000000000000003155 96.0
TLS2_k127_3539450_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000002495 96.0
TLS2_k127_3539450_6 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000001751 87.0
TLS2_k127_3539450_7 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000002869 81.0
TLS2_k127_3539450_8 Transposase or inactivated derivative - - - 0.00000000001025 65.0
TLS2_k127_3539450_9 Transposase DDE domain - - - 0.0000002485 59.0
TLS2_k127_3544943_0 TonB-dependent Receptor Plug Domain - - - 0.0 1446.0
TLS2_k127_3544943_1 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004182 248.0
TLS2_k127_3556380_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1002.0
TLS2_k127_3556380_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 368.0
TLS2_k127_3556380_2 Subtilase family K13276,K17734 - - 0.000000000000000000000003021 119.0
TLS2_k127_3585784_0 Cytochrome c - - - 0.0 1086.0
TLS2_k127_3585784_1 Protein of unknown function (DUF1501) - - - 2.862e-213 673.0
TLS2_k127_3605634_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 441.0
TLS2_k127_3605634_1 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 379.0
TLS2_k127_3605634_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 327.0
TLS2_k127_3605634_3 coenzyme F420 hydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 300.0
TLS2_k127_3605634_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000555 132.0
TLS2_k127_3606925_0 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 377.0
TLS2_k127_3606925_1 COGs COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000004864 232.0
TLS2_k127_3611011_0 long-chain fatty acid transporting porin activity - - - 4.039e-224 702.0
TLS2_k127_3611011_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000034 177.0
TLS2_k127_3622281_0 Protein of unknown function (DUF1501) - - - 1.923e-233 733.0
TLS2_k127_3622281_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 7.945e-213 673.0
TLS2_k127_3622281_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.000000000000000000000000000000000000000000000000000119 191.0
TLS2_k127_3622281_11 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000463 177.0
TLS2_k127_3622281_12 cell redox homeostasis - - - 0.0000000000000000000000000000000000001799 147.0
TLS2_k127_3622281_13 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.00000000000000000000000000000000532 130.0
TLS2_k127_3622281_15 Protein of unknown function (DUF3303) - - - 0.00000000000000003702 84.0
TLS2_k127_3622281_17 PFAM alpha beta hydrolase fold - - - 0.00000001682 57.0
TLS2_k127_3622281_2 single-stranded-DNA-specific exonuclease RecJ K07462 - - 5.175e-204 651.0
TLS2_k127_3622281_3 Pyrrolo-quinoline quinone K00117 - 1.1.5.2 3.756e-202 647.0
TLS2_k127_3622281_4 Aldehyde dehydrogenase family K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 1.676e-200 644.0
TLS2_k127_3622281_5 aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 546.0
TLS2_k127_3622281_6 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 421.0
TLS2_k127_3622281_7 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 288.0
TLS2_k127_3622281_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001598 281.0
TLS2_k127_3622281_9 Protein of unknown function (DUF1553) - - - 0.00000000000000000000000000000000000000000000000000000000000000007615 225.0
TLS2_k127_362771_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 539.0
TLS2_k127_362771_1 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 516.0
TLS2_k127_362771_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 380.0
TLS2_k127_362771_3 - - - - 0.0000000000000000000000006734 107.0
TLS2_k127_362771_4 addiction module antidote protein, CC2985 family K07746 - - 0.00000000001561 69.0
TLS2_k127_3629349_0 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 430.0
TLS2_k127_3629349_1 flagellar basal-body rod protein FlgC K02388 - - 0.000000000000000000000000000000000000000000000000001557 186.0
TLS2_k127_3629349_2 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000005448 126.0
TLS2_k127_3629349_3 ORF6N domain - - - 0.0000000000000000000006028 96.0
TLS2_k127_3629349_4 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000002593 79.0
TLS2_k127_3629349_5 PFAM PIN domain - - - 0.0000000000001643 72.0
TLS2_k127_3635816_0 Carboxypeptidase regulatory-like domain - - - 0.0 1025.0
TLS2_k127_3635816_1 SMART Elongator protein 3 MiaB NifB - - - 2.944e-225 711.0
TLS2_k127_3635816_10 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000001157 211.0
TLS2_k127_3635816_11 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000001395 174.0
TLS2_k127_3635816_12 - - - - 0.0000000000000000000000000000000000000000000004991 177.0
TLS2_k127_3635816_13 PFAM O-antigen polymerase - - - 0.000000000000000000000000000000000000000003106 170.0
TLS2_k127_3635816_14 Transcription termination factor nusG - - - 0.000000000000000000000000000000000000009132 154.0
TLS2_k127_3635816_15 Cytochrome c - - - 0.00000000000000000000002146 106.0
TLS2_k127_3635816_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 496.0
TLS2_k127_3635816_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 437.0
TLS2_k127_3635816_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 389.0
TLS2_k127_3635816_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 367.0
TLS2_k127_3635816_6 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 327.0
TLS2_k127_3635816_7 outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006671 247.0
TLS2_k127_3635816_8 PFAM PKD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001828 254.0
TLS2_k127_3635816_9 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000019 243.0
TLS2_k127_3657541_0 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 5.732e-270 855.0
TLS2_k127_3657541_1 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 571.0
TLS2_k127_3657541_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003627 240.0
TLS2_k127_3657541_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000001194 139.0
TLS2_k127_3657541_4 heme-binding domain, Pirellula Verrucomicrobium type - - - 0.0000008887 57.0
TLS2_k127_366870_0 Parallel beta-helix repeats - - - 4.124e-271 848.0
TLS2_k127_366870_1 Carboxypeptidase regulatory-like domain - - - 9.646e-266 854.0
TLS2_k127_366870_10 Phosphate acyltransferases K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 420.0
TLS2_k127_366870_11 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 385.0
TLS2_k127_366870_12 GTP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 386.0
TLS2_k127_366870_13 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 377.0
TLS2_k127_366870_14 mandelate racemase muconate lactonizing K18334 - 4.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 355.0
TLS2_k127_366870_15 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 346.0
TLS2_k127_366870_16 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 337.0
TLS2_k127_366870_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 343.0
TLS2_k127_366870_18 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000007757 248.0
TLS2_k127_366870_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003938 249.0
TLS2_k127_366870_2 4Fe-4S dicluster domain - - - 1.995e-264 827.0
TLS2_k127_366870_20 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000001619 225.0
TLS2_k127_366870_21 cell adhesion involved in biofilm formation K01186 - 3.2.1.18 0.000000000000000000000000000000000000000000000008424 198.0
TLS2_k127_366870_22 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000007727 123.0
TLS2_k127_366870_23 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000005603 109.0
TLS2_k127_366870_24 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000245 91.0
TLS2_k127_366870_25 Cell wall hydrolyses involved in spore germination - - - 0.000000000000000001 93.0
TLS2_k127_366870_26 Conserved repeat domain - - - 0.000000000000003906 91.0
TLS2_k127_366870_27 GTP binding - - - 0.0002182 52.0
TLS2_k127_366870_3 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 8.734e-226 738.0
TLS2_k127_366870_4 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 607.0
TLS2_k127_366870_5 AMP-binding enzyme C-terminal domain K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 569.0
TLS2_k127_366870_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 517.0
TLS2_k127_366870_7 PFAM NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 490.0
TLS2_k127_366870_8 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 491.0
TLS2_k127_366870_9 Fungalysin metallopeptidase (M36) K01417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 460.0
TLS2_k127_3743394_0 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 445.0
TLS2_k127_3743394_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 445.0
TLS2_k127_3743394_2 Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 394.0
TLS2_k127_3743394_3 Protein of unknown function (DUF1549) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 338.0
TLS2_k127_3743394_4 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002766 280.0
TLS2_k127_3743394_5 ABC transporter substrate-binding protein K02051 - - 0.00000000006104 66.0
TLS2_k127_3743394_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000004357 60.0
TLS2_k127_3743394_7 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00003146 52.0
TLS2_k127_3743427_0 COG0534 Na -driven multidrug efflux pump K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 451.0
TLS2_k127_3743427_1 protocatechuate 3,4-dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 371.0
TLS2_k127_3743427_2 intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000003833 172.0
TLS2_k127_3744195_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 503.0
TLS2_k127_3744195_1 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 421.0
TLS2_k127_3744195_10 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000285 48.0
TLS2_k127_3744195_2 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 382.0
TLS2_k127_3744195_3 Belongs to the LDH2 MDH2 oxidoreductase family K08092 - 1.1.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 380.0
TLS2_k127_3744195_4 Leishmanolysin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 325.0
TLS2_k127_3744195_5 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 314.0
TLS2_k127_3744195_6 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 283.0
TLS2_k127_3744195_7 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000002733 157.0
TLS2_k127_3744195_8 - - - - 0.0000001825 58.0
TLS2_k127_3744195_9 Membrane-flanked domain. Source PGD - - - 0.0000003603 59.0
TLS2_k127_3751143_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1411.0
TLS2_k127_3751143_1 - - - - 0.0 1154.0
TLS2_k127_3751143_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 481.0
TLS2_k127_3751143_3 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 422.0
TLS2_k127_3751143_4 PFAM Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 402.0
TLS2_k127_3751143_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 379.0
TLS2_k127_3751143_6 serine-type peptidase activity K03641 - - 0.000000000000000000000000000000000000000000000000000001245 216.0
TLS2_k127_3751143_7 HDOD domain - - - 0.000000000000000000000005222 113.0
TLS2_k127_3753889_0 Reduction of activated sulfate into sulfite K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 314.0
TLS2_k127_3753889_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000004883 225.0
TLS2_k127_3753889_2 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000007235 203.0
TLS2_k127_3753889_3 Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 K02303 - 2.1.1.107 0.00000000000000002505 86.0
TLS2_k127_3762503_0 COG0474 Cation transport ATPase K01531 - 3.6.3.2 2.129e-281 887.0
TLS2_k127_3762503_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.33e-244 764.0
TLS2_k127_3762503_2 mandelate racemase muconate lactonizing K01684,K01781,K08323 - 4.2.1.6,4.2.1.8,5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 401.0
TLS2_k127_3762503_3 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000006979 199.0
TLS2_k127_3762775_0 Carboxypeptidase regulatory-like domain - - - 0.0 1171.0
TLS2_k127_3762775_1 alpha beta - - - 5.004e-201 644.0
TLS2_k127_3762775_10 SMART regulatory protein, ArsR - - - 0.000000000000000000000000000000002381 130.0
TLS2_k127_3762775_12 Mu transposase, C-terminal K07497 - - 0.000000009225 57.0
TLS2_k127_3762775_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 580.0
TLS2_k127_3762775_3 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 546.0
TLS2_k127_3762775_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 301.0
TLS2_k127_3762775_5 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009603 257.0
TLS2_k127_3762775_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001076 234.0
TLS2_k127_3762775_7 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000008351 215.0
TLS2_k127_3762775_8 Belongs to the ompA family - - - 0.0000000000000000000000000000000000008272 149.0
TLS2_k127_3762775_9 Methyltransferase domain - - - 0.00000000000000000000000000000000000522 154.0
TLS2_k127_3769797_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 443.0
TLS2_k127_3769797_1 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000005144 176.0
TLS2_k127_3769797_2 Amidohydrolase family - - - 0.00000000000000000000000004682 108.0
TLS2_k127_3778446_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000005769 179.0
TLS2_k127_3778446_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000006339 164.0
TLS2_k127_3782944_0 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 9.998e-199 631.0
TLS2_k127_3782944_1 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000003908 231.0
TLS2_k127_3782944_2 Psort location Cytoplasmic, score - - - 0.000000000000000000003297 96.0
TLS2_k127_3782944_3 - - - - 0.000246 53.0
TLS2_k127_379744_0 Animal haem peroxidase - - - 2.549e-263 823.0
TLS2_k127_379744_1 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 356.0
TLS2_k127_379744_2 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 363.0
TLS2_k127_379744_3 PFAM FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 361.0
TLS2_k127_379744_4 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 336.0
TLS2_k127_379744_5 multi-organism process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009178 254.0
TLS2_k127_379744_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000002692 160.0
TLS2_k127_379744_7 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000001759 126.0
TLS2_k127_379744_8 Protein of unknown function (DUF2892) - - - 0.00000000000000000000001388 105.0
TLS2_k127_379744_9 Domain of unknown function (DUF4440) - - - 0.000000000000000749 84.0
TLS2_k127_3819396_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.862e-275 865.0
TLS2_k127_3819396_1 Amidase K01426 - 3.5.1.4 1.057e-222 704.0
TLS2_k127_3819396_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 595.0
TLS2_k127_3819396_3 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 461.0
TLS2_k127_3819396_4 Hypothetical methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009974 371.0
TLS2_k127_3819396_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000478 284.0
TLS2_k127_3819396_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000007434 150.0
TLS2_k127_3819396_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.000000000009469 71.0
TLS2_k127_3819396_8 Belongs to the MraZ family K03925 - - 0.000000009597 63.0
TLS2_k127_3819559_0 Cytochrome c, class I - - - 8.869e-202 656.0
TLS2_k127_3819559_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 576.0
TLS2_k127_3819559_2 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 561.0
TLS2_k127_3819559_3 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 336.0
TLS2_k127_3819559_4 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 329.0
TLS2_k127_3819559_5 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008456 304.0
TLS2_k127_3819559_6 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000001419 233.0
TLS2_k127_3819559_7 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000001158 192.0
TLS2_k127_3819559_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000006952 158.0
TLS2_k127_3819559_9 membrane organization K21449 - - 0.0000439 46.0
TLS2_k127_3822637_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 616.0
TLS2_k127_3822637_1 Dehydratase family K13875 - 4.2.1.25 0.00000000000000000000000000000000000000000000000000000000261 201.0
TLS2_k127_3829048_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 480.0
TLS2_k127_3829048_1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 424.0
TLS2_k127_3829048_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 404.0
TLS2_k127_3829048_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 367.0
TLS2_k127_3829048_4 ABC transporter K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 291.0
TLS2_k127_3829048_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 288.0
TLS2_k127_3829048_6 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002375 268.0
TLS2_k127_3829048_7 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000001403 194.0
TLS2_k127_3829048_8 Yhs domain-containing protein - - - 0.000000000000000000000000000000000000000000004544 168.0
TLS2_k127_3829048_9 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000005381 132.0
TLS2_k127_3832399_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1076.0
TLS2_k127_3832399_1 GTP-binding protein TypA K06207 - - 3.016e-311 966.0
TLS2_k127_3832399_10 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 533.0
TLS2_k127_3832399_11 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 534.0
TLS2_k127_3832399_12 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 504.0
TLS2_k127_3832399_13 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 472.0
TLS2_k127_3832399_14 TIGRFAM hopanoid-associated sugar epimerase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 449.0
TLS2_k127_3832399_15 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 428.0
TLS2_k127_3832399_16 PFAM Squalene phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 411.0
TLS2_k127_3832399_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 380.0
TLS2_k127_3832399_18 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 334.0
TLS2_k127_3832399_19 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001267 273.0
TLS2_k127_3832399_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 8.356e-282 879.0
TLS2_k127_3832399_20 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008793 263.0
TLS2_k127_3832399_21 Uncharacterized protein conserved in bacteria (DUF2239) K09965 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008789 243.0
TLS2_k127_3832399_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002561 246.0
TLS2_k127_3832399_23 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001523 233.0
TLS2_k127_3832399_24 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000001299 218.0
TLS2_k127_3832399_25 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000003887 213.0
TLS2_k127_3832399_26 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000007544 190.0
TLS2_k127_3832399_27 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000000000000000000000000000000001313 184.0
TLS2_k127_3832399_28 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000003544 179.0
TLS2_k127_3832399_29 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 0.00000000000000000000000000000000000000000000006376 193.0
TLS2_k127_3832399_3 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 1.365e-261 821.0
TLS2_k127_3832399_30 - - - - 0.0000000000000000000000000000000000000004846 161.0
TLS2_k127_3832399_31 Phosphorylase superfamily K01243 - 3.2.2.9 0.000000000000000000000000000000000000000888 156.0
TLS2_k127_3832399_32 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000007982 151.0
TLS2_k127_3832399_33 sequence-specific DNA binding - GO:0001666,GO:0006355,GO:0006950,GO:0008150,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010565,GO:0010605,GO:0010629,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036293,GO:0040008,GO:0045892,GO:0045926,GO:0045927,GO:0045934,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0070482,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000003254 136.0
TLS2_k127_3832399_34 - - - - 0.00000000000000000000000000002074 130.0
TLS2_k127_3832399_4 cytochrome C peroxidase - - - 4.178e-232 724.0
TLS2_k127_3832399_5 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.026e-231 724.0
TLS2_k127_3832399_6 Anion-transporting ATPase K01551 - 3.6.3.16 6.178e-201 635.0
TLS2_k127_3832399_7 COG3119 Arylsulfatase A and related enzymes - - - 2.927e-196 627.0
TLS2_k127_3832399_8 PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 584.0
TLS2_k127_3832399_9 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 582.0
TLS2_k127_383379_0 Cytochrome c, class I - - - 9.268e-268 844.0
TLS2_k127_383379_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 386.0
TLS2_k127_383379_2 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 295.0
TLS2_k127_383379_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000004434 207.0
TLS2_k127_383379_4 Putative zinc-finger - - - 0.00000001613 60.0
TLS2_k127_3835995_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 490.0
TLS2_k127_3835995_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009377 262.0
TLS2_k127_3846725_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000002728 211.0
TLS2_k127_3846725_1 Helix-turn-helix domain - - - 0.00000000000000000000000003978 113.0
TLS2_k127_3846725_2 - - - - 0.000000000000000000003398 97.0
TLS2_k127_3846725_3 COG1977 Molybdopterin converting factor, small subunit K03636 - - 0.0007844 42.0
TLS2_k127_3868732_0 serine-type peptidase activity - - - 3.58e-255 806.0
TLS2_k127_3868732_1 Involved in the tonB-independent uptake of proteins K01730 - 4.2.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 482.0
TLS2_k127_3868732_2 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001177 246.0
TLS2_k127_3868732_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001527 252.0
TLS2_k127_3868732_4 - - - - 0.00000000000000000000000000000000000000000000000000000000403 209.0
TLS2_k127_3868732_5 Protein of unknown function (DUF433) - - - 0.000000000000000000000000004087 111.0
TLS2_k127_3868732_7 - - - - 0.0000000000000001536 87.0
TLS2_k127_3868732_8 - - - - 0.0000344 48.0
TLS2_k127_3870948_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1182.0
TLS2_k127_3870948_1 efflux transmembrane transporter activity - - - 0.0 1041.0
TLS2_k127_3870948_10 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000636 66.0
TLS2_k127_3870948_11 - - - - 0.000000548 58.0
TLS2_k127_3870948_12 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.00073 44.0
TLS2_k127_3870948_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 3.276e-229 736.0
TLS2_k127_3870948_3 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 1.201e-205 653.0
TLS2_k127_3870948_4 Monoamine oxidase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 575.0
TLS2_k127_3870948_5 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000001064 227.0
TLS2_k127_3870948_6 - - - - 0.000000000000000000000000000000000000000000000000000000288 200.0
TLS2_k127_3870948_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000002053 192.0
TLS2_k127_3870948_8 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000000000000000000000000000243 166.0
TLS2_k127_3886301_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1412.0
TLS2_k127_3886301_1 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 2.081e-249 775.0
TLS2_k127_3886301_10 - - - - 0.0000000000000000000000000007666 115.0
TLS2_k127_3886301_12 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000002453 83.0
TLS2_k127_3886301_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 510.0
TLS2_k127_3886301_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 488.0
TLS2_k127_3886301_4 TonB dependent receptor K16089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 477.0
TLS2_k127_3886301_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 300.0
TLS2_k127_3886301_6 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000111 242.0
TLS2_k127_3886301_7 Alanine acetyltransferase K03817 - - 0.0000000000000000000000000000000000000000004639 169.0
TLS2_k127_3886301_8 nuclease activity K18828 - - 0.00000000000000000000000000000000002472 138.0
TLS2_k127_3886301_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000004188 125.0
TLS2_k127_3899145_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 341.0
TLS2_k127_3899145_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 322.0
TLS2_k127_3899145_2 Protein conserved in bacteria - - - 0.000000001507 63.0
TLS2_k127_3899145_3 - - - - 0.00001217 53.0
TLS2_k127_3899145_4 PepSY-associated TM region - - - 0.0001093 53.0
TLS2_k127_3904718_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 416.0
TLS2_k127_3904718_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004489 289.0
TLS2_k127_3913886_0 Sulfatase K01130 - 3.1.6.1 2.343e-203 648.0
TLS2_k127_3913886_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 497.0
TLS2_k127_3913886_2 PFAM Leukotriene A4 hydrolase, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 486.0
TLS2_k127_3913886_3 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 462.0
TLS2_k127_3913886_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 454.0
TLS2_k127_3913886_5 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001527 246.0
TLS2_k127_3913886_6 Tetratricopeptide repeat - - - 0.00000000000000000000001998 102.0
TLS2_k127_3921287_0 GMC oxidoreductase - - - 1.764e-306 947.0
TLS2_k127_3921287_1 HELICc2 K03722 - 3.6.4.12 2.063e-266 839.0
TLS2_k127_3921287_10 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000000000000000001393 193.0
TLS2_k127_3921287_12 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000000000000022 140.0
TLS2_k127_3921287_13 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000001033 138.0
TLS2_k127_3921287_14 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000003962 117.0
TLS2_k127_3921287_15 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000569 121.0
TLS2_k127_3921287_16 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000002673 113.0
TLS2_k127_3921287_17 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000004095 120.0
TLS2_k127_3921287_18 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000002782 83.0
TLS2_k127_3921287_19 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000001539 78.0
TLS2_k127_3921287_2 gluconolactonase activity K01053 - 3.1.1.17 3.288e-222 706.0
TLS2_k127_3921287_20 - - - - 0.0000001449 55.0
TLS2_k127_3921287_21 - - - - 0.00001468 56.0
TLS2_k127_3921287_3 Zinc carboxypeptidase - - - 8.845e-198 648.0
TLS2_k127_3921287_4 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 458.0
TLS2_k127_3921287_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 443.0
TLS2_k127_3921287_6 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 349.0
TLS2_k127_3921287_7 Inosine-uridine preferring nucleoside hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001423 275.0
TLS2_k127_3921287_9 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000001912 223.0
TLS2_k127_3939552_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 564.0
TLS2_k127_3939552_1 glucose sorbosone K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000009825 215.0
TLS2_k127_3939552_2 Beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000007906 187.0
TLS2_k127_3939552_3 pyrroloquinoline quinone binding K12349 - 3.5.1.23 0.000000000000000000000000000000001069 148.0
TLS2_k127_3939552_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000003923 66.0
TLS2_k127_3943885_0 TonB-dependent receptor - - - 0.0 1101.0
TLS2_k127_3943885_1 AcrB/AcrD/AcrF family K03296 - - 2.043e-302 960.0
TLS2_k127_3943885_10 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 342.0
TLS2_k127_3943885_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 304.0
TLS2_k127_3943885_12 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 294.0
TLS2_k127_3943885_13 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 286.0
TLS2_k127_3943885_14 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 291.0
TLS2_k127_3943885_15 protocatechuate 3,4-dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005488 280.0
TLS2_k127_3943885_16 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001621 253.0
TLS2_k127_3943885_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000007208 235.0
TLS2_k127_3943885_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005468 246.0
TLS2_k127_3943885_19 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000000000000000001227 228.0
TLS2_k127_3943885_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 6.76e-225 713.0
TLS2_k127_3943885_20 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000004194 234.0
TLS2_k127_3943885_21 Transcriptional regulator K22293 - - 0.00000000000000000000000000000000000000000000000000000004338 204.0
TLS2_k127_3943885_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000001072 194.0
TLS2_k127_3943885_24 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000002767 175.0
TLS2_k127_3943885_25 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000007505 125.0
TLS2_k127_3943885_26 transcriptional regulator (AraC family) - - - 0.0000000000000000000000002235 117.0
TLS2_k127_3943885_28 Putative zinc-binding metallo-peptidase - - - 0.00003401 48.0
TLS2_k127_3943885_29 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00007048 55.0
TLS2_k127_3943885_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 3.811e-198 624.0
TLS2_k127_3943885_4 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 623.0
TLS2_k127_3943885_5 Sulfate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 605.0
TLS2_k127_3943885_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 592.0
TLS2_k127_3943885_7 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 513.0
TLS2_k127_3943885_8 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 419.0
TLS2_k127_3943885_9 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 332.0
TLS2_k127_3944005_0 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 604.0
TLS2_k127_3944005_1 Belongs to the malate synthase family K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 499.0
TLS2_k127_3944005_10 cell wall anchor domain - - - 0.000000001782 70.0
TLS2_k127_3944005_2 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 364.0
TLS2_k127_3944005_3 protocatechuate 3,4-dioxygenase activity K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 319.0
TLS2_k127_3944005_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000003609 253.0
TLS2_k127_3944005_5 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000146 229.0
TLS2_k127_3944005_6 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000000000000004308 192.0
TLS2_k127_3944005_7 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000001041 144.0
TLS2_k127_3944005_8 - - - - 0.0000000000000000000000000000004057 130.0
TLS2_k127_3944005_9 cellulase activity K18197 - 4.2.2.23 0.0000000002167 75.0
TLS2_k127_3948010_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 363.0
TLS2_k127_3948010_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003118 265.0
TLS2_k127_3948010_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000005517 252.0
TLS2_k127_3948010_3 Methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000001896 231.0
TLS2_k127_3948010_4 Transposase DDE domain - - - 0.0000000000517 64.0
TLS2_k127_3966874_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 368.0
TLS2_k127_3966874_1 deoxyhypusine monooxygenase activity K03301 - - 0.000000000000001101 86.0
TLS2_k127_3969350_0 Short chain fatty acid transporter K02106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 342.0
TLS2_k127_3969350_1 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000005018 207.0
TLS2_k127_3969350_2 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 0.000000000000000000000000000001636 121.0
TLS2_k127_398387_0 transport - - - 5.515e-247 793.0
TLS2_k127_398387_1 long-chain fatty acid transporting porin activity - - - 7.533e-201 634.0
TLS2_k127_398387_10 - - - - 0.00000007595 62.0
TLS2_k127_398387_11 Carboxypeptidase regulatory-like domain - - - 0.0002838 52.0
TLS2_k127_398387_2 ABC transporter K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 471.0
TLS2_k127_398387_3 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 392.0
TLS2_k127_398387_4 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 351.0
TLS2_k127_398387_5 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 302.0
TLS2_k127_398387_6 Alkylated DNA repair protein K03919 - 1.14.11.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 298.0
TLS2_k127_398387_7 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000002838 163.0
TLS2_k127_398387_8 RNA-binding S4 domain protein K04762 - - 0.00000000000000000000000000000007779 139.0
TLS2_k127_398387_9 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000008624 121.0
TLS2_k127_3989191_0 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 397.0
TLS2_k127_3989191_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000003804 146.0
TLS2_k127_3989191_2 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000001041 95.0
TLS2_k127_4011326_0 Acetyl xylan esterase (AXE1) - - - 1.597e-297 928.0
TLS2_k127_4011326_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.478e-225 702.0
TLS2_k127_4011326_2 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 604.0
TLS2_k127_4011326_3 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 469.0
TLS2_k127_4011326_4 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 447.0
TLS2_k127_4011326_5 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K01856 - 5.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 359.0
TLS2_k127_4011326_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004016 270.0
TLS2_k127_4011326_7 Universal stress protein - - - 0.00000000000001365 87.0
TLS2_k127_4011326_8 Universal stress protein K06149 - - 0.00009446 54.0
TLS2_k127_4027479_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1270.0
TLS2_k127_4027479_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1018.0
TLS2_k127_4027479_10 peptidyl-tyrosine sulfation - - - 0.0001204 53.0
TLS2_k127_4027479_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 312.0
TLS2_k127_4027479_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 297.0
TLS2_k127_4027479_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003927 308.0
TLS2_k127_4027479_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000961 114.0
TLS2_k127_4027479_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000001913 110.0
TLS2_k127_4027479_7 cAMP biosynthetic process K03641,K08282,K12132 - 2.7.11.1 0.000000000000003738 91.0
TLS2_k127_4027479_8 Carboxypeptidase regulatory-like domain - - - 0.000000006149 61.0
TLS2_k127_4027479_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000007699 56.0
TLS2_k127_4045411_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 552.0
TLS2_k127_4045411_1 transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 361.0
TLS2_k127_4045411_2 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000116 238.0
TLS2_k127_4045411_3 transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000007397 207.0
TLS2_k127_4045411_4 ABC transporter permease K01992 - - 0.0000000000000000000000000000000000000000000000000000002709 205.0
TLS2_k127_4045411_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001871 128.0
TLS2_k127_4045411_6 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000005217 127.0
TLS2_k127_4045411_7 RES - - - 0.0000001635 57.0
TLS2_k127_4060188_0 PFAM Na Pi-cotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 518.0
TLS2_k127_4060188_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 334.0
TLS2_k127_4061888_0 D-alanine [D-alanyl carrier protein] ligase activity - - - 5.347e-286 904.0
TLS2_k127_4061888_1 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 573.0
TLS2_k127_4061888_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000003833 118.0
TLS2_k127_4079852_0 Carboxyl transferase domain - - - 1.912e-246 772.0
TLS2_k127_4079852_1 Acyclic terpene utilisation family protein AtuA - - - 1.084e-219 689.0
TLS2_k127_4079852_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 569.0
TLS2_k127_4079852_3 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 515.0
TLS2_k127_4079852_4 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 305.0
TLS2_k127_4079852_5 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000005287 233.0
TLS2_k127_4079852_6 - - - - 0.000000000000000000000000000000000002971 150.0
TLS2_k127_4079852_7 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.00000000000000000000000000000002767 145.0
TLS2_k127_4098913_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ - - - 4.79e-270 838.0
TLS2_k127_4098913_1 Sodium:solute symporter family - - - 1.095e-195 628.0
TLS2_k127_4098913_2 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 584.0
TLS2_k127_4098913_3 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 580.0
TLS2_k127_4098913_5 EamA-like transporter family - - - 0.000000000000000000000000000008112 123.0
TLS2_k127_410312_0 Haloacid dehalogenase domain protein hydrolase, type 3 - - - 2.603e-225 717.0
TLS2_k127_410312_1 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 2.431e-208 664.0
TLS2_k127_410312_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 296.0
TLS2_k127_410312_3 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 296.0
TLS2_k127_410312_4 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000008439 138.0
TLS2_k127_410312_5 PFAM SMP-30 Gluconolaconase K01053 - 3.1.1.17 0.00000000000000000000000001117 121.0
TLS2_k127_410312_6 Transposase domain (DUF772) K07487 - - 0.000000007235 59.0
TLS2_k127_4106538_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 613.0
TLS2_k127_4106538_1 Sh3 type 3 domain protein - - - 0.000000000000000000000000000000009924 133.0
TLS2_k127_4106538_2 PFAM WD40-like beta Propeller - - - 0.00000000000000000000000000006855 125.0
TLS2_k127_4112343_0 4Fe-4S dicluster domain K00184 - - 3.625e-318 990.0
TLS2_k127_4112343_1 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 549.0
TLS2_k127_4112343_10 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000008107 237.0
TLS2_k127_4112343_11 Bacterial transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000392 209.0
TLS2_k127_4112343_12 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000001556 167.0
TLS2_k127_4112343_2 dipeptidyl-peptidase activity K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 428.0
TLS2_k127_4112343_3 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 417.0
TLS2_k127_4112343_4 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 392.0
TLS2_k127_4112343_5 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 381.0
TLS2_k127_4112343_6 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 370.0
TLS2_k127_4112343_7 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 337.0
TLS2_k127_4112343_8 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 298.0
TLS2_k127_4112343_9 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 295.0
TLS2_k127_41302_0 Aconitase family (aconitate hydratase) - - - 0.0 1204.0
TLS2_k127_41302_1 PFAM TonB-dependent Receptor Plug - - - 0.0 1150.0
TLS2_k127_41302_10 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 496.0
TLS2_k127_41302_11 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 413.0
TLS2_k127_41302_12 Type III effector Hrp-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 417.0
TLS2_k127_41302_13 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 385.0
TLS2_k127_41302_14 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 370.0
TLS2_k127_41302_15 Phosphogluconate dehydrogenase (decarboxylating) C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 353.0
TLS2_k127_41302_16 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 355.0
TLS2_k127_41302_17 transferase activity, transferring glycosyl groups K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 357.0
TLS2_k127_41302_18 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 338.0
TLS2_k127_41302_19 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 356.0
TLS2_k127_41302_2 DNA topological change K03168 - 5.99.1.2 3.789e-316 986.0
TLS2_k127_41302_20 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 333.0
TLS2_k127_41302_21 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005732 253.0
TLS2_k127_41302_22 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000002632 243.0
TLS2_k127_41302_23 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008397 264.0
TLS2_k127_41302_24 PFAM cyclase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000003216 229.0
TLS2_k127_41302_25 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000005722 220.0
TLS2_k127_41302_26 - - - - 0.000000000000000000000000000000000000000000000000000000000008968 217.0
TLS2_k127_41302_27 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000307 203.0
TLS2_k127_41302_28 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000006649 157.0
TLS2_k127_41302_29 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000002927 151.0
TLS2_k127_41302_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.456e-254 790.0
TLS2_k127_41302_30 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000004263 159.0
TLS2_k127_41302_31 Belongs to the PdxA family K00097 - 1.1.1.262 0.0000000000000000000000000000000002674 134.0
TLS2_k127_41302_32 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000000000002061 130.0
TLS2_k127_41302_33 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000001593 128.0
TLS2_k127_41302_34 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000004499 130.0
TLS2_k127_41302_35 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000008747 123.0
TLS2_k127_41302_36 cAMP biosynthetic process - - - 0.000000000000000000005867 109.0
TLS2_k127_41302_37 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000003129 92.0
TLS2_k127_41302_38 AntiSigma factor - - - 0.00000000000000001486 92.0
TLS2_k127_41302_39 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000001257 88.0
TLS2_k127_41302_4 Carboxypeptidase regulatory-like domain - - - 2.95e-250 808.0
TLS2_k127_41302_40 Domain of unknown function (DUF4160) - - - 0.0000000000000615 75.0
TLS2_k127_41302_42 CHAT domain - - - 0.000000006982 64.0
TLS2_k127_41302_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 4.167e-214 673.0
TLS2_k127_41302_6 Protein of unknown function (DUF1552) - - - 6.879e-208 659.0
TLS2_k127_41302_7 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 609.0
TLS2_k127_41302_8 Ribulose bisphosphate carboxylase large chain, N-terminal domain K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 604.0
TLS2_k127_41302_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 597.0
TLS2_k127_4138570_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1335.0
TLS2_k127_4138570_1 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 420.0
TLS2_k127_4138570_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 398.0
TLS2_k127_4138570_3 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 400.0
TLS2_k127_4138570_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 307.0
TLS2_k127_4138570_5 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008912 268.0
TLS2_k127_4138570_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000115 226.0
TLS2_k127_4138570_7 deaminase activity K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000001496 206.0
TLS2_k127_4138570_8 ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000968 201.0
TLS2_k127_415704_0 COG3119 Arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 457.0
TLS2_k127_415704_1 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 346.0
TLS2_k127_4167953_0 self proteolysis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 317.0
TLS2_k127_4167953_1 - - - - 0.000000000000000000000001541 108.0
TLS2_k127_4167953_2 transposase IS116 IS110 IS902 family - - - 0.0000000000000000005672 93.0
TLS2_k127_4167953_3 Transposase K07486 - - 0.000008304 54.0
TLS2_k127_4167953_4 Transposase IS116/IS110/IS902 family - - - 0.00003922 47.0
TLS2_k127_4172896_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 430.0
TLS2_k127_4172896_1 amino acid K03294 - - 0.0000000001056 62.0
TLS2_k127_4172896_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.000003462 50.0
TLS2_k127_4186873_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.09e-229 720.0
TLS2_k127_4186873_1 Cytochrome c, class I - - - 5.419e-227 724.0
TLS2_k127_4186873_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 487.0
TLS2_k127_4186873_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006279 265.0
TLS2_k127_4187497_0 deoxyhypusine monooxygenase activity K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 638.0
TLS2_k127_4187497_1 cellulase activity - - - 0.000000000000001043 93.0
TLS2_k127_4187547_0 Protein of unknown function (DUF1553) - - - 6.171e-284 899.0
TLS2_k127_4187547_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 413.0
TLS2_k127_4187547_2 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 307.0
TLS2_k127_4187547_3 protein containing double-stranded beta helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002329 244.0
TLS2_k127_4194385_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 7.027e-232 728.0
TLS2_k127_4194385_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 401.0
TLS2_k127_4194385_2 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 321.0
TLS2_k127_4194385_3 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000000009154 162.0
TLS2_k127_4208067_0 Phage tail sheath C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 291.0
TLS2_k127_4208067_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000001679 243.0
TLS2_k127_4208067_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000002423 222.0
TLS2_k127_4208067_3 - - - - 0.000000000000000000008628 98.0
TLS2_k127_4212373_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 552.0
TLS2_k127_4212373_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 539.0
TLS2_k127_4212373_11 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000004705 73.0
TLS2_k127_4212373_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 485.0
TLS2_k127_4212373_3 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 428.0
TLS2_k127_4212373_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 422.0
TLS2_k127_4212373_5 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 334.0
TLS2_k127_4212373_6 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 327.0
TLS2_k127_4212373_7 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 313.0
TLS2_k127_4212373_8 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 305.0
TLS2_k127_4212373_9 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000001248 160.0
TLS2_k127_4223973_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 376.0
TLS2_k127_4223973_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000001719 141.0
TLS2_k127_423047_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 2.019e-207 664.0
TLS2_k127_423047_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 413.0
TLS2_k127_4246336_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 529.0
TLS2_k127_4246336_1 Bacterial-like globin K06886 - - 0.000000000000000000000000000000001116 134.0
TLS2_k127_4246336_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000007377 106.0
TLS2_k127_4246336_3 PKD domain containing protein - - - 0.0000001523 64.0
TLS2_k127_4261436_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 419.0
TLS2_k127_4261436_1 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 308.0
TLS2_k127_4261436_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 288.0
TLS2_k127_4261436_3 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000003884 212.0
TLS2_k127_4261436_4 agmatine deiminase activity K10536 - 3.5.3.12 0.000000000000000796 81.0
TLS2_k127_4277038_0 Protein of unknown function (DUF1343) - - - 2.509e-290 910.0
TLS2_k127_4277038_1 Cytochrome c, class I - - - 3.714e-246 786.0
TLS2_k127_4277038_10 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 379.0
TLS2_k127_4277038_11 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 388.0
TLS2_k127_4277038_12 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 338.0
TLS2_k127_4277038_13 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 325.0
TLS2_k127_4277038_14 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 304.0
TLS2_k127_4277038_15 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008528 277.0
TLS2_k127_4277038_16 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000006793 206.0
TLS2_k127_4277038_17 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000003223 139.0
TLS2_k127_4277038_19 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000002163 100.0
TLS2_k127_4277038_2 AAA ATPase K07478 - - 3.594e-201 636.0
TLS2_k127_4277038_20 CHASE4 domain - - - 0.0000000264 63.0
TLS2_k127_4277038_21 Xylose isomerase K09136 - - 0.00002914 55.0
TLS2_k127_4277038_3 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 611.0
TLS2_k127_4277038_4 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 576.0
TLS2_k127_4277038_5 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 563.0
TLS2_k127_4277038_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 535.0
TLS2_k127_4277038_7 Domain of unknown function (DUF1972) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 496.0
TLS2_k127_4277038_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 490.0
TLS2_k127_4277038_9 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 389.0
TLS2_k127_4288664_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1525.0
TLS2_k127_4288664_1 Heat shock 70 kDa protein K04043 - - 1.175e-317 983.0
TLS2_k127_4288664_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 411.0
TLS2_k127_4288664_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 408.0
TLS2_k127_4288664_12 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 306.0
TLS2_k127_4288664_13 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001238 278.0
TLS2_k127_4288664_14 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000001556 218.0
TLS2_k127_4288664_15 TIGRFAM molybdenum cofactor synthesis - - - 0.000000000000000000000000000000000000000000000000000000000003722 213.0
TLS2_k127_4288664_16 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000000000000000000000003319 176.0
TLS2_k127_4288664_17 acr, cog1993 K09137 - - 0.0000000000000000000000002053 117.0
TLS2_k127_4288664_18 PFAM response regulator receiver - - - 0.0000000000000000000000006002 109.0
TLS2_k127_4288664_19 - - - - 0.00000000000000000001713 95.0
TLS2_k127_4288664_2 Bacterial regulatory protein, Fis family K07714 - - 3.518e-197 623.0
TLS2_k127_4288664_20 Protein of unknown function (DUF3309) - - - 0.000000000000004313 78.0
TLS2_k127_4288664_21 Protein of unknown function (DUF433) - - - 0.00000000000009066 75.0
TLS2_k127_4288664_3 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 548.0
TLS2_k127_4288664_4 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 515.0
TLS2_k127_4288664_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 516.0
TLS2_k127_4288664_6 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 477.0
TLS2_k127_4288664_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 472.0
TLS2_k127_4288664_8 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 441.0
TLS2_k127_4288664_9 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 419.0
TLS2_k127_4291533_0 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 366.0
TLS2_k127_4291533_1 -O-antigen K02847,K13009 - - 0.0000000000000000000000000000000000000000000000000000000000000005281 239.0
TLS2_k127_4291533_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000008133 140.0
TLS2_k127_4291533_4 Universal stress protein family - - - 0.000001176 56.0
TLS2_k127_429908_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 638.0
TLS2_k127_429908_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 324.0
TLS2_k127_429908_2 GAF domain K01768,K02584,K07183,K22010 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 304.0
TLS2_k127_429908_3 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000009154 205.0
TLS2_k127_429908_4 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000000000000000596 143.0
TLS2_k127_429908_5 EamA-like transporter family - - - 0.0000000000000000000000000001747 127.0
TLS2_k127_429908_6 - - - - 0.0000001104 57.0
TLS2_k127_429908_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0046872,GO:0046914,GO:0046983,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.000002543 54.0
TLS2_k127_4324943_0 Belongs to the MIP aquaporin (TC 1.A.8) family K02440,K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 364.0
TLS2_k127_4324943_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 294.0
TLS2_k127_4324943_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000136 169.0
TLS2_k127_4327436_0 WD40-like Beta Propeller Repeat - - - 1.959e-230 753.0
TLS2_k127_4327436_1 protocatechuate 3,4-dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 589.0
TLS2_k127_4327436_2 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 394.0
TLS2_k127_4327436_3 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 359.0
TLS2_k127_4327436_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 325.0
TLS2_k127_4327436_5 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 308.0
TLS2_k127_4327436_6 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000002329 191.0
TLS2_k127_434197_0 PQQ-like domain K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 289.0
TLS2_k127_434197_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000003335 228.0
TLS2_k127_434197_2 universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000006746 204.0
TLS2_k127_434197_3 metal cluster binding - - - 0.000000000000000000000000000000000000000005144 163.0
TLS2_k127_434197_4 Tetratricopeptide repeat - - - 0.00000000009221 72.0
TLS2_k127_4354886_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 453.0
TLS2_k127_4354886_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 434.0
TLS2_k127_4354886_10 Short-chain dehydrogenase reductase Sdr - - - 0.0000000000000001472 91.0
TLS2_k127_4354886_2 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 408.0
TLS2_k127_4354886_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 396.0
TLS2_k127_4354886_4 COG4422 Bacteriophage protein gp37 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 385.0
TLS2_k127_4354886_5 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 347.0
TLS2_k127_4354886_6 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 330.0
TLS2_k127_4354886_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 317.0
TLS2_k127_4354886_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000005867 161.0
TLS2_k127_4354886_9 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000005173 164.0
TLS2_k127_4359144_0 HypF finger K04656 - - 2.074e-273 857.0
TLS2_k127_4359144_1 Hydrogenase formation hypA family K04654 - - 1.853e-198 625.0
TLS2_k127_4359144_2 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 548.0
TLS2_k127_4359144_3 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 501.0
TLS2_k127_4359144_4 HupF/HypC family K04653 - - 0.0000000000000000000000000004665 116.0
TLS2_k127_4359144_5 YceI-like domain - - - 0.0000000000000004314 86.0
TLS2_k127_4360874_0 Peptidase M16 - - - 0.0 1164.0
TLS2_k127_4360874_1 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 514.0
TLS2_k127_4360874_10 synthase K01719,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000006383 264.0
TLS2_k127_4360874_11 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002814 253.0
TLS2_k127_4360874_12 Pfam:Methyltransf_6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000112 248.0
TLS2_k127_4360874_13 FMN reductase (NADPH) activity - - - 0.0000000000000000000000000000000000000000000000000003549 190.0
TLS2_k127_4360874_15 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000405 168.0
TLS2_k127_4360874_16 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000007509 135.0
TLS2_k127_4360874_17 Belongs to the 'phage' integrase family - - - 0.0000000000000002306 82.0
TLS2_k127_4360874_18 - - - - 0.0000000000000004111 79.0
TLS2_k127_4360874_19 Phosphopantetheine attachment site - - - 0.00000000000001066 83.0
TLS2_k127_4360874_2 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 508.0
TLS2_k127_4360874_20 dienelactone hydrolase K01061 - 3.1.1.45 0.00000001047 64.0
TLS2_k127_4360874_21 Protein of unknown function (DUF1304) K08987 - - 0.000001255 55.0
TLS2_k127_4360874_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 457.0
TLS2_k127_4360874_4 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 408.0
TLS2_k127_4360874_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 369.0
TLS2_k127_4360874_6 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 290.0
TLS2_k127_4360874_7 PFAM Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001482 284.0
TLS2_k127_4360874_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001113 297.0
TLS2_k127_4360874_9 Belongs to the Pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000622 264.0
TLS2_k127_4366188_0 Subtilase family - - - 7.971e-280 896.0
TLS2_k127_4366188_1 Protein of unknown function, DUF255 K06888 - - 9.423e-275 864.0
TLS2_k127_4366188_10 Redoxin K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000002197 236.0
TLS2_k127_4366188_11 DoxX-like family - - - 0.00000000000000000000000000000000000000000000000005228 182.0
TLS2_k127_4366188_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000005058 152.0
TLS2_k127_4366188_13 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.0000000000000000000000000000002278 127.0
TLS2_k127_4366188_14 - - - - 0.000000000000000000000000000001285 130.0
TLS2_k127_4366188_15 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.000000000000000000000000000007774 123.0
TLS2_k127_4366188_16 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000976 127.0
TLS2_k127_4366188_17 Belongs to the ATPase B chain family K02109 - - 0.000000000000000000000001313 108.0
TLS2_k127_4366188_18 - - - - 0.00000000000000004241 83.0
TLS2_k127_4366188_19 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000581 85.0
TLS2_k127_4366188_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.72e-263 824.0
TLS2_k127_4366188_20 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000001363 66.0
TLS2_k127_4366188_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.114e-254 792.0
TLS2_k127_4366188_4 BNR repeat-like domain K05989 - 3.2.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 557.0
TLS2_k127_4366188_5 COG3119 Arylsulfatase A K01132 - 3.1.6.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 487.0
TLS2_k127_4366188_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 475.0
TLS2_k127_4366188_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 387.0
TLS2_k127_4366188_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 334.0
TLS2_k127_4366188_9 Glyoxalase-like domain K07032 - - 0.000000000000000000000000000000000000000000000000000000000000000000002216 237.0
TLS2_k127_437919_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 601.0
TLS2_k127_437919_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000002619 164.0
TLS2_k127_437919_2 efflux transmembrane transporter activity - - - 0.00000000000000000002293 96.0
TLS2_k127_4383293_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 5.049e-199 626.0
TLS2_k127_4383293_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 569.0
TLS2_k127_4383293_2 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001095 229.0
TLS2_k127_4383293_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000004747 199.0
TLS2_k127_4383293_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000006236 169.0
TLS2_k127_4383293_5 Transposase - - - 0.0003328 44.0
TLS2_k127_4429057_0 BNR repeat-like domain K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 414.0
TLS2_k127_4429057_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000189 257.0
TLS2_k127_4429057_2 HDOD domain - - - 0.0000000000000000000000000000000000004186 154.0
TLS2_k127_4440314_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.726e-289 896.0
TLS2_k127_4440314_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 456.0
TLS2_k127_4440314_10 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000000001324 128.0
TLS2_k127_4440314_11 - - - - 0.0000000000000000000000002917 109.0
TLS2_k127_4440314_12 addiction module antidote protein HigA K21498 - - 0.00000000000000000001508 93.0
TLS2_k127_4440314_13 PFAM peptidase M48 Ste24p - - - 0.00000000000003016 79.0
TLS2_k127_4440314_14 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000001311 79.0
TLS2_k127_4440314_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 450.0
TLS2_k127_4440314_3 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 367.0
TLS2_k127_4440314_4 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 370.0
TLS2_k127_4440314_5 transmembrane transporter activity K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 319.0
TLS2_k127_4440314_6 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 293.0
TLS2_k127_4440314_7 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006101 255.0
TLS2_k127_4440314_8 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000003776 236.0
TLS2_k127_4440314_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000003716 163.0
TLS2_k127_4441706_0 PFAM Amino acid permease K03294 - - 1.174e-198 632.0
TLS2_k127_4441706_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 531.0
TLS2_k127_4441706_2 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 417.0
TLS2_k127_4441706_3 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 359.0
TLS2_k127_4441706_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 305.0
TLS2_k127_4441706_5 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000001091 194.0
TLS2_k127_4441706_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.00000000001069 74.0
TLS2_k127_4447926_0 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 607.0
TLS2_k127_4447926_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 501.0
TLS2_k127_4447926_2 amino acid carrier protein K03310 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 463.0
TLS2_k127_4447926_3 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 418.0
TLS2_k127_4447926_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 407.0
TLS2_k127_4447926_5 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 377.0
TLS2_k127_4447926_7 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000003818 119.0
TLS2_k127_4460578_0 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 379.0
TLS2_k127_4460578_1 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 319.0
TLS2_k127_4460578_2 cell redox homeostasis K03671 - - 0.00000000000000000000000000000000000000004348 158.0
TLS2_k127_4460578_3 efflux transmembrane transporter activity - - - 0.00000000000000000004791 100.0
TLS2_k127_4460578_4 - - - - 0.000004375 56.0
TLS2_k127_4499903_0 - - - - 2.072e-270 846.0
TLS2_k127_4499903_1 cellulose binding - - - 1.108e-218 691.0
TLS2_k127_4499903_10 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000005961 235.0
TLS2_k127_4499903_11 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008985 239.0
TLS2_k127_4499903_12 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000005846 201.0
TLS2_k127_4499903_13 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000001153 175.0
TLS2_k127_4499903_14 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000000000000000000001396 159.0
TLS2_k127_4499903_15 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000002818 144.0
TLS2_k127_4499903_16 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000000003239 148.0
TLS2_k127_4499903_17 ankyrin repeats - - - 0.000000000000000259 89.0
TLS2_k127_4499903_18 DNA-templated transcription, initiation K03088 - - 0.000000000000000722 86.0
TLS2_k127_4499903_19 - - - - 0.00000000000678 77.0
TLS2_k127_4499903_2 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 402.0
TLS2_k127_4499903_20 Putative zinc-finger - - - 0.00000000003271 75.0
TLS2_k127_4499903_21 ABC transporter substrate binding protein K01989 - - 0.000000001076 69.0
TLS2_k127_4499903_3 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 288.0
TLS2_k127_4499903_4 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000108 297.0
TLS2_k127_4499903_5 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003334 271.0
TLS2_k127_4499903_6 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001459 265.0
TLS2_k127_4499903_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000153 256.0
TLS2_k127_4499903_8 Protein of unknown function (DUF507) K09804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003817 245.0
TLS2_k127_4499903_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003535 257.0
TLS2_k127_4511561_0 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 477.0
TLS2_k127_4511561_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 432.0
TLS2_k127_4511561_2 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008375 331.0
TLS2_k127_4511561_3 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 305.0
TLS2_k127_4511561_4 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000005296 190.0
TLS2_k127_4511561_5 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000003321 132.0
TLS2_k127_4511561_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000001817 108.0
TLS2_k127_4511561_7 Xylose isomerase-like TIM barrel - - - 0.000000000002629 80.0
TLS2_k127_4511561_8 - - - - 0.00000004684 57.0
TLS2_k127_4519971_0 Carboxypeptidase regulatory-like domain - - - 0.0 1273.0
TLS2_k127_4519971_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 375.0
TLS2_k127_4519971_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003836 268.0
TLS2_k127_4519971_3 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000001843 177.0
TLS2_k127_4519971_4 Amidohydrolase - - - 0.00000000000002281 79.0
TLS2_k127_4519971_5 Protein kinase domain K12132 - 2.7.11.1 0.00000006339 61.0
TLS2_k127_4523433_0 Protein of unknown function (DUF1549) - - - 3.695e-240 751.0
TLS2_k127_4531744_0 E-Z type HEAT repeats - - - 1.92e-247 804.0
TLS2_k127_4531744_1 PFAM carbohydrate kinase K00853 - 2.7.1.16 3.839e-233 732.0
TLS2_k127_4531744_2 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 603.0
TLS2_k127_4531744_3 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 361.0
TLS2_k127_4531744_4 acyl-coa hydrolase K01073 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 0.000000000000000000000000000000000000000000000000000001387 210.0
TLS2_k127_4531744_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000007962 122.0
TLS2_k127_4531744_6 Hfq protein - - - 0.00000000000000000000000000002033 121.0
TLS2_k127_4547478_0 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 525.0
TLS2_k127_4547478_1 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 541.0
TLS2_k127_4547478_10 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000006946 110.0
TLS2_k127_4547478_11 High confidence in function and specificity - - - 0.00000000000000000000002807 103.0
TLS2_k127_4547478_12 translation initiation factor activity - - - 0.00000000000000000000002855 116.0
TLS2_k127_4547478_13 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14392 - - 0.00000000000000000000008488 103.0
TLS2_k127_4547478_15 High confidence in function and specificity - - - 0.000000000000000139 83.0
TLS2_k127_4547478_16 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000001474 84.0
TLS2_k127_4547478_17 - - - - 0.000000000000004682 79.0
TLS2_k127_4547478_18 leukotriene A-4 hydrolase - - - 0.0000000001437 66.0
TLS2_k127_4547478_19 PFAM PemK-like protein K07171 - - 0.000000001809 63.0
TLS2_k127_4547478_2 Protein of unknown function (DUF1549) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 509.0
TLS2_k127_4547478_20 PFAM Integrase catalytic - - - 0.000000002863 61.0
TLS2_k127_4547478_21 transposase activity - - - 0.00000002865 66.0
TLS2_k127_4547478_22 High confidence in function and specificity - - - 0.0000001167 60.0
TLS2_k127_4547478_23 Peptidase family M50 - - - 0.0000008862 55.0
TLS2_k127_4547478_24 Bacterial regulatory protein, Fis family K02584 - - 0.000001405 54.0
TLS2_k127_4547478_25 - - - - 0.000001973 53.0
TLS2_k127_4547478_26 - - - - 0.00008419 48.0
TLS2_k127_4547478_3 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 487.0
TLS2_k127_4547478_4 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 464.0
TLS2_k127_4547478_5 eRF1 domain 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 386.0
TLS2_k127_4547478_6 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 377.0
TLS2_k127_4547478_7 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 360.0
TLS2_k127_4547478_8 SMP-30 Gluconolaconase K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002444 289.0
TLS2_k127_4547478_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001339 170.0
TLS2_k127_4556710_0 Fibronectin type III domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000103 232.0
TLS2_k127_4556710_1 Small Multidrug Resistance protein - - - 0.000000000000000000000000000000000006389 146.0
TLS2_k127_4556710_2 Multidrug Resistance protein - - - 0.000000000000000000003302 98.0
TLS2_k127_4563558_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000004919 235.0
TLS2_k127_4563558_1 - K06862 - - 0.0000000000000000000000000000000004662 131.0
TLS2_k127_4577559_0 BNR repeat-like domain K05989 - 3.2.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 482.0
TLS2_k127_4577559_1 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 366.0
TLS2_k127_4577559_2 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000001486 179.0
TLS2_k127_4592679_0 PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain K00012 - 1.1.1.22 6.745e-196 620.0
TLS2_k127_4592679_1 Metalloenzyme superfamily K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 578.0
TLS2_k127_4592679_10 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 377.0
TLS2_k127_4592679_11 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 366.0
TLS2_k127_4592679_12 Nucleotidyl transferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 364.0
TLS2_k127_4592679_13 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 368.0
TLS2_k127_4592679_14 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 361.0
TLS2_k127_4592679_15 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 353.0
TLS2_k127_4592679_16 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 308.0
TLS2_k127_4592679_17 Putative collagen-binding domain of a collagenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 313.0
TLS2_k127_4592679_18 Putative collagen-binding domain of a collagenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 321.0
TLS2_k127_4592679_19 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008623 282.0
TLS2_k127_4592679_2 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008053 565.0
TLS2_k127_4592679_20 PFAM GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002119 263.0
TLS2_k127_4592679_21 PFAM Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005666 256.0
TLS2_k127_4592679_22 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004215 256.0
TLS2_k127_4592679_23 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000001038 246.0
TLS2_k127_4592679_24 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007296 250.0
TLS2_k127_4592679_25 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001643 241.0
TLS2_k127_4592679_26 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000006656 241.0
TLS2_k127_4592679_27 methyltransferase activity K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044464 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000009514 214.0
TLS2_k127_4592679_28 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000002996 209.0
TLS2_k127_4592679_29 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000001444 204.0
TLS2_k127_4592679_3 Domain of unknown function (DUF4910) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 557.0
TLS2_k127_4592679_30 PFAM ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000004621 185.0
TLS2_k127_4592679_31 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000008853 160.0
TLS2_k127_4592679_32 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000007288 150.0
TLS2_k127_4592679_33 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000316 141.0
TLS2_k127_4592679_34 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000002389 137.0
TLS2_k127_4592679_35 aminopeptidase activity K19701 - 3.4.11.10,3.4.11.6 0.00000000000000000000000000000061 141.0
TLS2_k127_4592679_36 polysaccharide export protein K01991 - - 0.0000000000000000000000000000008595 134.0
TLS2_k127_4592679_37 Fibronectin type 3 domain - - - 0.0000000000000000000000000005304 134.0
TLS2_k127_4592679_38 PFAM O-antigen polymerase - - - 0.00000000000000000000000006387 112.0
TLS2_k127_4592679_39 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000001184 108.0
TLS2_k127_4592679_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 548.0
TLS2_k127_4592679_40 transferase activity, transferring glycosyl groups - - - 0.0000000000000000002722 100.0
TLS2_k127_4592679_41 pilus organization - - - 0.000000000000000005489 101.0
TLS2_k127_4592679_42 metallopeptidase activity - - - 0.000000000000003985 92.0
TLS2_k127_4592679_43 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.00000000000001195 90.0
TLS2_k127_4592679_44 Glycosyltransferase like family 2 - - - 0.0000000000001751 81.0
TLS2_k127_4592679_45 Glycosyl transferases group 1 K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.0000000000002093 83.0
TLS2_k127_4592679_5 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 498.0
TLS2_k127_4592679_6 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 473.0
TLS2_k127_4592679_7 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 450.0
TLS2_k127_4592679_8 PFAM GHMP kinase K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 436.0
TLS2_k127_4592679_9 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 427.0
TLS2_k127_4594995_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000009522 158.0
TLS2_k127_4594995_1 DinB family - - - 0.000000000000000000463 94.0
TLS2_k127_4594995_2 transcriptional regulator K11914 - - 0.0000000000000000876 83.0
TLS2_k127_4594995_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000001624 67.0
TLS2_k127_46073_0 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 415.0
TLS2_k127_4609437_0 Carboxypeptidase regulatory-like domain - - - 1.18e-321 1022.0
TLS2_k127_4609437_1 Planctomycete cytochrome C - - - 1.599e-229 740.0
TLS2_k127_4609437_2 Transcriptional regulator - - - 0.000000000000000000000001372 115.0
TLS2_k127_4609437_3 EamA-like transporter family - - - 0.0000005819 55.0
TLS2_k127_461670_0 Ferrous iron transport protein B K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 483.0
TLS2_k127_461670_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 381.0
TLS2_k127_461670_2 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000002627 181.0
TLS2_k127_461670_3 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000000000002198 104.0
TLS2_k127_461670_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.00000000001151 68.0
TLS2_k127_4618063_0 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 578.0
TLS2_k127_4618063_1 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 594.0
TLS2_k127_4618063_2 Oxidoreductase family, NAD-binding Rossmann fold K19181 - 1.1.1.292 0.00000000000000000000000000000000000000000001906 165.0
TLS2_k127_4618063_3 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.0000000000000000004371 96.0
TLS2_k127_4618063_4 ParE toxin of type II toxin-antitoxin system, parDE K07746,K19092 - - 0.00003744 48.0
TLS2_k127_4642710_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1472.0
TLS2_k127_4642710_1 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 8.632e-197 634.0
TLS2_k127_4642710_10 response regulator K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003813 280.0
TLS2_k127_4642710_11 YCII-related domain - - - 0.0000000000000000000000000000000000000000000003058 168.0
TLS2_k127_4642710_12 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000008054 167.0
TLS2_k127_4642710_13 DinB superfamily - - - 0.000000000000000000000000000000009803 136.0
TLS2_k127_4642710_14 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000004716 123.0
TLS2_k127_4642710_15 DoxX-like family - - - 0.0000000000000000000000000001187 121.0
TLS2_k127_4642710_17 Histidine kinase K07675 - 2.7.13.3 0.00000000000005931 80.0
TLS2_k127_4642710_18 PFAM Tetratricopeptide repeat - - - 0.00000002003 67.0
TLS2_k127_4642710_2 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 610.0
TLS2_k127_4642710_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 571.0
TLS2_k127_4642710_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 505.0
TLS2_k127_4642710_5 PFAM delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 497.0
TLS2_k127_4642710_6 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 420.0
TLS2_k127_4642710_7 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 379.0
TLS2_k127_4642710_8 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 350.0
TLS2_k127_4642710_9 Putative DNA-binding domain K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 317.0
TLS2_k127_4653701_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 2.15e-217 685.0
TLS2_k127_4653701_1 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 567.0
TLS2_k127_4653701_10 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000000001096 203.0
TLS2_k127_4653701_11 methyltransferase - - - 0.000000000000000000000000000000000000000001365 164.0
TLS2_k127_4653701_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.0000000000000000000000000000000000001725 144.0
TLS2_k127_4653701_13 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000000008652 64.0
TLS2_k127_4653701_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 486.0
TLS2_k127_4653701_3 TROVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 468.0
TLS2_k127_4653701_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 374.0
TLS2_k127_4653701_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 374.0
TLS2_k127_4653701_6 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 349.0
TLS2_k127_4653701_7 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 331.0
TLS2_k127_4653701_8 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 312.0
TLS2_k127_4653701_9 Glucose inhibited division protein A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001151 292.0
TLS2_k127_4660075_0 FAD linked oxidase domain protein K05797 - 1.17.99.1 2.416e-224 709.0
TLS2_k127_4660075_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 589.0
TLS2_k127_4660075_10 (FHA) domain - - - 0.000001172 61.0
TLS2_k127_4660075_11 Pectate lyase - - - 0.00002264 58.0
TLS2_k127_4660075_2 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 332.0
TLS2_k127_4660075_3 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 301.0
TLS2_k127_4660075_4 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000004626 209.0
TLS2_k127_4660075_5 hemolysin - - - 0.00000000000000000000000000000000000000000000000000006495 198.0
TLS2_k127_4660075_6 Transglycosylase K08307 - - 0.0000000000000000000000000000000005089 148.0
TLS2_k127_4660075_7 membrane - - - 0.000000000000000000000000000004383 136.0
TLS2_k127_4660075_8 metallopeptidase activity - - - 0.0000000000002985 81.0
TLS2_k127_4681460_0 protein kinase activity K13582,K13924 - 2.1.1.80,3.1.1.61 2.649e-233 762.0
TLS2_k127_4681460_1 Protein of unknown function (DUF1587) - - - 0.00000000000000000000000000003576 126.0
TLS2_k127_4689539_0 tail sheath protein - - - 5.506e-263 846.0
TLS2_k127_4689539_1 ABC transporter, transmembrane K11085 - - 3.839e-258 810.0
TLS2_k127_4689539_2 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 586.0
TLS2_k127_4689539_3 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 459.0
TLS2_k127_4689539_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000001409 179.0
TLS2_k127_4689539_5 peroxiredoxin activity - - - 0.00000000000000000000000006253 116.0
TLS2_k127_4689539_7 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000009854 96.0
TLS2_k127_4695477_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.215e-242 759.0
TLS2_k127_4695477_1 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 472.0
TLS2_k127_4695477_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005961 288.0
TLS2_k127_4695477_3 Pyridoxamine 5'-phosphate oxidase like - - - 0.0000000000000000000000000000000000000000000000000000001317 198.0
TLS2_k127_4695477_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000003224 150.0
TLS2_k127_4695477_5 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000000000000005997 139.0
TLS2_k127_4695477_6 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000911 120.0
TLS2_k127_470310_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 401.0
TLS2_k127_470310_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000001876 173.0
TLS2_k127_470310_2 PIN domain - - - 0.00000000000000000000000000000008157 132.0
TLS2_k127_470310_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000999 98.0
TLS2_k127_4708106_0 Peptidase S46 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 376.0
TLS2_k127_4708106_1 PFAM Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000009244 208.0
TLS2_k127_4708106_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000002792 87.0
TLS2_k127_4711485_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 329.0
TLS2_k127_4711485_1 Enoyl-(Acyl carrier protein) reductase K00059,K22185 - 1.1.1.100,1.1.1.175 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 290.0
TLS2_k127_4711485_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000001044 113.0
TLS2_k127_4713922_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 2.577e-199 637.0
TLS2_k127_4713922_1 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 327.0
TLS2_k127_4713922_2 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004747 250.0
TLS2_k127_4713922_3 - - - - 0.000000000000000000000003424 103.0
TLS2_k127_4713922_4 - - - - 0.000000000000000001239 89.0
TLS2_k127_472057_0 Glycosyltransferase family 28 C-terminal domain K03715 - 2.4.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 449.0
TLS2_k127_472057_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 395.0
TLS2_k127_472057_2 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 362.0
TLS2_k127_472057_3 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 322.0
TLS2_k127_472057_4 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 304.0
TLS2_k127_472057_5 - - - - 0.0000000000000000000000000000000000000000000002045 175.0
TLS2_k127_472057_6 ArgK protein K07588 - - 0.00000000000000000000000000000000000000006388 160.0
TLS2_k127_472057_7 - - - - 0.000000000000000000000000000000000000009872 151.0
TLS2_k127_472057_8 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000001133 95.0
TLS2_k127_472057_9 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000003873 55.0
TLS2_k127_4735605_0 Carboxypeptidase regulatory-like domain - - - 1.598e-278 897.0
TLS2_k127_4735605_1 Carboxypeptidase regulatory-like domain - - - 2.77e-272 875.0
TLS2_k127_4735605_10 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003692 264.0
TLS2_k127_4735605_11 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000002077 236.0
TLS2_k127_4735605_12 Bacterial pre-peptidase C-terminal domain - - - 0.0000000000000000000000000000000000007953 160.0
TLS2_k127_4735605_13 2-oxopent-4-enoate hydratase activity - - - 0.0000000000000000000000000000000001615 142.0
TLS2_k127_4735605_15 Sigma-70 region 2 K03088 - - 0.000000000000000000000001549 110.0
TLS2_k127_4735605_16 repeat-containing protein - - - 0.000000000000000002201 97.0
TLS2_k127_4735605_17 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000002716 81.0
TLS2_k127_4735605_18 Anti-sigma factor - - - 0.0000000004926 73.0
TLS2_k127_4735605_19 COG0457 FOG TPR repeat - - - 0.0001025 54.0
TLS2_k127_4735605_2 Carboxypeptidase regulatory-like domain - - - 2.571e-229 752.0
TLS2_k127_4735605_3 PFAM Bacterial Ig-like domain (group 2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 558.0
TLS2_k127_4735605_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 461.0
TLS2_k127_4735605_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 430.0
TLS2_k127_4735605_6 4-amino-4-deoxy-L-arabinose transferase activity K16648 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 422.0
TLS2_k127_4735605_7 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 366.0
TLS2_k127_4735605_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 311.0
TLS2_k127_4735605_9 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 331.0
TLS2_k127_4736145_0 Belongs to the IlvD Edd family - - - 5.431e-292 903.0
TLS2_k127_4736145_1 TonB-dependent siderophore receptor K16091 - - 1.537e-218 705.0
TLS2_k127_4736145_10 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000000001982 157.0
TLS2_k127_4736145_11 iron dependent repressor K01356,K03709 - 3.4.21.88 0.0000000000000000000000000000005077 123.0
TLS2_k127_4736145_12 membrane protein of uknown function UCP014873 - - - 0.00001821 53.0
TLS2_k127_4736145_2 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 445.0
TLS2_k127_4736145_3 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 417.0
TLS2_k127_4736145_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 370.0
TLS2_k127_4736145_5 Alanine racemase, N-terminal domain K18425,K19967 - 4.1.2.42,4.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 293.0
TLS2_k127_4736145_6 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000864 258.0
TLS2_k127_4736145_7 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.00000000000000000000000000000000000000000000000000000000000128 219.0
TLS2_k127_4736145_8 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000000000000006128 166.0
TLS2_k127_4736145_9 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000008357 158.0
TLS2_k127_473651_0 Transglutaminase/protease-like homologues K01406 - 3.4.24.40 0.000000000005482 76.0
TLS2_k127_473651_1 - - - - 0.000008327 50.0
TLS2_k127_473651_2 HDOD domain - - - 0.0001453 51.0
TLS2_k127_4744339_0 Carboxypeptidase regulatory-like domain - - - 0.0 1140.0
TLS2_k127_4744339_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 3.357e-247 770.0
TLS2_k127_4744339_10 Uncharacterised protein family (UPF0175) - - - 0.000000000000000075 84.0
TLS2_k127_4744339_11 phenazine biosynthesis protein PhzF family - - - 0.0000000000000001024 80.0
TLS2_k127_4744339_13 - - - - 0.00000000008065 72.0
TLS2_k127_4744339_14 chaperone-mediated protein complex assembly - - - 0.0000001856 60.0
TLS2_k127_4744339_15 Putative Flp pilus-assembly TadE/G-like - - - 0.000006883 58.0
TLS2_k127_4744339_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 2.944e-200 631.0
TLS2_k127_4744339_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 527.0
TLS2_k127_4744339_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00322,K00382 - 1.6.1.1,1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 504.0
TLS2_k127_4744339_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001692 287.0
TLS2_k127_4744339_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000001221 190.0
TLS2_k127_4744339_7 PFAM TadE family protein - - - 0.00000000000000000000000000004993 122.0
TLS2_k127_4744339_8 contains PIN domain - - - 0.00000000000000000000000009793 112.0
TLS2_k127_4744339_9 - - - - 0.00000000000000000000002093 102.0
TLS2_k127_4746399_0 PFAM SNF2-related protein - - - 1.472e-262 822.0
TLS2_k127_4746399_1 SWIM zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 290.0
TLS2_k127_4746399_2 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000447 42.0
TLS2_k127_4773454_0 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 472.0
TLS2_k127_4773454_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 373.0
TLS2_k127_4773454_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 290.0
TLS2_k127_4773454_3 peroxiredoxin activity K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000003495 199.0
TLS2_k127_4773454_4 Transglutaminase/protease-like homologues - - - 0.000005545 57.0
TLS2_k127_4788184_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1262.0
TLS2_k127_4788184_1 Transglycosylase - - - 3.051e-300 953.0
TLS2_k127_4788184_2 Predicted Permease Membrane Region K07085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 501.0
TLS2_k127_4788184_3 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 486.0
TLS2_k127_4788184_4 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 455.0
TLS2_k127_4788184_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000009308 139.0
TLS2_k127_478858_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 394.0
TLS2_k127_478858_1 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 282.0
TLS2_k127_478858_2 PQQ-like domain - - - 0.0000000000000000000000000000000000000000002276 168.0
TLS2_k127_4790337_0 Putative glutamine amidotransferase - - - 1.56e-265 837.0
TLS2_k127_4790337_1 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 510.0
TLS2_k127_4790337_10 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000002163 162.0
TLS2_k127_4790337_11 Protein kinase domain K12132 - 2.7.11.1 0.00000004381 65.0
TLS2_k127_4790337_2 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 502.0
TLS2_k127_4790337_3 PFAM AP endonuclease family 2 C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 474.0
TLS2_k127_4790337_4 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 414.0
TLS2_k127_4790337_5 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 370.0
TLS2_k127_4790337_6 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 353.0
TLS2_k127_4790337_7 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000005839 203.0
TLS2_k127_4790337_8 Amidase - - - 0.0000000000000000000000000000000000000000000001745 175.0
TLS2_k127_4790337_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000002708 168.0
TLS2_k127_479480_0 Cytochrome c - - - 0.0 1518.0
TLS2_k127_479480_1 TIGRFAM malto-oligosyltrehalose trehalohydrolase K00700 - 2.4.1.18 0.0 1062.0
TLS2_k127_479480_10 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 404.0
TLS2_k127_479480_11 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 391.0
TLS2_k127_479480_12 PFAM Adenosine AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 351.0
TLS2_k127_479480_13 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 337.0
TLS2_k127_479480_14 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 323.0
TLS2_k127_479480_15 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000941 266.0
TLS2_k127_479480_16 - - - - 0.000000000000000000000000000000000000000000000000001028 192.0
TLS2_k127_479480_18 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000008094 189.0
TLS2_k127_479480_19 DinB family - - - 0.0000000000000000000000000000000000002872 146.0
TLS2_k127_479480_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1058.0
TLS2_k127_479480_21 PFAM DinB family protein - - - 0.00000000000000000000006617 104.0
TLS2_k127_479480_22 COGs COG1487 nucleic acid-binding protein contains PIN domain K18828 - - 0.000000000000000002729 90.0
TLS2_k127_479480_23 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000002765 75.0
TLS2_k127_479480_25 GTP binding - - - 0.000007146 49.0
TLS2_k127_479480_26 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.00001661 47.0
TLS2_k127_479480_27 - - - - 0.00008979 50.0
TLS2_k127_479480_3 dihydroxy-acid dehydratase activity K01687,K22186 - 4.2.1.82,4.2.1.9 1.245e-257 811.0
TLS2_k127_479480_4 Protein of unknown function (DUF1552) - - - 3.584e-245 762.0
TLS2_k127_479480_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.483e-240 759.0
TLS2_k127_479480_6 Flavin containing amine oxidoreductase - - - 6.891e-240 751.0
TLS2_k127_479480_7 NhaP-type Na H and K H - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 572.0
TLS2_k127_479480_8 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 458.0
TLS2_k127_479480_9 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 409.0
TLS2_k127_4797577_0 PFAM type II secretion system protein E K02283 - - 3.283e-199 629.0
TLS2_k127_4797577_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 347.0
TLS2_k127_4797577_2 type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002631 278.0
TLS2_k127_4797577_3 type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008749 268.0
TLS2_k127_4797577_4 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000001176 175.0
TLS2_k127_4837026_0 Thioredoxin-like K04084 - 1.8.1.8 1.993e-218 694.0
TLS2_k127_4837026_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 2.953e-205 652.0
TLS2_k127_4837026_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 480.0
TLS2_k127_4837026_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 457.0
TLS2_k127_4837026_4 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 363.0
TLS2_k127_4837026_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 294.0
TLS2_k127_4837026_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000006907 209.0
TLS2_k127_4837026_7 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000001302 151.0
TLS2_k127_4837026_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000001324 134.0
TLS2_k127_4837026_9 Ribosomal L32p protein family K02911 - - 0.000000000000000000000008353 101.0
TLS2_k127_4841886_0 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000006972 173.0
TLS2_k127_4841886_1 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000007839 119.0
TLS2_k127_4841886_2 - - - - 0.000000000000000008197 85.0
TLS2_k127_484858_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 571.0
TLS2_k127_484858_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 552.0
TLS2_k127_484858_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 505.0
TLS2_k127_484858_3 MFP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 426.0
TLS2_k127_484858_4 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 310.0
TLS2_k127_484858_5 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001245 267.0
TLS2_k127_484858_7 ABC transporter K02003 - - 0.0000000000000002657 79.0
TLS2_k127_4858461_0 Amidase K01426 - 3.5.1.4 2.14e-257 801.0
TLS2_k127_4858461_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 417.0
TLS2_k127_4858461_2 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 340.0
TLS2_k127_4858461_3 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000001314 171.0
TLS2_k127_4871212_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 567.0
TLS2_k127_4871212_1 Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 435.0
TLS2_k127_4880347_0 Protein of unknown function (DUF1501) - - - 6.3e-220 702.0
TLS2_k127_4880347_1 Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 551.0
TLS2_k127_4880347_10 FCD - - - 0.0000000000000000000000000000000000004632 147.0
TLS2_k127_4880347_11 Putative esterase - - - 0.00000000000000000000000000000000004936 150.0
TLS2_k127_4880347_12 Transcriptional regulator K02529 - - 0.0000000000000000000000000001549 128.0
TLS2_k127_4880347_13 Thioredoxin-like K04084 - 1.8.1.8 0.000000000000003283 78.0
TLS2_k127_4880347_14 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.000000002999 68.0
TLS2_k127_4880347_15 Serine hydrolase involved in the detoxification of formaldehyde K01181 - 3.2.1.8 0.000001749 55.0
TLS2_k127_4880347_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 566.0
TLS2_k127_4880347_3 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 393.0
TLS2_k127_4880347_4 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 349.0
TLS2_k127_4880347_5 COG1413 FOG HEAT repeat K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 306.0
TLS2_k127_4880347_6 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006402 277.0
TLS2_k127_4880347_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000003392 244.0
TLS2_k127_4880347_8 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000001282 249.0
TLS2_k127_4880347_9 - - - - 0.0000000000000000000000000000000000000000000000000000000007771 207.0
TLS2_k127_490311_0 LmbE homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002548 290.0
TLS2_k127_490311_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000001269 240.0
TLS2_k127_490311_2 PhoD-like phosphatase - - - 0.00000000000000000000000000000000000000000000000001604 195.0
TLS2_k127_4931622_0 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 297.0
TLS2_k127_4931622_1 Inositol monophosphatase K01092,K05602,K18649 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008424 275.0
TLS2_k127_4931622_2 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008849 253.0
TLS2_k127_4931622_3 SRP54-type protein, GTPase domain K02404 - - 0.000000000000000000000000000000000000000000000002642 188.0
TLS2_k127_4931622_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000008176 168.0
TLS2_k127_4931622_5 protein histidine kinase activity K06375 - - 0.000000000000000000000000317 115.0
TLS2_k127_4931622_6 - - - - 0.00000000000000000000344 101.0
TLS2_k127_4931622_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000008636 72.0
TLS2_k127_4933902_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1394.0
TLS2_k127_4933902_1 PFAM Cytochrome b b6 domain - - - 7.588e-199 641.0
TLS2_k127_4933902_10 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002112 246.0
TLS2_k127_4933902_11 Domain of unknown function (DUF4403) - - - 0.0000000000000000000000000000000003503 147.0
TLS2_k127_4933902_12 2 iron, 2 sulfur cluster binding - - - 0.000000000000000000000000000000002821 134.0
TLS2_k127_4933902_13 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000001216 134.0
TLS2_k127_4933902_14 YwiC-like protein - - - 0.0000448 54.0
TLS2_k127_4933902_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 557.0
TLS2_k127_4933902_3 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 488.0
TLS2_k127_4933902_4 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 477.0
TLS2_k127_4933902_5 Domain of unknown function (DUF3471) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 355.0
TLS2_k127_4933902_6 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 282.0
TLS2_k127_4933902_7 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000184 266.0
TLS2_k127_4933902_8 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001845 278.0
TLS2_k127_4933902_9 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000004594 259.0
TLS2_k127_4937206_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 469.0
TLS2_k127_4937206_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 463.0
TLS2_k127_4937206_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 441.0
TLS2_k127_4937206_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 415.0
TLS2_k127_4937206_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 282.0
TLS2_k127_4937206_5 positive regulation of growth rate - - - 0.000000000000000000000000000000000000000000000000001864 185.0
TLS2_k127_4937206_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000017 118.0
TLS2_k127_4947920_0 Alpha/beta-hydrolase family N-terminus - - - 7.216e-199 629.0
TLS2_k127_4947920_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 352.0
TLS2_k127_4947920_2 lactoylglutathione lyase activity K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000003606 246.0
TLS2_k127_4961917_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1415.0
TLS2_k127_4961917_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 509.0
TLS2_k127_4961917_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 472.0
TLS2_k127_4961917_3 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 412.0
TLS2_k127_4961917_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 310.0
TLS2_k127_4961917_5 D-isomer specific 2-hydroxyacid dehydrogenase K16843 - 1.1.1.310 0.0000000000000000000000000000000000000000000000000000000002599 207.0
TLS2_k127_4961917_6 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000006735 164.0
TLS2_k127_4961917_7 Cupin domain - - - 0.00000000000000000000000000000000002751 146.0
TLS2_k127_4971294_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 592.0
TLS2_k127_4971294_1 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 379.0
TLS2_k127_4978372_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 377.0
TLS2_k127_4978372_2 Tetratricopeptide repeat - - - 0.000000000000000703 83.0
TLS2_k127_4986496_0 - - - - 5.113e-246 775.0
TLS2_k127_4986496_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 482.0
TLS2_k127_4986496_2 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 436.0
TLS2_k127_4986496_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000474 201.0
TLS2_k127_4986496_4 Dystroglycan-type cadherin-like domains. - - - 0.00000000000000000000000000000000000000006406 171.0
TLS2_k127_4986496_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000008576 106.0
TLS2_k127_4986496_6 cytochrome C peroxidase - - - 0.000000000000000009281 91.0
TLS2_k127_4986496_7 PFAM NHL repeat containing protein - - - 0.000000004284 69.0
TLS2_k127_4987995_0 anaphase-promoting complex binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 485.0
TLS2_k127_4987995_1 anaphase-promoting complex binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 383.0
TLS2_k127_4987995_2 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 355.0
TLS2_k127_5015938_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000004275 108.0
TLS2_k127_5015938_1 Carboxypeptidase regulatory-like domain - - - 0.00001602 57.0
TLS2_k127_5021242_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 592.0
TLS2_k127_5021242_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000008133 249.0
TLS2_k127_5026098_0 PQQ enzyme repeat K00117 - 1.1.5.2 1.611e-284 890.0
TLS2_k127_5026098_1 PFAM Sulfatase K01130 - 3.1.6.1 2.393e-207 661.0
TLS2_k127_5026098_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 562.0
TLS2_k127_5026098_3 PFAM aldo keto reductase - - - 0.000000000000002971 76.0
TLS2_k127_5027694_0 Helicase conserved C-terminal domain K10843 - 3.6.4.12 8.312e-204 653.0
TLS2_k127_5027694_1 SPTR Alr4702 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 595.0
TLS2_k127_5027694_2 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 314.0
TLS2_k127_5027694_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000003063 207.0
TLS2_k127_5027694_4 Protein of unknown function (DUF1648) - - - 0.000000000000000000005109 106.0
TLS2_k127_5027694_5 Protein of unknown function (DUF433) - - - 0.000000000000003727 79.0
TLS2_k127_5027694_6 - - - - 0.00000004314 55.0
TLS2_k127_5033782_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 301.0
TLS2_k127_5033782_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001663 274.0
TLS2_k127_5048327_0 response to abiotic stimulus K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 582.0
TLS2_k127_5048327_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 511.0
TLS2_k127_5048327_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 340.0
TLS2_k127_5048327_3 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 321.0
TLS2_k127_5048327_4 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000001438 168.0
TLS2_k127_5048327_5 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000002876 138.0
TLS2_k127_5053679_0 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001949 288.0
TLS2_k127_5053679_1 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000173 47.0
TLS2_k127_5066265_0 Protein of unknown function (DUF1553) - - - 0.0 1086.0
TLS2_k127_5066265_1 Protein of unknown function (DUF1501) - - - 3.601e-244 784.0
TLS2_k127_5066265_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000003007 168.0
TLS2_k127_5073266_0 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 454.0
TLS2_k127_5073266_1 PFAM Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 324.0
TLS2_k127_5073266_2 pfam nipsnap - - - 0.000000000000000000000000000000000000000000000000000000000000000521 228.0
TLS2_k127_5073266_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000002056 191.0
TLS2_k127_5073266_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000001792 134.0
TLS2_k127_5073266_5 - - - - 0.00000000000000000000000000000004617 130.0
TLS2_k127_5073266_6 response regulator K07689 - - 0.00002632 56.0
TLS2_k127_5080079_0 MacB-like periplasmic core domain - - - 0.0 1022.0
TLS2_k127_5080079_1 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001877 277.0
TLS2_k127_5080079_10 DNA-templated transcription, initiation K03088 - - 0.0000003972 54.0
TLS2_k127_5080079_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008166 257.0
TLS2_k127_5080079_3 PFAM tRNA rRNA methyltransferase, SpoU K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004862 250.0
TLS2_k127_5080079_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001537 248.0
TLS2_k127_5080079_5 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000004007 200.0
TLS2_k127_5080079_6 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000000907 197.0
TLS2_k127_5080079_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000001681 177.0
TLS2_k127_5080079_8 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000008116 157.0
TLS2_k127_5080079_9 - - - - 0.000000000002254 79.0
TLS2_k127_5107102_0 AbgT putative transporter family K12942 - - 9.174e-212 672.0
TLS2_k127_5107102_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans - - - 5.598e-204 644.0
TLS2_k127_5107102_10 Domain of unknown function (DUF378) - - - 0.000000000000000001188 88.0
TLS2_k127_5107102_11 Nucleotidyltransferase domain K07075 - - 0.0000000000000001148 83.0
TLS2_k127_5107102_12 COGs COG2361 conserved - - - 0.00000000000261 68.0
TLS2_k127_5107102_13 Belongs to the 'phage' integrase family - - - 0.0000001465 53.0
TLS2_k127_5107102_14 COGs COG2361 conserved - - - 0.00001102 52.0
TLS2_k127_5107102_2 COG0433 Predicted ATPase K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 578.0
TLS2_k127_5107102_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 311.0
TLS2_k127_5107102_4 PFAM beta-Ig-H3 fasciclin - - - 0.0000000000000000000000000000000000000000000000000000000007404 205.0
TLS2_k127_5107102_5 - - - - 0.000000000000000000000000000000000000000000000000000000001127 206.0
TLS2_k127_5107102_6 PFAM Mandelate racemase muconate lactonizing - - - 0.0000000000000000000000000000000000000000009746 170.0
TLS2_k127_5107102_7 COGs COG2380 conserved - - - 0.00000000000000000000000000000000000000001132 168.0
TLS2_k127_5107102_8 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000003711 143.0
TLS2_k127_5153192_0 mandelate racemase muconate lactonizing K08323 GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872 4.2.1.8 1.262e-197 624.0
TLS2_k127_5153192_1 peptidase dimerisation domain protein - - - 2.811e-194 615.0
TLS2_k127_5153192_10 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000006032 74.0
TLS2_k127_5153192_2 ethanolamine kinase activity K04343,K07251,K18844 - 2.7.1.72,2.7.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006878 280.0
TLS2_k127_5153192_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.000000000000000000000000000000000000000000000000000000000000001515 235.0
TLS2_k127_5153192_4 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000003598 186.0
TLS2_k127_5153192_5 Haem-degrading - - - 0.00000000000000000000000000000000000000006388 159.0
TLS2_k127_5153192_6 addiction module antidote protein HigA - - - 0.0000000000000000000000000000000000000001079 152.0
TLS2_k127_5153192_7 Plasmid maintenance system killer K07334 - - 0.000000000000000000000000000000005425 129.0
TLS2_k127_5153192_8 antisigma factor binding K04749 - - 0.0000000000000000001881 100.0
TLS2_k127_5153192_9 PEP-CTERM motif - - - 0.000000000001572 76.0
TLS2_k127_5175779_0 glucuronate isomerase K01812 - 5.3.1.12 8.298e-204 644.0
TLS2_k127_5175779_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 549.0
TLS2_k127_5175779_10 crispr-associated protein K09127 - - 0.00000000000000000000000000000000000000000000000001762 193.0
TLS2_k127_5175779_11 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000007755 168.0
TLS2_k127_5175779_12 CRISPR-associated protein (Cas_Cas02710) - - - 0.000000000000000000000000000000000000000001692 171.0
TLS2_k127_5175779_13 Thioesterase K01075,K07107 - 3.1.2.23 0.00000000000000000000008265 113.0
TLS2_k127_5175779_14 Protein of unknown function (DUF3311) - - - 0.00000000002342 68.0
TLS2_k127_5175779_2 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 454.0
TLS2_k127_5175779_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 380.0
TLS2_k127_5175779_4 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 366.0
TLS2_k127_5175779_5 RAMP protein Cmr6 K19142 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 354.0
TLS2_k127_5175779_6 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 294.0
TLS2_k127_5175779_7 TIGRFAM CRISPR-associated protein Cas10 Cmr2, subtype III-B K19076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004612 276.0
TLS2_k127_5175779_8 Crispr-associated ramp protein, Cmr4 family K09000 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002534 247.0
TLS2_k127_5175779_9 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0033890,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000002575 229.0
TLS2_k127_5181596_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 9.461e-216 692.0
TLS2_k127_5181596_1 TIGRFAM ATP-dependent DNA helicase, RecQ family K03169,K03654 - 3.6.4.12,5.99.1.2 4.272e-199 629.0
TLS2_k127_5181596_2 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 475.0
TLS2_k127_5181596_3 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000825 276.0
TLS2_k127_5181596_4 Plasmid stabilization protein ParE K19092 - - 0.00000000000000000000002234 105.0
TLS2_k127_5181596_5 Putative restriction endonuclease - - - 0.00000000000000000001036 98.0
TLS2_k127_5181596_6 - - - - 0.0000000000000007926 84.0
TLS2_k127_5181596_7 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.00000000000004565 78.0
TLS2_k127_5188583_0 PFAM ABC transporter K11085 - - 2.486e-234 740.0
TLS2_k127_5188583_1 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 562.0
TLS2_k127_5188583_10 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001458 239.0
TLS2_k127_5188583_11 GDSL-like Lipase/Acylhydrolase K12686 - - 0.00000000000000000000000000000000000000000000001369 185.0
TLS2_k127_5188583_12 PIN domain - - - 0.000000000000000000000000000000000000000000001107 168.0
TLS2_k127_5188583_13 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000003986 97.0
TLS2_k127_5188583_14 - - - - 0.000000000000000002352 97.0
TLS2_k127_5188583_15 - - - - 0.00000000000000001109 86.0
TLS2_k127_5188583_16 Trm112p-like protein K09791 - - 0.000000000000000039 81.0
TLS2_k127_5188583_17 prlF antitoxin for toxin YhaV_toxin - - - 0.00007865 48.0
TLS2_k127_5188583_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 509.0
TLS2_k127_5188583_3 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 391.0
TLS2_k127_5188583_4 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 354.0
TLS2_k127_5188583_5 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 346.0
TLS2_k127_5188583_6 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 308.0
TLS2_k127_5188583_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003025 284.0
TLS2_k127_5188583_8 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001405 280.0
TLS2_k127_5188583_9 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000001832 252.0
TLS2_k127_5190600_0 N-Acyl-D-aspartate D-glutamate deacylase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 381.0
TLS2_k127_5190600_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000005308 105.0
TLS2_k127_5190600_2 - - - - 0.0000000000002333 82.0
TLS2_k127_5196754_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 616.0
TLS2_k127_5196754_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000003704 134.0
TLS2_k127_519687_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1075.0
TLS2_k127_519687_1 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 364.0
TLS2_k127_519687_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000009537 204.0
TLS2_k127_519687_4 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000009158 186.0
TLS2_k127_519687_5 Cytochrome c K00413 - - 0.0000000000000000000000001487 116.0
TLS2_k127_519687_6 SIR2-like domain - - - 0.0000000000000000004493 88.0
TLS2_k127_519687_7 PFAM DNA methylase N-4 N-6 domain protein K07316 - 2.1.1.72 0.0000002191 57.0
TLS2_k127_5207306_0 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits K00966,K00992 - 2.7.7.13,2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004382 278.0
TLS2_k127_5207306_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000005861 213.0
TLS2_k127_5207306_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K07102 - 2.7.1.221 0.0000000000000000000008028 96.0
TLS2_k127_5215797_0 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 475.0
TLS2_k127_5215797_1 TOBE domain K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 421.0
TLS2_k127_5215797_2 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 381.0
TLS2_k127_5215797_3 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 310.0
TLS2_k127_5215797_4 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000001893 184.0
TLS2_k127_5215797_5 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000001152 111.0
TLS2_k127_5216515_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005041 284.0
TLS2_k127_5229225_0 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 405.0
TLS2_k127_5229225_1 Malate/L-lactate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003877 262.0
TLS2_k127_5229225_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000004549 225.0
TLS2_k127_5229225_3 metal cluster binding K06940 - - 0.000000000000000000000000000000000000001263 152.0
TLS2_k127_5231549_0 Cytochrome c - - - 7.802e-304 958.0
TLS2_k127_5231549_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 365.0
TLS2_k127_5237387_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 1.911e-196 617.0
TLS2_k127_5237387_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 496.0
TLS2_k127_52508_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.279e-300 939.0
TLS2_k127_52508_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 2.692e-248 792.0
TLS2_k127_52508_10 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 488.0
TLS2_k127_52508_11 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 429.0
TLS2_k127_52508_12 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 431.0
TLS2_k127_52508_13 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 412.0
TLS2_k127_52508_14 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 374.0
TLS2_k127_52508_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 376.0
TLS2_k127_52508_16 peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 374.0
TLS2_k127_52508_17 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 366.0
TLS2_k127_52508_18 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 322.0
TLS2_k127_52508_19 TIGRFAM TonB family K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 314.0
TLS2_k127_52508_2 amino acid K03294 - - 1.537e-237 743.0
TLS2_k127_52508_20 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 316.0
TLS2_k127_52508_21 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007391 286.0
TLS2_k127_52508_22 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001802 250.0
TLS2_k127_52508_24 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000000003084 191.0
TLS2_k127_52508_25 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000001261 199.0
TLS2_k127_52508_26 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000007222 201.0
TLS2_k127_52508_27 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000002578 162.0
TLS2_k127_52508_28 PFAM Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000006121 151.0
TLS2_k127_52508_29 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000003086 144.0
TLS2_k127_52508_3 PA domain - - - 3.823e-216 687.0
TLS2_k127_52508_30 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000006595 148.0
TLS2_k127_52508_31 PFAM SpoVT AbrB - - - 0.000000000000000000000000000001276 122.0
TLS2_k127_52508_32 cellular response to DNA damage stimulus K07340 - - 0.00000000000000000000000000004141 123.0
TLS2_k127_52508_33 Preprotein translocase, YajC K03210 - - 0.0000000000000000000002788 100.0
TLS2_k127_52508_34 TIGRFAM methionine biosynthesis protein MetW - - - 0.000006437 49.0
TLS2_k127_52508_36 Proton-conducting membrane transporter - - - 0.00001324 51.0
TLS2_k127_52508_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.113e-215 682.0
TLS2_k127_52508_5 Protein of unknown function (DUF1501) - - - 3.563e-194 620.0
TLS2_k127_52508_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 576.0
TLS2_k127_52508_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 572.0
TLS2_k127_52508_8 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 560.0
TLS2_k127_52508_9 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 529.0
TLS2_k127_5284569_0 DEAD DEAH box K03724 - - 0.0 1279.0
TLS2_k127_5284569_1 PFAM FAD linked oxidase domain protein - - - 2.836e-272 882.0
TLS2_k127_5284569_10 aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000183 280.0
TLS2_k127_5284569_11 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000002369 241.0
TLS2_k127_5284569_12 Tellurite resistance protein tehB K03647,K16868 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.265 0.00000000000000000000000000000000000000000000000000000001647 201.0
TLS2_k127_5284569_13 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000254 196.0
TLS2_k127_5284569_14 Uncharacterised protein family (UPF0158) - - - 0.0000000000000000000000000000009768 128.0
TLS2_k127_5284569_16 chorismate lyase activity - - - 0.0000000000000000001117 98.0
TLS2_k127_5284569_2 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 595.0
TLS2_k127_5284569_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 537.0
TLS2_k127_5284569_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 514.0
TLS2_k127_5284569_5 PFAM Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 465.0
TLS2_k127_5284569_6 PFAM Alcohol dehydrogenase zinc-binding domain protein K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 393.0
TLS2_k127_5284569_7 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 387.0
TLS2_k127_5284569_8 Dicarboxylate carrier - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 364.0
TLS2_k127_5284569_9 Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 352.0
TLS2_k127_5294979_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 505.0
TLS2_k127_5294979_1 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 505.0
TLS2_k127_5294979_10 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008887 295.0
TLS2_k127_5294979_11 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000006169 235.0
TLS2_k127_5294979_12 Ham1 family K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000007873 216.0
TLS2_k127_5294979_13 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000001451 202.0
TLS2_k127_5294979_14 AAA domain - - - 0.00000000000000000000000000000000000000000003951 166.0
TLS2_k127_5294979_15 - - - - 0.00000000000000000000000000000000000000003896 160.0
TLS2_k127_5294979_16 transcriptional regulator PadR family - - - 0.00000000000000000000000000000000001242 138.0
TLS2_k127_5294979_17 Low molecular weight phosphatase family - - - 0.0000000000000000000003212 100.0
TLS2_k127_5294979_18 positive regulation of catalytic activity in other organism involved in symbiotic interaction K14861 GO:0000922,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005813,GO:0005815,GO:0005819,GO:0005856,GO:0007346,GO:0008150,GO:0015630,GO:0019899,GO:0019900,GO:0030496,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044430,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051233,GO:0051726,GO:0065007,GO:0072686,GO:0097431,GO:1990023 - 0.00000000000000001065 98.0
TLS2_k127_5294979_19 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000004507 72.0
TLS2_k127_5294979_2 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 461.0
TLS2_k127_5294979_3 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 452.0
TLS2_k127_5294979_4 Belongs to the DapA family K01714,K21062 - 3.5.4.22,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 421.0
TLS2_k127_5294979_5 Belongs to the proline racemase family K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 423.0
TLS2_k127_5294979_6 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 418.0
TLS2_k127_5294979_7 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 414.0
TLS2_k127_5294979_8 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 415.0
TLS2_k127_5294979_9 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 349.0
TLS2_k127_5300464_0 Methyltransferase domain - - - 3.158e-211 667.0
TLS2_k127_5300464_1 Cation transport protein K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 497.0
TLS2_k127_5300464_10 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000004078 108.0
TLS2_k127_5300464_11 Protein of unknown function (DUF433) - - - 0.00000000000000000000005649 106.0
TLS2_k127_5300464_2 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 471.0
TLS2_k127_5300464_3 TrkA-C domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 293.0
TLS2_k127_5300464_4 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000001688 239.0
TLS2_k127_5300464_5 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000005841 234.0
TLS2_k127_5300464_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000002211 155.0
TLS2_k127_5300464_7 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000008503 154.0
TLS2_k127_5300464_8 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000002717 131.0
TLS2_k127_5300464_9 - - - - 0.00000000000000000000000000001483 121.0
TLS2_k127_5309195_0 PFAM Type II secretion system protein E K02652 - - 3.612e-237 748.0
TLS2_k127_5309195_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 578.0
TLS2_k127_5309195_10 SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000003467 203.0
TLS2_k127_5309195_11 PFAM response regulator receiveR - - - 0.0000000000000000000000000000000000000000000000001124 184.0
TLS2_k127_5309195_12 Protein of unknown function (DUF3800) - - - 0.0000000000000000000000000000000001954 139.0
TLS2_k127_5309195_13 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000001804 131.0
TLS2_k127_5309195_14 Protein of unknown function (DUF3467) K06603 - - 0.0000000000000000000000000000003408 128.0
TLS2_k127_5309195_15 Tetratricopeptide repeat - - - 0.0000000000000000000000001379 123.0
TLS2_k127_5309195_17 Transcriptional regulator, DeoR family K21601 - - 0.0000004342 58.0
TLS2_k127_5309195_18 peptidase M48, Ste24p - - - 0.00001684 58.0
TLS2_k127_5309195_19 Protein of unknown function (DUF3800) - - - 0.0000413 53.0
TLS2_k127_5309195_2 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 513.0
TLS2_k127_5309195_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 473.0
TLS2_k127_5309195_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 398.0
TLS2_k127_5309195_5 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 390.0
TLS2_k127_5309195_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 336.0
TLS2_k127_5309195_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 314.0
TLS2_k127_5309195_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001307 232.0
TLS2_k127_5309195_9 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000008299 207.0
TLS2_k127_5323358_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 535.0
TLS2_k127_5323358_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009202 458.0
TLS2_k127_5323358_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 389.0
TLS2_k127_532920_0 Carboxypeptidase regulatory-like domain - - - 1.82e-321 1017.0
TLS2_k127_532920_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.14e-312 970.0
TLS2_k127_532920_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009764 407.0
TLS2_k127_532920_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 289.0
TLS2_k127_532920_4 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003241 253.0
TLS2_k127_532920_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001024 153.0
TLS2_k127_5334367_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 459.0
TLS2_k127_5334367_1 - - - - 0.000000000000005552 86.0
TLS2_k127_5337634_0 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 413.0
TLS2_k127_5337634_1 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000000000005164 173.0
TLS2_k127_5337918_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 402.0
TLS2_k127_5337918_1 Carboxypeptidase regulatory-like domain - - - 0.0007487 45.0
TLS2_k127_5368904_0 Carboxypeptidase regulatory-like domain - - - 0.0 1122.0
TLS2_k127_5368904_1 ASPIC and UnbV - - - 4.054e-263 822.0
TLS2_k127_5368904_10 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000001618 138.0
TLS2_k127_5368904_11 Protein of unknown function (DUF2905) - - - 0.0000000000000001141 81.0
TLS2_k127_5368904_12 Protein of unknown function (DUF1501) - - - 0.0000000000000004539 78.0
TLS2_k127_5368904_13 Cytochrome C' - - - 0.0009234 48.0
TLS2_k127_5368904_2 Protein of unknown function (DUF1595) - - - 2.484e-215 697.0
TLS2_k127_5368904_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 520.0
TLS2_k127_5368904_4 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 524.0
TLS2_k127_5368904_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 471.0
TLS2_k127_5368904_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 472.0
TLS2_k127_5368904_7 Pirin C-terminal cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 319.0
TLS2_k127_5368904_8 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002693 258.0
TLS2_k127_5368904_9 TIR domain - - - 0.00000000000000000000000000000000000005339 153.0
TLS2_k127_5370424_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 7.61e-257 827.0
TLS2_k127_5370424_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000001587 108.0
TLS2_k127_5388792_0 PFAM WD40-like beta Propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001122 300.0
TLS2_k127_5388792_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000002143 183.0
TLS2_k127_5391876_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1648.0
TLS2_k127_5391876_1 serine-type peptidase activity K06978,K21105 - 3.1.1.102 2.076e-204 670.0
TLS2_k127_5391876_10 Iron-binding zinc finger CDGSH type K05710 - - 0.0000000000000000000002113 98.0
TLS2_k127_5391876_12 Carboxypeptidase regulatory-like domain - - - 0.00000002256 58.0
TLS2_k127_5391876_13 transcriptional regulator, SARP family - - - 0.00000006682 60.0
TLS2_k127_5391876_14 Helix-turn-helix domain - - - 0.000008878 51.0
TLS2_k127_5391876_2 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 546.0
TLS2_k127_5391876_3 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 433.0
TLS2_k127_5391876_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 383.0
TLS2_k127_5391876_5 -O-antigen K02847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 381.0
TLS2_k127_5391876_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 300.0
TLS2_k127_5391876_8 Endonuclease I - - - 0.000000000000000000000000000000000000000000000000000000000000000003251 256.0
TLS2_k127_5391876_9 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000003441 205.0
TLS2_k127_5413081_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 554.0
TLS2_k127_5413081_1 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 384.0
TLS2_k127_5413081_10 self proteolysis K01406 - 3.4.24.40 0.0000000000002685 79.0
TLS2_k127_5413081_11 self proteolysis K01406 - 3.4.24.40 0.000000000001252 69.0
TLS2_k127_5413081_2 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 375.0
TLS2_k127_5413081_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 308.0
TLS2_k127_5413081_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006757 273.0
TLS2_k127_5413081_5 Integral membrane protein (intg_mem_TP0381) - - - 0.000000000000000000000000000000000000000000000000000000000000007316 229.0
TLS2_k127_5413081_6 regulatory protein, MerR - - - 0.00000000000000000000000000000000001487 139.0
TLS2_k127_5413081_7 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000003865 121.0
TLS2_k127_5413081_8 Tetratricopeptide repeat - - - 0.000000000000000000000004675 109.0
TLS2_k127_5413081_9 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000005477 83.0
TLS2_k127_541945_0 Peptidase family M1 domain K01256,K08776 - 3.4.11.2 5.094e-204 665.0
TLS2_k127_541945_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.083e-201 634.0
TLS2_k127_541945_10 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 288.0
TLS2_k127_541945_11 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005651 279.0
TLS2_k127_541945_12 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000007997 173.0
TLS2_k127_541945_13 PFAM Prenyltransferase squalene oxidase K06015 - 3.5.1.81 0.00000000000000000000000000000000000002788 156.0
TLS2_k127_541945_14 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000936 152.0
TLS2_k127_541945_15 molybdenum cofactor guanylyltransferase activity K03637,K03752,K13818 - 2.7.7.77,4.6.1.17 0.00000000000000000000000000000002969 133.0
TLS2_k127_541945_16 PFAM PemK-like protein K07171 - - 0.00000000000000000004174 92.0
TLS2_k127_541945_17 KR domain K00059 - 1.1.1.100 0.000000000000000001051 95.0
TLS2_k127_541945_18 phosphorelay signal transduction system - - - 0.0000000000000005506 84.0
TLS2_k127_541945_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 618.0
TLS2_k127_541945_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 510.0
TLS2_k127_541945_4 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 448.0
TLS2_k127_541945_5 pfam abc K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 384.0
TLS2_k127_541945_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 372.0
TLS2_k127_541945_7 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 363.0
TLS2_k127_541945_8 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 338.0
TLS2_k127_541945_9 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 328.0
TLS2_k127_5439318_0 TonB-dependent receptor - - - 0.0 1190.0
TLS2_k127_5439318_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 316.0
TLS2_k127_5439318_10 - - - - 0.00000000000000004364 87.0
TLS2_k127_5439318_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004592 283.0
TLS2_k127_5439318_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000001293 243.0
TLS2_k127_5439318_4 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000796 184.0
TLS2_k127_5439318_5 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000005796 168.0
TLS2_k127_5439318_6 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000006917 156.0
TLS2_k127_5439318_7 hydroperoxide reductase activity - - - 0.0000000000000000000000000000000000002399 141.0
TLS2_k127_5439318_8 hydroperoxide reductase activity - - - 0.00000000000000000000000000000000001141 138.0
TLS2_k127_5439318_9 Iodothyronine deiodinase - - - 0.0000000000000000000000000000000001137 136.0
TLS2_k127_5448501_0 WD40-like Beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 519.0
TLS2_k127_5448501_1 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 334.0
TLS2_k127_5448501_10 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000007635 129.0
TLS2_k127_5448501_11 GYD domain - - - 0.0000000000000000000000000007632 116.0
TLS2_k127_5448501_12 COG0668 Small-conductance mechanosensitive channel - - - 0.0000006149 59.0
TLS2_k127_5448501_2 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 310.0
TLS2_k127_5448501_3 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000003092 263.0
TLS2_k127_5448501_4 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000019 256.0
TLS2_k127_5448501_5 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003056 252.0
TLS2_k127_5448501_6 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000007469 204.0
TLS2_k127_5448501_7 TIGRFAM TonB family K03832 - - 0.000000000000000000000000000000000000000000000001316 184.0
TLS2_k127_5448501_8 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000008902 178.0
TLS2_k127_5448501_9 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000000000000004592 150.0
TLS2_k127_5467523_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 5.931e-315 986.0
TLS2_k127_5467523_1 Cytochrome c - - - 1.697e-294 932.0
TLS2_k127_5467523_2 Protein of unknown function (DUF1501) - - - 9.235e-195 624.0
TLS2_k127_5467523_3 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 370.0
TLS2_k127_5467523_4 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 324.0
TLS2_k127_5467523_5 domain protein - - - 0.00000000000001221 87.0
TLS2_k127_5473827_0 Glutamate-ammonia ligase adenylyltransferase K00982 - 2.7.7.42,2.7.7.89 1.659e-299 947.0
TLS2_k127_5473827_1 AcrB/AcrD/AcrF family K03296 - - 1.917e-291 919.0
TLS2_k127_5473827_2 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.462e-278 865.0
TLS2_k127_5473827_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.284e-196 623.0
TLS2_k127_5473827_4 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 417.0
TLS2_k127_5473827_5 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 374.0
TLS2_k127_5473827_6 K -dependent Na Ca exchanger K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 339.0
TLS2_k127_5473827_7 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000002716 247.0
TLS2_k127_5473827_8 - K21449 - - 0.00000000000000000000000000000000000000004283 167.0
TLS2_k127_5473827_9 PFAM helix-turn-helix HxlR type - - - 0.00000000000000000000000000000000004817 138.0
TLS2_k127_5481322_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit K05568 - - 7.319e-200 632.0
TLS2_k127_5484756_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 349.0
TLS2_k127_5484756_1 membrane-bound metal-dependent hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 311.0
TLS2_k127_5484756_2 self proteolysis K01406 - 3.4.24.40 0.0000000000000000000000000000000000000000000006105 183.0
TLS2_k127_5484756_3 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0002544 44.0
TLS2_k127_5484811_0 ASPIC and UnbV - - - 1.274e-233 734.0
TLS2_k127_5484811_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 478.0
TLS2_k127_5484811_2 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 424.0
TLS2_k127_5484811_3 self proteolysis K01406 - 3.4.24.40 0.00000000000000000000000000000000000000000005863 164.0
TLS2_k127_5484811_4 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000000000000000000000003358 130.0
TLS2_k127_5484811_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000008475 53.0
TLS2_k127_54938_0 Multicopper oxidase - - - 7.76e-242 756.0
TLS2_k127_54938_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.045e-233 731.0
TLS2_k127_54938_10 tetratricopeptide repeat - - - 0.00000002414 66.0
TLS2_k127_54938_11 Resolvase, N terminal domain - - - 0.0000001113 63.0
TLS2_k127_54938_12 Addiction module antitoxin, RelB DinJ family K07473 - - 0.000001617 57.0
TLS2_k127_54938_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 444.0
TLS2_k127_54938_3 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 373.0
TLS2_k127_54938_4 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 339.0
TLS2_k127_54938_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003005 292.0
TLS2_k127_54938_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000778 261.0
TLS2_k127_54938_7 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000002292 250.0
TLS2_k127_54938_9 Multicopper oxidase - - - 0.0000000000000000000000000000000000158 141.0
TLS2_k127_5499452_0 kinase activity K01007 - 2.7.9.2 4.238e-259 825.0
TLS2_k127_5499452_1 amine dehydrogenase activity K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 632.0
TLS2_k127_5499452_2 Histidine kinase internal region K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 491.0
TLS2_k127_5499452_3 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K22319 - 6.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 503.0
TLS2_k127_5499452_4 Protein of unknown function (DUF3419) K13622 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 440.0
TLS2_k127_5499452_5 transferase activity, transferring acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 300.0
TLS2_k127_5499452_6 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001342 278.0
TLS2_k127_5499452_7 dolichyl monophosphate biosynthetic process K00981,K18678 - 2.7.1.182,2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000136 276.0
TLS2_k127_5499452_8 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000004647 257.0
TLS2_k127_5499452_9 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.0000000000000000000000000000000000000000000000000000000002585 205.0
TLS2_k127_5511553_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1104.0
TLS2_k127_5511553_1 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 353.0
TLS2_k127_5529578_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 5.943e-287 914.0
TLS2_k127_5529578_1 Cytochrome b(C-terminal)/b6/petD K00412 - - 8.093e-205 652.0
TLS2_k127_5529578_10 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000001929 196.0
TLS2_k127_5529578_11 Rieske [2Fe-2S] domain K03886 - - 0.0000000000000000000000000000000000000000000000000002368 190.0
TLS2_k127_5529578_12 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14392 - - 0.000000000000000000000000000000000000000000000000001513 194.0
TLS2_k127_5529578_13 - - - - 0.00000000000000000000000000000000000000000002072 173.0
TLS2_k127_5529578_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.0000000000000000000000000000000000000000001011 180.0
TLS2_k127_5529578_15 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000003417 152.0
TLS2_k127_5529578_16 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000009996 138.0
TLS2_k127_5529578_17 Winged helix-turn helix - - - 0.0000000000000000000000000001072 123.0
TLS2_k127_5529578_18 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000001175 118.0
TLS2_k127_5529578_19 Hypothetical glycosyl hydrolase 6 - - - 0.0000000000000000000002198 104.0
TLS2_k127_5529578_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 615.0
TLS2_k127_5529578_20 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000001027 94.0
TLS2_k127_5529578_21 dextransucrase activity - - - 0.000000000000000002481 93.0
TLS2_k127_5529578_22 Hypothetical glycosyl hydrolase 6 - - - 0.00000000000000003179 90.0
TLS2_k127_5529578_3 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 566.0
TLS2_k127_5529578_4 binding domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 552.0
TLS2_k127_5529578_5 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 456.0
TLS2_k127_5529578_6 inositol 2-dehydrogenase activity K18106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 436.0
TLS2_k127_5529578_7 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 390.0
TLS2_k127_5529578_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 378.0
TLS2_k127_5529578_9 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001907 238.0
TLS2_k127_5536578_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 517.0
TLS2_k127_5537881_0 FtsX-like permease family K02004 - - 5.902e-271 856.0
TLS2_k127_5537881_1 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 343.0
TLS2_k127_5537881_2 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000108 262.0
TLS2_k127_5537881_3 ATPases associated with a variety of cellular activities K02003 - - 0.00000001131 56.0
TLS2_k127_5549174_0 - - - - 4.885e-264 837.0
TLS2_k127_5549174_1 Alpha-2-Macroglobulin K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000002708 227.0
TLS2_k127_5571354_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 329.0
TLS2_k127_5571354_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 301.0
TLS2_k127_5571354_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000004041 246.0
TLS2_k127_5571354_3 Dienelactone hydrolase family - - - 0.00000000000000000000000000009591 118.0
TLS2_k127_5571354_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000006071 107.0
TLS2_k127_5576500_0 crispr-associated protein K07016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 465.0
TLS2_k127_5576500_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 423.0
TLS2_k127_5576500_10 Domain of unknown function (DUF4160) - - - 0.0000000000000004003 79.0
TLS2_k127_5576500_11 ligase activity - - - 0.0000002556 64.0
TLS2_k127_5576500_2 RAMP superfamily K09002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 411.0
TLS2_k127_5576500_3 RAMP superfamily K19140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 415.0
TLS2_k127_5576500_4 CRISPR-associated RAMP protein, Csm4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 314.0
TLS2_k127_5576500_5 Pfam:DUF310 - - - 0.00000000000000000000000000000000000000000000000000000000004732 208.0
TLS2_k127_5576500_6 PFAM amine oxidase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000006539 210.0
TLS2_k127_5576500_7 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000004606 188.0
TLS2_k127_5576500_8 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000009025 151.0
TLS2_k127_5576500_9 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000000001091 127.0
TLS2_k127_5623586_0 transport - - - 0.0 1354.0
TLS2_k127_5623586_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 374.0
TLS2_k127_5623586_2 - - - - 0.0000000000000000774 92.0
TLS2_k127_5623586_3 - - - - 0.00001427 48.0
TLS2_k127_5627082_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 383.0
TLS2_k127_5627082_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 311.0
TLS2_k127_5627082_2 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 328.0
TLS2_k127_5627082_3 Adenylate cyclase - - - 0.000000000000000000001394 111.0
TLS2_k127_5632745_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239,K00244,K00278 GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 1.3.5.1,1.3.5.4,1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 531.0
TLS2_k127_5632745_1 teichoic acid transport K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 321.0
TLS2_k127_5632745_2 metal cluster binding - - - 0.00000000000000000000000000000000000000000000000000485 188.0
TLS2_k127_5632745_3 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 0.000000000000000000000000000005774 119.0
TLS2_k127_5642816_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 454.0
TLS2_k127_5642816_1 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 359.0
TLS2_k127_5642816_2 protein domain associated with - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000827 275.0
TLS2_k127_5642816_3 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000003816 210.0
TLS2_k127_5642816_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000004492 183.0
TLS2_k127_5642816_5 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000001235 108.0
TLS2_k127_5642816_6 PFAM Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000001615 96.0
TLS2_k127_5642816_7 BNR repeat-containing family member - - - 0.00000001747 56.0
TLS2_k127_5656716_0 GMC oxidoreductase - - - 2.217e-256 804.0
TLS2_k127_5656716_1 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000000000000000000003977 135.0
TLS2_k127_5656716_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000007397 77.0
TLS2_k127_5660022_0 Peptidase M1, membrane alanine aminopeptidase - - - 3.433e-249 784.0
TLS2_k127_5660022_1 amine dehydrogenase activity K14647,K21449 - - 2.052e-230 747.0
TLS2_k127_5660022_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 462.0
TLS2_k127_5660022_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002263 237.0
TLS2_k127_5660022_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000001507 225.0
TLS2_k127_5660022_5 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.000000000000000000000000003987 111.0
TLS2_k127_5661799_0 Carboxypeptidase regulatory-like domain - - - 8.194e-313 992.0
TLS2_k127_5661799_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.968e-298 926.0
TLS2_k127_5661799_2 Cys Met metabolism K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 559.0
TLS2_k127_5661799_3 hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 323.0
TLS2_k127_5661799_4 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000002681 227.0
TLS2_k127_5661799_5 Pfam:N_methyl_2 - - - 0.000000000000000000000000000000000000000000000000000001256 195.0
TLS2_k127_5661799_6 methyltransferase - - - 0.00000000000000000000000001378 119.0
TLS2_k127_5661799_7 Tetratricopeptide repeat - - - 0.00000001986 68.0
TLS2_k127_5663378_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1099.0
TLS2_k127_5663378_1 Carboxypeptidase regulatory-like domain - - - 8.76e-303 960.0
TLS2_k127_5663378_10 aldo keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003325 245.0
TLS2_k127_5663378_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000005706 219.0
TLS2_k127_5663378_12 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.0000000000000000000000000000000000000000000000004146 178.0
TLS2_k127_5663378_13 AntiSigma factor - - - 0.0000000000000000000000000000000000000006672 164.0
TLS2_k127_5663378_14 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000004745 140.0
TLS2_k127_5663378_15 PFAM Rv0623 family protein transcription factor K19687 - - 0.00000000000000000000000000005097 119.0
TLS2_k127_5663378_16 Protein of unknown function (DUF433) - - - 0.000000000000000000000008685 106.0
TLS2_k127_5663378_17 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000003737 113.0
TLS2_k127_5663378_18 - - - - 0.000000000000000001618 88.0
TLS2_k127_5663378_19 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000007267 89.0
TLS2_k127_5663378_2 alpha beta - - - 3.026e-231 741.0
TLS2_k127_5663378_22 phosphorelay signal transduction system - - - 0.0006609 49.0
TLS2_k127_5663378_23 cytochrome c - - - 0.0007176 49.0
TLS2_k127_5663378_3 COG3119 Arylsulfatase A K01138 - - 4.395e-200 638.0
TLS2_k127_5663378_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 6.406e-198 630.0
TLS2_k127_5663378_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 562.0
TLS2_k127_5663378_6 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 331.0
TLS2_k127_5663378_7 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 292.0
TLS2_k127_5663378_8 FMN binding K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000006919 269.0
TLS2_k127_5663378_9 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006325 259.0
TLS2_k127_5665710_0 metal ion transport K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 486.0
TLS2_k127_5665710_1 Phenylalanine-4-hydroxylase K00500 GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 464.0
TLS2_k127_5665710_10 - - - - 0.000000000000000000000000000000000000000000000000000006818 198.0
TLS2_k127_5665710_11 Leucine Rich repeat - - - 0.0000000000000000000000000000000733 134.0
TLS2_k127_5665710_12 Pfam Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000005775 128.0
TLS2_k127_5665710_13 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000000000000000000001012 117.0
TLS2_k127_5665710_14 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000001015 100.0
TLS2_k127_5665710_15 Protein involved in outer membrane biogenesis - - - 0.00007111 51.0
TLS2_k127_5665710_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 441.0
TLS2_k127_5665710_3 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 421.0
TLS2_k127_5665710_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 405.0
TLS2_k127_5665710_5 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 368.0
TLS2_k127_5665710_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 375.0
TLS2_k127_5665710_7 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 300.0
TLS2_k127_5665710_8 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 297.0
TLS2_k127_5665710_9 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001662 273.0
TLS2_k127_5669257_0 TonB-dependent receptor - - - 0.0 1237.0
TLS2_k127_5669257_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 5.328e-313 966.0
TLS2_k127_5669257_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002815 271.0
TLS2_k127_5669257_11 Carbohydrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000003151 242.0
TLS2_k127_5669257_12 Phage Tail Collar - - - 0.0000000000000000000000000000000000000000000000000000000004093 206.0
TLS2_k127_5669257_13 alpha-ribazole phosphatase activity K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.000000000000000000000000000003499 131.0
TLS2_k127_5669257_15 FR47-like protein - - - 0.00000000000000000006359 96.0
TLS2_k127_5669257_16 - - - - 0.000001027 55.0
TLS2_k127_5669257_17 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00003186 46.0
TLS2_k127_5669257_2 ASPIC and UnbV - - - 9.35e-201 639.0
TLS2_k127_5669257_3 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 539.0
TLS2_k127_5669257_4 gluconolactonase activity K07004,K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 515.0
TLS2_k127_5669257_5 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 361.0
TLS2_k127_5669257_6 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 347.0
TLS2_k127_5669257_7 ABC-type glycine betaine transport system K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001832 290.0
TLS2_k127_5669257_8 PFAM ABC transporter related K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003188 279.0
TLS2_k127_5669257_9 glycine betaine transport K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001061 272.0
TLS2_k127_567413_0 electron transfer activity K02305,K08738 - - 1.581e-262 841.0
TLS2_k127_567413_1 Dehydrogenase K00117 - 1.1.5.2 6.011e-214 682.0
TLS2_k127_567413_10 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000000001393 170.0
TLS2_k127_567413_11 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000000000000000001439 162.0
TLS2_k127_567413_12 protein carbamoylation K04656,K05927 - 1.12.5.1 0.0000000000000000001323 93.0
TLS2_k127_567413_13 Cupin 2, conserved barrel domain protein - - - 0.00000000000000003315 85.0
TLS2_k127_567413_14 antitoxin component of a - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.0000000000000009024 81.0
TLS2_k127_567413_15 BNR repeat-like domain K05989 - 3.2.1.40 0.00000003937 65.0
TLS2_k127_567413_16 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.00003046 49.0
TLS2_k127_567413_2 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 578.0
TLS2_k127_567413_3 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 499.0
TLS2_k127_567413_4 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 485.0
TLS2_k127_567413_5 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 378.0
TLS2_k127_567413_6 energy transducer activity K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 385.0
TLS2_k127_567413_7 mandelate racemase muconate lactonizing K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 322.0
TLS2_k127_567413_8 PFAM Surface antigen variable number K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001239 281.0
TLS2_k127_567413_9 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000002183 197.0
TLS2_k127_5679901_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 460.0
TLS2_k127_5679901_1 Hexosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000956 342.0
TLS2_k127_5679901_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000000000000000000001983 176.0
TLS2_k127_5679901_3 Uncharacterised nucleotidyltransferase - - - 0.0000000000009093 75.0
TLS2_k127_5687656_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 4.417e-221 694.0
TLS2_k127_5687656_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 501.0
TLS2_k127_5687656_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001803 229.0
TLS2_k127_5687656_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000003361 77.0
TLS2_k127_5689238_0 56kDa selenium binding protein (SBP56) K17285 - - 6.151e-274 852.0
TLS2_k127_5689238_1 PFAM Organic solvent tolerance protein K04744 - - 3.678e-269 850.0
TLS2_k127_5689238_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 308.0
TLS2_k127_5689238_3 dihydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006022 247.0
TLS2_k127_5689238_4 excinuclease ABC activity - - - 0.000000000000000000000000000000000000000008661 160.0
TLS2_k127_5689238_5 - - - - 0.00000000000000000000000000002551 129.0
TLS2_k127_5689238_7 pfam rdd - - - 0.000000000000000000000003114 114.0
TLS2_k127_5689238_8 - - - - 0.0000000000000000241 83.0
TLS2_k127_5689238_9 ASPIC and UnbV - - - 0.00001976 48.0
TLS2_k127_5693534_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1309.0
TLS2_k127_5693534_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.365e-242 758.0
TLS2_k127_5693534_11 Transcriptional regulator K05799 - - 0.00000000000000000000000000000000000000000000000000000000001536 216.0
TLS2_k127_5693534_12 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000001337 202.0
TLS2_k127_5693534_13 Thioredoxin - - - 0.0000000000000000000000000000000000000000003481 171.0
TLS2_k127_5693534_14 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000000000000000000000000000000000009682 162.0
TLS2_k127_5693534_15 Transposase - - - 0.00000000000000000000000000000001612 139.0
TLS2_k127_5693534_16 - - - - 0.0000000000000000000006546 100.0
TLS2_k127_5693534_17 deoxyhypusine monooxygenase activity K03301 - - 0.000000000000005477 89.0
TLS2_k127_5693534_18 - - - - 0.00000000002432 68.0
TLS2_k127_5693534_19 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000005591 64.0
TLS2_k127_5693534_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 7.332e-220 688.0
TLS2_k127_5693534_20 Carboxypeptidase regulatory-like domain - - - 0.000001546 59.0
TLS2_k127_5693534_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 8.805e-205 648.0
TLS2_k127_5693534_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 9.676e-204 644.0
TLS2_k127_5693534_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 468.0
TLS2_k127_5693534_6 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 433.0
TLS2_k127_5693534_7 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 363.0
TLS2_k127_5693534_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000102 301.0
TLS2_k127_5693534_9 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000005819 237.0
TLS2_k127_5700100_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 588.0
TLS2_k127_5700100_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 500.0
TLS2_k127_5700100_10 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 357.0
TLS2_k127_5700100_11 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 352.0
TLS2_k127_5700100_12 PFAM Formylglycine-generating sulfatase enzyme K03496,K12055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 335.0
TLS2_k127_5700100_14 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009126 276.0
TLS2_k127_5700100_15 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000003111 243.0
TLS2_k127_5700100_17 - - - - 0.00000000000000000000000000000000007355 145.0
TLS2_k127_5700100_18 SEFIR domain - - - 0.0000000000000000000001663 107.0
TLS2_k127_5700100_19 Protein of unknown function (DUF433) - - - 0.0000000000000000000253 93.0
TLS2_k127_5700100_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 499.0
TLS2_k127_5700100_20 Large extracellular alpha-helical protein K12287 - - 0.000000000000000003682 100.0
TLS2_k127_5700100_21 phosphorelay signal transduction system - - - 0.00000000000002118 80.0
TLS2_k127_5700100_22 Peptidoglycan-binding domain 1 protein K01185,K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.17,3.5.1.28 0.0000000000002262 76.0
TLS2_k127_5700100_23 - - - - 0.00000000002067 66.0
TLS2_k127_5700100_24 PFAM Membrane protein of K08972 - - 0.00000000004917 68.0
TLS2_k127_5700100_26 COG3794 Plastocyanin - - - 0.00005604 53.0
TLS2_k127_5700100_28 secreted Zn-dependent protease - - - 0.0007184 52.0
TLS2_k127_5700100_29 Belongs to the peptidase S8 family - - - 0.000748 53.0
TLS2_k127_5700100_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 481.0
TLS2_k127_5700100_4 Peptidase, M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 466.0
TLS2_k127_5700100_5 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 443.0
TLS2_k127_5700100_6 protocatechuate 3,4-dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 447.0
TLS2_k127_5700100_7 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 389.0
TLS2_k127_5700100_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 378.0
TLS2_k127_5700100_9 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 361.0
TLS2_k127_5707580_0 Baseplate J-like protein - - - 3.581e-237 759.0
TLS2_k127_5707580_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 612.0
TLS2_k127_5707580_10 amidohydrolase - - - 0.0000008514 52.0
TLS2_k127_5707580_2 Baseplate J-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 584.0
TLS2_k127_5707580_3 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 552.0
TLS2_k127_5707580_4 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 514.0
TLS2_k127_5707580_5 Late control gene D protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 448.0
TLS2_k127_5707580_6 Rhs element vgr protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003094 241.0
TLS2_k127_5707580_7 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.000000000000000000000000000000000000000000000000671 186.0
TLS2_k127_5707580_8 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000000000000000002482 155.0
TLS2_k127_5707580_9 - - - - 0.00000000000000000000000000002015 124.0
TLS2_k127_5709376_0 MacB-like periplasmic core domain - - - 2.78e-321 1011.0
TLS2_k127_5709376_1 Iron-containing alcohol dehydrogenase K11173 - 1.1.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 549.0
TLS2_k127_5709376_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 415.0
TLS2_k127_5709376_3 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000000000000000000000000000000006165 183.0
TLS2_k127_5709376_4 PFAM sulfatase - - - 0.0000000000000000000007888 96.0
TLS2_k127_5709376_5 - - - - 0.000124 51.0
TLS2_k127_5709746_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1095.0
TLS2_k127_5709746_1 Belongs to the UbiD family K03182 - 4.1.1.98 1.73e-247 774.0
TLS2_k127_5709746_10 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 320.0
TLS2_k127_5709746_11 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 319.0
TLS2_k127_5709746_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 291.0
TLS2_k127_5709746_13 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001108 297.0
TLS2_k127_5709746_14 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004337 281.0
TLS2_k127_5709746_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001349 251.0
TLS2_k127_5709746_16 lactoylglutathione lyase activity K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000002491 243.0
TLS2_k127_5709746_17 efflux transmembrane transporter activity K15725 - - 0.000000000000000000000000000000000000000000000000000000000000007528 231.0
TLS2_k127_5709746_18 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000001482 219.0
TLS2_k127_5709746_19 NikR C terminal nickel binding domain K07722 - - 0.0000000000000000000000000000000000000000000000000000000000001058 214.0
TLS2_k127_5709746_2 Hypothetical glycosyl hydrolase 6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 569.0
TLS2_k127_5709746_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000007595 230.0
TLS2_k127_5709746_21 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000001587 213.0
TLS2_k127_5709746_22 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000005411 182.0
TLS2_k127_5709746_23 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002388 175.0
TLS2_k127_5709746_25 - - - - 0.000000000000000000000000000000000000006641 149.0
TLS2_k127_5709746_26 PIN domain - - - 0.00000000000000000000000000000000001011 140.0
TLS2_k127_5709746_27 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000002 102.0
TLS2_k127_5709746_28 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000004345 85.0
TLS2_k127_5709746_3 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 507.0
TLS2_k127_5709746_31 Peptidase U62 modulator of DNA gyrase K03592 - - 0.00004961 52.0
TLS2_k127_5709746_4 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 477.0
TLS2_k127_5709746_5 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 473.0
TLS2_k127_5709746_6 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 444.0
TLS2_k127_5709746_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 445.0
TLS2_k127_5709746_9 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 338.0
TLS2_k127_5719107_0 Belongs to the glycosyl hydrolase 57 family - - - 3.424e-280 882.0
TLS2_k127_5719107_1 Prokaryotic cytochrome b561 - - - 1.847e-202 646.0
TLS2_k127_5719107_2 carboxylic acid catabolic process K12661 - 4.2.1.90 3.254e-196 619.0
TLS2_k127_5719107_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 561.0
TLS2_k127_5719107_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000002838 232.0
TLS2_k127_5719107_5 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700,K01236 - 2.4.1.18,3.2.1.141 0.0000000000000000000000000000002653 130.0
TLS2_k127_5719107_6 PFAM ATP-binding region ATPase domain protein - - - 0.0000000001276 67.0
TLS2_k127_5719107_7 monooxygenase activity - - - 0.000000001322 63.0
TLS2_k127_5726655_0 Carboxypeptidase regulatory-like domain - - - 0.0 1250.0
TLS2_k127_5726655_1 transport - - - 1.36e-310 992.0
TLS2_k127_5726655_10 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000293 237.0
TLS2_k127_5726655_11 - - - - 0.000000000000000000000000000000000000000000000000000000000001499 221.0
TLS2_k127_5726655_12 Pfam:DUF162 K00782 - - 0.000000000000000000000000000000000000000000000000000000003583 206.0
TLS2_k127_5726655_13 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000162 202.0
TLS2_k127_5726655_14 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000001203 189.0
TLS2_k127_5726655_15 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000000000003769 167.0
TLS2_k127_5726655_2 cluster binding protein K18929 - - 1.15e-200 638.0
TLS2_k127_5726655_3 Peptidase, M16 K07263 - - 1.831e-194 628.0
TLS2_k127_5726655_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 410.0
TLS2_k127_5726655_5 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 343.0
TLS2_k127_5726655_6 macromolecule localization K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 316.0
TLS2_k127_5726655_7 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 294.0
TLS2_k127_5726655_8 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 293.0
TLS2_k127_5726655_9 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002543 269.0
TLS2_k127_573518_0 Putative phage tail protein - - - 0.0 1296.0
TLS2_k127_573518_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 513.0
TLS2_k127_573518_10 - - - - 0.0000000000000000000000000000000000000000001411 165.0
TLS2_k127_573518_11 ribonuclease activity - - - 0.00000000000000000000000000000000004702 141.0
TLS2_k127_573518_12 - - - - 0.00000000000000000000000000115 117.0
TLS2_k127_573518_13 - - - - 0.000000000000000000000000001326 121.0
TLS2_k127_573518_14 - - - - 0.00000000000000000000008083 107.0
TLS2_k127_573518_15 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000002366 102.0
TLS2_k127_573518_16 Conserved hypothetical protein 2217 (DUF2460) - - - 0.000000000000000000000406 99.0
TLS2_k127_573518_18 - - - - 0.0000000000000001344 85.0
TLS2_k127_573518_19 - - - - 0.000000000000006625 79.0
TLS2_k127_573518_2 P22 coat protein - gene protein 5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 479.0
TLS2_k127_573518_21 Transposase K07484 - - 0.00000000624 64.0
TLS2_k127_573518_22 - - - - 0.00000003278 62.0
TLS2_k127_573518_3 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 466.0
TLS2_k127_573518_4 Elongator protein 3, MiaB family, Radical SAM K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 417.0
TLS2_k127_573518_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 389.0
TLS2_k127_573518_6 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 340.0
TLS2_k127_573518_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 346.0
TLS2_k127_573518_8 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 305.0
TLS2_k127_573518_9 - - - - 0.0000000000000000000000000000000000000000000002588 176.0
TLS2_k127_5737977_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 610.0
TLS2_k127_5737977_1 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 524.0
TLS2_k127_5737977_2 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 331.0
TLS2_k127_5738420_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 505.0
TLS2_k127_5738420_1 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 469.0
TLS2_k127_5738420_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 446.0
TLS2_k127_5738420_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000009757 154.0
TLS2_k127_5760618_0 Sodium:sulfate symporter transmembrane region K03319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 569.0
TLS2_k127_5760618_1 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004904 262.0
TLS2_k127_5760618_2 pfam abc K02065 - - 0.00000001577 66.0
TLS2_k127_5768335_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0 1675.0
TLS2_k127_5771266_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 566.0
TLS2_k127_5771266_1 SMART Phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 487.0
TLS2_k127_5771266_2 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 347.0
TLS2_k127_5771266_3 WD40-like Beta Propeller Repeat K01730 - 4.2.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000006259 253.0
TLS2_k127_5771266_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001334 237.0
TLS2_k127_5771266_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000001936 218.0
TLS2_k127_5771266_6 PFAM von Willebrand factor type A - - - 0.000000001069 68.0
TLS2_k127_5793139_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1506.0
TLS2_k127_5793139_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 3.02e-295 938.0
TLS2_k127_5793139_10 uridine kinase K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000003307 169.0
TLS2_k127_5793139_12 signal transduction histidine kinase - - - 0.000005699 56.0
TLS2_k127_5793139_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 426.0
TLS2_k127_5793139_3 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 389.0
TLS2_k127_5793139_4 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 382.0
TLS2_k127_5793139_5 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 314.0
TLS2_k127_5793139_6 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000000000000000000003453 236.0
TLS2_k127_5793139_7 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000001268 246.0
TLS2_k127_5793139_8 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures - - - 0.00000000000000000000000000000000000000000000000000000000000001739 220.0
TLS2_k127_5793139_9 endonuclease activity - - - 0.000000000000000000000000000000000000000000000000000004024 194.0
TLS2_k127_5804778_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000001106 251.0
TLS2_k127_5804778_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000003835 92.0
TLS2_k127_580807_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 603.0
TLS2_k127_580807_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000007408 57.0
TLS2_k127_580807_2 Tetratricopeptide repeat - - - 0.00000109 58.0
TLS2_k127_58173_0 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 508.0
TLS2_k127_58173_1 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 409.0
TLS2_k127_58173_3 - - - - 0.00000000005928 70.0
TLS2_k127_5817763_0 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 8.347e-220 692.0
TLS2_k127_5817763_1 Male sterility protein K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 329.0
TLS2_k127_5817763_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004981 294.0
TLS2_k127_5817763_3 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001825 266.0
TLS2_k127_5829833_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 3.657e-310 978.0
TLS2_k127_5829833_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 440.0
TLS2_k127_5829833_2 Ankyrin repeat - - - 0.00000000000003759 74.0
TLS2_k127_5830498_0 arylsulfatase activity - - - 6.886e-223 702.0
TLS2_k127_5830498_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 396.0
TLS2_k127_5830498_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 385.0
TLS2_k127_5830498_3 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 374.0
TLS2_k127_5830498_4 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000008798 184.0
TLS2_k127_5830498_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000127 153.0
TLS2_k127_5844924_0 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 391.0
TLS2_k127_5844924_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001943 266.0
TLS2_k127_5845936_0 Protein of unknown function (DUF1501) - - - 1.546e-246 768.0
TLS2_k127_5845936_1 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 461.0
TLS2_k127_5845936_2 protein import - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 402.0
TLS2_k127_5845936_3 Plasmid pRiA4b ORF-3-like protein - - - 0.000000000000000000000000000000000000000000004127 174.0
TLS2_k127_5845936_4 Cupin domain - - - 0.00000000000000000000000000000000000000000001457 165.0
TLS2_k127_5845936_5 Planctomycete cytochrome C - - - 0.00000000000000000000000000009549 117.0
TLS2_k127_5849426_0 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 3.208e-214 672.0
TLS2_k127_5849426_1 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 538.0
TLS2_k127_5854873_0 choline dehydrogenase activity K03333 - 1.1.3.6 0.0 1251.0
TLS2_k127_5854873_1 Carboxypeptidase regulatory-like domain - - - 3.817e-275 884.0
TLS2_k127_5854873_10 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000008366 234.0
TLS2_k127_5854873_11 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000139 211.0
TLS2_k127_5854873_12 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000003849 188.0
TLS2_k127_5854873_13 - - - - 0.0000000000000000000000000000000000000000000000002855 190.0
TLS2_k127_5854873_14 Glycosyl transferase, family 2 K01854,K07011 - 5.4.99.9 0.000000000000000000000000000000000000000000000001373 190.0
TLS2_k127_5854873_15 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000000001336 172.0
TLS2_k127_5854873_16 Oxidoreductase FAD NAD(P)-binding domain protein K00351 - 1.6.5.8 0.00000000000000000000000000000000000001348 158.0
TLS2_k127_5854873_17 Rdx family K07401 - - 0.0000000000000000000000000000000003446 136.0
TLS2_k127_5854873_18 PFAM nuclease (SNase domain protein) - - - 0.000000000000000000000000000003053 125.0
TLS2_k127_5854873_19 Belongs to the ompA family K03286 - - 0.0000000000000000000000000001956 116.0
TLS2_k127_5854873_2 Cytochrome c - - - 1.258e-220 702.0
TLS2_k127_5854873_20 von Willebrand factor (vWF) type A domain - - - 0.0000008195 57.0
TLS2_k127_5854873_3 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 612.0
TLS2_k127_5854873_4 COG3119 Arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 587.0
TLS2_k127_5854873_5 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 482.0
TLS2_k127_5854873_6 amidohydrolase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 362.0
TLS2_k127_5854873_7 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 352.0
TLS2_k127_5854873_8 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 318.0
TLS2_k127_5854873_9 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001005 257.0
TLS2_k127_5859703_0 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 453.0
TLS2_k127_5859703_1 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006065 281.0
TLS2_k127_5859703_10 Peptidase M48 - - - 0.00000001146 65.0
TLS2_k127_5859703_11 - - - - 0.000008618 52.0
TLS2_k127_5859703_12 Domain of unknown function (DUF4349) - - - 0.00003926 48.0
TLS2_k127_5859703_2 Doxx family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006318 272.0
TLS2_k127_5859703_3 FtsZ-dependent cytokinesis K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002072 253.0
TLS2_k127_5859703_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000001198 233.0
TLS2_k127_5859703_5 Antitoxin component of a type II toxin-antitoxin (TA) system. Labile antitoxin that binds to the MqsR mRNA interferase toxin and neutralizes its endoribonuclease activity. Overexpression prevents MqsR-mediated cessation of cell growth and inhibition of cell proliferation. Initially reported to act as a cotranscription factor with MqsA. Following further experiments, the MqsR-MqsA complex does not bind DNA and all reported data are actually due to a small fraction of free MqsA alone binding DNA. Addition of MqsR to a preformed MqsA-promoter DNA complex causes dissociation of the MqsA-DNA complex, probably causing derepression of MqsA- repressed transcripts. MqsA binds to 2 palindromes in the promoter region of the mqsRA operon activating its transcription. Binds to other promoters, inducing mcbR and spy and repressing cspD among others. Binds to and represses the rpoS promoter, the master stress regulator, resulting in decreased cyclic-di-GMP, reduced stress resistance, increased cell motility and decreased biofilm formation K13655 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000002754 214.0
TLS2_k127_5859703_6 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000001621 205.0
TLS2_k127_5859703_7 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000002373 159.0
TLS2_k127_5859703_8 Toxic component of a type II toxin-antitoxin (TA) system. Plays a significant role in the control of biofilm formation and induction of persister cells in the presence of antibiotics. An mRNA interferase which has been reported to be translation-independent. It has also been reported to be translation- dependent. Cleavage has been reported to occur on either side of G in the sequence GCU. Also reported to cleave after C in GC(A U) sequences. There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity K13651 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006355,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0032268,GO:0032269,GO:0032879,GO:0034248,GO:0034249,GO:0034641,GO:0040012,GO:0042710,GO:0043170,GO:0043487,GO:0043488,GO:0044010,GO:0044237,GO:0044238,GO:0044764,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051270,GO:0051704,GO:0060255,GO:0061013,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1902679,GO:1903311,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000145,GO:2001141 - 0.000000000000000000000000000000000006214 138.0
TLS2_k127_5859703_9 ribonuclease activity - - - 0.0000000000000000000000000001554 120.0
TLS2_k127_5861587_0 radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 524.0
TLS2_k127_5861587_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 394.0
TLS2_k127_5861587_2 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 304.0
TLS2_k127_5861587_3 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000007514 262.0
TLS2_k127_5861587_4 - - - - 0.00000000000000000000000000000000000000000000000000000001463 208.0
TLS2_k127_5863138_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.315e-277 863.0
TLS2_k127_5863138_1 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 540.0
TLS2_k127_5863138_2 L-seryl-tRNASec selenium transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 492.0
TLS2_k127_5863138_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 408.0
TLS2_k127_5863138_4 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000001202 218.0
TLS2_k127_5889428_0 SPFH Band 7 PHB domain protein K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007103 251.0
TLS2_k127_5889428_1 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000004435 218.0
TLS2_k127_5889428_2 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000132 194.0
TLS2_k127_5892097_0 Carboxypeptidase regulatory-like domain - - - 6.028e-245 788.0
TLS2_k127_5892097_1 mandelate racemase muconate lactonizing K22209 - 4.2.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 496.0
TLS2_k127_5892097_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 415.0
TLS2_k127_5895028_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000007564 239.0
TLS2_k127_5895028_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000001087 111.0
TLS2_k127_5900576_0 Copper amine oxidase, N2 domain K00276 - 1.4.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 566.0
TLS2_k127_5900576_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 436.0
TLS2_k127_5900576_10 domain, Protein - - - 0.000000000000000000000000000000001597 134.0
TLS2_k127_5900576_11 Transglycosylase SLT domain - - - 0.00000000000000000000000000000005884 136.0
TLS2_k127_5900576_12 Flagellar protein FliS K02422 - - 0.0000000000000000000000009873 109.0
TLS2_k127_5900576_13 positive regulation of growth - - - 0.000000000000000000000001087 104.0
TLS2_k127_5900576_14 Domain of unknown function (DUF4926) - - - 0.000000000000000000002283 95.0
TLS2_k127_5900576_15 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000000000008327 85.0
TLS2_k127_5900576_16 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.000000000000001074 80.0
TLS2_k127_5900576_17 - - - - 0.0000000002044 66.0
TLS2_k127_5900576_18 PFAM Flagellar protein FlaG protein K06603 - - 0.00000001684 62.0
TLS2_k127_5900576_2 flagellar basal-body rod protein FlgG K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 390.0
TLS2_k127_5900576_20 Rod binding protein K02395 - - 0.0003146 50.0
TLS2_k127_5900576_3 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002972 253.0
TLS2_k127_5900576_4 basal body rod protein K02391,K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000433 231.0
TLS2_k127_5900576_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000000000000000000000002212 217.0
TLS2_k127_5900576_6 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000000000000000000000000000000000000000002734 209.0
TLS2_k127_5900576_7 SRP54-type protein, GTPase domain K02404 - - 0.000000000000000000000000000000000000000000000000000001369 206.0
TLS2_k127_5900576_8 Chaperone for flagella basal body P-ring formation K02386 - - 0.000000000000000000000000000000000000001595 164.0
TLS2_k127_5900576_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000006912 138.0
TLS2_k127_5922375_0 PFAM TonB-dependent Receptor Plug - - - 0.0 1292.0
TLS2_k127_5922375_1 Surface antigen variable number K07277 - - 0.0 1223.0
TLS2_k127_5922375_10 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000001376 273.0
TLS2_k127_5922375_11 GAF domain - - - 0.000000000000000000000000000000000000001433 151.0
TLS2_k127_5922375_12 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000000000000000002154 142.0
TLS2_k127_5922375_13 CHRD domain - - - 0.00000000000000000000000000000001338 136.0
TLS2_k127_5922375_14 self proteolysis K01406 - 3.4.24.40 0.00000000000000000003912 96.0
TLS2_k127_5922375_17 dihydrofolate reductase activity - - - 0.0000000001824 64.0
TLS2_k127_5922375_18 Transposase - - - 0.00000001764 61.0
TLS2_k127_5922375_19 - - - - 0.000408 52.0
TLS2_k127_5922375_2 Protein of unknown function (DUF1595) - - - 0.0 1059.0
TLS2_k127_5922375_3 Protein of unknown function (DUF1552) - - - 3.305e-236 736.0
TLS2_k127_5922375_4 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 5.942e-207 649.0
TLS2_k127_5922375_5 PhoD-like phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009603 605.0
TLS2_k127_5922375_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 504.0
TLS2_k127_5922375_7 Aldose 1-epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 380.0
TLS2_k127_5922375_8 COG4206 Outer membrane cobalamin receptor protein K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 316.0
TLS2_k127_5922375_9 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000744 286.0
TLS2_k127_5948765_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 454.0
TLS2_k127_5948765_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 436.0
TLS2_k127_5948765_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000002413 173.0
TLS2_k127_5948765_3 YjbR - - - 0.000000000000000000000000000009062 120.0
TLS2_k127_5951273_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 606.0
TLS2_k127_5951273_1 COG3119 Arylsulfatase A K01134 - 3.1.6.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 594.0
TLS2_k127_5951273_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 479.0
TLS2_k127_5951273_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 398.0
TLS2_k127_5951273_4 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000001163 159.0
TLS2_k127_5951273_5 (FHA) domain - - - 0.0000000000000007143 85.0
TLS2_k127_5951273_6 PFAM Resolvase domain - - - 0.00000000003097 67.0
TLS2_k127_595417_0 Phosphate acyltransferases K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 578.0
TLS2_k127_595417_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 502.0
TLS2_k127_595417_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 483.0
TLS2_k127_595417_3 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 450.0
TLS2_k127_595417_4 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 452.0
TLS2_k127_595417_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006828 266.0
TLS2_k127_5967620_0 Protein of unknown function (DUF1501) - - - 5.706e-206 649.0
TLS2_k127_5967620_1 Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 307.0
TLS2_k127_599340_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 502.0
TLS2_k127_599340_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 448.0
TLS2_k127_599340_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 411.0
TLS2_k127_599340_3 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002287 250.0
TLS2_k127_600735_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 619.0
TLS2_k127_600735_1 PFAM Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000007537 209.0
TLS2_k127_6008808_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 431.0
TLS2_k127_6008808_1 formamidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 313.0
TLS2_k127_6008808_2 DinB superfamily - - - 0.000000000000000000000000000002905 127.0
TLS2_k127_6008808_3 PFAM CHAD domain containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000001928 98.0
TLS2_k127_6008808_4 ASPIC and UnbV - - - 0.000000000000005964 82.0
TLS2_k127_6008808_5 Tetratricopeptide repeat - - - 0.00000000000003442 86.0
TLS2_k127_6008808_6 PFAM CHAD domain containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000008219 68.0
TLS2_k127_6009897_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.735e-239 752.0
TLS2_k127_6009897_1 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 375.0
TLS2_k127_6009897_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 355.0
TLS2_k127_6009897_3 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000002078 164.0
TLS2_k127_6009897_4 with different specificities (related to short-chain alcohol K00046 - 1.1.1.69 0.000000000000000000004241 93.0
TLS2_k127_6017326_0 Glycosyl transferases group 1 - - - 1.655e-292 917.0
TLS2_k127_6017326_1 Wzt C-terminal domain K09691 - - 1.191e-197 625.0
TLS2_k127_6017326_2 Belongs to the xylose isomerase family K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 527.0
TLS2_k127_6017326_3 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 489.0
TLS2_k127_6017326_4 extracellular polysaccharide biosynthetic process K00568,K03561,K07011,K20444 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 360.0
TLS2_k127_6028531_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 3.75e-322 1002.0
TLS2_k127_6028531_1 protein synonym multiple resistance and pH homeostasis protein A K05565 - - 5.6e-219 703.0
TLS2_k127_6028531_10 Na+/H+ antiporter subunit K05571 - - 0.0000000000000000000000000001196 123.0
TLS2_k127_6028531_11 Na H antiporter, MnhB K05566 - - 0.0000000000000000000000002495 118.0
TLS2_k127_6028531_12 - - - - 0.00000000000000000001282 93.0
TLS2_k127_6028531_13 Multisubunit Na H antiporter, MnhF subunit K05563,K05570 - - 0.0000000000000000008978 89.0
TLS2_k127_6028531_14 symporter activity - - - 0.000000000008041 66.0
TLS2_k127_6028531_2 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 3.499e-213 696.0
TLS2_k127_6028531_3 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 578.0
TLS2_k127_6028531_4 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 457.0
TLS2_k127_6028531_5 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 439.0
TLS2_k127_6028531_6 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 405.0
TLS2_k127_6028531_7 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 321.0
TLS2_k127_6028531_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000000000001375 141.0
TLS2_k127_6028531_9 Na+/H+ ion antiporter subunit K05562,K05569 - - 0.0000000000000000000000000000001372 126.0
TLS2_k127_6037541_0 Peptidase family M1 domain - - - 1.861e-215 694.0
TLS2_k127_6037541_1 Aminotransferase class I and II K14261 - - 1.287e-197 621.0
TLS2_k127_6037541_10 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006991 252.0
TLS2_k127_6037541_11 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000003419 255.0
TLS2_k127_6037541_12 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000009992 221.0
TLS2_k127_6037541_13 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000006911 181.0
TLS2_k127_6037541_14 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000003706 178.0
TLS2_k127_6037541_15 methyltransferase - - - 0.000000000000000000000000000000000000001287 154.0
TLS2_k127_6037541_16 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000002372 157.0
TLS2_k127_6037541_17 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000002304 131.0
TLS2_k127_6037541_18 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000002362 96.0
TLS2_k127_6037541_19 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000008728 91.0
TLS2_k127_6037541_2 PFAM Xanthine uracil vitamin C permease K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 554.0
TLS2_k127_6037541_20 cellulase activity - - - 0.00000000000002618 78.0
TLS2_k127_6037541_21 pyrroloquinoline quinone binding - - - 0.00000000008998 67.0
TLS2_k127_6037541_22 Domain of unknown function (DUF427) - - - 0.00000001192 64.0
TLS2_k127_6037541_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 449.0
TLS2_k127_6037541_4 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 372.0
TLS2_k127_6037541_5 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 364.0
TLS2_k127_6037541_6 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 325.0
TLS2_k127_6037541_7 - K07039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 309.0
TLS2_k127_6037541_8 cobalamin-transporting ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 292.0
TLS2_k127_6037541_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001405 280.0
TLS2_k127_603793_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 633.0
TLS2_k127_603793_1 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000003067 197.0
TLS2_k127_603793_2 - - - - 0.000155 54.0
TLS2_k127_6076455_0 helicase activity - - - 7.961e-284 894.0
TLS2_k127_6076455_1 ABC transporter K10441,K10545,K10562 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 600.0
TLS2_k127_6076455_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 415.0
TLS2_k127_6076455_3 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000001144 130.0
TLS2_k127_6076455_4 PKD domain containing protein - - - 0.000000000002988 70.0
TLS2_k127_6079212_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008568 272.0
TLS2_k127_6079212_1 Bacterial Ig-like domain (group 2) - - - 0.0000000000000000001274 95.0
TLS2_k127_6079212_2 Transcriptional regulatory protein, C terminal - - - 0.0000003625 52.0
TLS2_k127_6102888_0 Dehydratase large subunit K01699,K06120 - 4.2.1.28,4.2.1.30 1.559e-217 698.0
TLS2_k127_6102888_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 586.0
TLS2_k127_6102888_10 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000001836 223.0
TLS2_k127_6102888_11 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000006736 230.0
TLS2_k127_6102888_12 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000002298 210.0
TLS2_k127_6102888_13 Dehydratase K13919 - 4.2.1.28 0.0000000000000000000000000000000000000000000000001256 201.0
TLS2_k127_6102888_14 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000005694 173.0
TLS2_k127_6102888_15 Radical SAM superfamily K06871 - - 0.00000000000000000000000000000000000000000000001688 194.0
TLS2_k127_6102888_16 - - - - 0.000000000000000000000000000000000000000000001415 178.0
TLS2_k127_6102888_18 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000001734 175.0
TLS2_k127_6102888_19 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000002322 166.0
TLS2_k127_6102888_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 488.0
TLS2_k127_6102888_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000001143 163.0
TLS2_k127_6102888_21 Dehydratase small subunit K13920 - 4.2.1.28 0.00000000000000000000000000000001618 134.0
TLS2_k127_6102888_22 - - - - 0.0000000000000000000000000000007301 130.0
TLS2_k127_6102888_23 radical SAM domain protein K15045 - - 0.0000000000000003645 93.0
TLS2_k127_6102888_24 - - - - 0.000000000000001277 81.0
TLS2_k127_6102888_25 - - - - 0.0000000008996 67.0
TLS2_k127_6102888_26 - - - - 0.00000002667 63.0
TLS2_k127_6102888_28 family 9 - - - 0.0003316 52.0
TLS2_k127_6102888_29 CHAP domain - - - 0.0004358 48.0
TLS2_k127_6102888_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 437.0
TLS2_k127_6102888_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 386.0
TLS2_k127_6102888_5 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 315.0
TLS2_k127_6102888_6 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 306.0
TLS2_k127_6102888_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000338 284.0
TLS2_k127_6102888_8 amine dehydrogenase activity K12287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001554 289.0
TLS2_k127_6102888_9 Beta-lactamase superfamily domain K03476 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002134 246.0
TLS2_k127_6114018_0 alpha beta - - - 7.335e-238 757.0
TLS2_k127_6114018_1 Vault protein inter-alpha-trypsin domain K07114 - - 2.623e-209 679.0
TLS2_k127_6114018_10 PFAM Lytic transglycosylase catalytic - - - 0.0000000000000000000000000000000000000000000000005958 185.0
TLS2_k127_6114018_11 Sulfatase - - - 0.000000000000000000000000000001148 131.0
TLS2_k127_6114018_12 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000002621 128.0
TLS2_k127_6114018_13 Cupin domain - - - 0.00000000000000000000001853 112.0
TLS2_k127_6114018_14 Carboxypeptidase regulatory-like domain - - - 0.00000000000000003939 90.0
TLS2_k127_6114018_15 YCII-related domain - - - 0.0000000000000001084 94.0
TLS2_k127_6114018_16 NYN domain - - - 0.0002314 52.0
TLS2_k127_6114018_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 638.0
TLS2_k127_6114018_3 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 481.0
TLS2_k127_6114018_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 466.0
TLS2_k127_6114018_5 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 468.0
TLS2_k127_6114018_6 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 394.0
TLS2_k127_6114018_7 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 369.0
TLS2_k127_6114018_8 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 351.0
TLS2_k127_6114018_9 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000006604 229.0
TLS2_k127_6124085_0 Cytochrome c, class I - - - 5.63e-279 884.0
TLS2_k127_6124085_1 CHAT domain - - - 1.821e-253 816.0
TLS2_k127_6124085_11 Helix-turn-helix domain - - - 0.000005069 52.0
TLS2_k127_6124085_12 Phage derived protein Gp49-like (DUF891) - - - 0.00000511 51.0
TLS2_k127_6124085_2 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 536.0
TLS2_k127_6124085_3 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K01342,K08651,K14645,K14743,K20486,K20754 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009405,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0031224,GO:0031226,GO:0032879,GO:0040007,GO:0043170,GO:0044238,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0051046,GO:0051049,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.21.111,3.4.21.62,3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 406.0
TLS2_k127_6124085_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 299.0
TLS2_k127_6124085_5 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000512 290.0
TLS2_k127_6124085_6 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001503 284.0
TLS2_k127_6124085_7 NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003237 271.0
TLS2_k127_6124085_8 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000001103 197.0
TLS2_k127_6124085_9 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000337 144.0
TLS2_k127_6124468_0 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 301.0
TLS2_k127_6124468_1 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001114 256.0
TLS2_k127_6124468_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000004346 129.0
TLS2_k127_6139841_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 443.0
TLS2_k127_6139841_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 399.0
TLS2_k127_6139841_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004592 275.0
TLS2_k127_6139841_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000001066 211.0
TLS2_k127_6139841_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000003421 150.0
TLS2_k127_6139841_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000003569 153.0
TLS2_k127_6139841_6 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000001807 134.0
TLS2_k127_6142846_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 537.0
TLS2_k127_6142846_1 enterobactin catabolic process K07214,K09689 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 511.0
TLS2_k127_6142846_10 PFAM PemK-like protein K07171 - - 0.000000000000000001163 89.0
TLS2_k127_6142846_11 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000005025 81.0
TLS2_k127_6142846_12 Domain of unknown function (DUF4338) - - - 0.00001425 47.0
TLS2_k127_6142846_13 - - - - 0.0002392 47.0
TLS2_k127_6142846_2 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 512.0
TLS2_k127_6142846_3 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 422.0
TLS2_k127_6142846_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 392.0
TLS2_k127_6142846_5 protein flavinylation K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 295.0
TLS2_k127_6142846_6 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.00000000000000000000000000216 117.0
TLS2_k127_6142846_7 - - - - 0.0000000000000000000006727 109.0
TLS2_k127_6142846_8 - - - - 0.000000000000000000005246 106.0
TLS2_k127_6142846_9 transcriptional regulator K07726 - - 0.0000000000000000002014 91.0
TLS2_k127_6152526_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 0.0 1282.0
TLS2_k127_6152526_1 PFAM Glycosyl transferase family 2 - - - 1.501e-237 744.0
TLS2_k127_6152526_10 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000000002128 93.0
TLS2_k127_6152526_2 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 355.0
TLS2_k127_6152526_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 353.0
TLS2_k127_6152526_4 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000718 323.0
TLS2_k127_6152526_5 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 309.0
TLS2_k127_6152526_6 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001108 249.0
TLS2_k127_6152526_7 - - - - 0.0000000000000000000000000000000000000000000009223 169.0
TLS2_k127_6152526_8 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000005533 144.0
TLS2_k127_6152526_9 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000002387 102.0
TLS2_k127_6161033_0 Carboxypeptidase regulatory-like domain - - - 0.0 1358.0
TLS2_k127_6161033_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 530.0
TLS2_k127_6161033_10 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000261 205.0
TLS2_k127_6161033_11 - - - - 0.00000000000000000000000000000000000000000000000001709 190.0
TLS2_k127_6161033_12 Aldo Keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000005798 200.0
TLS2_k127_6161033_13 Chitin-binding domain type 3 - - - 0.000000000000000000000000000000000000001239 156.0
TLS2_k127_6161033_15 Ankyrin repeats (many copies) K21440 - - 0.0000000000000000006857 95.0
TLS2_k127_6161033_16 Involved in the tonB-independent uptake of proteins - - - 0.000000000000247 82.0
TLS2_k127_6161033_17 Periplasmic copper-binding protein (NosD) - - - 0.000000004318 69.0
TLS2_k127_6161033_18 PQQ-like domain - - - 0.0000002164 56.0
TLS2_k127_6161033_19 alginic acid biosynthetic process - - - 0.000002938 60.0
TLS2_k127_6161033_2 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 404.0
TLS2_k127_6161033_3 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 360.0
TLS2_k127_6161033_4 cellular response to dsDNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 339.0
TLS2_k127_6161033_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 321.0
TLS2_k127_6161033_6 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001296 269.0
TLS2_k127_6161033_7 Belongs to the TPP enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000005873 239.0
TLS2_k127_6161033_8 Belongs to the TPP enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000003068 229.0
TLS2_k127_6161033_9 response regulator K02485,K03413,K07684 - - 0.000000000000000000000000000000000000000000000000000000002842 211.0
TLS2_k127_6174165_0 Sodium:solute symporter family - - - 2.574e-263 822.0
TLS2_k127_6174165_1 ABC transporter K15738 - - 4.383e-205 654.0
TLS2_k127_6174165_10 Haloacid dehalogenase-like hydrolase K11777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006993 248.0
TLS2_k127_6174165_11 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000008338 193.0
TLS2_k127_6174165_12 lyase activity - - - 0.000000000000000000000000000000000000000000002792 177.0
TLS2_k127_6174165_13 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000001472 144.0
TLS2_k127_6174165_14 TIGRFAM diguanylate cyclase - - - 0.00000000000000000000000000000000002158 156.0
TLS2_k127_6174165_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 510.0
TLS2_k127_6174165_3 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 471.0
TLS2_k127_6174165_4 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 437.0
TLS2_k127_6174165_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 410.0
TLS2_k127_6174165_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 396.0
TLS2_k127_6174165_7 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 324.0
TLS2_k127_6174165_8 Beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 303.0
TLS2_k127_6174165_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001015 265.0
TLS2_k127_6207532_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 489.0
TLS2_k127_6207532_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000001346 240.0
TLS2_k127_6207532_2 PIN domain K07063 - - 0.00000000000000000000000000000000005256 138.0
TLS2_k127_6207532_3 Domain of unknown function (DUF4160) - - - 0.00000000000000000007866 91.0
TLS2_k127_6207532_4 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000006146 85.0
TLS2_k127_6211421_0 protocatechuate 3,4-dioxygenase activity - - - 0.0 1322.0
TLS2_k127_6211421_1 PFAM glycoside hydrolase family 29 K01206 - 3.2.1.51 7.64e-205 648.0
TLS2_k127_6211421_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 304.0
TLS2_k127_6211421_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001292 268.0
TLS2_k127_6211421_4 Belongs to the TPP enzyme family K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000004157 248.0
TLS2_k127_6212851_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 592.0
TLS2_k127_6212851_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 521.0
TLS2_k127_6212851_2 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 347.0
TLS2_k127_6212851_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 355.0
TLS2_k127_6212851_4 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001836 288.0
TLS2_k127_6212851_5 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000001819 221.0
TLS2_k127_6212851_6 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000002556 179.0
TLS2_k127_6212851_7 NmrA-like family - - - 0.00000000000000000000000002036 121.0
TLS2_k127_6213194_0 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 385.0
TLS2_k127_6213194_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 308.0
TLS2_k127_6225359_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 625.0
TLS2_k127_6225359_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 572.0
TLS2_k127_6225359_2 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000004112 190.0
TLS2_k127_6225359_3 methyltransferase activity - - - 0.0000000000000000000000006249 118.0
TLS2_k127_6225359_4 Cation transport regulator - - - 0.0000000000000000001597 99.0
TLS2_k127_6225359_5 - - - - 0.00000000000001022 83.0
TLS2_k127_6233411_0 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 492.0
TLS2_k127_6233411_1 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 472.0
TLS2_k127_6233411_2 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 394.0
TLS2_k127_6233411_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 363.0
TLS2_k127_6233411_4 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000003012 233.0
TLS2_k127_6233411_5 High-affinity nickel-transport protein - - - 0.00000000000000000000000000000000000000000000008103 178.0
TLS2_k127_6233411_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000002444 151.0
TLS2_k127_6233411_7 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000000001348 137.0
TLS2_k127_6233411_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000001199 143.0
TLS2_k127_6269327_0 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 2.158e-242 778.0
TLS2_k127_6269327_1 PFAM ABC transporter related K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000006149 165.0
TLS2_k127_6269327_2 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000001234 149.0
TLS2_k127_628508_0 Nicotinate phosphoribosyltransferase (NAPRTase) family K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 528.0
TLS2_k127_628508_1 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 476.0
TLS2_k127_628508_10 - - - - 0.000001277 57.0
TLS2_k127_628508_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 396.0
TLS2_k127_628508_3 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 398.0
TLS2_k127_628508_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 392.0
TLS2_k127_628508_5 carboxylic acid catabolic process K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 340.0
TLS2_k127_628508_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 331.0
TLS2_k127_628508_7 domain, Protein K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 319.0
TLS2_k127_628508_8 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000008549 206.0
TLS2_k127_628508_9 zinc ion binding K06204 - - 0.000000000000000000000000004414 114.0
TLS2_k127_6306392_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1182.0
TLS2_k127_6306392_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 6.404e-269 844.0
TLS2_k127_6306392_10 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000006725 193.0
TLS2_k127_6306392_11 G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000006343 199.0
TLS2_k127_6306392_12 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.00000000000000000000000000000000000000000000000008302 183.0
TLS2_k127_6306392_13 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.000000000000000000000000000000000000000000000002589 182.0
TLS2_k127_6306392_14 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000006611 182.0
TLS2_k127_6306392_15 Protein of unknown function (DUF1109) - - - 0.000000000000000002378 95.0
TLS2_k127_6306392_16 PFAM Response regulator receiver domain - - - 0.00000000000004102 76.0
TLS2_k127_6306392_17 - - - - 0.000000007545 59.0
TLS2_k127_6306392_2 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 589.0
TLS2_k127_6306392_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 572.0
TLS2_k127_6306392_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 400.0
TLS2_k127_6306392_5 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 321.0
TLS2_k127_6306392_6 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 322.0
TLS2_k127_6306392_7 2 iron, 2 sulfur cluster binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000005111 258.0
TLS2_k127_6306392_8 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000001914 216.0
TLS2_k127_6306392_9 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000005292 207.0
TLS2_k127_6310070_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002496 232.0
TLS2_k127_6310070_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000002545 147.0
TLS2_k127_6310070_2 Auxin Efflux Carrier K07088 - - 0.0003627 47.0
TLS2_k127_6339799_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000009623 160.0
TLS2_k127_6339799_1 cAMP biosynthetic process - - - 0.0000000000000000000004219 111.0
TLS2_k127_6339799_2 peptidyl-tyrosine sulfation - - - 0.00000000002229 76.0
TLS2_k127_6341600_0 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 439.0
TLS2_k127_6341600_1 PFAM TonB-dependent Receptor K16091 - - 0.0000000000000000000000000000001265 130.0
TLS2_k127_6351579_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 8.007e-253 792.0
TLS2_k127_6351579_1 PFAM Diacylglycerol kinase, catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001114 254.0
TLS2_k127_6351579_2 membrane-bound metal-dependent hydrolase K07038 - - 0.00000000000000000000000000000000003884 143.0
TLS2_k127_6351579_3 Anion-transporting ATPase - - - 0.000000000000000000001587 96.0
TLS2_k127_6356273_0 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000002038 131.0
TLS2_k127_6356273_1 - - - - 0.00000000000000000000000001197 120.0
TLS2_k127_6365529_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002059 274.0
TLS2_k127_6365529_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001022 236.0
TLS2_k127_6365529_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000001078 199.0
TLS2_k127_6365529_3 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000003705 60.0
TLS2_k127_6365529_4 Transcriptional regulatory protein, C terminal - - - 0.000009139 55.0
TLS2_k127_6365529_5 methyltransferase activity K20444 - - 0.0001409 46.0
TLS2_k127_6368321_0 Carboxypeptidase regulatory-like domain - - - 0.0 1095.0
TLS2_k127_6368321_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.17e-212 665.0
TLS2_k127_6368321_2 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 580.0
TLS2_k127_6368321_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 441.0
TLS2_k127_6368321_4 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 416.0
TLS2_k127_6368321_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 316.0
TLS2_k127_6368321_6 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000009869 190.0
TLS2_k127_6368321_7 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.0000000000000000000000000000000002059 135.0
TLS2_k127_6368321_8 - - - - 0.00000000152 69.0
TLS2_k127_6394430_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000004406 229.0
TLS2_k127_6394430_1 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000003554 178.0
TLS2_k127_6394430_2 multi-organism process K03195 - - 0.00000009578 55.0
TLS2_k127_6398185_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 550.0
TLS2_k127_6398185_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 330.0
TLS2_k127_6398185_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 299.0
TLS2_k127_6398185_3 Cytidylyltransferase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000875 252.0
TLS2_k127_6398185_4 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000000000000004514 230.0
TLS2_k127_6398185_5 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.000000000000000000009395 98.0
TLS2_k127_6398185_6 PFAM Integrase catalytic - - - 0.000000002038 59.0
TLS2_k127_6409402_0 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 2.156e-306 952.0
TLS2_k127_6409402_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 4.932e-252 790.0
TLS2_k127_6409402_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000004637 174.0
TLS2_k127_6409402_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000004698 151.0
TLS2_k127_6409402_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.158e-209 664.0
TLS2_k127_6409402_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 600.0
TLS2_k127_6409402_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 512.0
TLS2_k127_6409402_5 Peptidase C39 family K12541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 508.0
TLS2_k127_6409402_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 479.0
TLS2_k127_6409402_7 COG0845 membrane-fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 439.0
TLS2_k127_6409402_8 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000983 376.0
TLS2_k127_6409402_9 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000006148 202.0
TLS2_k127_6449704_0 Cytochrome c - - - 2.57e-272 878.0
TLS2_k127_6449704_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 353.0
TLS2_k127_6449704_2 - - - - 0.000000000000000000001381 100.0
TLS2_k127_6449704_3 Phage shock protein C, PspC K03973 - - 0.0000000000000000000208 94.0
TLS2_k127_6462309_0 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005449 284.0
TLS2_k127_6462309_2 DNA polymerase beta domain protein region K07075 - - 0.0000000000000000000000000003248 117.0
TLS2_k127_6476684_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000005514 222.0
TLS2_k127_6476684_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000002885 209.0
TLS2_k127_6476684_2 - - - - 0.000000000000000000000003548 104.0
TLS2_k127_6496470_0 amine dehydrogenase activity - - - 4.73e-292 927.0
TLS2_k127_6496470_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000001637 68.0
TLS2_k127_6498625_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 417.0
TLS2_k127_6501822_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1506.0
TLS2_k127_6501822_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.834e-214 685.0
TLS2_k127_6501822_10 - - - - 0.000000000009469 71.0
TLS2_k127_6501822_11 Mechanosensitive ion channel K16053 - - 0.00000000003684 66.0
TLS2_k127_6501822_12 - - - - 0.00000006672 63.0
TLS2_k127_6501822_13 tetratricopeptide repeat - - - 0.00001989 57.0
TLS2_k127_6501822_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 634.0
TLS2_k127_6501822_3 sulfite oxidase - - - 0.00000000000000000000000000000000000000000000000000002572 201.0
TLS2_k127_6501822_4 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000009825 186.0
TLS2_k127_6501822_5 - - - - 0.0000000000000000000000000000000000000000007663 165.0
TLS2_k127_6501822_7 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.000000000000000000000000000000000006644 143.0
TLS2_k127_6501822_8 Large extracellular alpha-helical protein K12287 - - 0.0000000000000000000000000003436 133.0
TLS2_k127_6501822_9 - - - - 0.000000000000000000006076 98.0
TLS2_k127_6511813_0 Carboxypeptidase regulatory-like domain - - - 0.0 1360.0
TLS2_k127_6511813_1 acetylesterase activity - - - 7.46e-210 671.0
TLS2_k127_6511813_2 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 591.0
TLS2_k127_6511813_3 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 327.0
TLS2_k127_6511813_4 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001339 283.0
TLS2_k127_6511813_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000009099 211.0
TLS2_k127_6511813_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000003092 148.0
TLS2_k127_6511813_8 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000003405 71.0
TLS2_k127_6511813_9 cytochrome complex assembly K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.0000000004128 67.0
TLS2_k127_6529455_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0 1040.0
TLS2_k127_6529455_1 type VI secretion protein K11900 - - 1.803e-267 828.0
TLS2_k127_6529455_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000002498 224.0
TLS2_k127_6529455_11 anti-sigma factor antagonist activity K11897 - - 0.0000000000000000000000000000000000000000000136 169.0
TLS2_k127_6529455_12 histone H2A K63-linked ubiquitination K11894 - - 0.00000000000000000000000000000000000000002514 158.0
TLS2_k127_6529455_13 ribonuclease activity - - - 0.00000000000000000000000002156 113.0
TLS2_k127_6529455_14 Type VI secretion system effector, Hcp K06887,K11903 - - 0.000000000000000000002191 100.0
TLS2_k127_6529455_15 Type VI secretion system effector, Hcp K06887,K11903 - - 0.000000000000000000005536 98.0
TLS2_k127_6529455_16 - - - - 0.000000000358 70.0
TLS2_k127_6529455_17 - - - - 0.0000161 53.0
TLS2_k127_6529455_18 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00002775 53.0
TLS2_k127_6529455_2 Type VI secretion system, TssF K11895,K11896 - - 2.845e-241 759.0
TLS2_k127_6529455_3 TIGRFAM type VI secretion system Vgr family protein K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 591.0
TLS2_k127_6529455_4 ImpA, N-terminal, type VI secretion system K11902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 504.0
TLS2_k127_6529455_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 400.0
TLS2_k127_6529455_6 Type VI secretion, TssG K11895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 328.0
TLS2_k127_6529455_7 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 320.0
TLS2_k127_6529455_8 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 304.0
TLS2_k127_6529455_9 PFAM Uncharacterised conserved protein UCP028301 K11901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009647 259.0
TLS2_k127_6549562_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004897 279.0
TLS2_k127_6549562_1 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000001985 194.0
TLS2_k127_6550138_0 Domain of unknown function (DUF1998) K06877 - - 0.0 1142.0
TLS2_k127_6550138_1 PFAM Xylose isomerase K01820 - 5.3.1.14 3.413e-201 633.0
TLS2_k127_6550138_10 TIGRFAM death-on-curing family protein K07341 - - 0.0000000000000000000000000000000000004065 143.0
TLS2_k127_6550138_12 - - - - 0.0002477 48.0
TLS2_k127_6550138_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 3.585e-195 620.0
TLS2_k127_6550138_3 protein kinase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 571.0
TLS2_k127_6550138_4 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 373.0
TLS2_k127_6550138_5 BNR repeat-like domain K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 349.0
TLS2_k127_6550138_6 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 329.0
TLS2_k127_6550138_7 FdhD/NarQ family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 291.0
TLS2_k127_6550138_8 Domain of unknown function (DUF4123) - - - 0.00000000000000000000000000000000000000003734 158.0
TLS2_k127_6550138_9 RNA recognition motif - - - 0.000000000000000000000000000000000000002628 151.0
TLS2_k127_65743_0 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 287.0
TLS2_k127_65743_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.000000000000000000000000000001074 125.0
TLS2_k127_65743_2 Rv0623-like transcription factor K19687 - - 0.00000000000000001879 85.0
TLS2_k127_6579206_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1249.0
TLS2_k127_6579206_1 Carboxypeptidase regulatory-like domain - - - 0.0 1092.0
TLS2_k127_6579206_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.267e-318 1000.0
TLS2_k127_6579206_3 Acetyl xylan esterase (AXE1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 427.0
TLS2_k127_6579206_4 Creatininase K01470 - 3.5.2.10 0.0000008969 51.0
TLS2_k127_6581277_0 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 449.0
TLS2_k127_6581277_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000005969 114.0
TLS2_k127_6610429_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 555.0
TLS2_k127_6610429_1 - - - - 0.00000000000000000000000001676 114.0
TLS2_k127_6611777_0 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 8.774e-249 789.0
TLS2_k127_6611777_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 596.0
TLS2_k127_6611777_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 458.0
TLS2_k127_6611777_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 381.0
TLS2_k127_6611777_4 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 368.0
TLS2_k127_6611777_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 287.0
TLS2_k127_6611777_7 GDSL-like Lipase/Acylhydrolase K21026 - 3.1.1.80 0.0000000006695 65.0
TLS2_k127_6637602_0 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 372.0
TLS2_k127_6637602_1 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000003423 229.0
TLS2_k127_6637602_2 - - - - 0.00000000000000000000000000000000000000000000000000002027 205.0
TLS2_k127_6637602_3 - - - - 0.00000000000000000000000000000000000000000000000007999 203.0
TLS2_k127_6637602_4 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000000000000000000000000000000000000001648 177.0
TLS2_k127_6637602_6 Protein of unknown function (DUF2393) - - - 0.0000000000000000000000000000000001562 140.0
TLS2_k127_6637602_7 - - - - 0.000000000000000000000008925 111.0
TLS2_k127_6640537_0 Cupin domain - - - 0.0000000000000000000000000000000000000000000000007189 184.0
TLS2_k127_6640537_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000002252 139.0
TLS2_k127_6645005_0 transport - - - 8.472e-315 1000.0
TLS2_k127_6645005_1 Zinc carboxypeptidase - - - 1.083e-312 981.0
TLS2_k127_6645005_10 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 528.0
TLS2_k127_6645005_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 521.0
TLS2_k127_6645005_12 phosphoglucosamine mutase activity K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 505.0
TLS2_k127_6645005_13 BNR repeat-like domain K05989 - 3.2.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 511.0
TLS2_k127_6645005_14 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 478.0
TLS2_k127_6645005_15 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 430.0
TLS2_k127_6645005_16 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 406.0
TLS2_k127_6645005_17 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 406.0
TLS2_k127_6645005_18 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 406.0
TLS2_k127_6645005_19 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 382.0
TLS2_k127_6645005_2 Ribosomal protein S1 K02945 - - 1.699e-236 744.0
TLS2_k127_6645005_20 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 387.0
TLS2_k127_6645005_21 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 369.0
TLS2_k127_6645005_22 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 356.0
TLS2_k127_6645005_23 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 308.0
TLS2_k127_6645005_24 Alpha beta hydrolase fold-3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 301.0
TLS2_k127_6645005_25 Dimerisation domain K09846 - 2.1.1.210 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001103 287.0
TLS2_k127_6645005_26 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002635 270.0
TLS2_k127_6645005_27 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003244 271.0
TLS2_k127_6645005_28 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 254.0
TLS2_k127_6645005_29 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005752 258.0
TLS2_k127_6645005_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 3.337e-235 739.0
TLS2_k127_6645005_30 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000002689 243.0
TLS2_k127_6645005_31 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005101 252.0
TLS2_k127_6645005_32 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000001309 227.0
TLS2_k127_6645005_33 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
TLS2_k127_6645005_34 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000004771 224.0
TLS2_k127_6645005_35 ATP-dependent protease La (LON) substrate-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000376 215.0
TLS2_k127_6645005_36 - - - - 0.0000000000000000000000000000000000000000000000000000000000221 212.0
TLS2_k127_6645005_37 transmembrane transporter activity K03535,K08194 - - 0.000000000000000000000000000000000000000000000000000000001396 207.0
TLS2_k127_6645005_38 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000000000000000000000000000000000000000000008093 209.0
TLS2_k127_6645005_39 - - - - 0.000000000000000000000000000000000000000000001595 174.0
TLS2_k127_6645005_4 His Kinase A (phosphoacceptor) domain - - - 3.408e-233 738.0
TLS2_k127_6645005_40 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000123 158.0
TLS2_k127_6645005_41 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000000001877 158.0
TLS2_k127_6645005_42 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00000000000000000000000000000000000000000206 158.0
TLS2_k127_6645005_43 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000002369 164.0
TLS2_k127_6645005_44 DoxX K15977 - - 0.0000000000000000000000000000000000000003019 154.0
TLS2_k127_6645005_45 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000000002779 154.0
TLS2_k127_6645005_46 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000003811 139.0
TLS2_k127_6645005_47 Helix-turn-helix domain - - - 0.0000000000000000000000000000000006207 136.0
TLS2_k127_6645005_48 PIN domain - - - 0.000000000000000000000000000000004502 135.0
TLS2_k127_6645005_49 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000004849 121.0
TLS2_k127_6645005_5 carboxylic acid catabolic process K18334 - 4.2.1.68 1.63e-213 669.0
TLS2_k127_6645005_50 - - - - 0.000000000000000000000000000189 117.0
TLS2_k127_6645005_51 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000001602 108.0
TLS2_k127_6645005_52 - - - - 0.00000000000000000000005177 102.0
TLS2_k127_6645005_53 Beta-lactamase superfamily domain - - - 0.0000000000000000000001066 105.0
TLS2_k127_6645005_54 JAB/MPN domain - - - 0.0000000000000000009492 91.0
TLS2_k127_6645005_55 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000002626 79.0
TLS2_k127_6645005_56 Ribonuclease P K03536 - 3.1.26.5 0.00000009377 59.0
TLS2_k127_6645005_57 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000001824 58.0
TLS2_k127_6645005_59 Transcriptional regulator - - - 0.0004005 46.0
TLS2_k127_6645005_6 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.23e-204 645.0
TLS2_k127_6645005_7 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 2.141e-196 622.0
TLS2_k127_6645005_8 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 582.0
TLS2_k127_6645005_9 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 544.0
TLS2_k127_6646209_0 Carboxypeptidase regulatory-like domain - - - 1.749e-261 842.0
TLS2_k127_6646209_1 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 562.0
TLS2_k127_6646209_10 Pfam:DUF2276 - - - 0.0000000000000000004286 93.0
TLS2_k127_6646209_11 cAMP biosynthetic process - - - 0.0000000000003074 74.0
TLS2_k127_6646209_12 protocatechuate 3,4-dioxygenase activity K00449 - 1.13.11.3 0.000000004944 69.0
TLS2_k127_6646209_13 Protein kinase domain K12132 - 2.7.11.1 0.0001022 49.0
TLS2_k127_6646209_14 Nuclear transport factor 2 (NTF2) domain K17265 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006807,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010494,GO:0016236,GO:0016579,GO:0019538,GO:0032386,GO:0032879,GO:0032991,GO:0034517,GO:0035770,GO:0035973,GO:0036211,GO:0036464,GO:0043021,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0051049,GO:0060341,GO:0060627,GO:0060628,GO:0061912,GO:0061919,GO:0065007,GO:0070646,GO:0070647,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1905538,GO:1990861,GO:1990904 3.6.4.12,3.6.4.13 0.0006968 44.0
TLS2_k127_6646209_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 412.0
TLS2_k127_6646209_3 Plasmid encoded RepA protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 334.0
TLS2_k127_6646209_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 326.0
TLS2_k127_6646209_5 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001291 235.0
TLS2_k127_6646209_6 Type IV leader peptidase family K02278 - 3.4.23.43 0.0000000000000000000000000000000000000000000000007828 180.0
TLS2_k127_6646209_7 TIR domain - - - 0.0000000000000000000000000000000000000000002546 179.0
TLS2_k127_6646209_8 Transcriptional regulator, AbiEi antitoxin, Type IV TA system - - - 0.000000000000000000000000000000000000005061 149.0
TLS2_k127_6652845_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 573.0
TLS2_k127_6652845_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009665 276.0
TLS2_k127_6652845_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01639,K01714 - 4.1.3.3,4.3.3.7 0.000000000000000000000000000000000000000008892 159.0
TLS2_k127_6652845_3 Domain of unknown function (DUF3368) K07066 - - 0.00000000000000000000000000000000000001437 150.0
TLS2_k127_6652845_4 nuclease activity - - - 0.00000000000000000000000000000000005507 139.0
TLS2_k127_6652845_5 PFAM Uncharacterised protein family UPF0175 - - - 0.00000000000000000000000308 104.0
TLS2_k127_6652845_6 PQQ-like domain - - - 0.00000000000000001139 85.0
TLS2_k127_6652845_7 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000205 84.0
TLS2_k127_6652845_9 - - - - 0.0001765 46.0
TLS2_k127_6657765_0 4Fe-4S dicluster domain K00184 - - 3.777e-267 846.0
TLS2_k127_6657765_1 PFAM Polysulphide reductase, NrfD - - - 3.479e-213 669.0
TLS2_k127_6660582_0 AcrB/AcrD/AcrF family - - - 0.0 1422.0
TLS2_k127_6660582_1 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1157.0
TLS2_k127_6660582_10 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001104 259.0
TLS2_k127_6660582_11 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001771 243.0
TLS2_k127_6660582_12 RNA recognition motif - - - 0.00000000000000000000000000000002469 128.0
TLS2_k127_6660582_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 4.062e-196 619.0
TLS2_k127_6660582_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 636.0
TLS2_k127_6660582_4 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 465.0
TLS2_k127_6660582_5 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 457.0
TLS2_k127_6660582_6 PhoD-like phosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 458.0
TLS2_k127_6660582_7 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 400.0
TLS2_k127_6660582_8 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 384.0
TLS2_k127_6660582_9 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009635 282.0
TLS2_k127_6672152_0 COG1012 NAD-dependent aldehyde - - - 1.912e-213 671.0
TLS2_k127_6672152_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 572.0
TLS2_k127_6672152_2 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 340.0
TLS2_k127_6672152_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000007028 208.0
TLS2_k127_6672152_4 - - - - 0.0006089 44.0
TLS2_k127_6687527_0 Belongs to the UPF0753 family K09822 - - 0.0 1056.0
TLS2_k127_6687527_1 TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 564.0
TLS2_k127_6687527_2 aldo keto reductase K17744 - 1.1.1.316 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 369.0
TLS2_k127_6687527_3 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 360.0
TLS2_k127_6687527_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 349.0
TLS2_k127_6687527_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 341.0
TLS2_k127_6687527_6 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 345.0
TLS2_k127_6687527_7 - K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001214 261.0
TLS2_k127_6687527_8 Likely ribonuclease with RNase H fold. K07447 - - 0.0000000000000000000000000000000000000008819 153.0
TLS2_k127_6687699_0 phosphorelay sensor kinase activity K02484,K07638,K07639,K07640,K07650 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 410.0
TLS2_k127_6687699_1 PFAM response regulator receiver K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 307.0
TLS2_k127_6687699_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 305.0
TLS2_k127_6687699_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003101 291.0
TLS2_k127_6687699_4 DNA mediated transformation K04096 - - 0.000000000000000000000000000000000000000000085 166.0
TLS2_k127_6726191_0 Arylsulfatase a K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 498.0
TLS2_k127_6726191_10 peptidyl-tyrosine sulfation - - - 0.000000000000000003832 90.0
TLS2_k127_6726191_11 TIR domain - - - 0.0000000000000001153 93.0
TLS2_k127_6726191_12 Putative restriction endonuclease - - - 0.000000000000001957 81.0
TLS2_k127_6726191_13 efflux transmembrane transporter activity K02004 - - 0.00000000000001726 75.0
TLS2_k127_6726191_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 332.0
TLS2_k127_6726191_4 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009582 273.0
TLS2_k127_6726191_5 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006756 259.0
TLS2_k127_6726191_6 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000001175 209.0
TLS2_k127_6726191_7 DinB family - - - 0.000000000000000000000000000000000001679 144.0
TLS2_k127_6726191_8 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000002295 135.0
TLS2_k127_6726191_9 - - - - 0.000000000000000000000002235 113.0
TLS2_k127_6728351_0 MacB-like periplasmic core domain - - - 5.381e-227 727.0
TLS2_k127_6728351_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 485.0
TLS2_k127_6731741_0 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 395.0
TLS2_k127_6731741_1 phosphatidate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000003757 201.0
TLS2_k127_674880_0 - - - - 7.886e-207 661.0
TLS2_k127_674880_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 421.0
TLS2_k127_674880_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000001426 138.0
TLS2_k127_6749333_0 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 419.0
TLS2_k127_6749333_1 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 357.0
TLS2_k127_6749333_2 WD40 domain protein beta Propeller - - - 0.0000000000000000000000000000000000000000000000000001521 195.0
TLS2_k127_6752392_0 Cytochrome c554 and c-prime - - - 0.0 1122.0
TLS2_k127_6752392_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0 1103.0
TLS2_k127_6752392_10 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005534 285.0
TLS2_k127_6752392_11 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000003101 235.0
TLS2_k127_6752392_12 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000005053 179.0
TLS2_k127_6752392_13 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000000000000000000000001365 179.0
TLS2_k127_6752392_14 BON domain - - - 0.000000000000000000000000000000000000000000000471 172.0
TLS2_k127_6752392_15 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000007293 169.0
TLS2_k127_6752392_16 PQQ-like domain - - - 0.0000000000000000000000000000000000000001485 157.0
TLS2_k127_6752392_18 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000000001977 149.0
TLS2_k127_6752392_19 Protein of unknown function (DUF433) - - - 0.0000000000000000000002297 99.0
TLS2_k127_6752392_2 ASPIC and UnbV - - - 5.926e-258 805.0
TLS2_k127_6752392_20 - - - - 0.000000000000000000001891 107.0
TLS2_k127_6752392_22 PEP-CTERM system TPR-repeat lipoprotein - - - 0.000000000000009828 87.0
TLS2_k127_6752392_23 - - - - 0.000000004617 62.0
TLS2_k127_6752392_3 Peptidase, family M49 - - - 3.385e-227 718.0
TLS2_k127_6752392_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 9.183e-205 646.0
TLS2_k127_6752392_5 FtsX-like permease family - - - 1.918e-198 659.0
TLS2_k127_6752392_6 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 610.0
TLS2_k127_6752392_7 cystathionine gamma-synthase activity K01739,K01740,K01760,K01761,K10764 - 2.5.1.48,2.5.1.49,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 531.0
TLS2_k127_6752392_8 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 527.0
TLS2_k127_6752392_9 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 381.0
TLS2_k127_675368_0 transport - - - 0.0 1197.0
TLS2_k127_675368_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 555.0
TLS2_k127_675368_10 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000000000001198 140.0
TLS2_k127_675368_11 - - - - 0.00000000000000000000000000004034 128.0
TLS2_k127_675368_12 DinB family - - - 0.0000000000000000000001826 103.0
TLS2_k127_675368_13 Protein of unknown function (DUF433) - - - 0.00000000000000001606 87.0
TLS2_k127_675368_14 - - - - 0.00000000000003199 79.0
TLS2_k127_675368_15 Protein of unknown function (DUF433) - - - 0.000000000004832 71.0
TLS2_k127_675368_16 - - - - 0.000243 52.0
TLS2_k127_675368_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 568.0
TLS2_k127_675368_3 DEAD DEAH box helicase domain protein K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 489.0
TLS2_k127_675368_4 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 437.0
TLS2_k127_675368_5 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 355.0
TLS2_k127_675368_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 353.0
TLS2_k127_675368_7 sequence-specific DNA binding K01239,K02855,K07506,K18199 - 3.2.2.1,4.2.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 318.0
TLS2_k127_675368_8 Flavodoxin-like fold K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000001157 210.0
TLS2_k127_675368_9 DinB family - - - 0.0000000000000000000000000000000000000000007132 164.0
TLS2_k127_6754696_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 496.0
TLS2_k127_6754696_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 327.0
TLS2_k127_6754696_2 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005555 281.0
TLS2_k127_6754696_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002357 243.0
TLS2_k127_6754696_4 region 4 type 2 K03088 - - 0.00000000000000000000002946 110.0
TLS2_k127_6754696_5 - - - - 0.0000000000000000000009851 102.0
TLS2_k127_6754696_7 Anti-sigma factor - - - 0.000000004404 70.0
TLS2_k127_6754696_8 restriction endonuclease K07448 - - 0.00000002732 60.0
TLS2_k127_6763549_0 TIGRFAM ATP-dependent DNA helicase, RecQ family K03654 - 3.6.4.12 1.191e-215 702.0
TLS2_k127_6763549_1 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 386.0
TLS2_k127_677546_0 amine dehydrogenase activity - - - 3.238e-252 812.0
TLS2_k127_677546_1 AMP-binding enzyme C-terminal domain K00666 - - 4.789e-204 650.0
TLS2_k127_677546_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000003952 148.0
TLS2_k127_677546_11 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000001641 117.0
TLS2_k127_677546_12 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000004485 83.0
TLS2_k127_677546_13 Protein of unknown function (DUF465) - - - 0.00000004844 62.0
TLS2_k127_677546_2 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 564.0
TLS2_k127_677546_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 539.0
TLS2_k127_677546_4 Divalent cation transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 517.0
TLS2_k127_677546_5 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 394.0
TLS2_k127_677546_6 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 384.0
TLS2_k127_677546_7 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 352.0
TLS2_k127_677546_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000691 240.0
TLS2_k127_6780480_0 class II (D K K01893 - 6.1.1.22 1.002e-230 722.0
TLS2_k127_6780480_1 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 464.0
TLS2_k127_6780480_2 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 445.0
TLS2_k127_6780480_3 PFAM Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 351.0
TLS2_k127_6780480_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000000000000000000000000000000000001423 148.0
TLS2_k127_6780480_5 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000002506 117.0
TLS2_k127_6780480_6 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000002633 97.0
TLS2_k127_6780480_7 InterPro IPR014922 - - - 0.000000000000000000004832 93.0
TLS2_k127_6780480_8 class II (D K and N) K01893 - 6.1.1.22 0.0000000000002491 70.0
TLS2_k127_6781483_0 Planctomycete cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 386.0
TLS2_k127_6781483_1 Sulfatase-modifying factor enzyme 1 K13730 - - 0.00000000000000000000000003377 123.0
TLS2_k127_6793796_0 Protein of unknown function (DUF1552) - - - 0.000000000000000000001285 99.0
TLS2_k127_6793796_1 deoxyhypusine monooxygenase activity K03301 - - 0.0000000000000002759 92.0
TLS2_k127_6803263_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 516.0
TLS2_k127_6803263_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000001396 221.0
TLS2_k127_6803263_2 - - - - 0.00000000000000000000000000000000000000000000278 175.0
TLS2_k127_6803263_3 HDOD domain - - - 0.0000000000000000000000000000005864 129.0
TLS2_k127_6803263_4 PFAM Archaeal ATPase - - - 0.0000000000000000000000000005405 132.0
TLS2_k127_6803263_5 NAD dependent epimerase/dehydratase family - - - 0.0006911 42.0
TLS2_k127_6807429_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 475.0
TLS2_k127_6807429_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 480.0
TLS2_k127_681416_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K16843 - 1.1.1.310 0.0000000000000000000000000000000000000000000000000006811 188.0
TLS2_k127_6820806_0 CRISPR-associated helicase, Cas3 K07012 - - 4.938e-195 647.0
TLS2_k127_6820806_1 CRISPR-associated protein, GSU0054 family K19132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 339.0
TLS2_k127_6820806_2 crispr-associated protein K19131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 333.0
TLS2_k127_6820806_3 CRISPR associated protein Cas1 K15342 - - 0.00000000000000000000000000000000000000000000000000000000000000008357 226.0
TLS2_k127_6820806_4 - - - - 0.00000000000000000000000000000000000000000000000000008204 199.0
TLS2_k127_6820806_5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.0000000000000000000000000000000000000000000001992 168.0
TLS2_k127_6838512_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1077.0
TLS2_k127_6838512_1 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 1.09e-321 1029.0
TLS2_k127_6838512_10 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 2.635e-226 707.0
TLS2_k127_6838512_11 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 8.705e-222 713.0
TLS2_k127_6838512_12 Carboxypeptidase regulatory-like domain - - - 1.453e-203 673.0
TLS2_k127_6838512_13 efflux transmembrane transporter activity K02004 - - 1.582e-202 638.0
TLS2_k127_6838512_14 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 559.0
TLS2_k127_6838512_15 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 527.0
TLS2_k127_6838512_16 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 533.0
TLS2_k127_6838512_17 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 531.0
TLS2_k127_6838512_18 PFAM Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 518.0
TLS2_k127_6838512_19 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 497.0
TLS2_k127_6838512_2 Amidohydrolase family - - - 2.055e-315 1001.0
TLS2_k127_6838512_20 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 495.0
TLS2_k127_6838512_21 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 484.0
TLS2_k127_6838512_22 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 459.0
TLS2_k127_6838512_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 464.0
TLS2_k127_6838512_24 PFAM Peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 460.0
TLS2_k127_6838512_25 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 467.0
TLS2_k127_6838512_26 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 407.0
TLS2_k127_6838512_27 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009351 362.0
TLS2_k127_6838512_28 Peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 365.0
TLS2_k127_6838512_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 363.0
TLS2_k127_6838512_3 PFAM type III restriction protein res subunit - - - 1.65e-288 908.0
TLS2_k127_6838512_30 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 331.0
TLS2_k127_6838512_31 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 330.0
TLS2_k127_6838512_32 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 329.0
TLS2_k127_6838512_33 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 318.0
TLS2_k127_6838512_34 adenosylhomocysteine nucleosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 311.0
TLS2_k127_6838512_35 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 306.0
TLS2_k127_6838512_36 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 302.0
TLS2_k127_6838512_37 carboxylic acid catabolic process K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 298.0
TLS2_k127_6838512_38 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003597 286.0
TLS2_k127_6838512_39 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005075 285.0
TLS2_k127_6838512_4 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 6.079e-273 868.0
TLS2_k127_6838512_40 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000001477 249.0
TLS2_k127_6838512_41 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000004188 243.0
TLS2_k127_6838512_42 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000001776 218.0
TLS2_k127_6838512_43 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001853 216.0
TLS2_k127_6838512_44 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000004951 216.0
TLS2_k127_6838512_45 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000002199 222.0
TLS2_k127_6838512_46 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000001006 207.0
TLS2_k127_6838512_47 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000007135 198.0
TLS2_k127_6838512_48 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000003735 192.0
TLS2_k127_6838512_49 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000029 203.0
TLS2_k127_6838512_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 3.285e-263 826.0
TLS2_k127_6838512_50 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000001276 191.0
TLS2_k127_6838512_51 Leucine Rich repeat - - - 0.0000000000000000000000000000000000000000002506 180.0
TLS2_k127_6838512_52 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000008306 156.0
TLS2_k127_6838512_53 Translation initiation factor 1A / IF-1 K02518 - - 0.0000000000000000000000000000000001694 134.0
TLS2_k127_6838512_54 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.0000000000000000000000000000000004004 141.0
TLS2_k127_6838512_55 - - - - 0.0000000000000000000000000192 121.0
TLS2_k127_6838512_56 - - - - 0.000000000000000005648 94.0
TLS2_k127_6838512_58 - - - - 0.0000000005097 70.0
TLS2_k127_6838512_6 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 1.922e-260 822.0
TLS2_k127_6838512_60 PFAM Tetratricopeptide repeat - - - 0.00000004756 64.0
TLS2_k127_6838512_62 TPR repeat - - - 0.00000009399 65.0
TLS2_k127_6838512_63 and their inactivated homologs K03568 - - 0.000002126 54.0
TLS2_k127_6838512_7 transport - - - 2.694e-254 824.0
TLS2_k127_6838512_8 PFAM WD domain, G-beta repeat - - - 1.444e-241 794.0
TLS2_k127_6838512_9 gluconolactonase activity K14274,K20274 - - 1.234e-227 748.0
TLS2_k127_684674_0 TonB-dependent receptor - - - 1.347e-225 735.0
TLS2_k127_684674_1 carboxylic acid catabolic process K01684 - 4.2.1.6 1.472e-197 621.0
TLS2_k127_684674_10 Phage major capsid protein E - - - 0.0001393 52.0
TLS2_k127_684674_2 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 456.0
TLS2_k127_684674_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 420.0
TLS2_k127_684674_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 382.0
TLS2_k127_684674_5 Phage major capsid protein E - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 299.0
TLS2_k127_684674_6 ATPase involved in DNA repair K03546 - - 0.00000000000000000000000000000000000000000000000000000001372 224.0
TLS2_k127_684674_7 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000002122 156.0
TLS2_k127_684674_8 ParB-like nuclease domain - - - 0.0000000000000000000000000001161 124.0
TLS2_k127_684674_9 regulation of photosynthesis, light reaction K08994 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000002271 54.0
TLS2_k127_6851066_0 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0 1221.0
TLS2_k127_6851066_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1132.0
TLS2_k127_6851066_10 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001237 256.0
TLS2_k127_6851066_11 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008188 231.0
TLS2_k127_6851066_12 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001739 226.0
TLS2_k127_6851066_13 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000003087 186.0
TLS2_k127_6851066_14 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.00000000000000000000000000000000000003513 152.0
TLS2_k127_6851066_15 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000001977 117.0
TLS2_k127_6851066_16 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000002701 123.0
TLS2_k127_6851066_17 PFAM DUF218 domain - - - 0.00000000000000000001163 103.0
TLS2_k127_6851066_18 dehydrogenases and related proteins - - - 0.00000000000000000001301 96.0
TLS2_k127_6851066_19 transferase, hexapeptide repeat - - - 0.00000001864 63.0
TLS2_k127_6851066_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 7.217e-308 955.0
TLS2_k127_6851066_20 Transposase - - - 0.00001248 47.0
TLS2_k127_6851066_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 613.0
TLS2_k127_6851066_4 nitrite transmembrane transporter activity K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 595.0
TLS2_k127_6851066_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 382.0
TLS2_k127_6851066_6 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 344.0
TLS2_k127_6851066_7 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 347.0
TLS2_k127_6851066_8 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 321.0
TLS2_k127_6851066_9 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 284.0
TLS2_k127_6852129_0 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 592.0
TLS2_k127_6852129_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 570.0
TLS2_k127_6852129_10 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000007617 232.0
TLS2_k127_6852129_11 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000134 210.0
TLS2_k127_6852129_12 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000009362 206.0
TLS2_k127_6852129_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000001139 190.0
TLS2_k127_6852129_14 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000005352 175.0
TLS2_k127_6852129_15 - - - - 0.000000000000000000000000000000000000002225 154.0
TLS2_k127_6852129_16 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000001107 140.0
TLS2_k127_6852129_17 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000005701 143.0
TLS2_k127_6852129_18 Transcriptional regulator - - - 0.000000000000000000000000001304 132.0
TLS2_k127_6852129_19 acylphosphatase activity K01512 - 3.6.1.7 0.00000000000000000001258 99.0
TLS2_k127_6852129_2 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 472.0
TLS2_k127_6852129_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 440.0
TLS2_k127_6852129_4 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 435.0
TLS2_k127_6852129_5 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 388.0
TLS2_k127_6852129_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 354.0
TLS2_k127_6852129_8 PFAM Ribonuclease BN-like family K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001032 262.0
TLS2_k127_6852129_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000001857 246.0
TLS2_k127_6857662_0 Cytochrome c, class I - - - 2.196e-283 890.0
TLS2_k127_6857662_1 Putative esterase - - - 6.177e-245 773.0
TLS2_k127_6857662_10 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000007044 56.0
TLS2_k127_6857662_2 Protein of unknown function (DUF1501) - - - 1.297e-229 719.0
TLS2_k127_6857662_3 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 396.0
TLS2_k127_6857662_4 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002496 253.0
TLS2_k127_6857662_5 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003768 255.0
TLS2_k127_6857662_6 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000000000000000000006242 182.0
TLS2_k127_6857662_7 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000001559 131.0
TLS2_k127_6857662_8 addiction module antidote protein HigA K21498 - - 0.000000000000000000000000000005532 120.0
TLS2_k127_6857662_9 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000001497 106.0
TLS2_k127_6858014_0 Carboxypeptidase regulatory-like domain - - - 3.873e-286 913.0
TLS2_k127_6858014_1 transport - - - 1.065e-280 897.0
TLS2_k127_6858014_10 Mandelate racemase muconate lactonizing enzyme K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008093 312.0
TLS2_k127_6858014_11 Short-chain dehydrogenase reductase SDR K00059,K18337 - 1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378 0.0000000000000000000000000000000000000000000000000000000000000001003 232.0
TLS2_k127_6858014_12 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.0000000000000000000000000000000000000000000000000000000000002349 222.0
TLS2_k127_6858014_13 PFAM von Willebrand factor type A K07114,K12511 - - 0.000000000000000000000000000000000000000000000000000000000000729 221.0
TLS2_k127_6858014_14 - - - - 0.0000000000000000000000000000000000001046 152.0
TLS2_k127_6858014_15 gntR family - - - 0.0000000000000000000000000000000001314 143.0
TLS2_k127_6858014_16 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000006774 129.0
TLS2_k127_6858014_17 Tetratricopeptide repeat - - - 0.00001022 57.0
TLS2_k127_6858014_2 Cytochrome c, class I - - - 1.325e-275 871.0
TLS2_k127_6858014_3 transport - - - 1.513e-265 855.0
TLS2_k127_6858014_4 ASPIC and UnbV - - - 1.189e-215 694.0
TLS2_k127_6858014_5 Sigma-70 region 3 K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 444.0
TLS2_k127_6858014_6 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 397.0
TLS2_k127_6858014_7 arylformamidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 359.0
TLS2_k127_6858014_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 362.0
TLS2_k127_6858014_9 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 332.0
TLS2_k127_6859972_0 kinase activity K07154 - 2.7.11.1 6.295e-279 868.0
TLS2_k127_6859972_1 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 601.0
TLS2_k127_6859972_2 AAA-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 580.0
TLS2_k127_6859972_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 442.0
TLS2_k127_6859972_4 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001025 259.0
TLS2_k127_6859972_5 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000008921 224.0
TLS2_k127_6859972_6 - - - - 0.000000000000000000000000000000000000000000000000000000003681 210.0
TLS2_k127_6859972_7 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000003909 171.0
TLS2_k127_6859972_8 PFAM Pentapeptide repeats (8 copies) - - - 0.000000008347 70.0
TLS2_k127_686936_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 4.22e-290 911.0
TLS2_k127_686936_1 transport - - - 8.204e-276 876.0
TLS2_k127_686936_10 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 315.0
TLS2_k127_686936_11 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 292.0
TLS2_k127_686936_12 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000007832 244.0
TLS2_k127_686936_14 DoxX - - - 0.000000000000000000000000000000000000000000000000001336 187.0
TLS2_k127_686936_15 Cytochrome b/b6/petB K00127 - - 0.000000000000000000000000000000000000000000000000737 187.0
TLS2_k127_686936_16 protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000001957 141.0
TLS2_k127_686936_17 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000003823 116.0
TLS2_k127_686936_2 PFAM Radical SAM - - - 1.852e-251 783.0
TLS2_k127_686936_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 514.0
TLS2_k127_686936_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 413.0
TLS2_k127_686936_5 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 395.0
TLS2_k127_686936_6 carboxylic ester hydrolase activity K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 393.0
TLS2_k127_686936_7 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 342.0
TLS2_k127_686936_8 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 325.0
TLS2_k127_686936_9 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 334.0
TLS2_k127_6890668_0 TonB-dependent receptor - - - 0.0 1230.0
TLS2_k127_6890668_1 Sodium:neurotransmitter symporter family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 613.0
TLS2_k127_6890668_10 - - - - 0.0000000036 62.0
TLS2_k127_6890668_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 595.0
TLS2_k127_6890668_3 2-keto-3-deoxy-L-rhamnonate aldolase activity K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 289.0
TLS2_k127_6890668_4 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002079 264.0
TLS2_k127_6890668_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000004732 213.0
TLS2_k127_6890668_6 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000000000000001921 171.0
TLS2_k127_6890668_7 DinB superfamily - - - 0.00000000000000000000000000000001304 133.0
TLS2_k127_6890668_9 NfeD-like C-terminal, partner-binding - - - 0.00000000000133 73.0
TLS2_k127_6893218_0 sodium:proton antiporter activity K06382 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 440.0
TLS2_k127_6896427_0 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.000000000000000000000000000000000000000000000000000000002416 211.0
TLS2_k127_6896427_1 ROK family - - - 0.000000000000000000000000000000000000000005356 170.0
TLS2_k127_6896427_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000001825 138.0
TLS2_k127_6901933_0 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000419 248.0
TLS2_k127_6901933_1 Bacterial regulatory proteins, gntR family - - - 0.0000000000000000000000000000000000000000000000000000002079 213.0
TLS2_k127_6901933_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.00000000000000000000000000000000000000000002856 165.0
TLS2_k127_6901933_3 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000004896 168.0
TLS2_k127_6901933_4 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000005145 166.0
TLS2_k127_6901933_5 toxin-antitoxin pair type II binding - - - 0.0000000000000000002331 90.0
TLS2_k127_6910798_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - 0.00000000000000000000000000000000000000000000000000000007461 214.0
TLS2_k127_6910798_1 Initiator Replication protein - - - 0.0000000000000000000000000000000000000000000000004897 186.0
TLS2_k127_6910798_2 - - - - 0.00000000000000000000000000002991 123.0
TLS2_k127_6910798_3 EF hand - - - 0.0000000000000003593 87.0
TLS2_k127_6924623_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 454.0
TLS2_k127_6924623_1 glutathione-regulated potassium exporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 421.0
TLS2_k127_6924623_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 388.0
TLS2_k127_6924623_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 285.0
TLS2_k127_6924623_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000166 221.0
TLS2_k127_6924745_0 LysR substrate binding domain K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 392.0
TLS2_k127_6924745_1 Domain of unknown function (DUF2703) - - - 0.000000000000000000000000000000000000000000000000003542 188.0
TLS2_k127_6924745_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000233 159.0
TLS2_k127_6924745_3 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000009779 152.0
TLS2_k127_6929951_0 WD40 domain protein beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000002122 221.0
TLS2_k127_69384_0 exo-alpha-(2->6)-sialidase activity K01179 - 3.2.1.4 1.87e-279 870.0
TLS2_k127_69384_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.745e-240 762.0
TLS2_k127_69384_2 Carboxypeptidase regulatory-like domain - - - 3.79e-225 739.0
TLS2_k127_69384_3 Transcriptional regulator K22293 - - 0.000000000000000000000000000000000000000000000003879 183.0
TLS2_k127_69384_4 Na+/H+ ion antiporter subunit K05569 - - 0.000000000000000000000000000000000000005731 151.0
TLS2_k127_69384_5 - - - - 0.000000000000000000000000161 115.0
TLS2_k127_69384_6 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.0000000000000000000000005138 115.0
TLS2_k127_69384_7 monovalent cation:proton antiporter activity K05571 - - 0.000000000000000000309 91.0
TLS2_k127_69384_8 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000857 53.0
TLS2_k127_69399_0 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 304.0
TLS2_k127_69399_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 290.0
TLS2_k127_69399_2 PFAM Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008008 274.0
TLS2_k127_69399_3 Ribosomal protein L11/L12 K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000005715 235.0
TLS2_k127_69399_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000005593 162.0
TLS2_k127_69399_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000004498 144.0
TLS2_k127_69399_6 Cell division protein ZapA K09888 - - 0.000000000000000001785 97.0
TLS2_k127_69399_7 structural constituent of ribosome K02913 - - 0.00000000000000001358 83.0
TLS2_k127_69399_8 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000008549 86.0
TLS2_k127_69399_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000001725 77.0
TLS2_k127_6954521_0 Cytochrome c - - - 3.778e-281 888.0
TLS2_k127_6954521_1 sulfolactate sulfo-lyase activity K01685,K01708 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008867,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0071704,GO:1901575 4.2.1.42,4.2.1.7 1.24e-246 773.0
TLS2_k127_6954521_10 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000003333 179.0
TLS2_k127_6954521_11 - - - - 0.00000000000000000000000000000000000008749 147.0
TLS2_k127_6954521_12 Uncharacterised protein family (UPF0175) - - - 0.00000000000002 76.0
TLS2_k127_6954521_13 - - - - 0.0002006 48.0
TLS2_k127_6954521_2 dipeptidyl-peptidase activity K06978 - - 2.904e-243 764.0
TLS2_k127_6954521_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 3.54e-207 653.0
TLS2_k127_6954521_4 Putative collagen-binding domain of a collagenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 535.0
TLS2_k127_6954521_5 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 475.0
TLS2_k127_6954521_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 389.0
TLS2_k127_6954521_7 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 383.0
TLS2_k127_6954521_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000003561 222.0
TLS2_k127_6954521_9 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000001016 208.0
TLS2_k127_6972637_0 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 433.0
TLS2_k127_6972637_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 419.0
TLS2_k127_6972637_2 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 383.0
TLS2_k127_6972637_3 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 299.0
TLS2_k127_6972637_4 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000001821 253.0
TLS2_k127_6972637_5 - K06862 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004233 250.0
TLS2_k127_6972637_6 COG3209 Rhs family protein K11021 - - 0.00000000008988 68.0
TLS2_k127_6974612_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 1.355e-218 685.0
TLS2_k127_6974612_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000008958 147.0
TLS2_k127_6977163_0 Phage portal protein lambda family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 345.0
TLS2_k127_6977163_1 Terminase K21512 - 3.1.21.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 337.0
TLS2_k127_6977163_2 - - - - 0.0000000001101 64.0
TLS2_k127_6981062_0 PFAM aminotransferase, class I K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 584.0
TLS2_k127_6981062_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000005223 243.0
TLS2_k127_6989466_0 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 525.0
TLS2_k127_6989466_1 PFAM peptidase M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 497.0
TLS2_k127_6989466_2 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000001087 124.0
TLS2_k127_6993005_0 Cytochrome c - - - 0.0 1065.0
TLS2_k127_6993005_1 Protein of unknown function (DUF1501) - - - 4.702e-254 789.0
TLS2_k127_6993005_10 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 486.0
TLS2_k127_6993005_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 402.0
TLS2_k127_6993005_12 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 392.0
TLS2_k127_6993005_13 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000006514 205.0
TLS2_k127_6993005_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000002428 203.0
TLS2_k127_6993005_15 SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000175 195.0
TLS2_k127_6993005_16 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000001224 179.0
TLS2_k127_6993005_17 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000000000000000003662 158.0
TLS2_k127_6993005_18 Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000008818 128.0
TLS2_k127_6993005_19 ECF sigma factor K03088 - - 0.000000000000000000001731 102.0
TLS2_k127_6993005_2 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 610.0
TLS2_k127_6993005_20 - - - - 0.0000005513 51.0
TLS2_k127_6993005_21 Beta-lactamase class C and other penicillin binding - - - 0.00004773 53.0
TLS2_k127_6993005_22 Heavy-metal resistance - - - 0.00005975 54.0
TLS2_k127_6993005_3 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 599.0
TLS2_k127_6993005_4 Pyrrolo-quinoline quinone K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 585.0
TLS2_k127_6993005_5 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 561.0
TLS2_k127_6993005_6 CoA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 523.0
TLS2_k127_6993005_7 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 516.0
TLS2_k127_6993005_8 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 517.0
TLS2_k127_6993005_9 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 499.0
TLS2_k127_6996517_0 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000001029 260.0
TLS2_k127_6999223_0 Sucrose phosphate synthase, sucrose phosphatase-like K00696 - 2.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 485.0
TLS2_k127_6999223_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007609 290.0
TLS2_k127_6999223_2 PfkB domain protein K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005725 273.0
TLS2_k127_6999223_3 - - - - 0.000000000000000000000000000000000000000002264 159.0
TLS2_k127_7030837_0 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 453.0
TLS2_k127_7030837_1 Putative serine dehydratase domain K01753 - 4.3.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 371.0
TLS2_k127_7030837_2 PFAM SAF domain K02279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001289 255.0
TLS2_k127_7030837_3 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000003763 169.0
TLS2_k127_7030837_4 AAA domain K02282 - - 0.0000000000000000000000000000000000000001167 160.0
TLS2_k127_7030837_6 - - - - 0.0000000000000000000000001952 117.0
TLS2_k127_704007_0 ATP:ADP antiporter activity K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 529.0
TLS2_k127_704007_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 403.0
TLS2_k127_704007_2 peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 352.0
TLS2_k127_704007_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001848 225.0
TLS2_k127_704007_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000001254 199.0
TLS2_k127_704007_5 cyclic nucleotide binding K00384,K01999,K07001,K10914 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000003555 193.0
TLS2_k127_704007_6 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.000000000000000000000000000000000000000909 149.0
TLS2_k127_704007_7 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000009991 122.0
TLS2_k127_7045330_0 Permease, YjgP YjgQ - - - 1.509e-244 779.0
TLS2_k127_7045330_1 PFAM peptidase U62 modulator of DNA gyrase - - - 4.896e-206 656.0
TLS2_k127_7045330_11 nuclease activity K06218 - - 0.0005285 46.0
TLS2_k127_7045330_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 485.0
TLS2_k127_7045330_3 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 440.0
TLS2_k127_7045330_4 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 293.0
TLS2_k127_7045330_5 transport - - - 0.0000000000000000000000000000000000000001219 157.0
TLS2_k127_7045330_6 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000006678 151.0
TLS2_k127_7045330_7 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000000000000000001831 154.0
TLS2_k127_7045330_9 - - - - 0.00003834 49.0
TLS2_k127_7046662_0 Melibiase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 545.0
TLS2_k127_7046662_1 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 427.0
TLS2_k127_7046662_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 378.0
TLS2_k127_7046662_3 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 369.0
TLS2_k127_7046662_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000001626 219.0
TLS2_k127_7046662_5 - - - - 0.000000000000000000000000000000000000000000000000000004334 196.0
TLS2_k127_7046662_6 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000002216 187.0
TLS2_k127_7046662_7 domain, Protein - - - 0.0000005297 56.0
TLS2_k127_7047047_0 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 506.0
TLS2_k127_7047047_1 PFAM single-strand binding protein Primosomal replication protein n K03111 - - 0.000005833 55.0
TLS2_k127_7047047_2 transposition K03561,K07497 - - 0.0009561 48.0
TLS2_k127_7069164_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 519.0
TLS2_k127_7069164_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 302.0
TLS2_k127_7069164_2 serine-type peptidase activity K03641 - - 0.0000000001748 70.0
TLS2_k127_7072377_0 4-phosphoerythronate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 399.0
TLS2_k127_7072377_1 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 364.0
TLS2_k127_7072377_2 ATP:ADP antiporter activity K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004251 259.0
TLS2_k127_7072377_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000004367 165.0
TLS2_k127_7075875_0 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 458.0
TLS2_k127_7075875_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003325 276.0
TLS2_k127_7075875_2 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002606 269.0
TLS2_k127_7075875_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000001977 162.0
TLS2_k127_7088760_0 PFAM Uncharacterised conserved protein UCP033563 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 464.0
TLS2_k127_7088760_1 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 290.0
TLS2_k127_7088760_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000001051 204.0
TLS2_k127_7088760_3 - - - - 0.000000000000000000000000000000005045 144.0
TLS2_k127_7117141_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 2.497e-206 655.0
TLS2_k127_7117141_1 Pfam:DUF2276 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003427 267.0
TLS2_k127_7126503_0 Amidohydrolase family - - - 3.638e-222 694.0
TLS2_k127_7126503_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 556.0
TLS2_k127_7126503_2 BNR repeat-like domain K05989 - 3.2.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 326.0
TLS2_k127_7137256_0 Dienelactone hydrolase family - - - 0.0 1068.0
TLS2_k127_7137256_1 Cytochrome c, class I - - - 3.121e-236 748.0
TLS2_k127_7137256_10 Protein of unknown function (DUF1175) K09934 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 295.0
TLS2_k127_7137256_11 dextransucrase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002364 265.0
TLS2_k127_7137256_12 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003637 242.0
TLS2_k127_7137256_14 Domain of unknown function (DUF4276) - - - 0.0000000000000000000000000000000000000000000000001624 184.0
TLS2_k127_7137256_15 Beta-L-arabinofuranosidase, GH127 K02169 - 2.1.1.197 0.00000000000000000000000000000000000000003068 173.0
TLS2_k127_7137256_16 Rhomboid family - - - 0.000000000000000000000000000000000000000311 155.0
TLS2_k127_7137256_17 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K01042 - 2.9.1.1 0.000000000000000000000000003216 117.0
TLS2_k127_7137256_18 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000005832 116.0
TLS2_k127_7137256_19 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000461 100.0
TLS2_k127_7137256_2 trisaccharide binding - - - 1.625e-228 727.0
TLS2_k127_7137256_20 tetratricopeptide repeat - - - 0.00000000000000006923 92.0
TLS2_k127_7137256_21 Methyltransferase domain - - - 0.0000000001667 72.0
TLS2_k127_7137256_22 Protein of unknown function (DUF1501) - - - 0.000001142 56.0
TLS2_k127_7137256_23 - - - - 0.000001401 59.0
TLS2_k127_7137256_3 Protein of unknown function (DUF1501) - - - 6.306e-223 708.0
TLS2_k127_7137256_4 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 477.0
TLS2_k127_7137256_5 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 465.0
TLS2_k127_7137256_6 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 477.0
TLS2_k127_7137256_7 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 364.0
TLS2_k127_7137256_8 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 327.0
TLS2_k127_7137256_9 monooxygenase, FAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 308.0
TLS2_k127_7138632_0 peptidyl-tyrosine sulfation - - - 1.115e-224 711.0
TLS2_k127_7138632_1 Arginosuccinate synthase K01940 - 6.3.4.5 4.453e-210 658.0
TLS2_k127_7138632_10 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 473.0
TLS2_k127_7138632_11 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 450.0
TLS2_k127_7138632_12 COG0111 Phosphoglycerate dehydrogenase and related K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 440.0
TLS2_k127_7138632_13 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 411.0
TLS2_k127_7138632_14 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 397.0
TLS2_k127_7138632_15 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 396.0
TLS2_k127_7138632_16 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 355.0
TLS2_k127_7138632_17 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 351.0
TLS2_k127_7138632_18 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 333.0
TLS2_k127_7138632_19 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 301.0
TLS2_k127_7138632_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 624.0
TLS2_k127_7138632_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008857 265.0
TLS2_k127_7138632_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003899 255.0
TLS2_k127_7138632_22 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000000000001696 184.0
TLS2_k127_7138632_23 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000005226 169.0
TLS2_k127_7138632_24 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000003001 177.0
TLS2_k127_7138632_25 Methyltransferase domain K22309 - 2.1.1.344 0.0000000000000000000000000000000000000005868 155.0
TLS2_k127_7138632_27 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000002075 143.0
TLS2_k127_7138632_28 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000469 133.0
TLS2_k127_7138632_29 - - - - 0.000000000000000000000000002585 114.0
TLS2_k127_7138632_3 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 571.0
TLS2_k127_7138632_30 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000004544 126.0
TLS2_k127_7138632_31 Regulatory protein, FmdB - - - 0.000000000000000000002013 96.0
TLS2_k127_7138632_32 determination of stomach left/right asymmetry K10407 - - 0.000000000000000000003194 108.0
TLS2_k127_7138632_33 cAMP biosynthetic process - - - 0.00000000000000000001815 107.0
TLS2_k127_7138632_34 - - - - 0.0000000000000002887 90.0
TLS2_k127_7138632_35 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000001142 85.0
TLS2_k127_7138632_36 acetyltransferase - - - 0.00000000005476 74.0
TLS2_k127_7138632_37 PFAM Sulfate transporter antisigma-factor antagonist STAS K17763 - - 0.000000007557 68.0
TLS2_k127_7138632_38 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.00000008916 63.0
TLS2_k127_7138632_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 552.0
TLS2_k127_7138632_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 552.0
TLS2_k127_7138632_6 'Molybdopterin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 497.0
TLS2_k127_7138632_7 PFAM peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 510.0
TLS2_k127_7138632_8 synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 492.0
TLS2_k127_7138632_9 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 481.0
TLS2_k127_714130_0 Carboxypeptidase regulatory-like domain - - - 0.0 1164.0
TLS2_k127_714130_1 ASPIC and UnbV - - - 4.3e-210 694.0
TLS2_k127_714130_2 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 486.0
TLS2_k127_714130_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 459.0
TLS2_k127_714130_4 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 339.0
TLS2_k127_714130_5 Inosine-uridine preferring nucleoside hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 315.0
TLS2_k127_714130_6 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001804 281.0
TLS2_k127_714130_7 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000004722 88.0
TLS2_k127_714130_8 transposase activity - - - 0.0004218 51.0
TLS2_k127_714166_0 PFAM peptidase K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 339.0
TLS2_k127_714166_1 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002043 243.0
TLS2_k127_714166_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001125 213.0
TLS2_k127_714166_3 transposase activity - - - 0.00000000000000000000000000000000000000000000000123 177.0
TLS2_k127_7146755_0 transport - - - 9.72e-207 681.0
TLS2_k127_7146755_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 477.0
TLS2_k127_7146755_2 deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000002942 248.0
TLS2_k127_7146755_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000245 247.0
TLS2_k127_7146755_4 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000006639 214.0
TLS2_k127_7146755_5 Surface antigen - - - 0.00000000000004269 81.0
TLS2_k127_7166627_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 396.0
TLS2_k127_7166627_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005826 257.0
TLS2_k127_7166627_2 CBD_II - - - 0.00000000000000000000000000000000000000000000000000000000001877 226.0
TLS2_k127_7177191_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 478.0
TLS2_k127_7177191_1 ASPIC and UnbV - - - 0.000000000000000000000000256 107.0
TLS2_k127_718258_0 GMC oxidoreductase - - - 4.725e-256 803.0
TLS2_k127_718258_1 cobalamin-transporting ATPase activity K02014,K16092 - - 1.264e-227 730.0
TLS2_k127_718258_2 helicase superfamily c-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 475.0
TLS2_k127_718258_3 Region found in RelA / SpoT proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000007253 243.0
TLS2_k127_718258_4 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000001723 226.0
TLS2_k127_718258_5 helicase superfamily c-terminal domain - - - 0.00000000000000000000000000000000000000000008194 169.0
TLS2_k127_718258_6 DoxX-like family - - - 0.0000000000000000000000000000000003135 138.0
TLS2_k127_718258_7 Signal Transduction Histidine Kinase K03320 - - 0.00000000000002519 81.0
TLS2_k127_718258_8 - - - - 0.0001799 49.0
TLS2_k127_7189124_0 Cytochrome c - - - 2.78e-318 997.0
TLS2_k127_7189124_1 Protein of unknown function (DUF1501) - - - 9.09e-241 753.0
TLS2_k127_7189124_2 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 485.0
TLS2_k127_7189124_3 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 452.0
TLS2_k127_7189124_4 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 310.0
TLS2_k127_7189124_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000002583 261.0
TLS2_k127_7189124_6 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000007333 232.0
TLS2_k127_7189124_7 PFAM thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000004973 173.0
TLS2_k127_7189124_8 Histidine kinase - - - 0.000000000000000000009495 96.0
TLS2_k127_7189124_9 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000001791 68.0
TLS2_k127_7198291_0 DNA topological change - - - 1.206e-307 960.0
TLS2_k127_7198291_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 412.0
TLS2_k127_7198291_2 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 405.0
TLS2_k127_7198291_3 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000000000000000001372 138.0
TLS2_k127_7198291_4 Protein of unknown function (DUF3018) - - - 0.0000000000005215 74.0
TLS2_k127_720692_0 AAA ATPase domain - - - 3.896e-254 828.0
TLS2_k127_720692_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 586.0
TLS2_k127_720692_2 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' K02293 - 1.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 552.0
TLS2_k127_720692_3 gluconolactonase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 502.0
TLS2_k127_720692_4 domain, Protein K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 376.0
TLS2_k127_720692_5 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001168 282.0
TLS2_k127_720692_6 - - - - 0.000000000000000000000000000000000000000000000000000005656 199.0
TLS2_k127_720692_7 Sh3 type 3 domain protein - - - 0.0000000000000000000000001681 124.0
TLS2_k127_720692_8 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000002685 106.0
TLS2_k127_720692_9 Diguanylate cyclase - - - 0.000000000001412 74.0
TLS2_k127_7209553_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 577.0
TLS2_k127_7232553_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 552.0
TLS2_k127_7232553_1 serine-type peptidase activity K06978,K21105 - 3.1.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 392.0
TLS2_k127_7232553_2 PIN domain K07064 - - 0.00000000000000000000000002878 113.0
TLS2_k127_7232553_3 Carboxypeptidase regulatory-like domain - - - 0.000000000003676 71.0
TLS2_k127_7232553_4 toxin-antitoxin pair type II binding - - - 0.000000000006104 74.0
TLS2_k127_7236755_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 508.0
TLS2_k127_7236755_1 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 504.0
TLS2_k127_7236755_2 alpha-glucuronidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 443.0
TLS2_k127_7236755_3 Zn-dependent peptidases K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 450.0
TLS2_k127_7236755_4 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 297.0
TLS2_k127_7236755_5 Multidrug Resistance protein K11741 - - 0.000000000000000000000000000000000000000000000142 173.0
TLS2_k127_7236755_6 repeat-containing protein - - - 0.0000000000000001718 93.0
TLS2_k127_7236755_8 2 iron, 2 sulfur cluster binding - - - 0.0000001472 59.0
TLS2_k127_7236755_9 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00004962 53.0
TLS2_k127_7255398_0 Protein of unknown function (DUF1501) - - - 1.988e-230 721.0
TLS2_k127_7255398_1 Asparaginase K01444 - 3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 443.0
TLS2_k127_7255398_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 377.0
TLS2_k127_7255398_3 Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 317.0
TLS2_k127_7270277_0 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 584.0
TLS2_k127_7270277_1 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000316 225.0
TLS2_k127_7271447_0 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 304.0
TLS2_k127_7271447_1 Acylphosphatase K04656 - - 0.0000000000000000000000000000000000000001975 153.0
TLS2_k127_7271447_2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000000002839 121.0
TLS2_k127_728074_0 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01684 - 4.2.1.6 2.062e-197 623.0
TLS2_k127_728074_1 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 454.0
TLS2_k127_728074_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 300.0
TLS2_k127_728074_3 tyrosinase K00505 - 1.14.18.1 0.000000000000000000000000000000000000000000000000000003799 205.0
TLS2_k127_728074_4 - - - - 0.0000000000000000000000004433 115.0
TLS2_k127_7285033_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1575.0
TLS2_k127_7285033_1 Fad linked oxidase - - - 3.43e-242 757.0
TLS2_k127_7285033_2 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006486 242.0
TLS2_k127_7285033_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000001004 174.0
TLS2_k127_7285033_4 PFAM Rv0623 family protein transcription factor K19687 - - 0.00001217 55.0
TLS2_k127_728814_0 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 405.0
TLS2_k127_728814_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 297.0
TLS2_k127_7296400_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.405e-272 851.0
TLS2_k127_7296400_1 PQQ-like domain K00114 - 1.1.2.8 3.899e-225 711.0
TLS2_k127_7296400_2 Di-haem cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 410.0
TLS2_k127_7296400_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002741 290.0
TLS2_k127_7296400_4 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002958 259.0
TLS2_k127_7296400_5 Cytochrome c - - - 0.00000000000000000000000001721 112.0
TLS2_k127_730607_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 5.006e-229 730.0
TLS2_k127_730607_1 Protein of unknown function (DUF1501) - - - 8.071e-203 639.0
TLS2_k127_730607_2 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 500.0
TLS2_k127_730607_3 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 421.0
TLS2_k127_730607_4 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 371.0
TLS2_k127_730607_5 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001657 278.0
TLS2_k127_730607_6 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007927 272.0
TLS2_k127_7312444_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.067e-194 644.0
TLS2_k127_7312444_1 PFAM Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 578.0
TLS2_k127_7312444_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 445.0
TLS2_k127_7312444_3 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 430.0
TLS2_k127_7312444_4 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 383.0
TLS2_k127_7312444_5 arylformamidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 364.0
TLS2_k127_7312444_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 327.0
TLS2_k127_7312444_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 327.0
TLS2_k127_7312444_8 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000005036 188.0
TLS2_k127_7323804_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 6.966e-274 856.0
TLS2_k127_7323804_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 348.0
TLS2_k127_7323804_2 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 290.0
TLS2_k127_7323804_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 302.0
TLS2_k127_7323804_4 Transport and Golgi organisation 2 K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000082 211.0
TLS2_k127_7323804_5 Bestrophin, RFP-TM, chloride channel K08994 - - 0.00000000000000000000000004279 112.0
TLS2_k127_7325335_0 Carboxypeptidase regulatory-like domain - - - 9.954e-248 805.0
TLS2_k127_7325335_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000003714 250.0
TLS2_k127_73368_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.661e-291 907.0
TLS2_k127_73368_1 membrane organization K07277,K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 626.0
TLS2_k127_73368_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 601.0
TLS2_k127_73368_3 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 534.0
TLS2_k127_73368_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 396.0
TLS2_k127_73368_5 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000006275 247.0
TLS2_k127_7344998_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.428e-235 737.0
TLS2_k127_7344998_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 407.0
TLS2_k127_7344998_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000001593 209.0
TLS2_k127_7344998_11 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000001547 202.0
TLS2_k127_7344998_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000003019 198.0
TLS2_k127_7344998_13 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000002575 191.0
TLS2_k127_7344998_14 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000003711 143.0
TLS2_k127_7344998_15 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000006118 148.0
TLS2_k127_7344998_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000001527 117.0
TLS2_k127_7344998_17 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000007321 98.0
TLS2_k127_7344998_18 Ribosomal protein L30 K02907 - - 0.0000000000000009141 79.0
TLS2_k127_7344998_19 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001773 67.0
TLS2_k127_7344998_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 295.0
TLS2_k127_7344998_20 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000004596 69.0
TLS2_k127_7344998_21 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000002209 60.0
TLS2_k127_7344998_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 294.0
TLS2_k127_7344998_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 290.0
TLS2_k127_7344998_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000006133 261.0
TLS2_k127_7344998_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002023 248.0
TLS2_k127_7344998_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004762 245.0
TLS2_k127_7344998_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000001046 227.0
TLS2_k127_7344998_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000008465 218.0
TLS2_k127_7350943_0 Peptidase family M28 - - - 1.1e-230 726.0
TLS2_k127_7350943_1 Carboxypeptidase regulatory-like domain - - - 3.52e-218 691.0
TLS2_k127_7350943_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 472.0
TLS2_k127_7350943_3 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 451.0
TLS2_k127_7350943_4 transglutaminase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 315.0
TLS2_k127_7350943_5 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000002069 164.0
TLS2_k127_735121_0 Protein of unknown function (DUF1501) - - - 9.676e-226 706.0
TLS2_k127_735121_1 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 426.0
TLS2_k127_735121_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 420.0
TLS2_k127_735121_3 - - - - 0.0000000000000000000000000000008941 130.0
TLS2_k127_735121_4 - - - - 0.000000000000000000000000000006919 121.0
TLS2_k127_7353702_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.835e-222 704.0
TLS2_k127_7353702_1 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 419.0
TLS2_k127_7353702_2 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 374.0
TLS2_k127_7353702_3 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 314.0
TLS2_k127_7353702_4 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002144 248.0
TLS2_k127_7353702_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000005631 78.0
TLS2_k127_7357116_0 protocatechuate 3,4-dioxygenase activity - - - 0.0 1354.0
TLS2_k127_7357116_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.733e-225 715.0
TLS2_k127_7357116_2 TPR repeat - - - 6.262e-212 687.0
TLS2_k127_7357116_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 601.0
TLS2_k127_7357116_4 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006507 289.0
TLS2_k127_7357116_5 FCD - - - 0.0000000000000000000000000000000000000000000001569 177.0
TLS2_k127_7357116_6 cAMP biosynthetic process K03765,K07277,K07316,K21008 - 2.1.1.72 0.0000000000000000000000000000006966 137.0
TLS2_k127_7357116_7 proteolysis - - - 0.000003286 52.0
TLS2_k127_736457_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.332e-263 833.0
TLS2_k127_736457_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000113 282.0
TLS2_k127_736457_2 InterPro IPR007367 - - - 0.00000000000000000000000000000000000000000000002287 181.0
TLS2_k127_736457_3 Polysaccharide lyase family 4, domain III - - - 0.000000000000000000000000000000000000000008438 177.0
TLS2_k127_736457_4 - - - - 0.000000000000000000000000000000004634 137.0
TLS2_k127_736457_5 TonB-dependent receptor - - - 0.0000000000000000000000006507 111.0
TLS2_k127_736457_7 PAAR motif - - - 0.0000000006076 68.0
TLS2_k127_7369052_0 Chase2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 476.0
TLS2_k127_7369052_1 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 417.0
TLS2_k127_7369052_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 389.0
TLS2_k127_7369052_3 aldo keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 377.0
TLS2_k127_7369052_4 methyltransferase - - - 0.000000000000000000000000000000000000000000000000007281 186.0
TLS2_k127_7369052_5 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000008068 176.0
TLS2_k127_7369052_6 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.00000000000000000000000005115 109.0
TLS2_k127_7369052_7 - - - - 0.0007329 49.0
TLS2_k127_7380384_0 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 2.344e-196 625.0
TLS2_k127_7380384_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 501.0
TLS2_k127_7380384_2 - - - - 0.0000000000000000000000000000000000000001533 158.0
TLS2_k127_7380384_3 - - - - 0.000000000000000000000000001524 116.0
TLS2_k127_7388935_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.632e-293 915.0
TLS2_k127_7388935_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 458.0
TLS2_k127_7388935_2 transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 458.0
TLS2_k127_7388935_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000001976 94.0
TLS2_k127_7410094_0 phage tail tape measure protein K02487,K03646,K07192,K13582 - - 1.497e-227 764.0
TLS2_k127_7410094_1 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 582.0
TLS2_k127_7410094_2 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 314.0
TLS2_k127_7410094_3 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 319.0
TLS2_k127_7410094_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009077 274.0
TLS2_k127_7410094_5 - - - - 0.0000000000000000000000000000000006431 139.0
TLS2_k127_7410094_6 positive regulation of growth rate - GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 - 0.000000000000000000000000003539 113.0
TLS2_k127_7410094_7 Phage tail sheath protein subtilisin-like domain K06907 - - 0.00000000000006958 71.0
TLS2_k127_7410094_8 Late control gene D protein - - - 0.0000000000002778 72.0
TLS2_k127_7423793_0 Glycosyl transferase family group 2 K11740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 546.0
TLS2_k127_7423793_1 protocatechuate 3,4-dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 306.0
TLS2_k127_7423793_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 283.0
TLS2_k127_7423793_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000683 286.0
TLS2_k127_7423793_4 protocatechuate 3,4-dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003039 269.0
TLS2_k127_7423793_5 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000002274 248.0
TLS2_k127_7423793_6 Tetratricopeptide repeat - - - 0.00000000000000000000000004626 123.0
TLS2_k127_7424096_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.514e-311 973.0
TLS2_k127_7424096_1 Carboxypeptidase regulatory-like domain - - - 2.282e-230 728.0
TLS2_k127_7424096_10 TIR domain - - - 0.0000000000001127 81.0
TLS2_k127_7424096_11 - - - - 0.000000000001539 80.0
TLS2_k127_7424096_2 protocatechuate 3,4-dioxygenase activity - - - 1.703e-203 670.0
TLS2_k127_7424096_3 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 412.0
TLS2_k127_7424096_4 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000003857 203.0
TLS2_k127_7424096_5 Anti-sigma factor - - - 0.0000000000000000000000000000000000000000000000000001223 208.0
TLS2_k127_7424096_6 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000004662 175.0
TLS2_k127_7424096_7 region 4 type 2 K03088 - - 0.00000000000000000000000000000000000000001304 160.0
TLS2_k127_7424096_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000004406 118.0
TLS2_k127_7433901_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 543.0
TLS2_k127_7433901_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 451.0
TLS2_k127_7433901_2 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000001532 210.0
TLS2_k127_7433901_3 energy transducer activity K03832 - - 0.000000000000000000000000000000000000000000000005918 190.0
TLS2_k127_7433901_4 Transcription termination factor nusG - - - 0.000000000000000000000000000000000001042 147.0
TLS2_k127_7433901_5 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000000000009393 124.0
TLS2_k127_7435472_0 carboxylic acid catabolic process K01706 - 4.2.1.40 1.659e-211 664.0
TLS2_k127_7435472_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 596.0
TLS2_k127_7435472_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 551.0
TLS2_k127_7435472_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01707 - 4.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 454.0
TLS2_k127_7435472_4 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 291.0
TLS2_k127_7435472_5 Ferric uptake regulator family K09825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001492 257.0
TLS2_k127_7435472_6 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000128 246.0
TLS2_k127_7435472_7 TPR repeat - - - 0.000000000000000000000000000000000000000000000007041 188.0
TLS2_k127_7435472_8 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000004665 132.0
TLS2_k127_762548_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503,K13950 - 2.6.1.85,4.1.3.27 9.106e-210 659.0
TLS2_k127_762548_1 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 382.0
TLS2_k127_762548_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000003996 229.0
TLS2_k127_762548_3 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000004431 203.0
TLS2_k127_767749_0 PHP domain protein - - - 0.0 1023.0
TLS2_k127_767749_1 glutaminase activity K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0040008,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0045926,GO:0046394,GO:0046395,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 471.0
TLS2_k127_767749_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 350.0
TLS2_k127_767749_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 327.0
TLS2_k127_784758_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 5.724e-319 991.0
TLS2_k127_784758_1 cobalamin-transporting ATPase activity K02014 - - 6.219e-204 654.0
TLS2_k127_784758_10 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000001253 154.0
TLS2_k127_784758_11 - - - - 0.00000000000000000000001569 105.0
TLS2_k127_784758_12 negative regulation of transcription, DNA-templated - - - 0.000000000000000000006134 96.0
TLS2_k127_784758_13 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000002504 81.0
TLS2_k127_784758_14 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.00000000004359 70.0
TLS2_k127_784758_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 526.0
TLS2_k127_784758_3 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 362.0
TLS2_k127_784758_4 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 331.0
TLS2_k127_784758_5 protein kinase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 303.0
TLS2_k127_784758_6 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001524 283.0
TLS2_k127_784758_7 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009666 258.0
TLS2_k127_784758_8 hemolysin - - - 0.00000000000000000000000000000000000000000000000000000000001283 217.0
TLS2_k127_784758_9 Diacylglycerol kinase catalytic domain (presumed) - - - 0.000000000000000000000000000000000000000000000001921 190.0
TLS2_k127_787768_0 Aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 2.8e-242 755.0
TLS2_k127_787768_1 Elongation factor SelB, winged helix K03833 - - 6.913e-226 716.0
TLS2_k127_787768_10 Bacterial PH domain - - - 0.000000000000000008798 87.0
TLS2_k127_787768_11 Rv0623-like transcription factor - - - 0.0000002526 55.0
TLS2_k127_787768_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 303.0
TLS2_k127_787768_3 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 309.0
TLS2_k127_787768_4 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000006402 211.0
TLS2_k127_787768_5 - - - - 0.000000000000000000000000000000000000000000000000000007337 201.0
TLS2_k127_787768_6 VWA domain containing CoxE-like protein - - - 0.00000000000000000000000000000000000000000000000000007032 207.0
TLS2_k127_787768_7 DinB family - - - 0.0000000000000000000000000000000000000000003159 164.0
TLS2_k127_787768_8 Domain of unknown function (DUF4281) - - - 0.000000000000000000000000000000000000000008075 162.0
TLS2_k127_787768_9 Prion-inhibition and propagation - - - 0.00000000000000000000000000000000000005543 157.0
TLS2_k127_797617_0 Carboxypeptidase regulatory-like domain - - - 0.0 1073.0
TLS2_k127_797617_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 512.0
TLS2_k127_797617_2 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 466.0
TLS2_k127_797617_3 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 429.0
TLS2_k127_797617_4 S1/P1 Nuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000001433 245.0
TLS2_k127_797617_5 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000002736 154.0
TLS2_k127_797617_7 Protein of unknown function (DUF3386) - - - 0.000000003343 67.0
TLS2_k127_804448_0 Tetratricopeptide repeats - - - 1.03e-255 812.0
TLS2_k127_804448_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 538.0
TLS2_k127_804448_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 459.0
TLS2_k127_804448_3 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 331.0
TLS2_k127_804448_4 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000356 165.0
TLS2_k127_807685_0 TonB-dependent receptor - - - 6.87e-322 1021.0
TLS2_k127_807685_1 Protein of unknown function (DUF1501) - - - 2.493e-247 773.0
TLS2_k127_807685_10 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003023 277.0
TLS2_k127_807685_11 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000001418 246.0
TLS2_k127_807685_12 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000022 232.0
TLS2_k127_807685_13 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000001571 203.0
TLS2_k127_807685_14 Probable cobalt transporter subunit (CbtA) - - - 0.000000000000000000000000000000000000000007703 163.0
TLS2_k127_807685_15 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000008664 151.0
TLS2_k127_807685_16 CobN/Magnesium Chelatase K02230 - 6.6.1.2 0.00000000000000000000000000000000002521 140.0
TLS2_k127_807685_17 Nitrile hydratase beta subunit - - - 0.000000000000000000000000000000002553 137.0
TLS2_k127_807685_18 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000001483 119.0
TLS2_k127_807685_19 Probable cobalt transporter subunit (CbtB) - - - 0.0000000001513 63.0
TLS2_k127_807685_2 COG3119 Arylsulfatase A K01137 - 3.1.6.14 1.05e-210 666.0
TLS2_k127_807685_20 PFAM transposase IS116 IS110 IS902 family protein K07486 - - 0.000000008067 68.0
TLS2_k127_807685_21 Transposase IS116 IS110 IS902 - - - 0.000596 52.0
TLS2_k127_807685_3 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.372e-209 661.0
TLS2_k127_807685_4 metal-sulfur cluster biosynthetic enzyme K02612 - - 4.749e-196 630.0
TLS2_k127_807685_5 Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 459.0
TLS2_k127_807685_6 Nitrile hydratase, alpha chain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 335.0
TLS2_k127_807685_7 domain, Protein K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 326.0
TLS2_k127_807685_8 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 303.0
TLS2_k127_807685_9 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003241 278.0
TLS2_k127_823011_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1309.0
TLS2_k127_823011_1 Carboxypeptidase regulatory-like domain - - - 0.0 1038.0
TLS2_k127_823011_10 amine dehydrogenase activity K12287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 313.0
TLS2_k127_823011_11 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 309.0
TLS2_k127_823011_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004756 252.0
TLS2_k127_823011_13 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000001721 238.0
TLS2_k127_823011_14 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000003488 230.0
TLS2_k127_823011_15 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000003565 234.0
TLS2_k127_823011_16 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000001436 219.0
TLS2_k127_823011_17 - - - - 0.00000000000000000000000000000000000000000000000000366 191.0
TLS2_k127_823011_18 - - - - 0.0000000000000000000000000000000000000000000000005407 185.0
TLS2_k127_823011_19 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000001143 162.0
TLS2_k127_823011_2 Carboxypeptidase regulatory-like domain - - - 7.147e-305 964.0
TLS2_k127_823011_20 Putative zinc-finger - - - 0.0000000000000000000000000000000001184 143.0
TLS2_k127_823011_21 Peptidase C13 family - - - 0.0000000000000000000000000002072 130.0
TLS2_k127_823011_22 Carboxypeptidase regulatory-like domain - - - 0.000000000000000002704 88.0
TLS2_k127_823011_23 Von Willebrand factor A domain-containing protein 7-like - - - 0.0000000000000002665 92.0
TLS2_k127_823011_26 - - - - 0.000001285 59.0
TLS2_k127_823011_27 Protein of unknown function (DUF1318) K09978 - - 0.00002267 55.0
TLS2_k127_823011_28 domain, Protein - - - 0.0008038 46.0
TLS2_k127_823011_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.815e-266 828.0
TLS2_k127_823011_4 - - - - 4.95e-228 741.0
TLS2_k127_823011_5 Belongs to the malate synthase family K01638 - 2.3.3.9 1.031e-217 681.0
TLS2_k127_823011_6 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 610.0
TLS2_k127_823011_7 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 404.0
TLS2_k127_823011_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 367.0
TLS2_k127_823011_9 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 345.0
TLS2_k127_878721_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 321.0
TLS2_k127_878721_1 domain, Protein - - - 0.00000000000000000000000000000000002571 155.0
TLS2_k127_898492_0 Protein of unknown function (DUF1549) - - - 1.101e-263 850.0
TLS2_k127_898492_1 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 2.827e-249 808.0
TLS2_k127_898492_10 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 424.0
TLS2_k127_898492_11 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 424.0
TLS2_k127_898492_12 SRP54-type protein, GTPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 399.0
TLS2_k127_898492_13 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 360.0
TLS2_k127_898492_14 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 344.0
TLS2_k127_898492_15 AAA domain K08252 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 334.0
TLS2_k127_898492_16 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 327.0
TLS2_k127_898492_17 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 309.0
TLS2_k127_898492_18 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 343.0
TLS2_k127_898492_19 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001628 293.0
TLS2_k127_898492_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.642e-227 711.0
TLS2_k127_898492_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002419 259.0
TLS2_k127_898492_21 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003234 262.0
TLS2_k127_898492_22 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000006805 238.0
TLS2_k127_898492_23 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000000000002118 233.0
TLS2_k127_898492_24 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000007615 225.0
TLS2_k127_898492_25 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000003479 237.0
TLS2_k127_898492_26 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000115 202.0
TLS2_k127_898492_27 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000002532 202.0
TLS2_k127_898492_28 EVE domain - - - 0.0000000000000000000000000000000000000000000000006233 177.0
TLS2_k127_898492_29 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000005275 170.0
TLS2_k127_898492_3 Protein of unknown function DUF116 - - - 1.26e-214 681.0
TLS2_k127_898492_30 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000001021 175.0
TLS2_k127_898492_31 TM2 domain - - - 0.0000000000000000000000000000000000000004424 154.0
TLS2_k127_898492_32 cobalamin-transporting ATPase activity - - - 0.0000000000000000000000000000000000003801 147.0
TLS2_k127_898492_33 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000009145 155.0
TLS2_k127_898492_34 - - - - 0.000000000000000000000000000000001709 133.0
TLS2_k127_898492_35 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000001457 118.0
TLS2_k127_898492_36 Protein of unknown function (DUF721) - - - 0.000000000000000000000012 107.0
TLS2_k127_898492_37 PFAM NHL repeat containing protein - - - 0.000000000000000002431 95.0
TLS2_k127_898492_39 - - - - 0.0000000001065 72.0
TLS2_k127_898492_4 Protein of unknown function (DUF1501) - - - 2.943e-197 625.0
TLS2_k127_898492_5 Squalene-hopene cyclase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 616.0
TLS2_k127_898492_6 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 543.0
TLS2_k127_898492_7 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 459.0
TLS2_k127_898492_8 Belongs to the peptidase S8 family K14647 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 473.0
TLS2_k127_898492_9 PFAM Mandelate racemase muconate lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 445.0
TLS2_k127_904168_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1155.0
TLS2_k127_904168_1 Carboxypeptidase regulatory-like domain - - - 9.524e-298 949.0
TLS2_k127_904168_10 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 527.0
TLS2_k127_904168_11 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 495.0
TLS2_k127_904168_12 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 494.0
TLS2_k127_904168_13 arylsulfatase activity K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 491.0
TLS2_k127_904168_14 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 487.0
TLS2_k127_904168_15 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 470.0
TLS2_k127_904168_16 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 467.0
TLS2_k127_904168_17 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 458.0
TLS2_k127_904168_18 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 448.0
TLS2_k127_904168_19 Outer membrane protein beta-barrel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 433.0
TLS2_k127_904168_2 GMC oxidoreductase - - - 5.807e-236 739.0
TLS2_k127_904168_20 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 377.0
TLS2_k127_904168_21 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 397.0
TLS2_k127_904168_22 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 368.0
TLS2_k127_904168_23 Transcriptional regulatory protein, C terminal K02483,K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 352.0
TLS2_k127_904168_24 OmpA family K02557,K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 364.0
TLS2_k127_904168_25 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 354.0
TLS2_k127_904168_26 CBD_II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 350.0
TLS2_k127_904168_27 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 332.0
TLS2_k127_904168_28 Sigma-70, region 4 K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 316.0
TLS2_k127_904168_29 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 306.0
TLS2_k127_904168_3 Isocitrate/isopropylmalate dehydrogenase - - - 1.371e-221 696.0
TLS2_k127_904168_30 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 301.0
TLS2_k127_904168_31 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000001109 236.0
TLS2_k127_904168_32 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000003218 224.0
TLS2_k127_904168_33 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000003439 206.0
TLS2_k127_904168_34 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.000000000000000000000000000000000000000000000000000000004948 211.0
TLS2_k127_904168_35 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000001115 207.0
TLS2_k127_904168_36 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000005998 201.0
TLS2_k127_904168_37 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000003511 213.0
TLS2_k127_904168_38 TIGRFAM Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000215 176.0
TLS2_k127_904168_39 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000001971 177.0
TLS2_k127_904168_4 SpoIVB peptidase S55 - - - 5.001e-218 694.0
TLS2_k127_904168_41 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000001592 143.0
TLS2_k127_904168_42 - - - - 0.000000000000000000000000000000000002707 140.0
TLS2_k127_904168_43 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000006077 140.0
TLS2_k127_904168_44 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000008188 135.0
TLS2_k127_904168_45 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.0000000000000000000000000000000006061 133.0
TLS2_k127_904168_46 Belongs to the peptidase S41A family - - - 0.00000000000000000000000000000000471 139.0
TLS2_k127_904168_47 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000007978 130.0
TLS2_k127_904168_48 Response regulator, receiver - - - 0.000000000000000000000000000003321 126.0
TLS2_k127_904168_49 - - - - 0.00000000000000000000000000002276 123.0
TLS2_k127_904168_5 PFAM SMP-30 Gluconolaconase - - - 4.927e-214 687.0
TLS2_k127_904168_50 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000001328 119.0
TLS2_k127_904168_51 Protein conserved in bacteria - - - 0.0000000000000000000004675 103.0
TLS2_k127_904168_52 GlcNAc-PI de-N-acetylase K22408 - - 0.000000000004482 77.0
TLS2_k127_904168_53 von Willebrand factor, type A K07114 - - 0.0000000003499 71.0
TLS2_k127_904168_54 COG NOG06100 non supervised orthologous group - - - 0.00000002067 66.0
TLS2_k127_904168_55 - - - - 0.0000005439 53.0
TLS2_k127_904168_6 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 7.923e-197 622.0
TLS2_k127_904168_7 TIGRFAM KamA family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 608.0
TLS2_k127_904168_8 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 589.0
TLS2_k127_904168_9 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 564.0
TLS2_k127_920618_0 domain, Protein K20276 - - 5.549e-313 983.0
TLS2_k127_920618_1 UvrD/REP helicase N-terminal domain - - - 4.888e-286 917.0
TLS2_k127_920618_10 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 350.0
TLS2_k127_920618_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006859 296.0
TLS2_k127_920618_12 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000182 139.0
TLS2_k127_920618_13 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000002469 129.0
TLS2_k127_920618_14 peroxiredoxin activity - - - 0.000000000000000000000000000000104 136.0
TLS2_k127_920618_15 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000001189 95.0
TLS2_k127_920618_16 addiction module antidote protein - - - 0.000000000000000004513 93.0
TLS2_k127_920618_17 Surface antigen - - - 0.00000002553 66.0
TLS2_k127_920618_2 Belongs to the helicase family. UvrD subfamily K03169,K16899 - 3.6.4.12,5.99.1.2 8.483e-220 722.0
TLS2_k127_920618_3 Protein of unknown function (DUF1501) - - - 2.822e-201 634.0
TLS2_k127_920618_4 Y_Y_Y domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 595.0
TLS2_k127_920618_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 481.0
TLS2_k127_920618_6 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 432.0
TLS2_k127_920618_7 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 407.0
TLS2_k127_920618_8 translation initiation factor activity K06370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 384.0
TLS2_k127_920618_9 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 358.0
TLS2_k127_922176_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 306.0
TLS2_k127_922176_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000004181 158.0
TLS2_k127_935557_0 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 460.0
TLS2_k127_935557_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 377.0
TLS2_k127_935557_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000001242 194.0
TLS2_k127_935557_3 Domain of Unknown Function (DUF350) - - - 0.00000000000000000000000000000000000000001084 168.0
TLS2_k127_946897_0 Acetolactate synthase, large subunit K01652 - 2.2.1.6 2.204e-292 905.0
TLS2_k127_946897_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 540.0
TLS2_k127_946897_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000001086 246.0
TLS2_k127_946897_3 HDOD domain - - - 0.00000000000000000000000000000000000000003016 162.0
TLS2_k127_946897_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000002345 120.0
TLS2_k127_965240_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 2.973e-281 871.0
TLS2_k127_965240_1 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 493.0
TLS2_k127_965240_2 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 418.0
TLS2_k127_965240_3 DeoC/LacD family aldolase K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000003788 245.0
TLS2_k127_965240_4 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000001135 162.0
TLS2_k127_965240_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000943 66.0
TLS2_k127_965240_6 Stress-inducible protein - - - 0.000004501 60.0
TLS2_k127_987592_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 523.0
TLS2_k127_987592_1 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 292.0
TLS2_k127_987592_2 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000000000004287 212.0
TLS2_k127_988357_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.756e-217 701.0
TLS2_k127_998747_0 3-oxoacyl-[acyl-carrier-protein] synthase activity K06406 - - 6.089e-210 679.0
TLS2_k127_998747_1 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 0.000004761 53.0