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Overview

ID MAG03996
Name TLS2_bin.3
Sample SMP0104
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Bryobacterales
Family UBA6623
Genus
Species
Assembly information
Completeness (%) 80.16
Contamination (%) 3.24
GC content (%) 62.0
N50 (bp) 7,031
Genome size (bp) 4,550,808

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3815

Gene name Description KEGG GOs EC E-value Score Sequence
TLS2_k127_1001326_0 Carboxypeptidase regulatory-like domain - - - 5.178e-236 762.0
TLS2_k127_1001326_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 477.0
TLS2_k127_1001326_2 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000000000000000000000000000008667 224.0
TLS2_k127_1001868_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 9.268e-199 629.0
TLS2_k127_1001868_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 499.0
TLS2_k127_1001868_2 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 340.0
TLS2_k127_1001868_3 - K07403 - - 0.000000000000000000001633 98.0
TLS2_k127_1003610_0 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000007887 257.0
TLS2_k127_1003610_1 - - - - 0.00000000000000000000000000000000000000003402 170.0
TLS2_k127_1003610_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000008587 123.0
TLS2_k127_1005237_0 PFAM Glycosyl transferase, family K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 514.0
TLS2_k127_1005237_1 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 501.0
TLS2_k127_1005237_2 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 356.0
TLS2_k127_1005237_3 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000005677 182.0
TLS2_k127_1005237_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000004143 83.0
TLS2_k127_1005237_5 Hfq protein K03666 - - 0.000000000000003831 81.0
TLS2_k127_1007438_0 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 340.0
TLS2_k127_1007438_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000008868 134.0
TLS2_k127_1013502_0 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000001087 155.0
TLS2_k127_1013502_1 Haem-degrading - - - 0.00000000000000000000000000000000000003266 149.0
TLS2_k127_1013502_2 efflux transmembrane transporter activity - - - 0.0000000000000000000001099 101.0
TLS2_k127_1013502_3 Cupin domain - - - 0.000000000000000000003704 104.0
TLS2_k127_1013502_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.00000004477 57.0
TLS2_k127_1017296_0 siderophore transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 357.0
TLS2_k127_1017296_1 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 312.0
TLS2_k127_1018043_0 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0 1272.0
TLS2_k127_1018043_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 509.0
TLS2_k127_1018043_2 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 310.0
TLS2_k127_1018043_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000009549 176.0
TLS2_k127_1019191_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 5.139e-206 659.0
TLS2_k127_1019191_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 392.0
TLS2_k127_1019191_2 Ribonuclease, Rne Rng family K08301 - - 0.000000000000000000000000000000002344 142.0
TLS2_k127_1019540_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 485.0
TLS2_k127_1019540_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 337.0
TLS2_k127_1019540_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000004379 224.0
TLS2_k127_1019540_3 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000006427 205.0
TLS2_k127_1019540_4 PFAM Abortive infection protein K07052 - - 0.000000000000000000000000000000000000000000005085 177.0
TLS2_k127_1019540_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000006695 173.0
TLS2_k127_1019540_6 competence protein - - - 0.00000000000000000000000000000000001689 145.0
TLS2_k127_1019540_7 Redoxin - - - 0.000000000000000000000000001703 118.0
TLS2_k127_1019540_8 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000005227 119.0
TLS2_k127_1019540_9 Putative zinc-finger - - - 0.00008576 51.0
TLS2_k127_1024003_0 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 464.0
TLS2_k127_1024003_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000002705 138.0
TLS2_k127_1024123_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000004224 204.0
TLS2_k127_1024123_1 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000001 138.0
TLS2_k127_1024123_2 DNA-binding transcription factor activity - - - 0.00000000000000000000000006358 112.0
TLS2_k127_1024123_3 Outer membrane efflux protein - - - 0.00000000000006872 76.0
TLS2_k127_1025320_0 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 398.0
TLS2_k127_1025320_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 379.0
TLS2_k127_1025320_2 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000003924 181.0
TLS2_k127_1025320_3 B domain of TMEM189, localisation domain K20656 - - 0.0000000000000000000000000000000000000001387 158.0
TLS2_k127_1025320_4 (S)-2-hydroxy-acid oxidase K11517 GO:0002218,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006950,GO:0006952,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010204,GO:0016999,GO:0017000,GO:0017144,GO:0023052,GO:0031347,GO:0031349,GO:0042579,GO:0042742,GO:0042743,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0050665,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0072593,GO:0080134,GO:0098542,GO:1903409 1.1.3.15 0.00000000000000000000000000000000003164 145.0
TLS2_k127_1027580_0 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000001163 197.0
TLS2_k127_1027765_0 Carboxypeptidase regulatory-like domain - - - 4.667e-256 826.0
TLS2_k127_1027765_1 Sigma-70 region 3 K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 433.0
TLS2_k127_1027765_2 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 412.0
TLS2_k127_1027765_3 Transcriptional regulator K22293 - - 0.00000000000000000000000000000000000000000000000003626 189.0
TLS2_k127_1027765_4 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000008615 111.0
TLS2_k127_1027765_5 - - - - 0.00000000000000006636 87.0
TLS2_k127_1029372_0 Sigma-54 interaction domain - - - 2.577e-195 621.0
TLS2_k127_1029372_1 mandelate racemase muconate lactonizing K08323 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0047929,GO:0071704,GO:1901575 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 539.0
TLS2_k127_1029372_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 419.0
TLS2_k127_1029372_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000003762 185.0
TLS2_k127_1029372_4 - - - - 0.000000000000000000000131 102.0
TLS2_k127_1033907_0 N-acetyldiaminopimelate deacetylase activity K12941 - - 1.434e-285 885.0
TLS2_k127_1033907_1 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 425.0
TLS2_k127_1033907_2 Oligogalacturonate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000401 226.0
TLS2_k127_1033907_3 toxin-antitoxin pair type II binding - - - 0.00000000000000006384 83.0
TLS2_k127_1033907_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000626 81.0
TLS2_k127_1033907_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000001301 51.0
TLS2_k127_1037945_0 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.0000000000000000002845 97.0
TLS2_k127_1037945_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000002409 83.0
TLS2_k127_1045921_0 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 374.0
TLS2_k127_1045921_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 366.0
TLS2_k127_1045921_2 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002463 237.0
TLS2_k127_1050434_0 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 271.0
TLS2_k127_1050434_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000261 167.0
TLS2_k127_1050434_2 - - - - 0.000000000000000001146 99.0
TLS2_k127_1050434_3 TPR repeat - - - 0.000000000000000005976 90.0
TLS2_k127_1051244_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 310.0
TLS2_k127_1051244_1 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006023 265.0
TLS2_k127_1051244_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000003364 228.0
TLS2_k127_1051244_3 - - - - 0.000000000000000000000000000000002647 134.0
TLS2_k127_1051244_4 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000002278 135.0
TLS2_k127_105167_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 590.0
TLS2_k127_105167_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 411.0
TLS2_k127_105167_2 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 387.0
TLS2_k127_105167_3 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000000001678 187.0
TLS2_k127_105167_4 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000001382 126.0
TLS2_k127_105167_5 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000001074 62.0
TLS2_k127_1065011_0 PQQ enzyme repeat K00117 - 1.1.5.2 5.755e-233 743.0
TLS2_k127_1065011_1 H( )-stimulated, divalent metal cation uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000732 395.0
TLS2_k127_1065011_2 TIGRFAM HAD-superfamily subfamily IIA hydrolase like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 293.0
TLS2_k127_1065011_3 amine dehydrogenase activity K12287 - - 0.000000000000000000000000000000000000000000109 179.0
TLS2_k127_1065011_4 Trehalose utilisation - - - 0.000000000000000000000000000000000002016 157.0
TLS2_k127_1065011_5 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000004772 107.0
TLS2_k127_1065011_6 RNA recognition motif - - - 0.000000000000000000002928 98.0
TLS2_k127_1065011_7 Xylose isomerase-like TIM barrel - - - 0.000000000004546 79.0
TLS2_k127_1068351_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 603.0
TLS2_k127_1068351_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 438.0
TLS2_k127_1068351_2 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 368.0
TLS2_k127_1068351_3 PFAM Cytochrome c assembly protein K02195 - - 0.000000000000000000000000000000000000000000000004318 183.0
TLS2_k127_1068351_4 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000005698 175.0
TLS2_k127_1068351_5 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000002614 74.0
TLS2_k127_1069280_0 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 570.0
TLS2_k127_1069280_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 329.0
TLS2_k127_1069280_2 Trm112p-like protein - - - 0.00000000000000000001689 93.0
TLS2_k127_1069280_3 Ankyrin repeat - - - 0.00000000199 63.0
TLS2_k127_1070415_0 Ribosomal protein S1 K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 599.0
TLS2_k127_1070415_1 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 295.0
TLS2_k127_1070415_10 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000001515 66.0
TLS2_k127_1070415_2 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002155 255.0
TLS2_k127_1070415_3 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008919 241.0
TLS2_k127_1070415_4 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000000006817 231.0
TLS2_k127_1070415_5 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000745 199.0
TLS2_k127_1070415_6 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000001115 196.0
TLS2_k127_1070415_7 - - - - 0.0000000000000000000000000000000000000002967 154.0
TLS2_k127_1070415_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000003663 148.0
TLS2_k127_1070415_9 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000001961 103.0
TLS2_k127_107161_0 Ferrous iron transport protein B K04759 - - 5.459e-277 864.0
TLS2_k127_107161_1 ABC-type multidrug transport system ATPase component K01990 - - 7.752e-223 708.0
TLS2_k127_107161_10 FeoA K04758 - - 0.00000000000000000000005047 103.0
TLS2_k127_107161_11 PFAM MarR family - - - 0.000000000000000001306 92.0
TLS2_k127_107161_12 AAA domain K07028 - - 0.00000000000000002025 83.0
TLS2_k127_107161_13 mannitol 2-dehydrogenase activity - - - 0.000000002715 58.0
TLS2_k127_107161_2 peptidase dimerisation domain - - - 9.475e-195 618.0
TLS2_k127_107161_3 Sodium/hydrogen exchanger family K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 546.0
TLS2_k127_107161_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 471.0
TLS2_k127_107161_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 404.0
TLS2_k127_107161_6 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 321.0
TLS2_k127_107161_7 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006 295.0
TLS2_k127_107161_8 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005918 290.0
TLS2_k127_107161_9 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000001652 190.0
TLS2_k127_1078806_0 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 475.0
TLS2_k127_1078806_1 Putative adhesin - - - 0.000000000000000000000000000000000000000000000000000001279 205.0
TLS2_k127_1079240_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0 1035.0
TLS2_k127_1079240_1 Protein of unknown function (DUF1501) - - - 1.135e-211 672.0
TLS2_k127_1079240_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 464.0
TLS2_k127_1079838_0 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001185 253.0
TLS2_k127_1079838_1 FecR protein - - - 0.0000000000000000000000000000000000000000000000000001102 194.0
TLS2_k127_1080693_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 599.0
TLS2_k127_1080693_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 413.0
TLS2_k127_1080693_2 FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 332.0
TLS2_k127_1080693_3 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000004254 197.0
TLS2_k127_1080693_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000004936 179.0
TLS2_k127_1080693_5 TIGRFAM FeS assembly SUF system protein - - - 0.000000000000000000000000000000000003505 139.0
TLS2_k127_1080693_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000002188 102.0
TLS2_k127_1081297_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 527.0
TLS2_k127_1081297_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 461.0
TLS2_k127_1081297_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 361.0
TLS2_k127_1081297_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000001188 179.0
TLS2_k127_1090301_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 446.0
TLS2_k127_1090301_1 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 334.0
TLS2_k127_1090301_2 Protein of unknown function (DUF3592) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 313.0
TLS2_k127_1090301_4 CAAX protease self-immunity K07052,K09696 - - 0.0000000000000000000000000000003254 136.0
TLS2_k127_1090301_5 - - - - 0.000000000002353 69.0
TLS2_k127_1093806_0 Carboxypeptidase regulatory-like domain - - - 1.26e-213 704.0
TLS2_k127_1093806_1 FMN binding K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009887 281.0
TLS2_k127_1093806_2 FCD - - - 0.000000000000000000000000000000000000000000000000000000000004426 215.0
TLS2_k127_1093806_3 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000009704 168.0
TLS2_k127_1093806_4 KR domain - - - 0.00000000000000000000000000004168 120.0
TLS2_k127_1093806_5 Cytochrome c554 and c-prime - - - 0.0001261 51.0
TLS2_k127_1094531_0 PA domain - - - 1.02e-200 637.0
TLS2_k127_1094531_1 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 383.0
TLS2_k127_1094531_2 DinB family - - - 0.00000000000000000000000000000005457 132.0
TLS2_k127_1094531_3 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000646 104.0
TLS2_k127_1094531_4 Beta-lactamase superfamily domain - - - 0.0000000003003 71.0
TLS2_k127_1095254_0 Cytochrome c - - - 1.057e-199 653.0
TLS2_k127_1095254_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 531.0
TLS2_k127_1095254_2 hemerythrin HHE cation binding domain - - - 0.000000000000000000000001474 109.0
TLS2_k127_1104544_0 MacB-like periplasmic core domain - - - 1.5e-323 1013.0
TLS2_k127_1104544_1 FtsX-like permease family - - - 7.071e-213 690.0
TLS2_k127_1104544_2 AAA ATPase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 598.0
TLS2_k127_1104544_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 352.0
TLS2_k127_1104544_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001455 237.0
TLS2_k127_1104544_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000001577 235.0
TLS2_k127_1104544_6 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000001115 207.0
TLS2_k127_1104544_7 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000002247 183.0
TLS2_k127_1104544_8 transcriptional regulator PadR family - - - 0.0000000000000000000000000000000000000000000000002904 179.0
TLS2_k127_1104544_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000001075 169.0
TLS2_k127_1105028_0 Carbon starvation protein K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 370.0
TLS2_k127_1105028_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000008257 198.0
TLS2_k127_1118559_0 cell shape determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 599.0
TLS2_k127_1118559_1 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 497.0
TLS2_k127_1118559_2 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000002262 132.0
TLS2_k127_1147195_0 PFAM type II secretion system protein E K02283 - - 8.645e-207 652.0
TLS2_k127_1147195_1 type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 327.0
TLS2_k127_1147195_10 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.00000000000000000000000000000000000000000002646 176.0
TLS2_k127_1147195_11 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000001281 170.0
TLS2_k127_1147195_12 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000001045 123.0
TLS2_k127_1147195_13 Hfq protein - - - 0.000000000000000000000000003475 116.0
TLS2_k127_1147195_14 - - - - 0.0000000000002638 82.0
TLS2_k127_1147195_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 317.0
TLS2_k127_1147195_3 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 290.0
TLS2_k127_1147195_4 type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002469 287.0
TLS2_k127_1147195_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000001476 239.0
TLS2_k127_1147195_6 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000004576 237.0
TLS2_k127_1147195_7 Transcriptional regulator K13652 - - 0.00000000000000000000000000000000000000000000000000000000007986 216.0
TLS2_k127_1147195_8 PFAM SAF domain K02279 - - 0.000000000000000000000000000000000000000000000000000002522 201.0
TLS2_k127_1147195_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000002559 211.0
TLS2_k127_1148013_0 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 311.0
TLS2_k127_1148013_1 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004905 291.0
TLS2_k127_1148013_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000001427 138.0
TLS2_k127_1156953_0 COG2059 Chromate transport protein ChrA K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 354.0
TLS2_k127_1156953_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002047 270.0
TLS2_k127_1156953_2 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000001235 248.0
TLS2_k127_1160671_0 Cys/Met metabolism PLP-dependent enzyme K01042 - 2.9.1.1 7.384e-231 728.0
TLS2_k127_1160671_1 Tagatose 6 phosphate kinase K16371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 426.0
TLS2_k127_1160671_10 Domain of unknown function (DUF3368) - - - 0.00000000000000000000001459 106.0
TLS2_k127_1160671_11 Leucine-rich repeats, outliers - - - 0.00000000000000000000002599 112.0
TLS2_k127_1160671_12 Integrase catalytic - - - 0.00000000000000001088 88.0
TLS2_k127_1160671_2 PFAM Sugar isomerase (SIS) K02082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 397.0
TLS2_k127_1160671_3 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 343.0
TLS2_k127_1160671_4 DNA-binding transcription factor activity K02081,K02436,K02468,K03436 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 333.0
TLS2_k127_1160671_5 CBD_II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 339.0
TLS2_k127_1160671_6 Leucine-rich repeats, outliers - - - 0.0000000000000000000000000000000000000000000000000000000000000001539 245.0
TLS2_k127_1160671_7 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000002079 206.0
TLS2_k127_1160671_8 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000414 204.0
TLS2_k127_1160671_9 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000003553 153.0
TLS2_k127_116096_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 519.0
TLS2_k127_116096_1 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 355.0
TLS2_k127_116096_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000007654 171.0
TLS2_k127_116096_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000002241 126.0
TLS2_k127_1168519_0 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 457.0
TLS2_k127_1168519_1 enterobactin catabolic process K00700,K07214,K16147 - 2.4.1.18,2.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 366.0
TLS2_k127_1177042_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 413.0
TLS2_k127_1177042_1 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 332.0
TLS2_k127_1177042_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001652 260.0
TLS2_k127_1177042_3 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000003441 100.0
TLS2_k127_1179165_0 symporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009424 402.0
TLS2_k127_1179165_1 PFAM GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 393.0
TLS2_k127_1183795_0 - - - - 3.831e-270 842.0
TLS2_k127_1183795_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000006149 164.0
TLS2_k127_119025_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 500.0
TLS2_k127_119025_1 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 343.0
TLS2_k127_119025_2 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 307.0
TLS2_k127_1195677_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 323.0
TLS2_k127_1195677_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 293.0
TLS2_k127_1195677_2 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000166 187.0
TLS2_k127_1201094_0 PFAM penicillin-binding protein transpeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 329.0
TLS2_k127_1201094_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000001209 187.0
TLS2_k127_1201094_2 AntiSigma factor - - - 0.00000000000000008612 89.0
TLS2_k127_1214936_0 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 561.0
TLS2_k127_1214936_1 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 301.0
TLS2_k127_1214936_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004078 264.0
TLS2_k127_1214936_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000167 176.0
TLS2_k127_1257865_0 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 3.004e-219 691.0
TLS2_k127_1257865_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000004442 128.0
TLS2_k127_1257865_2 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.0000000000000000000000000001314 116.0
TLS2_k127_1259878_0 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 398.0
TLS2_k127_1259878_1 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000106 140.0
TLS2_k127_1259878_2 PFAM Colicin V production K03558 - - 0.00000000000000000895 92.0
TLS2_k127_1265485_0 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001231 261.0
TLS2_k127_1265485_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000003249 139.0
TLS2_k127_1265485_2 cellulose binding - - - 0.000000000000000008215 89.0
TLS2_k127_1271283_0 COGs COG4584 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000002418 249.0
TLS2_k127_1271283_1 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000008977 163.0
TLS2_k127_1271283_3 ParB-like nuclease domain K03497 - - 0.00000196 59.0
TLS2_k127_12876_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 308.0
TLS2_k127_12876_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 295.0
TLS2_k127_12876_2 Glycosyl transferase, family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001458 261.0
TLS2_k127_12876_3 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000001415 201.0
TLS2_k127_12876_4 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000001811 153.0
TLS2_k127_12876_5 Helix-turn-helix domain - - - 0.00000000000000000000000000000002614 130.0
TLS2_k127_12876_6 transport, permease protein K01992 - - 0.0000000000000000003611 96.0
TLS2_k127_12876_8 PFAM Glycosyl transferase, group 1 - - - 0.000000000295 70.0
TLS2_k127_1297498_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 403.0
TLS2_k127_1297498_1 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 298.0
TLS2_k127_1303463_0 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 599.0
TLS2_k127_1303463_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001548 242.0
TLS2_k127_1303463_2 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000000000003633 197.0
TLS2_k127_1303463_3 Transcriptional regulator PadR-like family K10947 - - 0.0000000000000000000000000000000000000000005677 162.0
TLS2_k127_1303463_5 TonB dependent receptor - - - 0.000000000000000000001536 96.0
TLS2_k127_1303463_6 efflux transmembrane transporter activity - - - 0.000000000000001696 78.0
TLS2_k127_1303463_7 UPF0060 membrane protein K09771 - - 0.00000000000005085 72.0
TLS2_k127_1303463_8 PFAM alpha beta hydrolase fold - - - 0.000000007808 61.0
TLS2_k127_1303463_9 - - - - 0.00001921 53.0
TLS2_k127_1305256_0 PFAM Xanthine uracil vitamin C permease K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 322.0
TLS2_k127_1305256_1 (ABC) transporter K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 299.0
TLS2_k127_1305256_2 PFAM Uncharacterised protein family UPF0150 K18843 - - 0.0000000000000000000000000000000000000000000000000000000000000000001653 232.0
TLS2_k127_1305256_3 - - - - 0.000000000000000009071 86.0
TLS2_k127_1305256_4 - - - - 0.00000000000141 72.0
TLS2_k127_1312412_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 506.0
TLS2_k127_1312412_1 phage Terminase large subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 395.0
TLS2_k127_1312412_2 - - - - 0.0000000000000000000000000000004966 129.0
TLS2_k127_1312412_3 P22 coat protein - gene protein 5 - - - 0.0000000000000000000000000000005811 124.0
TLS2_k127_1321191_0 PhoPQ-activated pathogenicity-related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 478.0
TLS2_k127_1321191_1 - - - - 0.000000000000000000000002779 107.0
TLS2_k127_1321191_2 efflux transmembrane transporter activity K15725 - - 0.00000000000003252 81.0
TLS2_k127_1330062_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 8.495e-197 624.0
TLS2_k127_1330062_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.219e-194 612.0
TLS2_k127_1330062_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 298.0
TLS2_k127_1330062_3 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
TLS2_k127_1330062_4 PFAM Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000005177 247.0
TLS2_k127_1330062_5 PFAM Chorismate mutase, type II - - - 0.00000000000000000004177 94.0
TLS2_k127_1330062_6 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000002591 97.0
TLS2_k127_1330062_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000004266 77.0
TLS2_k127_1332796_0 Aldehyde dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 597.0
TLS2_k127_1332796_1 Sigma-54 interaction domain K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 317.0
TLS2_k127_1332796_2 Cupin - - - 0.0000000000000000000000000000000000000008231 152.0
TLS2_k127_1332796_3 alcohol dehydrogenase K00055 - 1.1.1.90 0.00002691 50.0
TLS2_k127_136299_0 carboxylic acid catabolic process K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 304.0
TLS2_k127_136299_1 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01631,K01684 GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034192,GO:0034194,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.1.2.21,4.2.1.6 0.000000000000000000000000000000000000000000000003133 177.0
TLS2_k127_136299_2 protocatechuate 3,4-dioxygenase activity - - - 0.00001857 51.0
TLS2_k127_1378966_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1110.0
TLS2_k127_138145_0 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004484 252.0
TLS2_k127_138145_1 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000004692 134.0
TLS2_k127_1385723_0 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 448.0
TLS2_k127_1385723_1 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 359.0
TLS2_k127_1385723_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 316.0
TLS2_k127_1385723_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000003421 263.0
TLS2_k127_1385723_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000731 122.0
TLS2_k127_138954_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 372.0
TLS2_k127_138954_1 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000304 271.0
TLS2_k127_1391901_0 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 485.0
TLS2_k127_1391901_1 Ku70/Ku80 beta-barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 340.0
TLS2_k127_1391901_2 - K06862 - - 0.0000000000000000000000000000001068 124.0
TLS2_k127_1393373_0 PFAM type II secretion system protein E K02283 - - 2.448e-214 673.0
TLS2_k127_1393373_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 512.0
TLS2_k127_1393373_10 PFAM SAF domain K02279 - - 0.0000000000000000000000000000000000000000000000000000001922 204.0
TLS2_k127_1393373_12 Type IV leader peptidase family K02278 - 3.4.23.43 0.0000000000000000000000007226 111.0
TLS2_k127_1393373_13 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000004089 70.0
TLS2_k127_1393373_2 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 397.0
TLS2_k127_1393373_3 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 377.0
TLS2_k127_1393373_4 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 341.0
TLS2_k127_1393373_5 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 333.0
TLS2_k127_1393373_6 type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 318.0
TLS2_k127_1393373_7 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 314.0
TLS2_k127_1393373_8 type II secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 292.0
TLS2_k127_1393373_9 response regulator K02479,K07684,K07685 - - 0.00000000000000000000000000000000000000000000000000000000000000004776 229.0
TLS2_k127_1398454_0 protocatechuate 3,4-dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 573.0
TLS2_k127_1398454_1 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000009807 205.0
TLS2_k127_1398454_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000008398 148.0
TLS2_k127_1398454_3 Anti-sigma factor - - - 0.00000000000000000000000000000005987 142.0
TLS2_k127_1398454_4 region 4 type 2 K03088 - - 0.0000000000000000000000000001934 122.0
TLS2_k127_1398454_5 Beta-propeller repeat - - - 0.0000000000000000000000001238 121.0
TLS2_k127_1398454_6 pathogenesis K01337,K04565,K20276,K21449 - 1.15.1.1,3.4.21.50 0.000007497 58.0
TLS2_k127_1398915_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 445.0
TLS2_k127_1398915_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 418.0
TLS2_k127_1398915_2 nucleic acid binding K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 387.0
TLS2_k127_1398915_3 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 302.0
TLS2_k127_1398915_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000008852 228.0
TLS2_k127_1398915_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000000000000000000000003654 198.0
TLS2_k127_1398915_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000004855 124.0
TLS2_k127_1398915_7 PFAM Penicillinase repressor - - - 0.0000000000000000001443 93.0
TLS2_k127_1398915_8 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000004583 89.0
TLS2_k127_140152_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 357.0
TLS2_k127_140152_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005915 268.0
TLS2_k127_140152_2 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000000000004986 123.0
TLS2_k127_140152_3 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.0000008171 61.0
TLS2_k127_1403528_0 PFAM Cytochrome c assembly protein K02198 - - 3.451e-277 866.0
TLS2_k127_1403528_1 secreted protein-putative xanthan lyase related - - - 1.166e-252 792.0
TLS2_k127_1403528_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 572.0
TLS2_k127_1403528_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 381.0
TLS2_k127_1403528_4 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 303.0
TLS2_k127_1403528_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000006547 153.0
TLS2_k127_1403528_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000007176 148.0
TLS2_k127_1411348_0 Putative phage tail protein - - - 0.0 1244.0
TLS2_k127_1411348_1 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 460.0
TLS2_k127_1411348_10 DNA-binding transcription factor activity - - - 0.00000000000000000000000001201 112.0
TLS2_k127_1411348_11 Low molecular weight phosphatase family - - - 0.00000000000000000000000006323 114.0
TLS2_k127_1411348_12 - - - - 0.00000000000000000000006114 105.0
TLS2_k127_1411348_13 - - - - 0.000000000000000000000094 104.0
TLS2_k127_1411348_14 - - - - 0.000000000000001012 87.0
TLS2_k127_1411348_15 - - - - 0.000000000000006515 82.0
TLS2_k127_1411348_16 - - - - 0.00000000001237 72.0
TLS2_k127_1411348_2 P22 coat protein - gene protein 5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 423.0
TLS2_k127_1411348_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 384.0
TLS2_k127_1411348_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000001035 225.0
TLS2_k127_1411348_5 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000001143 206.0
TLS2_k127_1411348_6 - - - - 0.000000000000000000000000000000000000000000003926 173.0
TLS2_k127_1411348_7 - - - - 0.0000000000000000000000000000000000000000107 163.0
TLS2_k127_1411348_8 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000006326 154.0
TLS2_k127_1411348_9 Conserved hypothetical protein 2217 (DUF2460) - - - 0.000000000000000000000000007609 113.0
TLS2_k127_1421052_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000001292 89.0
TLS2_k127_1421052_1 Major Facilitator Superfamily - - - 0.000000000002791 74.0
TLS2_k127_142299_0 Surface antigen variable number - - - 4.28e-241 780.0
TLS2_k127_142299_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 574.0
TLS2_k127_142299_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 537.0
TLS2_k127_142299_3 MoeZ MoeB domain K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 441.0
TLS2_k127_142299_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000003683 228.0
TLS2_k127_142299_6 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000005352 129.0
TLS2_k127_142299_8 peptidyl-prolyl cis-trans isomerase activity K00645,K01802,K02597,K03769,K03770,K03771 - 2.3.1.39,5.2.1.8 0.000000000000000006533 95.0
TLS2_k127_142299_9 - - - - 0.00000000000000002147 84.0
TLS2_k127_1426972_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 397.0
TLS2_k127_1426972_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000003264 216.0
TLS2_k127_1430423_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 2.686e-280 867.0
TLS2_k127_1430423_1 G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 298.0
TLS2_k127_1430423_2 Belongs to the HpcH HpaI aldolase family - - - 0.0000000005498 63.0
TLS2_k127_1435280_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 6.547e-212 676.0
TLS2_k127_1435280_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 531.0
TLS2_k127_1435280_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000009009 170.0
TLS2_k127_1435280_11 - - - - 0.00000000000000000000000000000000000000000005043 165.0
TLS2_k127_1435280_12 Cytochrome P460 - - - 0.0000000000000000000000000000000000002378 147.0
TLS2_k127_1435280_13 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000005583 115.0
TLS2_k127_1435280_14 Pilus assembly protein CpaE K02282 - - 0.000000000000000004669 96.0
TLS2_k127_1435280_15 Helix-turn-helix XRE-family like proteins - - - 0.000000000006066 76.0
TLS2_k127_1435280_2 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 381.0
TLS2_k127_1435280_3 Aldose 1-epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 358.0
TLS2_k127_1435280_4 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 320.0
TLS2_k127_1435280_5 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 312.0
TLS2_k127_1435280_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004727 279.0
TLS2_k127_1435280_7 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000356 268.0
TLS2_k127_1435280_8 PFAM Appr-1-p processing - - - 0.00000000000000000000000000000000000000000000000001547 185.0
TLS2_k127_1435280_9 - - - - 0.000000000000000000000000000000000000000000000002062 180.0
TLS2_k127_1436369_0 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 452.0
TLS2_k127_1436369_1 PFAM Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 333.0
TLS2_k127_1436369_2 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 314.0
TLS2_k127_1436369_3 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000002383 213.0
TLS2_k127_145900_0 Bacterial cellulose synthase subunit K00694 - 2.4.1.12 1.023e-318 1025.0
TLS2_k127_145900_1 PFAM Cellulose synthase operon K20543 - - 5.973e-203 683.0
TLS2_k127_145900_2 PFAM glycoside hydrolase family 8 K20542 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 376.0
TLS2_k127_145900_3 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000000000003413 140.0
TLS2_k127_145900_4 aminopeptidase activity K19701 - 3.4.11.10,3.4.11.6 0.000000000000000000000000000004868 126.0
TLS2_k127_145900_5 cellulose synthase operon protein YhjQ - - - 0.0000000000000000000000481 113.0
TLS2_k127_1462516_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 433.0
TLS2_k127_1462516_1 COG2610 H gluconate symporter and related permeases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 413.0
TLS2_k127_1462516_2 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 299.0
TLS2_k127_1462516_3 MOSC domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001472 271.0
TLS2_k127_1462516_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000004748 245.0
TLS2_k127_1462516_5 - - - - 0.00000000000000002564 83.0
TLS2_k127_1462516_6 PFAM peptidase - - - 0.00003926 48.0
TLS2_k127_1485807_0 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 440.0
TLS2_k127_1485807_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 445.0
TLS2_k127_1485807_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000004771 216.0
TLS2_k127_1485807_3 - - - - 0.000000000000000000000000000004446 122.0
TLS2_k127_1485807_4 Tetratricopeptide repeat - - - 0.00000000000000001199 96.0
TLS2_k127_1489657_0 Cytochrome c - - - 0.0 1307.0
TLS2_k127_1489657_1 C-terminus of AA_permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 554.0
TLS2_k127_1489657_2 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 308.0
TLS2_k127_1489657_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000001451 159.0
TLS2_k127_150278_0 Prolyl oligopeptidase family - - - 3.71e-261 822.0
TLS2_k127_150278_1 Peptidase S46 - - - 2.307e-200 649.0
TLS2_k127_150278_10 PFAM S1 P1 nuclease - - - 0.0000000000000000000000000000000000000000000000000000009439 203.0
TLS2_k127_150278_11 DREV methyltransferase - - - 0.0000000000000000000000000000000000000000000006617 181.0
TLS2_k127_150278_12 transmembrane transport - - - 0.0000000000000000000000000000000000000000004707 162.0
TLS2_k127_150278_13 AAA domain - - - 0.000000000000000000000000000000000000000001145 163.0
TLS2_k127_150278_14 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000003399 147.0
TLS2_k127_150278_15 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000002004 149.0
TLS2_k127_150278_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.00000000000000000000000000000000003218 138.0
TLS2_k127_150278_17 molybdenum cofactor guanylyltransferase activity K03637,K03752,K13818 - 2.7.7.77,4.6.1.17 0.000000000000000000000006089 109.0
TLS2_k127_150278_18 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000006798 74.0
TLS2_k127_150278_19 Copper binding periplasmic protein CusF - - - 0.0000000000007269 76.0
TLS2_k127_150278_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 609.0
TLS2_k127_150278_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 382.0
TLS2_k127_150278_4 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002991 271.0
TLS2_k127_150278_5 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000003843 274.0
TLS2_k127_150278_6 Metal-binding integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007238 264.0
TLS2_k127_150278_7 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004062 243.0
TLS2_k127_150278_8 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000001283 243.0
TLS2_k127_150278_9 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002698 231.0
TLS2_k127_1504150_0 PFAM Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 443.0
TLS2_k127_1504150_1 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000003296 177.0
TLS2_k127_1513728_0 alpha-L-rhamnosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 577.0
TLS2_k127_1513728_1 PFAM M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 375.0
TLS2_k127_1513728_2 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 316.0
TLS2_k127_1513728_3 PFAM Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000006752 204.0
TLS2_k127_1513728_4 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000005986 136.0
TLS2_k127_1531959_0 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 595.0
TLS2_k127_1531959_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 560.0
TLS2_k127_1531959_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 540.0
TLS2_k127_1531959_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 452.0
TLS2_k127_1531959_4 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000000000003192 182.0
TLS2_k127_1531959_5 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000003263 104.0
TLS2_k127_1531959_6 Cytochrome c554 and c-prime K03620 - - 0.0001698 50.0
TLS2_k127_1540235_0 Peptidase M56 - - - 1.032e-198 634.0
TLS2_k127_1540235_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 431.0
TLS2_k127_1540235_2 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000000000002566 145.0
TLS2_k127_1540235_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000001227 101.0
TLS2_k127_1540235_4 - - - - 0.00000000000000000002348 95.0
TLS2_k127_1570684_0 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 308.0
TLS2_k127_1570684_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000001167 175.0
TLS2_k127_1570684_2 antisigma factor binding K04749 - - 0.000000000000000007118 87.0
TLS2_k127_1570684_3 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.00000000000000005141 86.0
TLS2_k127_1578058_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 616.0
TLS2_k127_1578058_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000615 178.0
TLS2_k127_1578058_2 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000002179 170.0
TLS2_k127_1578058_3 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000005843 154.0
TLS2_k127_1578058_4 COG1520 FOG WD40-like repeat - - - 0.0003982 46.0
TLS2_k127_157844_0 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 345.0
TLS2_k127_157844_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 301.0
TLS2_k127_157844_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003292 281.0
TLS2_k127_157844_3 SNARE associated Golgi protein - - - 0.00000000000000006608 91.0
TLS2_k127_1583147_0 Chase2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 447.0
TLS2_k127_1583147_1 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 301.0
TLS2_k127_1583147_2 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.000000000000000000000000000000000000000000000000000004823 201.0
TLS2_k127_1635779_0 carbohydrate binding K13688 - - 0.0 2479.0
TLS2_k127_1639555_0 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 368.0
TLS2_k127_164238_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.349e-200 634.0
TLS2_k127_164238_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 556.0
TLS2_k127_164238_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000448 264.0
TLS2_k127_164238_3 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 253.0
TLS2_k127_164238_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000004404 83.0
TLS2_k127_1674272_0 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 407.0
TLS2_k127_1674272_1 negative regulation of transcription, DNA-templated - - - 0.0000000000008812 69.0
TLS2_k127_1698146_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.487e-304 942.0
TLS2_k127_1698146_1 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000008905 235.0
TLS2_k127_1698146_2 PFAM SMP-30 Gluconolaconase - - - 0.00000004651 57.0
TLS2_k127_170580_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 316.0
TLS2_k127_170580_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 312.0
TLS2_k127_170580_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001023 293.0
TLS2_k127_170580_3 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001739 260.0
TLS2_k127_170580_4 response regulator receiver - - - 0.0000000000000000000000000000000000000000000003704 171.0
TLS2_k127_170580_5 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000003251 159.0
TLS2_k127_170580_6 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000127 150.0
TLS2_k127_170580_7 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000001592 158.0
TLS2_k127_170580_8 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000004859 126.0
TLS2_k127_170580_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000007049 104.0
TLS2_k127_172447_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 421.0
TLS2_k127_172447_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 335.0
TLS2_k127_172447_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000001186 226.0
TLS2_k127_172447_3 Domain of unknown function (DUF4870) - - - 0.00000000000000000000003389 106.0
TLS2_k127_1733485_0 class II (D K K01893 - 6.1.1.22 2.993e-201 633.0
TLS2_k127_1733485_1 PFAM Xylose isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 346.0
TLS2_k127_1733485_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005329 283.0
TLS2_k127_1780690_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.166e-206 656.0
TLS2_k127_1780690_1 efflux transmembrane transporter activity K02004 - - 1.795e-198 648.0
TLS2_k127_1780690_2 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 421.0
TLS2_k127_1780690_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000002535 228.0
TLS2_k127_1780690_4 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004545 226.0
TLS2_k127_1780690_5 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000001238 161.0
TLS2_k127_1780690_6 DNA Recombination protein RmuC K09760 GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000009087 134.0
TLS2_k127_1780690_7 phosphorelay signal transduction system - - - 0.00000000008905 68.0
TLS2_k127_1792468_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007701 268.0
TLS2_k127_1792468_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000123 254.0
TLS2_k127_1792468_2 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000000000006752 195.0
TLS2_k127_1792468_3 DREV methyltransferase - - - 0.0000000000000000000000000000000000000000000000285 177.0
TLS2_k127_1792468_4 Methyltransferase domain - - - 0.000000000000000000000000006666 112.0
TLS2_k127_180916_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 309.0
TLS2_k127_180916_1 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000001307 106.0
TLS2_k127_180916_2 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000002082 98.0
TLS2_k127_186127_0 Male sterility protein K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 319.0
TLS2_k127_186127_1 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002444 289.0
TLS2_k127_186127_2 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000004359 235.0
TLS2_k127_186127_3 protein kinase activity K13582,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000002507 236.0
TLS2_k127_186127_4 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000008961 222.0
TLS2_k127_1875076_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 509.0
TLS2_k127_1875076_1 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000002304 230.0
TLS2_k127_1877262_0 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 334.0
TLS2_k127_1877262_1 ABC transporter K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 294.0
TLS2_k127_1877262_2 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000003791 211.0
TLS2_k127_1881619_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000002763 93.0
TLS2_k127_1881848_0 Malate synthase K01638 - 2.3.3.9 7.661e-287 893.0
TLS2_k127_1881848_1 mandelate racemase muconate lactonizing K01684,K01781,K08323 - 4.2.1.6,4.2.1.8,5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 405.0
TLS2_k127_1881848_2 Glucose / Sorbosone dehydrogenase - - - 0.000008247 51.0
TLS2_k127_1881966_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000008305 59.0
TLS2_k127_1884316_0 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 503.0
TLS2_k127_1892324_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 307.0
TLS2_k127_1892324_1 peroxisomal (S)-2-hydroxy-acid oxidase K11517 GO:0003674,GO:0003824,GO:0003973,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0008150,GO:0008152,GO:0008891,GO:0009853,GO:0009987,GO:0010109,GO:0016032,GO:0016491,GO:0016614,GO:0016899,GO:0019048,GO:0019222,GO:0031323,GO:0035821,GO:0042579,GO:0043094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044003,GO:0044237,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051817,GO:0055114,GO:0065007 1.1.3.15 0.0000000000000000000000000000000000000000000003137 171.0
TLS2_k127_1892324_2 - - - - 0.000000000000000000000000000001885 136.0
TLS2_k127_1911861_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.95e-209 667.0
TLS2_k127_1911861_1 Domain of unknown function (DUF1835) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004486 250.0
TLS2_k127_1911861_2 glutamate-1-semialdehyde 2,1-aminomutase activity K01845 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000002032 219.0
TLS2_k127_1911861_3 DNA-templated transcription, initiation - - - 0.0000001251 60.0
TLS2_k127_1916626_0 Cytochrome c - - - 7.599e-241 775.0
TLS2_k127_1916626_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000569 259.0
TLS2_k127_1916626_2 PFAM Peptidase M20 K01436 - - 0.00000000000000000000007265 103.0
TLS2_k127_1925012_0 Domain of unknown function (DUF1998) K06877 - - 3.486e-267 832.0
TLS2_k127_1925012_1 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 442.0
TLS2_k127_1925012_2 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.0000000000000000000000000000000000000000000000000000000000004357 216.0
TLS2_k127_1925012_3 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.00000000000000000000000000000000000000002467 169.0
TLS2_k127_1925012_4 - - - - 0.0000000000000000000000013 107.0
TLS2_k127_1925012_5 Phosphopantetheine attachment site - - - 0.00000000000000002345 85.0
TLS2_k127_1926307_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 473.0
TLS2_k127_1926307_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00006409 51.0
TLS2_k127_1929916_0 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 560.0
TLS2_k127_1929916_1 Glucose uptake K05340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 450.0
TLS2_k127_1929916_2 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 419.0
TLS2_k127_1929916_3 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 398.0
TLS2_k127_1929916_4 purine nucleotide biosynthetic process K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 384.0
TLS2_k127_1929916_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 300.0
TLS2_k127_1929916_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000002739 243.0
TLS2_k127_193002_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.392e-205 655.0
TLS2_k127_193002_1 L-seryl-tRNASec selenium transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 427.0
TLS2_k127_193002_2 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000006794 208.0
TLS2_k127_193002_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000000000001192 189.0
TLS2_k127_193002_4 L-lactate permease K03303 - - 0.00000000000000000000000000000000000001648 147.0
TLS2_k127_1933655_0 Belongs to the peptidase S8 family K12287 - - 0.0000000000000000000000000000000000000001158 168.0
TLS2_k127_1933655_1 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K07404 - 3.1.1.31 0.000000000000000000000000001198 118.0
TLS2_k127_1933719_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 569.0
TLS2_k127_1933719_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000403 139.0
TLS2_k127_1933719_2 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000001395 112.0
TLS2_k127_1933834_0 efflux protein, MATE family K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 459.0
TLS2_k127_1933834_1 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 346.0
TLS2_k127_1933834_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000005669 117.0
TLS2_k127_1947384_0 efflux transmembrane transporter activity - - - 0.0 1086.0
TLS2_k127_1947384_1 FtsX-like permease family - - - 0.0 1067.0
TLS2_k127_1947384_2 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000000000000000000004681 200.0
TLS2_k127_1948965_0 dehydrogenase e1 component K00164 - 1.2.4.2 5.941e-248 775.0
TLS2_k127_1952025_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 572.0
TLS2_k127_1952025_1 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.000000000000000000000000000000000000000002669 160.0
TLS2_k127_1952025_2 Heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000033 132.0
TLS2_k127_1953891_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 458.0
TLS2_k127_1953891_1 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000003095 150.0
TLS2_k127_1953891_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000003836 67.0
TLS2_k127_1956043_0 Belongs to the BshC family K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 484.0
TLS2_k127_1956043_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.000000000000000000000000000000000000000000000000000007593 192.0
TLS2_k127_1956043_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000001055 170.0
TLS2_k127_1956043_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000005601 160.0
TLS2_k127_1958928_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000006187 166.0
TLS2_k127_1958928_1 Tetratricopeptide repeat - - - 0.00000001189 67.0
TLS2_k127_196175_0 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 577.0
TLS2_k127_196175_1 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 285.0
TLS2_k127_196175_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001843 222.0
TLS2_k127_196175_3 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000004864 202.0
TLS2_k127_196175_4 addiction module antidote protein HigA K21498 - - 0.0000000000000000000000000000000000000000000000000004814 187.0
TLS2_k127_196175_5 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000002269 178.0
TLS2_k127_196175_6 PFAM Plasmid maintenance system killer K07334 - - 0.000000000000000000000000000000000000000000009564 164.0
TLS2_k127_196175_7 RibD C-terminal domain - - - 0.0000000000000000000000000008118 112.0
TLS2_k127_196175_8 - - - - 0.00000000000000000004362 93.0
TLS2_k127_1962382_0 domain protein - - - 2.45e-270 864.0
TLS2_k127_1962382_1 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 385.0
TLS2_k127_1963597_0 PFAM 4Fe-4S binding domain - - - 1.943e-207 654.0
TLS2_k127_1963597_1 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 324.0
TLS2_k127_1963597_2 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000000000000006149 195.0
TLS2_k127_1963597_3 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000002598 148.0
TLS2_k127_1963597_4 Thioesterase superfamily - - - 0.00000000000000000000000000006554 121.0
TLS2_k127_1963812_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 546.0
TLS2_k127_1963812_1 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 318.0
TLS2_k127_1963812_2 eRF1 domain 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 304.0
TLS2_k127_1963812_3 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000105 230.0
TLS2_k127_1967873_0 Dehydrogenase E1 component K11381 - 1.2.4.4 3.452e-234 742.0
TLS2_k127_1967873_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 541.0
TLS2_k127_1967873_2 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 439.0
TLS2_k127_1967873_3 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 365.0
TLS2_k127_1967873_4 hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000134 277.0
TLS2_k127_1967873_5 Ferredoxin K02230 - 6.6.1.2 0.000000000000000000000000000000000000003128 155.0
TLS2_k127_1967873_6 PFAM response regulator receiver - - - 0.0000000000000000000000000005946 119.0
TLS2_k127_1967873_7 Uncharacterized ACR, COG1430 - - - 0.00000000000000000000000001229 121.0
TLS2_k127_1967873_8 Transcriptional regulator PadR-like family - - - 0.00000000000000000002986 95.0
TLS2_k127_1968933_0 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000006685 169.0
TLS2_k127_1968933_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000223 131.0
TLS2_k127_1972731_0 DNA topological change K03168 - 5.99.1.2 9.162e-291 916.0
TLS2_k127_1972731_1 DNA topological change K03168 - 5.99.1.2 3.413e-238 763.0
TLS2_k127_1972731_10 Proline racemase K12658 - 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 437.0
TLS2_k127_1972731_11 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 430.0
TLS2_k127_1972731_12 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 422.0
TLS2_k127_1972731_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 376.0
TLS2_k127_1972731_14 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 358.0
TLS2_k127_1972731_15 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 323.0
TLS2_k127_1972731_16 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000001292 177.0
TLS2_k127_1972731_18 PIN domain - - - 0.0000000000000000000001184 104.0
TLS2_k127_1972731_19 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000002499 93.0
TLS2_k127_1972731_2 Protein of unknown function (DUF1552) - - - 2.562e-198 627.0
TLS2_k127_1972731_20 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000001933 93.0
TLS2_k127_1972731_21 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000003335 91.0
TLS2_k127_1972731_3 Sodium:neurotransmitter symporter family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 610.0
TLS2_k127_1972731_4 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 587.0
TLS2_k127_1972731_5 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 506.0
TLS2_k127_1972731_6 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 510.0
TLS2_k127_1972731_7 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 475.0
TLS2_k127_1972731_8 Belongs to the DapA family K01714,K21062 - 3.5.4.22,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 449.0
TLS2_k127_1972731_9 TIM-barrel enzyme, possibly a dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 434.0
TLS2_k127_1980832_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 6.735e-306 951.0
TLS2_k127_1980832_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000242 237.0
TLS2_k127_1980832_2 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000016 82.0
TLS2_k127_1981764_0 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 494.0
TLS2_k127_1981764_1 domain, Protein K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 494.0
TLS2_k127_1981764_2 Histidine kinase - - - 0.0000000000000000000000000000002158 126.0
TLS2_k127_1987959_0 dead deah K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 443.0
TLS2_k127_1987959_1 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 342.0
TLS2_k127_1987959_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000009968 193.0
TLS2_k127_1987959_3 oxidoreductase activity K12511 - - 0.0000000000000000000000005782 120.0
TLS2_k127_1987959_4 Membrane - - - 0.00001194 56.0
TLS2_k127_200166_0 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 3.591e-252 803.0
TLS2_k127_200166_1 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001914 266.0
TLS2_k127_2010268_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000001947 237.0
TLS2_k127_2010268_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000254 140.0
TLS2_k127_2010268_2 Lytic transglycosylase catalytic K08307 - - 0.0000000001054 74.0
TLS2_k127_2010268_3 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00000006659 65.0
TLS2_k127_2010462_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 325.0
TLS2_k127_2010462_1 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000000000000000000002687 176.0
TLS2_k127_2010687_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000006655 237.0
TLS2_k127_2010687_1 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000000003948 220.0
TLS2_k127_2010687_2 Beta-propeller repeat - - - 0.000000000000000000000000000000000000002906 166.0
TLS2_k127_2015213_0 transport - - - 3.427e-289 925.0
TLS2_k127_2015213_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 8.388e-225 702.0
TLS2_k127_2015213_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 363.0
TLS2_k127_2015213_3 metallophosphoesterase K07096,K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001785 249.0
TLS2_k127_2015213_4 addiction module antidote protein, CC2985 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002857 256.0
TLS2_k127_2015213_5 - - - - 0.00000000000000000000001989 102.0
TLS2_k127_2015213_6 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000004171 72.0
TLS2_k127_2015213_7 PBS lyase HEAT-like repeat - - - 0.000000001432 70.0
TLS2_k127_2015213_8 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.00000001776 67.0
TLS2_k127_2038104_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2321.0
TLS2_k127_2038104_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2257.0
TLS2_k127_2038104_10 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000001255 130.0
TLS2_k127_2038104_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000005641 71.0
TLS2_k127_2038104_12 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000001039 68.0
TLS2_k127_2038104_13 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000002319 65.0
TLS2_k127_2038104_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 562.0
TLS2_k127_2038104_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 518.0
TLS2_k127_2038104_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 343.0
TLS2_k127_2038104_5 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 296.0
TLS2_k127_2038104_6 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 289.0
TLS2_k127_2038104_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000009652 206.0
TLS2_k127_2038104_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000005325 201.0
TLS2_k127_2038104_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000001534 182.0
TLS2_k127_2040952_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1114.0
TLS2_k127_2040952_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 475.0
TLS2_k127_2040952_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 439.0
TLS2_k127_2040952_3 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 398.0
TLS2_k127_2040952_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 321.0
TLS2_k127_2040952_5 periplasmic or secreted lipoprotein K07339 - - 0.0001414 46.0
TLS2_k127_2043227_0 PFAM Alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 574.0
TLS2_k127_2043227_1 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 387.0
TLS2_k127_2043227_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 310.0
TLS2_k127_2043227_3 Phospholipase D Transphosphatidylase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001399 282.0
TLS2_k127_2043227_4 6-phospho-beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001539 262.0
TLS2_k127_2043227_5 - - - - 0.0000000000000000000000000000000000000187 155.0
TLS2_k127_2043227_6 Domain of unknown function (DUF892) - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000005244 81.0
TLS2_k127_2043227_7 Uncharacterized conserved protein (COG2071) K09166 - - 0.000000000003312 67.0
TLS2_k127_2045867_0 Protein of unknown function (DUF1549) - - - 0.0 1009.0
TLS2_k127_2045867_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 406.0
TLS2_k127_2046301_0 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001562 252.0
TLS2_k127_2046301_1 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000000000000000000000000000000000000000000000000000000294 202.0
TLS2_k127_2046301_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000009099 74.0
TLS2_k127_2050000_0 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 385.0
TLS2_k127_2058290_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000739 218.0
TLS2_k127_2058290_1 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000005758 203.0
TLS2_k127_2058290_2 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000000000000000000000000007524 161.0
TLS2_k127_2058290_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000008941 130.0
TLS2_k127_2058290_4 arylsulfatase activity - - - 0.00001321 49.0
TLS2_k127_2059416_0 Transketolase, pyrimidine binding domain K00161,K00162,K00167,K11381 - 1.2.4.1,1.2.4.4 0.0 1062.0
TLS2_k127_2059416_1 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000008395 151.0
TLS2_k127_2059416_2 YCII-related domain - - - 0.00000000000000000000015 98.0
TLS2_k127_2059566_0 efflux transmembrane transporter activity - - - 0.0 1026.0
TLS2_k127_2059566_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000001025 174.0
TLS2_k127_2060745_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 333.0
TLS2_k127_2060745_1 gluconolactonase activity K14274,K20274 - - 0.000000000000000000000000000000000000000000000257 181.0
TLS2_k127_2065547_0 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 374.0
TLS2_k127_2065547_1 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 376.0
TLS2_k127_2065547_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 307.0
TLS2_k127_2073547_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.578e-263 823.0
TLS2_k127_2073547_1 PFAM von Willebrand factor type A K07114,K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 340.0
TLS2_k127_2073547_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 310.0
TLS2_k127_2073547_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001545 252.0
TLS2_k127_2073547_4 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000001094 196.0
TLS2_k127_2073547_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000001118 135.0
TLS2_k127_2073547_7 hyperosmotic response - - - 0.00000000000000000000000000006829 124.0
TLS2_k127_2073547_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000001867 102.0
TLS2_k127_2073547_9 - - - - 0.0000000000000002142 79.0
TLS2_k127_2078118_0 FtsX-like permease family K02004 - - 2.234e-194 621.0
TLS2_k127_2078118_1 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000001193 223.0
TLS2_k127_2078654_0 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 422.0
TLS2_k127_2084391_0 amine dehydrogenase activity K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001461 268.0
TLS2_k127_2084391_1 peptidyl-tyrosine sulfation - - - 0.00001161 56.0
TLS2_k127_208532_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 3.674e-212 668.0
TLS2_k127_208532_1 synthase K01719,K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 567.0
TLS2_k127_208532_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 474.0
TLS2_k127_208532_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 310.0
TLS2_k127_208532_4 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000441 276.0
TLS2_k127_208532_5 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000954 272.0
TLS2_k127_2087633_2 TadE-like protein - - - 0.0000004369 60.0
TLS2_k127_2092891_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 467.0
TLS2_k127_2092891_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 377.0
TLS2_k127_2092891_2 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 338.0
TLS2_k127_2092891_3 Demethylmenaquinone methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 293.0
TLS2_k127_2092891_4 phosphinothricin N-acetyltransferase activity K03825 - - 0.000000000000000000000000006118 112.0
TLS2_k127_2092891_5 Cold shock protein domain K03704 - - 0.0000000000001253 70.0
TLS2_k127_2097916_0 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 459.0
TLS2_k127_2097916_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 304.0
TLS2_k127_2097916_2 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000005455 259.0
TLS2_k127_2097916_3 von Willebrand factor, type A K07114 - - 0.0000000000001424 80.0
TLS2_k127_2121186_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 448.0
TLS2_k127_2121186_1 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000005919 153.0
TLS2_k127_2121186_2 Tetratricopeptide repeat - - - 0.0000000009743 61.0
TLS2_k127_2123832_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 673.0
TLS2_k127_2123832_1 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000004005 197.0
TLS2_k127_2123832_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000009732 74.0
TLS2_k127_2123832_3 transcriptional regulator K07726 - - 0.000000000001218 77.0
TLS2_k127_2123832_4 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000001012 54.0
TLS2_k127_2123832_5 endoribonuclease activity - GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0031974,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 - 0.00001344 57.0
TLS2_k127_2135637_0 extracellular polysaccharide biosynthetic process K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 356.0
TLS2_k127_2135637_1 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 319.0
TLS2_k127_2135637_2 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005256 265.0
TLS2_k127_2135637_3 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004674 237.0
TLS2_k127_2135637_4 protein tyrosine kinase activity - - - 0.0000000000000000000000000000000000000000000000000003284 209.0
TLS2_k127_2135637_5 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000001155 196.0
TLS2_k127_2135637_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000006182 175.0
TLS2_k127_2135637_7 AAA domain K02450 - - 0.0000000000000000000000000000000000000006571 170.0
TLS2_k127_2135637_8 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000001533 126.0
TLS2_k127_2135637_9 Polymerase - - - 0.0000000000001326 83.0
TLS2_k127_2139584_0 MacB-like periplasmic core domain - - - 1.401e-240 773.0
TLS2_k127_2139584_1 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 380.0
TLS2_k127_2139584_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 386.0
TLS2_k127_2139584_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000001423 230.0
TLS2_k127_2139584_4 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000003706 166.0
TLS2_k127_2151064_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 466.0
TLS2_k127_2151064_1 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 338.0
TLS2_k127_2154190_0 Aminotransferase class-III - - - 3.654e-210 661.0
TLS2_k127_2154190_1 CBD_II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 336.0
TLS2_k127_2154190_2 Transcriptional regulator K03710,K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009062 269.0
TLS2_k127_2154190_3 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000003886 251.0
TLS2_k127_2154190_4 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000008496 210.0
TLS2_k127_2157231_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 546.0
TLS2_k127_2157231_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 550.0
TLS2_k127_2157231_2 PFAM AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 491.0
TLS2_k127_2157231_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 480.0
TLS2_k127_2157231_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 441.0
TLS2_k127_2157231_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K01710,K02377 - 1.1.1.271,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 346.0
TLS2_k127_2157231_6 PFAM Acetamidase Formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 315.0
TLS2_k127_2159153_0 lipopolysaccharide transport K22110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 332.0
TLS2_k127_2159153_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 308.0
TLS2_k127_2159153_2 PFAM Stage II sporulation E family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003034 260.0
TLS2_k127_2159153_3 - - - - 0.000000000000000000000000000000000000000000000000000006322 199.0
TLS2_k127_2162310_0 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000001985 262.0
TLS2_k127_2162310_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000004329 144.0
TLS2_k127_2162310_2 - - - - 0.00000000000000001518 83.0
TLS2_k127_2162310_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634,K14166 - - 0.00000000000002418 80.0
TLS2_k127_2162310_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000008711 66.0
TLS2_k127_2162310_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00001183 49.0
TLS2_k127_2162932_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 337.0
TLS2_k127_2162932_1 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 314.0
TLS2_k127_2162932_2 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 293.0
TLS2_k127_2162932_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000003076 181.0
TLS2_k127_2162932_4 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000003302 53.0
TLS2_k127_216375_0 Dehydrogenase K00117 - 1.1.5.2 0.0 1010.0
TLS2_k127_216375_1 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 490.0
TLS2_k127_216375_10 nucleotidyltransferase activity K07075 - - 0.00003428 49.0
TLS2_k127_216375_2 Elongator protein 3, MiaB family, Radical SAM K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 359.0
TLS2_k127_216375_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000003262 199.0
TLS2_k127_216375_4 amine dehydrogenase activity K12287 - - 0.00000000000000000000000000000000000000000000001302 192.0
TLS2_k127_216375_5 Cupin domain - - - 0.0000000000000000000000000000000000003437 152.0
TLS2_k127_216375_6 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.000000000000000000000005328 106.0
TLS2_k127_216375_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000001839 92.0
TLS2_k127_216375_8 - - - - 0.0000000001332 66.0
TLS2_k127_216375_9 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000003376 70.0
TLS2_k127_216806_0 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002817 296.0
TLS2_k127_216806_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000002036 93.0
TLS2_k127_216806_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000001153 81.0
TLS2_k127_216806_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11959 - - 0.000003966 57.0
TLS2_k127_2168140_0 C-terminus of AA_permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 550.0
TLS2_k127_2168140_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 346.0
TLS2_k127_2168140_2 Phage integrase family - - - 0.00000000000000000000000000000000000000000000006058 176.0
TLS2_k127_2168140_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000001819 159.0
TLS2_k127_2168140_4 OsmC-like protein - - - 0.0000000000000000000000000000002338 125.0
TLS2_k127_2168140_5 Rhodanese Homology Domain K00529 - 1.18.1.3 0.000000000000000000000001323 104.0
TLS2_k127_2173523_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 1.271e-225 741.0
TLS2_k127_2173523_1 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.000000000000000000000000000000000000000000000005083 179.0
TLS2_k127_2178011_0 PFAM Transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 419.0
TLS2_k127_2178011_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 351.0
TLS2_k127_2178011_2 PFAM bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 288.0
TLS2_k127_2178011_3 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006323 279.0
TLS2_k127_2178011_4 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006038 268.0
TLS2_k127_2178011_5 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000006086 245.0
TLS2_k127_2178011_6 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000000000000000000005165 207.0
TLS2_k127_2178011_7 - - - - 0.000000000000000000000000003736 115.0
TLS2_k127_2178011_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000002979 114.0
TLS2_k127_2178011_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00002848 49.0
TLS2_k127_2199925_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 455.0
TLS2_k127_2199925_1 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 327.0
TLS2_k127_2199925_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000001495 145.0
TLS2_k127_2199925_3 addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000000000000000008188 135.0
TLS2_k127_2207415_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.909e-296 918.0
TLS2_k127_2207415_1 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002238 233.0
TLS2_k127_2207415_2 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000001862 228.0
TLS2_k127_2207415_3 YCII-related domain - - - 0.0000000000000000003271 89.0
TLS2_k127_2207415_4 Transcriptional regulatory protein, C terminal - - - 0.000001335 53.0
TLS2_k127_2217385_1 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 355.0
TLS2_k127_2217385_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001568 228.0
TLS2_k127_2217385_3 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000005308 226.0
TLS2_k127_2217385_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000001046 150.0
TLS2_k127_2217385_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000007943 48.0
TLS2_k127_221952_0 alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 5.685e-249 778.0
TLS2_k127_221952_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 302.0
TLS2_k127_2222816_0 Ferrous iron transport protein B C terminus K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 612.0
TLS2_k127_2222816_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 492.0
TLS2_k127_2222816_2 Ferrous iron transport protein B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 351.0
TLS2_k127_2222816_3 iron ion homeostasis K03322,K03709,K04758 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 352.0
TLS2_k127_2222816_4 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 372.0
TLS2_k127_2222816_5 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.00000000000000000000000000000000000000000000000000000000000002176 222.0
TLS2_k127_2222816_6 - - - - 0.000000000000000000000000000000001157 139.0
TLS2_k127_2222816_7 cell adhesion involved in biofilm formation K01186 - 3.2.1.18 0.00000000000000000000003322 117.0
TLS2_k127_2222816_8 PFAM Glycosyl transferases group 1 - - - 0.00000001766 57.0
TLS2_k127_2223515_0 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 486.0
TLS2_k127_2226859_0 Cytochrome c - - - 1.368e-224 713.0
TLS2_k127_2232914_0 Cobalt ABC transporter K02008 - - 0.00000000000000000000000000000009528 134.0
TLS2_k127_2232914_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000003698 73.0
TLS2_k127_2232914_2 Surface antigen - - - 0.000000003644 68.0
TLS2_k127_2232914_3 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.000004234 51.0
TLS2_k127_2239774_0 AcrB/AcrD/AcrF family K15726 - - 1.096e-240 769.0
TLS2_k127_2239774_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001321 235.0
TLS2_k127_2239774_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15727 - - 0.00000000000000000000000000000000000000000000000000005995 203.0
TLS2_k127_2262366_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005753 264.0
TLS2_k127_2262366_1 Surface antigen - - - 0.0000000000000000000003682 110.0
TLS2_k127_2262366_2 amino acid - - - 0.0000000000000000001294 88.0
TLS2_k127_2262366_3 TIR domain - - - 0.000000000000000004176 92.0
TLS2_k127_226282_0 Flagellar basal body protein FlaE K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 364.0
TLS2_k127_226282_1 FlhB HrpN YscU SpaS Family K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 323.0
TLS2_k127_226282_10 Flagellar biosynthesis protein, FliO K02418 - - 0.0005938 46.0
TLS2_k127_226282_2 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 317.0
TLS2_k127_226282_3 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 305.0
TLS2_k127_226282_4 PFAM OmpA K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000001087 242.0
TLS2_k127_226282_5 Bacterial export proteins, family 1 K02421 - - 0.0000000000000000000000000000000000000006157 158.0
TLS2_k127_226282_6 Bacterial export proteins, family 3 K02420 - - 0.00000000000000000000005389 100.0
TLS2_k127_226282_7 PFAM flagellar FlbD family protein K02385 - - 0.0000000000000000169 87.0
TLS2_k127_226282_8 Required for flagellar hook formation. May act as a scaffolding protein K02389 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.000000000000009918 79.0
TLS2_k127_226282_9 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.00001748 50.0
TLS2_k127_2271169_0 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 518.0
TLS2_k127_2271169_1 Membrane-bound dehydrogenase domain - - - 0.0000000003141 66.0
TLS2_k127_2285115_0 sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 610.0
TLS2_k127_2285115_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 526.0
TLS2_k127_2285115_2 Hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 321.0
TLS2_k127_2285115_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 287.0
TLS2_k127_2285115_4 - - - - 0.000000000000000008678 93.0
TLS2_k127_2294945_0 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 328.0
TLS2_k127_2294945_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 291.0
TLS2_k127_2294945_2 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001645 274.0
TLS2_k127_2322827_0 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000004473 265.0
TLS2_k127_2322827_1 - K07018 - - 0.0000000000000000000001529 102.0
TLS2_k127_2324008_0 RNA polymerase sigma-54 factor K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 520.0
TLS2_k127_2324008_1 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 359.0
TLS2_k127_2324008_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 361.0
TLS2_k127_2324008_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.000000000000000000000000000000000008201 149.0
TLS2_k127_2324008_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000189 70.0
TLS2_k127_2333941_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.105e-299 936.0
TLS2_k127_2333941_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 404.0
TLS2_k127_2333941_2 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 361.0
TLS2_k127_2333941_3 TIGRFAM TonB family K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000283 234.0
TLS2_k127_2333941_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000008921 233.0
TLS2_k127_2333941_5 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000276 173.0
TLS2_k127_2333941_6 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000006409 161.0
TLS2_k127_2350307_0 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 352.0
TLS2_k127_2350307_1 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007582 277.0
TLS2_k127_2350307_2 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 255.0
TLS2_k127_2350307_3 amine dehydrogenase activity K12287 - - 0.0000000000000000000000000000000000000000000000000000000000000001807 234.0
TLS2_k127_2350307_4 Cupin domain - - - 0.000000000000000000000000000000000008333 139.0
TLS2_k127_2352890_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 572.0
TLS2_k127_2382282_0 peptidyl-tyrosine sulfation - - - 2.207e-219 707.0
TLS2_k127_2382282_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 642.0
TLS2_k127_2382282_2 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 315.0
TLS2_k127_2382282_3 Bacterial transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000004894 239.0
TLS2_k127_2382282_4 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000007748 174.0
TLS2_k127_2382282_5 F-box LRR-repeat protein - - - 0.00000000000000000000000000000000000000000000001277 194.0
TLS2_k127_2382282_6 AraC family transcriptional regulator - - - 0.00000000000000000000000003525 120.0
TLS2_k127_2382282_7 regulation of response to stimulus K13730 - - 0.00000000004086 75.0
TLS2_k127_2382282_8 Tetratricopeptide repeat - - - 0.00001743 58.0
TLS2_k127_2386479_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 558.0
TLS2_k127_2386479_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 489.0
TLS2_k127_2386479_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 449.0
TLS2_k127_2386479_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 368.0
TLS2_k127_2386479_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 321.0
TLS2_k127_2386479_5 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000268 103.0
TLS2_k127_239165_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 577.0
TLS2_k127_239165_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 563.0
TLS2_k127_239165_2 Methyl-transferase K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 373.0
TLS2_k127_239165_3 gluconolactonase activity K01053 GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 360.0
TLS2_k127_239165_4 macromolecule localization K01992,K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001563 276.0
TLS2_k127_239165_5 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003434 255.0
TLS2_k127_239165_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000333 218.0
TLS2_k127_239165_7 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000001575 124.0
TLS2_k127_239165_8 CAAX protease self-immunity - - - 0.000000000000000000000000114 119.0
TLS2_k127_239165_9 - - - - 0.000000000000000000006787 98.0
TLS2_k127_2409323_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.283e-232 744.0
TLS2_k127_2409323_1 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 618.0
TLS2_k127_2409323_2 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000004415 177.0
TLS2_k127_2409323_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000005764 156.0
TLS2_k127_2409323_4 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.000000000000000000000000001407 117.0
TLS2_k127_2409323_6 - - - - 0.0000000000002571 79.0
TLS2_k127_2409323_7 SnoaL-like domain - - - 0.0000000000007863 71.0
TLS2_k127_243485_0 Glycosyl transferases group 1 - - - 1.928e-269 853.0
TLS2_k127_243485_1 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000000000000000000000000000000000005692 211.0
TLS2_k127_243485_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000002606 96.0
TLS2_k127_2444375_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 318.0
TLS2_k127_2444375_1 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000001102 65.0
TLS2_k127_2452249_0 cellulose binding - - - 0.0000000000000000000000000000000000000002723 160.0
TLS2_k127_2452249_1 diguanylate cyclase - - - 0.00000000000000001282 90.0
TLS2_k127_246725_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 538.0
TLS2_k127_246725_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 485.0
TLS2_k127_246725_2 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 487.0
TLS2_k127_246725_3 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 478.0
TLS2_k127_246725_4 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006951 274.0
TLS2_k127_2477510_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 378.0
TLS2_k127_2477510_1 CoA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002297 271.0
TLS2_k127_2477510_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003764 249.0
TLS2_k127_2479429_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 470.0
TLS2_k127_2479429_1 Domain of unknown function (DUF1972) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 443.0
TLS2_k127_2479429_2 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005013 271.0
TLS2_k127_2479429_3 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007357 249.0
TLS2_k127_2479429_4 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000002323 237.0
TLS2_k127_2479429_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000002203 138.0
TLS2_k127_2479429_6 Transposase - - - 0.00000000004596 70.0
TLS2_k127_2479429_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0001659 51.0
TLS2_k127_249861_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 329.0
TLS2_k127_249861_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 320.0
TLS2_k127_249861_2 Cellulase (Glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000003347 261.0
TLS2_k127_249861_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000007192 132.0
TLS2_k127_249861_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000006204 116.0
TLS2_k127_249861_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000002302 76.0
TLS2_k127_2551628_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.919e-257 797.0
TLS2_k127_2551628_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 330.0
TLS2_k127_2551628_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000001495 248.0
TLS2_k127_2551628_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000002373 182.0
TLS2_k127_2551628_4 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.000000000000000000000000000001538 124.0
TLS2_k127_2563397_0 Carboxypeptidase regulatory-like domain - - - 1.742e-220 713.0
TLS2_k127_2563397_1 FCD - - - 0.000000000000000000000000000000000000000001317 165.0
TLS2_k127_2575306_0 Dienelactone hydrolase and related enzymes K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 420.0
TLS2_k127_2575306_1 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000009828 224.0
TLS2_k127_2575306_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0004604 43.0
TLS2_k127_2586531_0 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 463.0
TLS2_k127_2586531_1 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000577 274.0
TLS2_k127_2586531_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000005483 181.0
TLS2_k127_2586531_3 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000006374 179.0
TLS2_k127_2586531_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000006819 75.0
TLS2_k127_2603469_0 CBD_II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 354.0
TLS2_k127_2603469_1 Protein of unknown function (DUF1552) - - - 0.00000000000008561 79.0
TLS2_k127_2613105_0 - - - - 0.00000000000000000000000000000000000000000000000000000002518 209.0
TLS2_k127_2613105_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000001513 106.0
TLS2_k127_2616026_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 7.719e-264 831.0
TLS2_k127_2616026_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 368.0
TLS2_k127_2616026_2 transcriptional regulator, PadR family - - - 0.000000000000000000000004509 106.0
TLS2_k127_2616026_3 Cupin 2, conserved barrel domain protein K16953 - 4.4.1.3 0.000000000000000000004531 103.0
TLS2_k127_2667096_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 337.0
TLS2_k127_2667096_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000691 276.0
TLS2_k127_2667096_2 RNA recognition motif - - - 0.0000000000000000000000000003284 118.0
TLS2_k127_2667096_3 PFAM Formiminotransferase domain, N-terminal subdomain K00603,K01746 - 2.1.2.5,4.3.1.4 0.00000000000001138 82.0
TLS2_k127_2718674_0 PFAM Organic solvent tolerance protein K04744 - - 1.761e-212 685.0
TLS2_k127_276420_0 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002009 253.0
TLS2_k127_276420_1 Domain of unknown function (DUF309) K09763 - - 0.00000000000000000000000000001148 121.0
TLS2_k127_276420_2 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000315 111.0
TLS2_k127_276420_3 - - - - 0.00000000000000000000007369 108.0
TLS2_k127_279186_0 Cytochrome c - - - 4.946e-227 736.0
TLS2_k127_279186_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 520.0
TLS2_k127_279186_2 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000003591 226.0
TLS2_k127_279186_3 transport - - - 0.0000000000000000000000000000000000000000000000000001208 191.0
TLS2_k127_28056_0 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 327.0
TLS2_k127_28056_1 Methyltransferase FkbM domain - - - 0.000000000000000000000002011 114.0
TLS2_k127_28056_2 Integrase core domain - - - 0.000000000000000000000003809 106.0
TLS2_k127_28056_3 Plasmid encoded RepA protein - - - 0.00000000000000000000001256 104.0
TLS2_k127_28056_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - 0.0000000000000001683 87.0
TLS2_k127_28056_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000003244 76.0
TLS2_k127_2807781_0 Pilus assembly protein K02461,K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000004733 244.0
TLS2_k127_2807781_1 protein secretion K02460 - - 0.0000000000000000000000000001707 127.0
TLS2_k127_2807781_2 general secretion pathway protein K02456,K02458,K02459,K10927 - - 0.0000000000000000000000005567 117.0
TLS2_k127_2807781_7 general secretion pathway protein K02246,K02456,K02458 - - 0.0000000004657 60.0
TLS2_k127_2809745_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 472.0
TLS2_k127_2809745_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000000001726 135.0
TLS2_k127_2818476_0 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 324.0
TLS2_k127_2818476_1 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000000000000000000008183 139.0
TLS2_k127_2818476_2 Sel1 domain protein repeat-containing protein K07126,K13582 - - 0.00002064 57.0
TLS2_k127_2818938_0 amine dehydrogenase activity K14647,K21449 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 596.0
TLS2_k127_2818938_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 470.0
TLS2_k127_2818938_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 359.0
TLS2_k127_2818938_3 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 367.0
TLS2_k127_2818938_4 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 336.0
TLS2_k127_2818938_5 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000009682 191.0
TLS2_k127_2818938_6 - - - - 0.000000000000000000000000000000000000000002362 161.0
TLS2_k127_2818938_7 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000006012 166.0
TLS2_k127_2818938_8 RNA recognition motif - - - 0.000000000018 65.0
TLS2_k127_2819387_0 Carboxypeptidase regulatory-like domain - - - 5.832e-224 709.0
TLS2_k127_2819387_1 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 345.0
TLS2_k127_2819387_2 TonB dependent receptor - - - 0.00000000000000000000000000003315 124.0
TLS2_k127_2819387_3 cellulose binding K01342,K20276 - 3.4.21.62 0.000000000000000000000000000653 124.0
TLS2_k127_2826684_0 - - - - 1.421e-199 646.0
TLS2_k127_2826684_1 RNA-binding S4 domain protein K04762 - - 0.0000000000000000000000000000000000000000000000000000001081 197.0
TLS2_k127_2826684_2 Alanine racemase, N-terminal domain K18425,K19967 - 4.1.2.42,4.1.3.41 0.00000000000000000000000000000000000000000000000000009188 198.0
TLS2_k127_2826684_3 PFAM Xylose isomerase - - - 0.000000000000000000003337 104.0
TLS2_k127_2826684_4 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000447 67.0
TLS2_k127_2830793_0 DNA topological change K03168 - 5.99.1.2 1.681e-288 895.0
TLS2_k127_2830793_1 Protein of unknown function (DUF1552) - - - 2.524e-236 736.0
TLS2_k127_2840051_0 Amidohydrolase K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 372.0
TLS2_k127_2840051_1 aldo keto reductase K17744 - 1.1.1.316 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 344.0
TLS2_k127_2840051_2 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000078 166.0
TLS2_k127_2840051_3 PKD domain containing protein - - - 0.000000000000000000000000000000000000000000009287 175.0
TLS2_k127_2840051_4 Putative regulatory protein - - - 0.00000001373 58.0
TLS2_k127_2841666_0 protein kinase activity K13582,K13924 - 2.1.1.80,3.1.1.61 2.504e-232 738.0
TLS2_k127_2841666_1 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 493.0
TLS2_k127_2841666_2 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 413.0
TLS2_k127_2841666_3 - - - - 0.0000000000000000123 95.0
TLS2_k127_2854429_0 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0 1211.0
TLS2_k127_2854429_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1101.0
TLS2_k127_2854429_10 Xylose isomerase domain protein TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000009141 132.0
TLS2_k127_2854429_2 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 604.0
TLS2_k127_2854429_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 518.0
TLS2_k127_2854429_4 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 343.0
TLS2_k127_2854429_5 PFAM Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 330.0
TLS2_k127_2854429_6 ANTAR K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000002701 218.0
TLS2_k127_2854429_7 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000003293 193.0
TLS2_k127_2854429_8 - - - - 0.00000000000000000000000000000000000000001307 162.0
TLS2_k127_2854429_9 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.0000000000000000000000000000001192 127.0
TLS2_k127_2867522_0 alginic acid biosynthetic process K01729 - 4.2.2.3 3.351e-298 926.0
TLS2_k127_2867522_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000001972 192.0
TLS2_k127_2876001_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 334.0
TLS2_k127_2876001_1 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 299.0
TLS2_k127_2876001_2 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000002299 170.0
TLS2_k127_2876001_3 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000000000001358 155.0
TLS2_k127_288068_0 lipopolysaccharide transport K22110 - - 0.0 1170.0
TLS2_k127_288068_1 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 266.0
TLS2_k127_288068_2 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000121 201.0
TLS2_k127_2883308_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 9.415e-218 685.0
TLS2_k127_2883308_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 514.0
TLS2_k127_2883308_2 PFAM NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 456.0
TLS2_k127_2883308_3 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures - - - 0.0000000000000000000000000000000000006889 153.0
TLS2_k127_2883308_4 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures - - - 0.000000000000000000000000000000004799 136.0
TLS2_k127_2883308_5 Ribosomal_S15 K02956 - - 0.0000000000000000000000001865 107.0
TLS2_k127_2886351_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 2.429e-195 617.0
TLS2_k127_2886351_1 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000001154 215.0
TLS2_k127_2886351_3 - - - - 0.0009726 42.0
TLS2_k127_2894916_0 ABC-type Co2 transport system permease component K02007 - - 0.000000000000000000000000006419 117.0
TLS2_k127_2894916_1 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.00000000000000005607 91.0
TLS2_k127_2894916_2 Domain of unknown function (DUF4198) - - - 0.00000001178 65.0
TLS2_k127_2896804_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 469.0
TLS2_k127_2896804_1 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 376.0
TLS2_k127_2896804_2 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 308.0
TLS2_k127_2896804_3 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000008509 221.0
TLS2_k127_2896804_4 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000006525 168.0
TLS2_k127_2896804_5 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.0000000000000000001333 93.0
TLS2_k127_2900264_0 efflux transmembrane transporter activity - - - 8.999e-293 919.0
TLS2_k127_2900264_1 PFAM Integrase catalytic region - - - 0.00000000002306 65.0
TLS2_k127_2902472_0 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 375.0
TLS2_k127_2902472_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000003333 214.0
TLS2_k127_2902472_10 helix_turn_helix, Lux Regulon K03088 - - 0.0000000000000000006999 98.0
TLS2_k127_2902472_11 PFAM TadE family protein K02282 - - 0.0000000000002477 76.0
TLS2_k127_2902472_12 cobalamin-transporting ATPase activity - - - 0.0001065 50.0
TLS2_k127_2902472_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000249 192.0
TLS2_k127_2902472_3 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000000001044 178.0
TLS2_k127_2902472_5 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000000001437 160.0
TLS2_k127_2902472_6 pfam rok K00845 - 2.7.1.2 0.000000000000000000000000000000000000003424 160.0
TLS2_k127_2902472_7 PIN domain - - - 0.000000000000000000000000000000001739 136.0
TLS2_k127_2902472_8 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000339 128.0
TLS2_k127_2902472_9 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000001935 93.0
TLS2_k127_2909884_0 PFAM FAD linked oxidase domain protein - - - 0.0 1020.0
TLS2_k127_2909884_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 579.0
TLS2_k127_2909884_2 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000002474 220.0
TLS2_k127_2909884_3 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000005321 125.0
TLS2_k127_2909884_4 EamA-like transporter family - - - 0.0000000000000000000000000001787 127.0
TLS2_k127_2909884_5 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000009302 118.0
TLS2_k127_2909884_6 EamA-like transporter family - - - 0.00000000000000000000000001478 122.0
TLS2_k127_2909884_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000005622 67.0
TLS2_k127_2910752_0 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 440.0
TLS2_k127_2910752_1 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 349.0
TLS2_k127_2910752_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000004026 145.0
TLS2_k127_2910752_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K21137 - - 0.00000000002635 72.0
TLS2_k127_2912966_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 443.0
TLS2_k127_2912966_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 309.0
TLS2_k127_2912966_2 intracellular protease K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000001524 241.0
TLS2_k127_2912966_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000001253 221.0
TLS2_k127_2912966_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000001467 191.0
TLS2_k127_2912966_5 methyltransferase - - - 0.000000000000000000000000000000000000000000000000242 186.0
TLS2_k127_2912966_6 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000842 156.0
TLS2_k127_2912966_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000009457 127.0
TLS2_k127_2912966_8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000005855 98.0
TLS2_k127_2912966_9 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.000000000000003968 79.0
TLS2_k127_2913761_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 333.0
TLS2_k127_2913761_1 MarR family - - - 0.000000000000000000000000000000000000000000000000000000000000006292 220.0
TLS2_k127_2913761_2 - - - - 0.00000000001937 64.0
TLS2_k127_2923971_0 Carboxyl transferase domain - - - 2.501e-220 693.0
TLS2_k127_2923971_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000006666 112.0
TLS2_k127_2923971_2 PQQ-like domain - - - 0.00000000006882 73.0
TLS2_k127_2934038_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 586.0
TLS2_k127_2934038_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 310.0
TLS2_k127_2934038_2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K17736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 321.0
TLS2_k127_2934038_3 NHL repeat - - - 0.00000000000000000000000000000000000000000006757 163.0
TLS2_k127_2934038_4 YceI-like domain - - - 0.0000000000000000000000000000000000000000002547 166.0
TLS2_k127_2946697_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.374e-260 818.0
TLS2_k127_2946697_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 453.0
TLS2_k127_2946697_2 flagellar basal-body rod protein FlgG K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 402.0
TLS2_k127_2946697_3 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 342.0
TLS2_k127_2946697_4 basal body rod protein K02391,K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000001092 230.0
TLS2_k127_2946697_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000000000000000002909 196.0
TLS2_k127_2946697_6 Chaperone for flagella basal body P-ring formation K02386 - - 0.00000000000000000000000000000000001983 146.0
TLS2_k127_2946697_7 Flagellar protein FliS K02422 - - 0.0000000000000000000008859 99.0
TLS2_k127_2946697_8 flagellar motor switch protein FliM K02416 - - 0.0000000000000000001065 101.0
TLS2_k127_2946697_9 Rod binding protein - - - 0.00000005463 62.0
TLS2_k127_2954777_0 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 2.783e-226 724.0
TLS2_k127_2954777_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.025e-202 643.0
TLS2_k127_2954777_10 - - - - 0.00001506 49.0
TLS2_k127_2954777_2 Wzt C-terminal domain K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 507.0
TLS2_k127_2954777_3 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 463.0
TLS2_k127_2954777_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 395.0
TLS2_k127_2954777_5 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 399.0
TLS2_k127_2954777_6 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 391.0
TLS2_k127_2954777_7 - - - - 0.000000000000000000000000000000000000000000000002899 176.0
TLS2_k127_2954777_9 Belongs to the UPF0235 family K09131 - - 0.00000000000000000001764 94.0
TLS2_k127_295788_0 Methyltransferase K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 394.0
TLS2_k127_2962301_0 B12 binding domain - - - 3.666e-218 687.0
TLS2_k127_2962301_1 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 464.0
TLS2_k127_2962301_10 COG0784 FOG CheY-like receiver - - - 0.0000000000000000000000000000000000000000002133 167.0
TLS2_k127_2962301_11 LysE type translocator - - - 0.000000000000000000000000003666 114.0
TLS2_k127_2962301_12 B12 binding domain - - - 0.00000000000000000003331 93.0
TLS2_k127_2962301_2 Response regulator receiver modulated diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 458.0
TLS2_k127_2962301_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 411.0
TLS2_k127_2962301_4 peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 354.0
TLS2_k127_2962301_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 344.0
TLS2_k127_2962301_6 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 304.0
TLS2_k127_2962301_7 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 296.0
TLS2_k127_2962301_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000004052 219.0
TLS2_k127_2962301_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000001375 204.0
TLS2_k127_2971682_0 PFAM FAD dependent oxidoreductase - - - 1.987e-214 677.0
TLS2_k127_2971682_1 MASE1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 582.0
TLS2_k127_2971682_10 positive regulation of MDA-5 signaling pathway K16726 GO:0000785,GO:0001568,GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0001817,GO:0001819,GO:0001944,GO:0001955,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002831,GO:0002833,GO:0003674,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0006275,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007346,GO:0007399,GO:0007423,GO:0007492,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010506,GO:0010507,GO:0010556,GO:0010564,GO:0010639,GO:0010646,GO:0010647,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0012505,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031329,GO:0031330,GO:0031347,GO:0031349,GO:0031430,GO:0031672,GO:0031674,GO:0031965,GO:0031967,GO:0031975,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0039531,GO:0039533,GO:0039535,GO:0040011,GO:0042692,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043122,GO:0043123,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043900,GO:0043902,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045214,GO:0045595,GO:0045596,GO:0045787,GO:0045931,GO:0046530,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050688,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051147,GO:0051148,GO:0051150,GO:0051151,GO:0051171,GO:0051239,GO:0051240,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055001,GO:0055002,GO:0060255,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071695,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090068,GO:0090596,GO:0097435,GO:0098542,GO:0099080,GO:0099081,GO:0099512,GO:1900087,GO:1900245,GO:1900246,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902531,GO:1902533,GO:1902806,GO:1902808,GO:1903146,GO:1903147,GO:2000045,GO:2000112 - 0.000000000000000000009765 107.0
TLS2_k127_2971682_11 - - - - 0.00000000000000000004506 97.0
TLS2_k127_2971682_12 Histidine kinase K07683 - 2.7.13.3 0.00000000001635 74.0
TLS2_k127_2971682_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 547.0
TLS2_k127_2971682_3 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 457.0
TLS2_k127_2971682_4 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 312.0
TLS2_k127_2971682_5 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000001009 201.0
TLS2_k127_2971682_6 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000006254 180.0
TLS2_k127_2971682_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000002417 168.0
TLS2_k127_2971682_8 - - - - 0.00000000000000000000000000000002991 138.0
TLS2_k127_2971682_9 - - - - 0.0000000000000000000000000000000803 136.0
TLS2_k127_2971683_0 PFAM AMP-dependent synthetase and ligase K00666 - - 2.363e-291 923.0
TLS2_k127_2971683_1 Major facilitator K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 573.0
TLS2_k127_2971683_2 lipopolysaccharide transport K22110 - - 0.000000000000000000000000000000000000000000000000000000000000000004084 229.0
TLS2_k127_2971683_3 Protein involved in biological_process - - - 0.00000000000000000000000000000000000000000000000009398 181.0
TLS2_k127_2971683_4 pyrroloquinoline quinone binding - - - 0.00000000000000001368 86.0
TLS2_k127_2971683_5 - - - - 0.00000000000001282 81.0
TLS2_k127_2971683_6 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.00000004095 58.0
TLS2_k127_2971683_7 KR domain K00059 - 1.1.1.100 0.000000291 52.0
TLS2_k127_2980289_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 565.0
TLS2_k127_2980289_1 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003203 255.0
TLS2_k127_2981614_0 DNA polymerase X K02347 - - 5.535e-222 702.0
TLS2_k127_2981614_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 547.0
TLS2_k127_2981614_2 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000133 158.0
TLS2_k127_2996989_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 388.0
TLS2_k127_2996989_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 335.0
TLS2_k127_2996989_2 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000000000005643 163.0
TLS2_k127_3000180_0 cell adhesion involved in biofilm formation K01186 - 3.2.1.18 0.00000000000000000000000000000000000000004411 174.0
TLS2_k127_3000180_1 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000004509 154.0
TLS2_k127_3000180_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00002023 58.0
TLS2_k127_3000180_3 PFAM Tetratricopeptide repeat - - - 0.0005274 48.0
TLS2_k127_3000208_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 575.0
TLS2_k127_3000208_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 582.0
TLS2_k127_3000208_10 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000003669 55.0
TLS2_k127_3000208_11 - - - - 0.00008506 49.0
TLS2_k127_3000208_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 468.0
TLS2_k127_3000208_3 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 406.0
TLS2_k127_3000208_4 von Willebrand factor type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001012 254.0
TLS2_k127_3000208_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000008674 222.0
TLS2_k127_3000208_6 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000218 194.0
TLS2_k127_3000208_7 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000009811 153.0
TLS2_k127_3000208_8 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000000001342 134.0
TLS2_k127_300326_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 358.0
TLS2_k127_300326_2 histidine kinase internal region - - - 0.0000000000000000000000000000000000000000000000000000000001918 218.0
TLS2_k127_300326_3 YqcI/YcgG family - - - 0.000000000000000000000000000000000000000000000000000000005416 207.0
TLS2_k127_300326_4 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000005575 208.0
TLS2_k127_300326_5 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000002913 203.0
TLS2_k127_300326_6 Disulfide bond formation protein DsbB K03611 - - 0.00000000000000000000000000000000000000001306 157.0
TLS2_k127_300326_7 multi-organism process K12063 - - 0.000001858 51.0
TLS2_k127_3017525_0 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.0000000000000000000000000000000000000000000000000000000000000000004513 237.0
TLS2_k127_3017525_1 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000009652 206.0
TLS2_k127_3017525_2 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.000000000000000000000000000000000000000000000003736 180.0
TLS2_k127_3017525_3 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000001167 138.0
TLS2_k127_3019632_0 Multicopper K04753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 482.0
TLS2_k127_3019632_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003451 254.0
TLS2_k127_3019632_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000005744 96.0
TLS2_k127_3019632_4 response regulator, receiver K07315 - 3.1.3.3 0.0000000546 55.0
TLS2_k127_3030737_0 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 406.0
TLS2_k127_3030737_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 295.0
TLS2_k127_3030737_2 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000003121 158.0
TLS2_k127_3030737_3 Phage shock protein C, PspC K03973 - - 0.0000000000000000004907 90.0
TLS2_k127_3044220_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 421.0
TLS2_k127_3044220_1 aminopeptidase K19689 - - 0.0006452 48.0
TLS2_k127_305714_0 Carboxypeptidase regulatory-like domain - - - 3.36e-297 947.0
TLS2_k127_305714_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 565.0
TLS2_k127_305714_2 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 499.0
TLS2_k127_305714_3 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000001184 207.0
TLS2_k127_305714_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000001783 196.0
TLS2_k127_305714_5 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000002515 170.0
TLS2_k127_305714_6 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000002263 157.0
TLS2_k127_305714_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000002485 149.0
TLS2_k127_305714_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000002962 96.0
TLS2_k127_3063994_0 PFAM TonB-dependent Receptor Plug - - - 1.892e-261 828.0
TLS2_k127_3063994_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 562.0
TLS2_k127_3063994_2 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 536.0
TLS2_k127_3063994_3 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 445.0
TLS2_k127_3063994_4 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 443.0
TLS2_k127_3063994_5 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000000001519 166.0
TLS2_k127_3063994_6 chorismate lyase activity - - - 0.00000000000000000000000000000000389 137.0
TLS2_k127_3066063_0 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 344.0
TLS2_k127_3066063_1 aldo keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 296.0
TLS2_k127_3070783_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 543.0
TLS2_k127_3070783_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 349.0
TLS2_k127_3070783_2 Ferredoxin thioredoxin reductase catalytic beta chain K17892 - 1.8.7.2 0.00000000000000000000000000000000000000000000000000000000002489 208.0
TLS2_k127_3070783_3 LysR substrate binding domain K03717 - - 0.00000000000000000000000000000000000000000000000004667 183.0
TLS2_k127_3070783_4 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000005393 163.0
TLS2_k127_3076479_0 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 621.0
TLS2_k127_3076479_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 467.0
TLS2_k127_3076479_2 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 452.0
TLS2_k127_3076479_3 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 288.0
TLS2_k127_3076479_4 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000002853 235.0
TLS2_k127_3076479_5 Biotin-requiring enzyme - - - 0.0000000000000000000000000000394 123.0
TLS2_k127_3080767_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 415.0
TLS2_k127_3080767_1 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000001369 107.0
TLS2_k127_3086426_0 Protein of unknown function, DUF255 K06888 - - 2.638e-273 863.0
TLS2_k127_3086426_1 COG0451 Nucleoside-diphosphate-sugar K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 447.0
TLS2_k127_3086426_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 292.0
TLS2_k127_3086426_3 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002635 270.0
TLS2_k127_3086426_4 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001182 246.0
TLS2_k127_3086426_5 Highly conserved protein containing a thioredoxin domain K06888,K20948 - - 0.00000000000000000000000000000000000000000000000000000004165 211.0
TLS2_k127_3086426_6 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000001841 182.0
TLS2_k127_3086426_7 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000001182 181.0
TLS2_k127_3086426_8 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000008018 177.0
TLS2_k127_3086426_9 - - - - 0.00000000002853 67.0
TLS2_k127_3095806_0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001659 276.0
TLS2_k127_3095806_1 archaeal or bacterial-type flagellum-dependent cell motility K02556 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009288,GO:0009425,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044425,GO:0044459,GO:0044461,GO:0044463,GO:0044464,GO:0071944,GO:0120100,GO:0120101 - 0.000000000000000000000000000000000000000000000000000000000000000000002395 243.0
TLS2_k127_3095806_2 Flagellar hook-associated protein 2 N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000156 247.0
TLS2_k127_3095806_3 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000005633 185.0
TLS2_k127_3095806_4 Flagellar basal body-associated protein FliL K02415 - - 0.0000000000000233 79.0
TLS2_k127_3116235_1 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000009222 137.0
TLS2_k127_3116235_2 Polysaccharide pyruvyl transferase - - - 0.00000000000001418 87.0
TLS2_k127_3132668_0 TonB-dependent receptor - - - 9.81e-243 789.0
TLS2_k127_3132668_1 RES domain - - - 0.0000000000000000000000000000000000000001604 157.0
TLS2_k127_3132668_2 inorganic diphosphatase activity K05521 - 3.2.2.24 0.00000000000000000002618 94.0
TLS2_k127_3132668_3 Domain of unknown function (DUF892) - - - 0.000000000000000003782 87.0
TLS2_k127_3132668_4 - - - - 0.00000000000003332 78.0
TLS2_k127_3132668_5 gluconolactonase activity K08884 - 2.7.11.1 0.000001146 57.0
TLS2_k127_3144104_0 COG2382 Enterochelin esterase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 552.0
TLS2_k127_3144104_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000009258 165.0
TLS2_k127_3146945_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 514.0
TLS2_k127_3146945_1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 409.0
TLS2_k127_3146945_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000512 153.0
TLS2_k127_3146945_3 cheY-homologous receiver domain - - - 0.0000007764 55.0
TLS2_k127_3146945_4 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0009972 45.0
TLS2_k127_3155687_0 transport - - - 9.844e-214 688.0
TLS2_k127_3161613_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 556.0
TLS2_k127_3161613_1 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000004538 261.0
TLS2_k127_3161613_2 translation release factor activity K03265 - - 0.000000000000000000001766 106.0
TLS2_k127_31618_0 Transketolase, thiamine diphosphate binding domain - - - 0.0 1027.0
TLS2_k127_31618_1 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 1.931e-251 822.0
TLS2_k127_31618_10 Glycosyl transferase family 41 - - - 0.000000000116 75.0
TLS2_k127_31618_2 PQQ-like domain K00114 - 1.1.2.8 1.511e-201 641.0
TLS2_k127_31618_3 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 591.0
TLS2_k127_31618_4 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 564.0
TLS2_k127_31618_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 475.0
TLS2_k127_31618_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 403.0
TLS2_k127_31618_7 Ectoine synthase - - - 0.000000000000000000000000000000000000000000000000000000000006416 209.0
TLS2_k127_31618_8 Putative inner membrane exporter, YdcZ K09936 - - 0.00000000000000000000000000000000000000000000000000000000003011 208.0
TLS2_k127_31618_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000001505 181.0
TLS2_k127_3171195_0 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 375.0
TLS2_k127_3171195_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000000000000000000008067 202.0
TLS2_k127_3171195_2 - - - - 0.0000000000000000000000000000000000000009779 152.0
TLS2_k127_3171195_3 recA bacterial DNA recombination protein - - - 0.00000000000000000000000000000000001942 144.0
TLS2_k127_3183324_0 alpha-L-rhamnosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 357.0
TLS2_k127_3183324_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.00000000000000000000000000000002349 126.0
TLS2_k127_3186346_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 475.0
TLS2_k127_3186346_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 469.0
TLS2_k127_3186346_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000001033 196.0
TLS2_k127_3186346_3 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000002412 195.0
TLS2_k127_3186346_4 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000001138 179.0
TLS2_k127_3186346_5 - - - - 0.0000000000000000000000000000000000000008231 156.0
TLS2_k127_3186346_6 - - - - 0.0000000000000000000001066 105.0
TLS2_k127_3189923_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 438.0
TLS2_k127_3189923_1 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000009748 134.0
TLS2_k127_3189923_2 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00001934 48.0
TLS2_k127_3194383_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 6.882e-199 636.0
TLS2_k127_3194383_1 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 337.0
TLS2_k127_3194383_2 ABC transporter K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003602 274.0
TLS2_k127_3194383_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001842 245.0
TLS2_k127_3194383_4 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000006465 215.0
TLS2_k127_3194383_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000003218 191.0
TLS2_k127_3194383_6 - - - - 0.0000000000000000000001538 109.0
TLS2_k127_3195921_0 serine-type peptidase activity K06978,K21105 - 3.1.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 304.0
TLS2_k127_3195921_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003357 275.0
TLS2_k127_3195921_10 PFAM TPR repeat-containing protein - - - 0.00000000000000000001655 96.0
TLS2_k127_3195921_11 TIGRFAM TonB family protein K03832 - - 0.0000000000000000001411 101.0
TLS2_k127_3195921_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005277 272.0
TLS2_k127_3195921_3 Protein of unknown function (DUF3891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000499 257.0
TLS2_k127_3195921_4 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000005558 234.0
TLS2_k127_3195921_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000009557 225.0
TLS2_k127_3195921_6 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000002424 186.0
TLS2_k127_3195921_7 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000001599 158.0
TLS2_k127_3195921_8 - - - - 0.00000000000000000000000000000002154 128.0
TLS2_k127_3195921_9 TPR repeat - - - 0.000000000000000000001237 107.0
TLS2_k127_3198659_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 441.0
TLS2_k127_3198659_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 401.0
TLS2_k127_3198659_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000005102 138.0
TLS2_k127_3212861_0 cytochrome C - - - 1.486e-222 725.0
TLS2_k127_3212861_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 551.0
TLS2_k127_3212861_2 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 499.0
TLS2_k127_3212861_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 487.0
TLS2_k127_3212861_4 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 396.0
TLS2_k127_3212861_5 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 359.0
TLS2_k127_3212861_6 FtsX-like permease family - - - 0.000000000000000000000000000000000705 138.0
TLS2_k127_3212861_7 Leucine Rich repeat - - - 0.00000000000000000003993 105.0
TLS2_k127_3212861_8 regulation of response to stimulus - - - 0.000000007563 69.0
TLS2_k127_3216308_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1106.0
TLS2_k127_3216308_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 501.0
TLS2_k127_3216308_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 474.0
TLS2_k127_3216308_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 457.0
TLS2_k127_3216308_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 420.0
TLS2_k127_3216308_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003457 270.0
TLS2_k127_3216308_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000002888 199.0
TLS2_k127_3216308_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000004577 192.0
TLS2_k127_3216308_8 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000005194 145.0
TLS2_k127_3218644_0 efflux transmembrane transporter activity - - - 2.802e-223 721.0
TLS2_k127_3218644_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 583.0
TLS2_k127_3218644_2 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000003065 142.0
TLS2_k127_3218644_3 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000002142 98.0
TLS2_k127_3240343_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 3.064e-194 610.0
TLS2_k127_3240343_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000002983 168.0
TLS2_k127_3247792_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 481.0
TLS2_k127_3247792_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 461.0
TLS2_k127_3247792_2 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002819 261.0
TLS2_k127_3247792_3 - - - - 0.000004995 55.0
TLS2_k127_3254041_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 599.0
TLS2_k127_3254041_1 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 311.0
TLS2_k127_3254041_2 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000004563 217.0
TLS2_k127_3254041_3 oxidoreductase activity K07114 - - 0.00000000000006946 85.0
TLS2_k127_3254041_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000008349 64.0
TLS2_k127_3256551_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 499.0
TLS2_k127_3256551_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 453.0
TLS2_k127_3256551_2 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 452.0
TLS2_k127_3256551_3 - - - - 0.0000000000000000000000000000000000000000000000008009 180.0
TLS2_k127_3269514_0 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 451.0
TLS2_k127_3269514_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 444.0
TLS2_k127_3269514_2 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 329.0
TLS2_k127_3269514_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000007137 241.0
TLS2_k127_3269514_4 Tetratricopeptide repeat - - - 0.00000000000000000005936 105.0
TLS2_k127_3269514_5 domain protein K14475 - - 0.000000000007092 71.0
TLS2_k127_3269514_6 ABC transporter K01989 - - 0.0000009192 60.0
TLS2_k127_3269514_7 peptidase K01303 - 3.4.19.1 0.00004461 53.0
TLS2_k127_3269514_8 WD40-like Beta Propeller Repeat - - - 0.0001765 46.0
TLS2_k127_3269740_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 403.0
TLS2_k127_3269740_1 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 342.0
TLS2_k127_3269740_2 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001095 291.0
TLS2_k127_3269740_3 - - - - 0.000001454 59.0
TLS2_k127_3271364_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 494.0
TLS2_k127_3271364_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000002799 213.0
TLS2_k127_3271364_2 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000000000000000005894 194.0
TLS2_k127_3271364_3 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000227 188.0
TLS2_k127_3271364_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000006483 177.0
TLS2_k127_3271364_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00001965 48.0
TLS2_k127_3274826_0 transcription factor binding - - - 1.201e-197 627.0
TLS2_k127_3274826_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 345.0
TLS2_k127_3274826_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000003505 211.0
TLS2_k127_3274826_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000006313 212.0
TLS2_k127_3274826_4 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000000001755 205.0
TLS2_k127_3274826_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000004042 133.0
TLS2_k127_3274826_6 manually curated - - - 0.0000001116 53.0
TLS2_k127_3274826_7 - - - - 0.000002008 57.0
TLS2_k127_3275983_0 Alpha/beta hydrolase family K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 481.0
TLS2_k127_3275983_1 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 473.0
TLS2_k127_3275983_2 Methyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002297 236.0
TLS2_k127_3284740_0 Ftsk_gamma K03466 - - 6.819e-253 801.0
TLS2_k127_3284740_1 Belongs to the IlvD Edd family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 581.0
TLS2_k127_3284740_2 binding domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 505.0
TLS2_k127_3284740_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001913 267.0
TLS2_k127_3284740_4 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000002766 104.0
TLS2_k127_328575_0 MacB-like periplasmic core domain - - - 6.102e-301 945.0
TLS2_k127_328575_1 MacB-like periplasmic core domain - - - 1.214e-242 781.0
TLS2_k127_328575_2 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 339.0
TLS2_k127_328575_3 K -dependent Na Ca exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 319.0
TLS2_k127_328575_4 transcriptional regulator PadR family - - - 0.00000000000000000000000000000000000000000000000002561 180.0
TLS2_k127_328575_5 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000006055 156.0
TLS2_k127_328575_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000001131 100.0
TLS2_k127_328575_7 Polymer-forming cytoskeletal - - - 0.00000000006753 74.0
TLS2_k127_328575_8 - - - - 0.00000002359 59.0
TLS2_k127_328575_9 - - - - 0.000005759 57.0
TLS2_k127_32984_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.822e-266 839.0
TLS2_k127_32984_1 Ribosomal protein S1 K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 599.0
TLS2_k127_32984_10 - - - - 0.00000000000000000000000000000000000000001741 158.0
TLS2_k127_32984_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000000959 150.0
TLS2_k127_32984_12 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000001447 119.0
TLS2_k127_32984_13 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000007601 104.0
TLS2_k127_32984_14 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000003328 103.0
TLS2_k127_32984_15 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000005702 64.0
TLS2_k127_32984_16 mRNA binding - - - 0.0002187 46.0
TLS2_k127_32984_2 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 561.0
TLS2_k127_32984_3 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 298.0
TLS2_k127_32984_4 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002122 256.0
TLS2_k127_32984_5 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000002697 226.0
TLS2_k127_32984_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000107 187.0
TLS2_k127_32984_7 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000003582 188.0
TLS2_k127_32984_8 FMN reductase (NADPH) activity K00299,K16902 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006790,GO:0006805,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008752,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009111,GO:0009267,GO:0009308,GO:0009310,GO:0009410,GO:0009605,GO:0009970,GO:0009987,GO:0009991,GO:0010181,GO:0016043,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019439,GO:0019694,GO:0019752,GO:0022607,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032787,GO:0033554,GO:0034641,GO:0036094,GO:0042178,GO:0042221,GO:0042365,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0042594,GO:0043167,GO:0043168,GO:0043420,GO:0043421,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046306,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0052873,GO:0055114,GO:0065003,GO:0070887,GO:0071466,GO:0071496,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.1.38,1.5.1.45 0.00000000000000000000000000000000000000000000002705 176.0
TLS2_k127_32984_9 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000003007 179.0
TLS2_k127_3309096_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 481.0
TLS2_k127_3309096_1 mandelate racemase muconate lactonizing K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 312.0
TLS2_k127_3309096_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 310.0
TLS2_k127_3309096_3 Belongs to the IlvD Edd family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003718 278.0
TLS2_k127_3337991_0 PFAM NHL repeat containing protein K13735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001334 300.0
TLS2_k127_3337991_1 Mandelate racemase muconate lactonizing enzyme, N-terminal domain K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001365 263.0
TLS2_k127_3337991_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000105 203.0
TLS2_k127_3337991_3 transposition K07497 - - 0.00000000000000000000000000000000000000003486 157.0
TLS2_k127_3337991_4 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000005924 146.0
TLS2_k127_3337991_5 Integrase - - - 0.00000000000000000000001256 104.0
TLS2_k127_3337991_6 Transcriptional regulator - - - 0.00000000000000005839 87.0
TLS2_k127_3337991_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000004917 64.0
TLS2_k127_3337991_8 AAA ATPase domain - - - 0.0000000004945 61.0
TLS2_k127_3337991_9 transcriptional regulatory protein K02475 - - 0.0000007086 54.0
TLS2_k127_3347273_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 385.0
TLS2_k127_3347273_1 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 310.0
TLS2_k127_3347273_2 PFAM Myo-inositol catabolism IolB domain protein K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000006652 192.0
TLS2_k127_3347273_3 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000305 149.0
TLS2_k127_3347273_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000006016 134.0
TLS2_k127_3347273_6 Redoxin - - - 0.000000000000000000000000004263 124.0
TLS2_k127_3347273_7 Belongs to the Nudix hydrolase family - - - 0.000000000000000000002486 101.0
TLS2_k127_3347273_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000118 62.0
TLS2_k127_3347273_9 Disulphide bond corrector protein DsbC - - - 0.00001122 57.0
TLS2_k127_3352607_0 efflux transmembrane transporter activity - - - 1.557e-271 862.0
TLS2_k127_3352607_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 5.683e-200 651.0
TLS2_k127_3352607_10 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000001033 167.0
TLS2_k127_3352607_11 MaoC like domain - - - 0.00000000000000000000000000000000000000000003139 166.0
TLS2_k127_3352607_12 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000004569 138.0
TLS2_k127_3352607_13 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000006093 110.0
TLS2_k127_3352607_2 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 565.0
TLS2_k127_3352607_3 ketone body catabolic process K01026,K19709 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008410,GO:0008775,GO:0009987,GO:0016043,GO:0016740,GO:0016782,GO:0019752,GO:0022607,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840 2.8.3.1,2.8.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 472.0
TLS2_k127_3352607_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 456.0
TLS2_k127_3352607_5 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 421.0
TLS2_k127_3352607_6 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 405.0
TLS2_k127_3352607_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000001114 205.0
TLS2_k127_3352607_8 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000008304 184.0
TLS2_k127_3352607_9 Alpha beta hydrolase fold-3 domain protein - - - 0.0000000000000000000000000000000000000000000009223 169.0
TLS2_k127_3354353_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 482.0
TLS2_k127_3354353_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 425.0
TLS2_k127_3354353_10 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000001827 156.0
TLS2_k127_3354353_11 Cyclophilin-like K09143 - - 0.0000000000000000000000000005052 117.0
TLS2_k127_3354353_12 Glycosyl transferase, family 2 - - - 0.0000000000002981 81.0
TLS2_k127_3354353_13 Polysaccharide biosynthesis protein - - - 0.00000000001915 73.0
TLS2_k127_3354353_14 polysaccharide biosynthetic process - - - 0.00000000003648 75.0
TLS2_k127_3354353_15 dtdp-glucose 4,6-dehydratase - - - 0.0000003138 62.0
TLS2_k127_3354353_16 O-Antigen ligase - - - 0.0000005004 62.0
TLS2_k127_3354353_17 COG0489 ATPases involved in chromosome partitioning K00903 - 2.7.10.2 0.000006251 51.0
TLS2_k127_3354353_18 this gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.0000526 55.0
TLS2_k127_3354353_2 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 388.0
TLS2_k127_3354353_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 385.0
TLS2_k127_3354353_4 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 382.0
TLS2_k127_3354353_5 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 321.0
TLS2_k127_3354353_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 266.0
TLS2_k127_3354353_7 G-rich domain on putative tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000001053 208.0
TLS2_k127_3354353_8 transferase activity, transferring glycosyl groups K01784 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 5.1.3.2 0.0000000000000000000000000000000000000000000000000000004858 211.0
TLS2_k127_3354353_9 Pfam Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000025 204.0
TLS2_k127_3354714_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 372.0
TLS2_k127_3354714_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000004312 265.0
TLS2_k127_3354714_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000001091 222.0
TLS2_k127_3369563_0 Carboxypeptidase regulatory-like domain - - - 0.0 1154.0
TLS2_k127_3369563_1 5'-nucleotidase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 433.0
TLS2_k127_3369563_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 304.0
TLS2_k127_3369563_3 FCD - - - 0.000000000000000000000000000000000000000009299 163.0
TLS2_k127_3390632_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.163e-262 821.0
TLS2_k127_3390632_1 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 404.0
TLS2_k127_3390632_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000003213 233.0
TLS2_k127_3390632_3 - - - - 0.00000000000000009904 81.0
TLS2_k127_3396364_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 519.0
TLS2_k127_3396364_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000007269 216.0
TLS2_k127_3396364_2 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000004677 155.0
TLS2_k127_3396364_3 Thioredoxin reductase K00384 - 1.8.1.9 0.00000000000000008377 83.0
TLS2_k127_34027_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.629e-234 732.0
TLS2_k127_34027_1 ABC transporter transmembrane K18890 - - 4.408e-227 721.0
TLS2_k127_34027_10 DUF218 domain - - - 0.000000000000000000000000000000000000001094 155.0
TLS2_k127_34027_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000001171 139.0
TLS2_k127_34027_12 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000882 115.0
TLS2_k127_34027_13 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000000000001094 102.0
TLS2_k127_34027_14 SpoVT / AbrB like domain - - - 0.00000000000000000000324 94.0
TLS2_k127_34027_15 - - - - 0.0000000000000001689 85.0
TLS2_k127_34027_2 ABC transporter transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 592.0
TLS2_k127_34027_3 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 352.0
TLS2_k127_34027_4 COG1397 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 337.0
TLS2_k127_34027_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001565 273.0
TLS2_k127_34027_6 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002495 274.0
TLS2_k127_34027_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008529 271.0
TLS2_k127_34027_8 - - - - 0.0000000000000000000000000000000000000000000000000001632 192.0
TLS2_k127_34027_9 PIN domain - - - 0.0000000000000000000000000000000000000001241 154.0
TLS2_k127_3414699_0 4Fe-4S dicluster domain K00184 - - 2.598e-261 820.0
TLS2_k127_3414699_1 Polysulphide reductase, NrfD K00185 - - 3.664e-194 612.0
TLS2_k127_343336_0 transport - - - 0.0 1375.0
TLS2_k127_343336_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1245.0
TLS2_k127_343336_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 491.0
TLS2_k127_343336_3 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000000000000002338 201.0
TLS2_k127_3437628_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 315.0
TLS2_k127_3437628_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000004465 225.0
TLS2_k127_3446849_0 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 297.0
TLS2_k127_3446849_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000439 248.0
TLS2_k127_3452962_0 Radical SAM - - - 1.71e-226 711.0
TLS2_k127_3452962_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 418.0
TLS2_k127_3452962_2 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 292.0
TLS2_k127_3452962_3 Bacterial membrane protein, YfhO - - - 0.0000000000000000002451 99.0
TLS2_k127_3471517_0 tRNA methyltransferase complex GCD14 subunit - - - 0.0000000000000000000000003648 116.0
TLS2_k127_3471517_1 energy transducer activity K03832 - - 0.00000000000000000000003351 109.0
TLS2_k127_3471517_2 MacB-like periplasmic core domain - - - 0.000003682 48.0
TLS2_k127_349524_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.634e-204 655.0
TLS2_k127_349524_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 445.0
TLS2_k127_349524_2 PFAM Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 323.0
TLS2_k127_3538007_0 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008792 280.0
TLS2_k127_3538007_1 COG2183 Transcriptional accessory protein - - - 0.00000000000000000000000000000000000000000000000000009478 190.0
TLS2_k127_3538007_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000001941 165.0
TLS2_k127_3538007_3 Resolvase, N terminal domain - - - 0.00000000000000000000000000003392 121.0
TLS2_k127_3538007_4 Aldolase/RraA - - - 0.000000000000000000000002974 104.0
TLS2_k127_3538007_5 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000003033 100.0
TLS2_k127_3538007_6 SBF-like CPA transporter family (DUF4137) K03453,K14347 - - 0.000000001508 65.0
TLS2_k127_3538007_7 Recombinase zinc beta ribbon domain K06400 - - 0.00000001595 64.0
TLS2_k127_354491_0 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 317.0
TLS2_k127_354491_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 303.0
TLS2_k127_354491_2 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000114 209.0
TLS2_k127_354491_3 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000000002253 195.0
TLS2_k127_354491_4 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.0000000000000000000000000000000000000000001131 166.0
TLS2_k127_354491_5 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000005252 109.0
TLS2_k127_354491_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044444,GO:0044464 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000036 72.0
TLS2_k127_354491_7 Cytidyltransferase-related domain protein - - - 0.000000177 58.0
TLS2_k127_3550581_0 PFAM TonB-dependent Receptor K16091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 490.0
TLS2_k127_3550581_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000009194 106.0
TLS2_k127_356147_0 DUF1704 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 616.0
TLS2_k127_356147_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 481.0
TLS2_k127_356147_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000003313 175.0
TLS2_k127_356147_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000007415 159.0
TLS2_k127_358989_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.218e-201 634.0
TLS2_k127_358989_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000001359 256.0
TLS2_k127_358989_2 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000003227 193.0
TLS2_k127_358989_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000001478 180.0
TLS2_k127_358989_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000003048 106.0
TLS2_k127_3625020_0 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 369.0
TLS2_k127_3625020_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 323.0
TLS2_k127_3625020_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001072 157.0
TLS2_k127_3625020_3 TM2 domain - - - 0.000000000000005965 81.0
TLS2_k127_363269_0 Integrase core domain - - - 1.282e-200 636.0
TLS2_k127_363269_1 Bacterial dnaA protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 396.0
TLS2_k127_363269_2 Transcriptional regulator, Crp Fnr family - - - 0.000000000000000000000000000000000000000000000000000000000004757 211.0
TLS2_k127_363269_3 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000001218 207.0
TLS2_k127_364571_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 328.0
TLS2_k127_364571_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000002128 183.0
TLS2_k127_364571_2 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000001684 180.0
TLS2_k127_364571_3 Conserved TM helix - - - 0.000000000000000000000000000000000000000000005636 173.0
TLS2_k127_364571_4 Acts as a magnesium transporter K06213 - - 0.0000000000000000000002105 110.0
TLS2_k127_3653173_0 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 479.0
TLS2_k127_3653173_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 406.0
TLS2_k127_3653173_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 367.0
TLS2_k127_3653173_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 315.0
TLS2_k127_3653173_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000005676 145.0
TLS2_k127_367325_0 ABC transporter K06158 - - 3.447e-248 783.0
TLS2_k127_367325_1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 416.0
TLS2_k127_367325_2 peptidase activity K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000005468 219.0
TLS2_k127_368219_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 490.0
TLS2_k127_368219_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001437 265.0
TLS2_k127_368219_2 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002025 249.0
TLS2_k127_368219_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001627 248.0
TLS2_k127_368219_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000001376 121.0
TLS2_k127_3682254_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 345.0
TLS2_k127_3682254_1 PBS lyase HEAT-like repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 338.0
TLS2_k127_3682254_2 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000005475 223.0
TLS2_k127_3682254_3 Response regulator, receiver - - - 0.000000000000000000000003256 107.0
TLS2_k127_3691625_0 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 340.0
TLS2_k127_3691625_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000003631 196.0
TLS2_k127_3691625_2 protein domain associated with - - - 0.00000002354 57.0
TLS2_k127_3743952_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 453.0
TLS2_k127_3743952_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 327.0
TLS2_k127_3743952_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000257 272.0
TLS2_k127_3743952_3 pathogenesis - - - 0.00000002067 60.0
TLS2_k127_3745003_0 GMC oxidoreductase K06151 - 1.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 481.0
TLS2_k127_3745003_1 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 464.0
TLS2_k127_3745003_2 Gluconate 2-dehydrogenase K06152 - 1.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002504 263.0
TLS2_k127_3745003_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000805 129.0
TLS2_k127_3749495_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 345.0
TLS2_k127_3749495_1 Domain of unknown function (DUF5060) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 342.0
TLS2_k127_3749495_2 Putative Ig domain - - - 0.00000000000000000000000000000000000000000201 177.0
TLS2_k127_3749495_3 TPR repeat - - - 0.00000000000000000000000000000000000001207 168.0
TLS2_k127_3757526_0 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003371 286.0
TLS2_k127_3757526_1 2 iron, 2 sulfur cluster binding K13643 - - 0.00000000000000000000000000000000000000000000000000002816 191.0
TLS2_k127_3757526_2 Bacterial extracellular solute-binding protein K02048 - - 0.000000000000000000000000002936 113.0
TLS2_k127_3757526_3 Carboxypeptidase regulatory-like domain - - - 0.000003608 60.0
TLS2_k127_3757813_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 317.0
TLS2_k127_3757813_2 Belongs to the 'phage' integrase family - - - 0.000000000001433 72.0
TLS2_k127_3757813_3 H( )-stimulated, divalent metal cation uptake system - - - 0.000000004566 59.0
TLS2_k127_375975_0 Uncharacterized protein family (UPF0051) K09014 - - 1.141e-275 854.0
TLS2_k127_375975_1 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 462.0
TLS2_k127_375975_2 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 449.0
TLS2_k127_375975_3 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 376.0
TLS2_k127_375975_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000006016 206.0
TLS2_k127_375975_5 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000002086 191.0
TLS2_k127_375975_6 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000008414 162.0
TLS2_k127_375975_7 - - - - 0.000001945 55.0
TLS2_k127_375975_8 Protein of unknown function (DUF3341) - - - 0.000002001 56.0
TLS2_k127_375975_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00013 51.0
TLS2_k127_3764110_0 Transposase domain (DUF772) K07487 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 293.0
TLS2_k127_3764110_1 unfolded protein binding - - - 0.00000000000000000000000000000000000587 144.0
TLS2_k127_3764110_2 Belongs to the heat shock protein 70 family - - - 0.00000000000000000000000000005663 123.0
TLS2_k127_3765797_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.21e-202 641.0
TLS2_k127_3765797_1 alkaline phosphatase K01113 - 3.1.3.1 6.142e-198 630.0
TLS2_k127_3765797_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 328.0
TLS2_k127_3765797_4 Lipocalin-like domain - - - 0.00000000000000000001024 94.0
TLS2_k127_3765797_5 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000002328 65.0
TLS2_k127_3767220_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 430.0
TLS2_k127_3767220_1 PFAM Cytochrome c assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001082 246.0
TLS2_k127_3767220_2 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009255 245.0
TLS2_k127_3767220_3 ABC transporter K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000001965 219.0
TLS2_k127_3767220_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000002987 201.0
TLS2_k127_3767220_5 - - - - 0.00000000000000000000000000000000000000000232 170.0
TLS2_k127_3767220_6 - - - - 0.00000000000000000003011 100.0
TLS2_k127_3767220_7 cytochrome complex assembly K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.0000000000001372 77.0
TLS2_k127_3767220_8 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000004449 60.0
TLS2_k127_3769403_0 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 320.0
TLS2_k127_3769403_1 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.0000000000000000000000000000000000000043 153.0
TLS2_k127_3769403_2 pyrroloquinoline quinone binding - - - 0.00000001202 59.0
TLS2_k127_3769403_3 WD40-like Beta Propeller - - - 0.0001367 48.0
TLS2_k127_376992_0 MacB-like periplasmic core domain - - - 1.806e-319 995.0
TLS2_k127_376992_1 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000008136 145.0
TLS2_k127_3776042_0 COG0471 Di- and tricarboxylate transporters - - - 3.493e-251 788.0
TLS2_k127_3776042_1 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 464.0
TLS2_k127_3776042_2 Domain of unknown function (DUF202) K00389 - - 0.00000000000004102 76.0
TLS2_k127_3777504_0 Protein of unknown function (DUF1343) - - - 2.651e-255 809.0
TLS2_k127_3777504_1 PFAM aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 516.0
TLS2_k127_3777504_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 506.0
TLS2_k127_3777504_3 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 452.0
TLS2_k127_3777504_4 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 308.0
TLS2_k127_3777504_5 SMART Pyrrolo-quinoline quinone K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000717 236.0
TLS2_k127_3777504_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000003644 214.0
TLS2_k127_3777504_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000008301 218.0
TLS2_k127_3777504_8 mannose-6-phosphate isomerase, class I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000003039 222.0
TLS2_k127_3777504_9 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000028 91.0
TLS2_k127_378520_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 526.0
TLS2_k127_378520_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 526.0
TLS2_k127_378520_2 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 463.0
TLS2_k127_378520_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 389.0
TLS2_k127_378520_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000003177 169.0
TLS2_k127_3786061_0 DNA topological change K03168 - 5.99.1.2 3.229e-291 913.0
TLS2_k127_3786061_1 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 615.0
TLS2_k127_3786061_2 DNA topological change - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 617.0
TLS2_k127_3786061_3 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 512.0
TLS2_k127_3786061_4 Putative esterase - - - 0.000000000002269 80.0
TLS2_k127_3786061_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000001269 64.0
TLS2_k127_3791898_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1044.0
TLS2_k127_3791898_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 531.0
TLS2_k127_3791898_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 435.0
TLS2_k127_3791898_3 Fumarate reductase, iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 362.0
TLS2_k127_3791898_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 365.0
TLS2_k127_3791898_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 311.0
TLS2_k127_3791898_6 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001667 269.0
TLS2_k127_3791898_7 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000002416 241.0
TLS2_k127_3791898_8 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000002409 192.0
TLS2_k127_3791898_9 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000001577 176.0
TLS2_k127_3796047_0 DREV methyltransferase - - - 0.0000000000000000000000000000009515 133.0
TLS2_k127_3796047_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000002157 124.0
TLS2_k127_3796047_2 Glycosyl transferase, family 2 - - - 0.000000000000003616 87.0
TLS2_k127_3796047_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000002189 80.0
TLS2_k127_3796047_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000001992 60.0
TLS2_k127_3797070_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 7.935e-253 794.0
TLS2_k127_3797070_1 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 1.571e-203 646.0
TLS2_k127_3797070_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002982 278.0
TLS2_k127_3797070_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000009228 80.0
TLS2_k127_3805876_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 1.797e-209 676.0
TLS2_k127_3805876_1 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 579.0
TLS2_k127_3805876_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 570.0
TLS2_k127_3805876_3 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 531.0
TLS2_k127_3805876_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 316.0
TLS2_k127_3805876_5 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001207 235.0
TLS2_k127_3805876_6 - - - - 0.0000000000000000000000000000000000000000000000000000000003747 216.0
TLS2_k127_3807202_0 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 392.0
TLS2_k127_3807202_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 372.0
TLS2_k127_3807202_2 amidohydrolase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000785 179.0
TLS2_k127_3807202_3 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000004172 88.0
TLS2_k127_3809302_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 422.0
TLS2_k127_3809302_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 342.0
TLS2_k127_3809302_2 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000724 223.0
TLS2_k127_3809302_3 - K07498 - - 0.00000005125 57.0
TLS2_k127_3809302_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00006615 51.0
TLS2_k127_3818183_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 4.689e-226 708.0
TLS2_k127_3818183_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 505.0
TLS2_k127_3818183_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 335.0
TLS2_k127_3818222_0 TonB-dependent receptor - - - 1.046e-205 681.0
TLS2_k127_3818222_1 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000002207 161.0
TLS2_k127_3818222_2 MacB-like periplasmic core domain - - - 0.000003682 48.0
TLS2_k127_3822465_0 - - - - 3.259e-280 874.0
TLS2_k127_3822465_1 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000004011 205.0
TLS2_k127_3825331_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.958e-210 662.0
TLS2_k127_3825331_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 599.0
TLS2_k127_3825331_2 Doxx family - - - 0.000000000000000000000000000000000000000000000000001035 195.0
TLS2_k127_3825331_4 RecX family K03565 - - 0.000000000000000000006537 100.0
TLS2_k127_3825341_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000001308 221.0
TLS2_k127_3825341_1 COG3119 Arylsulfatase A K01138 - - 0.0000000000000000000000000000000000000000000000000000000000001345 215.0
TLS2_k127_3825341_2 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000000000000000000003524 165.0
TLS2_k127_3833068_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 499.0
TLS2_k127_3833068_1 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 446.0
TLS2_k127_3833068_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000007155 234.0
TLS2_k127_3833068_3 Conserved hypothetical protein (DUF2461) - - - 0.0003059 46.0
TLS2_k127_3838659_0 Beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005575 273.0
TLS2_k127_3838659_1 protein conserved in bacteria - - - 0.00000000000000000000000002716 110.0
TLS2_k127_3843271_0 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 531.0
TLS2_k127_3843271_1 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 385.0
TLS2_k127_3843271_2 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002552 276.0
TLS2_k127_3843271_3 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000003443 158.0
TLS2_k127_3843271_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000001812 147.0
TLS2_k127_3843271_5 regulation of response to stimulus - - - 0.00007487 55.0
TLS2_k127_3845349_0 Protein of unknown function (DUF1501) - - - 1.195e-195 614.0
TLS2_k127_3845349_1 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000009643 120.0
TLS2_k127_3845349_2 Membrane - - - 0.000000000000000000000009633 113.0
TLS2_k127_3845349_3 GntR family transcriptional regulator - - - 0.000000000000000005583 89.0
TLS2_k127_3845519_0 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 426.0
TLS2_k127_3845519_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000004636 155.0
TLS2_k127_3845519_2 O-linked N-acetylglucosamine transferase, SPINDLY family - - - 0.000000000000001551 90.0
TLS2_k127_3846294_0 TPR repeat - - - 0.0000000004512 71.0
TLS2_k127_3846318_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.247e-285 891.0
TLS2_k127_3846318_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 346.0
TLS2_k127_3846318_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000001801 214.0
TLS2_k127_3847888_0 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 312.0
TLS2_k127_3847888_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000000000000000000000000105 238.0
TLS2_k127_3847888_2 - - - - 0.000000000000000000000000000005003 124.0
TLS2_k127_3847888_4 - - - - 0.0000000000000000000000044 106.0
TLS2_k127_3852553_0 Acetokinase family K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 405.0
TLS2_k127_3852553_1 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000005989 126.0
TLS2_k127_3854442_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 524.0
TLS2_k127_3854442_1 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 449.0
TLS2_k127_3854442_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 304.0
TLS2_k127_3854442_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000001681 246.0
TLS2_k127_3854442_4 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000006207 188.0
TLS2_k127_3854442_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000006252 91.0
TLS2_k127_3854442_6 VIT family - - - 0.0000000001 64.0
TLS2_k127_385588_0 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 456.0
TLS2_k127_3857082_0 xanthine dehydrogenase activity - - - 0.0 1136.0
TLS2_k127_3857082_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 2.047e-276 869.0
TLS2_k127_3857082_2 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 390.0
TLS2_k127_3857082_3 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 284.0
TLS2_k127_385759_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.072e-225 702.0
TLS2_k127_385759_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 315.0
TLS2_k127_385759_10 - - - - 0.0000000000000001539 90.0
TLS2_k127_385759_11 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000001722 92.0
TLS2_k127_385759_12 - - - - 0.000000000000001427 87.0
TLS2_k127_385759_14 - - - - 0.00000002274 59.0
TLS2_k127_385759_2 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000395 211.0
TLS2_k127_385759_3 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000003274 196.0
TLS2_k127_385759_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000003161 184.0
TLS2_k127_385759_5 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000000000000000006925 173.0
TLS2_k127_385759_6 RES - - - 0.00000000000000000000000000000000001328 140.0
TLS2_k127_385759_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000001806 117.0
TLS2_k127_385759_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000000000005295 125.0
TLS2_k127_385759_9 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000001488 115.0
TLS2_k127_3859193_0 Cytochrome c - - - 0.0 1090.0
TLS2_k127_3859193_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 484.0
TLS2_k127_3859193_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 482.0
TLS2_k127_3859193_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 331.0
TLS2_k127_3859193_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002156 277.0
TLS2_k127_3859193_5 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005107 260.0
TLS2_k127_3859193_6 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005298 261.0
TLS2_k127_3859193_7 Cytochrome oxidase assembly protein K02259,K03110 - - 0.0000000000000000000000000000000000000000000000000003798 196.0
TLS2_k127_3859193_8 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.0000000000000000000000000000000000000000000000000004191 190.0
TLS2_k127_38623_0 Glycosyl transferase, family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006281 265.0
TLS2_k127_38623_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000002164 231.0
TLS2_k127_38623_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000002161 190.0
TLS2_k127_38623_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000001239 89.0
TLS2_k127_38623_5 Glycosyl transferase family group 2 K07011 - - 0.0006574 46.0
TLS2_k127_3864192_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 584.0
TLS2_k127_3864192_1 protocatechuate 3,4-dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 535.0
TLS2_k127_3864192_2 Belongs to the HpcH HpaI aldolase family K01630,K02510,K12660 - 4.1.2.20,4.1.2.52,4.1.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002956 285.0
TLS2_k127_3864192_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000001211 81.0
TLS2_k127_3866962_0 TonB-dependent receptor - - - 0.0 1210.0
TLS2_k127_3866962_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 3.754e-292 932.0
TLS2_k127_3866962_10 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000008347 136.0
TLS2_k127_3866962_2 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 2.852e-244 765.0
TLS2_k127_3866962_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 484.0
TLS2_k127_3866962_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 447.0
TLS2_k127_3866962_5 protein import - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 410.0
TLS2_k127_3866962_6 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005158 275.0
TLS2_k127_3866962_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002099 259.0
TLS2_k127_3866962_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000001191 204.0
TLS2_k127_3866962_9 Iodothyronine deiodinase - - - 0.0000000000000000000000000000000000009464 147.0
TLS2_k127_3868794_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1155.0
TLS2_k127_3868794_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 426.0
TLS2_k127_3868794_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 303.0
TLS2_k127_3868794_3 NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006568 259.0
TLS2_k127_3868794_4 PIN domain - - - 0.0000000000000000000000000000000004963 138.0
TLS2_k127_3868794_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000007464 92.0
TLS2_k127_3868794_6 Virulence activator alpha C-term - - - 0.0000000000000000006107 94.0
TLS2_k127_3868794_7 PFAM ROK family K00845 - 2.7.1.2 0.0000000001631 65.0
TLS2_k127_3868794_8 FR47-like protein - - - 0.0000001779 59.0
TLS2_k127_3868794_9 Domain of Unknown Function (DUF349) - - - 0.00003329 51.0
TLS2_k127_3870424_0 FtsX-like permease family - - - 6.044e-210 681.0
TLS2_k127_3870424_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 477.0
TLS2_k127_3870424_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 355.0
TLS2_k127_3894229_0 MacB-like periplasmic core domain - - - 0.0 1013.0
TLS2_k127_3894229_1 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 1.618e-218 707.0
TLS2_k127_3894229_2 Aldehyde dehydrogenase family K00131 - 1.2.1.9 9.676e-215 676.0
TLS2_k127_3894229_3 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 597.0
TLS2_k127_3894229_4 OPT oligopeptide transporter protein - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 557.0
TLS2_k127_3894229_5 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K07404 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 391.0
TLS2_k127_3894229_6 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 352.0
TLS2_k127_3894229_7 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 299.0
TLS2_k127_3894229_8 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002246 277.0
TLS2_k127_3894229_9 Protein of unknown function (DUF3467) K06603 - - 0.00000000000000000000000000000000008283 135.0
TLS2_k127_3896679_0 tail sheath protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 612.0
TLS2_k127_3896679_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 571.0
TLS2_k127_3896679_2 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 433.0
TLS2_k127_3896679_3 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 319.0
TLS2_k127_3896679_4 Transposase IS200 like - - - 0.00000000000000000000000000000000000003575 151.0
TLS2_k127_3896679_5 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000329 130.0
TLS2_k127_3896679_6 Sporulation related domain - - - 0.0000000002614 70.0
TLS2_k127_3897636_0 Protein of unknown function (DUF1501) - - - 1.766e-197 625.0
TLS2_k127_3897636_1 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 575.0
TLS2_k127_3897636_2 Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 292.0
TLS2_k127_3897636_3 Helix-turn-helix K21498 - - 0.000000000000000000000000000000000000000000000000000749 186.0
TLS2_k127_3900944_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 597.0
TLS2_k127_3900944_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000007996 145.0
TLS2_k127_3900944_2 light absorption - - - 0.000000000000000000000000000000000001878 141.0
TLS2_k127_3902215_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 526.0
TLS2_k127_3902215_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000001438 155.0
TLS2_k127_3909394_0 LOR/SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 576.0
TLS2_k127_3909394_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 312.0
TLS2_k127_3909394_2 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000001235 269.0
TLS2_k127_3909394_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000001231 226.0
TLS2_k127_3914686_0 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001774 264.0
TLS2_k127_3914686_1 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000002922 213.0
TLS2_k127_3919429_0 Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006241 271.0
TLS2_k127_3919429_1 IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000004662 164.0
TLS2_k127_3919429_3 - - - - 0.00000000003119 71.0
TLS2_k127_3919429_4 ATPase involved in DNA repair - - - 0.0004874 46.0
TLS2_k127_3920278_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 426.0
TLS2_k127_3920278_1 Transposase domain (DUF772) - - - 0.00000000000000000000000000000000000000000000000000000000000001447 233.0
TLS2_k127_3920967_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001427 288.0
TLS2_k127_3920967_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000005582 196.0
TLS2_k127_3920967_2 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000008535 189.0
TLS2_k127_3921050_0 Belongs to the peptidase S8 family K12287 - - 0.000000000000000000000000000002607 141.0
TLS2_k127_3921050_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000305 111.0
TLS2_k127_3921050_2 tail sheath protein - - - 0.00000000000000000000000002351 128.0
TLS2_k127_3921050_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000002286 108.0
TLS2_k127_3925128_0 Protein of unknown function (DUF1501) - - - 1.266e-206 655.0
TLS2_k127_3925128_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003465 242.0
TLS2_k127_3925128_2 sequence-specific DNA binding - - - 0.0000000000000000000000000000000003122 137.0
TLS2_k127_3925128_3 Cytochrome c - - - 0.00000000000000000000818 94.0
TLS2_k127_3929187_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 404.0
TLS2_k127_3929187_1 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 357.0
TLS2_k127_3929187_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 307.0
TLS2_k127_3929187_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000009356 103.0
TLS2_k127_3933303_0 pyridine K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 523.0
TLS2_k127_3933303_1 cellulose binding - - - 0.000000000000000000000000000008301 138.0
TLS2_k127_3942464_0 MacB-like periplasmic core domain - - - 1.476e-286 904.0
TLS2_k127_3942464_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000009175 160.0
TLS2_k127_3942464_2 Metal ion binding. It is involved in the biological process described with oxidation-reduction process K11173 GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006103,GO:0006520,GO:0006536,GO:0006538,GO:0006539,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0047988,GO:0051186,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.99.24 0.0000000000000000000722 90.0
TLS2_k127_3954480_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 429.0
TLS2_k127_3954480_1 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 413.0
TLS2_k127_3954480_2 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000000000000008075 162.0
TLS2_k127_3966248_0 domain, Protein K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 313.0
TLS2_k127_3966248_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000001018 236.0
TLS2_k127_3966248_2 Domain of unknown function (DUF2341) - - - 0.0000000000000000000000000000005987 139.0
TLS2_k127_3974582_0 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 398.0
TLS2_k127_3974582_1 Two component transcriptional regulator, winged helix family K02483,K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 308.0
TLS2_k127_3974582_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 290.0
TLS2_k127_3974582_3 - - - - 0.00000000000000000000000008114 111.0
TLS2_k127_3974582_4 peptidyl-tyrosine sulfation - - - 0.0000000000000006066 89.0
TLS2_k127_3978510_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 558.0
TLS2_k127_3978510_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000007411 181.0
TLS2_k127_3978510_2 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000005269 120.0
TLS2_k127_3978510_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000005413 68.0
TLS2_k127_3979952_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 606.0
TLS2_k127_3979952_1 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 507.0
TLS2_k127_3979952_11 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000002841 50.0
TLS2_k127_3979952_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 347.0
TLS2_k127_3979952_3 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001052 280.0
TLS2_k127_3979952_4 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000002588 175.0
TLS2_k127_3979952_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000004081 162.0
TLS2_k127_3979952_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000002579 134.0
TLS2_k127_3979952_7 - - - - 0.00000000000000000000004082 99.0
TLS2_k127_3979952_9 Peptidoglycan-binding domain 1 protein - - - 0.00000000003162 74.0
TLS2_k127_39859_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 9.361e-207 652.0
TLS2_k127_39859_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 503.0
TLS2_k127_39859_2 PFAM aminotransferase class V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 331.0
TLS2_k127_39859_3 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002692 282.0
TLS2_k127_39859_4 Protein of unknown function (Hypoth_ymh) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009187 248.0
TLS2_k127_3989014_0 AMP-binding enzyme C-terminal domain K00666 - - 1.678e-195 624.0
TLS2_k127_3989014_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 458.0
TLS2_k127_3989014_2 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 419.0
TLS2_k127_3989014_3 4-phosphoerythronate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 336.0
TLS2_k127_3989014_4 Putative serine dehydratase domain - - - 0.000000004104 62.0
TLS2_k127_400549_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 434.0
TLS2_k127_400549_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000001116 145.0
TLS2_k127_400549_2 - - - - 0.00000000000000000000000000000000001328 140.0
TLS2_k127_400549_3 - - - - 0.0000000000000000000000000000001705 132.0
TLS2_k127_400549_5 - - - - 0.000000000000001748 81.0
TLS2_k127_4016217_0 - K13486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 340.0
TLS2_k127_4016217_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 301.0
TLS2_k127_4016217_2 metal cluster binding - - - 0.0000000000000000000000001914 112.0
TLS2_k127_4041792_0 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 316.0
TLS2_k127_4041792_1 Helix-turn-helix domain K07729 - - 0.00000000000000000000000000000000000000000000000000379 186.0
TLS2_k127_4041792_2 Haem-degrading K11477 - - 0.0000000000000000000000000000000000000001854 156.0
TLS2_k127_4041792_3 nucleic acid-binding protein K07066 - - 0.000000000000000000000000000000000001261 144.0
TLS2_k127_4041792_4 Uncharacterised protein family (UPF0175) - - - 0.000000000002045 71.0
TLS2_k127_4051584_0 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 1.142e-257 812.0
TLS2_k127_4051584_1 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000000000007392 172.0
TLS2_k127_4051584_2 DoxX K15977 - - 0.00000000000000000000000000000000000005251 147.0
TLS2_k127_4051584_3 PFAM TonB-dependent Receptor K16091 - - 0.00000000000000000000000000000000004359 141.0
TLS2_k127_4054855_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 521.0
TLS2_k127_4056683_0 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 333.0
TLS2_k127_4056683_1 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000004293 199.0
TLS2_k127_4056683_3 Transcriptional regulator - - - 0.0000000000001251 71.0
TLS2_k127_407050_0 pentaerythritol trinitrate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 588.0
TLS2_k127_407050_1 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 563.0
TLS2_k127_407050_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000001697 254.0
TLS2_k127_407050_11 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001054 253.0
TLS2_k127_407050_12 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000001393 181.0
TLS2_k127_407050_13 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000000000008739 124.0
TLS2_k127_407050_14 mttA/Hcf106 family K03116 - - 0.0000000000000000000000003078 110.0
TLS2_k127_407050_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 462.0
TLS2_k127_407050_3 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 410.0
TLS2_k127_407050_4 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 381.0
TLS2_k127_407050_5 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 373.0
TLS2_k127_407050_6 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 350.0
TLS2_k127_407050_7 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 336.0
TLS2_k127_407050_8 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 324.0
TLS2_k127_407050_9 Sec-independent protein translocase protein (TatC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008096 316.0
TLS2_k127_4071389_0 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 576.0
TLS2_k127_4071389_1 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001577 245.0
TLS2_k127_4071389_2 DinB superfamily - - - 0.000000000000000000000000000000000000000000000008428 176.0
TLS2_k127_4071389_3 Low temperature requirement A - - - 0.00000000000000000000000000000000000000000000002213 186.0
TLS2_k127_4071389_4 - - - - 0.00000000000000000000000000002009 126.0
TLS2_k127_4071389_5 - - - - 0.00000000000002505 78.0
TLS2_k127_4079401_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 2.804e-212 679.0
TLS2_k127_4079401_1 2Fe-2S -binding K13483 - - 0.0000000000000000000000000000000000000000000000000001453 194.0
TLS2_k127_4082207_0 MacB-like periplasmic core domain - - - 3.367e-246 790.0
TLS2_k127_4082207_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000003153 130.0
TLS2_k127_4082207_2 MacB-like periplasmic core domain - - - 0.0000000001709 61.0
TLS2_k127_4084163_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 305.0
TLS2_k127_4084163_1 Serine aminopeptidase, S33 - - - 0.00000000005635 65.0
TLS2_k127_4089235_0 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 539.0
TLS2_k127_4089235_1 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000005083 192.0
TLS2_k127_4092856_0 transport - - - 4.214e-310 985.0
TLS2_k127_4092856_1 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 369.0
TLS2_k127_4092856_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000001073 186.0
TLS2_k127_4092856_3 FCD - - - 0.000000000000000000000000000000000000000001487 169.0
TLS2_k127_4092856_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000001954 154.0
TLS2_k127_4092856_5 Dicarboxylate carrier MatC domain protein - - - 0.00000000000000000001928 94.0
TLS2_k127_4103288_0 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 364.0
TLS2_k127_4103288_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000001927 148.0
TLS2_k127_4103288_2 - - - - 0.00000000000000000003498 102.0
TLS2_k127_4103288_3 Belongs to the HesB IscA family - - - 0.0000000000000000001547 91.0
TLS2_k127_4103288_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000007256 72.0
TLS2_k127_4103288_5 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source K10778 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 2.1.1.63 0.0000000003595 63.0
TLS2_k127_4108095_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 539.0
TLS2_k127_4108095_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 376.0
TLS2_k127_4108095_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 370.0
TLS2_k127_4108095_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 337.0
TLS2_k127_4108095_4 glucosamine-1-phosphate N-acetyltransferase activity K00972,K21379 - 2.3.1.209,2.7.7.23,2.7.7.83 0.0000000000000000000000000000000000000000000000000000000000000000000000002399 263.0
TLS2_k127_4108095_5 cheY-homologous receiver domain - - - 0.00000000000000000000000244 107.0
TLS2_k127_4108730_0 TIGRFAM HipA, N-terminal K07154 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 610.0
TLS2_k127_4108730_1 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 430.0
TLS2_k127_4108730_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000004948 252.0
TLS2_k127_4108730_3 sequence-specific DNA binding - - - 0.000000000000000000000000000000001073 135.0
TLS2_k127_4110954_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 573.0
TLS2_k127_4110954_1 protein kinase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 540.0
TLS2_k127_4110954_10 - - - - 0.00000000000000000000000000006781 120.0
TLS2_k127_4110954_11 Thioesterase superfamily K01075,K07107 - 3.1.2.23 0.000000000000000000006542 98.0
TLS2_k127_4110954_12 - - - - 0.000000000000000008685 85.0
TLS2_k127_4110954_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 482.0
TLS2_k127_4110954_3 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 440.0
TLS2_k127_4110954_4 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 389.0
TLS2_k127_4110954_5 protein kinase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 318.0
TLS2_k127_4110954_6 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 316.0
TLS2_k127_4110954_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 306.0
TLS2_k127_4110954_8 - - - - 0.00000000000000000000000000000000000000000000009464 179.0
TLS2_k127_4110954_9 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.0000000000000000000000000000000000005839 145.0
TLS2_k127_4117252_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 369.0
TLS2_k127_4117252_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 356.0
TLS2_k127_4117252_10 - - - - 0.00000000007374 69.0
TLS2_k127_4117252_2 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 293.0
TLS2_k127_4117252_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 288.0
TLS2_k127_4117252_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008486 275.0
TLS2_k127_4117252_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001545 243.0
TLS2_k127_4117252_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000004654 186.0
TLS2_k127_4117252_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000006266 181.0
TLS2_k127_4117252_8 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000000000000000000003909 171.0
TLS2_k127_4117252_9 Redoxin - - - 0.0000000000006692 79.0
TLS2_k127_4126529_0 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 519.0
TLS2_k127_4126529_1 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000008704 211.0
TLS2_k127_4126529_2 PFAM regulatory protein LuxR - - - 0.00000000000000000006045 94.0
TLS2_k127_4126529_3 SMART Transport-associated and nodulation - - - 0.000000000006417 70.0
TLS2_k127_4130205_0 FMN-dependent dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001366 272.0
TLS2_k127_4130205_1 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000705 227.0
TLS2_k127_4130205_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000006968 123.0
TLS2_k127_4130205_4 Lipocalin-like domain - - - 0.0000872 51.0
TLS2_k127_4132269_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.634e-309 973.0
TLS2_k127_4132269_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 588.0
TLS2_k127_4132269_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 297.0
TLS2_k127_4132269_11 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 295.0
TLS2_k127_4132269_12 peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 293.0
TLS2_k127_4132269_13 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001643 277.0
TLS2_k127_4132269_14 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000055 271.0
TLS2_k127_4132269_15 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000653 224.0
TLS2_k127_4132269_16 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000051 233.0
TLS2_k127_4132269_17 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000001009 224.0
TLS2_k127_4132269_18 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000002564 221.0
TLS2_k127_4132269_19 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000002253 224.0
TLS2_k127_4132269_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 502.0
TLS2_k127_4132269_20 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000001405 205.0
TLS2_k127_4132269_21 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000007359 210.0
TLS2_k127_4132269_22 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000001578 200.0
TLS2_k127_4132269_23 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000005273 191.0
TLS2_k127_4132269_24 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000004171 188.0
TLS2_k127_4132269_25 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000009876 186.0
TLS2_k127_4132269_26 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000004172 184.0
TLS2_k127_4132269_27 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000005905 186.0
TLS2_k127_4132269_28 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000007519 144.0
TLS2_k127_4132269_29 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000001374 145.0
TLS2_k127_4132269_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 480.0
TLS2_k127_4132269_30 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000002957 140.0
TLS2_k127_4132269_31 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000000000000000000000000005078 143.0
TLS2_k127_4132269_32 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000001264 125.0
TLS2_k127_4132269_33 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000002584 123.0
TLS2_k127_4132269_34 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000006112 120.0
TLS2_k127_4132269_35 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000278 100.0
TLS2_k127_4132269_36 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000005641 71.0
TLS2_k127_4132269_37 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000006459 68.0
TLS2_k127_4132269_38 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000002243 70.0
TLS2_k127_4132269_39 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000003924 68.0
TLS2_k127_4132269_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 425.0
TLS2_k127_4132269_40 Ribosomal protein L30 K02907 - - 0.00000000008652 64.0
TLS2_k127_4132269_5 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 410.0
TLS2_k127_4132269_6 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 366.0
TLS2_k127_4132269_7 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 367.0
TLS2_k127_4132269_8 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 359.0
TLS2_k127_4132269_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 324.0
TLS2_k127_4136104_0 PFAM Aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 313.0
TLS2_k127_4136104_1 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000002585 246.0
TLS2_k127_4155777_0 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 386.0
TLS2_k127_4155777_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 370.0
TLS2_k127_4155777_2 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 349.0
TLS2_k127_4155777_3 May be involved in cell division - - - 0.0000000000000000000000000000000000000000005658 166.0
TLS2_k127_4155777_4 - - - - 0.00003064 52.0
TLS2_k127_4162480_0 hydrolase, family 65, central catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 300.0
TLS2_k127_4162480_1 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000002923 90.0
TLS2_k127_4168289_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000003934 207.0
TLS2_k127_4170142_0 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 342.0
TLS2_k127_4170142_1 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006485 265.0
TLS2_k127_4170142_2 - - - - 0.0000000000000001531 87.0
TLS2_k127_4170142_3 FAD dependent oxidoreductase - - - 0.0000007625 51.0
TLS2_k127_4201102_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004727 245.0
TLS2_k127_4201102_1 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000001738 129.0
TLS2_k127_4201102_2 Transcription factor zinc-finger K09981 - - 0.0000000000000001027 87.0
TLS2_k127_4214115_0 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001629 273.0
TLS2_k127_4214115_1 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000000000000000000000000000000376 137.0
TLS2_k127_4217707_0 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 397.0
TLS2_k127_4217707_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 384.0
TLS2_k127_4217707_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 359.0
TLS2_k127_4217707_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 316.0
TLS2_k127_4217707_5 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000000005248 126.0
TLS2_k127_4238720_0 Multicopper oxidase - - - 3.158e-268 841.0
TLS2_k127_4238720_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 451.0
TLS2_k127_4238720_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 359.0
TLS2_k127_4238720_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009658 340.0
TLS2_k127_4238720_4 protein involved in copper resistance K07233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000274 278.0
TLS2_k127_4238720_5 - K02282 - - 0.0000000000000000000000000000000009019 144.0
TLS2_k127_4244089_0 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 3.883e-234 731.0
TLS2_k127_4244089_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 389.0
TLS2_k127_4244089_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 389.0
TLS2_k127_4244089_3 May be involved in the transport of PQQ or its precursor to the periplasm K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000009904 264.0
TLS2_k127_4244089_4 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.000000000000000000000000003172 115.0
TLS2_k127_4244089_5 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.0000003045 59.0
TLS2_k127_4255248_0 Methane oxygenase PmoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000473 261.0
TLS2_k127_4255248_1 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000001568 149.0
TLS2_k127_4255248_2 Dienelactone hydrolase family - - - 0.00000000000007623 83.0
TLS2_k127_4257933_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 286.0
TLS2_k127_4257933_1 IS66 Orf2 like protein K07484 - - 0.00000000000000000000000000000000000000000000000000000006024 198.0
TLS2_k127_4257933_2 protein y4pG y4sC - - - 0.00000000000000000000000000000000000000000000000000004432 192.0
TLS2_k127_4257933_3 Transposase K07483 - - 0.00000000000000000000000000000000000000002476 156.0
TLS2_k127_4257933_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000003299 79.0
TLS2_k127_4262278_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 540.0
TLS2_k127_4268753_0 Putative glutamine amidotransferase - - - 1.387e-224 719.0
TLS2_k127_4268753_1 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 598.0
TLS2_k127_4268753_2 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 507.0
TLS2_k127_4268753_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 434.0
TLS2_k127_4268753_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 336.0
TLS2_k127_4268753_5 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005286 282.0
TLS2_k127_4268753_6 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000007623 231.0
TLS2_k127_4268753_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000002523 222.0
TLS2_k127_4268753_8 domain, Protein - - - 0.000000001432 63.0
TLS2_k127_4270579_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 593.0
TLS2_k127_4270579_1 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 333.0
TLS2_k127_4270579_2 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 320.0
TLS2_k127_4270579_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000002614 240.0
TLS2_k127_4270579_4 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000154 158.0
TLS2_k127_4270579_5 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000171 149.0
TLS2_k127_4270579_6 - - - - 0.000000000000000000278 89.0
TLS2_k127_4277344_0 Carboxypeptidase regulatory-like domain - - - 0.0 1029.0
TLS2_k127_4277344_1 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 379.0
TLS2_k127_4277344_2 FtsX-like permease family - - - 0.000000000000009142 80.0
TLS2_k127_4354506_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.606e-210 667.0
TLS2_k127_4354506_1 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000001155 198.0
TLS2_k127_4354506_2 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000001179 130.0
TLS2_k127_4354506_3 Tellurite resistance protein TehB - - - 0.0000000000000000000000002098 114.0
TLS2_k127_4358057_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 353.0
TLS2_k127_4358057_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000044 293.0
TLS2_k127_4358057_2 eight transmembrane protein EpsH - - - 0.0000000000000000000000000000000000000000000000000000000000000369 224.0
TLS2_k127_4358057_3 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000003717 171.0
TLS2_k127_4358057_4 TIGRFAM EpsI family protein - - - 0.0000000000000000000000000000004787 135.0
TLS2_k127_4358057_5 domain, Protein K19615 - - 0.000000000000000001416 94.0
TLS2_k127_4358318_0 cystathionine gamma-synthase activity K01739,K01740,K01760,K01761,K10764 - 2.5.1.48,2.5.1.49,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 525.0
TLS2_k127_4358318_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 503.0
TLS2_k127_4358318_2 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 446.0
TLS2_k127_4358318_3 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 429.0
TLS2_k127_4358318_4 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 402.0
TLS2_k127_4358787_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 468.0
TLS2_k127_4358787_1 Isocitrate/isopropylmalate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 332.0
TLS2_k127_4358787_2 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 291.0
TLS2_k127_4359896_0 long-chain fatty acid transporting porin activity - - - 8.769e-223 700.0
TLS2_k127_4359896_1 Phosphoinositide phospholipase C, Ca2+-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 350.0
TLS2_k127_4359896_2 Glycosyl transferase family 11 - - - 0.00000000000000000000000000000000000000000000000000002554 199.0
TLS2_k127_4359896_3 Cytochrome c - - - 0.000000000000000000000000001879 113.0
TLS2_k127_4388150_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 392.0
TLS2_k127_4388150_1 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000003861 85.0
TLS2_k127_4388150_2 Glyoxalase-like domain K06996 - - 0.0000000001335 64.0
TLS2_k127_4412481_0 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006261 285.0
TLS2_k127_4416258_0 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000123 240.0
TLS2_k127_4416258_1 - - - - 0.00000000000000000000000000000000000000000000000000002445 195.0
TLS2_k127_44317_0 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 486.0
TLS2_k127_44317_1 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 385.0
TLS2_k127_44317_10 Ca-dependent carbohydrate-binding module xylan-binding - - - 0.0006339 46.0
TLS2_k127_44317_2 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 338.0
TLS2_k127_44317_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 323.0
TLS2_k127_44317_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 329.0
TLS2_k127_44317_5 PFAM Glutamate-cysteine ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000313 286.0
TLS2_k127_44317_6 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002866 254.0
TLS2_k127_44317_7 - K06992 - - 0.0000000000000000000000000000000000000000000000000000000001252 211.0
TLS2_k127_44317_8 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000001496 208.0
TLS2_k127_44317_9 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000008897 140.0
TLS2_k127_45472_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 294.0
TLS2_k127_45472_1 Major facilitator superfamily K02429 - - 0.00000000000000000000000000000000000000000000000000000000000004379 218.0
TLS2_k127_45472_2 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000001231 198.0
TLS2_k127_4549541_0 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000001601 119.0
TLS2_k127_4549541_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000004815 77.0
TLS2_k127_45556_0 Peptidase M1, membrane alanine aminopeptidase - - - 7.769e-209 672.0
TLS2_k127_45556_1 PFAM DeoC LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000001453 171.0
TLS2_k127_45556_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000006602 113.0
TLS2_k127_45639_0 Carboxypeptidase regulatory-like domain - - - 1.518e-252 818.0
TLS2_k127_45639_1 FGGY family of carbohydrate kinases, N-terminal domain K00848 - 2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 520.0
TLS2_k127_45639_2 virulence factor MVIN family protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 379.0
TLS2_k127_45639_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000003989 166.0
TLS2_k127_458112_0 PFAM FAD linked oxidase domain protein - - - 0.0 1032.0
TLS2_k127_458112_1 Acyclic terpene utilisation family protein AtuA - - - 1.243e-214 674.0
TLS2_k127_458112_10 EamA-like transporter family - - - 0.000000000000000000000000008263 123.0
TLS2_k127_458112_11 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000003024 93.0
TLS2_k127_458112_12 Tetratricopeptide repeat - - - 0.000000000000000006714 95.0
TLS2_k127_458112_13 - - - - 0.00000000000000003423 85.0
TLS2_k127_458112_14 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000002609 80.0
TLS2_k127_458112_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 7.032e-213 683.0
TLS2_k127_458112_3 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 374.0
TLS2_k127_458112_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001626 279.0
TLS2_k127_458112_5 electron transfer activity K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000008648 216.0
TLS2_k127_458112_6 PFAM Aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000007161 171.0
TLS2_k127_458112_7 Cupin domain - - - 0.000000000000000000000000000000000000309 143.0
TLS2_k127_458112_8 metal cluster binding K06940 - - 0.0000000000000000000000000000000000009482 143.0
TLS2_k127_458112_9 EamA-like transporter family - - - 0.000000000000000000000000000002571 136.0
TLS2_k127_459512_0 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 332.0
TLS2_k127_459512_1 R COG0457 FOG TPR repeat - - - 0.00000000000000000000000001538 121.0
TLS2_k127_461768_0 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 490.0
TLS2_k127_461768_1 Domain of unknown function (DUF4202) - - - 0.000000000000000000000000000000000000000000000000000000000003507 216.0
TLS2_k127_461768_2 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000008134 190.0
TLS2_k127_4644738_0 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000601 175.0
TLS2_k127_4644738_1 - - - - 0.000000000000000001067 93.0
TLS2_k127_4644738_2 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000089 51.0
TLS2_k127_4688260_0 arylsulfatase activity - - - 2.818e-208 657.0
TLS2_k127_4688260_1 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 328.0
TLS2_k127_4688260_2 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000002608 211.0
TLS2_k127_469112_0 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 302.0
TLS2_k127_469112_1 polysaccharide export K01991,K16552 - - 0.000000000002747 70.0
TLS2_k127_4691650_0 Cytochrome c - - - 1.487e-309 968.0
TLS2_k127_4691650_1 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 566.0
TLS2_k127_4691650_2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 484.0
TLS2_k127_4691650_3 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 421.0
TLS2_k127_4691650_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 301.0
TLS2_k127_4691650_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003265 293.0
TLS2_k127_4691650_6 - - - - 0.0000000000000000000000000000000000000000000007013 177.0
TLS2_k127_4708370_0 Manganese containing catalase K07217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 454.0
TLS2_k127_4708370_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 357.0
TLS2_k127_4708370_2 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003844 240.0
TLS2_k127_470935_0 enterobactin catabolic process K07214,K09689 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 330.0
TLS2_k127_470935_1 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000002832 108.0
TLS2_k127_4709415_0 PFAM Type II secretion system protein E K02652 - - 1.838e-197 622.0
TLS2_k127_4709415_1 type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 439.0
TLS2_k127_4709415_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 297.0
TLS2_k127_4709415_3 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000378 178.0
TLS2_k127_4709415_4 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000001627 151.0
TLS2_k127_4709415_5 ThiS family - - - 0.0000000000004013 72.0
TLS2_k127_4714429_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 537.0
TLS2_k127_4714429_1 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 411.0
TLS2_k127_4714429_2 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 332.0
TLS2_k127_4714429_3 CTP synthase K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001595 254.0
TLS2_k127_4714429_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000003518 188.0
TLS2_k127_4714429_5 - - - - 0.000000000000000000000000000000000000000000001266 170.0
TLS2_k127_4717956_0 Magnesium transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 543.0
TLS2_k127_4717956_1 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000001665 180.0
TLS2_k127_4719669_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005284 239.0
TLS2_k127_4719669_1 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000000000000000000000000000000000000000000001747 237.0
TLS2_k127_4719669_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000005261 62.0
TLS2_k127_4729490_0 PFAM Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 290.0
TLS2_k127_4729490_1 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000003212 216.0
TLS2_k127_4729490_2 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000003019 149.0
TLS2_k127_4729490_3 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.000000000000000006975 87.0
TLS2_k127_4729572_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 300.0
TLS2_k127_4729572_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002867 271.0
TLS2_k127_4729572_2 PFAM Survival protein SurE K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000005002 242.0
TLS2_k127_4729572_3 Aldo/keto reductase family - - - 0.00000000000000000000000000001812 129.0
TLS2_k127_4729572_4 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000006577 77.0
TLS2_k127_4735484_0 ABC transporter transmembrane K11085 - - 8.162e-243 769.0
TLS2_k127_4735484_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 2.548e-199 628.0
TLS2_k127_4735484_2 choline dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 523.0
TLS2_k127_4735671_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1098.0
TLS2_k127_4735671_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 7.208e-318 1003.0
TLS2_k127_4735671_2 PhoPQ-activated pathogenicity-related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 456.0
TLS2_k127_4735671_3 Biotin-lipoyl like K15727 - - 0.00000000000000000000000000000000000000000000000002811 196.0
TLS2_k127_4735671_4 - - - - 0.000000000000000000000001384 105.0
TLS2_k127_4735671_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.00000000000000000001675 99.0
TLS2_k127_4735671_6 PFAM Outer membrane efflux protein K15725 - - 0.0000000000000000004325 101.0
TLS2_k127_4741867_0 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 376.0
TLS2_k127_4741867_1 hydrolase, family 65, central catalytic - - - 0.00000000000000000000000000000000000001883 147.0
TLS2_k127_4745060_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.044e-196 620.0
TLS2_k127_4745060_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005047 245.0
TLS2_k127_4745060_2 Domain of unknown function (DUF362) - - - 0.000000000000000004437 84.0
TLS2_k127_4745139_0 cobalamin-transporting ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004506 276.0
TLS2_k127_4745139_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000004124 173.0
TLS2_k127_4758096_0 Carboxypeptidase regulatory-like domain - - - 2.816e-283 904.0
TLS2_k127_4769482_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 611.0
TLS2_k127_4769482_1 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 445.0
TLS2_k127_477019_0 alginic acid biosynthetic process K01729 - 4.2.2.3 0.0 1054.0
TLS2_k127_477019_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003576 279.0
TLS2_k127_477019_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000005302 265.0
TLS2_k127_477019_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000009056 229.0
TLS2_k127_477019_4 Protein of unknown function (DUF465) - - - 0.00000001645 60.0
TLS2_k127_477019_5 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00008775 46.0
TLS2_k127_4772070_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.154e-222 702.0
TLS2_k127_4772070_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 4.829e-199 629.0
TLS2_k127_4772070_2 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 553.0
TLS2_k127_4772070_3 multi-organism process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003794 249.0
TLS2_k127_4772070_4 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000001683 177.0
TLS2_k127_4772070_5 cellulose binding - - - 0.0000000000000000000000000006005 123.0
TLS2_k127_4772070_6 gluconolactonase activity K14274,K20274 - - 0.00000000000000000000002149 105.0
TLS2_k127_4772070_7 polygalacturonase activity - - - 0.00005595 56.0
TLS2_k127_4772070_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0002942 54.0
TLS2_k127_4774823_0 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 1.337e-265 857.0
TLS2_k127_4774823_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000000000000000000000000000009216 206.0
TLS2_k127_4774823_2 - - - - 0.00000000007831 69.0
TLS2_k127_4777774_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 580.0
TLS2_k127_4777774_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 509.0
TLS2_k127_4777774_10 Ribosomal protein L35 K02916 - - 0.00000000000002379 76.0
TLS2_k127_4777774_11 - - - - 0.0000001217 57.0
TLS2_k127_4777774_12 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000003572 56.0
TLS2_k127_4777774_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 501.0
TLS2_k127_4777774_3 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 445.0
TLS2_k127_4777774_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 356.0
TLS2_k127_4777774_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 332.0
TLS2_k127_4777774_6 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 322.0
TLS2_k127_4777774_7 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0033890,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000001591 219.0
TLS2_k127_4777774_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000003742 158.0
TLS2_k127_4777774_9 - - - - 0.0000000000000000000000000000000000000004699 154.0
TLS2_k127_4783657_1 protocatechuate 3,4-dioxygenase activity - - - 0.00000000000000000000000000000000000001122 150.0
TLS2_k127_47869_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1405.0
TLS2_k127_47869_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000002592 160.0
TLS2_k127_47869_2 - - - - 0.00002028 56.0
TLS2_k127_4790731_0 Sucrose phosphate synthase, sucrose phosphatase-like K00696 - 2.4.1.14 9.956e-269 846.0
TLS2_k127_4790731_1 sucrose synthase K00695 - 2.4.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 600.0
TLS2_k127_4790731_2 PfkB domain protein K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 292.0
TLS2_k127_4790731_3 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006734 280.0
TLS2_k127_4790731_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000001395 244.0
TLS2_k127_4790731_5 membrane - - - 0.00000000000000000000000000000000000000000000000000003861 191.0
TLS2_k127_4790731_6 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000005319 121.0
TLS2_k127_4790731_7 RNA recognition motif - - - 0.000000000000000000000000005329 112.0
TLS2_k127_4790731_8 Transcriptional regulator antitoxin, MazE K07172 - - 0.0000000003962 66.0
TLS2_k127_47915_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 416.0
TLS2_k127_47915_1 pfam abc K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 328.0
TLS2_k127_47915_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 284.0
TLS2_k127_47915_3 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000002205 65.0
TLS2_k127_4793909_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 430.0
TLS2_k127_4798168_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000006515 204.0
TLS2_k127_4798168_1 protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000000001629 186.0
TLS2_k127_4798168_2 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000000000000000543 146.0
TLS2_k127_4807112_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.563e-212 674.0
TLS2_k127_4821987_0 protocatechuate 3,4-dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 517.0
TLS2_k127_4821987_1 MlrC C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000009441 235.0
TLS2_k127_4824465_0 domain, Protein K20276 - - 4.615e-284 895.0
TLS2_k127_4824465_1 PA14 domain - - - 5.177e-279 873.0
TLS2_k127_4824465_10 metallopeptidase activity K03046 - 2.7.7.6 0.00001151 53.0
TLS2_k127_4824465_11 IstB-like ATP binding protein - - - 0.00002902 50.0
TLS2_k127_4824465_2 Carboxypeptidase regulatory-like domain - - - 6.919e-266 855.0
TLS2_k127_4824465_3 PhoD-like phosphatase K01113 - 3.1.3.1 3.6e-218 704.0
TLS2_k127_4824465_4 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 586.0
TLS2_k127_4824465_5 translation initiation factor activity K06370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 316.0
TLS2_k127_4824465_6 Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000002472 123.0
TLS2_k127_4824465_7 xanthine dehydrogenase activity - - - 0.0000000002506 64.0
TLS2_k127_4824465_8 Sulfatase - - - 0.000000005023 65.0
TLS2_k127_4824465_9 - - - - 0.000004111 50.0
TLS2_k127_482538_0 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 528.0
TLS2_k127_482538_1 Dehydrogenase K00114,K17760,K20936,K21676,K22473 - 1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2 0.000000000000000000000000000000000009043 145.0
TLS2_k127_482538_2 Belongs to the IlvD Edd family K22396 - 4.2.1.82 0.000000000000008832 74.0
TLS2_k127_4825750_0 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 494.0
TLS2_k127_4825750_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 316.0
TLS2_k127_4825750_2 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 303.0
TLS2_k127_4825750_3 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001899 283.0
TLS2_k127_4825750_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000005707 204.0
TLS2_k127_4825750_5 DinB family - - - 0.000000000000000000000000000000000009501 142.0
TLS2_k127_4825750_6 Mechanosensitive ion channel - - - 0.00000000000000005251 85.0
TLS2_k127_4832273_0 AcrB/AcrD/AcrF family K03296 - - 7.815e-254 818.0
TLS2_k127_4832273_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 567.0
TLS2_k127_4832273_2 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 374.0
TLS2_k127_4832273_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 307.0
TLS2_k127_4832273_5 PFAM Uncharacterised protein family UPF0150 - - - 0.00000004449 59.0
TLS2_k127_4834750_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 575.0
TLS2_k127_4834750_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 397.0
TLS2_k127_4834750_2 cell redox homeostasis - - - 0.00000000000000000000000000000000000383 144.0
TLS2_k127_4834750_3 TIGRFAM cytochrome c nitrate reductase, small subunit K15876 - - 0.00000000000000000008351 90.0
TLS2_k127_4836762_0 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 460.0
TLS2_k127_4836762_1 PFAM Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002975 278.0
TLS2_k127_4836762_2 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007148 267.0
TLS2_k127_4836762_3 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001647 227.0
TLS2_k127_4836762_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000009553 229.0
TLS2_k127_4836762_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000002213 194.0
TLS2_k127_4837065_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000002684 180.0
TLS2_k127_4837065_1 amino acid K19540 - - 0.0000000003092 62.0
TLS2_k127_4837065_2 Uncharacterised protein family (UPF0175) - - - 0.0000000006684 64.0
TLS2_k127_4837372_0 alpha-N-arabinofuranosidase K01209 - 3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 548.0
TLS2_k127_4837372_1 PFAM Alcohol dehydrogenase K00001,K00008 - 1.1.1.1,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 541.0
TLS2_k127_4837396_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 589.0
TLS2_k127_4837396_1 DNA methylase N-4 N-6 domain protein K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 479.0
TLS2_k127_4837396_10 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000005258 109.0
TLS2_k127_4837396_11 Putative zinc-finger - - - 0.000000000000000004552 94.0
TLS2_k127_4837396_12 Putative adhesin - - - 0.0000000000001949 75.0
TLS2_k127_4837396_13 YceI-like domain - - - 0.0000000007689 67.0
TLS2_k127_4837396_14 - - - - 0.00000003413 61.0
TLS2_k127_4837396_15 Restriction endonuclease XhoI K01155 - 3.1.21.4 0.000002293 52.0
TLS2_k127_4837396_17 - - - - 0.000007993 53.0
TLS2_k127_4837396_2 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 415.0
TLS2_k127_4837396_3 Restriction endonuclease XhoI K01155 - 3.1.21.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002049 271.0
TLS2_k127_4837396_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002108 269.0
TLS2_k127_4837396_5 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008059 248.0
TLS2_k127_4837396_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000008069 233.0
TLS2_k127_4837396_7 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000006363 231.0
TLS2_k127_4837396_8 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000009376 235.0
TLS2_k127_4837396_9 - - - - 0.0000000000000000000000000000000000000009004 158.0
TLS2_k127_4837883_0 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 281.0
TLS2_k127_4837883_1 Met-10+ like-protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003214 231.0
TLS2_k127_4837883_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01707 - 4.2.1.41 0.00000000000000000000000000000000000000000000000018 188.0
TLS2_k127_4838071_0 - - - - 0.000000000000000000000000000000000000000000000000002586 188.0
TLS2_k127_4838071_1 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000002866 171.0
TLS2_k127_4838071_2 sirohydrochlorin cobaltochelatase activity K03795 - 4.99.1.3 0.000000000000000000000000000124 119.0
TLS2_k127_4838071_3 Protein of unknown function (DUF664) - - - 0.000000000000000004986 92.0
TLS2_k127_4838071_4 Protein of unknown function (DUF1328) - - - 0.00000000003904 65.0
TLS2_k127_4841849_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 483.0
TLS2_k127_4841849_1 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 488.0
TLS2_k127_4849952_0 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 304.0
TLS2_k127_4849952_1 TIGRFAM ATP-dependent DNA helicase, RecQ family K03169,K03654 - 3.6.4.12,5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000238 228.0
TLS2_k127_4849952_2 Helix-hairpin-helix motif K02237 - - 0.000000007509 60.0
TLS2_k127_4867409_0 Arginosuccinate synthase K01940 - 6.3.4.5 5.783e-206 649.0
TLS2_k127_4867409_1 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 558.0
TLS2_k127_4867409_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 376.0
TLS2_k127_4867409_3 PIN domain - - - 0.000000000000000000000000004096 115.0
TLS2_k127_4867409_4 - - - - 0.00000000000000000002779 93.0
TLS2_k127_4867409_5 AAA domain K02282 - - 0.00000000000001313 85.0
TLS2_k127_4867409_6 PIN domain - - - 0.0003166 44.0
TLS2_k127_4872525_0 Protein of unknown function, DUF255 K06888 - - 1.167e-202 655.0
TLS2_k127_4872525_1 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 523.0
TLS2_k127_4872525_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 350.0
TLS2_k127_4872525_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000004357 225.0
TLS2_k127_4872525_4 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000009822 181.0
TLS2_k127_4872525_5 TonB-dependent Receptor Plug K02014 - - 0.00000000000000000000000000000000000000000005506 181.0
TLS2_k127_4872525_7 Protein of unknown function (DUF1572) - - - 0.0007365 43.0
TLS2_k127_487531_0 PFAM Peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 392.0
TLS2_k127_487531_1 Redoxin K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000001177 213.0
TLS2_k127_487531_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000006691 138.0
TLS2_k127_4876108_0 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 444.0
TLS2_k127_4876108_1 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 340.0
TLS2_k127_4876108_2 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 342.0
TLS2_k127_4876108_3 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 296.0
TLS2_k127_4876108_4 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003663 268.0
TLS2_k127_4876108_5 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000000000000000006484 220.0
TLS2_k127_4876108_6 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000000000001148 140.0
TLS2_k127_4876108_7 - - - - 0.0000000000000000000004512 98.0
TLS2_k127_4876108_8 Intracellular proteinase inhibitor - - - 0.00000000006694 74.0
TLS2_k127_4877522_0 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 411.0
TLS2_k127_4877522_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 310.0
TLS2_k127_4877522_2 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000684 276.0
TLS2_k127_4877522_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000001681 186.0
TLS2_k127_4888296_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 548.0
TLS2_k127_4888296_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 515.0
TLS2_k127_4888296_2 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 351.0
TLS2_k127_4888296_3 positive regulation of growth rate - - - 0.000000000000000000000000000000000000000000001369 171.0
TLS2_k127_4888296_4 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000007446 161.0
TLS2_k127_4888296_5 Transglycosylase associated protein - - - 0.000000000000000000000000000002135 124.0
TLS2_k127_4888296_6 Dodecin K09165 - - 0.0000000000000000001495 93.0
TLS2_k127_4893215_0 - - - - 5.162e-200 640.0
TLS2_k127_4893215_2 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000004531 80.0
TLS2_k127_4893215_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000001335 71.0
TLS2_k127_4894229_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.733e-225 716.0
TLS2_k127_4894229_1 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 530.0
TLS2_k127_4894229_2 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 417.0
TLS2_k127_4894229_3 Type II restriction enzyme, methylase - - - 0.0000000000000000000000000000000000000001313 153.0
TLS2_k127_4894229_4 - - - - 0.00000000002853 67.0
TLS2_k127_4894229_6 - - - - 0.00000003922 61.0
TLS2_k127_4894229_7 - - - - 0.000002754 57.0
TLS2_k127_489485_0 GMC oxidoreductase - - - 5.423e-301 930.0
TLS2_k127_489485_2 metal ion transmembrane transporter activity - - - 0.000000008634 58.0
TLS2_k127_4904783_0 TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 358.0
TLS2_k127_4904783_1 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000000000000002383 138.0
TLS2_k127_4904783_2 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000005678 98.0
TLS2_k127_4904783_3 Sulfatase - - - 0.000000006939 58.0
TLS2_k127_4915548_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002839 278.0
TLS2_k127_4915548_1 - K02282 - - 0.000000000000000000000000004124 123.0
TLS2_k127_4919264_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1026.0
TLS2_k127_4919264_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 573.0
TLS2_k127_4919264_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 528.0
TLS2_k127_4919264_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 523.0
TLS2_k127_4919264_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 386.0
TLS2_k127_4919264_5 SAD/SRA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001405 259.0
TLS2_k127_4919264_6 MOSC domain - - - 0.00000000000000000000000000007038 121.0
TLS2_k127_4919264_7 Preprotein translocase, YajC K03210 - - 0.0000000000000000000029 99.0
TLS2_k127_4919264_8 Belongs to the ClpA ClpB family - - - 0.00000000000000000008128 96.0
TLS2_k127_4919264_9 TIGRFAM TonB K03832 - - 0.000000000644 61.0
TLS2_k127_4926124_0 GMC oxidoreductase - - - 6.958e-201 642.0
TLS2_k127_4926124_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 602.0
TLS2_k127_4926124_10 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000006 129.0
TLS2_k127_4926124_11 aminopeptidase activity K19701 - 3.4.11.10,3.4.11.6 0.000000000000000001143 102.0
TLS2_k127_4926124_12 regulation of response to stimulus K13730 - - 0.00000000000000568 87.0
TLS2_k127_4926124_13 repeat-containing protein - - - 0.00002912 56.0
TLS2_k127_4926124_14 Belongs to the bacterial solute-binding protein 3 family K02030 - - 0.0000747 47.0
TLS2_k127_4926124_15 Beta-propeller repeat - - - 0.000155 55.0
TLS2_k127_4926124_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 573.0
TLS2_k127_4926124_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 429.0
TLS2_k127_4926124_4 Protein of unknown function (DUF1592) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 342.0
TLS2_k127_4926124_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 274.0
TLS2_k127_4926124_6 RES domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002138 241.0
TLS2_k127_4926124_7 Leucine-rich repeats, outliers - - - 0.000000000000000000000000000000000000000000000000000000000000000005663 250.0
TLS2_k127_4926124_8 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000007067 225.0
TLS2_k127_4926124_9 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000005736 218.0
TLS2_k127_4941121_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 587.0
TLS2_k127_4941121_1 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002854 258.0
TLS2_k127_4941121_2 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001112 260.0
TLS2_k127_4941121_3 pfam abc K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000108 246.0
TLS2_k127_4941121_4 PspC domain - - - 0.00000000000000004049 83.0
TLS2_k127_4941443_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 351.0
TLS2_k127_4941443_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001242 278.0
TLS2_k127_4941443_2 reverse transcriptase - - - 0.00000000000000000000000000000000000000000000000000000000002447 223.0
TLS2_k127_4941443_3 neuron death in response to oxidative stress K01173 - - 0.000000000000000000000000000000000000947 156.0
TLS2_k127_4941443_4 Carbohydrate binding domain - - - 0.0000000000000000000000000000004446 137.0
TLS2_k127_4941443_5 COG2801 Transposase and inactivated derivatives K00986,K07497 - 2.7.7.49 0.00000000000004825 76.0
TLS2_k127_4941443_6 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.000000006356 57.0
TLS2_k127_4941443_8 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0006926 49.0
TLS2_k127_4943416_0 Amidase - - - 2.288e-226 725.0
TLS2_k127_4943416_1 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 611.0
TLS2_k127_4943416_2 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001636 230.0
TLS2_k127_4943416_3 beta-propeller repeat - - - 0.0000000000000000000000000000000000000003122 156.0
TLS2_k127_4945464_0 - - - - 0.000000000000000000000000000000000004494 155.0
TLS2_k127_4945464_1 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000002171 141.0
TLS2_k127_4945464_2 PhoPQ-activated pathogenicity-related protein - - - 0.000000000000000000000721 102.0
TLS2_k127_4945464_4 p-aminobenzoyl-glutamate transporter - - - 0.00001865 53.0
TLS2_k127_4947598_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 559.0
TLS2_k127_4947598_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 326.0
TLS2_k127_4947598_2 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000009713 101.0
TLS2_k127_4952286_0 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 2.108e-217 679.0
TLS2_k127_4952286_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 349.0
TLS2_k127_4952286_2 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 310.0
TLS2_k127_4957850_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 437.0
TLS2_k127_4957850_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000008719 227.0
TLS2_k127_4975581_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 1.277e-243 767.0
TLS2_k127_4975581_1 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 332.0
TLS2_k127_4975581_2 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000001642 235.0
TLS2_k127_4975581_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000001847 214.0
TLS2_k127_4975581_4 dCMP deaminase activity K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000004519 209.0
TLS2_k127_4975581_5 Arylsulfotransferase Ig-like domain K01023 - 2.8.2.22 0.00000000000000000000000000000000000000000000002274 192.0
TLS2_k127_4975581_6 InterPro IPR007367 - - - 0.0000000000000000000000000185 117.0
TLS2_k127_4975581_7 cellulose binding - - - 0.0000000000000000001733 103.0
TLS2_k127_4998937_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 607.0
TLS2_k127_4998937_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 469.0
TLS2_k127_4998937_2 Bacterioferritin comigratory protein K03564 - 1.11.1.15 0.0000000000002196 71.0
TLS2_k127_5000536_0 - - - - 0.0 1069.0
TLS2_k127_5000536_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 7.157e-268 837.0
TLS2_k127_5000536_2 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 450.0
TLS2_k127_5000536_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 407.0
TLS2_k127_5004078_0 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 548.0
TLS2_k127_5004078_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000001018 191.0
TLS2_k127_5004078_2 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000586 120.0
TLS2_k127_5004078_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000003228 108.0
TLS2_k127_5008401_0 gluconolactonase activity K14274,K20274 - - 1.426e-257 837.0
TLS2_k127_5008401_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 490.0
TLS2_k127_5008401_2 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01664 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007006 276.0
TLS2_k127_5008401_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000004637 227.0
TLS2_k127_5008401_4 PFAM Survival protein SurE K03787 - 3.1.3.5 0.000000000000000000000000000000000000000021 157.0
TLS2_k127_5008401_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000002852 137.0
TLS2_k127_503096_0 Acetyl xylan esterase (AXE1) - - - 5.645e-287 897.0
TLS2_k127_503096_1 Cytochrome c - - - 0.00000000000000000000000000007382 122.0
TLS2_k127_5038845_0 SMART Elongator protein 3 MiaB NifB - - - 9.811e-261 811.0
TLS2_k127_5038845_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000005755 237.0
TLS2_k127_5038845_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000007721 201.0
TLS2_k127_5038845_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000004369 187.0
TLS2_k127_5038845_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000001064 135.0
TLS2_k127_5038845_5 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000003305 138.0
TLS2_k127_5038845_6 Major facilitator superfamily - - - 0.0000000000000000000008498 99.0
TLS2_k127_5038845_7 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 0.0000001149 57.0
TLS2_k127_5040035_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 623.0
TLS2_k127_5040035_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 333.0
TLS2_k127_5040035_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006096 271.0
TLS2_k127_5048568_0 POT family K03305 - - 8.759e-218 689.0
TLS2_k127_5048568_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 295.0
TLS2_k127_5048568_2 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000008631 57.0
TLS2_k127_5048568_3 Heat induced stress protein YflT - - - 0.0000007005 54.0
TLS2_k127_506351_0 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001663 241.0
TLS2_k127_506351_1 PIN domain - - - 0.000000000000000000000000000000000000000000000000000007201 192.0
TLS2_k127_506351_2 YtxH-like protein - - - 0.000003205 51.0
TLS2_k127_506351_3 TIGRFAM transcriptional regulator, AbrB family - - - 0.0002299 47.0
TLS2_k127_506351_4 Protein conserved in bacteria - - - 0.0005959 50.0
TLS2_k127_5065179_0 Pyrrolo-quinoline quinone K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 550.0
TLS2_k127_5065179_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 407.0
TLS2_k127_5065179_2 PFAM Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 394.0
TLS2_k127_5065179_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000009669 247.0
TLS2_k127_5065179_4 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000001401 226.0
TLS2_k127_5065179_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000602 191.0
TLS2_k127_5065179_6 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000001073 155.0
TLS2_k127_5078788_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 5.802e-211 673.0
TLS2_k127_5078788_1 nucleic-acid-binding protein contains PIN domain - - - 0.00000000000000000000000000007505 119.0
TLS2_k127_5078788_2 Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) K00209 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.44,1.3.1.9 0.0000000000000000000000000001274 119.0
TLS2_k127_5078788_3 SpoVT / AbrB like domain - - - 0.00000000000004339 75.0
TLS2_k127_5078788_4 HAD-hyrolase-like K07025 - - 0.00000000002042 64.0
TLS2_k127_5086065_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000005531 209.0
TLS2_k127_5086065_1 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000001165 202.0
TLS2_k127_5086065_2 Protein of unknown function (DUF2934) - - - 0.0000000000000000557 89.0
TLS2_k127_5086065_3 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000004751 54.0
TLS2_k127_508687_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.115e-213 674.0
TLS2_k127_508687_1 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000002217 224.0
TLS2_k127_508687_2 positive regulation of growth K01081 - 3.1.3.5 0.0000000000000000000001012 104.0
TLS2_k127_508687_3 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.00000000002726 66.0
TLS2_k127_5094340_0 response to abiotic stimulus K03086,K06867,K06886 - - 1.983e-237 750.0
TLS2_k127_5094340_1 response to abiotic stimulus K03086,K06867,K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 538.0
TLS2_k127_509854_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 605.0
TLS2_k127_509854_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006598 251.0
TLS2_k127_509854_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000006085 193.0
TLS2_k127_50986_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1404.0
TLS2_k127_50986_1 Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 572.0
TLS2_k127_50986_10 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0007461 50.0
TLS2_k127_50986_2 HlyD family secretion protein K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 380.0
TLS2_k127_50986_3 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000003473 186.0
TLS2_k127_50986_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000000000005861 168.0
TLS2_k127_50986_5 Disulphide bond corrector protein DsbC - - - 0.000000000000000000000000003708 117.0
TLS2_k127_50986_6 virion core protein, lumpy skin disease virus - - - 0.0000000000000000000001368 106.0
TLS2_k127_50986_7 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000411 99.0
TLS2_k127_50986_8 - - - - 0.0000000001229 67.0
TLS2_k127_50986_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000009989 53.0
TLS2_k127_5111370_0 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 565.0
TLS2_k127_5111370_1 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 486.0
TLS2_k127_5111370_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 405.0
TLS2_k127_5111370_3 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000003103 191.0
TLS2_k127_5111370_4 - - - - 0.000000000000000000000000000000000000001653 150.0
TLS2_k127_5111370_5 Initiation factor 2 subunit family K03680 - - 0.0000000000000000002781 98.0
TLS2_k127_5115068_0 amidohydrolase K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 592.0
TLS2_k127_5115068_1 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000002066 131.0
TLS2_k127_5115068_2 - - - - 0.00000000002717 66.0
TLS2_k127_5116126_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 303.0
TLS2_k127_5116126_1 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000002569 247.0
TLS2_k127_5116126_2 Protein phosphatase 2C K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000002022 199.0
TLS2_k127_5126522_0 anaphase-promoting complex binding - - - 0.0 1081.0
TLS2_k127_5126522_1 anaphase-promoting complex binding - - - 1.034e-206 665.0
TLS2_k127_5126522_2 anaphase-promoting complex binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 566.0
TLS2_k127_5126522_3 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 499.0
TLS2_k127_5126522_4 MacB-like periplasmic core domain - - - 0.0000000000000000000000004165 109.0
TLS2_k127_5128550_0 PQQ-like domain K00117 - 1.1.5.2 3.395e-313 977.0
TLS2_k127_5128550_1 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 337.0
TLS2_k127_5128550_2 Bacterial transcriptional regulator K13641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 297.0
TLS2_k127_5128550_3 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 269.0
TLS2_k127_5128550_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000001764 237.0
TLS2_k127_5135998_0 methyltransferase activity K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 345.0
TLS2_k127_5135998_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000001931 60.0
TLS2_k127_5137726_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 1.514e-203 645.0
TLS2_k127_5137726_1 Belongs to the xylose isomerase family K01805 - 5.3.1.5 5.884e-196 616.0
TLS2_k127_5137726_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000416 183.0
TLS2_k127_5151313_0 lipopolysaccharide transport K22110 - - 1.478e-241 752.0
TLS2_k127_5151313_1 Carboxypeptidase regulatory-like domain - - - 9.444e-221 702.0
TLS2_k127_5151313_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 414.0
TLS2_k127_5151313_3 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 336.0
TLS2_k127_5151313_4 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008279 246.0
TLS2_k127_5157180_0 unsaturated chondroitin disaccharide hydrolase activity K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 479.0
TLS2_k127_5157180_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 425.0
TLS2_k127_5157180_2 AAA domain, putative AbiEii toxin, Type IV TA system K06926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 403.0
TLS2_k127_5157180_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 297.0
TLS2_k127_5157180_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001611 283.0
TLS2_k127_5157180_5 RloB-like protein - - - 0.000000000000000633 81.0
TLS2_k127_5157723_0 choline dehydrogenase activity - - - 5.849e-272 844.0
TLS2_k127_5157723_1 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 283.0
TLS2_k127_5157723_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000005583 89.0
TLS2_k127_5158441_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 1.737e-214 675.0
TLS2_k127_5158441_1 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 552.0
TLS2_k127_5158441_10 Hydrolase Family 16 - - - 0.000000000002951 72.0
TLS2_k127_5158441_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 327.0
TLS2_k127_5158441_3 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002988 280.0
TLS2_k127_5158441_4 This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000232 276.0
TLS2_k127_5158441_5 Cytochrome P460 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004203 250.0
TLS2_k127_5158441_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002454 236.0
TLS2_k127_5158441_7 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000008846 208.0
TLS2_k127_5158441_8 Protein of unknown function, DUF417 - - - 0.00000000000000000000000000000000000000000000000005814 185.0
TLS2_k127_5158441_9 divalent heavy-metal cations transporter K07238 - - 0.0000000000000000000000000000000000000009887 158.0
TLS2_k127_5169633_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 352.0
TLS2_k127_5169633_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 282.0
TLS2_k127_5169633_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001718 287.0
TLS2_k127_5169633_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000001378 196.0
TLS2_k127_5169633_4 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000005316 179.0
TLS2_k127_5169633_5 ATP synthase F(0) sector subunit b K02109 - - 0.00000000000000000000006497 104.0
TLS2_k127_5169633_6 DNA-templated transcription, initiation - - - 0.000000000000003834 85.0
TLS2_k127_5169633_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000005176 67.0
TLS2_k127_5169633_8 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0007219 46.0
TLS2_k127_5178276_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 619.0
TLS2_k127_5178276_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 545.0
TLS2_k127_5178276_2 Peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 360.0
TLS2_k127_5178276_3 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000002808 163.0
TLS2_k127_5178276_4 PFAM oxidoreductase domain protein - - - 0.0000000000000000001416 92.0
TLS2_k127_5214537_0 PIN domain - - - 0.00000000000000000000000000000000224 134.0
TLS2_k127_5214537_1 - - - - 0.0000004346 54.0
TLS2_k127_5214537_2 - - - - 0.000005494 58.0
TLS2_k127_5252577_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 544.0
TLS2_k127_5252577_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 434.0
TLS2_k127_5252577_2 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.0000000000000000000000000000000000000000002729 163.0
TLS2_k127_5252577_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000003401 75.0
TLS2_k127_529224_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 325.0
TLS2_k127_5312047_0 Carboxypeptidase regulatory-like domain - - - 0.0 1189.0
TLS2_k127_5312047_1 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 390.0
TLS2_k127_5312047_2 FCD - - - 0.000000000000000000000000000000000000000000005366 173.0
TLS2_k127_5318839_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 551.0
TLS2_k127_5330993_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003509 256.0
TLS2_k127_5330993_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000002757 71.0
TLS2_k127_5330993_2 deoxyhypusine monooxygenase activity - - - 0.00000003455 59.0
TLS2_k127_5348821_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 3.978e-202 638.0
TLS2_k127_5348821_1 Methyltransferase small domain K00598 - 2.1.1.144 0.000000001675 63.0
TLS2_k127_5348821_2 hydrolase activity, acting on ester bonds - - - 0.000000002643 63.0
TLS2_k127_5352054_0 Protein of unknown function (DUF1501) - - - 6.452e-203 642.0
TLS2_k127_5352054_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 303.0
TLS2_k127_5367701_0 COG2382 Enterochelin esterase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 462.0
TLS2_k127_5367701_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000002258 138.0
TLS2_k127_5367701_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000005653 137.0
TLS2_k127_5404841_0 PQQ enzyme repeat K00117 - 1.1.5.2 3.248e-232 741.0
TLS2_k127_5404841_1 PQQ enzyme repeat K00117 - 1.1.5.2 2.908e-231 738.0
TLS2_k127_5404841_10 Trehalose utilisation - - - 0.000000000000000000000000000000000000001445 168.0
TLS2_k127_5404841_11 - - - - 0.000000000000000000000000000000000002576 140.0
TLS2_k127_5404841_12 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000004054 119.0
TLS2_k127_5404841_13 PFAM Xylose - - - 0.000000000000000000001321 110.0
TLS2_k127_5404841_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 446.0
TLS2_k127_5404841_3 arylformamidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 364.0
TLS2_k127_5404841_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 358.0
TLS2_k127_5404841_5 PFAM cyclase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 355.0
TLS2_k127_5404841_6 Bacterial transcriptional regulator K13641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 308.0
TLS2_k127_5404841_7 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000001017 275.0
TLS2_k127_5404841_8 KR domain K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000005833 248.0
TLS2_k127_5404841_9 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000005884 175.0
TLS2_k127_5407324_0 Membrane-bound dehydrogenase domain - - - 2.573e-252 810.0
TLS2_k127_5407324_1 Beta-lactamase - - - 2.307e-220 704.0
TLS2_k127_5407324_2 COG3119 Arylsulfatase A K01137 - 3.1.6.14 8.973e-203 646.0
TLS2_k127_5407324_3 COG3119 Arylsulfatase A K01138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 511.0
TLS2_k127_5407324_4 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009351 491.0
TLS2_k127_5407324_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 360.0
TLS2_k127_5407324_6 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000008248 200.0
TLS2_k127_5407324_7 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K18983 - 5.5.1.27 0.000002974 56.0
TLS2_k127_5418746_0 MacB-like periplasmic core domain - - - 5.518e-222 717.0
TLS2_k127_5418746_1 transcriptional regulator PadR family - - - 0.00000000000000000000000000000000000000000000000000001341 190.0
TLS2_k127_5418746_2 Sulfatase - - - 0.0000000000000000000000004376 109.0
TLS2_k127_5418746_3 COG3119 Arylsulfatase A - - - 0.0000000006005 64.0
TLS2_k127_5441304_0 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 403.0
TLS2_k127_5441304_1 - - - - 0.00000000000000000000000000000000007622 149.0
TLS2_k127_5447609_0 - - - - 6.572e-245 772.0
TLS2_k127_5447609_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 328.0
TLS2_k127_545479_0 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 351.0
TLS2_k127_545479_1 Protein of unknown function (DUF507) K09804 - - 0.000000000000000000000000000009996 121.0
TLS2_k127_5473910_0 Amidohydrolase family - - - 6.76e-239 751.0
TLS2_k127_5473910_1 PFAM Sodium alanine symporter family K03310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 545.0
TLS2_k127_5473910_2 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000008967 214.0
TLS2_k127_551823_0 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 490.0
TLS2_k127_551823_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000002956 194.0
TLS2_k127_551823_2 DinB superfamily - - - 0.00000000000000000000000001282 119.0
TLS2_k127_55231_0 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000005438 226.0
TLS2_k127_55231_1 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000000000000000000000000000000001929 208.0
TLS2_k127_55231_2 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.00000000000000000000000000000000000000000000000000009809 194.0
TLS2_k127_55231_3 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000004587 127.0
TLS2_k127_55231_4 Putative zinc-finger - - - 0.000000000000000000003737 94.0
TLS2_k127_5525261_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 598.0
TLS2_k127_5525261_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 298.0
TLS2_k127_5567248_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001066 260.0
TLS2_k127_5570700_0 Heat shock 70 kDa protein K04043 - - 1.746e-266 834.0
TLS2_k127_5570700_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 448.0
TLS2_k127_5570700_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 381.0
TLS2_k127_5570700_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000005365 256.0
TLS2_k127_5570700_4 PFAM thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000009574 193.0
TLS2_k127_5570700_5 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000000000000001128 152.0
TLS2_k127_5570700_7 ABC-2 family transporter protein K01992 - - 0.000000000000003925 78.0
TLS2_k127_55790_0 efflux transmembrane transporter activity - - - 0.0 1324.0
TLS2_k127_55790_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 612.0
TLS2_k127_55790_2 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000000000000000005181 198.0
TLS2_k127_55790_3 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000004335 193.0
TLS2_k127_5579213_0 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000001292 205.0
TLS2_k127_5579213_1 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000001045 73.0
TLS2_k127_5579213_2 PFAM Glycoside hydrolase, family 20, catalytic core K12373 - 3.2.1.52 0.000002736 60.0
TLS2_k127_5610679_0 Glycosyl hydrolases family 2, TIM barrel domain - - - 1.695e-219 696.0
TLS2_k127_5610679_1 alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 0.000000000000000000000000000000000003687 144.0
TLS2_k127_5610679_2 Pfam:Zinicin_2 - - - 0.00000000000000007252 85.0
TLS2_k127_5612637_0 Na H antiporter K05565 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 436.0
TLS2_k127_5612695_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 298.0
TLS2_k127_5612695_1 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004671 271.0
TLS2_k127_5612695_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000141 218.0
TLS2_k127_5612695_3 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000005308 209.0
TLS2_k127_5612695_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000001082 203.0
TLS2_k127_5612695_5 peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000005033 99.0
TLS2_k127_5612695_6 converts alpha-aldose to the beta-anomer - - - 0.00000000000000002356 83.0
TLS2_k127_5614095_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 523.0
TLS2_k127_5614095_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000004398 76.0
TLS2_k127_5615110_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0 1148.0
TLS2_k127_5615110_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 2.117e-222 696.0
TLS2_k127_5615110_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 1.546e-211 659.0
TLS2_k127_5615110_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 501.0
TLS2_k127_5615110_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 323.0
TLS2_k127_5615110_5 2 iron, 2 sulfur cluster binding K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000485 228.0
TLS2_k127_5615110_6 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000000000001184 195.0
TLS2_k127_5616443_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 370.0
TLS2_k127_5616443_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 294.0
TLS2_k127_5616443_2 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000001459 131.0
TLS2_k127_5616443_3 Helix-turn-helix domain K15539 - - 0.000000000000000000001591 107.0
TLS2_k127_5617569_0 cellulose binding - - - 6.554e-231 717.0
TLS2_k127_5617569_1 Belongs to the sigma-70 factor family. ECF subfamily - - - 1.951e-213 668.0
TLS2_k127_5617569_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000003261 97.0
TLS2_k127_5617569_2 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001002 238.0
TLS2_k127_5617569_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000004845 223.0
TLS2_k127_5617569_4 Glyoxalase-like domain K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000008704 222.0
TLS2_k127_5617569_5 Protein of unknown function (DUF1428) - - - 0.00000000000000000000000000000000000000000000000002855 181.0
TLS2_k127_5617569_6 - - - - 0.00000000000000000000000000000000000000000001077 168.0
TLS2_k127_5617569_7 YCII-related domain - - - 0.00000000000000000000000000000000000000000005802 162.0
TLS2_k127_5617569_8 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000007807 159.0
TLS2_k127_5617569_9 DinB superfamily - - - 0.0000000000000000000000000000000009642 138.0
TLS2_k127_5620834_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 634.0
TLS2_k127_5620834_1 amino acid carrier protein K03310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 512.0
TLS2_k127_5620834_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000004866 72.0
TLS2_k127_5620834_12 Protein of unknown function (DUF416) K09891 - - 0.00000000001826 73.0
TLS2_k127_5620834_13 self proteolysis - - - 0.000004529 52.0
TLS2_k127_5620834_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 443.0
TLS2_k127_5620834_3 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 390.0
TLS2_k127_5620834_4 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 359.0
TLS2_k127_5620834_5 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007631 277.0
TLS2_k127_5620834_6 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000007433 209.0
TLS2_k127_5620834_7 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000001857 175.0
TLS2_k127_5620834_8 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000002042 179.0
TLS2_k127_5620834_9 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000001767 170.0
TLS2_k127_5625101_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 623.0
TLS2_k127_5625101_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 494.0
TLS2_k127_5625101_2 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000000000000000001515 221.0
TLS2_k127_5625101_3 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000004558 138.0
TLS2_k127_5625101_4 Large extracellular alpha-helical protein K12548,K13735 - - 0.00005604 53.0
TLS2_k127_5625530_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1358.0
TLS2_k127_5625530_1 arylsulfatase activity K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 505.0
TLS2_k127_5625530_2 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 324.0
TLS2_k127_5625530_3 transmembrane transporter activity K03535,K08194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 301.0
TLS2_k127_5625530_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 297.0
TLS2_k127_5625530_5 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000006124 151.0
TLS2_k127_5627167_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1278.0
TLS2_k127_5627167_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 358.0
TLS2_k127_5627167_2 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 356.0
TLS2_k127_5627167_3 - - - - 0.0000000000000000000000000000000000000004996 162.0
TLS2_k127_5627233_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 3.111e-304 947.0
TLS2_k127_5627233_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 530.0
TLS2_k127_5627233_2 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003261 268.0
TLS2_k127_5632952_0 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003914 274.0
TLS2_k127_5632952_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000002181 224.0
TLS2_k127_5633914_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 339.0
TLS2_k127_5633914_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000001033 231.0
TLS2_k127_5633914_2 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000003381 226.0
TLS2_k127_5633914_3 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0000000000001016 75.0
TLS2_k127_5635208_0 secondary active sulfate transmembrane transporter activity K03321 GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 608.0
TLS2_k127_5635208_1 COG1012 NAD-dependent aldehyde - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 579.0
TLS2_k127_5635208_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000003547 66.0
TLS2_k127_5635208_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 581.0
TLS2_k127_5635208_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 545.0
TLS2_k127_5635208_4 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 534.0
TLS2_k127_5635208_5 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 522.0
TLS2_k127_5635208_6 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000944 518.0
TLS2_k127_5635208_7 NAD dependent epimerase/dehydratase family K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 481.0
TLS2_k127_5635208_8 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 304.0
TLS2_k127_5635208_9 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000000000003487 138.0
TLS2_k127_5644101_0 Glutamine synthetase type III K01915 - 6.3.1.2 5.229e-314 976.0
TLS2_k127_5644101_1 glutamine synthetase K01915 - 6.3.1.2 3.553e-249 777.0
TLS2_k127_5644101_10 TIGRFAM Flp pilus assembly protein CpaB K02279 - - 0.0000000000000000000005682 107.0
TLS2_k127_5644101_2 Carbamoyltransferase C-terminus K00612 - - 4.874e-196 626.0
TLS2_k127_5644101_3 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 510.0
TLS2_k127_5644101_4 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001431 273.0
TLS2_k127_5644101_5 type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000000001454 214.0
TLS2_k127_5644101_6 type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000001365 188.0
TLS2_k127_5644101_7 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000008687 183.0
TLS2_k127_5644101_8 PHP domain protein - - - 0.00000000000000000000000000000000000000000003561 180.0
TLS2_k127_5644101_9 Tetratricopeptide repeat - - - 0.000000000000000000000000009619 112.0
TLS2_k127_5649916_0 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 521.0
TLS2_k127_5649916_1 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 504.0
TLS2_k127_5650818_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.451e-233 734.0
TLS2_k127_5650818_1 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 541.0
TLS2_k127_5650818_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 321.0
TLS2_k127_5650818_3 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004929 276.0
TLS2_k127_5650818_4 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000004143 286.0
TLS2_k127_5650818_5 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000021 246.0
TLS2_k127_5650818_6 Beta-lactamase superfamily domain K06897 - 2.5.1.105 0.0000000000004649 74.0
TLS2_k127_5654799_0 PQQ-like domain K00114 - 1.1.2.8 5.884e-198 632.0
TLS2_k127_5654799_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 616.0
TLS2_k127_5654799_10 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.0000000000000000000000000007722 120.0
TLS2_k127_5654799_2 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 479.0
TLS2_k127_5654799_3 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 351.0
TLS2_k127_5654799_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001091 239.0
TLS2_k127_5654799_5 RNA-DNA hybrid ribonuclease activity K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000002124 219.0
TLS2_k127_5654799_6 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000003454 220.0
TLS2_k127_5654799_7 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000005471 205.0
TLS2_k127_5654799_8 Cytochrome c - - - 0.0000000000000000000000000000000000000000000002587 178.0
TLS2_k127_5654799_9 transcription regulator containing HTH domain K18831 - - 0.00000000000000000000000000001659 124.0
TLS2_k127_5668154_0 TonB dependent receptor - - - 2.483e-247 784.0
TLS2_k127_5668154_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 420.0
TLS2_k127_5668154_2 COG0168 Trk-type K transport systems, membrane components K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 420.0
TLS2_k127_5668154_3 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 408.0
TLS2_k127_5668154_4 SMP-30 Gluconolaconase K14274 - - 0.0000000000000000000000000000000000000000000000000000000000004841 218.0
TLS2_k127_5668154_5 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000001045 191.0
TLS2_k127_5668154_6 - - - - 0.000000000000000000000000000000000000000009973 171.0
TLS2_k127_5668154_7 response regulator - - - 0.000000000000000000000000000000000000003168 154.0
TLS2_k127_5668154_9 YtxH-like protein - - - 0.00000000000000000001453 94.0
TLS2_k127_5668925_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 523.0
TLS2_k127_5668925_1 H( )-stimulated, divalent metal cation uptake system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 386.0
TLS2_k127_5668925_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 293.0
TLS2_k127_5668925_3 efflux transmembrane transporter activity - - - 0.00000000000000009628 85.0
TLS2_k127_5686968_0 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 1.025e-251 807.0
TLS2_k127_5686968_1 PFAM Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 361.0
TLS2_k127_5686968_2 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 347.0
TLS2_k127_5686968_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K08641,K11206 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 332.0
TLS2_k127_5686968_4 NUBPL iron-transfer P-loop NTPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002886 241.0
TLS2_k127_5686968_5 (FHA) domain - - - 0.00000002762 63.0
TLS2_k127_5687899_0 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 602.0
TLS2_k127_5687899_1 nuclear-transcribed mRNA catabolic process, no-go decay - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 468.0
TLS2_k127_5687899_10 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000000000000002161 147.0
TLS2_k127_5687899_11 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000007001 145.0
TLS2_k127_5687899_12 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000000000006005 137.0
TLS2_k127_5687899_13 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000001478 133.0
TLS2_k127_5687899_14 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K05559,K05565 GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.0000000000000000972 80.0
TLS2_k127_5687899_15 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.00000000000131 71.0
TLS2_k127_5687899_2 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 359.0
TLS2_k127_5687899_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000001998 222.0
TLS2_k127_5687899_5 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000000000000001016 184.0
TLS2_k127_5687899_6 Na+/H+ ion antiporter subunit K05569 - - 0.000000000000000000000000000000000000000000000002995 186.0
TLS2_k127_5687899_7 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000003576 163.0
TLS2_k127_5687899_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000002529 162.0
TLS2_k127_5687899_9 Na H antiporter, MnhB K05566 - - 0.000000000000000000000000000000000000008724 150.0
TLS2_k127_5688572_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 361.0
TLS2_k127_5688572_1 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 353.0
TLS2_k127_5689544_0 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 304.0
TLS2_k127_5689544_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004388 279.0
TLS2_k127_5692848_1 Cytochrome c - - - 0.000000000000000000000000000002059 123.0
TLS2_k127_5697089_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 491.0
TLS2_k127_5697089_1 Protein of unknown function (DUF1553) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 349.0
TLS2_k127_5703199_0 PFAM glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 471.0
TLS2_k127_5703199_1 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 374.0
TLS2_k127_5703199_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000004018 160.0
TLS2_k127_5703199_3 Transposase IS200 like K07491 - - 0.000000001414 65.0
TLS2_k127_5706739_0 Putative transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 507.0
TLS2_k127_5706739_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 521.0
TLS2_k127_5706739_2 phage integrase domain protein SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 346.0
TLS2_k127_5706739_3 - - - - 0.0000000000000000000000000000000000000002474 156.0
TLS2_k127_5706739_4 cAMP biosynthetic process - - - 0.00000000000000000000000000000000002749 141.0
TLS2_k127_5706739_6 Phage integrase family - - - 0.00002698 52.0
TLS2_k127_5708972_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 345.0
TLS2_k127_5708972_1 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000005694 139.0
TLS2_k127_5708972_2 Multidrug Resistance protein - - - 0.00000000000000000000000000008526 120.0
TLS2_k127_5708972_3 Small Multidrug Resistance protein - - - 0.0000000000000000000000000004278 122.0
TLS2_k127_5708972_4 Serine threonine protein kinase K08282 - 2.7.11.1 0.00002086 53.0
TLS2_k127_5710655_0 Cytochrome C - - - 1.286e-247 790.0
TLS2_k127_5710655_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.26e-200 631.0
TLS2_k127_5710655_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008106 575.0
TLS2_k127_5710655_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 396.0
TLS2_k127_5710655_4 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008286 302.0
TLS2_k127_5714581_0 Aminotransferase class I and II K14261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 603.0
TLS2_k127_5714581_1 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 565.0
TLS2_k127_5714581_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 510.0
TLS2_k127_5714581_3 gluconolactonase K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 468.0
TLS2_k127_5714581_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 343.0
TLS2_k127_5714581_5 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000002073 116.0
TLS2_k127_5717570_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 494.0
TLS2_k127_5717570_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000003458 214.0
TLS2_k127_5717570_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000007408 187.0
TLS2_k127_5717570_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000003928 124.0
TLS2_k127_5717570_4 Phosphogluconate dehydrogenase (decarboxylating) C-term - - - 0.0000000000000000007337 87.0
TLS2_k127_571915_0 Carboxypeptidase regulatory-like domain - - - 9.565e-214 703.0
TLS2_k127_571915_1 4-phosphoerythronate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 378.0
TLS2_k127_571915_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004467 249.0
TLS2_k127_571915_3 Malate/L-lactate dehydrogenase K13574 - - 0.00000000000000000000000000000000000000000000000000000000000000000006708 244.0
TLS2_k127_571915_4 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000005143 197.0
TLS2_k127_571915_5 Aldolase/RraA K10218 - 4.1.3.17 0.000000000000000000008892 102.0
TLS2_k127_571915_6 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000003163 63.0
TLS2_k127_571915_7 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00090 - 1.1.1.215,1.1.1.79,1.1.1.81 0.0003254 48.0
TLS2_k127_5724284_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 390.0
TLS2_k127_5724284_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 349.0
TLS2_k127_5724284_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001695 282.0
TLS2_k127_5724284_3 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000761 139.0
TLS2_k127_5724284_4 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000002304 132.0
TLS2_k127_5724284_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000005956 57.0
TLS2_k127_5726373_0 diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 646.0
TLS2_k127_5726373_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000001078 132.0
TLS2_k127_5726373_2 Polymer-forming cytoskeletal - - - 0.000000008784 67.0
TLS2_k127_5728658_0 -O-antigen K02847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 353.0
TLS2_k127_5728658_1 phage Terminase large subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000398 265.0
TLS2_k127_5728658_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000004003 216.0
TLS2_k127_5728658_3 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K20997 - - 0.000000000000000000000000000000000000000000000000001769 191.0
TLS2_k127_5728658_4 phospholipase C - - - 0.0000000007649 70.0
TLS2_k127_5732296_0 PQQ-like domain K00114 - 1.1.2.8 5.065e-216 683.0
TLS2_k127_5732296_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01707 - 4.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 346.0
TLS2_k127_5732296_2 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 325.0
TLS2_k127_5732296_3 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000225 259.0
TLS2_k127_5732296_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000002028 189.0
TLS2_k127_5732296_5 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000008257 144.0
TLS2_k127_5732296_6 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000009033 137.0
TLS2_k127_5736792_0 Putative collagen-binding domain of a collagenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 388.0
TLS2_k127_5736792_1 zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 340.0
TLS2_k127_5736792_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 295.0
TLS2_k127_5736792_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000001996 193.0
TLS2_k127_5736792_4 NIPSNAP family containing protein - - - 0.00000000000000000000000000000000000001625 150.0
TLS2_k127_5742227_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.538e-254 795.0
TLS2_k127_5742227_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 286.0
TLS2_k127_5742227_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000001566 128.0
TLS2_k127_5742227_3 cell adhesion involved in biofilm formation K01186 - 3.2.1.18 0.000000000000000000000000004768 128.0
TLS2_k127_5744806_0 efflux transmembrane transporter activity - - - 4.982e-274 871.0
TLS2_k127_5744806_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 557.0
TLS2_k127_5744806_2 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000948 277.0
TLS2_k127_5744806_3 L-rhamnose mutarotase K03534 - 5.1.3.32 0.00000000000000000000000000000000000000000000124 171.0
TLS2_k127_5744806_4 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000001187 145.0
TLS2_k127_5745789_0 cellular response to dsDNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 314.0
TLS2_k127_5745789_1 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000002013 148.0
TLS2_k127_5745789_2 defense response to other organism K02395,K19220,K19223 GO:0005575,GO:0005576 - 0.0000000000000000000000000001196 123.0
TLS2_k127_5745789_3 Protein of unknown function (DUF3037) - - - 0.000001035 59.0
TLS2_k127_5745789_4 extracellular polysaccharide biosynthetic process K09690,K16554,K16692 - - 0.000007294 54.0
TLS2_k127_5745789_5 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0004226 45.0
TLS2_k127_5769092_0 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 544.0
TLS2_k127_5769092_1 Belongs to the DapA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 442.0
TLS2_k127_5769092_2 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 400.0
TLS2_k127_5769092_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 304.0
TLS2_k127_5769092_4 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002409 281.0
TLS2_k127_5769092_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005812 235.0
TLS2_k127_5769092_6 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000008163 218.0
TLS2_k127_5769092_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000001905 162.0
TLS2_k127_5769092_9 - - - - 0.0000000000000000001182 93.0
TLS2_k127_5769107_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 357.0
TLS2_k127_5769107_1 transferase activity, transferring glycosyl groups K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 329.0
TLS2_k127_5769107_2 peptidase activity K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000004546 276.0
TLS2_k127_5769107_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000001574 196.0
TLS2_k127_577524_0 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 426.0
TLS2_k127_577524_1 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 354.0
TLS2_k127_577524_2 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001221 266.0
TLS2_k127_577524_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006908 243.0
TLS2_k127_577524_4 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000001514 205.0
TLS2_k127_577524_5 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000005057 157.0
TLS2_k127_5778395_0 His Kinase A (phosphoacceptor) domain - - - 3.484e-195 655.0
TLS2_k127_5778395_1 Resolvase, N terminal domain - - - 0.000000000000000000000000002537 116.0
TLS2_k127_5782386_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 418.0
TLS2_k127_5782386_1 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784,K13318,K13322,K16439,K19857 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 310.0
TLS2_k127_5782386_2 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005282 271.0
TLS2_k127_5782386_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000002779 204.0
TLS2_k127_5788145_0 ABC transporter (Permease K01992 - - 0.000000000000000000000000000000000000000000000000000000000000001699 226.0
TLS2_k127_5788145_1 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000002113 62.0
TLS2_k127_5788155_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003394 280.0
TLS2_k127_5788155_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000008799 232.0
TLS2_k127_5788155_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000004017 118.0
TLS2_k127_5791547_0 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 319.0
TLS2_k127_5791547_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001165 244.0
TLS2_k127_5791547_2 PIN domain - - - 0.0000000000000000001439 93.0
TLS2_k127_5791547_3 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000424 61.0
TLS2_k127_5791547_4 SpoVT / AbrB like domain - - - 0.000001347 53.0
TLS2_k127_5796352_0 -O-antigen K02847,K13009 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 365.0
TLS2_k127_5796352_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002369 285.0
TLS2_k127_5796609_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000003158 231.0
TLS2_k127_5796609_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000007137 219.0
TLS2_k127_579857_0 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 290.0
TLS2_k127_579857_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000005555 196.0
TLS2_k127_579857_2 lysyltransferase activity K07027,K20468 - - 0.000000000000000000000000000007322 131.0
TLS2_k127_579857_3 von Willebrand factor type A domain - - - 0.0002198 51.0
TLS2_k127_5799885_0 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 499.0
TLS2_k127_5799885_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 451.0
TLS2_k127_5799885_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003141 274.0
TLS2_k127_5799885_3 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000002073 226.0
TLS2_k127_5803259_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 368.0
TLS2_k127_5803259_1 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000001703 234.0
TLS2_k127_5803259_2 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000000000000000000000000000000009084 196.0
TLS2_k127_5803259_3 glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000209 194.0
TLS2_k127_5803259_4 SnoaL-like domain K06893 - - 0.00000000000000000000000000003093 122.0
TLS2_k127_5803259_5 - - - - 0.000000000000000000000000002056 118.0
TLS2_k127_5809786_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 3.774e-218 698.0
TLS2_k127_5809786_1 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006964 258.0
TLS2_k127_5809786_2 2 iron, 2 sulfur cluster binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000001251 236.0
TLS2_k127_5814649_0 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 492.0
TLS2_k127_5814649_1 metallopeptidase activity K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000002206 235.0
TLS2_k127_5814649_2 PFAM thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000009105 149.0
TLS2_k127_5829128_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 294.0
TLS2_k127_5829128_1 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 289.0
TLS2_k127_5829128_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001907 284.0
TLS2_k127_5843404_0 - - - - 0.000000000000000000000000000000000000000000001321 170.0
TLS2_k127_5843404_1 Domain of unknown function (DUF368) K08974 - - 0.000000000000000000000000002181 124.0
TLS2_k127_5843404_2 K -dependent Na Ca exchanger K07301 - - 0.00000000001523 70.0
TLS2_k127_5859605_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1616.0
TLS2_k127_5859605_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 403.0
TLS2_k127_5859605_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 400.0
TLS2_k127_5859605_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 354.0
TLS2_k127_5859605_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000009582 252.0
TLS2_k127_5859605_5 CYTH K05873 - 4.6.1.1 0.0000000000000000000000000000000000000004635 156.0
TLS2_k127_5859605_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) - - - 0.0000000000000000000000000000000000008742 141.0
TLS2_k127_5865188_1 Belongs to the bacterial flagellin family K02397 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000005591 64.0
TLS2_k127_5878927_0 Two component regulator three Y - - - 0.0 1225.0
TLS2_k127_5878927_1 Carboxypeptidase regulatory-like domain - - - 0.0 1221.0
TLS2_k127_5878927_2 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 594.0
TLS2_k127_5878927_3 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 337.0
TLS2_k127_5878927_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 315.0
TLS2_k127_5878927_5 DNA binding domain with preference for A/T rich regions K07491 - - 0.0000000000000000000000000000000000000000000000000000002002 202.0
TLS2_k127_5878927_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000007536 187.0
TLS2_k127_5886728_0 protocatechuate 3,4-dioxygenase activity - - - 0.0 1212.0
TLS2_k127_5886728_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000002627 222.0
TLS2_k127_5886728_2 Enoyl-(Acyl carrier protein) reductase K18009 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000002358 192.0
TLS2_k127_5886728_3 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000001185 169.0
TLS2_k127_5886728_4 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000005725 92.0
TLS2_k127_5886728_5 - - - - 0.0000000000364 67.0
TLS2_k127_5903095_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 1.76e-196 624.0
TLS2_k127_5903095_1 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 475.0
TLS2_k127_5903095_2 - - - - 0.0000000000000000009058 88.0
TLS2_k127_5904572_0 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 351.0
TLS2_k127_5904572_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 354.0
TLS2_k127_5904572_3 Domain of unknown function (DUF2341) - - - 0.0000000000000000000000006563 114.0
TLS2_k127_5904572_4 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000008844 82.0
TLS2_k127_5904572_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000001079 63.0
TLS2_k127_5906259_0 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009268 277.0
TLS2_k127_5906259_1 Outer membrane protein beta-barrel family - - - 0.0000000000000001258 84.0
TLS2_k127_5906259_2 Peptidase m28 - - - 0.0003415 46.0
TLS2_k127_5932201_0 GMC oxidoreductase - - - 1.995e-234 737.0
TLS2_k127_5932201_1 NikR C terminal nickel binding domain K07722 - - 0.000000000000000000000000000000000000000000000000000000000001688 213.0
TLS2_k127_5932201_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000001224 137.0
TLS2_k127_5932201_3 Adenylate cyclase - - - 0.0000000000000000000000001201 117.0
TLS2_k127_5940295_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 591.0
TLS2_k127_5940295_1 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000000000000523 142.0
TLS2_k127_5940295_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00002609 49.0
TLS2_k127_5971798_0 MacB-like periplasmic core domain - - - 6.141e-310 971.0
TLS2_k127_5971798_1 elongation factor Tu domain 2 protein K02355 - - 1.832e-221 708.0
TLS2_k127_5971798_2 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 331.0
TLS2_k127_6009376_0 MacB-like periplasmic core domain - - - 0.0 1371.0
TLS2_k127_6009376_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000004426 249.0
TLS2_k127_6009376_2 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000000000000000002679 192.0
TLS2_k127_6009376_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000005569 68.0
TLS2_k127_6017544_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 390.0
TLS2_k127_6017544_1 Domain of unknown function (DUF4440) - - - 0.0002075 48.0
TLS2_k127_6018189_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 4.091e-316 984.0
TLS2_k127_6018189_1 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000000000002014 132.0
TLS2_k127_604565_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 456.0
TLS2_k127_604565_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 443.0
TLS2_k127_604565_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 283.0
TLS2_k127_604565_3 - - - - 0.0000000000003941 80.0
TLS2_k127_6051547_0 amidase activity K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005692 282.0
TLS2_k127_6051547_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000001706 166.0
TLS2_k127_6058658_0 ASPIC and UnbV - - - 1.263e-237 747.0
TLS2_k127_6058658_1 Belongs to the aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 5.053e-235 736.0
TLS2_k127_6058658_2 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 303.0
TLS2_k127_6058658_3 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000002232 254.0
TLS2_k127_6058658_4 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000004671 219.0
TLS2_k127_6058658_5 membrane organization K07277 - - 0.0000000000000000000000000000000000000000000000000000000000001029 237.0
TLS2_k127_6058658_6 TIGRFAM methyltransferase FkbM - - - 0.0000000000004271 81.0
TLS2_k127_6058672_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 335.0
TLS2_k127_6058672_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000005443 169.0
TLS2_k127_6059430_0 PUA-like domain K00958,K13811 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 415.0
TLS2_k127_6059430_1 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003216 280.0
TLS2_k127_6059430_2 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000004898 270.0
TLS2_k127_6059430_3 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000003761 261.0
TLS2_k127_6059430_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000004267 240.0
TLS2_k127_6063997_0 ERAP1-like C-terminal domain K01263 - 3.4.11.14 2.822e-229 745.0
TLS2_k127_6063997_1 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 498.0
TLS2_k127_6063997_2 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 364.0
TLS2_k127_6063997_3 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 323.0
TLS2_k127_6063997_4 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000006867 206.0
TLS2_k127_6063997_5 - - - - 0.0000000000003217 77.0
TLS2_k127_6076807_0 WD40-like Beta Propeller K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 407.0
TLS2_k127_6076807_1 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001091 258.0
TLS2_k127_6076807_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.00000000000000000004696 90.0
TLS2_k127_6076807_3 Isochorismatase family - - - 0.0000000000000000002154 88.0
TLS2_k127_6076807_4 TIGRFAM tol-pal system protein YbgF - - - 0.00000000000004221 83.0
TLS2_k127_6076807_5 TIGRFAM TonB family K03832 - - 0.000000003588 59.0
TLS2_k127_6092757_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 377.0
TLS2_k127_6092757_1 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K10716 - - 0.000000000000000000000000000000000000000000000000000000000000002229 229.0
TLS2_k127_6092757_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000003951 64.0
TLS2_k127_6097107_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1213.0
TLS2_k127_6097107_1 efflux transmembrane transporter activity - - - 2.415e-202 660.0
TLS2_k127_6097107_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005864 267.0
TLS2_k127_6097107_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000009695 227.0
TLS2_k127_6097107_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000001564 226.0
TLS2_k127_6097107_5 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000000004113 206.0
TLS2_k127_6097107_6 Shikimate kinase K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000001181 174.0
TLS2_k127_6097107_7 ATP-dependent protease La (LON) substrate-binding domain - - - 0.00000000000000000000000000000000104 137.0
TLS2_k127_6099868_0 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 301.0
TLS2_k127_6099868_1 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000001849 233.0
TLS2_k127_6099868_2 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000000000000000000006936 123.0
TLS2_k127_6100492_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.927e-227 730.0
TLS2_k127_6100492_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.168e-217 686.0
TLS2_k127_6100492_10 Putative zinc-finger - - - 0.0000526 55.0
TLS2_k127_6100492_2 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 408.0
TLS2_k127_6100492_3 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 405.0
TLS2_k127_6100492_4 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 302.0
TLS2_k127_6100492_5 ROK family K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 294.0
TLS2_k127_6100492_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004469 262.0
TLS2_k127_6100492_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000009009 222.0
TLS2_k127_6100492_8 Bacterial regulatory proteins, luxR family K03088 - - 0.00000000000000000000000000000000000000000000000000000004058 200.0
TLS2_k127_6100492_9 - - - - 0.000000000000002413 80.0
TLS2_k127_6105887_0 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 439.0
TLS2_k127_6105887_1 COG0471 Di- and tricarboxylate transporters K14445 - - 0.000000000000000000000000000000000000000000005079 174.0
TLS2_k127_6107106_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.138e-240 764.0
TLS2_k127_6107106_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 575.0
TLS2_k127_6107106_2 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 360.0
TLS2_k127_6107106_3 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 319.0
TLS2_k127_6107106_4 - - - - 0.0000000000000000000004522 106.0
TLS2_k127_6107106_6 toxin-antitoxin pair type II binding - - - 0.00000000000000003644 83.0
TLS2_k127_6131256_0 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000359 178.0
TLS2_k127_6131256_1 Methyltransferase domain - - - 0.0000000000000000000001028 108.0
TLS2_k127_6131256_2 - - - - 0.0000000000000004311 84.0
TLS2_k127_6145908_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 326.0
TLS2_k127_6145908_1 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001425 286.0
TLS2_k127_6145908_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000003675 187.0
TLS2_k127_6145908_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000001502 158.0
TLS2_k127_615008_0 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000000002901 165.0
TLS2_k127_615008_1 domain protein K20276 - - 0.0000000000000009496 91.0
TLS2_k127_615008_2 Carboxypeptidase regulatory-like domain - - - 0.0000002392 61.0
TLS2_k127_6165787_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 518.0
TLS2_k127_6165787_1 Maf-like protein K06287 - - 0.00000000000000000000000000000009081 128.0
TLS2_k127_6165787_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000003405 108.0
TLS2_k127_6165787_3 Helix-turn-helix domain - - - 0.00000000000000000000000427 105.0
TLS2_k127_6165787_5 Protein of unknown function (DUF721) - - - 0.0002252 49.0
TLS2_k127_6210019_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 561.0
TLS2_k127_6210019_1 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 364.0
TLS2_k127_6210019_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000003651 201.0
TLS2_k127_623193_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.395e-199 630.0
TLS2_k127_623193_1 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 321.0
TLS2_k127_623193_2 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 300.0
TLS2_k127_623193_3 Transporter, CPA2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000004965 238.0
TLS2_k127_623193_4 Metalloenzyme superfamily - - - 0.000007244 58.0
TLS2_k127_623193_5 cobalamin-transporting ATPase activity K02014 - - 0.00007774 45.0
TLS2_k127_6236800_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 6.708e-223 711.0
TLS2_k127_6236800_1 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005123 277.0
TLS2_k127_6236800_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000009682 209.0
TLS2_k127_6236800_3 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000002603 163.0
TLS2_k127_6236800_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000002054 81.0
TLS2_k127_6236800_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000006341 83.0
TLS2_k127_6236800_6 acetyltransferase - - - 0.0000000000001493 83.0
TLS2_k127_6267382_0 Glutamate-ammonia ligase adenylyltransferase K00982 - 2.7.7.42,2.7.7.89 8.171e-242 781.0
TLS2_k127_627001_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.781e-196 631.0
TLS2_k127_627001_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 336.0
TLS2_k127_627001_2 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000009373 106.0
TLS2_k127_628001_0 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 480.0
TLS2_k127_628001_1 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 402.0
TLS2_k127_628001_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 310.0
TLS2_k127_628001_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002931 254.0
TLS2_k127_628001_4 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.0000000000000000000004948 98.0
TLS2_k127_628001_5 SnoaL-like domain - - - 0.000000000000000000001968 102.0
TLS2_k127_628001_6 RNA-directed DNA polymerase (reverse transcriptase) K00986 - 2.7.7.49 0.00000002001 59.0
TLS2_k127_6302830_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.603e-319 1019.0
TLS2_k127_6302830_1 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000000000000000000000005886 202.0
TLS2_k127_6302830_2 iron ion homeostasis - - - 0.0000000000000002304 88.0
TLS2_k127_6318314_0 Cytochrome c - - - 0.0 1131.0
TLS2_k127_6318314_1 long-chain fatty acid transporting porin activity - - - 6.642e-207 652.0
TLS2_k127_6318314_2 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001492 275.0
TLS2_k127_6318314_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001652 264.0
TLS2_k127_6359901_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 308.0
TLS2_k127_6359901_1 pyrroloquinoline quinone binding K12287 - - 0.00000000000000000000000000114 119.0
TLS2_k127_6359901_2 - - - - 0.0000000003937 61.0
TLS2_k127_6359901_3 Cell wall-active antibiotics response 4TMS YvqF - - - 0.000000007754 62.0
TLS2_k127_6432083_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1194.0
TLS2_k127_6432083_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 357.0
TLS2_k127_644515_0 glutamate synthase alpha subunit K00265 - 1.4.1.13,1.4.1.14 0.0 2047.0
TLS2_k127_644515_1 OsmC-like protein - - - 0.000000000000000000000000000000000000000000004745 169.0
TLS2_k127_644515_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000002574 128.0
TLS2_k127_644515_3 Insulinase (Peptidase family M16) K07263 - - 0.000001301 50.0
TLS2_k127_6499139_0 lipopolysaccharide transport K22110 - - 7.391e-213 669.0
TLS2_k127_6499139_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 332.0
TLS2_k127_6547737_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 510.0
TLS2_k127_6547737_1 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 374.0
TLS2_k127_6547737_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000002214 224.0
TLS2_k127_6550814_0 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 634.0
TLS2_k127_6550814_1 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 405.0
TLS2_k127_6550814_11 Tetratricopeptide repeat - - - 0.0000003846 60.0
TLS2_k127_6550814_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004713 258.0
TLS2_k127_6550814_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000009425 162.0
TLS2_k127_6550814_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000004013 149.0
TLS2_k127_6550814_5 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures - - - 0.00000000000000000000000000000000005673 147.0
TLS2_k127_6550814_6 response regulator K07657 - - 0.000000000000000000000000006536 115.0
TLS2_k127_6550814_7 CAAX protease self-immunity K07052,K09696 - - 0.00000000000000000000005045 110.0
TLS2_k127_6550814_8 - - - - 0.000000000000000000005526 106.0
TLS2_k127_6550814_9 helix_turn_helix, Lux Regulon - - - 0.000000000000002958 85.0
TLS2_k127_6554399_0 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000002426 246.0
TLS2_k127_6554399_1 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000232 252.0
TLS2_k127_6554399_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000002226 242.0
TLS2_k127_6559275_0 TonB-dependent receptor - - - 5.226e-303 957.0
TLS2_k127_6559275_1 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000001256 204.0
TLS2_k127_6560333_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 411.0
TLS2_k127_6560333_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 340.0
TLS2_k127_6560333_2 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 335.0
TLS2_k127_6560333_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 278.0
TLS2_k127_6560333_4 Radical SAM - - - 0.0000000000000000000000000000000000000000001325 162.0
TLS2_k127_6561_0 MacB-like periplasmic core domain - - - 0.0 1162.0
TLS2_k127_6561_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 554.0
TLS2_k127_6561_2 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000000000000001505 198.0
TLS2_k127_6561_3 - - - - 0.0000000000000000001225 98.0
TLS2_k127_6561538_0 PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 443.0
TLS2_k127_6561538_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 394.0
TLS2_k127_6561538_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000818 94.0
TLS2_k127_6561538_3 translocon at the outer membrane of chloroplasts 64-v - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0072655 - 0.00001694 53.0
TLS2_k127_6581402_0 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005715 272.0
TLS2_k127_6581402_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000002434 228.0
TLS2_k127_6581402_2 - - - - 0.000000000000000000000000000000000000000000001926 179.0
TLS2_k127_6582343_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 484.0
TLS2_k127_6582343_1 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 373.0
TLS2_k127_6582343_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 332.0
TLS2_k127_6582343_3 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00001349 47.0
TLS2_k127_6584007_0 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 528.0
TLS2_k127_6584007_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000792 246.0
TLS2_k127_6584007_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000001357 232.0
TLS2_k127_6584007_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000004374 129.0
TLS2_k127_6584007_4 META domain - - - 0.00000000001108 74.0
TLS2_k127_6588706_0 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 396.0
TLS2_k127_6588706_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 356.0
TLS2_k127_6588706_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 312.0
TLS2_k127_6588706_3 gas vesicle protein - - - 0.00000007408 57.0
TLS2_k127_6588933_0 Required for chromosome condensation and partitioning K03529 - - 1.569e-223 726.0
TLS2_k127_6594179_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 346.0
TLS2_k127_6599382_0 efflux transmembrane transporter activity - - - 1.812e-311 977.0
TLS2_k127_6599382_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 497.0
TLS2_k127_6599382_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000001113 194.0
TLS2_k127_6608398_0 Ribulose bisphosphate carboxylase large chain, N-terminal domain K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 571.0
TLS2_k127_6608398_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 519.0
TLS2_k127_6608398_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000006473 186.0
TLS2_k127_6608398_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000009166 179.0
TLS2_k127_6608398_4 Tetratricopeptide repeat - - - 0.00000000001924 75.0
TLS2_k127_6633124_0 lipopolysaccharide transport K22110 - - 2.676e-285 881.0
TLS2_k127_6633124_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 405.0
TLS2_k127_6633124_2 Glycogen debranching enzyme - - - 0.000000000000000000000004433 103.0
TLS2_k127_6637895_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00018 - 1.1.1.26,1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 396.0
TLS2_k127_6637895_1 3'(2'),5'-bisphosphate nucleotidase K01082 GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001275 270.0
TLS2_k127_6637895_11 Phage integrase family - - - 0.0000000009593 66.0
TLS2_k127_6637895_12 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000002064 57.0
TLS2_k127_6637895_13 Putative adhesin - - - 0.0000148 57.0
TLS2_k127_6637895_14 - - - - 0.00004649 48.0
TLS2_k127_6637895_2 LmbE homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002887 258.0
TLS2_k127_6637895_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000271 223.0
TLS2_k127_6637895_4 HEAT repeats - - - 0.00000000000000000000000000000000000000003706 165.0
TLS2_k127_6637895_5 SnoaL-like domain - - - 0.000000000000000000000000000000000000002841 149.0
TLS2_k127_6637895_7 Phage integrase family - - - 0.0000000000000000000000000000000000987 144.0
TLS2_k127_6646084_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.894e-258 806.0
TLS2_k127_6646084_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 4.063e-202 648.0
TLS2_k127_6646084_2 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004075 280.0
TLS2_k127_6646084_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000009088 150.0
TLS2_k127_6646084_4 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000622 138.0
TLS2_k127_6646084_5 Cold shock protein domain K03704 - - 0.00000000000000000000005368 106.0
TLS2_k127_6652373_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 557.0
TLS2_k127_6652373_1 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 379.0
TLS2_k127_6652373_10 PFAM CHAD domain containing protein - - - 0.00001821 53.0
TLS2_k127_6652373_3 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 287.0
TLS2_k127_6652373_4 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000001268 246.0
TLS2_k127_6652373_5 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000006382 216.0
TLS2_k127_6652373_6 6-phosphogluconolactonase glucosamine-6-phosphate isomerase deaminase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000001635 160.0
TLS2_k127_6652373_7 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000000000005181 98.0
TLS2_k127_6652373_8 - - - - 0.00000000000000001955 86.0
TLS2_k127_6652373_9 PFAM CHAD domain containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000004064 72.0
TLS2_k127_6654550_0 Protein of unknown function (DUF1501) - - - 6.857e-221 694.0
TLS2_k127_6654550_1 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 550.0
TLS2_k127_6654550_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000001631 190.0
TLS2_k127_6658771_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.899e-242 766.0
TLS2_k127_6658771_1 Sigma-70 region 3 K02405,K03093 - - 0.00000000000000000000000000000000000000000000000000000000000000000001076 241.0
TLS2_k127_6658771_2 membrane-bound metal-dependent hydrolase K07038 - - 0.00000000000000000000000000000000000000000000000000000000000000001676 236.0
TLS2_k127_6658771_3 Diacylglycerol kinase catalytic domain (presumed) - - - 0.000000000000000000000000000000000000000000000000002065 194.0
TLS2_k127_6658771_4 regulator - - - 0.00000000000000000007004 101.0
TLS2_k127_6660428_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 599.0
TLS2_k127_6660428_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 433.0
TLS2_k127_6660428_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 413.0
TLS2_k127_6660428_3 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 394.0
TLS2_k127_6660428_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000203 202.0
TLS2_k127_6660428_6 FRG - - - 0.00000000000000000001565 103.0
TLS2_k127_6660428_7 PFAM SMP-30 Gluconolaconase - - - 0.00002604 56.0
TLS2_k127_6672765_0 cobalamin-transporting ATPase activity K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004327 257.0
TLS2_k127_6672765_1 Zincin-like metallopeptidase - - - 0.000000000000000000000000006107 114.0
TLS2_k127_6672765_2 NAD-dependent epimerase dehydratase - - - 0.0000004889 54.0
TLS2_k127_6682326_0 PFAM peptidase M61 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003564 246.0
TLS2_k127_6682326_1 - - - - 0.00000003734 64.0
TLS2_k127_6683356_0 Pyridine nucleotide-disulphide oxidoreductase K00266,K00528,K17722 - 1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 388.0
TLS2_k127_6683356_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 392.0
TLS2_k127_6707521_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 322.0
TLS2_k127_6707521_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.00000000000000000000000000000000000000000004299 164.0
TLS2_k127_6707521_2 Rv0623-like transcription factor K19687 - - 0.00000000000000000002505 92.0
TLS2_k127_6707521_3 - - - - 0.0000000000000001196 81.0
TLS2_k127_6708042_0 efflux transmembrane transporter activity - - - 0.0 1043.0
TLS2_k127_6708042_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 342.0
TLS2_k127_6708042_2 Peptidase family M49 - - - 0.0000000000000000000000000000000000000000000000000001139 189.0
TLS2_k127_6708042_3 C-terminal region of aryl-sulfatase - - - 0.000000000000000000000000000000000000000000000003934 177.0
TLS2_k127_6708819_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1082.0
TLS2_k127_6708819_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000004885 85.0
TLS2_k127_6712862_0 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 604.0
TLS2_k127_6712862_1 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 464.0
TLS2_k127_6712862_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 358.0
TLS2_k127_6712862_3 CBD_II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 351.0
TLS2_k127_6712862_4 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005151 245.0
TLS2_k127_6712862_5 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000003555 213.0
TLS2_k127_6712862_6 Phage integrase family - - - 0.00000000000000000000000000000000000000000000001565 177.0
TLS2_k127_6712862_7 F-box LRR-repeat protein - - - 0.000000000000000000000000000000000000000000006017 186.0
TLS2_k127_6712862_8 f-box protein - - - 0.0001078 54.0
TLS2_k127_6713221_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 472.0
TLS2_k127_6713221_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 460.0
TLS2_k127_6713221_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 438.0
TLS2_k127_6713221_3 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 326.0
TLS2_k127_6713221_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000002372 144.0
TLS2_k127_6713221_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000003038 104.0
TLS2_k127_6713221_6 Domain of unknown function (DUF1844) - - - 0.0000000000000000004173 92.0
TLS2_k127_6726536_0 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 310.0
TLS2_k127_6726536_1 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000005835 244.0
TLS2_k127_6726536_2 -acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000009633 188.0
TLS2_k127_6726536_3 Protein conserved in bacteria - - - 0.0000000000000000001495 93.0
TLS2_k127_6727249_0 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000729 277.0
TLS2_k127_6727249_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000002018 235.0
TLS2_k127_6727249_2 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000006582 203.0
TLS2_k127_6727249_3 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000001088 166.0
TLS2_k127_6727249_4 Cupin domain - - - 0.000000000000000000000000000000001371 132.0
TLS2_k127_6727249_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000002668 93.0
TLS2_k127_6730382_0 Protein of unknown function (DUF1595) - - - 3.482e-313 977.0
TLS2_k127_6730382_1 Protein of unknown function (DUF1549) - - - 4.483e-260 841.0
TLS2_k127_6730382_10 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000009133 175.0
TLS2_k127_6730382_11 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC K09667 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.255 0.0000000002837 72.0
TLS2_k127_6730382_2 Cytochrome c - - - 2.305e-250 803.0
TLS2_k127_6730382_3 TonB-dependent receptor - - - 6.298e-226 739.0
TLS2_k127_6730382_4 Protein of unknown function (DUF1552) - - - 4.111e-221 692.0
TLS2_k127_6730382_5 ADP-ribosylglycohydrolase - - - 1.235e-202 653.0
TLS2_k127_6730382_6 Protein of unknown function (DUF1501) - - - 1.154e-196 623.0
TLS2_k127_6730382_7 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 613.0
TLS2_k127_6730382_8 ribosylpyrimidine nucleosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007644 282.0
TLS2_k127_6730382_9 GMC oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002003 277.0
TLS2_k127_6733102_0 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 485.0
TLS2_k127_6740348_0 Aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 329.0
TLS2_k127_6740348_1 BON domain - - - 0.0000000000000000001014 89.0
TLS2_k127_6741166_0 domain, Protein K12685,K16785,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 321.0
TLS2_k127_6741166_1 Sodium Bile acid symporter family K03453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 318.0
TLS2_k127_6741166_2 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 311.0
TLS2_k127_6741166_3 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001183 259.0
TLS2_k127_6741166_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000003423 198.0
TLS2_k127_6759398_0 Ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 587.0
TLS2_k127_6759398_1 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 311.0
TLS2_k127_6759398_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000001219 216.0
TLS2_k127_6759398_3 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000000000000003183 171.0
TLS2_k127_6759398_4 methyltransferase - - - 0.00000000000000000000000000000006924 133.0
TLS2_k127_6759398_5 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000002811 130.0
TLS2_k127_6759398_6 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000001018 112.0
TLS2_k127_6759398_7 PFAM PIN domain - - - 0.0000000000000000000001597 102.0
TLS2_k127_6759398_8 PFAM SpoVT AbrB - - - 0.00000000004396 68.0
TLS2_k127_6767544_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07640 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 339.0
TLS2_k127_6767544_1 PFAM response regulator receiver K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 317.0
TLS2_k127_6767544_2 ATP-independent chaperone mediated protein folding K06006 - - 0.00006764 51.0
TLS2_k127_6769717_0 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 505.0
TLS2_k127_6769717_1 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 399.0
TLS2_k127_6769717_2 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 302.0
TLS2_k127_6775238_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 320.0
TLS2_k127_6775238_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 289.0
TLS2_k127_6775238_2 zinc ion binding K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000003235 207.0
TLS2_k127_6775238_3 addiction module antidote protein HigA K21498 - - 0.000000000000000000000000000000388 125.0
TLS2_k127_6784534_0 - - - - 0.0000000000000000000000000000000000000741 147.0
TLS2_k127_6784534_2 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000008336 107.0
TLS2_k127_6784534_3 Protein of unknown function (DUF1587) - - - 0.000000000000000000001754 98.0
TLS2_k127_6792449_0 PQQ enzyme repeat K00117 - 1.1.5.2 4.007e-245 776.0
TLS2_k127_6792449_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 415.0
TLS2_k127_6792449_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000001772 68.0
TLS2_k127_6793140_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 404.0
TLS2_k127_6793140_1 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 379.0
TLS2_k127_6793140_2 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000003227 241.0
TLS2_k127_6802420_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1205.0
TLS2_k127_6802420_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.171e-236 734.0
TLS2_k127_6802420_10 Belongs to the MraZ family K03925 - - 0.0000000000000000000001067 103.0
TLS2_k127_6802420_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000002403 96.0
TLS2_k127_6802420_12 - K01822 - 5.3.3.1 0.000000000000000000006158 98.0
TLS2_k127_6802420_13 Peptidase, M16 K07263 - - 0.000376 50.0
TLS2_k127_6802420_14 VWA domain containing CoxE-like protein - - - 0.0004618 50.0
TLS2_k127_6802420_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 604.0
TLS2_k127_6802420_3 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 558.0
TLS2_k127_6802420_4 MgtE intracellular - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 426.0
TLS2_k127_6802420_5 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 411.0
TLS2_k127_6802420_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 343.0
TLS2_k127_6802420_7 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000005845 209.0
TLS2_k127_6802420_8 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000005196 182.0
TLS2_k127_6802420_9 - - - - 0.000000000000000000000000000000000000000000001563 171.0
TLS2_k127_68120_0 B12 binding domain - - - 3.992e-227 715.0
TLS2_k127_68120_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 569.0
TLS2_k127_6823241_0 PFAM von Willebrand factor type A K07114,K12511 - - 0.00000000000000000000000000000000000746 142.0
TLS2_k127_6823241_1 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000001227 139.0
TLS2_k127_6823241_2 Cytochrome c K00413 - - 0.0000000000144 67.0
TLS2_k127_6826559_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 472.0
TLS2_k127_6826559_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 410.0
TLS2_k127_6826559_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005845 256.0
TLS2_k127_6826559_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000005949 207.0
TLS2_k127_6833404_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 487.0
TLS2_k127_6833404_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001919 259.0
TLS2_k127_6833404_2 tRNA wobble adenosine to inosine editing - - - 0.000000000000000000000000000000000001053 147.0
TLS2_k127_6833404_3 Protein of unknown function (DUF433) - - - 0.00000000000000000000001217 103.0
TLS2_k127_6833404_4 - - - - 0.00000000000000000000001449 102.0
TLS2_k127_6833404_5 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000006946 84.0
TLS2_k127_6833404_6 - - - - 0.0000000002065 65.0
TLS2_k127_6839119_0 SMART ATPase, AAA type, core K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 298.0
TLS2_k127_6839119_1 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002638 259.0
TLS2_k127_6839119_2 PFAM Binding-protein-dependent transport system inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003149 249.0
TLS2_k127_6839119_3 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000001092 208.0
TLS2_k127_6839119_4 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000001643 72.0
TLS2_k127_6843717_0 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 487.0
TLS2_k127_6843717_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 308.0
TLS2_k127_6843717_2 DNA binding domain with preference for A/T rich regions K07491 - - 0.0000000000000000000000000000000000000000005261 168.0
TLS2_k127_6843717_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000001362 129.0
TLS2_k127_6857403_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 325.0
TLS2_k127_6857403_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 295.0
TLS2_k127_6857403_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000003227 187.0
TLS2_k127_6857403_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000001299 126.0
TLS2_k127_6857403_4 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0000000006732 61.0
TLS2_k127_6860451_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000953 275.0
TLS2_k127_6860451_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001424 272.0
TLS2_k127_6860451_2 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000002183 211.0
TLS2_k127_6860451_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000005541 151.0
TLS2_k127_6860451_4 Putative prokaryotic signal transducing protein - - - 0.00003648 51.0
TLS2_k127_6863940_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 471.0
TLS2_k127_6863940_1 PFAM Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 357.0
TLS2_k127_6863940_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000001839 202.0
TLS2_k127_6863940_3 found to be peripherally associated with the inner membrane in Escherichia coli K03499 - - 0.000000000004646 68.0
TLS2_k127_6863940_5 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.0000001998 55.0
TLS2_k127_6872045_0 Glycosyltransferase family 87 - - - 0.0000000000000000000000000000000000000000000000000000166 204.0
TLS2_k127_6872045_1 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000001499 87.0
TLS2_k127_6894980_0 MacB-like periplasmic core domain - - - 2.611e-305 960.0
TLS2_k127_6894980_1 Carboxypeptidase regulatory-like domain - - - 2.544e-221 714.0
TLS2_k127_6894980_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 600.0
TLS2_k127_6894980_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 366.0
TLS2_k127_6894980_4 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 358.0
TLS2_k127_6894980_5 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 322.0
TLS2_k127_6894980_6 amidohydrolase K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000001888 220.0
TLS2_k127_6894980_7 PQQ-like domain - - - 0.000000000000000000000000000000000000001438 153.0
TLS2_k127_6896317_0 MacB-like periplasmic core domain K02004 - - 1.622e-243 780.0
TLS2_k127_6896317_1 pfam abc K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 326.0
TLS2_k127_6896317_2 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000004194 215.0
TLS2_k127_6896317_3 PFAM ABC transporter related K01990,K19340 - - 0.000000000000000000000000000000000000000001293 166.0
TLS2_k127_6905609_0 Surface antigen variable number K07277 - - 0.0 1024.0
TLS2_k127_6905609_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 429.0
TLS2_k127_6905609_10 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.000008153 59.0
TLS2_k127_6905609_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 376.0
TLS2_k127_6905609_3 aldo keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 372.0
TLS2_k127_6905609_4 STAS domain K04749 - - 0.000000000000000000000000000000000000000000000000145 186.0
TLS2_k127_6905609_5 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000000000000008314 129.0
TLS2_k127_6905609_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000005433 117.0
TLS2_k127_6905609_7 - - - - 0.0000000000000151 82.0
TLS2_k127_6905609_8 Transcriptional regulator K07734 - - 0.00000000000001531 74.0
TLS2_k127_6905609_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000006648 65.0
TLS2_k127_6905766_0 Y_Y_Y domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 574.0
TLS2_k127_6905766_1 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 374.0
TLS2_k127_6905766_2 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 289.0
TLS2_k127_6905766_4 - - - - 0.0000000000000002072 83.0
TLS2_k127_6913673_0 glycolate transport K14393 - - 4.404e-227 715.0
TLS2_k127_6913673_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 4.185e-210 672.0
TLS2_k127_6913673_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 7.537e-196 619.0
TLS2_k127_6913673_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 530.0
TLS2_k127_6913673_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 297.0
TLS2_k127_6913673_5 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000001343 227.0
TLS2_k127_6913673_6 - - - - 0.0000000000000000000000000000000000000000002113 165.0
TLS2_k127_6913673_7 Protein of unknown function, DUF485 - - - 0.000000000000000000000002956 106.0
TLS2_k127_6913673_8 response regulator, receiver - - - 0.000000002466 61.0
TLS2_k127_6929467_0 competence protein COMEC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 490.0
TLS2_k127_6929467_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 454.0
TLS2_k127_6929467_2 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 305.0
TLS2_k127_6929467_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000005648 102.0
TLS2_k127_6938265_0 PFAM Sulfatase K01130 - 3.1.6.1 2.529e-194 621.0
TLS2_k127_6938265_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001031 257.0
TLS2_k127_6938265_2 Dehydrogenase K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000002136 247.0
TLS2_k127_6938265_3 Integrase core domain - - - 0.0000006516 51.0
TLS2_k127_69553_0 Phosphomethylpyrimidine kinase K00882 - 2.7.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004781 282.0
TLS2_k127_69553_1 teichoic acid transport K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000009195 239.0
TLS2_k127_69553_2 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000009255 122.0
TLS2_k127_69553_3 - - - - 0.0000000000000000001846 91.0
TLS2_k127_69553_4 Tetratricopeptide repeat - - - 0.0009594 44.0
TLS2_k127_695599_0 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 387.0
TLS2_k127_695599_1 Zinc-binding dehydrogenase K00001,K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 308.0
TLS2_k127_695599_2 cyclopropane-fatty-acyl-phospholipid synthase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000126 179.0
TLS2_k127_6967275_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 405.0
TLS2_k127_6967275_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 335.0
TLS2_k127_6967275_2 PRC-barrel domain - - - 0.000000000000000000000000000000000000000000002613 168.0
TLS2_k127_6967275_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000003895 141.0
TLS2_k127_6967275_4 phosphorelay signal transduction system - - - 0.000000001683 65.0
TLS2_k127_6981340_0 Carboxypeptidase regulatory-like domain - - - 0.0 1230.0
TLS2_k127_6981340_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 421.0
TLS2_k127_6981340_10 Belongs to the peptidase S26 family - - - 0.00000000000000000000000000000000000001741 149.0
TLS2_k127_6981340_11 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000001684 146.0
TLS2_k127_6981340_12 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000001031 129.0
TLS2_k127_6981340_2 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 286.0
TLS2_k127_6981340_3 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008586 287.0
TLS2_k127_6981340_4 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003333 269.0
TLS2_k127_6981340_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001088 241.0
TLS2_k127_6981340_6 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000002178 187.0
TLS2_k127_6981340_7 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000637 173.0
TLS2_k127_6981340_8 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000004854 157.0
TLS2_k127_6981340_9 PFAM Redoxin - - - 0.000000000000000000000000000000000000008664 151.0
TLS2_k127_6992051_0 TIGRFAM ATPase, FliI YscN family K02412 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 579.0
TLS2_k127_6992051_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 484.0
TLS2_k127_6992051_10 Flagellar assembly protein FliH K02411 - - 0.000000004182 65.0
TLS2_k127_6992051_2 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 401.0
TLS2_k127_6992051_3 flagellar motor switch protein FliG K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002578 270.0
TLS2_k127_6992051_4 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000002491 248.0
TLS2_k127_6992051_5 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.000000000000000000000000000000000000000000000000001086 184.0
TLS2_k127_6992051_6 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000003083 186.0
TLS2_k127_6992051_7 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000000007221 159.0
TLS2_k127_6992051_8 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000138 153.0
TLS2_k127_6992051_9 DnaJ molecular chaperone homology domain - - - 0.00000000000000000001262 106.0
TLS2_k127_69923_0 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008507 266.0
TLS2_k127_69923_1 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001938 234.0
TLS2_k127_7013813_0 Cytochrome c, class I - - - 7.51e-224 709.0
TLS2_k127_7013813_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000004218 225.0
TLS2_k127_7020327_0 esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 398.0
TLS2_k127_7020327_1 bacterial OsmY and nodulation domain K04065 - - 0.00000002141 57.0
TLS2_k127_7024421_0 cellulose binding - - - 0.0000000000000000000000000000000000000002181 173.0
TLS2_k127_7024421_1 Sulfatase - - - 0.000000005491 63.0
TLS2_k127_7024421_2 Beta-propeller repeat - - - 0.0003709 54.0
TLS2_k127_7024629_0 protocatechuate 3,4-dioxygenase activity - - - 1.83e-199 664.0
TLS2_k127_7024629_1 NhaP-type Na H and K H - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 530.0
TLS2_k127_7024629_10 - - - - 0.0000000000000000000000000002157 122.0
TLS2_k127_7024629_11 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures - - - 0.00000000000000000000004291 111.0
TLS2_k127_7024629_12 - - - - 0.000004929 52.0
TLS2_k127_7024629_2 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 494.0
TLS2_k127_7024629_3 Putative serine dehydratase domain K01753 - 4.3.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 363.0
TLS2_k127_7024629_4 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 295.0
TLS2_k127_7024629_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000003686 205.0
TLS2_k127_7024629_6 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000002004 182.0
TLS2_k127_7024629_7 PFAM Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000007011 151.0
TLS2_k127_7024629_8 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000007918 145.0
TLS2_k127_7024629_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000001366 129.0
TLS2_k127_7032686_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 328.0
TLS2_k127_7032686_1 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001052 233.0
TLS2_k127_7043086_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.953e-287 893.0
TLS2_k127_7043086_1 AMP-binding enzyme C-terminal domain - - - 1.333e-213 675.0
TLS2_k127_7043086_2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 496.0
TLS2_k127_7043086_3 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000003851 217.0
TLS2_k127_7043086_4 KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000005923 188.0
TLS2_k127_7043086_5 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000008182 120.0
TLS2_k127_7043086_6 - - - - 0.00000000000000000008501 94.0
TLS2_k127_7046716_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008957 259.0
TLS2_k127_7046716_1 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000000000001754 213.0
TLS2_k127_7046716_2 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000007097 199.0
TLS2_k127_7046716_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000001102 169.0
TLS2_k127_7046716_4 TIGRFAM RHS repeat-associated core domain - - - 0.000000000000000003401 98.0
TLS2_k127_7046716_5 nuclease - - - 0.00000005911 65.0
TLS2_k127_7046716_6 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00002314 47.0
TLS2_k127_7081995_0 Protein of unknown function (DUF4256) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 329.0
TLS2_k127_7081995_2 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000008223 168.0
TLS2_k127_7081995_3 membrane - - - 0.0000000000000000000000000000000002087 142.0
TLS2_k127_7081995_4 Cro/C1-type HTH DNA-binding domain K07727 - - 0.000000000000000000000000009132 117.0
TLS2_k127_7081995_5 Alpha/beta hydrolase family - - - 0.0000004792 57.0
TLS2_k127_7085192_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 433.0
TLS2_k127_7085192_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000001123 220.0
TLS2_k127_7085192_2 cellulose binding - - - 0.0000000000000000000000000000000000000000007098 169.0
TLS2_k127_7085192_3 YbbR-like protein - - - 0.000000000000000000000000000000004944 136.0
TLS2_k127_7101656_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.996e-321 1002.0
TLS2_k127_7101656_1 Sodium:sulfate symporter transmembrane region K03319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 542.0
TLS2_k127_7101656_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 327.0
TLS2_k127_7101656_3 amino acid - - - 0.0000000000000000000000003544 106.0
TLS2_k127_7101656_4 Protein of unknown function (DUF3311) - - - 0.000000001622 61.0
TLS2_k127_7113371_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 479.0
TLS2_k127_7113371_1 PFAM type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 478.0
TLS2_k127_7113371_2 RNA binding K06959 - - 0.00000000000000000000000000000000000000000000000000000005114 210.0
TLS2_k127_7113371_3 - - - - 0.0000000000000000000000000000000000000000000000002053 184.0
TLS2_k127_7113371_4 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000006095 120.0
TLS2_k127_7113371_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000000000000008976 90.0
TLS2_k127_7113711_0 DNA topological change K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 586.0
TLS2_k127_7113711_1 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 345.0
TLS2_k127_7137411_0 histone H2A K63-linked ubiquitination K00925,K08884,K11894 - 2.7.11.1,2.7.2.1 9.093e-265 836.0
TLS2_k127_7137411_1 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 498.0
TLS2_k127_7137411_10 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000002113 98.0
TLS2_k127_7137411_11 - - - - 0.00000000000000612 87.0
TLS2_k127_7137411_13 Putative zinc-finger - - - 0.00003892 55.0
TLS2_k127_7137411_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 473.0
TLS2_k127_7137411_3 histone H2A K63-linked ubiquitination K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 434.0
TLS2_k127_7137411_4 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 424.0
TLS2_k127_7137411_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 340.0
TLS2_k127_7137411_6 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000004341 162.0
TLS2_k127_7137411_7 Glycine oxidase K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 0.000000000000000000000000000000000000000007544 169.0
TLS2_k127_7137411_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000006523 160.0
TLS2_k127_7137411_9 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000004856 130.0
TLS2_k127_7148167_0 HELICc2 K03722 - 3.6.4.12 2.448e-273 854.0
TLS2_k127_7148167_1 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 1.634e-201 643.0
TLS2_k127_7148167_2 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003935 265.0
TLS2_k127_7148167_3 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004475 266.0
TLS2_k127_7148167_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000243 188.0
TLS2_k127_7148167_5 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000002616 149.0
TLS2_k127_7150730_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 537.0
TLS2_k127_7150730_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000007899 157.0
TLS2_k127_7150730_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000003465 127.0
TLS2_k127_7150730_3 Ribosomal RNA adenine dimethylase - - - 0.000000000000000000000000084 114.0
TLS2_k127_7150730_4 PFAM Rv0623 family protein transcription factor K19687 - - 0.0000000000000000000000002278 108.0
TLS2_k127_7150730_5 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000004241 69.0
TLS2_k127_7150730_6 Plasmid stabilization system - - - 0.0000000000041 70.0
TLS2_k127_7150730_7 Putative addiction module component - - - 0.00000000005894 65.0
TLS2_k127_7150730_8 - - - - 0.000002813 54.0
TLS2_k127_7155179_0 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 372.0
TLS2_k127_7155179_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 359.0
TLS2_k127_7155179_2 COG0454 Histone acetyltransferase HPA2 and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 355.0
TLS2_k127_7155179_3 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 289.0
TLS2_k127_7155179_4 COG0454 Histone acetyltransferase HPA2 and related - - - 0.0000000000000000000000000000000000000000000000000000001918 202.0
TLS2_k127_7155179_5 Glycosyl hydrolase family 57 K22278 - 3.5.1.104 0.0000000000000000000000000000000000003019 149.0
TLS2_k127_7155179_6 L-seryl-tRNASec selenium transferase activity - - - 0.00008874 46.0
TLS2_k127_7167797_0 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000000000000000000001594 116.0
TLS2_k127_7167797_1 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000000003934 100.0
TLS2_k127_7167797_2 membrane K00860,K00956 - 2.7.1.25,2.7.7.4 0.00000000000000237 78.0
TLS2_k127_7167797_3 PFAM Na Pi-cotransporter K03324 - - 0.00000000005553 64.0
TLS2_k127_7183235_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 524.0
TLS2_k127_7183235_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002132 265.0
TLS2_k127_7183235_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000001487 191.0
TLS2_k127_7183235_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000001464 162.0
TLS2_k127_7183235_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000001504 135.0
TLS2_k127_7183235_6 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000002247 91.0
TLS2_k127_7183235_7 lipoprotein localization to outer membrane K02004 - - 0.00000000000003303 75.0
TLS2_k127_7189591_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000005629 252.0
TLS2_k127_7189591_1 Trypsin K04771 - 3.4.21.107 0.0000000000000000000001419 102.0
TLS2_k127_7189591_2 - - - - 0.00000000000000003095 84.0
TLS2_k127_7189591_3 large ribosomal subunit rRNA binding K02884 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000002364 70.0
TLS2_k127_7280706_0 Domain of unknown function (DUF5060) - - - 8.327e-199 638.0
TLS2_k127_7280706_1 Type III effector Hrp-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 464.0
TLS2_k127_7280706_2 Phosphogluconate dehydrogenase (decarboxylating) C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 351.0
TLS2_k127_7280706_3 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 338.0
TLS2_k127_7280706_4 FCD K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000002205 243.0
TLS2_k127_7280706_5 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000007236 227.0
TLS2_k127_7307515_0 Glucose / Sorbosone dehydrogenase - - - 6.192e-226 706.0
TLS2_k127_7307515_1 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000002587 273.0
TLS2_k127_7307515_2 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.000000000000000002295 96.0
TLS2_k127_73747_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 330.0
TLS2_k127_7434853_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 506.0
TLS2_k127_7434853_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 291.0
TLS2_k127_7434853_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000009423 261.0
TLS2_k127_7434853_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004664 253.0
TLS2_k127_7434853_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000001924 170.0
TLS2_k127_7434853_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000001994 160.0
TLS2_k127_745182_0 MFP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 409.0
TLS2_k127_745182_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 364.0
TLS2_k127_745182_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 334.0
TLS2_k127_756310_0 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds K01666 - 4.1.3.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 519.0
TLS2_k127_756310_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 456.0
TLS2_k127_756310_2 Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds K04073 - 1.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 432.0
TLS2_k127_756310_3 Malate/L-lactate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 313.0
TLS2_k127_756310_4 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 311.0
TLS2_k127_756310_5 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 289.0
TLS2_k127_756310_6 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000005165 222.0
TLS2_k127_756310_7 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000001988 221.0
TLS2_k127_756310_8 KR domain K00059 - 1.1.1.100 0.000000291 52.0
TLS2_k127_757427_0 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000002238 183.0
TLS2_k127_757427_3 TadE-like protein - - - 0.0001823 50.0
TLS2_k127_80525_0 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 417.0
TLS2_k127_80525_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 389.0
TLS2_k127_80525_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 362.0
TLS2_k127_80525_3 Phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 353.0
TLS2_k127_80525_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000006843 190.0
TLS2_k127_80525_5 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000001718 147.0
TLS2_k127_808059_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 3.327e-304 943.0
TLS2_k127_808059_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008386 282.0
TLS2_k127_831524_0 cytochrome C peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001005 276.0
TLS2_k127_831524_1 transport system, permease component K01992 - - 0.0000000001393 64.0
TLS2_k127_831524_2 Lipid A 3-O-deacylase (PagL) - - - 0.0000000001415 69.0
TLS2_k127_83412_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 426.0
TLS2_k127_83412_1 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 260.0
TLS2_k127_83412_2 protein domain associated with - - - 0.000000000000000000000000000000000000000000000000000000000000000002331 235.0
TLS2_k127_83412_3 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000005285 149.0
TLS2_k127_83412_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000002596 105.0
TLS2_k127_862015_0 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 379.0
TLS2_k127_87487_1 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.00001898 57.0
TLS2_k127_87487_2 photosynthesis - - - 0.00004403 55.0
TLS2_k127_903431_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1244.0
TLS2_k127_903431_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 411.0
TLS2_k127_903431_2 sulfate ABC transporter K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000001842 231.0
TLS2_k127_93222_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 2.864e-295 942.0
TLS2_k127_93222_1 - - - - 6.766e-195 616.0
TLS2_k127_93222_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 597.0
TLS2_k127_93222_3 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 610.0
TLS2_k127_93222_4 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 389.0
TLS2_k127_93222_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000001612 138.0
TLS2_k127_93222_6 Stage II sporulation protein E (SpoIIE) - - - 0.00000000000000000008035 102.0
TLS2_k127_946634_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 462.0
TLS2_k127_946634_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000001082 186.0
TLS2_k127_946634_2 YtxH-like protein - - - 0.00007549 48.0
TLS2_k127_948516_0 Transposase (IS116 IS110 IS902 family) K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 383.0
TLS2_k127_948516_1 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000911 277.0
TLS2_k127_948516_2 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000003167 201.0
TLS2_k127_948876_0 TonB-dependent receptor - - - 2.52e-249 802.0
TLS2_k127_948876_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.438e-198 637.0
TLS2_k127_955565_0 ANTAR K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 311.0
TLS2_k127_955565_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000001324 161.0
TLS2_k127_955565_2 PFAM Archaeal ATPase - - - 0.000000000000000000000000000000002816 150.0
TLS2_k127_955565_3 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000007799 96.0
TLS2_k127_957455_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.0 1199.0
TLS2_k127_957455_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.52e-244 764.0
TLS2_k127_957455_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000001245 199.0
TLS2_k127_960037_0 Tetratricopeptide repeat - - - 6.234e-258 805.0
TLS2_k127_960037_1 Protein of unknown function (DUF1501) - - - 1.372e-230 722.0
TLS2_k127_960037_2 Protein of unknown function (DUF1549) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 501.0
TLS2_k127_960037_3 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000000000000000000000000000000000000002995 213.0
TLS2_k127_960924_0 Peptidase M16 - - - 0.0 1102.0
TLS2_k127_960924_1 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 329.0
TLS2_k127_960924_2 PFAM Alpha beta hydrolase K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 296.0
TLS2_k127_960924_3 PFAM Surface antigen variable number K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001757 262.0
TLS2_k127_960924_4 AhpC TSA family - - - 0.00000000001157 72.0
TLS2_k127_972016_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 415.0
TLS2_k127_972016_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000158 228.0
TLS2_k127_972016_2 PFAM Rhodanese domain protein - - - 0.0000000000000000009377 93.0
TLS2_k127_974382_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 9.867e-257 799.0
TLS2_k127_974382_1 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 501.0
TLS2_k127_974382_2 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 440.0
TLS2_k127_974382_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 399.0
TLS2_k127_974382_4 amine dehydrogenase activity K12287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 318.0
TLS2_k127_974382_5 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000615 249.0
TLS2_k127_979130_0 acetylesterase activity K01181 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001018 286.0
TLS2_k127_979130_1 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000001812 146.0
TLS2_k127_979130_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000007368 92.0
TLS2_k127_979130_3 pfam rdd - - - 0.00000000000004689 84.0
TLS2_k127_979274_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1210.0
TLS2_k127_979274_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 8.797e-211 659.0
TLS2_k127_979274_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 601.0
TLS2_k127_979274_3 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000001053 177.0
TLS2_k127_979274_4 Peptidase, M16 K07263 - - 0.000000001085 68.0
TLS2_k127_979796_0 Glycosyl transferase, family 2 K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 428.0
TLS2_k127_979796_1 Response regulator, receiver - - - 0.000002444 59.0
TLS2_k127_981789_0 Dehydrogenase E1 component K11381 - 1.2.4.4 2.42e-303 944.0
TLS2_k127_981789_1 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 314.0
TLS2_k127_981789_2 unfolded protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009485 253.0
TLS2_k127_981789_3 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000007092 71.0
TLS2_k127_982706_0 kinase activity K21948 - 2.7.1.217 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 494.0
TLS2_k127_982706_1 Class ii aldolase K01628,K22130 - 4.1.1.104,4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 314.0
TLS2_k127_985078_0 TonB-dependent Receptor Plug K16090 - - 4.093e-266 846.0
TLS2_k127_985078_1 2OG-Fe(II) oxygenase K07336 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 372.0
TLS2_k127_985078_2 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 310.0
TLS2_k127_985078_3 - - - - 0.00000000000000000000000000000000254 140.0
TLS2_k127_985078_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000005642 75.0
TLS2_k127_985078_5 PepSY-associated TM region - - - 0.000000000003484 67.0
TLS2_k127_986670_0 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000017 81.0
TLS2_k127_986670_2 - - - - 0.000005682 48.0
TLS2_k127_987157_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 503.0
TLS2_k127_987157_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 433.0
TLS2_k127_987157_10 Cytochrome c - - - 0.0000002848 56.0
TLS2_k127_987157_2 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 418.0
TLS2_k127_987157_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 382.0
TLS2_k127_987157_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 315.0
TLS2_k127_987157_6 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001778 246.0
TLS2_k127_987157_7 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000000003242 192.0
TLS2_k127_987157_8 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000000000000001334 100.0
TLS2_k127_987157_9 BON domain - - - 0.000000000000000008728 91.0
TLS2_k127_989399_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 559.0
TLS2_k127_989399_1 Dienelactone hydrolase family - - - 0.00000000000000000234 87.0
TLS2_k127_99897_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 368.0