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Overview

ID MAG04002
Name TLS2_bin.38
Sample SMP0104
Taxonomy
Kingdom Bacteria
Phylum Verrucomicrobiota
Class Verrucomicrobiia
Order Limisphaerales
Family JAHDYP01
Genus JAHDYP01
Species
Assembly information
Completeness (%) 83.99
Contamination (%) 4.71
GC content (%) 60.0
N50 (bp) 10,592
Genome size (bp) 4,960,809

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4001

Gene name Description KEGG GOs EC E-value Score Sequence
TLS2_k127_1009416_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001719 277.0
TLS2_k127_1024543_0 amidohydrolase - - - 3.933e-283 883.0
TLS2_k127_1024543_1 Transmembrane secretion effector K08225 - - 7.641e-219 691.0
TLS2_k127_1024543_2 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 414.0
TLS2_k127_1024543_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 359.0
TLS2_k127_1024543_4 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 337.0
TLS2_k127_1024543_5 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 317.0
TLS2_k127_1024543_6 - - - - 0.00000000000000001672 83.0
TLS2_k127_1024543_7 - - - - 0.000000000001575 76.0
TLS2_k127_1024543_8 Belongs to the pirin family K06911 - - 0.000000000006335 66.0
TLS2_k127_1029401_0 PAS sensor protein K13243 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008081,GO:0008144,GO:0008150,GO:0009628,GO:0016787,GO:0016788,GO:0019825,GO:0019826,GO:0020037,GO:0036094,GO:0042578,GO:0043167,GO:0043169,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0070482,GO:0071111,GO:0097159,GO:1901363 3.1.4.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 336.0
TLS2_k127_1029401_1 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002958 244.0
TLS2_k127_1029401_2 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000003118 211.0
TLS2_k127_1029401_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000003134 135.0
TLS2_k127_1031612_0 pathogenesis K18286,K20276 - 3.5.4.40 0.0 1562.0
TLS2_k127_1031612_1 cellulose binding - - - 0.000000000000000000000000002422 132.0
TLS2_k127_1031612_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000401 68.0
TLS2_k127_1046365_0 SMART PAS domain containing protein - - - 2.087e-240 786.0
TLS2_k127_1046365_1 pentaerythritol trinitrate reductase activity - - - 1.148e-215 679.0
TLS2_k127_1046365_10 GGDEF domain - - - 0.00000000000000000000000000000000000000002851 167.0
TLS2_k127_1046365_11 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000003293 157.0
TLS2_k127_1046365_12 PFAM Smr protein MutS2 - - - 0.000000000000000000000000000002769 124.0
TLS2_k127_1046365_13 PFAM response regulator receiver K03413 - - 0.0000000000000003084 91.0
TLS2_k127_1046365_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.00000000000001264 80.0
TLS2_k127_1046365_15 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division K08304 GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016787,GO:0016798,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000004119 58.0
TLS2_k127_1046365_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 627.0
TLS2_k127_1046365_3 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 550.0
TLS2_k127_1046365_4 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 496.0
TLS2_k127_1046365_5 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 479.0
TLS2_k127_1046365_6 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 429.0
TLS2_k127_1046365_7 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 384.0
TLS2_k127_1046365_8 SCO1/SenC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002248 286.0
TLS2_k127_1046365_9 Hit family K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000009507 173.0
TLS2_k127_1047067_0 High confidence in function and specificity - - - 4.911e-194 633.0
TLS2_k127_1047067_1 Transposase, IS605 OrfB family - - - 0.0002103 45.0
TLS2_k127_1051717_0 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 350.0
TLS2_k127_1051717_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 329.0
TLS2_k127_1051717_2 Bacterial PH domain - - - 0.0000000000000000000000000000009768 128.0
TLS2_k127_1051717_3 - - - - 0.000000000002248 69.0
TLS2_k127_1064052_0 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000007163 163.0
TLS2_k127_1064052_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000006937 140.0
TLS2_k127_1064052_2 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000007297 144.0
TLS2_k127_1064630_0 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 414.0
TLS2_k127_1064630_1 AIPR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000206 293.0
TLS2_k127_1089927_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 6.163e-319 985.0
TLS2_k127_1089927_1 alginic acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 648.0
TLS2_k127_1089927_2 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 580.0
TLS2_k127_1089927_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 427.0
TLS2_k127_1089927_4 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 373.0
TLS2_k127_1089927_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001877 250.0
TLS2_k127_1089927_6 - K00241 - - 0.000000000000000000000000000000000000000000000000000000002293 208.0
TLS2_k127_1089927_7 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000006782 134.0
TLS2_k127_1089927_8 displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity K05516 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000000000000000003394 107.0
TLS2_k127_1090698_0 ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 387.0
TLS2_k127_1090698_1 mannitol 2-dehydrogenase activity K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 369.0
TLS2_k127_1090698_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 328.0
TLS2_k127_1090698_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 325.0
TLS2_k127_1090698_4 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001057 282.0
TLS2_k127_1090698_5 cheY-homologous receiver domain K02485 - - 0.00000000000000000000000000000000000009497 147.0
TLS2_k127_1090698_6 PFAM response regulator receiveR - - - 0.0000000000000000000000000000001549 127.0
TLS2_k127_1090698_7 - - - - 0.000000000005462 75.0
TLS2_k127_1091185_0 TrkA-C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 502.0
TLS2_k127_1091185_1 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 483.0
TLS2_k127_1091185_10 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001777 273.0
TLS2_k127_1091185_11 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000009029 271.0
TLS2_k127_1091185_12 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001406 265.0
TLS2_k127_1091185_13 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001558 258.0
TLS2_k127_1091185_14 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000004201 190.0
TLS2_k127_1091185_15 - - - - 0.000000000000000000000000000000000000000000000002126 183.0
TLS2_k127_1091185_16 Prokaryotic N-terminal methylation motif - - - 0.0000000000003696 81.0
TLS2_k127_1091185_17 cell redox homeostasis - - - 0.0000000000009435 78.0
TLS2_k127_1091185_18 - - - - 0.00000000004076 68.0
TLS2_k127_1091185_19 - - - - 0.00000001169 62.0
TLS2_k127_1091185_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 470.0
TLS2_k127_1091185_20 thiamine biosynthesis protein ThiS K03154 - - 0.0000002405 54.0
TLS2_k127_1091185_21 - - - - 0.00000065 51.0
TLS2_k127_1091185_3 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 465.0
TLS2_k127_1091185_4 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 436.0
TLS2_k127_1091185_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 423.0
TLS2_k127_1091185_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 389.0
TLS2_k127_1091185_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 340.0
TLS2_k127_1091185_8 COG1914 Mn2 and Fe2 transporters of the NRAMP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 303.0
TLS2_k127_1091185_9 PFAM glutamine amidotransferase class-I K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 285.0
TLS2_k127_10982_0 Belongs to the glycosyl hydrolase 2 family - - - 1.598e-270 848.0
TLS2_k127_10982_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 466.0
TLS2_k127_1130695_0 Pirin C-terminal cupin domain K06911 - - 8.511e-195 608.0
TLS2_k127_1130695_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 512.0
TLS2_k127_1130695_2 GCN5-related N-acetyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001262 262.0
TLS2_k127_1130695_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000003072 242.0
TLS2_k127_1131793_0 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 384.0
TLS2_k127_1131793_1 Male sterility protein K00091,K19997 - 1.1.1.219,5.1.3.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 338.0
TLS2_k127_1131793_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 324.0
TLS2_k127_1131793_3 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 323.0
TLS2_k127_1131793_4 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000001301 256.0
TLS2_k127_1131793_5 - - - - 0.0000000000000000000000000004386 128.0
TLS2_k127_1131793_6 aminopeptidase activity - - - 0.0000000000000000000000000005937 114.0
TLS2_k127_1131793_7 Pfam:HipA_N K07154 - 2.7.11.1 0.0000007985 54.0
TLS2_k127_1132070_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 256.0
TLS2_k127_1132070_1 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000001776 72.0
TLS2_k127_1136958_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 8.148e-303 942.0
TLS2_k127_1136958_1 Glycogen debranching enzyme N terminal - - - 3.652e-272 854.0
TLS2_k127_1136958_10 ribosylpyrimidine nucleosidase activity K01250 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 383.0
TLS2_k127_1136958_11 Domain of unknown function (DUF5060) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 360.0
TLS2_k127_1136958_12 Fungal family of unknown function (DUF1776) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 327.0
TLS2_k127_1136958_13 sigma-54 factor interaction domain-containing protein K11384 - - 0.00000000000000000000000000000000000000000000000000000000002012 209.0
TLS2_k127_1136958_14 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000000000000000000000000000000000000000006272 199.0
TLS2_k127_1136958_15 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000003594 181.0
TLS2_k127_1136958_16 Ferredoxin - - - 0.0000000000000000000000000000000000000000001241 161.0
TLS2_k127_1136958_17 Domain of unknown function (DUF892) - - - 0.0000000000000000000000000000000000000001321 157.0
TLS2_k127_1136958_18 Predicted membrane protein (DUF2243) - - - 0.000000000000000000000000000000000000001382 153.0
TLS2_k127_1136958_19 LysR substrate binding domain - - - 0.0000000000000000000000000000000000002951 143.0
TLS2_k127_1136958_2 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.384e-258 814.0
TLS2_k127_1136958_20 Protein of unknown function (DUF1360) - - - 0.0000000000000000000000000000000002154 142.0
TLS2_k127_1136958_21 CsbD-like - - - 0.000000000000000000000003131 105.0
TLS2_k127_1136958_22 Protein of unknown function (DUF3309) - - - 0.00000000000000004671 82.0
TLS2_k127_1136958_23 Protein of unknwon function (DUF3008) - - - 0.000000000009871 72.0
TLS2_k127_1136958_25 ribosome binding - - - 0.00000004992 58.0
TLS2_k127_1136958_3 Thi4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 598.0
TLS2_k127_1136958_4 Rhodanese domain protein K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 554.0
TLS2_k127_1136958_5 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 493.0
TLS2_k127_1136958_6 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 479.0
TLS2_k127_1136958_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 449.0
TLS2_k127_1136958_8 Glycosyl hydrolases family 2 K01190 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 481.0
TLS2_k127_1136958_9 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 430.0
TLS2_k127_1142468_0 pyrroloquinoline quinone binding - - - 7.584e-255 821.0
TLS2_k127_1142468_1 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 549.0
TLS2_k127_1142468_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000136 168.0
TLS2_k127_1142468_11 Protein of unknown function (DUF1573) - - - 0.00000000000007857 83.0
TLS2_k127_1142468_12 Rhodanese Homology Domain - - - 0.0000002529 61.0
TLS2_k127_1142468_13 by modhmm - - - 0.0000003272 64.0
TLS2_k127_1142468_14 Methylamine utilisation protein MauE - - - 0.0001542 50.0
TLS2_k127_1142468_2 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 508.0
TLS2_k127_1142468_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 498.0
TLS2_k127_1142468_4 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 389.0
TLS2_k127_1142468_5 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 376.0
TLS2_k127_1142468_6 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 374.0
TLS2_k127_1142468_7 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 347.0
TLS2_k127_1142468_8 Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 332.0
TLS2_k127_1142468_9 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 319.0
TLS2_k127_1146397_0 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000002224 166.0
TLS2_k127_1146397_1 - - - - 0.000000000000000000000000000000000006638 140.0
TLS2_k127_1146397_2 DNA integration K07497 - - 0.00000000000001832 76.0
TLS2_k127_1146397_3 DNA integration K07497 - - 0.00000000000004923 83.0
TLS2_k127_1146397_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000001378 73.0
TLS2_k127_1146397_5 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.00005667 50.0
TLS2_k127_1162578_0 beta-N-acetylglucosaminidase - GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 345.0
TLS2_k127_1162578_1 Binding-protein-dependent transport systems inner membrane component K02026,K10202 - - 0.000000000000000000000000000000000000000000000000000000000000003298 231.0
TLS2_k127_1162578_2 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000001471 215.0
TLS2_k127_1162578_3 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000003893 223.0
TLS2_k127_1162578_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000007444 182.0
TLS2_k127_1162578_5 Binding-protein-dependent transport system inner membrane component K10118 - - 0.0001514 48.0
TLS2_k127_1177058_0 PFAM glycosyl transferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 2.787e-260 822.0
TLS2_k127_1177058_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 508.0
TLS2_k127_1177058_2 L-fucose isomerase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 388.0
TLS2_k127_1177058_3 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 330.0
TLS2_k127_1177058_4 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000001084 198.0
TLS2_k127_1177058_5 heme-binding domain, Pirellula Verrucomicrobium type - - - 0.000000000000000000000000000000000000000000000000000007645 207.0
TLS2_k127_1177641_0 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 365.0
TLS2_k127_1177641_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 314.0
TLS2_k127_1177641_2 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000008012 189.0
TLS2_k127_1177641_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000005088 184.0
TLS2_k127_1177641_4 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.00000000000000000000005777 108.0
TLS2_k127_1177641_5 regulator - - - 0.000000000000000006385 90.0
TLS2_k127_1191740_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 531.0
TLS2_k127_1191740_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 511.0
TLS2_k127_1191740_2 COG0604 NADPH quinone reductase and related Zn-dependent K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 434.0
TLS2_k127_1191740_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 303.0
TLS2_k127_1191740_4 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 293.0
TLS2_k127_1191740_5 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004668 260.0
TLS2_k127_1191740_6 PFAM Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000002307 201.0
TLS2_k127_1191740_7 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000001252 136.0
TLS2_k127_1194711_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 434.0
TLS2_k127_1194711_1 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 291.0
TLS2_k127_1194711_2 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.0000000000000000000000001906 110.0
TLS2_k127_1194711_3 Esterase-like activity of phytase - - - 0.0000000548 64.0
TLS2_k127_1195990_0 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 309.0
TLS2_k127_1195990_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000005128 153.0
TLS2_k127_1195990_3 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000002084 93.0
TLS2_k127_1223296_0 ABC transporter C-terminal domain - - - 1.727e-275 861.0
TLS2_k127_1223296_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 379.0
TLS2_k127_1223296_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 318.0
TLS2_k127_1223296_3 PFAM glycosyl transferase, family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000009187 222.0
TLS2_k127_1223296_4 metallopeptidase activity - - - 0.00000000000000000000000000000001242 142.0
TLS2_k127_1223296_5 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000007631 80.0
TLS2_k127_1223296_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000008717 80.0
TLS2_k127_1223296_7 SMART Transport-associated and nodulation region K04065 - - 0.0000000007375 66.0
TLS2_k127_1226302_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1208.0
TLS2_k127_1226302_1 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 535.0
TLS2_k127_1226302_10 Purple acid Phosphatase, N-terminal domain - - - 0.00000001569 70.0
TLS2_k127_1226302_11 COG0530 Ca2 Na antiporter K07301 - - 0.00008558 47.0
TLS2_k127_1226302_2 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 424.0
TLS2_k127_1226302_3 GTP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 432.0
TLS2_k127_1226302_4 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 321.0
TLS2_k127_1226302_5 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 315.0
TLS2_k127_1226302_6 nitrite transporter K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 312.0
TLS2_k127_1226302_7 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000106 273.0
TLS2_k127_1226302_8 Rieske 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000000000000000001666 218.0
TLS2_k127_1226302_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000002473 115.0
TLS2_k127_12518_0 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 591.0
TLS2_k127_12518_1 Glycosyl-hydrolase 97 N-terminal K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 399.0
TLS2_k127_12518_2 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 382.0
TLS2_k127_12518_3 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 298.0
TLS2_k127_12518_4 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000001003 127.0
TLS2_k127_12518_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000008222 130.0
TLS2_k127_12518_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000005329 112.0
TLS2_k127_12518_8 Concanavalin A-like lectin/glucanases superfamily - - - 0.0004789 53.0
TLS2_k127_1255656_0 Sodium:neurotransmitter symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 603.0
TLS2_k127_1255656_1 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 441.0
TLS2_k127_1255656_10 Protein of unknown function (DUF1559) K02456 - - 0.0000000000004739 79.0
TLS2_k127_1255656_11 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000001712 53.0
TLS2_k127_1255656_12 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000003626 54.0
TLS2_k127_1255656_2 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 409.0
TLS2_k127_1255656_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 410.0
TLS2_k127_1255656_4 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 377.0
TLS2_k127_1255656_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 339.0
TLS2_k127_1255656_6 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 289.0
TLS2_k127_1255656_7 Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000000000000000000000000000000000000145 200.0
TLS2_k127_1255656_8 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000008785 184.0
TLS2_k127_1255656_9 cellulose binding - - - 0.000000000000000003824 99.0
TLS2_k127_1256269_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 477.0
TLS2_k127_1256269_1 SMP-30 Gluconolaconase LRE-like K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 378.0
TLS2_k127_1256269_2 ankyrin repeat K15502,K15503 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0070013 - 0.0000000000000000426 90.0
TLS2_k127_1261876_0 COG3119 Arylsulfatase A K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 463.0
TLS2_k127_1261876_1 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 307.0
TLS2_k127_1269244_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 9.057e-272 849.0
TLS2_k127_1269244_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 299.0
TLS2_k127_1269244_2 ChrR Cupin-like domain - - - 0.00003133 51.0
TLS2_k127_1285217_0 chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 387.0
TLS2_k127_1285217_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000007708 241.0
TLS2_k127_1285217_2 ABC transporter K02003,K05685 - - 0.000000000000000000001134 99.0
TLS2_k127_1288350_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000002099 149.0
TLS2_k127_1288350_2 sequence-specific DNA binding K03555,K16328 - 2.7.1.83 0.0000000000000000002048 93.0
TLS2_k127_1288350_3 sequence-specific DNA binding K03555,K16328 - 2.7.1.83 0.000000000000002193 84.0
TLS2_k127_1295660_0 efflux transmembrane transporter activity - - - 2.549e-239 757.0
TLS2_k127_1295660_1 NADH dehydrogenase K00333,K14090 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001505 192.0
TLS2_k127_1295660_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K14089 - - 0.00000000000000000004026 100.0
TLS2_k127_1295660_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K14091 - 1.6.5.3 0.0000000000468 64.0
TLS2_k127_1295660_4 Peptidase family M48 - - - 0.0000004722 51.0
TLS2_k127_1301856_0 heme-binding domain, Pirellula Verrucomicrobium type - - - 0.0 1043.0
TLS2_k127_1301856_1 L-lactate permease K03303 - - 6.331e-256 801.0
TLS2_k127_1301856_10 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000007929 75.0
TLS2_k127_1301856_11 Subtilase family K17734 - - 0.0000006545 63.0
TLS2_k127_1301856_2 oligopeptide transporter, OPT family - - - 3.378e-247 775.0
TLS2_k127_1301856_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 566.0
TLS2_k127_1301856_4 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000281 269.0
TLS2_k127_1301856_5 Domain of unknown function (4846) - - - 0.000000000000000000000000000000000000000000000000000000742 205.0
TLS2_k127_1301856_6 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000002608 208.0
TLS2_k127_1301856_7 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000005338 190.0
TLS2_k127_1301856_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000009596 145.0
TLS2_k127_1301856_9 - - - - 0.000000000000000000000000000008807 129.0
TLS2_k127_1303858_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 287.0
TLS2_k127_1303858_1 xylan catabolic process K01218,K03932,K19551 - 3.2.1.78,4.2.2.10,4.2.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000005423 252.0
TLS2_k127_1303858_2 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000001169 185.0
TLS2_k127_1305804_0 Aldolase K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 381.0
TLS2_k127_1305804_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008062 256.0
TLS2_k127_1305804_2 Transglutaminase-like superfamily - - - 0.000000001382 66.0
TLS2_k127_1305804_3 sigma-54 factor interaction domain-containing protein K07712 - - 0.000001265 51.0
TLS2_k127_1305804_4 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.00006273 56.0
TLS2_k127_1309574_0 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 455.0
TLS2_k127_1309574_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 338.0
TLS2_k127_1309574_10 - - - - 0.0000000000000003026 89.0
TLS2_k127_1309574_11 glycoprotease K14742 - - 0.000000000000003992 84.0
TLS2_k127_1309574_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 325.0
TLS2_k127_1309574_3 PFAM von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 344.0
TLS2_k127_1309574_4 von Willebrand factor type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 319.0
TLS2_k127_1309574_5 Acyl-CoA reductase (LuxC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002641 246.0
TLS2_k127_1309574_6 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000008383 229.0
TLS2_k127_1309574_7 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000001265 207.0
TLS2_k127_1309574_8 synthase K01737 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000002777 179.0
TLS2_k127_1309574_9 Oxygen tolerance - - - 0.00000000000000000003917 103.0
TLS2_k127_131141_0 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 480.0
TLS2_k127_131141_1 L-fucose isomerase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 449.0
TLS2_k127_131141_2 Cytochrome ba3-putative manganese transport protein mntH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 348.0
TLS2_k127_131141_3 PFAM FG-GAP repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 354.0
TLS2_k127_131141_4 Calx-beta domain K20276 - - 0.0000000000000000000000000000000000000000000000000007356 211.0
TLS2_k127_131141_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.000000000008122 72.0
TLS2_k127_1312497_0 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 323.0
TLS2_k127_1312497_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002939 282.0
TLS2_k127_1322425_0 type II secretion system protein E K02652 - - 4.246e-218 691.0
TLS2_k127_1322425_1 General secretory system II protein E domain protein K02454,K02652 - - 1.99e-208 662.0
TLS2_k127_1322425_10 glycosyl transferase family 8 - - - 0.000000000000003433 86.0
TLS2_k127_1322425_11 Type IV pilus biogenesis stability protein PilW - - - 0.000000001819 68.0
TLS2_k127_1322425_2 type II secretion K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 470.0
TLS2_k127_1322425_3 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 453.0
TLS2_k127_1322425_4 ABC transporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 389.0
TLS2_k127_1322425_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 342.0
TLS2_k127_1322425_6 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001295 260.0
TLS2_k127_1322425_7 Teichuronic acid biosynthesis glycosyltransferase tuaH K16699 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000139 209.0
TLS2_k127_1322425_8 - - - - 0.000000000000000000000000007413 128.0
TLS2_k127_1322425_9 glycosyl transferase family 2 - - - 0.000000000000000000000002608 109.0
TLS2_k127_1323477_0 Glycosyltransferase 36 associated - - - 0.0 2190.0
TLS2_k127_1323477_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.0 1089.0
TLS2_k127_1323477_2 ABC1 family K03688 - - 2.252e-244 766.0
TLS2_k127_1323477_3 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 534.0
TLS2_k127_1323477_4 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 479.0
TLS2_k127_1323477_5 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 363.0
TLS2_k127_1323477_6 amine dehydrogenase activity K01179,K03333,K12287 - 1.1.3.6,3.2.1.4 0.00000000000000000000000000000000002517 157.0
TLS2_k127_1323477_7 Pectate lyase superfamily protein - - - 0.0000000000000000000002891 114.0
TLS2_k127_1323477_8 - - - - 0.000000000000003123 76.0
TLS2_k127_1323477_9 Putative methyltransferase - - - 0.00000001528 63.0
TLS2_k127_1356262_0 polysaccharide deacetylase - - - 3.906e-221 709.0
TLS2_k127_1359051_0 AAA-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 378.0
TLS2_k127_1359051_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 300.0
TLS2_k127_1359051_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008427 302.0
TLS2_k127_1359051_3 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000001199 244.0
TLS2_k127_1366868_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 541.0
TLS2_k127_1366868_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 505.0
TLS2_k127_1366868_2 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005497 251.0
TLS2_k127_1366868_3 acid phosphatase activity K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000000227 255.0
TLS2_k127_1366868_4 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001493 232.0
TLS2_k127_1366868_5 NUDIX domain K03575 - - 0.000000000000000000000000001776 120.0
TLS2_k127_1366868_6 general secretion pathway protein K02456 - - 0.00000000000000005503 91.0
TLS2_k127_1375431_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 509.0
TLS2_k127_1375431_1 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003075 271.0
TLS2_k127_1375431_2 PFAM YD repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003227 248.0
TLS2_k127_1383630_0 CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000001378 189.0
TLS2_k127_1383630_1 PIN domain - - - 0.00000000000000000000000000000001365 131.0
TLS2_k127_1383630_2 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000004008 123.0
TLS2_k127_1383630_3 HicB family - - - 0.000000000000000003317 86.0
TLS2_k127_1383630_4 viral genome integration into host DNA - - - 0.000003976 53.0
TLS2_k127_1385868_0 Domain of unknown function (DUF4268) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005159 269.0
TLS2_k127_1385868_1 endonuclease activity - - - 0.000000000000000000000000000000000000000000001011 172.0
TLS2_k127_1385868_2 Belongs to the 'phage' integrase family - - - 0.00000000000001075 84.0
TLS2_k127_1388521_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 428.0
TLS2_k127_1388521_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000002607 138.0
TLS2_k127_1388521_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000005826 61.0
TLS2_k127_1405976_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000353 175.0
TLS2_k127_1405976_2 Translation initiation factor SUI1 K03113 - - 0.000000000000000000009795 94.0
TLS2_k127_1412657_0 nuclear-transcribed mRNA catabolic process, no-go decay - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 542.0
TLS2_k127_1412657_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000002292 181.0
TLS2_k127_1412657_2 - - - - 0.00000000000000000000000000000000000672 138.0
TLS2_k127_1412657_3 Ribosomal subunit interface protein - - - 0.00000000000000000000000000003715 119.0
TLS2_k127_1416282_0 Parallel beta-helix repeats - - - 1.091e-258 819.0
TLS2_k127_1416282_1 pyrroloquinoline quinone binding K01051 - 3.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 392.0
TLS2_k127_1416282_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000003951 192.0
TLS2_k127_1416282_3 Aldo/keto reductase family K07079 - - 0.0000000000000000000000000000000007083 143.0
TLS2_k127_1416282_4 - - - - 0.000000000000000000000000000000009808 134.0
TLS2_k127_1417913_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 6.319e-315 979.0
TLS2_k127_1417913_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 333.0
TLS2_k127_1417913_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000005001 124.0
TLS2_k127_1417913_11 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000002663 91.0
TLS2_k127_1417913_12 Ribosomal L29 protein K02904 - - 0.00003692 49.0
TLS2_k127_1417913_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 298.0
TLS2_k127_1417913_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000009108 226.0
TLS2_k127_1417913_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000001484 224.0
TLS2_k127_1417913_5 Ribosomal protein S7p/S5e K02992 - - 0.00000000000000000000000000000000000000000000000000000003571 199.0
TLS2_k127_1417913_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000008008 198.0
TLS2_k127_1417913_7 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000304 184.0
TLS2_k127_1417913_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000002529 168.0
TLS2_k127_1417913_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000001751 134.0
TLS2_k127_145929_0 - - - - 0.0000000000000000000000000000000000000000000000000000000002247 205.0
TLS2_k127_145929_1 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000004907 210.0
TLS2_k127_145929_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000906 76.0
TLS2_k127_145929_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000001164 57.0
TLS2_k127_1462478_0 Amidohydrolase family - - - 0.0 1060.0
TLS2_k127_1462478_1 Belongs to the glycosyl hydrolase 57 family K03406,K16149 - 2.4.1.18 1.389e-194 621.0
TLS2_k127_1462478_10 type VI secretion system effector K11903 - - 0.000000000000000000001048 104.0
TLS2_k127_1462478_11 PFAM Rho termination factor, N-terminal domain K09942 - - 0.00000000000000000001176 94.0
TLS2_k127_1462478_12 - - - - 0.00000000000000116 79.0
TLS2_k127_1462478_13 transposase activity K07483 - - 0.00000000000001066 76.0
TLS2_k127_1462478_14 Alginate export - - - 0.0000000005178 66.0
TLS2_k127_1462478_15 salt-induced outer membrane protein K07283 - - 0.0000002046 61.0
TLS2_k127_1462478_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 393.0
TLS2_k127_1462478_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 371.0
TLS2_k127_1462478_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000027 277.0
TLS2_k127_1462478_5 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002121 269.0
TLS2_k127_1462478_6 Antibiotic biosynthesis monooxygenase K09932 - - 0.0000000000000000000000000000000000000000000000000000000000000676 218.0
TLS2_k127_1462478_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000008089 220.0
TLS2_k127_1462478_8 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000122 218.0
TLS2_k127_1467606_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 9.41e-203 642.0
TLS2_k127_1467606_1 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 339.0
TLS2_k127_1493450_0 Proline dehydrogenase K13821 - 1.2.1.88,1.5.5.2 0.0 1456.0
TLS2_k127_1493450_1 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 527.0
TLS2_k127_1493450_2 lipolytic protein G-D-S-L family K01218 - 3.2.1.78 0.00000000000000000000000000000000000000000000000000000003487 213.0
TLS2_k127_1493450_3 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000003018 174.0
TLS2_k127_1493450_4 MobA-like NTP transferase domain - - - 0.00000000000000000000001997 108.0
TLS2_k127_1493450_5 SMART Immunoglobulin C2 type - - - 0.000631 52.0
TLS2_k127_1496891_0 Integrase core domain K07497 - - 0.000000000000000000000000000000000004531 146.0
TLS2_k127_1496891_1 transposase activity K07483,K07497 - - 0.000000000000000000000000000001192 123.0
TLS2_k127_1500198_0 cellulase activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000004198 249.0
TLS2_k127_1500198_1 Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000000000000000000000000000000000000002383 203.0
TLS2_k127_1500198_2 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000009248 169.0
TLS2_k127_1500198_3 peptidase activity, acting on L-amino acid peptides K07004,K09955,K12287 - - 0.0000000000000000000000000000007509 143.0
TLS2_k127_1500198_4 Belongs to the glycosyl hydrolase 2 family - - - 0.00000000000003211 88.0
TLS2_k127_1500198_5 regulator of chromosome condensation, RCC1 - - - 0.00000000005419 77.0
TLS2_k127_1510049_0 Nucleotidyltransferase DNA polymerase involved in DNA repair K03502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 421.0
TLS2_k127_1510049_1 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000005546 206.0
TLS2_k127_1510049_2 DDE domain K07498 - - 0.000000000000000000000000000000000000000000003917 166.0
TLS2_k127_1510049_3 Belongs to the peptidase S24 family K03503 - - 0.00000000000000000000000000000000000000000002685 166.0
TLS2_k127_1510049_4 COG3316 Transposase and inactivated derivatives K07498 - - 0.00000000000000000000000000002965 119.0
TLS2_k127_1510049_5 - - - - 0.0002073 50.0
TLS2_k127_1512669_0 L-fucose isomerase, C-terminal domain - - - 7.492e-208 659.0
TLS2_k127_1512669_1 COGs COG3533 conserved K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 519.0
TLS2_k127_1512669_2 ROK family K02565 - - 0.000000000000000000001188 105.0
TLS2_k127_1527608_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.079e-237 748.0
TLS2_k127_1527608_1 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 2.186e-217 704.0
TLS2_k127_1527608_10 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 344.0
TLS2_k127_1527608_11 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000393 211.0
TLS2_k127_1527608_12 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000001572 200.0
TLS2_k127_1527608_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000001861 196.0
TLS2_k127_1527608_14 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000004928 157.0
TLS2_k127_1527608_15 Membrane - - - 0.0000000000000002455 91.0
TLS2_k127_1527608_16 Sigma-70, region 4 - - - 0.0000000000006159 76.0
TLS2_k127_1527608_17 Yip1 domain - - - 0.000000001199 68.0
TLS2_k127_1527608_18 Bacterial flagellin N-terminal helical region K02397 - - 0.000000005175 60.0
TLS2_k127_1527608_19 Domain of unknown function (DUF4142) K08995 - - 0.0000002279 62.0
TLS2_k127_1527608_2 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 - 3.2.1.141 1.773e-210 671.0
TLS2_k127_1527608_20 Zinc-binding dehydrogenase - - - 0.000002014 51.0
TLS2_k127_1527608_3 PFAM Alcohol dehydrogenase - - - 5.733e-208 652.0
TLS2_k127_1527608_4 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 507.0
TLS2_k127_1527608_5 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 401.0
TLS2_k127_1527608_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 389.0
TLS2_k127_1527608_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 377.0
TLS2_k127_1527608_8 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 342.0
TLS2_k127_1527608_9 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 340.0
TLS2_k127_1529297_0 and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 348.0
TLS2_k127_1529297_1 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003451 243.0
TLS2_k127_1529297_2 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000001371 235.0
TLS2_k127_1529297_3 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor K10672,K10794 - 1.21.4.1,1.21.4.2 0.000000000000000000000000000000000000000000000000001202 196.0
TLS2_k127_1529297_4 - - - - 0.0000000000000006703 89.0
TLS2_k127_1529297_5 - - - - 0.00000000000006544 74.0
TLS2_k127_1529297_6 CDP-alcohol phosphatidyltransferase - - - 0.000003059 53.0
TLS2_k127_1548041_0 protein hemolysin III K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 353.0
TLS2_k127_1548041_1 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 340.0
TLS2_k127_1548041_3 - - - - 0.000000000000000000000000000000000000000001211 161.0
TLS2_k127_1548041_4 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000006431 132.0
TLS2_k127_1548041_5 oxidation-reduction process - - - 0.000006107 49.0
TLS2_k127_1548041_6 - - - - 0.0001569 48.0
TLS2_k127_1631672_0 peptidase activity K01286 - 3.4.16.4 0.00000000000000000000000000000000000002266 161.0
TLS2_k127_1631672_1 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000004836 152.0
TLS2_k127_1631672_2 GYD domain - - - 0.000000000000000000005627 96.0
TLS2_k127_1631672_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000005467 80.0
TLS2_k127_1634996_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 5.691e-277 862.0
TLS2_k127_1634996_1 Belongs to the ribulokinase family K00853 - 2.7.1.16 7.372e-226 713.0
TLS2_k127_1634996_2 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 6.37e-210 678.0
TLS2_k127_1634996_3 PFAM Alcohol dehydrogenase GroES domain protein K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 495.0
TLS2_k127_1634996_4 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 471.0
TLS2_k127_1634996_5 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 302.0
TLS2_k127_1634996_6 Prokaryotic N-terminal methylation motif - - - 0.0000000000009208 79.0
TLS2_k127_1658085_0 Serine hydrolase (FSH1) K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000003684 186.0
TLS2_k127_1658085_1 - - - - 0.000000000000000000000000000000000000000000000005685 179.0
TLS2_k127_1660067_0 PFAM Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 425.0
TLS2_k127_1660067_1 Polysaccharide deacetylase - - - 0.00000001026 66.0
TLS2_k127_1665391_0 negative regulation of protein lipidation K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 462.0
TLS2_k127_1665391_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 444.0
TLS2_k127_1665391_10 O-Antigen ligase - - - 0.0000000000000000000000000000000000005414 160.0
TLS2_k127_1665391_11 Glycosyl hydrolase family 10 - - - 0.00000000000000000000000000000004854 135.0
TLS2_k127_1665391_12 general secretion pathway protein - - - 0.00000000000000000003923 98.0
TLS2_k127_1665391_13 glycogen (starch) synthase activity - - - 0.0000000000000000002289 101.0
TLS2_k127_1665391_14 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000003148 95.0
TLS2_k127_1665391_15 - - - - 0.0000000000002105 83.0
TLS2_k127_1665391_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 304.0
TLS2_k127_1665391_3 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 308.0
TLS2_k127_1665391_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007414 290.0
TLS2_k127_1665391_5 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000007667 246.0
TLS2_k127_1665391_6 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000007557 182.0
TLS2_k127_1665391_7 SGNH hydrolase-like domain, acetyltransferase AlgX K19295 - - 0.0000000000000000000000000000000000000000003489 173.0
TLS2_k127_1665391_8 PFAM Glycosyl transferase, group 1 K12994 - 2.4.1.349 0.00000000000000000000000000000000000000115 161.0
TLS2_k127_1665391_9 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000002747 160.0
TLS2_k127_1683266_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 387.0
TLS2_k127_1683266_1 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 376.0
TLS2_k127_1683266_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000003381 243.0
TLS2_k127_1683266_3 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000002612 162.0
TLS2_k127_1683266_4 MacB-like periplasmic core domain - - - 0.0000000000000000000000000001454 123.0
TLS2_k127_1720268_0 Beta-eliminating lyase K01667 - 4.1.99.1 9.277e-207 653.0
TLS2_k127_1720268_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 625.0
TLS2_k127_1720268_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000001507 167.0
TLS2_k127_1720268_11 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000000000000009055 137.0
TLS2_k127_1720268_12 Belongs to the UPF0312 family - - - 0.000000000000000003482 93.0
TLS2_k127_1720268_13 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000281 72.0
TLS2_k127_1720268_14 general secretion pathway protein K02456 - - 0.000006919 58.0
TLS2_k127_1720268_15 (FHA) domain - - - 0.00001881 53.0
TLS2_k127_1720268_2 helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 479.0
TLS2_k127_1720268_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 410.0
TLS2_k127_1720268_4 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 373.0
TLS2_k127_1720268_5 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 364.0
TLS2_k127_1720268_6 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K08641,K11206 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 336.0
TLS2_k127_1720268_7 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 297.0
TLS2_k127_1720268_8 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 287.0
TLS2_k127_1720268_9 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000001015 219.0
TLS2_k127_173345_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 355.0
TLS2_k127_173345_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 338.0
TLS2_k127_173345_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.00000000000000000000000000000000004059 137.0
TLS2_k127_173400_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 2.286e-307 952.0
TLS2_k127_173400_1 Insecticidal toxin complex - - - 5.735e-223 769.0
TLS2_k127_173400_2 Protein of unknown function (DUF4038) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 530.0
TLS2_k127_173400_3 protein histidine kinase activity K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 357.0
TLS2_k127_173400_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000001062 239.0
TLS2_k127_173400_5 - - - - 0.00000000000000000000000000000000000000000000000000000000002872 216.0
TLS2_k127_173400_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000002106 166.0
TLS2_k127_173400_7 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000001249 92.0
TLS2_k127_173400_8 COG3209 Rhs family protein - - - 0.000000000000001979 93.0
TLS2_k127_1768660_0 Type II restriction enzyme, methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 494.0
TLS2_k127_1768660_1 type II restriction enzyme, methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 443.0
TLS2_k127_1768660_2 HAF family - - - 0.0000000000000000000000000000000000000000000000000000006291 208.0
TLS2_k127_1768660_3 nucleoside 2-deoxyribosyltransferase - - - 0.000000000000000000000000000000000000000000001624 177.0
TLS2_k127_17865_0 peptidyl-tyrosine sulfation - - - 8.922e-283 897.0
TLS2_k127_17865_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 340.0
TLS2_k127_17865_10 Endonuclease/Exonuclease/phosphatase family - - - 0.0008741 42.0
TLS2_k127_17865_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 299.0
TLS2_k127_17865_3 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000003879 231.0
TLS2_k127_17865_4 PFAM Uncharacterised protein family UPF0066 K01628 - 4.1.2.17 0.000000000000000000000000000000000000008293 156.0
TLS2_k127_17865_5 3-methyl-2-oxobutanoate hydroxymethyltransferase activity K00606 - 2.1.2.11 0.000000000000000000000000000122 115.0
TLS2_k127_17865_6 CoA binding domain K06929 - - 0.000000000000000000000002285 108.0
TLS2_k127_17865_7 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000006902 70.0
TLS2_k127_17865_8 peptidase M4 thermolysin K01399,K08604 GO:0005575,GO:0005576 3.4.24.25,3.4.24.26 0.0000001453 59.0
TLS2_k127_17865_9 Ferritin-like domain K03594 - 1.16.3.1 0.0004395 45.0
TLS2_k127_1788678_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1130.0
TLS2_k127_1788678_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.698e-245 770.0
TLS2_k127_1788678_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 540.0
TLS2_k127_1788678_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 404.0
TLS2_k127_1788678_4 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 360.0
TLS2_k127_1788678_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008179 373.0
TLS2_k127_1798659_0 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 392.0
TLS2_k127_1798659_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000389 252.0
TLS2_k127_1798659_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves - - - 0.0000000000000000000000000000000000000000000000000000000000000004398 230.0
TLS2_k127_1798659_3 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000009147 176.0
TLS2_k127_1798659_4 Segregation and condensation complex subunit ScpB - - - 0.00000000000000000000000000000000000000002672 163.0
TLS2_k127_1806476_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 571.0
TLS2_k127_1806476_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 529.0
TLS2_k127_1806476_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000004994 92.0
TLS2_k127_1806476_2 PFAM oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 521.0
TLS2_k127_1806476_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 361.0
TLS2_k127_1806476_4 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 341.0
TLS2_k127_1806476_5 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 304.0
TLS2_k127_1806476_6 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 299.0
TLS2_k127_1806476_7 Arylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000343 267.0
TLS2_k127_1806476_8 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000002714 151.0
TLS2_k127_1806476_9 TIGRFAM phosphocarrier, HPr family K11189 - - 0.0000000000000000000000000000001566 126.0
TLS2_k127_181609_0 xyloglucan:xyloglucosyl transferase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 494.0
TLS2_k127_181609_1 - - - - 0.0000000000000000000000000000000000001688 149.0
TLS2_k127_181609_2 beta-propeller repeat - - - 0.00000000000005925 72.0
TLS2_k127_1842632_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 547.0
TLS2_k127_1842632_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.000000000000000000000000000000000000000000002199 183.0
TLS2_k127_1842632_2 Polysaccharide pyruvyl transferase - - - 0.0000000000000000000000000000000000000006489 162.0
TLS2_k127_1842632_3 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000001356 143.0
TLS2_k127_1852337_0 COG3119 Arylsulfatase A K01134 - 3.1.6.8 6.557e-237 738.0
TLS2_k127_1852337_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 411.0
TLS2_k127_1852337_2 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000002123 83.0
TLS2_k127_1852337_3 4-amino-4-deoxy-L-arabinose transferase activity K00728 - 2.4.1.109 0.0000000000007269 78.0
TLS2_k127_1852337_4 COG3119 Arylsulfatase A - - - 0.00001815 49.0
TLS2_k127_1885676_0 TIGRFAM amino acid carrier protein K03310 - - 6.67e-207 655.0
TLS2_k127_1885676_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 609.0
TLS2_k127_1885676_2 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 534.0
TLS2_k127_1885676_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 323.0
TLS2_k127_1885676_4 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000000000000000003555 229.0
TLS2_k127_1885676_5 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000001198 233.0
TLS2_k127_1885676_6 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000000000007883 209.0
TLS2_k127_1885676_7 Beta-lactamase - - - 0.00003569 48.0
TLS2_k127_1889347_0 Cytochrome c554 and c-prime - - - 2.894e-226 724.0
TLS2_k127_1889347_1 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 569.0
TLS2_k127_1889347_10 guanyl-nucleotide exchange factor activity - - - 0.000000000000000000000000000000063 145.0
TLS2_k127_1889347_11 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000001443 115.0
TLS2_k127_1889347_12 GntR family K07979 - - 0.0000000000000000000002366 102.0
TLS2_k127_1889347_13 DNA methylase K03427 - 2.1.1.72 0.00000006013 61.0
TLS2_k127_1889347_14 FUN14 family - - - 0.0000001488 62.0
TLS2_k127_1889347_15 PFAM ATP-binding region ATPase domain protein - - - 0.00001817 49.0
TLS2_k127_1889347_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 528.0
TLS2_k127_1889347_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 474.0
TLS2_k127_1889347_4 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 445.0
TLS2_k127_1889347_5 Protein of unknown function (DUF1593) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 445.0
TLS2_k127_1889347_6 transketolase activity K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 414.0
TLS2_k127_1889347_7 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 372.0
TLS2_k127_1889347_8 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 351.0
TLS2_k127_1889347_9 ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000004004 205.0
TLS2_k127_1890272_0 cell wall glycoprotein biosynthetic process - - - 5.507e-233 736.0
TLS2_k127_1890272_1 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 347.0
TLS2_k127_1890272_2 UTRA K03710,K10711 - - 0.00000000000000000000000000000000000000000000000000000000000000006317 231.0
TLS2_k127_1890272_3 Glucose-6-phosphate isomerase (GPI) - - - 0.000000000000000000000000000000000000000000000000000008644 196.0
TLS2_k127_1890272_4 Cupin 2, conserved barrel domain protein K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000001567 179.0
TLS2_k127_1892051_0 PFAM phosphate acetyl butaryl transferase K00625,K13788 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 402.0
TLS2_k127_1892051_1 DRTGG domain K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 394.0
TLS2_k127_1892051_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 386.0
TLS2_k127_1892051_3 Amino acid kinase family - - - 0.0000000000000000000000000000000000000000000000000000003708 196.0
TLS2_k127_1892051_4 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000002209 156.0
TLS2_k127_1892051_5 PFAM Cytochrome c assembly protein - - - 0.0000000000000000002397 97.0
TLS2_k127_1904163_0 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000002201 230.0
TLS2_k127_1904163_1 PIN domain - - - 0.00000000000004111 75.0
TLS2_k127_1910462_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1229.0
TLS2_k127_1910462_1 sigma-54 factor interaction domain-containing protein - - - 1.025e-200 634.0
TLS2_k127_1910462_10 - K13640 - - 0.0000000000000000001439 93.0
TLS2_k127_1910462_11 - - - - 0.00000000000000002035 96.0
TLS2_k127_1910462_12 - - - - 0.000000000000000888 81.0
TLS2_k127_1910462_13 COG0457 FOG TPR repeat - - - 0.00000000003873 72.0
TLS2_k127_1910462_14 SNF2 family N-terminal domain - - - 0.0000000001828 69.0
TLS2_k127_1910462_15 ABC-2 family transporter protein - - - 0.0000000002044 71.0
TLS2_k127_1910462_16 antisigma factor binding K04749,K06378 - - 0.00000007713 60.0
TLS2_k127_1910462_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 533.0
TLS2_k127_1910462_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 292.0
TLS2_k127_1910462_4 ABC-type multidrug transport system ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000012 241.0
TLS2_k127_1910462_5 Belongs to the glycosyl hydrolase 28 family - - - 0.00000000000000000000000000000000000000000000000000000000000000005528 243.0
TLS2_k127_1910462_6 - - - - 0.000000000000000000000000000000004909 138.0
TLS2_k127_1910462_7 Sucrose-6F-phosphate phosphohydrolase - - - 0.000000000000000000000000002173 118.0
TLS2_k127_1910462_8 - - - - 0.00000000000000000000000009121 110.0
TLS2_k127_1910462_9 Histidine kinase-like ATPase domain - - - 0.0000000000000000000002476 106.0
TLS2_k127_1925860_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 600.0
TLS2_k127_1925860_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 498.0
TLS2_k127_1925860_10 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000004731 149.0
TLS2_k127_1925860_11 von Willebrand factor, type A - - - 0.00000000000000000000000001913 127.0
TLS2_k127_1925860_12 transmembrane transport - - - 0.00000000000002006 87.0
TLS2_k127_1925860_13 - - - - 0.000000002321 70.0
TLS2_k127_1925860_14 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000006609 57.0
TLS2_k127_1925860_2 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 434.0
TLS2_k127_1925860_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 424.0
TLS2_k127_1925860_4 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 386.0
TLS2_k127_1925860_5 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 362.0
TLS2_k127_1925860_6 Homeodomain-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 308.0
TLS2_k127_1925860_7 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 327.0
TLS2_k127_1925860_8 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 296.0
TLS2_k127_1925860_9 Stress responsive A/B Barrel Domain - - - 0.00000000000000000000000000000000000009731 146.0
TLS2_k127_1941294_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.577e-261 819.0
TLS2_k127_1941294_1 Acetyl xylan esterase (AXE1) - - - 3.608e-233 743.0
TLS2_k127_1941294_10 Binds the 23S rRNA K02909 - - 0.000000000000000000007204 100.0
TLS2_k127_1941294_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 402.0
TLS2_k127_1941294_3 PFAM Orn DAP Arg decarboxylase 2 K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 358.0
TLS2_k127_1941294_4 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 337.0
TLS2_k127_1941294_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000005705 252.0
TLS2_k127_1941294_6 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000002362 226.0
TLS2_k127_1941294_7 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000001117 211.0
TLS2_k127_1941294_8 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.00000000000000000000000000000000000000000000000000000732 196.0
TLS2_k127_1941294_9 solute sodium symporter, small subunit - - - 0.000000000000000000000000000003225 122.0
TLS2_k127_1942262_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 1.258e-201 638.0
TLS2_k127_1942262_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 584.0
TLS2_k127_1942262_2 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 428.0
TLS2_k127_1942262_3 ThiC-associated domain K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 292.0
TLS2_k127_1942262_4 Histidinol phosphatase and related hydrolases of the PHP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002287 267.0
TLS2_k127_1942262_5 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000001429 232.0
TLS2_k127_1942262_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000005213 166.0
TLS2_k127_1942262_7 Pilus assembly protein PilX - - - 0.00000000000000000000000000007664 133.0
TLS2_k127_1942262_8 Pilus assembly protein K02461,K02662 - - 0.00000000000000000000001056 117.0
TLS2_k127_1946701_0 Proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 486.0
TLS2_k127_1946701_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001984 266.0
TLS2_k127_1946701_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000001615 98.0
TLS2_k127_1947349_0 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 544.0
TLS2_k127_1947349_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 519.0
TLS2_k127_1947349_2 SMART helicase c2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 378.0
TLS2_k127_1947349_3 - - - - 0.00000000000000000000000000000000000000000001206 172.0
TLS2_k127_1947349_4 response to abiotic stimulus - - - 0.00000000000000000000000004343 108.0
TLS2_k127_1947349_5 amine dehydrogenase activity - - - 0.00000000013 63.0
TLS2_k127_1947349_6 Protein of unknown function (DUF1232) - - - 0.00000001536 63.0
TLS2_k127_1971075_0 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 582.0
TLS2_k127_1971075_1 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007119 269.0
TLS2_k127_1971075_2 Penicillin binding protein transpeptidase domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000002244 214.0
TLS2_k127_1986897_0 Belongs to the 5'-nucleotidase family - - - 2.173e-207 655.0
TLS2_k127_1986897_1 Sulfate transporter K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 471.0
TLS2_k127_1986897_2 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 403.0
TLS2_k127_1986897_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 291.0
TLS2_k127_1986897_4 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000003163 225.0
TLS2_k127_1991011_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 389.0
TLS2_k127_1991011_1 RHS repeat-associated core domain protein - - - 0.0000000000000000000000000000000000000000000000000000004755 222.0
TLS2_k127_1995386_0 Oxaloacetate decarboxylase, alpha subunit K01571,K01960 - 4.1.1.3,6.4.1.1 2.362e-240 770.0
TLS2_k127_1995386_1 response to abiotic stimulus - - - 6.3e-239 749.0
TLS2_k127_1995386_10 Protein of unknown function (DUF3788) - - - 0.000000000000000000000000000001512 126.0
TLS2_k127_1995386_11 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000002303 114.0
TLS2_k127_1995386_12 Protein of unknown function (DUF541) K09797 - - 0.000006735 53.0
TLS2_k127_1995386_14 Protein of unknown function (DUF541) K09797 - - 0.0004634 50.0
TLS2_k127_1995386_2 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 481.0
TLS2_k127_1995386_3 response to abiotic stimulus K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 396.0
TLS2_k127_1995386_5 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001515 278.0
TLS2_k127_1995386_6 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004177 295.0
TLS2_k127_1995386_7 transferase activity, transferring acyl groups other than amino-acyl groups K11941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005185 278.0
TLS2_k127_1995386_8 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000005991 216.0
TLS2_k127_1995386_9 PFAM Biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000009435 135.0
TLS2_k127_1997810_0 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 377.0
TLS2_k127_1997810_1 Phospholipase/Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000003548 194.0
TLS2_k127_1997810_2 cellulase activity - - - 0.00000000000000000000000000000000000000001303 165.0
TLS2_k127_1997810_3 - - - - 0.0000000000000000000000000000003046 140.0
TLS2_k127_1997810_4 general secretion pathway protein K02456,K02679 - - 0.0000000000004268 79.0
TLS2_k127_1997810_5 Nacht domain - - - 0.00009476 53.0
TLS2_k127_2009325_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1344.0
TLS2_k127_2009325_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 293.0
TLS2_k127_2009325_2 Squalene/phytoene synthase K00801,K02291,K10208 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000002346 259.0
TLS2_k127_2009325_3 - - - - 0.00000000000000000000000000000000006041 143.0
TLS2_k127_2009325_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000376 123.0
TLS2_k127_2009325_5 - - - - 0.00000000000000000000000003347 112.0
TLS2_k127_2028762_0 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 441.0
TLS2_k127_2028762_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001519 220.0
TLS2_k127_2035090_0 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 403.0
TLS2_k127_2035090_1 mannitol 2-dehydrogenase activity K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001541 267.0
TLS2_k127_2035090_2 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000001294 216.0
TLS2_k127_2035090_3 quinolinate synthetase A activity K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000119 114.0
TLS2_k127_2035090_4 transposition K07497 - - 0.00000000000000001369 85.0
TLS2_k127_2035090_5 - - - - 0.0000000000000009478 77.0
TLS2_k127_2035090_6 DNA-templated transcription, initiation K03088 - - 0.000000000000007021 83.0
TLS2_k127_2035090_7 pyrroloquinoline quinone binding K01179 - 3.2.1.4 0.00000000002638 78.0
TLS2_k127_206777_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 301.0
TLS2_k127_206777_1 - - - - 0.0000000000000000000000000000000000000000000000000000000725 205.0
TLS2_k127_206777_2 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000000000001973 120.0
TLS2_k127_206777_3 - - - - 0.000000000000000003774 97.0
TLS2_k127_2067901_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.894e-282 876.0
TLS2_k127_2067901_1 tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 505.0
TLS2_k127_2067901_10 Signal transduction histidine kinase, LytS K02478 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001867 224.0
TLS2_k127_2067901_11 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000008924 216.0
TLS2_k127_2067901_12 dTDP-4-dehydrorhamnose 3,5-epimerase activity K19068 - 1.1.1.367 0.0000000000000000000000000000000000003705 143.0
TLS2_k127_2067901_13 - - - - 0.0000000000000001644 84.0
TLS2_k127_2067901_14 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000619 61.0
TLS2_k127_2067901_2 Oxidoreductase family, NAD-binding Rossmann fold K00118,K13020 - 1.1.1.335,1.1.99.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 440.0
TLS2_k127_2067901_3 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 390.0
TLS2_k127_2067901_4 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 345.0
TLS2_k127_2067901_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 325.0
TLS2_k127_2067901_6 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 316.0
TLS2_k127_2067901_7 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 292.0
TLS2_k127_2067901_8 Glycosyl hydrolases family 43 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005956 241.0
TLS2_k127_2067901_9 CorA-like Mg2+ transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001276 242.0
TLS2_k127_2091967_0 Domain of unknown function (DUF5060) - - - 1.705e-309 977.0
TLS2_k127_2091967_1 Glycosyl hydrolase, family 20, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 557.0
TLS2_k127_2091967_2 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 303.0
TLS2_k127_2091967_3 Astacin (Peptidase family M12A) - - - 0.00000000000000000000000000000000000000000000000000000000001827 216.0
TLS2_k127_209672_0 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000001321 170.0
TLS2_k127_209672_1 SMART Tetratricopeptide - - - 0.000002548 59.0
TLS2_k127_209672_2 metallopeptidase activity K07762,K08647 GO:0000003,GO:0001558,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0006508,GO:0006807,GO:0007565,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016787,GO:0019538,GO:0022414,GO:0031960,GO:0032501,GO:0033993,GO:0040008,GO:0042221,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044703,GO:0044706,GO:0046872,GO:0046914,GO:0048545,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051384,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.24.79 0.00003759 52.0
TLS2_k127_2101752_0 formate dehydrogenase - - - 1.547e-320 996.0
TLS2_k127_2101752_1 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 602.0
TLS2_k127_2101752_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 559.0
TLS2_k127_2101752_3 Phospholipase D Transphosphatidylase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 550.0
TLS2_k127_2101752_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000001393 224.0
TLS2_k127_2101752_5 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000004623 169.0
TLS2_k127_2101752_6 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000002462 166.0
TLS2_k127_2101752_7 COG0668 Small-conductance mechanosensitive channel - - - 0.0000000000000000000000000000000001836 137.0
TLS2_k127_2101752_8 - - - - 0.000000000003747 75.0
TLS2_k127_2101752_9 Putative glucoamylase - - - 0.00000000001677 66.0
TLS2_k127_2102356_0 PQQ-like domain - - - 2.052e-219 693.0
TLS2_k127_2102356_1 PQQ-like domain - - - 7.505e-201 651.0
TLS2_k127_2102356_10 Putative regulatory protein - - - 0.0000000000000000000000000001251 122.0
TLS2_k127_2102356_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000001267 99.0
TLS2_k127_2102356_12 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000006309 88.0
TLS2_k127_2102356_13 sulfurtransferase - - - 0.0000000000000001141 81.0
TLS2_k127_2102356_15 Prokaryotic N-terminal methylation motif - - - 0.000000000000001017 88.0
TLS2_k127_2102356_16 cellulase activity K01081,K01179,K06931 - 3.1.3.5,3.2.1.4 0.00000000000002192 86.0
TLS2_k127_2102356_17 Protein of unknown function (DUF3311) - - - 0.00000000001283 68.0
TLS2_k127_2102356_18 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000004357 69.0
TLS2_k127_2102356_19 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000001204 63.0
TLS2_k127_2102356_2 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 425.0
TLS2_k127_2102356_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 417.0
TLS2_k127_2102356_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 334.0
TLS2_k127_2102356_6 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001363 253.0
TLS2_k127_2102356_7 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000004249 243.0
TLS2_k127_2102356_8 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000118 184.0
TLS2_k127_2102356_9 DNA-binding transcription factor activity K06075,K22296 - - 0.0000000000000000000000000000000000000000000424 168.0
TLS2_k127_2119145_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 498.0
TLS2_k127_2119145_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002718 279.0
TLS2_k127_2119145_2 cytochrome c nitrite reductase K15876 - - 0.000000000000000000000000000000000000000000000000000000001621 207.0
TLS2_k127_2119145_3 Pfam:DUF59 - - - 0.00000000000000000000000000000000000000000000000000000008148 200.0
TLS2_k127_2119145_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000001403 199.0
TLS2_k127_211975_0 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000008573 188.0
TLS2_k127_211975_1 PFAM Archaeal ATPase - - - 0.0000000000000008578 89.0
TLS2_k127_211975_2 beta-galactosidase activity - - - 0.000000000000001146 89.0
TLS2_k127_2123010_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 535.0
TLS2_k127_2123010_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 521.0
TLS2_k127_2123010_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 478.0
TLS2_k127_2123010_3 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001183 278.0
TLS2_k127_2123010_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000007301 164.0
TLS2_k127_2123010_5 - - - - 0.000000000000000000000000000000002105 149.0
TLS2_k127_2123010_6 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000006912 59.0
TLS2_k127_2129273_0 Belongs to the glycosyl hydrolase 28 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 465.0
TLS2_k127_2129273_1 Beta-propeller repeat - - - 0.0000000000005696 82.0
TLS2_k127_2138316_0 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 371.0
TLS2_k127_2138316_1 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 349.0
TLS2_k127_2138316_2 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009002 360.0
TLS2_k127_2138316_3 Glucose / Sorbosone dehydrogenase K00428,K01728 - 1.11.1.5,4.2.2.2 0.000000000000000000001816 112.0
TLS2_k127_2138316_4 ABC transporter K10545,K10562 - 3.6.3.17 0.0000000000000326 74.0
TLS2_k127_2138316_5 general secretion pathway protein - - - 0.0001175 47.0
TLS2_k127_2144593_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 476.0
TLS2_k127_2144593_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001364 272.0
TLS2_k127_2147224_0 Peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 586.0
TLS2_k127_2147224_1 hydroxyacid-oxoacid transhydrogenase activity K00001,K01714 - 1.1.1.1,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 428.0
TLS2_k127_2147224_2 NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000006633 208.0
TLS2_k127_2147224_3 Protein of unknown function (DUF721) - - - 0.0000000008645 67.0
TLS2_k127_2150351_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.235e-293 919.0
TLS2_k127_2150351_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 396.0
TLS2_k127_2150351_2 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 349.0
TLS2_k127_2150351_3 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001445 275.0
TLS2_k127_2150351_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000007483 178.0
TLS2_k127_2150351_5 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000000262 169.0
TLS2_k127_2165497_0 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 603.0
TLS2_k127_2165497_1 Na H antiporter MnhB subunit-related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 495.0
TLS2_k127_2165497_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000722 253.0
TLS2_k127_2165497_3 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000001395 185.0
TLS2_k127_2165497_4 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.000000000000000000000000000000000000000000000003566 179.0
TLS2_k127_2165497_5 Na+/H+ ion antiporter subunit K05569 - - 0.0000000000000000000000000000000000001545 148.0
TLS2_k127_2165497_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000000000001052 141.0
TLS2_k127_2165497_7 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000001141 98.0
TLS2_k127_2165497_8 Multiple resistance and pH regulation protein F (MrpF / PhaF) - - - 0.00000000000000000000447 97.0
TLS2_k127_217844_0 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 384.0
TLS2_k127_217844_1 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 364.0
TLS2_k127_217844_10 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000002596 85.0
TLS2_k127_217844_11 PFAM LysM domain - - - 0.00000000000001278 83.0
TLS2_k127_217844_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 357.0
TLS2_k127_217844_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 333.0
TLS2_k127_217844_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 308.0
TLS2_k127_217844_5 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001514 283.0
TLS2_k127_217844_6 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002513 266.0
TLS2_k127_217844_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000009345 258.0
TLS2_k127_217844_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000005141 223.0
TLS2_k127_217844_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000009914 153.0
TLS2_k127_2189116_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000265 141.0
TLS2_k127_2189116_1 Alternative locus ID - - - 0.000000001313 60.0
TLS2_k127_2208620_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 447.0
TLS2_k127_2208620_1 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000001724 250.0
TLS2_k127_2208620_2 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000005219 220.0
TLS2_k127_2208620_3 stress-induced mitochondrial fusion - - - 0.000000000000002366 86.0
TLS2_k127_2208620_4 - K01992,K16919 - - 0.00000000000002522 85.0
TLS2_k127_2208620_5 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase - - - 0.0000008455 51.0
TLS2_k127_2217929_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.491e-227 722.0
TLS2_k127_2217929_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 9.451e-223 706.0
TLS2_k127_2217929_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 411.0
TLS2_k127_2217929_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 391.0
TLS2_k127_2217929_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000003975 221.0
TLS2_k127_2217929_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000005479 205.0
TLS2_k127_2217929_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000004475 173.0
TLS2_k127_2217929_7 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000001556 160.0
TLS2_k127_2217929_8 Bacterial protein of unknown function (DUF883) - - - 0.00000000000003517 76.0
TLS2_k127_2217929_9 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000006102 62.0
TLS2_k127_22408_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 497.0
TLS2_k127_22408_1 SIS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 377.0
TLS2_k127_22408_2 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 324.0
TLS2_k127_22408_3 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 325.0
TLS2_k127_22408_4 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
TLS2_k127_22408_5 histidine kinase HAMP region domain protein K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000005475 204.0
TLS2_k127_22408_6 Response regulator, receiver - - - 0.00000000000000000000000000000000123 135.0
TLS2_k127_22408_7 Pseudouridine synthase K06177,K06179,K06180 - 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.0000000000000000000000000004049 126.0
TLS2_k127_22408_8 Methane oxygenase PmoA - - - 0.000000000000000000000002504 111.0
TLS2_k127_2241768_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 528.0
TLS2_k127_2241768_1 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 460.0
TLS2_k127_2241768_2 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 364.0
TLS2_k127_2252230_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1236.0
TLS2_k127_2252230_1 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 1.735e-260 823.0
TLS2_k127_2252230_2 heme-binding domain, Pirellula Verrucomicrobium type - - - 1.328e-248 794.0
TLS2_k127_2252230_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 319.0
TLS2_k127_2252230_4 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001729 294.0
TLS2_k127_2252230_5 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007693 285.0
TLS2_k127_2252230_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004824 273.0
TLS2_k127_2252230_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000006329 147.0
TLS2_k127_2252230_8 COGs COG2993 Cbb3-type cytochrome oxidase cytochrome c subunit K00405 - - 0.000000000000000000000000000002665 134.0
TLS2_k127_2252230_9 - - - - 0.0000005346 59.0
TLS2_k127_2259662_0 heme-binding domain, Pirellula Verrucomicrobium type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006891 460.0
TLS2_k127_2259662_1 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
TLS2_k127_2259662_2 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002672 263.0
TLS2_k127_2259662_3 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004136 254.0
TLS2_k127_2259662_4 cytochrome - - - 0.00000000000000000000000000000000000000000000000000002678 214.0
TLS2_k127_2259662_5 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000001977 151.0
TLS2_k127_2259662_6 Protein of unknown function (DUF3795) - - - 0.0000000000000000000001551 107.0
TLS2_k127_2259662_7 cellulose binding - - - 0.00000000000001803 78.0
TLS2_k127_2259662_8 PFAM PBS lyase HEAT-like repeat - - - 0.000000577 61.0
TLS2_k127_2265631_0 Zinc carboxypeptidase - - - 2.336e-277 881.0
TLS2_k127_2265631_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 508.0
TLS2_k127_2265631_2 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 368.0
TLS2_k127_2265631_3 Domain of unknown function (DUF5060) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 314.0
TLS2_k127_2268370_0 lipolytic protein G-D-S-L family - - - 3.274e-208 687.0
TLS2_k127_2268370_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 599.0
TLS2_k127_2268370_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 316.0
TLS2_k127_2268370_11 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000003366 177.0
TLS2_k127_2268370_12 beta-lactamase - - - 0.0000000000000000000000000000000000000000000005093 176.0
TLS2_k127_2268370_13 - - - - 0.000000000000000000000000000000000000000001436 160.0
TLS2_k127_2268370_14 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000006157 141.0
TLS2_k127_2268370_15 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000005881 76.0
TLS2_k127_2268370_16 Pectate lyase superfamily protein - - - 0.000000000000253 72.0
TLS2_k127_2268370_17 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000002728 77.0
TLS2_k127_2268370_18 general secretion pathway protein K02456,K02679 - - 0.00000000001446 74.0
TLS2_k127_2268370_19 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0001411 45.0
TLS2_k127_2268370_2 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 492.0
TLS2_k127_2268370_20 nucleic acid-binding protein, contains PIN domain - - - 0.0001697 46.0
TLS2_k127_2268370_3 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 456.0
TLS2_k127_2268370_4 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 432.0
TLS2_k127_2268370_5 DHHA1 domain K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 402.0
TLS2_k127_2268370_6 FAD dependent oxidoreductase K15736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 379.0
TLS2_k127_2268370_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 367.0
TLS2_k127_2268370_8 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 346.0
TLS2_k127_2268370_9 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 330.0
TLS2_k127_2268987_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18299,K18902 - - 0.0 1516.0
TLS2_k127_227182_0 Heavy metal translocating P-type atpase K01534,K17686 - 3.6.3.3,3.6.3.5,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 409.0
TLS2_k127_227182_1 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000006738 190.0
TLS2_k127_227182_2 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000001881 150.0
TLS2_k127_227182_3 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000001088 129.0
TLS2_k127_2284975_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002909 284.0
TLS2_k127_2284975_1 Pirin K06911 - - 0.000000000000000000000000001094 115.0
TLS2_k127_2284975_2 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000009591 96.0
TLS2_k127_2284975_3 Protein of unknown function (DUF3179) - - - 0.000000000000000006889 97.0
TLS2_k127_2284975_4 Sulfatase K01130 - 3.1.6.1 0.0000002148 59.0
TLS2_k127_2284975_5 Belongs to the pirin family K06911 GO:0003674,GO:0003824,GO:0008127,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0051213,GO:0055114 - 0.0000007238 51.0
TLS2_k127_2292278_0 pyrroloquinoline quinone binding K12349 - 3.5.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 603.0
TLS2_k127_2292278_1 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001531 266.0
TLS2_k127_2292278_2 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000009718 85.0
TLS2_k127_2292278_3 Protein of unknown function (DUF1587) - - - 0.000000000000002594 79.0
TLS2_k127_2292278_4 Toxic component of a toxin-antitoxin (TA) module - - - 0.000000001675 63.0
TLS2_k127_2292278_5 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000001552 59.0
TLS2_k127_2292278_6 RelB antitoxin - - - 0.000001376 57.0
TLS2_k127_2292278_7 Protein of unknown function (DUF1587) - - - 0.00007388 50.0
TLS2_k127_2293762_0 FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 391.0
TLS2_k127_2293762_1 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000006994 180.0
TLS2_k127_2293762_2 SpoIIAA-like - - - 0.0000000000000000000000000000000000000000000007997 168.0
TLS2_k127_2293762_3 PFAM Rieske 2Fe-2S domain protein - - - 0.0000000000000000000000000001225 122.0
TLS2_k127_2302562_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.504e-216 685.0
TLS2_k127_2302562_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 423.0
TLS2_k127_2302562_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 396.0
TLS2_k127_2302562_3 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 355.0
TLS2_k127_2302562_4 Glycosyltransferase family 9 (heptosyltransferase) K02517,K02843 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 369.0
TLS2_k127_2319326_0 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 603.0
TLS2_k127_2319326_1 Homocysteine s-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 401.0
TLS2_k127_2319326_2 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 384.0
TLS2_k127_2319326_3 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001115 260.0
TLS2_k127_2319326_4 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000001012 184.0
TLS2_k127_2319326_5 - - - - 0.0000000005807 66.0
TLS2_k127_2319326_6 Beta-lactamase - - - 0.0000005735 60.0
TLS2_k127_2319326_7 - - - - 0.00001206 47.0
TLS2_k127_2320148_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 1.798e-211 672.0
TLS2_k127_2320148_1 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 585.0
TLS2_k127_2320148_2 elongation factor Tu domain 2 protein K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 514.0
TLS2_k127_2320148_3 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 508.0
TLS2_k127_2320148_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K08641,K11206 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 411.0
TLS2_k127_2320148_5 Glutamate-cysteine ligase family 2(GCS2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 415.0
TLS2_k127_2320148_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009262 278.0
TLS2_k127_2320148_7 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000000000002049 152.0
TLS2_k127_2320148_8 DNA excision K02806 - - 0.0000000000000000008226 89.0
TLS2_k127_2320148_9 sulfuric ester hydrolase activity K03760,K06349,K19353 GO:0008150,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 2.7.8.43 0.000000000000008051 76.0
TLS2_k127_2325091_0 COG3119 Arylsulfatase A and related enzymes K01137 - 3.1.6.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 407.0
TLS2_k127_2325091_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 415.0
TLS2_k127_2325091_2 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000002322 237.0
TLS2_k127_2325091_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000003554 200.0
TLS2_k127_2348507_0 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001717 235.0
TLS2_k127_2348507_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000001054 121.0
TLS2_k127_2348507_2 Transposase DDE domain - - - 0.000000000000000000000002956 106.0
TLS2_k127_2348507_3 - - - - 0.000000000000000001503 94.0
TLS2_k127_2348507_4 - - - - 0.000000000000002226 80.0
TLS2_k127_2348507_5 Transposase DDE domain - - - 0.00000737 56.0
TLS2_k127_2348507_6 Belongs to the UPF0312 family - - - 0.0003809 48.0
TLS2_k127_2354524_0 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 6.355e-200 629.0
TLS2_k127_2354524_1 Belongs to the RimK family K05827 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 430.0
TLS2_k127_2354524_2 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 355.0
TLS2_k127_2356999_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1181.0
TLS2_k127_2356999_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 8.245e-275 852.0
TLS2_k127_2356999_10 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 338.0
TLS2_k127_2356999_11 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 364.0
TLS2_k127_2356999_12 PFAM Metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 317.0
TLS2_k127_2356999_13 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008493 280.0
TLS2_k127_2356999_14 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000367 257.0
TLS2_k127_2356999_15 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002805 246.0
TLS2_k127_2356999_16 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000001229 239.0
TLS2_k127_2356999_17 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000001876 213.0
TLS2_k127_2356999_18 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000006243 203.0
TLS2_k127_2356999_19 - - - - 0.000000000000000000000000000000000000000000004053 175.0
TLS2_k127_2356999_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 557.0
TLS2_k127_2356999_20 spore germination K00442,K03605,K04656,K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.000000000000000000000000000009202 124.0
TLS2_k127_2356999_21 EamA-like transporter family - - - 0.000000000000000000000000000226 127.0
TLS2_k127_2356999_22 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000004086 109.0
TLS2_k127_2356999_23 L-fucose isomerase and related - - - 0.00000000000000000002095 105.0
TLS2_k127_2356999_24 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000009381 92.0
TLS2_k127_2356999_25 Protein of unknown function, DUF488 - - - 0.00000000002976 66.0
TLS2_k127_2356999_27 - - - - 0.0000000987 60.0
TLS2_k127_2356999_28 Pilus assembly protein PilX - - - 0.000002465 49.0
TLS2_k127_2356999_3 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 512.0
TLS2_k127_2356999_4 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 494.0
TLS2_k127_2356999_5 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 515.0
TLS2_k127_2356999_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 480.0
TLS2_k127_2356999_7 Involved in the tonB-independent uptake of proteins - GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019586,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046397,GO:0071704,GO:0072329,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 474.0
TLS2_k127_2356999_8 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 421.0
TLS2_k127_2356999_9 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 361.0
TLS2_k127_2358394_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 545.0
TLS2_k127_2358394_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 298.0
TLS2_k127_2358394_2 Na channel or K07150 - - 0.00000000000000000000000005149 114.0
TLS2_k127_2359920_0 Domain of unknown function (DUF5107) - - - 1.909e-237 774.0
TLS2_k127_2359920_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001686 268.0
TLS2_k127_2359920_2 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006302 262.0
TLS2_k127_2359920_3 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000001383 217.0
TLS2_k127_2359920_4 - - - - 0.000000000000000000000000000004547 125.0
TLS2_k127_2359920_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000002801 123.0
TLS2_k127_2359920_6 Planctomycete cytochrome C - - - 0.0000000000000000000000000005329 132.0
TLS2_k127_2373990_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1112.0
TLS2_k127_2373990_1 Pyruvate:ferredoxin oxidoreductase core domain II K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 1.298e-232 726.0
TLS2_k127_2373990_2 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 403.0
TLS2_k127_2373990_3 synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 384.0
TLS2_k127_2373990_4 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 341.0
TLS2_k127_2373990_5 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000001213 249.0
TLS2_k127_2373990_6 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000001801 184.0
TLS2_k127_2388812_0 Putative esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000006443 215.0
TLS2_k127_2388812_1 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000001102 182.0
TLS2_k127_2388812_2 dioxygenase activity - - - 0.00003569 48.0
TLS2_k127_2396040_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 412.0
TLS2_k127_2396040_1 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 369.0
TLS2_k127_2396040_2 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000005907 252.0
TLS2_k127_2396040_3 PFAM Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000002229 198.0
TLS2_k127_2396040_4 elongation factor Tu domain 2 protein K06207 - - 0.000000000000000000000000000000000000000000000000004068 182.0
TLS2_k127_2396040_5 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000003788 172.0
TLS2_k127_2396040_7 Sulfotransferase family - - - 0.0000000000000000000000000001829 123.0
TLS2_k127_2396040_8 MacB-like periplasmic core domain - - - 0.0001589 49.0
TLS2_k127_2396040_9 Alstrom syndrome protein 1 K16741 GO:0000003,GO:0000086,GO:0000278,GO:0000922,GO:0001654,GO:0001678,GO:0001736,GO:0001738,GO:0001754,GO:0002009,GO:0003006,GO:0003008,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005814,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0005929,GO:0006629,GO:0006810,GO:0006996,GO:0007049,GO:0007154,GO:0007164,GO:0007165,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007292,GO:0007346,GO:0007399,GO:0007423,GO:0007600,GO:0007605,GO:0008092,GO:0008150,GO:0008152,GO:0008283,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010389,GO:0010564,GO:0010941,GO:0015630,GO:0016043,GO:0016192,GO:0016197,GO:0019722,GO:0019725,GO:0019932,GO:0019953,GO:0022008,GO:0022402,GO:0022406,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030030,GO:0030031,GO:0030154,GO:0030182,GO:0030728,GO:0031175,GO:0032231,GO:0032501,GO:0032502,GO:0032504,GO:0032956,GO:0032970,GO:0033043,GO:0033500,GO:0035556,GO:0036064,GO:0040008,GO:0040014,GO:0040015,GO:0042461,GO:0042462,GO:0042490,GO:0042592,GO:0042593,GO:0042632,GO:0042805,GO:0042981,GO:0042995,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043583,GO:0044085,GO:0044087,GO:0044238,GO:0044422,GO:0044424,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044450,GO:0044463,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0045444,GO:0045595,GO:0045598,GO:0045926,GO:0046530,GO:0046548,GO:0046907,GO:0048232,GO:0048468,GO:0048513,GO:0048515,GO:0048519,GO:0048523,GO:0048592,GO:0048609,GO:0048638,GO:0048640,GO:0048666,GO:0048699,GO:0048729,GO:0048731,GO:0048839,GO:0048856,GO:0048869,GO:0048878,GO:0050673,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050896,GO:0050954,GO:0051093,GO:0051128,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051393,GO:0051492,GO:0051493,GO:0051640,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0051726,GO:0055082,GO:0055088,GO:0055092,GO:0060113,GO:0060119,GO:0060122,GO:0060271,GO:0060429,GO:0060548,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071840,GO:0090596,GO:0097711,GO:0110020,GO:0110053,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0140056,GO:1901987,GO:1901990,GO:1902749,GO:1902903,GO:1903047 - 0.0005154 48.0
TLS2_k127_2397423_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 491.0
TLS2_k127_2397423_1 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 460.0
TLS2_k127_2397423_2 electron transfer activity K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 421.0
TLS2_k127_2397423_3 Domain of unknown function (DUF5009) - - - 0.000000000000000000000000000000000000000000000000000000000000000155 240.0
TLS2_k127_2397423_4 PFAM Bacterial Ig-like domain (group 2) - - - 0.000000000000000000000000000000000000000002027 166.0
TLS2_k127_2397423_5 lipolytic protein G-D-S-L family - - - 0.0000000000002526 83.0
TLS2_k127_2397423_6 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000001123 62.0
TLS2_k127_240931_0 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000001575 220.0
TLS2_k127_240931_1 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000003373 170.0
TLS2_k127_243206_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 425.0
TLS2_k127_243206_1 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000009414 132.0
TLS2_k127_243206_2 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000001071 81.0
TLS2_k127_243206_3 Protein of unknown function (DUF1559) - - - 0.00000000000308 77.0
TLS2_k127_243206_4 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.000000000006326 76.0
TLS2_k127_2464432_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 454.0
TLS2_k127_2464432_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 403.0
TLS2_k127_2464432_10 DNA / pantothenate metabolism flavoprotein K21977 - 6.3.2.5 0.000000000000000000000000000004397 131.0
TLS2_k127_2464432_11 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000003754 123.0
TLS2_k127_2464432_12 Dodecin K09165 - - 0.00000000000000000000000001106 109.0
TLS2_k127_2464432_13 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000001147 101.0
TLS2_k127_2464432_14 beta-galactosidase activity - - - 0.000000000000000000006966 106.0
TLS2_k127_2464432_15 Zinc ribbon domain - - - 0.000000000000000009174 87.0
TLS2_k127_2464432_16 Belongs to the UPF0109 family K06960 - - 0.00000000000000007291 82.0
TLS2_k127_2464432_2 aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 316.0
TLS2_k127_2464432_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 299.0
TLS2_k127_2464432_4 Pfam:Arch_ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001015 265.0
TLS2_k127_2464432_5 lipopolysaccharide 3-alpha-galactosyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001918 258.0
TLS2_k127_2464432_6 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000005988 261.0
TLS2_k127_2464432_7 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000000003025 203.0
TLS2_k127_2464432_8 Belongs to the P(II) protein family - - - 0.0000000000000000000000000000000000000000000000000001438 187.0
TLS2_k127_2464432_9 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000001014 162.0
TLS2_k127_2474842_0 Domain of unknown function (DUF5110) K01187,K18820 GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758,GO:0033825,GO:0046527 2.4.1.161,3.2.1.20 0.0 1062.0
TLS2_k127_2474842_1 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000001878 178.0
TLS2_k127_2474842_2 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000004323 162.0
TLS2_k127_2474842_3 reverse transcriptase K00986 - 2.7.7.49 0.000000000000000004149 85.0
TLS2_k127_2477707_0 PHP domain protein K07053 - 3.1.3.97 6.597e-318 990.0
TLS2_k127_2477707_1 56kDa selenium binding protein (SBP56) K17285 - - 5.692e-217 683.0
TLS2_k127_2477707_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 583.0
TLS2_k127_2477707_3 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 471.0
TLS2_k127_2477707_4 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 429.0
TLS2_k127_2477707_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 398.0
TLS2_k127_2477707_6 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000331 257.0
TLS2_k127_2477707_7 Methane oxygenase PmoA - - - 0.00000000000009344 72.0
TLS2_k127_249712_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 2.686e-196 620.0
TLS2_k127_249712_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 429.0
TLS2_k127_249712_2 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000002079 203.0
TLS2_k127_2499894_0 Putative exonuclease SbcCD, C subunit - - - 8.867e-316 1015.0
TLS2_k127_2499894_1 DEAD DEAH box helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 511.0
TLS2_k127_2499894_10 Crp Fnr family K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009808 258.0
TLS2_k127_2499894_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000001181 184.0
TLS2_k127_2499894_13 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000004754 175.0
TLS2_k127_2499894_14 PFAM Arginine-tRNA-protein transferase, C terminus K21420 - 2.3.2.29 0.0000000000000000000000000005533 124.0
TLS2_k127_2499894_2 Protein of unknown function (DUF2397) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 496.0
TLS2_k127_2499894_3 phosphoribosylamine-glycine ligase activity K01945,K01955 - 6.3.4.13,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 488.0
TLS2_k127_2499894_4 Protein of unknown function (DUF2398) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 399.0
TLS2_k127_2499894_5 Protein of unknown function C-terminus (DUF2399) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 386.0
TLS2_k127_2499894_6 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 363.0
TLS2_k127_2499894_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 348.0
TLS2_k127_2499894_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 302.0
TLS2_k127_2499894_9 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 282.0
TLS2_k127_2504627_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 3.713e-277 861.0
TLS2_k127_2504627_1 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000000000000000006299 169.0
TLS2_k127_2504627_2 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000931 134.0
TLS2_k127_2504627_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000004827 82.0
TLS2_k127_2527210_0 hydroperoxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 323.0
TLS2_k127_2527210_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 306.0
TLS2_k127_25273_0 glycoside hydrolase family 2 sugar binding - - - 2.469e-298 946.0
TLS2_k127_25273_1 Inosine-uridine preferring nucleoside hydrolase - - - 0.0000000000000000000000000000000000006268 149.0
TLS2_k127_2529974_0 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 395.0
TLS2_k127_2529974_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 381.0
TLS2_k127_2529974_2 Lrp/AsnC ligand binding domain - - - 0.00001275 47.0
TLS2_k127_253433_0 DEAD DEAH box helicase domain protein - - - 3.482e-228 734.0
TLS2_k127_253433_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 478.0
TLS2_k127_253433_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 449.0
TLS2_k127_253433_3 Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 408.0
TLS2_k127_253433_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007873 276.0
TLS2_k127_253433_5 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000001495 180.0
TLS2_k127_253433_6 - - - - 0.00000000000000000000000000000000000000002952 156.0
TLS2_k127_253433_7 metallophosphoesterase - - - 0.00000000000000000000000000000000001468 149.0
TLS2_k127_2537070_0 - K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 469.0
TLS2_k127_2537070_1 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 360.0
TLS2_k127_2537070_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000007151 221.0
TLS2_k127_2537070_3 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000008952 109.0
TLS2_k127_2537070_4 ROK family - - - 0.00006038 51.0
TLS2_k127_2544005_0 TIGRFAM sulfate thiosulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 494.0
TLS2_k127_2544005_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 477.0
TLS2_k127_2544005_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 359.0
TLS2_k127_2544005_3 Cellobiose phosphorylase K00702,K13688,K18675 - 2.4.1.20,2.4.1.280 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000336 272.0
TLS2_k127_2544005_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000003495 147.0
TLS2_k127_2544005_5 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000004632 121.0
TLS2_k127_2544005_6 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.0000000002332 67.0
TLS2_k127_2544005_7 - - - - 0.000000001009 71.0
TLS2_k127_2561432_0 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 485.0
TLS2_k127_2561432_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 348.0
TLS2_k127_2561432_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 357.0
TLS2_k127_2561432_3 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001547 270.0
TLS2_k127_2561432_4 Pectate lyase superfamily protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006983 226.0
TLS2_k127_2561432_5 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000002325 125.0
TLS2_k127_2570560_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.484e-247 778.0
TLS2_k127_2570560_1 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 454.0
TLS2_k127_2570560_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 325.0
TLS2_k127_2570560_3 TIGRFAM 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000001178 222.0
TLS2_k127_2570560_4 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000008754 211.0
TLS2_k127_2570560_5 - - - - 0.000000000000000000000004156 103.0
TLS2_k127_2570560_6 general secretion pathway protein K02456,K02650,K02679 - - 0.00000000000006342 82.0
TLS2_k127_2570560_7 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K11444 - 2.7.7.65 0.00000837 55.0
TLS2_k127_2603735_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 2.994e-235 733.0
TLS2_k127_2603735_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 531.0
TLS2_k127_2603735_2 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 395.0
TLS2_k127_2603735_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 386.0
TLS2_k127_2603735_4 Bacterial type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 372.0
TLS2_k127_2603735_5 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000001474 232.0
TLS2_k127_2603735_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000005165 218.0
TLS2_k127_2603735_7 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000001927 186.0
TLS2_k127_2603735_8 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000007695 151.0
TLS2_k127_2604485_0 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001814 273.0
TLS2_k127_2604485_1 ABC transporter K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000001739 258.0
TLS2_k127_2604485_2 COG1668 ABC-type Na efflux pump, permease component K01992,K09696 - - 0.000000000000000000000000000000000000000000001118 188.0
TLS2_k127_2604485_3 ABC-2 family transporter protein K09696 - - 0.000000012 60.0
TLS2_k127_2614133_0 Cytochrome c - - - 1.965e-194 616.0
TLS2_k127_2614133_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000001367 210.0
TLS2_k127_2614133_2 Peptidase, S41 - - - 0.00000000000000000000000000000000000000000000000000000000001081 225.0
TLS2_k127_2614133_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000525 200.0
TLS2_k127_2614133_4 - - - - 0.00000000000000000000000000000000000000000000000000001425 198.0
TLS2_k127_2614133_5 - - - - 0.0000000000000000000000000000000001792 134.0
TLS2_k127_2614133_6 Alpha beta hydrolase K00433 - 1.11.1.10 0.000000001843 59.0
TLS2_k127_2614133_7 Belongs to the UPF0337 (CsbD) family - - - 0.00000002463 58.0
TLS2_k127_2614133_8 DNA-templated transcription, initiation - - - 0.00000003828 60.0
TLS2_k127_2614133_9 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0006373 44.0
TLS2_k127_2629987_0 - - - - 3.497e-273 915.0
TLS2_k127_2629987_1 Bacterial alpha-L-rhamnosidase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 478.0
TLS2_k127_2629987_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 360.0
TLS2_k127_2629987_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000005767 235.0
TLS2_k127_2629987_4 - - - - 0.0000000000000000000000000000000000000000000000000001928 207.0
TLS2_k127_2629987_5 filamentous hemagglutinin family N-terminal domain - - - 0.000000000000000000000000000000006609 151.0
TLS2_k127_2629987_6 Pectate lyase K01179,K01406,K21449 - 3.2.1.4,3.4.24.40 0.000000000000004069 86.0
TLS2_k127_2633234_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.291e-229 730.0
TLS2_k127_2633234_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.211e-215 676.0
TLS2_k127_2633234_2 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 519.0
TLS2_k127_2633234_3 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001284 278.0
TLS2_k127_2633234_4 R3H domain - - - 0.0000000000000000000000057 108.0
TLS2_k127_2633234_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000002999 59.0
TLS2_k127_2633234_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000004596 56.0
TLS2_k127_2633234_7 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000002467 50.0
TLS2_k127_2698423_0 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 321.0
TLS2_k127_2698423_1 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003295 258.0
TLS2_k127_2698423_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000002337 240.0
TLS2_k127_2698423_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000001137 210.0
TLS2_k127_2716889_0 Belongs to the glycosyl hydrolase 13 family K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000008263 249.0
TLS2_k127_2723830_0 ASPIC UnbV domain protein - - - 3.812e-299 967.0
TLS2_k127_2723830_1 ASPIC UnbV domain protein - - - 7.811e-278 898.0
TLS2_k127_2723830_2 Beta-L-arabinofuranosidase, GH127 - - - 4.024e-238 754.0
TLS2_k127_2723830_3 HELICc2 K07464,K10844 - 3.1.12.1,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 377.0
TLS2_k127_2723830_4 quinone binding K01829,K03673,K03805,K03981,K12228 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0055114,GO:0140096 5.3.4.1 0.000000000000000000000000000000000000000000000005287 189.0
TLS2_k127_2723852_0 Rhodanese Homology Domain K00529 - 1.18.1.3 2.216e-210 668.0
TLS2_k127_2723852_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 492.0
TLS2_k127_2723852_2 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 324.0
TLS2_k127_2723852_3 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 306.0
TLS2_k127_2723852_4 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000000000005236 188.0
TLS2_k127_2723852_5 Thioredoxin K03671 - - 0.0000000000000000000000000000000003531 138.0
TLS2_k127_2723852_6 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000002542 105.0
TLS2_k127_2723852_7 cellulose binding - - - 0.00000000401 62.0
TLS2_k127_2738058_1 Transposase IS4 family - - - 0.00000000000000000000000000000000000000000003731 161.0
TLS2_k127_2738058_2 PFAM Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000005795 113.0
TLS2_k127_2738058_3 serine-type peptidase activity K06978,K21105 - 3.1.1.102 0.000000000001861 80.0
TLS2_k127_2738058_4 transposase activity - - - 0.000000002863 58.0
TLS2_k127_275033_0 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000001846 178.0
TLS2_k127_275033_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000001831 149.0
TLS2_k127_275033_2 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000001173 113.0
TLS2_k127_275033_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000009296 70.0
TLS2_k127_275033_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000001328 64.0
TLS2_k127_275790_0 Molybdopterin oxidoreductase - - - 0.0 1054.0
TLS2_k127_275790_1 Protein of unknown function (DUF1501) - - - 2.038e-226 711.0
TLS2_k127_275790_2 peptidyl-tyrosine sulfation - - - 8.62e-224 715.0
TLS2_k127_275790_3 Planctomycete cytochrome C - - - 9.282e-198 638.0
TLS2_k127_275790_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 561.0
TLS2_k127_275790_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 439.0
TLS2_k127_275790_6 Participates in the control of copper homeostasis K06201 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001066 278.0
TLS2_k127_275790_7 NnrS protein - - - 0.000000000000000000000000000000000000000000000000000000000000001582 233.0
TLS2_k127_275790_8 - - - - 0.000000000000000000000000000000000002245 151.0
TLS2_k127_275790_9 Nitrate reductase delta subunit - - - 0.00000000000000000003749 104.0
TLS2_k127_2778456_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 381.0
TLS2_k127_2778456_1 Sigma-70, region 4 - - - 0.00000000000000000000000000000000257 137.0
TLS2_k127_278000_0 COG3119 Arylsulfatase A and related enzymes K01138 - - 1.519e-207 655.0
TLS2_k127_278000_1 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 451.0
TLS2_k127_278000_2 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 384.0
TLS2_k127_278000_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 349.0
TLS2_k127_278000_4 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000001063 201.0
TLS2_k127_278000_5 Predicted membrane protein (DUF2339) - - - 0.00000000002315 75.0
TLS2_k127_278000_6 pathogenesis - - - 0.000000001568 72.0
TLS2_k127_278000_7 Involved in the tonB-independent uptake of proteins - - - 0.0000001287 66.0
TLS2_k127_278000_8 Protein of unknown function (DUF1559) - - - 0.0000002116 62.0
TLS2_k127_2806070_0 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 439.0
TLS2_k127_2806070_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000006128 217.0
TLS2_k127_2806070_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000005447 184.0
TLS2_k127_2806070_3 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000009065 185.0
TLS2_k127_2806070_4 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000001087 85.0
TLS2_k127_2806070_5 Trehalose utilisation K09992 - - 0.000008618 52.0
TLS2_k127_2806787_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 0.0 1343.0
TLS2_k127_2806787_1 AAA-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 477.0
TLS2_k127_2806787_10 Pilus assembly protein PilX - - - 0.0000000000000000000000000000000004914 147.0
TLS2_k127_2806787_11 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog)) K04762,K06179,K06180 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.23,5.4.99.24 0.000000000000000000000000000000159 132.0
TLS2_k127_2806787_12 LacY proton/sugar symporter - - - 0.000000000000000000000000000002014 135.0
TLS2_k127_2806787_13 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000001763 131.0
TLS2_k127_2806787_14 HEAT repeat-containing protein - - - 0.000000000000000000000006896 117.0
TLS2_k127_2806787_15 - - - - 0.0000000000000000000000952 114.0
TLS2_k127_2806787_16 Protein of unknown function (DUF1318) K09978 - - 0.00000000000000004277 86.0
TLS2_k127_2806787_18 - - - - 0.0000000000002651 72.0
TLS2_k127_2806787_19 SNAP receptor activity - - - 0.000002203 59.0
TLS2_k127_2806787_2 Belongs to the DapA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 445.0
TLS2_k127_2806787_20 - - - - 0.00001274 51.0
TLS2_k127_2806787_21 Prokaryotic N-terminal methylation motif - - - 0.0003084 50.0
TLS2_k127_2806787_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 386.0
TLS2_k127_2806787_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000128 294.0
TLS2_k127_2806787_5 PFAM Rhomboid family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000075 252.0
TLS2_k127_2806787_6 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000003776 218.0
TLS2_k127_2806787_7 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000004497 224.0
TLS2_k127_2806787_8 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000009979 154.0
TLS2_k127_2806787_9 Histidine kinase K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000009154 163.0
TLS2_k127_281129_0 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 599.0
TLS2_k127_2815464_0 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000000008672 114.0
TLS2_k127_2815464_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000001887 108.0
TLS2_k127_2815464_2 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.0000001767 62.0
TLS2_k127_2815464_3 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.000005534 57.0
TLS2_k127_2815464_4 - - - - 0.00002158 55.0
TLS2_k127_2817189_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 576.0
TLS2_k127_2817189_1 Associated with various cellular activities K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 449.0
TLS2_k127_2817189_2 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000007639 162.0
TLS2_k127_2817189_4 DUF167 K09131 - - 0.00000000000000000000001512 103.0
TLS2_k127_2831071_0 Phosphopantetheine attachment site - - - 0.0 1723.0
TLS2_k127_2831071_1 Phosphopantetheine attachment site - - - 2.669e-217 685.0
TLS2_k127_2831071_2 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 575.0
TLS2_k127_2831071_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 529.0
TLS2_k127_2831071_4 ornithine cyclodeaminase activity K01750,K20500 - 4.3.1.12,4.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 475.0
TLS2_k127_2831071_5 HupE / UreJ protein - - - 0.00000000000000000000000268 103.0
TLS2_k127_2841318_0 AMP-binding enzyme C-terminal domain - - - 8.789e-200 639.0
TLS2_k127_2841318_1 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 596.0
TLS2_k127_2841318_10 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000000000000000000000000000000000000000000002315 182.0
TLS2_k127_2841318_11 acyl carrier protein - - - 0.0000000000000000000000008058 106.0
TLS2_k127_2841318_12 electron transfer flavoprotein, alpha subunit K03522 - - 0.0006171 45.0
TLS2_k127_2841318_2 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 509.0
TLS2_k127_2841318_3 negative regulation of protein lipidation K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 531.0
TLS2_k127_2841318_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 409.0
TLS2_k127_2841318_5 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 381.0
TLS2_k127_2841318_6 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 363.0
TLS2_k127_2841318_7 Electron transfer flavoprotein, beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006325 259.0
TLS2_k127_2841318_8 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K00773,K07319,K11782,K15461 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000003896 250.0
TLS2_k127_2841318_9 Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000001706 214.0
TLS2_k127_2844150_0 Planctomycete cytochrome C - - - 3.177e-280 897.0
TLS2_k127_2844150_1 sulfuric ester hydrolase activity K01992 - - 8.967e-228 713.0
TLS2_k127_2844150_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 534.0
TLS2_k127_2844150_3 Transfers electrons from cytochrome c551 to cytochrome oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 351.0
TLS2_k127_2844150_4 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003824 278.0
TLS2_k127_2849776_0 Tricorn protease homolog - - - 0.0 1255.0
TLS2_k127_2849776_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 544.0
TLS2_k127_2849776_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 447.0
TLS2_k127_2849776_3 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 434.0
TLS2_k127_2849776_4 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 409.0
TLS2_k127_2849776_5 phosphorelay sensor kinase activity K13598,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 377.0
TLS2_k127_2849776_6 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000009625 113.0
TLS2_k127_28860_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.559e-243 760.0
TLS2_k127_28860_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.191e-236 736.0
TLS2_k127_28860_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000001102 106.0
TLS2_k127_28860_11 ATP synthase subunit C K02110 - - 0.000000000000000000000589 96.0
TLS2_k127_28860_12 - - - - 0.000000000000000000002183 106.0
TLS2_k127_28860_13 Large extracellular alpha-helical protein K06894 - - 0.00000000000000436 79.0
TLS2_k127_28860_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 1.199e-223 711.0
TLS2_k127_28860_3 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 603.0
TLS2_k127_28860_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008928 533.0
TLS2_k127_28860_5 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 413.0
TLS2_k127_28860_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 382.0
TLS2_k127_28860_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 298.0
TLS2_k127_28860_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000001547 166.0
TLS2_k127_28860_9 ATP synthase delta (OSCP) subunit K02113 - - 0.0000000000000000000000044 106.0
TLS2_k127_2905585_0 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 555.0
TLS2_k127_2905585_1 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 549.0
TLS2_k127_2905585_10 Response regulator, receiver - - - 0.00000000000000000000000000001665 123.0
TLS2_k127_2905585_11 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.00000000000000000000000008854 118.0
TLS2_k127_2905585_12 - - - - 0.000000000000000000717 95.0
TLS2_k127_2905585_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 469.0
TLS2_k127_2905585_3 PFAM type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 444.0
TLS2_k127_2905585_4 ATPase-coupled phosphate ion transmembrane transporter activity K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 387.0
TLS2_k127_2905585_5 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 386.0
TLS2_k127_2905585_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001148 272.0
TLS2_k127_2905585_7 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000543 243.0
TLS2_k127_2905585_8 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000001242 231.0
TLS2_k127_2905585_9 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000001603 171.0
TLS2_k127_2911104_0 ParB-like nuclease domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 523.0
TLS2_k127_2911104_1 domain protein K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 411.0
TLS2_k127_2911104_2 cellulose binding - - - 0.00000000000000000000000000000000000001498 166.0
TLS2_k127_2911104_3 Protein of unknown function (DUF3489) - - - 0.000000000001044 76.0
TLS2_k127_2911104_5 Belongs to the 'phage' integrase family - - - 0.00000006263 54.0
TLS2_k127_2918304_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 7.896e-230 730.0
TLS2_k127_2918304_1 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 544.0
TLS2_k127_2918304_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 411.0
TLS2_k127_2918304_3 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000000000000000000000000241 225.0
TLS2_k127_2918304_4 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000014 202.0
TLS2_k127_2918304_6 - - - - 0.0002154 52.0
TLS2_k127_293448_0 - - - - 0.00000000000000000000163 102.0
TLS2_k127_293448_1 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.0000000000000001726 82.0
TLS2_k127_293448_2 - - - - 0.00000000000004825 76.0
TLS2_k127_293448_3 - - - - 0.000000000157 67.0
TLS2_k127_2935020_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005942 307.0
TLS2_k127_2935020_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000005412 77.0
TLS2_k127_2935020_3 DDE superfamily endonuclease - - - 0.00000000003298 64.0
TLS2_k127_2935020_4 Resolvase, N terminal domain - - - 0.00000005767 57.0
TLS2_k127_2941395_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 426.0
TLS2_k127_2941395_1 Cupin 2, conserved barrel domain protein K19547 - 5.3.3.19 0.0000000000000000000000000000000000000000000003777 169.0
TLS2_k127_2941395_2 Oxygen tolerance - - - 0.000000000000000000000278 107.0
TLS2_k127_2941395_3 Hep Hag repeat protein K21449 - - 0.0000000000000000001038 102.0
TLS2_k127_2941395_4 tetratricopeptide repeat - - - 0.0000000000000000001723 101.0
TLS2_k127_2941395_5 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.0000000000002449 79.0
TLS2_k127_2968725_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1033.0
TLS2_k127_2968725_1 hydrolase activity, acting on ester bonds K07051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 466.0
TLS2_k127_2968725_2 Protein of unknown function (DUF3347) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 479.0
TLS2_k127_2968725_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 354.0
TLS2_k127_2968725_4 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000004226 234.0
TLS2_k127_2968725_5 - - - - 0.0000000000000000000000000001187 119.0
TLS2_k127_2968725_6 - - - - 0.000000000000003255 86.0
TLS2_k127_2968725_7 efflux transmembrane transporter activity - - - 0.0003446 53.0
TLS2_k127_3000922_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 603.0
TLS2_k127_3000922_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 443.0
TLS2_k127_3000922_2 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 398.0
TLS2_k127_3000922_3 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 392.0
TLS2_k127_3000922_4 - - - - 0.0000000000002577 76.0
TLS2_k127_3000922_5 general secretion pathway protein K02456,K02650,K02679 - - 0.00000000000975 75.0
TLS2_k127_3000922_6 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000007142 68.0
TLS2_k127_3000922_7 serine threonine protein kinase - - - 0.0000005304 61.0
TLS2_k127_3010188_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 299.0
TLS2_k127_3010188_1 PQQ-like domain - - - 0.00000000000000000000005202 116.0
TLS2_k127_3010188_2 beta-propeller repeat - - - 0.0000000000000000000003579 96.0
TLS2_k127_3010188_3 - - - - 0.000000000000001515 78.0
TLS2_k127_30264_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 318.0
TLS2_k127_30264_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 319.0
TLS2_k127_30264_2 phosphate ion binding K02040 - - 0.00001017 57.0
TLS2_k127_3030019_0 COG0339 Zn-dependent oligopeptidases K01284 - 3.4.15.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 325.0
TLS2_k127_3030019_1 - - - - 0.0000000000000000000000000000000000000000000000000001008 205.0
TLS2_k127_3030019_2 - - - - 0.00000000000000000000000000000000000006856 164.0
TLS2_k127_3030019_3 Penicillinase repressor - - - 0.000000000000000000000000001709 117.0
TLS2_k127_3032303_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 413.0
TLS2_k127_3032303_1 Sulfatase - - - 0.00000000000000000000001799 103.0
TLS2_k127_3066165_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 1.079e-281 890.0
TLS2_k127_3066165_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 3.663e-213 687.0
TLS2_k127_3066165_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 1.932e-200 637.0
TLS2_k127_3066351_0 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000001234 184.0
TLS2_k127_3066351_1 Na channel or K07150 - - 0.000000000000000000000000000000001132 139.0
TLS2_k127_3067105_0 Gluconate K03299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 515.0
TLS2_k127_3067105_1 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 421.0
TLS2_k127_3067105_2 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000000000000000000000006408 228.0
TLS2_k127_3067105_3 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000000000001231 213.0
TLS2_k127_3071194_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 526.0
TLS2_k127_3071194_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 515.0
TLS2_k127_3071194_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 475.0
TLS2_k127_3071194_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 288.0
TLS2_k127_3071194_4 Cation transport protein K03498,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001248 291.0
TLS2_k127_3071194_5 TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000004107 168.0
TLS2_k127_3071194_6 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000001027 113.0
TLS2_k127_3072407_0 ATP-dependent helicase C-terminal K03579 - 3.6.4.13 8.261e-303 954.0
TLS2_k127_3072407_1 Spore coat protein CotH K07093 - - 4.53e-223 753.0
TLS2_k127_3072407_10 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000001328 189.0
TLS2_k127_3072407_11 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.000000000000000000000000000002118 142.0
TLS2_k127_3072407_12 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000001917 101.0
TLS2_k127_3072407_2 PFAM UvrD REP helicase K03656,K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 555.0
TLS2_k127_3072407_3 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 510.0
TLS2_k127_3072407_4 Belongs to the glycosyl hydrolase 43 family K22350 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 496.0
TLS2_k127_3072407_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 413.0
TLS2_k127_3072407_6 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 380.0
TLS2_k127_3072407_7 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001473 274.0
TLS2_k127_3072407_8 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000001139 224.0
TLS2_k127_3072407_9 HDOD domain K03088 - - 0.0000000000000000000000000000000000000000000000000000000001703 208.0
TLS2_k127_3075395_0 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000001969 135.0
TLS2_k127_3075395_1 Protein of unknown function, DUF488 - - - 0.0000000000000000000000004275 108.0
TLS2_k127_3075395_2 HEAT repeat - - - 0.0000009633 60.0
TLS2_k127_3109265_0 SERine Proteinase INhibitors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 436.0
TLS2_k127_3109265_1 UPF0365 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008179 424.0
TLS2_k127_3109265_2 Membrane-bound serine protease (ClpP class) K07403 - - 0.00000000000000000000001979 105.0
TLS2_k127_3109265_3 phosphorelay signal transduction system - - - 0.00000005752 61.0
TLS2_k127_3155122_0 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 434.0
TLS2_k127_3155122_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 375.0
TLS2_k127_3155122_2 4'-phosphopantetheinyl transferase superfamily - - - 0.0000000000000000000000000000000000000000005798 168.0
TLS2_k127_3155122_3 lipid kinase activity - - - 0.000000000000000000000000000000000565 137.0
TLS2_k127_3166881_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 9.141e-299 933.0
TLS2_k127_3166881_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.314e-241 756.0
TLS2_k127_3166881_10 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000001203 224.0
TLS2_k127_3166881_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000004204 201.0
TLS2_k127_3166881_12 DnaJ molecular chaperone homology domain K05516 - - 0.0000000000000000000000000000000000000000000000002417 182.0
TLS2_k127_3166881_13 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000355 189.0
TLS2_k127_3166881_14 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K07025 - - 0.000000000000000000000000000004619 129.0
TLS2_k127_3166881_15 Binds directly to 16S ribosomal RNA K02968 - - 0.00000002568 61.0
TLS2_k127_3166881_2 Trypsin-like serine protease K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 452.0
TLS2_k127_3166881_3 FMN-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 366.0
TLS2_k127_3166881_4 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 292.0
TLS2_k127_3166881_5 Oxidoreductase family, NAD-binding Rossmann fold K00118 - 1.1.99.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 297.0
TLS2_k127_3166881_6 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000605 304.0
TLS2_k127_3166881_7 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 285.0
TLS2_k127_3166881_8 TIGRFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000005394 252.0
TLS2_k127_3166881_9 - K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000001598 237.0
TLS2_k127_3175398_0 ABC transporter transmembrane region K06147 - - 1.78e-231 732.0
TLS2_k127_3175398_1 Phosphopantetheine attachment site - - - 0.0000000000000000000000000000000000000000000000000000000000359 216.0
TLS2_k127_3179503_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 7.002e-209 661.0
TLS2_k127_3179503_1 - - - - 0.0000000000000000000000000000000000000000000000000000000001916 209.0
TLS2_k127_3179503_2 transferase activity, transferring acyl groups other than amino-acyl groups K11941 - - 0.00000000000000000000000000000000000000000000000001211 196.0
TLS2_k127_3179503_3 chaperone-mediated protein folding - - - 0.00000001723 67.0
TLS2_k127_3192132_0 Protein conserved in bacteria K09955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 449.0
TLS2_k127_3192132_2 Cytochrome c - - - 0.000001943 49.0
TLS2_k127_3202087_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008519 279.0
TLS2_k127_3214893_0 PQQ-like domain - - - 0.0000000000000000000000000001047 130.0
TLS2_k127_3214893_1 Transposase DDE domain - - - 0.000000000000000000001097 100.0
TLS2_k127_3217183_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.452e-207 659.0
TLS2_k127_3217183_1 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 8.795e-207 653.0
TLS2_k127_3217183_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 436.0
TLS2_k127_3217183_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 429.0
TLS2_k127_3217183_4 growth of symbiont in host cell K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 316.0
TLS2_k127_3217183_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.4.2.9 0.000000000000000000000000000000000000000000000000000000001257 205.0
TLS2_k127_3217183_6 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000001591 171.0
TLS2_k127_3217183_7 - - - - 0.00000000000000000001267 93.0
TLS2_k127_3217183_9 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000001644 64.0
TLS2_k127_3265338_0 Transfers electrons from cytochrome c551 to cytochrome oxidase - - - 0.0 1266.0
TLS2_k127_3265338_1 PFAM DNA topoisomerase type IA zn finger domain protein - - - 0.000000000000000000000000008014 113.0
TLS2_k127_3265338_2 23S rRNA-intervening sequence protein - - - 0.0000000000006261 70.0
TLS2_k127_3295086_0 PFAM SAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 591.0
TLS2_k127_3295086_1 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 546.0
TLS2_k127_3295086_10 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000001314 222.0
TLS2_k127_3295086_11 - - - - 0.00000000000000000000000000000000000000000000000000002802 201.0
TLS2_k127_3295086_12 winged helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000009515 189.0
TLS2_k127_3295086_13 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000005537 81.0
TLS2_k127_3295086_14 Polysaccharide pyruvyl transferase - - - 0.0000000002885 72.0
TLS2_k127_3295086_2 PFAM FAD dependent oxidoreductase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 529.0
TLS2_k127_3295086_3 Putative zinc binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 520.0
TLS2_k127_3295086_4 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 495.0
TLS2_k127_3295086_5 Nucleotidyl transferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 423.0
TLS2_k127_3295086_6 Membrane protein involved in the export of O-antigen and teichoic acid K03328 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 351.0
TLS2_k127_3295086_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 332.0
TLS2_k127_3295086_8 dTDP-4-dehydrorhamnose 3,5-epimerase K00067,K01790 - 1.1.1.133,5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000001181 267.0
TLS2_k127_3295086_9 Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003456 265.0
TLS2_k127_329761_0 COG1233 Phytoene dehydrogenase and related - - - 3.107e-217 689.0
TLS2_k127_329761_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008786 415.0
TLS2_k127_329761_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 345.0
TLS2_k127_329761_3 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000004718 231.0
TLS2_k127_329761_4 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000945 183.0
TLS2_k127_329761_5 Rubrerythrin K22336 - 1.16.3.1 0.0000000000000000000000000000000000000000009191 162.0
TLS2_k127_329761_6 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000004836 156.0
TLS2_k127_329761_7 - - - - 0.000000004998 69.0
TLS2_k127_3315531_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 552.0
TLS2_k127_3315531_1 LppP/LprE lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 321.0
TLS2_k127_3315531_2 cellulose binding - - - 0.000000000000000000000000000000005698 136.0
TLS2_k127_3315531_3 YqcI/YcgG family - - - 0.00000000005582 63.0
TLS2_k127_333481_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 494.0
TLS2_k127_333481_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 447.0
TLS2_k127_333481_2 Oxidoreductase K13327 - 1.1.1.384 0.000000000000000000000000000000000000000000000000000004847 201.0
TLS2_k127_333481_4 Macrocin-O-methyltransferase (TylF) - - - 0.0000000000000000000000000000000000001705 153.0
TLS2_k127_3341136_0 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 475.0
TLS2_k127_3341136_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 406.0
TLS2_k127_3341136_2 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005189 284.0
TLS2_k127_3341136_3 - - - - 0.000000000000000003736 89.0
TLS2_k127_3358605_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 3.84e-217 683.0
TLS2_k127_3358605_1 Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 520.0
TLS2_k127_3358605_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000482 278.0
TLS2_k127_3358605_3 ApaG domain K06195 - - 0.00000000000000000000000000000000003538 138.0
TLS2_k127_3362375_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 370.0
TLS2_k127_3362375_1 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.000000000000000000000000000000000000000002856 158.0
TLS2_k127_3362375_2 Gram-negative-bacterium-type cell wall biogenesis - - - 0.000000000000000000000000000000000000003201 157.0
TLS2_k127_3362375_3 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000002888 142.0
TLS2_k127_3362375_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000008401 132.0
TLS2_k127_3362375_5 - - - - 0.00000000000000000000000027 122.0
TLS2_k127_3362375_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000002577 76.0
TLS2_k127_3362375_7 histidine kinase A domain protein - - - 0.0000000009158 64.0
TLS2_k127_3362375_9 Membrane-flanked domain - - - 0.0001 51.0
TLS2_k127_3373390_0 ASPIC and UnbV - - - 2.092e-209 668.0
TLS2_k127_3373390_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 590.0
TLS2_k127_3375340_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 516.0
TLS2_k127_3375340_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 462.0
TLS2_k127_3375340_2 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000001538 198.0
TLS2_k127_3375340_3 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000007187 157.0
TLS2_k127_3398830_0 Na H antiporter - - - 2.411e-209 670.0
TLS2_k127_3398830_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001352 237.0
TLS2_k127_3398830_2 Domain of unknown function (DUF892) - - - 0.00000000000000000000000000000000000000000000000000000000000000008431 233.0
TLS2_k127_3398830_3 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000000000000000000000000000000000000000000005031 203.0
TLS2_k127_3398830_4 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000000000000002384 181.0
TLS2_k127_3398830_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000003279 166.0
TLS2_k127_3398830_6 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000000000000000000002143 140.0
TLS2_k127_3398830_7 Protein of unknown function (DUF1559) K02456 - - 0.0000000000000003026 89.0
TLS2_k127_3398830_8 AntiSigma factor - - - 0.0000000000000009008 88.0
TLS2_k127_3398830_9 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000005194 86.0
TLS2_k127_3400193_0 Glycosyl hydrolases family 2 - - - 8.901e-273 869.0
TLS2_k127_3400193_1 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 488.0
TLS2_k127_3400193_10 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00003249 57.0
TLS2_k127_3400193_11 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00106 - 1.17.1.4,1.17.3.2 0.0008684 44.0
TLS2_k127_3400193_2 SGNH hydrolase-like domain, acetyltransferase AlgX K19295 - - 0.0000000000000000000000000000000000000000000000000000000001681 218.0
TLS2_k127_3400193_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000002724 181.0
TLS2_k127_3400193_4 PFAM sodium hydrogen exchanger K03316 - - 0.000000000000000000000000000000000001572 141.0
TLS2_k127_3400193_6 transcriptional regulator AraC family - - - 0.0000000000000000000296 102.0
TLS2_k127_3400193_7 general secretion pathway protein K02456 - - 0.0000000000000008316 87.0
TLS2_k127_3400193_8 - - - - 0.00000000000002739 81.0
TLS2_k127_3400193_9 Transcriptional regulatory protein, C terminal - - - 0.0000000005036 73.0
TLS2_k127_3406725_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 493.0
TLS2_k127_3406725_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005097 292.0
TLS2_k127_3406725_2 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000004359 185.0
TLS2_k127_3406725_3 Acetyl xylan esterase (AXE1) - - - 0.0000000000000000000000000000000000000000001482 166.0
TLS2_k127_3433877_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.098e-267 830.0
TLS2_k127_3433877_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 5.716e-257 808.0
TLS2_k127_3433877_10 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 375.0
TLS2_k127_3433877_11 Belongs to the complex I 20 kDa subunit family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 325.0
TLS2_k127_3433877_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 301.0
TLS2_k127_3433877_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001764 268.0
TLS2_k127_3433877_14 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.000000000000000000000000000000000000000000000000000001151 197.0
TLS2_k127_3433877_15 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000002156 188.0
TLS2_k127_3433877_16 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000000000000000000000000000000195 162.0
TLS2_k127_3433877_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000000005265 152.0
TLS2_k127_3433877_18 Outer membrane lipoprotein carrier protein LolA - - - 0.000000000000000000000000000000000003881 147.0
TLS2_k127_3433877_19 FabA-like domain - - - 0.00000000000000000000000000000000033 145.0
TLS2_k127_3433877_2 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K12142,K15830 GO:0003674,GO:0005488,GO:0016151,GO:0043167,GO:0043169,GO:0046872,GO:0046914 1.6.5.3 2.063e-255 799.0
TLS2_k127_3433877_20 spore germination K00442,K08315 - 3.4.23.51 0.00000000000000000000001301 111.0
TLS2_k127_3433877_21 TIGRFAM F1 F0 ATPase, Methanosarcina type, subunit 2 - - - 0.0000000000000000000000293 103.0
TLS2_k127_3433877_22 Bacterial lipid A biosynthesis acyltransferase - - - 0.0000000000000000189 87.0
TLS2_k127_3433877_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.378e-253 794.0
TLS2_k127_3433877_4 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 574.0
TLS2_k127_3433877_5 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 559.0
TLS2_k127_3433877_6 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 501.0
TLS2_k127_3433877_7 ATP synthase K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 425.0
TLS2_k127_3433877_8 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 390.0
TLS2_k127_3433877_9 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 387.0
TLS2_k127_3443690_0 COG0668 Small-conductance mechanosensitive channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 520.0
TLS2_k127_3443690_1 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 528.0
TLS2_k127_3443690_2 Manganese containing catalase K07217 - - 0.000000000000000000002109 96.0
TLS2_k127_3443690_3 serves to protect cells from the toxic effects of hydrogen peroxide K03781 GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006970,GO:0006972,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0042221,GO:0042737,GO:0042743,GO:0042744,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1990748 1.11.1.6 0.0000000004574 61.0
TLS2_k127_3448997_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 416.0
TLS2_k127_3448997_1 DNA-directed DNA polymerase K02337,K14162 - 2.7.7.7 0.00000000000000002114 91.0
TLS2_k127_3480249_0 Acetyl xylan esterase (AXE1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 555.0
TLS2_k127_3480249_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000004921 136.0
TLS2_k127_3525527_0 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 489.0
TLS2_k127_3525527_1 Belongs to the ABC transporter superfamily K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 387.0
TLS2_k127_3525527_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 334.0
TLS2_k127_3525527_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 332.0
TLS2_k127_3525527_4 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000001656 190.0
TLS2_k127_3525527_5 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000001283 177.0
TLS2_k127_3525527_6 - - - - 0.0000000000000000000001207 108.0
TLS2_k127_3531744_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 528.0
TLS2_k127_3531744_1 isocitrate dehydrogenase activity K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 357.0
TLS2_k127_3566991_0 Pyrrolo-quinoline quinone K00117 - 1.1.5.2 6.052e-230 733.0
TLS2_k127_3566991_1 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 605.0
TLS2_k127_3566991_10 Endonuclease/Exonuclease/phosphatase family K12351 GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005773,GO:0005783,GO:0005886,GO:0006629,GO:0006643,GO:0006665,GO:0006672,GO:0006807,GO:0006950,GO:0006970,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009628,GO:0009651,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0019867,GO:0030148,GO:0030149,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032592,GO:0032995,GO:0034641,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0044087,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0046466,GO:0046467,GO:0046513,GO:0046519,GO:0046521,GO:0050789,GO:0050794,GO:0050896,GO:0052712,GO:0052713,GO:0052714,GO:0065007,GO:0071704,GO:0071944,GO:0097164,GO:0098573,GO:0098588,GO:0098805,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1903338 3.1.4.12 0.00000008112 64.0
TLS2_k127_3566991_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 562.0
TLS2_k127_3566991_3 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 421.0
TLS2_k127_3566991_4 PFAM Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 371.0
TLS2_k127_3566991_5 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 360.0
TLS2_k127_3566991_6 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 336.0
TLS2_k127_3566991_7 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002325 282.0
TLS2_k127_3566991_8 - - - - 0.00000000000000000000000005958 108.0
TLS2_k127_3566991_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000002171 106.0
TLS2_k127_357840_0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 417.0
TLS2_k127_357840_1 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001624 283.0
TLS2_k127_357840_2 Domain of Unknown Function (DUF1080) - - - 0.0000000000005222 69.0
TLS2_k127_3608484_0 protein kinase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 587.0
TLS2_k127_3608484_1 Glycosyl hydrolases family 43 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005377 266.0
TLS2_k127_3608484_2 PIN domain - - - 0.000000000000000000000000000000000000000000001264 169.0
TLS2_k127_3608484_3 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00000000001551 68.0
TLS2_k127_3630618_0 NAD(P)H-binding K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 421.0
TLS2_k127_3630618_1 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 291.0
TLS2_k127_3630618_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000002192 167.0
TLS2_k127_3669026_0 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 510.0
TLS2_k127_3669026_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 429.0
TLS2_k127_3669026_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 411.0
TLS2_k127_3669026_3 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001225 285.0
TLS2_k127_3669026_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000365 152.0
TLS2_k127_368877_0 efflux transmembrane transporter activity - - - 6.964e-201 651.0
TLS2_k127_368877_1 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 557.0
TLS2_k127_368877_2 guanyl-nucleotide exchange factor activity K01183,K20276 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000002268 259.0
TLS2_k127_368877_3 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000024 88.0
TLS2_k127_368877_4 nucleic acid-binding protein, contains PIN domain - - - 0.00004073 54.0
TLS2_k127_3726672_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 373.0
TLS2_k127_3754994_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000128 288.0
TLS2_k127_3754994_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000482 278.0
TLS2_k127_3754994_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001915 205.0
TLS2_k127_3754994_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000006297 153.0
TLS2_k127_3760628_0 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 329.0
TLS2_k127_3760628_1 pyrroloquinoline quinone binding K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000106 177.0
TLS2_k127_3767101_0 chorismate binding enzyme K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 304.0
TLS2_k127_3767101_1 PFAM regulatory protein LacI K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 265.0
TLS2_k127_3767101_2 Amino-transferase class IV K00826,K02619 - 2.6.1.42,4.1.3.38 0.00000000000000000000000000000000000000000000001487 183.0
TLS2_k127_3767101_3 FecR protein - - - 0.000000003474 70.0
TLS2_k127_3774721_0 Protein of unknown function (DUF1501) - - - 1.355e-232 726.0
TLS2_k127_3774721_1 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 334.0
TLS2_k127_3774721_2 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 313.0
TLS2_k127_3774721_3 - - - - 0.00000000000000000000000000000000005827 136.0
TLS2_k127_3774721_4 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000000005203 123.0
TLS2_k127_3774721_5 PFAM DNA polymerase, beta domain protein region K07075 - - 0.00000000000000000000006706 103.0
TLS2_k127_3780058_0 Aldehyde dehydrogenase - - - 1.357e-206 653.0
TLS2_k127_3780058_1 This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000008121 207.0
TLS2_k127_3780058_2 Belongs to the pirin family - - - 0.000000000000000000000000000000000000004061 149.0
TLS2_k127_3780058_3 Pirin - - - 0.000000000000000000000000000000000000527 143.0
TLS2_k127_3780058_4 Cupin domain - - - 0.000000000000000000000000000000203 128.0
TLS2_k127_3780058_5 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000008178 119.0
TLS2_k127_3780058_6 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.00000000000000002709 86.0
TLS2_k127_3780058_7 Zinc-binding dehydrogenase - - - 0.0000002899 57.0
TLS2_k127_3780058_8 transposition K07497 - - 0.000186 48.0
TLS2_k127_3786902_0 PFAM Uncharacterised BCR, COG1649 - - - 7.214e-240 752.0
TLS2_k127_3789467_0 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 560.0
TLS2_k127_3789467_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 445.0
TLS2_k127_3789467_2 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 432.0
TLS2_k127_3789467_3 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 296.0
TLS2_k127_3789467_4 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.000000000000000000008136 92.0
TLS2_k127_3800014_0 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 8.53e-206 649.0
TLS2_k127_3800014_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 615.0
TLS2_k127_3800014_2 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000004883 166.0
TLS2_k127_3800014_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000005652 144.0
TLS2_k127_3800014_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000009838 87.0
TLS2_k127_3804915_0 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 514.0
TLS2_k127_3804915_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 488.0
TLS2_k127_3804915_10 - - - - 0.000003906 59.0
TLS2_k127_3804915_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 484.0
TLS2_k127_3804915_3 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 433.0
TLS2_k127_3804915_4 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 321.0
TLS2_k127_3804915_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 321.0
TLS2_k127_3804915_6 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003941 287.0
TLS2_k127_3804915_7 phosphorelay sensor kinase activity K03885,K05962,K07675,K10716,K13598,K15011,K21696 - 1.6.99.3,2.7.13.1,2.7.13.3 0.000000000000000000000000000000000000000000000007501 186.0
TLS2_k127_3804915_8 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000000000000000000000000000000000000001112 171.0
TLS2_k127_3804915_9 Belongs to the glycosyl hydrolase 26 family K01218 - 3.2.1.78 0.00000000000000002389 96.0
TLS2_k127_3806550_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000001199 143.0
TLS2_k127_3806550_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000008353 101.0
TLS2_k127_3806550_2 - - - - 0.00000000000000000003365 95.0
TLS2_k127_3863597_0 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 357.0
TLS2_k127_3863597_1 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 308.0
TLS2_k127_3863597_2 Acyl-CoA dehydrogenase, N-terminal domain K00248 - 1.3.8.1 0.0000000000001259 77.0
TLS2_k127_3871710_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 457.0
TLS2_k127_3871710_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002209 250.0
TLS2_k127_3871710_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000702 196.0
TLS2_k127_3875607_0 Belongs to the LDH MDH superfamily K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 434.0
TLS2_k127_3875607_1 Aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 426.0
TLS2_k127_3875607_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000002775 154.0
TLS2_k127_3891167_0 PFAM DNA topoisomerase type IA zn finger domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 357.0
TLS2_k127_3891167_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 329.0
TLS2_k127_3891167_2 Belongs to the pirin family K06911 - - 0.000000000000000000009948 92.0
TLS2_k127_3891167_4 - - - - 0.0000152 57.0
TLS2_k127_3916115_0 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 410.0
TLS2_k127_3916115_1 Belongs to the 'phage' integrase family - - - 0.000000418 53.0
TLS2_k127_3922111_0 TIGRFAM ATP-dependent DNA helicase, RecQ family K03654 - 3.6.4.12 5.287e-267 841.0
TLS2_k127_3922111_1 DNA topoisomerase (ATP-hydrolyzing) K02470,K02622 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 574.0
TLS2_k127_3922111_2 Belongs to the type II topoisomerase GyrA ParC subunit family K02621 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 567.0
TLS2_k127_3922111_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 479.0
TLS2_k127_3922111_4 PFAM peptidase T2 asparaginase 2 K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 365.0
TLS2_k127_3922111_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 346.0
TLS2_k127_3922111_6 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 358.0
TLS2_k127_3922111_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 332.0
TLS2_k127_3922111_8 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 310.0
TLS2_k127_3922111_9 O-methyltransferase - - - 0.0000000000000000000000000001454 123.0
TLS2_k127_3935225_0 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 314.0
TLS2_k127_3935225_1 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000003225 207.0
TLS2_k127_3935225_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000003295 153.0
TLS2_k127_3935225_3 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000004862 131.0
TLS2_k127_3935225_4 phosphorelay signal transduction system - - - 0.00000000000000000000000003037 119.0
TLS2_k127_3935225_5 Domain of unknown function (DUF4160) - - - 0.00000000000000001309 85.0
TLS2_k127_3935225_6 Protein of unknown function, DUF393 - - - 0.000000000002492 73.0
TLS2_k127_3941694_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.895e-245 765.0
TLS2_k127_3941694_1 PFAM type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 429.0
TLS2_k127_3941694_10 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.0000000002033 74.0
TLS2_k127_3941694_11 FecR protein - - - 0.000000006886 65.0
TLS2_k127_3941694_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 415.0
TLS2_k127_3941694_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 317.0
TLS2_k127_3941694_4 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000007911 227.0
TLS2_k127_3941694_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000001789 188.0
TLS2_k127_3941694_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000002407 194.0
TLS2_k127_3941694_7 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000004277 202.0
TLS2_k127_3941694_8 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000009257 81.0
TLS2_k127_3941694_9 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000004385 73.0
TLS2_k127_3943855_0 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 0.0 1147.0
TLS2_k127_3943855_1 arginine decarboxylase K01585 - 4.1.1.19 6.01e-260 816.0
TLS2_k127_3943855_10 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000277 267.0
TLS2_k127_3943855_11 MobA-like NTP transferase domain K15669 - 2.7.7.71 0.000000000000000000000000000000000000000000000000000000000000000000002657 244.0
TLS2_k127_3943855_12 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000005756 236.0
TLS2_k127_3943855_13 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000002607 241.0
TLS2_k127_3943855_14 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000001401 229.0
TLS2_k127_3943855_15 endonuclease I - - - 0.00000000000000000000000000000000000000000000006524 184.0
TLS2_k127_3943855_16 Protein conserved in bacteria K07011 - - 0.00000000000000000000000000000000000000000002525 184.0
TLS2_k127_3943855_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000002408 160.0
TLS2_k127_3943855_18 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000002259 148.0
TLS2_k127_3943855_19 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000002176 141.0
TLS2_k127_3943855_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 503.0
TLS2_k127_3943855_20 MacB-like periplasmic core domain - - - 0.000000000000000000000000000006414 125.0
TLS2_k127_3943855_21 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000001178 118.0
TLS2_k127_3943855_22 small multi-drug export protein - - - 0.0005282 50.0
TLS2_k127_3943855_3 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 467.0
TLS2_k127_3943855_4 PFAM glycoside hydrolase family 39 K06113 - 3.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 457.0
TLS2_k127_3943855_5 protein conserved in bacteria K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 439.0
TLS2_k127_3943855_6 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 402.0
TLS2_k127_3943855_7 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 354.0
TLS2_k127_3943855_8 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 330.0
TLS2_k127_3943855_9 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 285.0
TLS2_k127_3950929_0 CHASE3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 524.0
TLS2_k127_3950929_1 PFAM ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000003088 196.0
TLS2_k127_3950929_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000001692 132.0
TLS2_k127_3950929_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000973 121.0
TLS2_k127_3950929_4 BON domain - - - 0.0000000000000000000002249 101.0
TLS2_k127_3950929_5 Protein of unknown function (DUF3185) - - - 0.000000000000000000001191 98.0
TLS2_k127_3950929_6 - - - - 0.000000000000001371 77.0
TLS2_k127_3950929_7 PurA ssDNA and RNA-binding protein - - - 0.000000000000003262 87.0
TLS2_k127_3950929_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00003749 48.0
TLS2_k127_3951782_0 Short-chain dehydrogenase reductase SDR K17754 - 1.1.1.163 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008222 278.0
TLS2_k127_3951782_1 Dimerisation domain - - - 0.00000000000000000000000002309 118.0
TLS2_k127_3951782_2 Ureidoglycolate lyase K01483 - 4.3.2.3 0.000001676 59.0
TLS2_k127_3956714_0 - - - - 8.069e-223 721.0
TLS2_k127_3956714_1 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 436.0
TLS2_k127_3956714_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000003532 157.0
TLS2_k127_395910_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000235 291.0
TLS2_k127_395910_1 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000000000000000000003761 159.0
TLS2_k127_395910_2 PRC-barrel domain - - - 0.0000000000000000002603 101.0
TLS2_k127_395910_3 Bacterial-like globin - - - 0.000000000000000006218 94.0
TLS2_k127_395910_4 PDZ domain (Also known as DHR or GLGF) - - - 0.0000264 51.0
TLS2_k127_3964442_0 Putative zinc binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 520.0
TLS2_k127_3964442_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 458.0
TLS2_k127_3964442_2 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000002108 186.0
TLS2_k127_3964442_3 Histidine kinase - - - 0.0000000000000000000003516 109.0
TLS2_k127_3964442_4 response regulator K02481,K07713 - - 0.000000000000000000008315 98.0
TLS2_k127_3964442_5 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000001946 83.0
TLS2_k127_3964442_6 Carbamoyltransferase N-terminus K00612 - - 0.00000000563 60.0
TLS2_k127_3979334_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 441.0
TLS2_k127_3979334_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 439.0
TLS2_k127_3979334_2 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 381.0
TLS2_k127_3979334_3 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 381.0
TLS2_k127_3979334_4 Nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000009233 259.0
TLS2_k127_3979334_5 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001018 255.0
TLS2_k127_3979334_6 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000004356 186.0
TLS2_k127_3979334_7 - - - - 0.0000000000000000000000000000000000000008497 161.0
TLS2_k127_3979334_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000003422 102.0
TLS2_k127_3979334_9 Polymer-forming cytoskeletal - - - 0.000000000000000000002129 102.0
TLS2_k127_3980967_0 periplasmic protein - - - 0.000000000000000000000000000000000000000000000000000000004911 202.0
TLS2_k127_3980967_1 Polymer-forming cytoskeletal - - - 0.0000000000000000000000001659 110.0
TLS2_k127_3982549_0 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 6.916e-237 762.0
TLS2_k127_3982549_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000000000000001625 190.0
TLS2_k127_403005_0 Peroxidase - - - 0.0 1247.0
TLS2_k127_403005_1 PFAM glycoside hydrolase family 39 K01198 - 3.2.1.37 2.615e-237 746.0
TLS2_k127_403005_10 Type ii and iii secretion system protein K02666 - - 0.0002841 48.0
TLS2_k127_403005_11 - - - - 0.00055 46.0
TLS2_k127_403005_2 Belongs to the glycosyl hydrolase 43 family K01198,K01209 - 3.2.1.37,3.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 374.0
TLS2_k127_403005_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 319.0
TLS2_k127_403005_4 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000002097 168.0
TLS2_k127_403005_5 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000001291 158.0
TLS2_k127_403005_6 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000009791 151.0
TLS2_k127_403005_7 - - - - 0.000000000000000000000000000000004637 145.0
TLS2_k127_403005_8 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000004846 102.0
TLS2_k127_403005_9 TatD-related deoxyribonuclease K03424 - - 0.000000002213 61.0
TLS2_k127_4030703_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 375.0
TLS2_k127_4030703_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000003525 233.0
TLS2_k127_4030703_2 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001818 236.0
TLS2_k127_4030703_3 RNA polymerase sigma factor, sigma-70 family - - - 0.000000000000000000000000000000000000000000001216 183.0
TLS2_k127_4030703_4 response to abiotic stimulus K06867 - - 0.00003882 57.0
TLS2_k127_4087263_0 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 554.0
TLS2_k127_4087263_1 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 468.0
TLS2_k127_4087263_12 Belongs to the 'phage' integrase family K04763 - - 0.00000002158 64.0
TLS2_k127_4087263_2 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 293.0
TLS2_k127_4087263_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007893 278.0
TLS2_k127_4087263_4 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000001181 248.0
TLS2_k127_4087263_5 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000003511 220.0
TLS2_k127_4087263_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000000000000000000005439 151.0
TLS2_k127_4087263_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000004895 132.0
TLS2_k127_4087263_8 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000001148 117.0
TLS2_k127_4087263_9 methyltransferase K02853,K12582 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008417,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0036065,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576 2.4.1.325 0.000000000000000000000003913 112.0
TLS2_k127_4088869_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 592.0
TLS2_k127_4088869_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 530.0
TLS2_k127_4088869_10 cell wall surface anchor family protein - - - 0.000000000000000000000000007224 128.0
TLS2_k127_4088869_11 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000006657 99.0
TLS2_k127_4088869_12 Hep Hag repeat protein K11904,K21449 - - 0.00000000000000000005656 106.0
TLS2_k127_4088869_14 Hep Hag repeat protein - - - 0.00000000015 74.0
TLS2_k127_4088869_15 FHA domain protein - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.0000000009606 70.0
TLS2_k127_4088869_16 Protein of unknown function (DUF465) K09794 - - 0.000000001351 61.0
TLS2_k127_4088869_17 cell wall surface anchor family protein - - - 0.000001455 56.0
TLS2_k127_4088869_19 domain, Protein K11904,K12132 - 2.7.11.1 0.0007388 49.0
TLS2_k127_4088869_2 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 512.0
TLS2_k127_4088869_3 Nucleoside recognition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 379.0
TLS2_k127_4088869_4 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 344.0
TLS2_k127_4088869_5 carboxypeptidase activity K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004501 280.0
TLS2_k127_4088869_6 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000000000000004115 231.0
TLS2_k127_4088869_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000008334 176.0
TLS2_k127_4088869_8 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000002136 159.0
TLS2_k127_4088869_9 - - - - 0.0000000000000000000000000000000000003627 160.0
TLS2_k127_4092705_0 biotin synthase activity K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 335.0
TLS2_k127_4092705_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 309.0
TLS2_k127_4092705_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000008714 194.0
TLS2_k127_4092705_3 Subtilase family - - - 0.0000000000000000000000000000000000000000000027 192.0
TLS2_k127_4092705_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000001453 171.0
TLS2_k127_4092705_5 - - - - 0.0000000004924 68.0
TLS2_k127_4092705_6 Prokaryotic N-terminal methylation motif - - - 0.000007295 55.0
TLS2_k127_4092705_7 Type II transport protein GspH - - - 0.0001244 53.0
TLS2_k127_4092705_8 - - - - 0.0002345 49.0
TLS2_k127_4098680_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001129 290.0
TLS2_k127_4098680_1 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000003479 222.0
TLS2_k127_4098680_2 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000004785 154.0
TLS2_k127_4098680_3 Protein of unknown function, DUF393 - - - 0.00000000000005846 76.0
TLS2_k127_4098680_4 - - - - 0.000000000005178 67.0
TLS2_k127_4098680_5 - - - - 0.0002377 46.0
TLS2_k127_4113888_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1391.0
TLS2_k127_4113888_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.344e-292 925.0
TLS2_k127_4113888_10 general secretion pathway protein D K02453 - - 0.00000000000000000000000000000000000000000991 168.0
TLS2_k127_4113888_11 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000011 149.0
TLS2_k127_4113888_12 PFAM response regulator receiver - - - 0.000000000000000000000000000005457 127.0
TLS2_k127_4113888_13 Bacterial type II/III secretion system short domain - - - 0.000000000003564 79.0
TLS2_k127_4113888_15 Type II secretion system (T2SS), protein J K02459 - - 0.000005131 57.0
TLS2_k127_4113888_16 General secretion pathway protein I K02458 - - 0.0001086 51.0
TLS2_k127_4113888_17 COG4970 Tfp pilus assembly protein FimT K08084,K08085 - - 0.0001643 51.0
TLS2_k127_4113888_2 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 527.0
TLS2_k127_4113888_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 504.0
TLS2_k127_4113888_4 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 341.0
TLS2_k127_4113888_5 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 314.0
TLS2_k127_4113888_6 Two component transcriptional regulator, winged helix family K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 299.0
TLS2_k127_4113888_7 Type 4 fimbrial assembly protein pilC K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000002673 241.0
TLS2_k127_4113888_8 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000001642 184.0
TLS2_k127_4113888_9 Type II secretion system (T2SS), protein K - - - 0.000000000000000000000000000000000000000000002027 183.0
TLS2_k127_4118466_0 glutamate synthase K00284 - 1.4.7.1 0.0 2043.0
TLS2_k127_4118466_1 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 4.461e-215 674.0
TLS2_k127_4132979_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1092.0
TLS2_k127_4132979_1 3-isopropylmalate dehydratase, small subunit K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000002823 248.0
TLS2_k127_4132979_2 COG0265 Trypsin-like serine proteases, typically periplasmic K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000623 215.0
TLS2_k127_4132979_4 - - - - 0.000000000000000000000000001772 119.0
TLS2_k127_4132979_5 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000001341 88.0
TLS2_k127_4136692_0 Peptidase U32 K08303 - - 2.602e-235 744.0
TLS2_k127_4136692_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 2.202e-233 731.0
TLS2_k127_4136692_2 cellulose binding - - - 4.333e-217 678.0
TLS2_k127_4136692_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000008981 223.0
TLS2_k127_4136692_4 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000000000000000002106 190.0
TLS2_k127_4136692_5 YCII-related domain - - - 0.000000000000000000000000000000000000000000007405 166.0
TLS2_k127_4136692_6 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000006387 159.0
TLS2_k127_4136692_7 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000003387 143.0
TLS2_k127_4153431_0 Pectate lyase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 411.0
TLS2_k127_4153431_1 Male sterility protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 358.0
TLS2_k127_4153431_10 Pfam:N_methyl_2 - - - 0.0000000000002602 79.0
TLS2_k127_4153431_11 Putative collagen-binding domain of a collagenase - - - 0.0000000000216 69.0
TLS2_k127_4153431_12 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000008421 75.0
TLS2_k127_4153431_13 Lysine exporter protein LysE YggA - - - 0.00000000009383 72.0
TLS2_k127_4153431_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003937 286.0
TLS2_k127_4153431_3 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.00000000000000000000000000000000000000000000000000000000000000000006666 240.0
TLS2_k127_4153431_4 RNase_H superfamily K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000366 221.0
TLS2_k127_4153431_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000002452 181.0
TLS2_k127_4153431_6 cell wall hydrolase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000009024 168.0
TLS2_k127_4153431_7 polysaccharide catabolic process K19049 - 4.2.2.5 0.000000000000000000000000000000000005784 155.0
TLS2_k127_4153431_8 - - - - 0.000000000000000000000000000000000681 140.0
TLS2_k127_4153431_9 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000000000408 88.0
TLS2_k127_4163174_0 Transketolase, pyrimidine binding domain K00161,K00162,K00167,K11381 - 1.2.4.1,1.2.4.4 2.047e-282 878.0
TLS2_k127_4163174_1 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 310.0
TLS2_k127_4163174_2 - - - - 0.0000000000000000000000000000000000001003 149.0
TLS2_k127_4163174_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000003013 85.0
TLS2_k127_4167799_0 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.0000000000000002119 89.0
TLS2_k127_4191771_0 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 382.0
TLS2_k127_4191771_1 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002631 278.0
TLS2_k127_4191771_2 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000001004 229.0
TLS2_k127_4191771_3 Flavoprotein K01598 - 4.1.1.36 0.000000000000000000000000000000000000000000000000000000000000003825 221.0
TLS2_k127_4191771_4 Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000004114 221.0
TLS2_k127_4191771_5 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000001701 192.0
TLS2_k127_4191771_6 Guanylate kinase K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000001221 176.0
TLS2_k127_4191771_7 Histidine kinase - - - 0.000000000000000000000000000001161 137.0
TLS2_k127_4191771_8 EamA-like transporter family - - - 0.0000000000000000000001531 102.0
TLS2_k127_4220009_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 436.0
TLS2_k127_4220009_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 352.0
TLS2_k127_4220009_2 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000000000000000000000000000002165 154.0
TLS2_k127_4220009_3 hydroxyacid-oxoacid transhydrogenase activity K00001,K01714 - 1.1.1.1,4.3.3.7 0.00000000000003191 74.0
TLS2_k127_4221571_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 506.0
TLS2_k127_4221571_1 Glycosyl hydrolase family 20, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 490.0
TLS2_k127_4221571_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 457.0
TLS2_k127_4221571_3 Pfam:N_methyl_2 - - - 0.00000000000001854 84.0
TLS2_k127_4221571_4 DNA methylase K07316 - 2.1.1.72 0.0005311 42.0
TLS2_k127_4225375_0 sequence-specific DNA binding K03555,K16328 - 2.7.1.83 1.446e-207 669.0
TLS2_k127_4225375_1 mevalonate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 465.0
TLS2_k127_4225375_2 PFAM iron-containing alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 449.0
TLS2_k127_4225375_3 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000006078 198.0
TLS2_k127_4225375_4 PFAM Plasmid pRiA4b ORF-3-like protein - - - 0.0000000000000000000000000000000000000000004138 166.0
TLS2_k127_4225375_5 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000001691 133.0
TLS2_k127_4225375_6 Protein of unknown function (DUF433) - - - 0.0000000000000000000003444 97.0
TLS2_k127_4225375_7 HNH endonuclease K07454 - - 0.000000000000000004754 88.0
TLS2_k127_4225375_8 - - - - 0.0000004555 58.0
TLS2_k127_422816_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 357.0
TLS2_k127_422816_1 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 323.0
TLS2_k127_422816_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000002257 230.0
TLS2_k127_422816_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000007896 159.0
TLS2_k127_422816_4 Glutathione peroxidase - - - 0.0000000000000000000000004602 106.0
TLS2_k127_4244180_0 response to antibiotic - - - 3.716e-199 681.0
TLS2_k127_4244180_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 445.0
TLS2_k127_4244180_2 Protein of unknown function (DUF1349) K09702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001091 256.0
TLS2_k127_4244180_3 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000008835 171.0
TLS2_k127_4244180_4 - - - - 0.00000000000000000000000000000000000003625 162.0
TLS2_k127_4244180_5 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000002872 142.0
TLS2_k127_4244180_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000002539 128.0
TLS2_k127_4244180_7 Glycosyl hydrolase family 92 - - - 0.000000000002214 82.0
TLS2_k127_4244180_8 long-chain fatty acid transport protein - - - 0.000002998 58.0
TLS2_k127_4244180_9 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0005311 42.0
TLS2_k127_4265108_0 phosphorelay signal transduction system - - - 1.212e-243 779.0
TLS2_k127_4265108_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 493.0
TLS2_k127_4265108_2 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 460.0
TLS2_k127_4265108_3 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 331.0
TLS2_k127_4265108_4 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000000002412 250.0
TLS2_k127_4265108_5 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000000003681 216.0
TLS2_k127_4265108_6 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000002054 182.0
TLS2_k127_4265108_7 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 0.00000000008227 75.0
TLS2_k127_4293833_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 6.407e-199 630.0
TLS2_k127_4293833_1 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 550.0
TLS2_k127_4293833_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000002531 175.0
TLS2_k127_4293833_3 - - - - 0.0000002046 61.0
TLS2_k127_4297469_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 437.0
TLS2_k127_4297469_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 370.0
TLS2_k127_4297469_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000231 211.0
TLS2_k127_4297469_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000001448 92.0
TLS2_k127_4297469_4 - - - - 0.000000000000002122 91.0
TLS2_k127_4297469_5 ABC-2 family transporter protein - - - 0.00001821 59.0
TLS2_k127_4297469_6 AsmA-like C-terminal region K07289 - - 0.00003131 58.0
TLS2_k127_4297469_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0006036 50.0
TLS2_k127_4297469_8 AsmA family K07289 - - 0.0008531 53.0
TLS2_k127_4316306_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002517 260.0
TLS2_k127_4316306_1 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000003059 78.0
TLS2_k127_433693_0 Anticodon binding domain K01880 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 494.0
TLS2_k127_433693_1 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 466.0
TLS2_k127_433693_2 Domain of unknown function (DUF4339) - - - 0.0000000000007318 80.0
TLS2_k127_4351840_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 476.0
TLS2_k127_4351840_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000002661 205.0
TLS2_k127_4351840_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000008187 188.0
TLS2_k127_4351840_3 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.000000000000000000000000000000000000000000000002142 182.0
TLS2_k127_4351840_4 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.00000000000000000000001098 108.0
TLS2_k127_4368978_0 ATPase involved in DNA repair - - - 0.0 1784.0
TLS2_k127_4368978_1 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 573.0
TLS2_k127_4368978_2 Band 7 protein K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 567.0
TLS2_k127_4368978_3 unsaturated chondroitin disaccharide hydrolase activity K01795 - 5.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 529.0
TLS2_k127_4368978_4 COGs COG0673 dehydrogenase and related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002729 293.0
TLS2_k127_4368978_5 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000004169 63.0
TLS2_k127_4373102_0 3-demethylubiquinone-9 3-O-methyltransferase activity K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 377.0
TLS2_k127_4373102_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000007794 241.0
TLS2_k127_438582_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 310.0
TLS2_k127_438582_1 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000003586 145.0
TLS2_k127_438582_2 Phosphorylase superfamily - - - 0.0000000000000000000000000008392 115.0
TLS2_k127_438582_3 Protein of unknown function (DUF1559) - - - 0.00000000000004912 81.0
TLS2_k127_4389352_0 CotH kinase protein - - - 5.94e-245 788.0
TLS2_k127_4389635_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 536.0
TLS2_k127_4389635_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 492.0
TLS2_k127_4389635_2 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 466.0
TLS2_k127_4389635_3 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000002616 198.0
TLS2_k127_4389635_4 Rhomboid family K02441 - - 0.00000000000000000000000000000000000000001147 163.0
TLS2_k127_4389635_5 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000007316 82.0
TLS2_k127_4389699_0 Carboxypeptidase regulatory-like domain - - - 1.03e-208 665.0
TLS2_k127_4389699_1 PFAM single-strand binding protein Primosomal replication protein n K03111 - - 0.00000000000000000000000000002885 125.0
TLS2_k127_4389699_2 Tetratricopeptide repeat - - - 0.000003635 58.0
TLS2_k127_4393638_0 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 342.0
TLS2_k127_4393638_1 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000007192 255.0
TLS2_k127_4393638_2 - - - - 0.000000000000000000000000000000000000000000000000000000002069 218.0
TLS2_k127_4393638_3 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000005994 219.0
TLS2_k127_4393638_4 MlaD protein K06192 - - 0.000000000000000000000000000000000000001866 156.0
TLS2_k127_4393638_5 Protein conserved in bacteria K18480 - - 0.00000000000000000000000000000000002056 143.0
TLS2_k127_4393638_6 Glucose / Sorbosone dehydrogenase K00428,K01728 - 1.11.1.5,4.2.2.2 0.000000000000000000001576 112.0
TLS2_k127_439368_0 Protein of unknown function (DUF1501) - - - 1.286e-231 727.0
TLS2_k127_439368_1 Protein of unknown function (DUF1549) - - - 9.847e-200 642.0
TLS2_k127_439368_2 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004833 252.0
TLS2_k127_4406582_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 508.0
TLS2_k127_4406582_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001477 235.0
TLS2_k127_4406582_2 Cobalt uptake substrate-specific transmembrane region - - - 0.0000000000000006564 83.0
TLS2_k127_4408037_0 AcrB/AcrD/AcrF family - - - 0.0 1322.0
TLS2_k127_4408037_1 Tryptophan halogenase - - - 7.223e-233 734.0
TLS2_k127_4408037_10 Rnk N-terminus K06140 - - 0.0000000000000000000000000000000000001628 145.0
TLS2_k127_4408037_11 SMART regulatory protein ArsR - - - 0.0000000000000000000000000000005459 128.0
TLS2_k127_4408037_12 Subtilase family - - - 0.000000000000000000000002205 118.0
TLS2_k127_4408037_13 Thioredoxin domain - - - 0.00000000000000002681 88.0
TLS2_k127_4408037_14 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000001051 76.0
TLS2_k127_4408037_15 general secretion pathway protein K02456,K02650,K02679 - - 0.00000000000908 76.0
TLS2_k127_4408037_2 alpha beta - - - 9.91e-230 739.0
TLS2_k127_4408037_3 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 567.0
TLS2_k127_4408037_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 439.0
TLS2_k127_4408037_5 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 434.0
TLS2_k127_4408037_6 RNA polymerase recycling family C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 346.0
TLS2_k127_4408037_7 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 322.0
TLS2_k127_4408037_8 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000002045 199.0
TLS2_k127_4408037_9 enzyme related to lactoylglutathione lyase K06996 - - 0.000000000000000000000000000000000000001646 149.0
TLS2_k127_4452913_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 2.642e-256 807.0
TLS2_k127_4452913_1 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 338.0
TLS2_k127_4452913_2 2Fe-2S -binding domain protein K13483 - - 0.00000000000000000000000000000000000000000000000000000000000001768 222.0
TLS2_k127_4452913_3 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000001815 180.0
TLS2_k127_4452913_4 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000000000000000000000000003923 136.0
TLS2_k127_4452913_5 Protein of unknown function (DUF1326) - - - 0.00000000000000001348 92.0
TLS2_k127_4459396_0 inositol 2-dehydrogenase activity - - - 1.862e-286 898.0
TLS2_k127_4459396_1 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 410.0
TLS2_k127_4459396_2 UDP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005996 273.0
TLS2_k127_4459396_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000005997 181.0
TLS2_k127_4479488_0 Belongs to the 'phage' integrase family K04763 - - 0.00000000001219 72.0
TLS2_k127_4493655_0 Fructose-bisphosphate aldolase class K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 587.0
TLS2_k127_4493655_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 336.0
TLS2_k127_4493655_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007647 235.0
TLS2_k127_4493655_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000003889 206.0
TLS2_k127_4495649_0 Molybdopterin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 527.0
TLS2_k127_4495649_1 Cytochrome c K00373,K00405,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 417.0
TLS2_k127_4495649_2 pathogenesis - - - 0.0000000000000000000000000000000000048 145.0
TLS2_k127_4495649_3 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000001382 130.0
TLS2_k127_4495649_4 VTC domain - - - 0.00000000000000000000000000006059 126.0
TLS2_k127_4515490_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000695 283.0
TLS2_k127_4515490_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004643 258.0
TLS2_k127_4515490_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000008076 235.0
TLS2_k127_4515490_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000004325 124.0
TLS2_k127_4515490_4 TniQ - - - 0.00000000000001125 86.0
TLS2_k127_4516438_0 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 595.0
TLS2_k127_4516438_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 451.0
TLS2_k127_4516438_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 320.0
TLS2_k127_4516438_3 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000005511 197.0
TLS2_k127_4538744_0 Carbamoyltransferase C-terminus K00612 - - 4.354e-237 747.0
TLS2_k127_4538744_1 winged helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 462.0
TLS2_k127_4538744_2 PFAM Glycosyl transferases group 1 K16703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 297.0
TLS2_k127_4538744_3 - - - - 0.000000000000000000000000000000000000000000000000001111 194.0
TLS2_k127_4538744_4 - - - - 0.0006397 52.0
TLS2_k127_4557590_0 L-fucose isomerase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 336.0
TLS2_k127_4557590_1 - - - - 0.00000000000000000000000000000000000000000000000002241 190.0
TLS2_k127_4557590_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000001102 153.0
TLS2_k127_4557926_0 metallocarboxypeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001371 293.0
TLS2_k127_4557926_1 Glycosyl hydrolases family 43 - - - 0.0000000000000000000000000000000000000000000000456 184.0
TLS2_k127_4557926_2 acid phosphatase activity K01126 - 3.1.4.46 0.0000000000000000000000001921 124.0
TLS2_k127_4575586_0 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 1.714e-216 684.0
TLS2_k127_4575586_1 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 610.0
TLS2_k127_4575586_2 Glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 330.0
TLS2_k127_460046_0 Peptidase S46 - - - 1.094e-253 800.0
TLS2_k127_460046_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.823e-237 740.0
TLS2_k127_460046_2 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 5.136e-229 722.0
TLS2_k127_460046_3 heme-binding domain, Pirellula Verrucomicrobium type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 343.0
TLS2_k127_460046_4 Cellulase (glycosyl hydrolase family 5) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 358.0
TLS2_k127_460046_5 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003506 282.0
TLS2_k127_460046_6 NHL repeat - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0010196,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:1990066 - 0.000000000000000000000000000000000000000000000000001312 201.0
TLS2_k127_460046_7 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000001104 147.0
TLS2_k127_460046_8 CAAX protease self-immunity K07052 - - 0.000000000000000000000000002272 127.0
TLS2_k127_460046_9 - - - - 0.0000000000000000000003241 101.0
TLS2_k127_4605200_0 ASPIC UnbV domain protein - - - 4.579e-272 878.0
TLS2_k127_4605200_1 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 550.0
TLS2_k127_4605200_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 405.0
TLS2_k127_4605200_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 396.0
TLS2_k127_4605200_4 with different specificities (related to short-chain alcohol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 308.0
TLS2_k127_4605200_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000009372 198.0
TLS2_k127_4645532_0 Transposase - - - 3.485e-248 769.0
TLS2_k127_4645532_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 426.0
TLS2_k127_46494_0 -transport system K01992 - - 0.00000000000000000000000009345 119.0
TLS2_k127_46494_1 Domain of unknown function (DUF4340) - - - 0.000000000000001043 91.0
TLS2_k127_46494_2 AsmA-like C-terminal region - - - 0.000000001144 72.0
TLS2_k127_4650339_0 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000409 282.0
TLS2_k127_4650339_1 Cupin 2, conserved barrel - - - 0.000000000000000000000000000000005493 134.0
TLS2_k127_4650339_2 Translation initiation inhibitor, yjgF family - - - 0.000000000000000000000001857 103.0
TLS2_k127_4650339_3 short-chain dehydrogenase - - - 0.000000000000000009756 84.0
TLS2_k127_4650339_4 Antibiotic biosynthesis monooxygenase - - - 0.000000001166 67.0
TLS2_k127_4650339_5 - - - - 0.000001129 53.0
TLS2_k127_4658715_0 Protein of unknown function (DUF4038) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 614.0
TLS2_k127_4658715_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 460.0
TLS2_k127_4658715_2 Glycosyl hydrolase, family 20, catalytic domain - - - 0.000000000000000000000000000000000000000000000002712 180.0
TLS2_k127_4658715_3 Glucose sorbosone - - - 0.00000000001906 76.0
TLS2_k127_4658715_4 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000106 73.0
TLS2_k127_4671483_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 500.0
TLS2_k127_4671483_1 domain, Protein - - - 0.00000005216 61.0
TLS2_k127_4674840_0 - - - - 0.0000000000000000000000000000000000000000000000000000000008098 204.0
TLS2_k127_4674840_1 Cobalamin adenosyltransferase - - - 0.0000000000000000000000000000000000000000000003669 175.0
TLS2_k127_4674840_2 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.000000000001976 78.0
TLS2_k127_4674840_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000009881 50.0
TLS2_k127_4691738_0 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 399.0
TLS2_k127_4691738_1 PFAM Metallophosphoesterase K07096 - - 0.0000000000000000000000000000007033 138.0
TLS2_k127_4691738_2 E-Z type HEAT repeats - - - 0.0000000000000000000001342 110.0
TLS2_k127_4700636_0 PFAM MgtE intracellular K02383 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 398.0
TLS2_k127_4701956_0 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 343.0
TLS2_k127_4701956_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000009638 170.0
TLS2_k127_4701956_2 general secretion pathway protein K02456,K02679 - - 0.00000001796 64.0
TLS2_k127_4705689_0 COG3119 Arylsulfatase A - - - 5.548e-254 792.0
TLS2_k127_4705689_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 488.0
TLS2_k127_4705689_2 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000008389 239.0
TLS2_k127_4705689_3 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000008344 168.0
TLS2_k127_4712967_0 beta-1,4-mannooligosaccharide phosphorylase K20885 - 2.4.1.339,2.4.1.340 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 385.0
TLS2_k127_4712967_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 400.0
TLS2_k127_4712967_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000026 153.0
TLS2_k127_4712967_3 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.0000000000000000000000000000000824 126.0
TLS2_k127_4718773_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 448.0
TLS2_k127_4718773_1 Carbohydrate esterase, sialic acid-specific acetylesterase K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000001173 188.0
TLS2_k127_4723956_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 485.0
TLS2_k127_4723956_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 458.0
TLS2_k127_4723956_10 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004262 265.0
TLS2_k127_4723956_11 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000008273 195.0
TLS2_k127_4723956_12 ACT domain - - - 0.0000000000000000000000000000000000000000000000001692 182.0
TLS2_k127_4723956_13 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.000000000000000000000000000000000001806 139.0
TLS2_k127_4723956_14 regulation of translation K03530 - - 0.00000000000000000000000000000000148 131.0
TLS2_k127_4723956_15 CAAX amino terminal protease K07052 - - 0.0000000000000000000000000000001709 130.0
TLS2_k127_4723956_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000007935 104.0
TLS2_k127_4723956_17 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000001336 109.0
TLS2_k127_4723956_18 membrane transporter protein K07090 - - 0.0000000000000000001912 95.0
TLS2_k127_4723956_19 Tetratricopeptide repeat - - - 0.000000001374 72.0
TLS2_k127_4723956_2 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 433.0
TLS2_k127_4723956_3 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 425.0
TLS2_k127_4723956_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 412.0
TLS2_k127_4723956_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01885,K01894 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 383.0
TLS2_k127_4723956_6 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 348.0
TLS2_k127_4723956_7 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 307.0
TLS2_k127_4723956_8 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001115 277.0
TLS2_k127_4723956_9 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000006626 260.0
TLS2_k127_4731419_0 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 567.0
TLS2_k127_4731419_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 519.0
TLS2_k127_4731419_2 Phosphoenolpyruvate hydrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 485.0
TLS2_k127_4731419_3 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 293.0
TLS2_k127_4734088_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.339e-251 787.0
TLS2_k127_4734088_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 2.164e-251 811.0
TLS2_k127_4734088_2 PFAM MscS Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 346.0
TLS2_k127_4734088_3 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001546 243.0
TLS2_k127_4734088_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.000000000000000000000000000000000000000000000000000000000006839 221.0
TLS2_k127_4734088_5 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000007832 181.0
TLS2_k127_4734088_6 efflux transmembrane transporter activity K18903 - - 0.0000000000000000000000000000000000000000000001586 172.0
TLS2_k127_4734088_7 Major facilitator Superfamily - - - 0.00003567 56.0
TLS2_k127_4749014_0 - - - - 2.903e-204 654.0
TLS2_k127_4749014_1 Protein of unknown function (DUF1587) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 613.0
TLS2_k127_4749014_2 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 539.0
TLS2_k127_4749014_3 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 297.0
TLS2_k127_4749014_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000001561 192.0
TLS2_k127_4749014_5 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000915 180.0
TLS2_k127_4749014_6 Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000001112 85.0
TLS2_k127_4755619_0 TIGRFAM cysteine desulfurase family protein - - - 0.00000000000000000000000000000000000005726 147.0
TLS2_k127_4755619_1 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000025 94.0
TLS2_k127_4816021_0 peptidyl-tyrosine sulfation - - - 6.511e-312 990.0
TLS2_k127_4816021_1 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 311.0
TLS2_k127_4816021_2 LexA DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000002732 197.0
TLS2_k127_4816021_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000001743 196.0
TLS2_k127_4816021_4 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000005172 124.0
TLS2_k127_4816021_5 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.00000000006855 69.0
TLS2_k127_4816021_6 Transposase IS200 like K07491 - - 0.000000009729 57.0
TLS2_k127_4834600_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 2.309e-201 639.0
TLS2_k127_4834600_1 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 454.0
TLS2_k127_4834600_10 Dihydroneopterin aldolase - - - 0.000000000003659 68.0
TLS2_k127_4834600_11 Putative molybdenum carrier - - - 0.000001086 54.0
TLS2_k127_4834600_12 - - - - 0.000002284 57.0
TLS2_k127_4834600_13 - - - - 0.00005674 51.0
TLS2_k127_4834600_2 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 456.0
TLS2_k127_4834600_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 371.0
TLS2_k127_4834600_4 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001293 240.0
TLS2_k127_4834600_5 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000004774 222.0
TLS2_k127_4834600_6 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000000000000000000000000000001714 211.0
TLS2_k127_4834600_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000001031 183.0
TLS2_k127_4834600_9 glycosyl transferase family 2 - - - 0.0000000000000000000000000000001208 129.0
TLS2_k127_4844026_0 PFAM 4Fe-4S K00184,K21308 - - 0.0 1082.0
TLS2_k127_4844026_1 Polysulphide reductase, NrfD K00185 - - 5.326e-209 661.0
TLS2_k127_4844026_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 378.0
TLS2_k127_4844026_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 289.0
TLS2_k127_4844026_4 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000005815 226.0
TLS2_k127_4844026_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000002851 226.0
TLS2_k127_4844026_6 - - - - 0.0000000000001716 77.0
TLS2_k127_4861592_0 COG3263 NhaP-type Na H and K H K11105 - - 3.817e-227 717.0
TLS2_k127_4861592_1 Belongs to the binding-protein-dependent transport system permease family K10440,K10559,K10561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 424.0
TLS2_k127_4861592_2 ECF sigma factor - - - 0.00000000000000000000000000000000001499 139.0
TLS2_k127_4865499_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 542.0
TLS2_k127_4865499_1 ISPsy14, transposition helper protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 287.0
TLS2_k127_4865499_2 - K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000001577 191.0
TLS2_k127_4865499_3 - - - - 0.000000000000000000000000000000000000000000000003736 181.0
TLS2_k127_4865499_4 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000002929 167.0
TLS2_k127_4865499_5 - - - - 0.0004987 51.0
TLS2_k127_4870020_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 533.0
TLS2_k127_4870020_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 528.0
TLS2_k127_4870020_10 Protein kinase domain K12132 - 2.7.11.1 0.0002446 53.0
TLS2_k127_4870020_2 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 490.0
TLS2_k127_4870020_3 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 352.0
TLS2_k127_4870020_4 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 316.0
TLS2_k127_4870020_5 PFAM Glycosyl transferase, group 1 K02844 - - 0.00000000000000000000000000000000000000000003449 177.0
TLS2_k127_4870020_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000003308 149.0
TLS2_k127_4870020_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000009842 143.0
TLS2_k127_4870020_8 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000002962 123.0
TLS2_k127_4870020_9 protein kinase activity - - - 0.0000000000000006155 89.0
TLS2_k127_4873222_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 481.0
TLS2_k127_4873222_1 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001005 293.0
TLS2_k127_4873222_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000004965 246.0
TLS2_k127_4873222_3 Hep Hag repeat protein - - - 0.00000000000000000009805 98.0
TLS2_k127_4875481_0 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 411.0
TLS2_k127_4875481_1 galactose-1-phosphate K00965 - 2.7.7.12 0.0000000000000002581 79.0
TLS2_k127_4879374_0 Tricorn protease C1 domain K08676 - - 0.0 1343.0
TLS2_k127_4879374_1 MacB-like periplasmic core domain - - - 6.202e-261 830.0
TLS2_k127_4879374_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 512.0
TLS2_k127_4879374_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 335.0
TLS2_k127_4879374_4 Binding-protein-dependent transport system inner membrane component K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000016 256.0
TLS2_k127_4879374_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003946 239.0
TLS2_k127_4879374_6 Ami_3 K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.000000004072 68.0
TLS2_k127_4900683_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1423.0
TLS2_k127_4900683_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1116.0
TLS2_k127_4903097_0 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 497.0
TLS2_k127_4903097_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000002446 197.0
TLS2_k127_4903097_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000002317 130.0
TLS2_k127_4910265_0 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 459.0
TLS2_k127_4910265_1 xylose isomerase activity K01805 - 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 382.0
TLS2_k127_4910265_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 332.0
TLS2_k127_4910265_3 sulfuric ester hydrolase activity - - - 0.0000000000000000000000000000000002114 140.0
TLS2_k127_4910265_4 membrane - - - 0.000000000000000000000000000000008582 136.0
TLS2_k127_4925994_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 488.0
TLS2_k127_4925994_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 422.0
TLS2_k127_4925994_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 423.0
TLS2_k127_4925994_3 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.000000000000000000000000000000000000000000000000000004747 195.0
TLS2_k127_4925994_4 Thioredoxin-like - - - 0.0000000000000000115 96.0
TLS2_k127_4925994_5 Beta-galactosidase - - - 0.0000000000002607 83.0
TLS2_k127_4925994_6 Flavin reductase like domain - - - 0.0000005113 51.0
TLS2_k127_4938569_0 PFAM CheB methylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 312.0
TLS2_k127_4938569_1 HWE histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000274 259.0
TLS2_k127_4938569_2 Response regulator, receiver - - - 0.000000000000000000000000000004504 123.0
TLS2_k127_4938569_3 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000001411 82.0
TLS2_k127_4939509_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 430.0
TLS2_k127_4939509_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 389.0
TLS2_k127_4939509_2 amine dehydrogenase activity K01179,K01729,K09942 - 3.2.1.4,4.2.2.3 0.000000000000000000000000000000001266 135.0
TLS2_k127_4941150_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 430.0
TLS2_k127_4941150_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 371.0
TLS2_k127_4941150_10 - - - - 0.000009836 55.0
TLS2_k127_4941150_2 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 352.0
TLS2_k127_4941150_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005446 272.0
TLS2_k127_4941150_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007572 268.0
TLS2_k127_4941150_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000006863 215.0
TLS2_k127_4941150_6 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.0000000000000000000000000000000000000000000000001003 183.0
TLS2_k127_4941150_7 EVE domain - - - 0.00000000000000000000000000000000000000000006757 163.0
TLS2_k127_4941150_8 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000001511 109.0
TLS2_k127_4941150_9 Amino Acid - - - 0.000001982 60.0
TLS2_k127_495023_0 Conserved TM helix - - - 0.00000000000000000000000000000000000000002529 163.0
TLS2_k127_495023_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000001742 115.0
TLS2_k127_495023_2 Acts as a magnesium transporter K06213 - - 0.00000000000000000000001251 115.0
TLS2_k127_495023_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000001564 85.0
TLS2_k127_4954943_0 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 566.0
TLS2_k127_4954943_1 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000006941 167.0
TLS2_k127_4954943_2 self proteolysis - - - 0.00000000000000000000003174 116.0
TLS2_k127_4954943_3 - - - - 0.0000000000000003034 93.0
TLS2_k127_4954943_4 general secretion pathway protein K02456,K02650,K02679 - - 0.000000000001128 78.0
TLS2_k127_4954943_5 Glucose / Sorbosone dehydrogenase - - - 0.0000000001872 74.0
TLS2_k127_4954943_6 Concanavalin A-like lectin/glucanases superfamily - - - 0.000002995 61.0
TLS2_k127_4960995_0 phosphorelay signal transduction system K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 359.0
TLS2_k127_4960995_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 312.0
TLS2_k127_4960995_2 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000002292 156.0
TLS2_k127_4960995_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000003558 138.0
TLS2_k127_4960995_5 Membrane - - - 0.0000000000000401 83.0
TLS2_k127_4960995_6 biopolymer transport protein K03559 - - 0.000000000009046 70.0
TLS2_k127_4974944_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 302.0
TLS2_k127_4974944_1 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 302.0
TLS2_k127_4982119_0 Cytochrome c - - - 0.0 1160.0
TLS2_k127_4982119_1 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1034.0
TLS2_k127_4982119_10 F5 8 type C domain - - - 0.00001638 55.0
TLS2_k127_4982119_2 Enterochelin esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 600.0
TLS2_k127_4982119_3 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 589.0
TLS2_k127_4982119_4 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 513.0
TLS2_k127_4982119_5 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 472.0
TLS2_k127_4982119_6 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 321.0
TLS2_k127_4982119_7 Glycosyl hydrolase family 62 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004484 252.0
TLS2_k127_4988603_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009859 286.0
TLS2_k127_4988603_1 RNA recognition motif - - - 0.0000000000000000000000000000000172 131.0
TLS2_k127_4998935_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 298.0
TLS2_k127_4998935_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000002856 105.0
TLS2_k127_501235_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 433.0
TLS2_k127_5018524_0 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 309.0
TLS2_k127_5018524_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000001101 181.0
TLS2_k127_5018524_2 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000014 169.0
TLS2_k127_5019512_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.006e-277 882.0
TLS2_k127_5019512_1 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 327.0
TLS2_k127_5019512_2 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000002856 217.0
TLS2_k127_5023380_0 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 537.0
TLS2_k127_5023380_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000009183 160.0
TLS2_k127_5023380_2 KilA-N - - - 0.0000000000000000000000000000000009994 132.0
TLS2_k127_5023380_3 Tetratricopeptide repeat - - - 0.000000000000000000000000003466 122.0
TLS2_k127_5023380_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000004907 84.0
TLS2_k127_5023380_5 chitinase - - - 0.000000000000009041 89.0
TLS2_k127_5023380_6 SOS response K07741,K14623 - - 0.0000003526 53.0
TLS2_k127_5039702_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 523.0
TLS2_k127_5039702_1 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 334.0
TLS2_k127_5039702_2 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000008089 186.0
TLS2_k127_5048455_0 L-methionine salvage from methylthioadenosine - - - 0.00000000000000000000000000000000000000000000000000000000002378 213.0
TLS2_k127_5048455_1 PFAM 3-dehydroquinate synthase K00096 - 1.1.1.261 0.000000000000000000000000000001024 127.0
TLS2_k127_5048455_2 cheY-homologous receiver domain - - - 0.000000000000000000002129 98.0
TLS2_k127_5048455_3 Protein of unknown function (DUF3185) - - - 0.00000000000000000114 87.0
TLS2_k127_5048455_4 - - - - 0.000000000002945 68.0
TLS2_k127_5048455_5 - - - - 0.00000001684 62.0
TLS2_k127_5048455_6 Bacterial protein of unknown function (DUF883) - - - 0.0000001424 58.0
TLS2_k127_5049815_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 394.0
TLS2_k127_5049815_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000001941 197.0
TLS2_k127_5049815_2 EamA-like transporter family - - - 0.00000000000000000001579 97.0
TLS2_k127_5058731_0 ASPIC UnbV domain protein - - - 1.878e-244 802.0
TLS2_k127_5058731_1 E-Z type HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 539.0
TLS2_k127_5058731_2 ATPase associated with K03924 - - 0.0000000000000000000000000000000000000000000002822 169.0
TLS2_k127_5058731_3 - - - - 0.0000000000000000000000002575 111.0
TLS2_k127_5058731_4 - - - - 0.0000000000000000000005846 102.0
TLS2_k127_5058731_5 cellulase activity K01187,K03466,K07017 - 3.2.1.20 0.00000000000000005331 97.0
TLS2_k127_5058731_6 FecR protein - - - 0.0000000000001191 86.0
TLS2_k127_5058731_7 domain, Protein - - - 0.0000001132 66.0
TLS2_k127_5058731_8 Alpha-1,2-mannosidase - - - 0.0000003403 64.0
TLS2_k127_5058731_9 nuclear chromosome segregation K09971 - - 0.0002697 54.0
TLS2_k127_506409_0 TIGRFAM sulfate ABC transporter, permease protein CysW, sulfate ABC transporter, permease protein K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 387.0
TLS2_k127_506409_1 sulfate ABC transporter, inner membrane subunit CysT K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 362.0
TLS2_k127_506409_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02017,K02045,K10112,K16787 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358 3.6.3.25,3.6.3.29 0.0000000000000000000000000000001849 125.0
TLS2_k127_5067227_0 efflux transmembrane transporter activity - - - 5e-323 1007.0
TLS2_k127_5067227_1 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 324.0
TLS2_k127_5067227_2 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000001437 204.0
TLS2_k127_5067227_3 sptr putative - - - 0.0009201 45.0
TLS2_k127_5070272_0 glucosamine-6-phosphate deaminase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 503.0
TLS2_k127_5070272_1 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000825 284.0
TLS2_k127_5070272_2 PFAM Phage tail sheath protein K06907 - - 0.0000000001271 64.0
TLS2_k127_5070693_0 self proteolysis - - - 0.0000000000000000000000000000000000000000000168 171.0
TLS2_k127_5070693_1 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000004011 156.0
TLS2_k127_5082955_0 ASPIC UnbV domain protein - - - 5.633e-236 759.0
TLS2_k127_5111851_0 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 469.0
TLS2_k127_5111851_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 408.0
TLS2_k127_5111851_2 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002601 222.0
TLS2_k127_5111851_3 - - - - 0.00000000000000002467 85.0
TLS2_k127_5111851_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00003666 47.0
TLS2_k127_5119573_0 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000001668 290.0
TLS2_k127_5119573_1 Belongs to the peptidase S8 family - - - 0.00000000004355 77.0
TLS2_k127_5119760_0 CotH kinase protein - - - 0.0 1199.0
TLS2_k127_5119760_1 efflux transmembrane transporter activity - - - 1.317e-210 683.0
TLS2_k127_5119760_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 442.0
TLS2_k127_5119760_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 373.0
TLS2_k127_5119760_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 296.0
TLS2_k127_5119760_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000006008 128.0
TLS2_k127_5119760_6 Protein of unknown function (DUF2492) - - - 0.00000000000000000000000002031 110.0
TLS2_k127_5119760_7 Prokaryotic N-terminal methylation motif - - - 0.0000168 51.0
TLS2_k127_5119760_8 Kelch motif - - - 0.0002336 46.0
TLS2_k127_5122324_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.915e-195 617.0
TLS2_k127_5122324_1 CHASE3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006599 540.0
TLS2_k127_5122324_10 SMART helix-turn-helix domain protein K15539 - - 0.00000000000005671 79.0
TLS2_k127_5122324_11 peptidyl-tyrosine sulfation - - - 0.000034 54.0
TLS2_k127_5122324_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 516.0
TLS2_k127_5122324_3 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 475.0
TLS2_k127_5122324_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 462.0
TLS2_k127_5122324_5 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 363.0
TLS2_k127_5122324_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000005113 218.0
TLS2_k127_5122324_7 Biotin-lipoyl like - - - 0.0000000000000000000000000001136 119.0
TLS2_k127_5122324_8 cheY-homologous receiver domain - - - 0.0000000000000000000005846 102.0
TLS2_k127_5122324_9 beta-galactosidase activity - - - 0.00000000000000002074 95.0
TLS2_k127_5130253_0 Epoxide hydrolase N terminus K01253,K21159 - 3.3.2.9 5.355e-225 702.0
TLS2_k127_5130253_1 Epoxide hydrolase N terminus K01253,K21159 - 3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 430.0
TLS2_k127_5130253_2 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000002895 212.0
TLS2_k127_5130253_3 - - - - 0.000000000000000000000000000000000000000000001506 169.0
TLS2_k127_5138404_0 WD domain, G-beta repeat - - - 0.0 1624.0
TLS2_k127_5138404_1 Protein of unknown function (DUF1501) - - - 1.924e-250 780.0
TLS2_k127_5138404_10 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005 258.0
TLS2_k127_5138404_11 TIGRFAM acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000007684 253.0
TLS2_k127_5138404_12 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000002132 221.0
TLS2_k127_5138404_13 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000002917 204.0
TLS2_k127_5138404_14 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000001133 204.0
TLS2_k127_5138404_15 NAD(P)H-dependent FMN reductase K00299 - 1.5.1.38 0.000000000000000000000000000000000000000000000005734 179.0
TLS2_k127_5138404_16 O-Antigen ligase - - - 0.0000000000000000000000000000001017 143.0
TLS2_k127_5138404_17 polysaccharide biosynthetic process - - - 0.00000001409 67.0
TLS2_k127_5138404_18 - - - - 0.0001727 48.0
TLS2_k127_5138404_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 8.073e-203 646.0
TLS2_k127_5138404_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 4.648e-200 628.0
TLS2_k127_5138404_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 590.0
TLS2_k127_5138404_5 PFAM Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 524.0
TLS2_k127_5138404_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 510.0
TLS2_k127_5138404_7 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 416.0
TLS2_k127_5138404_8 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 331.0
TLS2_k127_5138404_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 295.0
TLS2_k127_5151467_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 376.0
TLS2_k127_5151467_1 - K07039 - - 0.00000000000000000000000000000000000000000000000000001705 199.0
TLS2_k127_5151467_2 Calcineurin-like phosphoesterase K07096 - - 0.0000000000000000000000000226 120.0
TLS2_k127_5151467_3 SEC-C motif - - - 0.000000003335 57.0
TLS2_k127_5153505_0 alginic acid biosynthetic process - - - 1.519e-207 667.0
TLS2_k127_5153505_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000002425 151.0
TLS2_k127_5153505_2 Glycosyl transferases group 1 - - - 0.0000000000000002659 85.0
TLS2_k127_5161940_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 587.0
TLS2_k127_5161940_1 Beta-xylanase K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 566.0
TLS2_k127_5161940_2 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 348.0
TLS2_k127_5161940_3 Outer membrane efflux protein K18139 - - 0.0003851 45.0
TLS2_k127_5162803_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.879e-226 732.0
TLS2_k127_5162803_1 helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 552.0
TLS2_k127_5162803_10 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000000000006721 137.0
TLS2_k127_5162803_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000001343 92.0
TLS2_k127_5162803_12 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000003932 62.0
TLS2_k127_5162803_13 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000019 51.0
TLS2_k127_5162803_2 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 494.0
TLS2_k127_5162803_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 429.0
TLS2_k127_5162803_4 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 403.0
TLS2_k127_5162803_5 Transport permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 307.0
TLS2_k127_5162803_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000101 302.0
TLS2_k127_5162803_7 Transport permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 294.0
TLS2_k127_5162803_8 Belongs to the carbohydrate kinase PfkB family K00882,K00917,K16370 - 2.7.1.11,2.7.1.144,2.7.1.56 0.0000000000000000000000000000000000000000000000000000001041 207.0
TLS2_k127_5162803_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000002923 183.0
TLS2_k127_5163409_0 Cytochrome c - - - 8.719e-195 617.0
TLS2_k127_5163409_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 531.0
TLS2_k127_5163409_2 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 521.0
TLS2_k127_5163409_3 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 463.0
TLS2_k127_5163409_4 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000002015 181.0
TLS2_k127_5163409_5 arylsulfatase activity K01179,K01183 - 3.2.1.14,3.2.1.4 0.00002076 59.0
TLS2_k127_5163480_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 512.0
TLS2_k127_5163480_1 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 419.0
TLS2_k127_5163480_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000008571 188.0
TLS2_k127_5163480_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000002509 168.0
TLS2_k127_5163480_4 Response regulator receiver domain - - - 0.0000000000000000000000000000000000009554 142.0
TLS2_k127_5163480_5 DNA-templated transcription, initiation K03088 - - 0.000000000008559 74.0
TLS2_k127_517036_0 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 462.0
TLS2_k127_517036_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 291.0
TLS2_k127_517036_2 S-layer homology domain - - - 0.0000000000000000000000000000000000006529 153.0
TLS2_k127_517036_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000002042 95.0
TLS2_k127_517036_4 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000005244 93.0
TLS2_k127_517036_5 protein-(glutamine-N5) methyltransferase activity - - - 0.00000000000002363 78.0
TLS2_k127_517036_6 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000001785 68.0
TLS2_k127_517036_7 - - - - 0.000001086 57.0
TLS2_k127_517036_8 Dehydrogenase K00083 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009617,GO:0009698,GO:0009699,GO:0009808,GO:0009809,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019438,GO:0019748,GO:0043207,GO:0044237,GO:0044249,GO:0044550,GO:0045551,GO:0047681,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901576 1.1.1.195 0.0000868 53.0
TLS2_k127_5170504_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 485.0
TLS2_k127_5170504_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 287.0
TLS2_k127_5170504_2 protein conserved in bacteria K09793 - - 0.00000000000000000000000004997 115.0
TLS2_k127_5170504_3 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000003586 64.0
TLS2_k127_5183076_0 electron transfer activity - - - 2.561e-203 642.0
TLS2_k127_5183076_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 477.0
TLS2_k127_5183076_2 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 438.0
TLS2_k127_5183076_3 cellulose binding - - - 0.000000000000000000000000000000005571 138.0
TLS2_k127_5185796_0 Belongs to the glycosyl hydrolase 43 family - - - 2.593e-251 785.0
TLS2_k127_5185796_1 tRNA-splicing ligase RtcB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 587.0
TLS2_k127_5185796_3 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000002874 193.0
TLS2_k127_5185796_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000003163 183.0
TLS2_k127_5185796_5 - - - - 0.00000000000000000000000000000001367 137.0
TLS2_k127_5185796_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000884 113.0
TLS2_k127_5185796_7 - - - - 0.0000000000000000000001794 109.0
TLS2_k127_5196978_0 transport system, ATPase K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 529.0
TLS2_k127_5196978_1 Branched-chain amino acid transport system / permease component K10440,K10553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 334.0
TLS2_k127_5196978_2 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 322.0
TLS2_k127_5196978_3 protein-glutamate methylesterase K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000008252 136.0
TLS2_k127_5196978_4 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 0.0000000000008059 70.0
TLS2_k127_5197235_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 422.0
TLS2_k127_5197235_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000001347 275.0
TLS2_k127_5197235_2 Tetratricopeptide repeat - - - 0.000000000000008933 85.0
TLS2_k127_521003_0 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 342.0
TLS2_k127_521003_1 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 300.0
TLS2_k127_521003_2 Protein of unknown function (DUF2723) - - - 0.000000000000000000006418 110.0
TLS2_k127_521003_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000003338 94.0
TLS2_k127_521003_4 - - - - 0.0000000000000005283 78.0
TLS2_k127_5214781_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 432.0
TLS2_k127_5214781_1 NADH-dependent dyhydrogenase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 381.0
TLS2_k127_5214781_2 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 349.0
TLS2_k127_5214781_3 of the major facilitator superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005756 273.0
TLS2_k127_5214781_4 AAA ATPase central domain protein K03696 - - 0.00000000000000000000000000000000000000000001616 179.0
TLS2_k127_5215031_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1064.0
TLS2_k127_5215031_1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 475.0
TLS2_k127_5215031_10 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000003683 154.0
TLS2_k127_5215031_11 ABC transporter K01990 - - 0.0000000000000000000000000000000006282 140.0
TLS2_k127_5215031_12 - - - - 0.00000000000000000000000000006284 122.0
TLS2_k127_5215031_13 Winged helix DNA-binding domain - - - 0.00000000000000000000001985 103.0
TLS2_k127_5215031_14 - - - - 0.00000000000001974 83.0
TLS2_k127_5215031_15 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.00000000002669 65.0
TLS2_k127_5215031_2 sialic acid-specific 9-O-acetylesterase K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 465.0
TLS2_k127_5215031_3 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 426.0
TLS2_k127_5215031_4 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 409.0
TLS2_k127_5215031_5 Belongs to the glycosyl hydrolase 28 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 341.0
TLS2_k127_5215031_6 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 311.0
TLS2_k127_5215031_7 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001419 287.0
TLS2_k127_5215031_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000151 240.0
TLS2_k127_5215031_9 sugar phosphate isomerase involved in capsule formation K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000005144 211.0
TLS2_k127_5219409_0 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 410.0
TLS2_k127_5219409_1 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000000001896 149.0
TLS2_k127_5219409_2 SCO1/SenC K07152 - - 0.000000000000000000006683 96.0
TLS2_k127_5221218_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000002661 146.0
TLS2_k127_5221218_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000004792 99.0
TLS2_k127_5221218_2 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.0000000000000000008577 102.0
TLS2_k127_5221218_4 - - - - 0.00000007649 60.0
TLS2_k127_5228296_0 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 482.0
TLS2_k127_5228296_1 C-methyltransferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 455.0
TLS2_k127_5228296_2 RmlD substrate binding domain K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 323.0
TLS2_k127_5228296_3 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000004831 231.0
TLS2_k127_5228296_4 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000005045 135.0
TLS2_k127_5232984_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 447.0
TLS2_k127_5232984_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002278 276.0
TLS2_k127_524314_0 Alpha-2-macroglobulin family - - - 2.357e-299 930.0
TLS2_k127_5246284_0 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 414.0
TLS2_k127_5246284_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002728 271.0
TLS2_k127_5246284_2 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000001677 220.0
TLS2_k127_5246284_3 Ankyrin repeats (many copies) K10380,K15503 GO:0002262,GO:0002376,GO:0002520,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005829,GO:0005856,GO:0005886,GO:0005938,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006887,GO:0006888,GO:0006996,GO:0007010,GO:0007163,GO:0007275,GO:0008092,GO:0008093,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010638,GO:0012505,GO:0014731,GO:0015672,GO:0016020,GO:0016043,GO:0016192,GO:0016323,GO:0016528,GO:0016529,GO:0018130,GO:0019438,GO:0019899,GO:0030011,GO:0030016,GO:0030017,GO:0030018,GO:0030097,GO:0030099,GO:0030154,GO:0030218,GO:0030424,GO:0030507,GO:0030673,GO:0030674,GO:0030863,GO:0031252,GO:0031253,GO:0031256,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032589,GO:0032940,GO:0033013,GO:0033014,GO:0033036,GO:0033043,GO:0033267,GO:0034101,GO:0034613,GO:0034641,GO:0035088,GO:0035090,GO:0042383,GO:0042592,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0044237,GO:0044249,GO:0044271,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044448,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045197,GO:0045199,GO:0045202,GO:0045211,GO:0046483,GO:0046903,GO:0046907,GO:0048193,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048534,GO:0048731,GO:0048821,GO:0048856,GO:0048869,GO:0048872,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0051117,GO:0051128,GO:0051130,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051641,GO:0051649,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0060090,GO:0061245,GO:0061515,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071840,GO:0071944,GO:0072657,GO:0072659,GO:0097060,GO:0097458,GO:0098590,GO:0098771,GO:0098794,GO:0099080,GO:0099081,GO:0099512,GO:0099568,GO:0120025,GO:0120038,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1990778 - 0.000000000000000000000000000000000000000000000001479 196.0
TLS2_k127_5246284_4 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000284 196.0
TLS2_k127_526334_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 553.0
TLS2_k127_526334_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 375.0
TLS2_k127_526334_2 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000033 235.0
TLS2_k127_526334_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000004179 183.0
TLS2_k127_526334_4 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000003429 63.0
TLS2_k127_526351_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 1.024e-197 623.0
TLS2_k127_526351_1 HELICc2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 362.0
TLS2_k127_526351_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000001991 173.0
TLS2_k127_5272865_0 PhoPQ-activated pathogenicity-related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 533.0
TLS2_k127_5272865_1 and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000276 299.0
TLS2_k127_5272865_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 287.0
TLS2_k127_5272865_3 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000004644 205.0
TLS2_k127_5272865_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000001525 54.0
TLS2_k127_5272865_5 HEAT repeat - - - 0.000004301 56.0
TLS2_k127_5316972_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 303.0
TLS2_k127_5316972_1 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000007184 229.0
TLS2_k127_5316972_2 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000009055 66.0
TLS2_k127_5318224_0 FtsK/SpoIIIE family - - - 0.0 1126.0
TLS2_k127_5318224_1 PFAM Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 299.0
TLS2_k127_5318224_2 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000007584 247.0
TLS2_k127_5318224_3 - - - - 0.00000000000000000000000000000000001526 142.0
TLS2_k127_5318224_4 Proteins of 100 residues with WXG - - - 0.0000000000000000000000000002715 127.0
TLS2_k127_5318224_5 - - - - 0.0000259 51.0
TLS2_k127_5322602_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 376.0
TLS2_k127_5322602_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 371.0
TLS2_k127_5322602_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18903 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 328.0
TLS2_k127_5322602_3 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000001784 213.0
TLS2_k127_5322602_4 ECF sigma factor - - - 0.000000000000000000000000000000000000000001074 166.0
TLS2_k127_5328741_0 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 383.0
TLS2_k127_5328741_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 310.0
TLS2_k127_5328741_2 Pilus assembly protein PilX - - - 0.00000000000000000000000000006416 133.0
TLS2_k127_5328741_3 Response regulator receiver - - - 0.00000000000003687 78.0
TLS2_k127_5328741_4 Domain of Unknown Function (DUF1080) - - - 0.0000000000002239 84.0
TLS2_k127_5328741_5 Prokaryotic N-terminal methylation motif - - - 0.00009807 51.0
TLS2_k127_5336435_0 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000001409 241.0
TLS2_k127_5336435_1 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000002812 142.0
TLS2_k127_5336435_2 PFAM Nickel transport complex, NikM subunit, transmembrane K02009 - - 0.000000000000000000000000005786 120.0
TLS2_k127_5336435_3 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000001117 121.0
TLS2_k127_5351357_0 Protein-arginine kinase K19405 - 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 449.0
TLS2_k127_5351357_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 380.0
TLS2_k127_5351357_10 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000149 137.0
TLS2_k127_5351357_11 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000003498 128.0
TLS2_k127_5351357_12 - - - - 0.00000000000000000000001653 111.0
TLS2_k127_5351357_13 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000004941 98.0
TLS2_k127_5351357_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 306.0
TLS2_k127_5351357_3 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 311.0
TLS2_k127_5351357_4 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002346 248.0
TLS2_k127_5351357_5 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000004854 236.0
TLS2_k127_5351357_6 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004981 244.0
TLS2_k127_5351357_7 PFAM UvrB UvrC protein K19411 - - 0.00000000000000000000000000000000000000000000000000000001919 202.0
TLS2_k127_5351357_8 ACT domain - - - 0.00000000000000000000000000000000000000000003476 166.0
TLS2_k127_5351357_9 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000002938 143.0
TLS2_k127_5387513_0 heme-binding domain, Pirellula Verrucomicrobium type - - - 8.652e-273 867.0
TLS2_k127_5387513_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 522.0
TLS2_k127_5387513_2 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003188 269.0
TLS2_k127_5387513_3 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000004129 95.0
TLS2_k127_5387513_4 Sulfatase - - - 0.000000000003121 71.0
TLS2_k127_5390489_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 374.0
TLS2_k127_5390489_1 Serine hydrolase (FSH1) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 320.0
TLS2_k127_5390489_2 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000002858 248.0
TLS2_k127_5390489_4 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000003946 212.0
TLS2_k127_5390489_5 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000002052 149.0
TLS2_k127_5390489_6 Regulatory protein, FmdB family - - - 0.000000000000000000002318 98.0
TLS2_k127_5390489_7 Protein of unknown function (DUF2905) - - - 0.0000000000000000001297 89.0
TLS2_k127_5390489_8 Concanavalin A-like lectin/glucanases superfamily K12287 - - 0.00004325 57.0
TLS2_k127_5390489_9 Concanavalin A-like lectin/glucanases superfamily - - - 0.00009917 55.0
TLS2_k127_5396517_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 6.684e-291 920.0
TLS2_k127_5396517_1 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 504.0
TLS2_k127_5396517_10 Tetratricopeptide repeat protein - - - 0.00000001527 68.0
TLS2_k127_5396517_11 Outer membrane lipoprotein - - - 0.0001372 55.0
TLS2_k127_5396517_2 PFAM multi antimicrobial extrusion protein MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 477.0
TLS2_k127_5396517_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 445.0
TLS2_k127_5396517_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 400.0
TLS2_k127_5396517_5 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 372.0
TLS2_k127_5396517_6 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006897 332.0
TLS2_k127_5396517_7 Belongs to the heat shock protein 70 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003323 260.0
TLS2_k127_5396517_8 - - - - 0.0000000000000000001861 102.0
TLS2_k127_5396517_9 - - - - 0.000000001123 61.0
TLS2_k127_5396567_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 526.0
TLS2_k127_5396567_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 411.0
TLS2_k127_5396567_2 Hypothetical glycosyl hydrolase 6 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 421.0
TLS2_k127_5396567_3 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000002953 200.0
TLS2_k127_5396567_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000003407 165.0
TLS2_k127_5425233_0 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 426.0
TLS2_k127_5425233_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 287.0
TLS2_k127_5425233_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000003812 121.0
TLS2_k127_5432420_0 Glycolate oxidase subunit K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 556.0
TLS2_k127_5432420_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 491.0
TLS2_k127_5432420_10 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000001255 160.0
TLS2_k127_5432420_11 - - - - 0.00000000000000000000000000000004382 130.0
TLS2_k127_5432420_12 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000001076 117.0
TLS2_k127_5432420_13 domain, Protein K00703,K07082 - 2.4.1.21 0.0000000000000000000003275 105.0
TLS2_k127_5432420_14 Glycogen recognition site of AMP-activated protein kinase - - - 0.000000000003965 72.0
TLS2_k127_5432420_2 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 406.0
TLS2_k127_5432420_3 Fe-S oxidoreductase K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 348.0
TLS2_k127_5432420_4 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 295.0
TLS2_k127_5432420_5 Glycosyl transferase family 21 K03669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000842 261.0
TLS2_k127_5432420_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000006808 223.0
TLS2_k127_5432420_7 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000000000000008046 189.0
TLS2_k127_5432420_8 PFAM FAD linked oxidase domain protein K11472 - - 0.0000000000000000000000000000000000000000000006504 181.0
TLS2_k127_5432420_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000004648 177.0
TLS2_k127_5439375_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 6.764e-203 657.0
TLS2_k127_5439375_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 389.0
TLS2_k127_5439375_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000002089 204.0
TLS2_k127_5439375_3 FMN-binding domain protein - - - 0.00000005856 57.0
TLS2_k127_5453111_0 self proteolysis - - - 0.00000000000000000000000000000000000000000000005625 180.0
TLS2_k127_5453111_1 - - - - 0.000000005303 58.0
TLS2_k127_5461127_0 mannose metabolic process - - - 4.953e-275 878.0
TLS2_k127_5461127_1 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 471.0
TLS2_k127_5461127_2 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100,K03444,K08138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 431.0
TLS2_k127_5461127_3 - - - - 0.000000000000000000000000000000000000000000000000000000805 198.0
TLS2_k127_5463652_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1153.0
TLS2_k127_5463652_1 CotH kinase protein - - - 0.0000000000152 66.0
TLS2_k127_5473257_0 Aldehyde dehydrogenase family K04021 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 599.0
TLS2_k127_5473257_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 389.0
TLS2_k127_5473257_2 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 366.0
TLS2_k127_5473257_3 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 293.0
TLS2_k127_5473257_4 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.0000000000000000000000000000000000000002471 152.0
TLS2_k127_5473257_5 Domain of unknown function (DUF4252) - - - 0.000000000000000000000000000001188 129.0
TLS2_k127_5473257_6 BMC - - - 0.000000000000000000000000000001307 123.0
TLS2_k127_5473257_8 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000005684 95.0
TLS2_k127_5473257_9 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000175 94.0
TLS2_k127_550627_0 Spore coat protein CotH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 388.0
TLS2_k127_550627_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 321.0
TLS2_k127_550627_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000135 220.0
TLS2_k127_550627_3 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000003513 90.0
TLS2_k127_550627_4 Cyclic phosphodiesterase-like protein - - - 0.0001153 52.0
TLS2_k127_5506310_0 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 6.064e-204 647.0
TLS2_k127_5506310_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 509.0
TLS2_k127_5506310_10 transcriptional regulator (RpiR family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001748 253.0
TLS2_k127_5506310_11 methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000006506 231.0
TLS2_k127_5506310_12 HlyD membrane-fusion protein of T1SS K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000006627 239.0
TLS2_k127_5506310_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000002556 184.0
TLS2_k127_5506310_14 Putative adhesin - - - 0.00000000000000000000000000000000009477 150.0
TLS2_k127_5506310_15 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000005491 79.0
TLS2_k127_5506310_16 Domain of unknown function (DUF4070) - - - 0.0000001045 63.0
TLS2_k127_5506310_2 Transketolase, pyrimidine binding domain K00161,K00162,K00167,K11381 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 482.0
TLS2_k127_5506310_3 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 447.0
TLS2_k127_5506310_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 404.0
TLS2_k127_5506310_5 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 401.0
TLS2_k127_5506310_6 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 335.0
TLS2_k127_5506310_7 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 308.0
TLS2_k127_5506310_8 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 301.0
TLS2_k127_5506310_9 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006401 261.0
TLS2_k127_5520204_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 367.0
TLS2_k127_5520204_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000002702 171.0
TLS2_k127_5520204_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000001776 111.0
TLS2_k127_5520204_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000009158 64.0
TLS2_k127_5521221_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 409.0
TLS2_k127_5521221_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 327.0
TLS2_k127_552943_0 transferase activity, transferring glycosyl groups K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 509.0
TLS2_k127_552943_1 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 471.0
TLS2_k127_552943_2 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 424.0
TLS2_k127_552943_3 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 347.0
TLS2_k127_552943_4 UDP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 319.0
TLS2_k127_552943_5 Bacterial type II and III secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000009857 242.0
TLS2_k127_552943_6 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000001054 207.0
TLS2_k127_552943_7 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000756 169.0
TLS2_k127_552943_8 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000001605 91.0
TLS2_k127_5549603_0 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 508.0
TLS2_k127_5549603_1 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 327.0
TLS2_k127_5549603_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001076 235.0
TLS2_k127_5549603_3 Ferredoxin - - - 0.00000000000000000000000000000000000000000001122 168.0
TLS2_k127_555853_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 492.0
TLS2_k127_555853_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 343.0
TLS2_k127_555853_10 Biopolymer transporter TonB K03832 - - 0.0000000000000000000001642 106.0
TLS2_k127_555853_11 SnoaL-like polyketide cyclase - - - 0.00000000000000000002575 94.0
TLS2_k127_555853_12 Pkd domain containing protein - - - 0.0003134 46.0
TLS2_k127_555853_2 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 304.0
TLS2_k127_555853_3 glucosamine-6-phosphate deaminase activity K01057,K02080,K02564 GO:0003674,GO:0003824,GO:0004342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006044,GO:0006046,GO:0006047,GO:0006048,GO:0006054,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016054,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0019239,GO:0019262,GO:0019438,GO:0019752,GO:0034641,GO:0034654,GO:0042737,GO:0042802,GO:0043436,GO:0043877,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046349,GO:0046395,GO:0046483,GO:0055086,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901362,GO:1901575,GO:1901576 3.1.1.31,3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000746 248.0
TLS2_k127_555853_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000045 236.0
TLS2_k127_555853_5 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.0000000000000000000000000000000000000000000000000000000000001408 215.0
TLS2_k127_555853_6 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000008536 175.0
TLS2_k127_555853_7 biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000000008045 157.0
TLS2_k127_555853_8 Protein of unknown function (DUF3450) - - - 0.00000000000000000000000000000000001161 146.0
TLS2_k127_555853_9 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000001075 123.0
TLS2_k127_5571870_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 398.0
TLS2_k127_5571870_1 Amino acid adenylation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 407.0
TLS2_k127_5575651_0 PFAM PBS lyase HEAT domain protein - - - 0.0 1089.0
TLS2_k127_5575651_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001013 163.0
TLS2_k127_5575651_2 Acetyl xylan esterase (AXE1) - - - 0.00000000000000000000000000000009318 134.0
TLS2_k127_5579022_0 - K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 450.0
TLS2_k127_5579022_1 iron dependent repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 389.0
TLS2_k127_5579670_0 secondary active p-aminobenzoyl-glutamate transmembrane transporter activity K12942 - - 8.304e-214 675.0
TLS2_k127_5579670_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 317.0
TLS2_k127_5579670_2 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000001117 229.0
TLS2_k127_5579670_3 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000001108 186.0
TLS2_k127_5588880_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1645.0
TLS2_k127_5588880_1 PFAM HypF finger K04656 - - 1.415e-249 794.0
TLS2_k127_5588880_10 COG1668 ABC-type Na efflux pump, permease component K01992,K09696 - - 0.0000000000000000000000000000000000001716 155.0
TLS2_k127_5588880_11 AMP binding K14061 - - 0.00000000000000000000000000001321 125.0
TLS2_k127_5588880_12 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000006938 111.0
TLS2_k127_5588880_13 carbon dioxide binding K04653 - - 0.00000000000000000000003903 102.0
TLS2_k127_5588880_15 Transporter K14445 - - 0.000000000002462 69.0
TLS2_k127_5588880_16 S-layer homology domain - - - 0.000000006039 70.0
TLS2_k127_5588880_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 583.0
TLS2_k127_5588880_3 Dihydroorotate dehydrogenase K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 470.0
TLS2_k127_5588880_4 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 458.0
TLS2_k127_5588880_5 guanyl-nucleotide exchange factor activity K01183,K20276 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 394.0
TLS2_k127_5588880_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 349.0
TLS2_k127_5588880_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008142 281.0
TLS2_k127_5588880_8 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000001067 200.0
TLS2_k127_5588880_9 guanyl-nucleotide exchange factor activity K20276 - - 0.000000000000000000000000000000000000000000000000002447 210.0
TLS2_k127_5608691_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 604.0
TLS2_k127_5608691_1 FAD binding domain of DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 570.0
TLS2_k127_5608691_10 - - - - 0.0000000000000000000001505 104.0
TLS2_k127_5608691_11 MltA-interacting MipA family protein K07274 - - 0.00001205 55.0
TLS2_k127_5608691_2 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 376.0
TLS2_k127_5608691_3 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002138 308.0
TLS2_k127_5608691_4 typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000002815 270.0
TLS2_k127_5608691_5 Methane oxygenase PmoA - - - 0.000000000000000000000000000000000000000000000000000000000000000007757 237.0
TLS2_k127_5608691_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000001298 203.0
TLS2_k127_5608691_7 - - - - 0.00000000000000000000000000000000000000000000000001426 187.0
TLS2_k127_5608691_8 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000009285 135.0
TLS2_k127_5608691_9 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000003245 108.0
TLS2_k127_5609545_0 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 566.0
TLS2_k127_5609545_1 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 535.0
TLS2_k127_5609545_10 PFAM PIN domain - - - 0.0000000000000000744 85.0
TLS2_k127_5609545_11 PIN domain K07064 - - 0.0000000000003239 78.0
TLS2_k127_5609545_12 Sigma-70 region 2 - - - 0.0000003045 59.0
TLS2_k127_5609545_13 - - - - 0.0006163 49.0
TLS2_k127_5609545_2 Low molecular weight phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006772 234.0
TLS2_k127_5609545_3 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000006471 218.0
TLS2_k127_5609545_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000001686 175.0
TLS2_k127_5609545_5 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000003546 149.0
TLS2_k127_5609545_6 regulatory protein, arsR K03892,K21903 - - 0.00000000000000000000000000000004047 128.0
TLS2_k127_5609545_7 - - - - 0.000000000000000000000000000002233 126.0
TLS2_k127_5609545_8 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000003001 113.0
TLS2_k127_5609545_9 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.00000000000000000133 91.0
TLS2_k127_5613761_0 Protein of unknown function (DUF1549) - - - 1.834e-285 919.0
TLS2_k127_5613761_1 PFAM Xylose isomerase domain protein TIM barrel - - - 3.581e-212 667.0
TLS2_k127_5613761_2 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 449.0
TLS2_k127_5613761_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 389.0
TLS2_k127_5613761_4 Beta-Casp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 363.0
TLS2_k127_5613761_5 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000003404 246.0
TLS2_k127_5613761_6 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000592 177.0
TLS2_k127_5613761_7 Histidine kinase - - - 0.00000000000000000000000000000000000003735 149.0
TLS2_k127_5613761_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000001312 63.0
TLS2_k127_5613862_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 312.0
TLS2_k127_5613862_1 transferase activity, transferring glycosyl groups K21369 - 2.4.1.270 0.000000000000000000004172 108.0
TLS2_k127_5621325_0 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 536.0
TLS2_k127_5621325_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 336.0
TLS2_k127_5621325_2 typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000001164 244.0
TLS2_k127_5621325_3 Protein of unknown function (DUF2851) - - - 0.000000000000000000000000000000000000000000000000000000003343 218.0
TLS2_k127_5621325_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000003022 151.0
TLS2_k127_5621325_5 ABC-type uncharacterized transport system - - - 0.000000000000000000005969 103.0
TLS2_k127_5621569_0 Glycosyl hydrolases family 2, sugar binding domain - - - 0.0 1050.0
TLS2_k127_5621569_1 Periplasmic copper-binding protein (NosD) K01209 - 3.2.1.55 4.738e-225 727.0
TLS2_k127_5621569_2 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000000000001137 148.0
TLS2_k127_5621569_3 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.000000000000000000000000002795 130.0
TLS2_k127_5621569_4 Alpha-L-rhamnosidase - - - 0.0000000005207 62.0
TLS2_k127_5629985_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 561.0
TLS2_k127_5629985_1 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 352.0
TLS2_k127_5629985_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001104 244.0
TLS2_k127_5629985_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000001314 239.0
TLS2_k127_5637023_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K01784,K12450 - 4.2.1.46,4.2.1.76,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 414.0
TLS2_k127_5637023_1 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 301.0
TLS2_k127_5637023_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000001215 181.0
TLS2_k127_5637023_3 - - - - 0.0000000000000000007201 91.0
TLS2_k127_5637118_0 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001974 270.0
TLS2_k127_5637118_1 PFAM transposase IS66 K07484 - - 0.00000000000000000000000000000000000000000000000000000000000003009 231.0
TLS2_k127_5637118_2 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000002756 199.0
TLS2_k127_5637118_3 IS66 Orf2 like protein - - - 0.000000000000000000000000002347 115.0
TLS2_k127_5637118_4 Transposase C of IS166 homeodomain K07484 - - 0.00000000000000006506 93.0
TLS2_k127_5637118_5 Transposase K07483 - - 0.0009133 46.0
TLS2_k127_5639437_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 595.0
TLS2_k127_5639437_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 600.0
TLS2_k127_5639437_2 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 576.0
TLS2_k127_5639437_3 ResB-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 360.0
TLS2_k127_5639437_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000006287 188.0
TLS2_k127_5639437_5 - - - - 0.0000000000000000000000000000000000000008812 162.0
TLS2_k127_5639437_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000001278 85.0
TLS2_k127_5655093_0 Protein of unknown function (DUF1549) - - - 7.977e-231 736.0
TLS2_k127_5655093_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004398 263.0
TLS2_k127_5655093_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001459 215.0
TLS2_k127_5655093_3 - - - - 0.000000000000000000000000000000000000000000000000000001902 215.0
TLS2_k127_5655093_4 type I site-specific deoxyribonuclease activity K01153 - 3.1.21.3 0.000000000000000001024 91.0
TLS2_k127_5665159_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 399.0
TLS2_k127_5665159_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000009608 148.0
TLS2_k127_5665159_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000001031 143.0
TLS2_k127_5665159_3 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000004597 133.0
TLS2_k127_5665159_4 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.00000000000000004902 80.0
TLS2_k127_5665159_5 O-Antigen ligase K18814 - - 0.00000000005006 75.0
TLS2_k127_5674103_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 373.0
TLS2_k127_5674103_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534,K17686 - 3.6.3.3,3.6.3.5,3.6.3.54 0.0000000000000000000000000000000000000000000000000469 184.0
TLS2_k127_5679392_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 514.0
TLS2_k127_5679392_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 352.0
TLS2_k127_5679392_10 - - - - 0.000000000000004878 79.0
TLS2_k127_5679392_11 Sterol O-acyltransferase K00637 GO:0000062,GO:0000166,GO:0003008,GO:0003674,GO:0003824,GO:0004772,GO:0005488,GO:0005496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005903,GO:0006066,GO:0006629,GO:0006810,GO:0006869,GO:0007584,GO:0007586,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008289,GO:0008374,GO:0009605,GO:0009987,GO:0009991,GO:0010742,GO:0010876,GO:0012505,GO:0015485,GO:0015850,GO:0015918,GO:0016020,GO:0016043,GO:0016125,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0022600,GO:0022607,GO:0030154,GO:0030258,GO:0030299,GO:0030301,GO:0030554,GO:0031667,GO:0031984,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032934,GO:0033036,GO:0033218,GO:0033344,GO:0034377,GO:0034379,GO:0034381,GO:0034383,GO:0034433,GO:0034434,GO:0034435,GO:0034736,GO:0036094,GO:0042175,GO:0042221,GO:0042592,GO:0042632,GO:0043062,GO:0043167,GO:0043168,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044241,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048037,GO:0048869,GO:0048878,GO:0050662,GO:0050789,GO:0050892,GO:0050896,GO:0051179,GO:0051234,GO:0055088,GO:0055092,GO:0065003,GO:0065005,GO:0065007,GO:0065008,GO:0071702,GO:0071704,GO:0071825,GO:0071827,GO:0071840,GO:0090077,GO:0097006,GO:0097159,GO:0097367,GO:0098827,GO:0098856,GO:0098862,GO:1901265,GO:1901360,GO:1901363,GO:1901567,GO:1901615,GO:1901681,GO:1902652 2.3.1.26 0.0000002272 62.0
TLS2_k127_5679392_12 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000418 53.0
TLS2_k127_5679392_13 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.000001667 61.0
TLS2_k127_5679392_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 364.0
TLS2_k127_5679392_3 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
TLS2_k127_5679392_4 Belongs to the peptidase S41A family - - - 0.00000000000000000000000000000000000000000000000000000000000001771 233.0
TLS2_k127_5679392_5 regulation of methylation-dependent chromatin silencing K07454 - - 0.000000000000000000000000000000000000000000000000000000004638 207.0
TLS2_k127_5679392_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000002306 180.0
TLS2_k127_5679392_7 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000000000236 119.0
TLS2_k127_5679392_8 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000004263 123.0
TLS2_k127_5679392_9 recombinase activity - - - 0.000000000000000000009778 94.0
TLS2_k127_5679998_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 3.54e-207 653.0
TLS2_k127_5679998_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 455.0
TLS2_k127_5679998_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 338.0
TLS2_k127_5679998_3 Cysteine synthase K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 315.0
TLS2_k127_5679998_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000002239 256.0
TLS2_k127_5679998_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000001097 184.0
TLS2_k127_5679998_6 - - - - 0.00000000009759 68.0
TLS2_k127_5685783_0 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 328.0
TLS2_k127_5685783_1 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000002582 147.0
TLS2_k127_5685783_2 protein histidine kinase activity - - - 0.00009713 50.0
TLS2_k127_5689393_0 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 5.301e-204 650.0
TLS2_k127_5689393_1 Transcription termination factor nusG K05785 - - 0.000000000000000000000000000000000000000000002465 170.0
TLS2_k127_5689393_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000006847 176.0
TLS2_k127_5689393_3 Protein conserved in bacteria K20920 - - 0.0000000000000000000003685 109.0
TLS2_k127_5689393_4 SLBB domain - - - 0.000000000000007035 83.0
TLS2_k127_5689393_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000002637 77.0
TLS2_k127_5689393_6 Prokaryotic N-terminal methylation motif - - - 0.00000000002822 74.0
TLS2_k127_5689393_7 Lactonase, 7-bladed beta-propeller - - - 0.000000001829 69.0
TLS2_k127_570657_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 1.153e-239 748.0
TLS2_k127_570657_1 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 6.964e-196 641.0
TLS2_k127_570657_2 Membrane-bound dehydrogenase domain - - - 0.00000000000000004049 83.0
TLS2_k127_570657_3 protein conserved in cyanobacteria - - - 0.0000000000001026 79.0
TLS2_k127_570657_4 Trehalose utilisation - - - 0.00000000004492 69.0
TLS2_k127_570657_5 PIN domain - - - 0.000308 49.0
TLS2_k127_5707052_0 Domain of unknown function K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 342.0
TLS2_k127_5707052_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 332.0
TLS2_k127_5707052_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 314.0
TLS2_k127_5707052_3 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000005641 242.0
TLS2_k127_5707052_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000008347 247.0
TLS2_k127_5707052_5 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000144 204.0
TLS2_k127_5707052_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000006194 178.0
TLS2_k127_5707052_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000001343 134.0
TLS2_k127_5707052_9 Alpha-2-macroglobulin family - - - 0.000000000000000000000000001879 111.0
TLS2_k127_5707789_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0 1701.0
TLS2_k127_5707789_1 Cytochrome b/b6/petB K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 574.0
TLS2_k127_5707789_2 membrane transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 508.0
TLS2_k127_5707789_3 COG0270 Site-specific DNA methylase K00558 - 2.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 485.0
TLS2_k127_5707789_4 Rieske [2Fe-2S] domain K03886 - - 0.0000000000000000000000000000000000000000000000962 175.0
TLS2_k127_5707789_5 May nick specific sequences that contain T G mispairs resulting from m5C-deamination K07458 - - 0.00000000000000000000000001379 114.0
TLS2_k127_5708597_0 Trehalase K01194 - 3.2.1.28 1.032e-226 712.0
TLS2_k127_5708597_1 PFAM Na Pi-cotransporter K03324 - - 2.251e-198 632.0
TLS2_k127_5708597_10 Sigma-70 region 2 K03088 - - 0.00000000000000004891 85.0
TLS2_k127_5708597_11 - - - - 0.0000000001492 66.0
TLS2_k127_5708597_2 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 597.0
TLS2_k127_5708597_3 Protein of unknown function (DUF1587) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 516.0
TLS2_k127_5708597_4 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 408.0
TLS2_k127_5708597_5 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 395.0
TLS2_k127_5708597_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 376.0
TLS2_k127_5708597_7 Iron-containing alcohol dehydrogenase K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 329.0
TLS2_k127_5708597_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 319.0
TLS2_k127_5708597_9 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008162 277.0
TLS2_k127_5710426_0 Domain of unknown function (DUF4070) - - - 8.811e-215 678.0
TLS2_k127_5710426_1 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 295.0
TLS2_k127_5710426_2 membrane - - - 0.000000000000000000000000000000000000000000000000000004437 194.0
TLS2_k127_5710426_3 Cro/C1-type HTH DNA-binding domain K07727 - - 0.000000000000000000000000000001796 121.0
TLS2_k127_5711368_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 560.0
TLS2_k127_5711368_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 427.0
TLS2_k127_5711368_10 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000005079 150.0
TLS2_k127_5711368_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000002724 65.0
TLS2_k127_5711368_12 Surface antigen - - - 0.0000006433 60.0
TLS2_k127_5711368_2 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 423.0
TLS2_k127_5711368_3 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 329.0
TLS2_k127_5711368_4 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001123 285.0
TLS2_k127_5711368_5 NADH-dependent dyhydrogenase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005904 269.0
TLS2_k127_5711368_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000003041 195.0
TLS2_k127_5711368_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000029 174.0
TLS2_k127_5711368_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000009904 174.0
TLS2_k127_5711368_9 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000002176 168.0
TLS2_k127_5713594_0 5TM C-terminal transporter carbon starvation CstA - - - 0.000000000000000000000000000000000000000000000000000000000000809 212.0
TLS2_k127_5713594_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000002352 117.0
TLS2_k127_5713594_2 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000003949 123.0
TLS2_k127_5723061_0 ASPIC UnbV domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 396.0
TLS2_k127_5730967_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 364.0
TLS2_k127_5730967_1 PFAM Formylglycine-generating sulfatase enzyme K12132,K18912 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50,2.7.11.1 0.0000000000000000000000000000000000003542 152.0
TLS2_k127_5730967_2 CAAX protease self-immunity - - - 0.000000000000000000001222 105.0
TLS2_k127_5730967_3 Domain of unknown function (DUF1844) - - - 0.000000001142 65.0
TLS2_k127_5730967_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 0.000842 46.0
TLS2_k127_5732043_0 Phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 548.0
TLS2_k127_5732043_1 2-aminoethylphosphonate-pyruvate transaminase activity K01740,K03430,K05306 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 416.0
TLS2_k127_5732043_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 377.0
TLS2_k127_5732043_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000001834 243.0
TLS2_k127_5732043_4 hydrolase family 62 protein - - - 0.0007178 45.0
TLS2_k127_5732516_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 587.0
TLS2_k127_5732966_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 8.209e-256 801.0
TLS2_k127_5732966_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 507.0
TLS2_k127_5732966_2 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000002599 66.0
TLS2_k127_5740696_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 381.0
TLS2_k127_5740696_1 Methane oxygenase PmoA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 297.0
TLS2_k127_5740696_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000002917 182.0
TLS2_k127_5740696_3 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000008084 169.0
TLS2_k127_5740696_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000001423 148.0
TLS2_k127_5740696_5 PFAM oxidoreductase - - - 0.00000000000000000000000000004541 120.0
TLS2_k127_5754473_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 9.401e-229 717.0
TLS2_k127_5754473_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 537.0
TLS2_k127_5754473_2 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 507.0
TLS2_k127_5754473_3 DNA topoisomerase (ATP-hydrolyzing) K02470,K02622 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 433.0
TLS2_k127_5754473_4 Acetyltransferase (GNAT) domain K03825 - - 0.0003402 51.0
TLS2_k127_5754718_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00381 - 1.8.1.2 2.138e-228 719.0
TLS2_k127_5754718_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 459.0
TLS2_k127_5754718_2 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000901 190.0
TLS2_k127_5754718_3 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.000000000000000001448 93.0
TLS2_k127_5769767_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0 1048.0
TLS2_k127_5769767_1 oxidoreductase K00311,K00313 - 1.5.5.1 3.643e-296 924.0
TLS2_k127_5769767_10 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000007678 156.0
TLS2_k127_5769767_11 and related - - - 0.00000000000000000000000000001801 123.0
TLS2_k127_5769767_12 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0000000005422 59.0
TLS2_k127_5769767_2 RecG wedge domain K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 533.0
TLS2_k127_5769767_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 487.0
TLS2_k127_5769767_4 peptidase M42 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 351.0
TLS2_k127_5769767_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 323.0
TLS2_k127_5769767_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 310.0
TLS2_k127_5769767_7 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000001871 223.0
TLS2_k127_5769767_8 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000002248 181.0
TLS2_k127_5769767_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000007781 175.0
TLS2_k127_5788088_0 tRNA synthetases class I (W and Y) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 485.0
TLS2_k127_5788088_1 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000005218 146.0
TLS2_k127_5793698_0 polysaccharide deacetylase K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 389.0
TLS2_k127_5793698_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002623 282.0
TLS2_k127_5797084_0 Heavy-metal-associated domain K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 582.0
TLS2_k127_5797084_1 Hypothetical glycosyl hydrolase 6 - - - 0.000000000000000000000000000000000000000000000000000000000000003645 228.0
TLS2_k127_5797084_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001686 214.0
TLS2_k127_5797084_3 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000008787 212.0
TLS2_k127_5797084_4 SMART metal-dependent phosphohydrolase, HD K07037 - - 0.000000000000000000000000000000000000000000000000000000004221 218.0
TLS2_k127_5820284_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 438.0
TLS2_k127_5820284_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000005831 231.0
TLS2_k127_5820284_2 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000168 216.0
TLS2_k127_5820284_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000003904 207.0
TLS2_k127_5824403_0 - - - - 0.0 2279.0
TLS2_k127_5824403_1 - - - - 1.395e-276 876.0
TLS2_k127_5824403_2 Von Willebrand factor K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 584.0
TLS2_k127_5824403_3 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 368.0
TLS2_k127_5824403_4 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 324.0
TLS2_k127_5824403_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000001098 254.0
TLS2_k127_5824403_6 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000403 240.0
TLS2_k127_5824403_7 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000008486 203.0
TLS2_k127_5826902_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 1.326e-229 726.0
TLS2_k127_5826902_1 AI-2E family transporter - - - 1.346e-198 638.0
TLS2_k127_5826902_2 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 524.0
TLS2_k127_5826902_3 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 471.0
TLS2_k127_5826902_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 420.0
TLS2_k127_5826902_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 385.0
TLS2_k127_5826902_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006576 260.0
TLS2_k127_5826902_7 Protein of unknown function (DUF3185) - - - 0.00000000000000001052 84.0
TLS2_k127_5826902_8 phosphorelay signal transduction system - - - 0.0000107 54.0
TLS2_k127_5826902_9 helix_turn_helix, Lux Regulon - - - 0.0001765 46.0
TLS2_k127_5852244_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 4.103e-217 698.0
TLS2_k127_5852244_1 AcrB/AcrD/AcrF family - - - 1.842e-197 621.0
TLS2_k127_5852244_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 393.0
TLS2_k127_5852244_3 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000000000000000000007526 204.0
TLS2_k127_5852244_4 FAD dependent oxidoreductase - - - 0.0000184 51.0
TLS2_k127_5852244_5 FAD dependent oxidoreductase - - - 0.0000272 47.0
TLS2_k127_5875408_0 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 586.0
TLS2_k127_5875408_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 402.0
TLS2_k127_5875674_0 response to heat K03696 - - 0.0 1013.0
TLS2_k127_5875674_1 PFAM Acetyl-CoA hydrolase transferase - - - 4.592e-256 803.0
TLS2_k127_5875674_10 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000001863 163.0
TLS2_k127_5875674_11 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000012 107.0
TLS2_k127_5875674_12 Putative prokaryotic signal transducing protein - - - 0.0002187 46.0
TLS2_k127_5875674_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 3.162e-250 792.0
TLS2_k127_5875674_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 559.0
TLS2_k127_5875674_4 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 500.0
TLS2_k127_5875674_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 331.0
TLS2_k127_5875674_6 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 310.0
TLS2_k127_5875674_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003064 272.0
TLS2_k127_5875674_8 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008526 258.0
TLS2_k127_5875674_9 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000002926 236.0
TLS2_k127_5884800_0 AIR synthase related protein, C-terminal domain K01952 - 6.3.5.3 8.159e-250 792.0
TLS2_k127_5884800_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 576.0
TLS2_k127_5884800_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 306.0
TLS2_k127_5884800_3 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002711 254.0
TLS2_k127_5884800_4 protein flavinylation K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000001235 240.0
TLS2_k127_5884800_5 PFAM UvrB UvrC protein K08999,K19411 - - 0.0000000000000000000000000000000000000000000000000000002247 203.0
TLS2_k127_5884800_6 Glycosyl transferase - - - 0.00000000000000000000000000000000000000003414 163.0
TLS2_k127_5884800_7 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000008522 111.0
TLS2_k127_5884800_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000512 90.0
TLS2_k127_5893870_0 PFAM transposase IS66 K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 376.0
TLS2_k127_5893870_1 PFAM IS66 Orf2 family protein K07484 - - 0.0000000000000000000000000005942 122.0
TLS2_k127_5896398_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1143.0
TLS2_k127_5896398_1 domain protein K02674,K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 672.0
TLS2_k127_5896398_10 general secretion pathway protein - - - 0.000000000001771 79.0
TLS2_k127_5896398_11 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.00000004885 67.0
TLS2_k127_5896398_12 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000009843 64.0
TLS2_k127_5896398_13 Sulfatase - - - 0.000005305 60.0
TLS2_k127_5896398_14 PFAM YD repeat-containing protein - - - 0.00001966 60.0
TLS2_k127_5896398_15 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.0005571 52.0
TLS2_k127_5896398_2 Bile acid sodium symporter K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 372.0
TLS2_k127_5896398_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002037 250.0
TLS2_k127_5896398_4 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000001609 221.0
TLS2_k127_5896398_5 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000002225 224.0
TLS2_k127_5896398_6 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000001926 196.0
TLS2_k127_5896398_7 COG2931 RTX toxins and related Ca2 -binding proteins K01406 - 3.4.24.40 0.000000000000000000000000000000000000000000000002095 199.0
TLS2_k127_5896398_8 Cobalt-zinc-cadmium resistance protein K15725 - - 0.0000000000000000000000000007327 128.0
TLS2_k127_5896398_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000001499 117.0
TLS2_k127_5903878_0 - - - - 0.0 1100.0
TLS2_k127_5903878_1 Insecticidal toxin complex - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 492.0
TLS2_k127_5903878_2 - - - - 0.0000000000000000000000000000003817 137.0
TLS2_k127_5903878_3 PA14 - - - 0.0000000000000000000000000004874 135.0
TLS2_k127_5915262_0 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 1.669e-245 769.0
TLS2_k127_5915262_1 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 338.0
TLS2_k127_5915262_2 cephalosporin-C deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 288.0
TLS2_k127_5915262_3 Putative esterase K07214 - - 0.0000001239 57.0
TLS2_k127_5925830_0 ThiC-associated domain K03147 - 4.1.99.17 3.023e-261 814.0
TLS2_k127_5925830_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 502.0
TLS2_k127_5925830_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 478.0
TLS2_k127_5925830_3 protein with protein kinase and helix-hairpin-helix DNA-binding - - - 0.000000000000000000000000000000000000004821 163.0
TLS2_k127_5925830_4 Tetratricopeptide repeat - - - 0.000004343 58.0
TLS2_k127_5925830_5 8-amino-7-oxononanoate synthase activity K00639,K00652,K10915 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.3.1.29,2.3.1.47 0.000007896 51.0
TLS2_k127_5930339_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 451.0
TLS2_k127_5930339_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005691 239.0
TLS2_k127_5930339_2 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000006184 216.0
TLS2_k127_5930339_3 - - - - 0.000000000000009297 77.0
TLS2_k127_5931980_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 1.414e-241 760.0
TLS2_k127_5931980_1 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 610.0
TLS2_k127_5931980_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000007644 119.0
TLS2_k127_5931980_11 type II secretion system protein K02653 - - 0.000000000000000000000005156 114.0
TLS2_k127_5931980_12 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000002191 100.0
TLS2_k127_5931980_13 Beta-lactamase - - - 0.00000000000000000001843 93.0
TLS2_k127_5931980_15 Beta-lactamase - - - 0.00000000002629 70.0
TLS2_k127_5931980_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 421.0
TLS2_k127_5931980_3 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 354.0
TLS2_k127_5931980_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 356.0
TLS2_k127_5931980_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 311.0
TLS2_k127_5931980_6 Permease - - - 0.0000000000000000000000000000000000000000000001719 180.0
TLS2_k127_5931980_7 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000000000000000003007 149.0
TLS2_k127_5931980_8 Thioredoxin K03671 - - 0.0000000000000000000000000000000000008589 148.0
TLS2_k127_5931980_9 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000004168 120.0
TLS2_k127_5936119_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 296.0
TLS2_k127_5936119_1 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004769 265.0
TLS2_k127_5936860_0 Indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 2.019e-223 704.0
TLS2_k127_5936860_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 5.825e-209 670.0
TLS2_k127_5936860_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.34e-207 653.0
TLS2_k127_5936860_3 Acetyl xylan esterase (AXE1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 519.0
TLS2_k127_5936860_4 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 349.0
TLS2_k127_5936860_5 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000001412 212.0
TLS2_k127_5936860_6 PFAM Amino acid-binding ACT - - - 0.00000000000000000000000000000000000000003947 162.0
TLS2_k127_5936860_7 thiolester hydrolase activity K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.0000000000000000000000000000000000000001754 155.0
TLS2_k127_5936860_8 - - - - 0.0000004215 55.0
TLS2_k127_5936860_9 Trehalose utilisation - - - 0.0000004941 56.0
TLS2_k127_5941329_0 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005339 275.0
TLS2_k127_5941329_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000008346 207.0
TLS2_k127_5941329_2 KR domain - - - 0.00000000000000000000000000000000000004538 144.0
TLS2_k127_5941990_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 595.0
TLS2_k127_5941990_1 TIGRFAM SagB-type dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 512.0
TLS2_k127_5941990_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 452.0
TLS2_k127_5941990_3 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 409.0
TLS2_k127_5941990_4 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 353.0
TLS2_k127_5941990_5 Sodium/calcium exchanger protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003097 276.0
TLS2_k127_5941990_6 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000000000000000006921 206.0
TLS2_k127_5941990_7 - - - - 0.000000000000000000000000000000000000000000000000000003509 196.0
TLS2_k127_5941990_8 Response regulator receiver domain - - - 0.000000000000000000001141 99.0
TLS2_k127_5941990_9 myo-inosose-2 dehydratase activity - - - 0.00000028 62.0
TLS2_k127_5979473_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 520.0
TLS2_k127_5979473_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000001344 69.0
TLS2_k127_5985250_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.997e-219 694.0
TLS2_k127_5985250_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 539.0
TLS2_k127_5985250_10 Domains in Na-Ca exchangers and integrin-beta4 - - - 0.00001962 51.0
TLS2_k127_5985250_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 454.0
TLS2_k127_5985250_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 322.0
TLS2_k127_5985250_4 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 296.0
TLS2_k127_5985250_5 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002218 265.0
TLS2_k127_5985250_6 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000827 181.0
TLS2_k127_5985250_7 - - - - 0.0000000000000006209 81.0
TLS2_k127_5985250_8 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000003062 70.0
TLS2_k127_5985250_9 - - - - 0.00000000007075 75.0
TLS2_k127_5990362_0 COG1680 Beta-lactamase class C and other penicillin binding - - - 2.302e-266 837.0
TLS2_k127_5990362_1 PFAM Ketopantoate reductase ApbA PanE, C-terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 437.0
TLS2_k127_5990362_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 372.0
TLS2_k127_5990362_3 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 332.0
TLS2_k127_5990362_4 gluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000001448 225.0
TLS2_k127_5990362_5 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000000000002273 166.0
TLS2_k127_5990362_6 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000001155 154.0
TLS2_k127_5990362_7 PFAM GCN5-related N-acetyltransferase K03830 - - 0.000000000000000000000000000000000235 137.0
TLS2_k127_5990362_8 NmrA-like family K00091 - 1.1.1.219 0.0004132 43.0
TLS2_k127_5990930_0 Group II intron maturase-specific domain protein K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 436.0
TLS2_k127_5990930_1 transposase activity K07493 - - 0.00000000000000000000000000000000000000000000000000000000000007942 222.0
TLS2_k127_5990930_2 Sulfatase-modifying factor enzyme 1 K02396,K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000005082 213.0
TLS2_k127_5990930_3 MULE transposase domain - - - 0.000000000000000000000000000000000000000000000000004222 190.0
TLS2_k127_5990930_4 transposase activity - - - 0.000006057 49.0
TLS2_k127_5996954_0 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 556.0
TLS2_k127_5996954_1 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 377.0
TLS2_k127_5996954_2 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 327.0
TLS2_k127_5996954_3 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 310.0
TLS2_k127_5996954_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 299.0
TLS2_k127_5996954_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000748 273.0
TLS2_k127_5996954_6 PFAM Protein kinase domain - - - 0.00000000000000000000000000004806 126.0
TLS2_k127_5996954_7 protein histidine kinase activity K13924 - 2.1.1.80,3.1.1.61 0.00000000000000001385 98.0
TLS2_k127_5996954_8 ATPase family associated with various cellular activities (AAA) K07478 - - 0.00000000006757 65.0
TLS2_k127_5996954_9 COG2165 Type II secretory pathway, pseudopilin PulG K02456 - - 0.00001312 55.0
TLS2_k127_6005000_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 546.0
TLS2_k127_6005000_1 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 338.0
TLS2_k127_6005000_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 310.0
TLS2_k127_6005000_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000009919 153.0
TLS2_k127_6005000_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000004975 105.0
TLS2_k127_6005000_5 VTC domain - - - 0.0000000000000000006369 97.0
TLS2_k127_6005000_6 Domain of unknown function (DUF4956) - - - 0.000000000000000003025 93.0
TLS2_k127_6005000_7 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000001656 66.0
TLS2_k127_6013382_0 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 6.543e-196 625.0
TLS2_k127_6013382_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 310.0
TLS2_k127_6017503_0 Concanavalin A-like lectin/glucanases superfamily - - - 4.409e-298 938.0
TLS2_k127_6017503_1 Protein of unknown function (DUF1501) - - - 1.506e-228 717.0
TLS2_k127_6017503_2 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 359.0
TLS2_k127_6017503_3 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 310.0
TLS2_k127_6017503_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000001195 56.0
TLS2_k127_6018976_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001133 275.0
TLS2_k127_6018976_1 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000002515 226.0
TLS2_k127_6018976_2 PAP2 superfamily - - - 0.000000000000000000000002068 112.0
TLS2_k127_6036894_0 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000001206 170.0
TLS2_k127_6036894_1 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000001873 119.0
TLS2_k127_6036894_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000004087 111.0
TLS2_k127_6036894_3 - - - - 0.0000000000000001641 83.0
TLS2_k127_6036894_4 Plasmid stabilization system - - - 0.00000000000001853 73.0
TLS2_k127_6036894_5 Protein of unknown function (DUF2442) - - - 0.00000000003757 67.0
TLS2_k127_6036894_6 Plasmid stabilization system - - - 0.0000007645 51.0
TLS2_k127_6037786_0 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 380.0
TLS2_k127_6037786_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000001348 158.0
TLS2_k127_6037786_2 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.000000000000000000000000000000006312 138.0
TLS2_k127_6037786_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000001365 95.0
TLS2_k127_6037786_4 RNA polymerase activity K03060 - 2.7.7.6 0.000003721 52.0
TLS2_k127_6041659_0 C4-dicarboxylate anaerobic carrier - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 477.0
TLS2_k127_6041659_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 452.0
TLS2_k127_6041659_10 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000001211 161.0
TLS2_k127_6041659_11 - - - - 0.0000000000000000000000000000002882 124.0
TLS2_k127_6041659_12 Protein of unknown function (DUF1559) - - - 0.0000000000000000000000000009748 128.0
TLS2_k127_6041659_13 Glycosyl hydrolases family 32 K01212,K03332 - 3.2.1.65,3.2.1.80 0.000000000000000000000000001466 123.0
TLS2_k127_6041659_14 Sigma-70, region 4 K03088 - - 0.000000000000000000000000006442 116.0
TLS2_k127_6041659_15 Glycosyl hydrolases family 32 K01212,K03332 - 3.2.1.65,3.2.1.80 0.00000000000000001736 89.0
TLS2_k127_6041659_16 alpha-L-arabinofuranosidase - - - 0.00000000000006045 85.0
TLS2_k127_6041659_18 beta-propeller repeat - - - 0.000000007445 66.0
TLS2_k127_6041659_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 381.0
TLS2_k127_6041659_3 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 363.0
TLS2_k127_6041659_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 325.0
TLS2_k127_6041659_5 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 318.0
TLS2_k127_6041659_6 Peptidase family C69 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001456 288.0
TLS2_k127_6041659_7 - - - - 0.00000000000000000000000000000000000000000000000000004113 207.0
TLS2_k127_6041659_8 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000007584 184.0
TLS2_k127_6041659_9 methyltransferase - - - 0.000000000000000000000000000000000000000000000008452 181.0
TLS2_k127_604339_0 PFAM Xylose isomerase K01820 - 5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 582.0
TLS2_k127_604339_1 Belongs to the purine-cytosine permease (2.A.39) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 570.0
TLS2_k127_604339_10 TM2 domain - - - 0.000000000000000001282 91.0
TLS2_k127_604339_2 PFAM SMP-30 Gluconolaconase K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 473.0
TLS2_k127_604339_3 gluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 447.0
TLS2_k127_604339_4 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 283.0
TLS2_k127_604339_5 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001101 244.0
TLS2_k127_604339_6 2-epimerase K16213 - 5.1.3.11 0.0000000000000000000000000000000000000000000000000000000000003176 228.0
TLS2_k127_604339_7 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000005262 137.0
TLS2_k127_604339_8 aggregation factor core protein MAFp3, isoform C - - - 0.00000000000000000000000000000002611 147.0
TLS2_k127_604339_9 cyclic nucleotide binding K10914 - - 0.000000000000000000000076 108.0
TLS2_k127_6052048_0 COG1012 NAD-dependent aldehyde dehydrogenases K19588 - 1.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 474.0
TLS2_k127_6052048_1 fumarylacetoacetate (FAA) hydrolase K14259 - 4.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003773 279.0
TLS2_k127_6052048_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000005509 254.0
TLS2_k127_6052048_3 ASPIC UnbV domain protein - - - 0.0000002746 53.0
TLS2_k127_6068987_0 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 377.0
TLS2_k127_6068987_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 330.0
TLS2_k127_6068987_2 Aldo Keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000003035 233.0
TLS2_k127_6068987_3 PFAM Spore coat protein CotH - - - 0.00000003341 56.0
TLS2_k127_6068987_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000001435 54.0
TLS2_k127_6078347_0 beta-N-acetylhexosaminidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 383.0
TLS2_k127_6078347_1 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000003181 217.0
TLS2_k127_6078347_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000001717 194.0
TLS2_k127_6078347_3 Zn-dependent protease with chaperone function - - - 0.0000004717 58.0
TLS2_k127_6094515_0 asparagine synthase K01953 - 6.3.5.4 2.076e-215 675.0
TLS2_k127_6094515_1 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000001691 185.0
TLS2_k127_611177_0 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 605.0
TLS2_k127_611177_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 497.0
TLS2_k127_611177_2 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 396.0
TLS2_k127_611177_3 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 332.0
TLS2_k127_611177_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000405 166.0
TLS2_k127_6118610_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 348.0
TLS2_k127_6118610_1 - - - - 0.000000000000000000000000000000000000000000000000005778 187.0
TLS2_k127_6118610_2 Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.00000000000000000002043 104.0
TLS2_k127_6118610_3 - - - - 0.00000000000000005824 83.0
TLS2_k127_6122945_0 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 351.0
TLS2_k127_6122945_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000185 203.0
TLS2_k127_6122945_2 PFAM D-galactarate dehydratase Altronate hydrolase K01685 - 4.2.1.7 0.000000000009201 65.0
TLS2_k127_6122945_3 Periplasmic binding protein domain - - - 0.0000000001758 66.0
TLS2_k127_6123851_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.294e-222 706.0
TLS2_k127_6123851_1 COG3119 Arylsulfatase A and related enzymes K01136 - 3.1.6.13 0.0000000000000000000000000002024 116.0
TLS2_k127_6123851_2 Cytochrome c - - - 0.0000001875 63.0
TLS2_k127_6133307_0 Glycosyltransferase family 9 (heptosyltransferase) - - - 4.637e-214 682.0
TLS2_k127_6133307_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 385.0
TLS2_k127_6133307_10 - - - - 0.00000000000000000000000000000159 130.0
TLS2_k127_6133307_11 - - - - 0.0000000000000000000000000002983 132.0
TLS2_k127_6133307_12 PFAM response regulator receiver - - - 0.0000000000000000002405 92.0
TLS2_k127_6133307_13 DNA integration K07497 - - 0.0000000000000000003192 95.0
TLS2_k127_6133307_14 - - - - 0.0000000000000001107 86.0
TLS2_k127_6133307_15 RES - - - 0.00000000003493 72.0
TLS2_k127_6133307_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 327.0
TLS2_k127_6133307_3 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009161 310.0
TLS2_k127_6133307_4 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000004437 245.0
TLS2_k127_6133307_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001966 243.0
TLS2_k127_6133307_6 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000111 215.0
TLS2_k127_6133307_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000008645 203.0
TLS2_k127_6133307_8 AAA-like domain - - - 0.000000000000000000000000000000000000000001265 181.0
TLS2_k127_6133307_9 PFAM response regulator receiver - - - 0.0000000000000000000000000000009519 126.0
TLS2_k127_6154768_0 alcohol dehydrogenase K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 472.0
TLS2_k127_6154768_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 362.0
TLS2_k127_6154768_10 Cell division protein FtsQ K03589 - - 0.000001132 60.0
TLS2_k127_6154768_11 ribonuclease activity - - - 0.000006884 49.0
TLS2_k127_6154768_2 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 297.0
TLS2_k127_6154768_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004663 278.0
TLS2_k127_6154768_4 Mur ligase family, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003525 270.0
TLS2_k127_6154768_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000002551 234.0
TLS2_k127_6154768_6 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000000000006647 214.0
TLS2_k127_6154768_7 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.00000000000000000000000000000000005529 141.0
TLS2_k127_6154768_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000005596 103.0
TLS2_k127_6154768_9 anaphase-promoting complex binding - - - 0.000000001409 60.0
TLS2_k127_6158948_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 1.749e-197 625.0
TLS2_k127_6158948_1 PFAM Binding-protein-dependent transport systems inner membrane component K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 423.0
TLS2_k127_6158948_2 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 404.0
TLS2_k127_6158948_3 ABC transporter K02049,K15578,K15579 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 386.0
TLS2_k127_6158948_4 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 301.0
TLS2_k127_6158948_5 Transcriptional regulator K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003132 246.0
TLS2_k127_6158948_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K07307 - - 0.0000006677 52.0
TLS2_k127_616626_0 ATP-dependent peptidase activity K01338 - 3.4.21.53 6.619e-268 846.0
TLS2_k127_616626_1 ATPase activity K06027 - 3.6.4.6 1.747e-237 743.0
TLS2_k127_616626_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000001219 237.0
TLS2_k127_616626_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000189 87.0
TLS2_k127_616626_4 Outer membrane lipoprotein-sorting protein - - - 0.00000000234 68.0
TLS2_k127_6208098_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 2.215e-213 670.0
TLS2_k127_6208098_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 2.26e-196 622.0
TLS2_k127_6208098_2 and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 529.0
TLS2_k127_6208098_3 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000000000000001248 165.0
TLS2_k127_6208098_4 beta-galactosidase activity - - - 0.00000000000000995 78.0
TLS2_k127_6230381_0 transmembrane signaling receptor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 389.0
TLS2_k127_6238534_0 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008014 276.0
TLS2_k127_6238534_1 - - - - 0.00000000000000000000000000000000000000000014 170.0
TLS2_k127_6238534_2 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.0000000000000000000000000000000000001908 145.0
TLS2_k127_6238534_3 Citrate lyase, alpha subunit (CitF) - - - 0.000000000000000000000000007462 120.0
TLS2_k127_6238534_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000004642 66.0
TLS2_k127_6242531_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.747e-251 794.0
TLS2_k127_6242531_1 Elongator protein 3, MiaB family, Radical SAM K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 404.0
TLS2_k127_6242531_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000001069 205.0
TLS2_k127_6242531_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000004365 141.0
TLS2_k127_624258_0 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 4.098e-198 633.0
TLS2_k127_624258_1 Bacterial type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 394.0
TLS2_k127_624258_2 - - - - 0.0000000000000000000000000000000000000002868 169.0
TLS2_k127_6246982_0 Encoded by - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 378.0
TLS2_k127_6246982_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004608 282.0
TLS2_k127_6246982_2 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000001366 224.0
TLS2_k127_6246982_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000005472 197.0
TLS2_k127_6246982_4 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000009123 168.0
TLS2_k127_6246982_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000001016 154.0
TLS2_k127_6246982_6 Methanol-cobalamin methyltransferase B subunit K04480 - 2.1.1.90 0.000000000000000000000000000000002216 134.0
TLS2_k127_6246982_7 Transposase IS116 IS110 IS902 - - - 0.000000000000000683 81.0
TLS2_k127_6259962_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 429.0
TLS2_k127_6259962_1 Domain of unknown function (4846) - - - 0.000000000000000000000000000000000000000000000000000000009736 209.0
TLS2_k127_6259962_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000002472 190.0
TLS2_k127_6262638_0 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 1.008e-220 720.0
TLS2_k127_6262638_1 mandelate racemase muconate lactonizing K08323 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 421.0
TLS2_k127_6262638_2 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 353.0
TLS2_k127_6272184_0 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 626.0
TLS2_k127_6272184_1 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 578.0
TLS2_k127_6272184_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 467.0
TLS2_k127_6272184_3 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 315.0
TLS2_k127_6272184_4 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000003376 193.0
TLS2_k127_6272184_5 glycine-rich protein - - - 0.00006562 55.0
TLS2_k127_6272184_6 domain protein K17624 - 3.2.1.97 0.0003295 52.0
TLS2_k127_6277059_0 Aldehyde dehydrogenase family - - - 1.136e-229 719.0
TLS2_k127_6277059_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 372.0
TLS2_k127_6277059_2 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000000002197 158.0
TLS2_k127_6277059_3 mevalonate kinase activity - - - 0.000000308 53.0
TLS2_k127_6280247_0 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 573.0
TLS2_k127_6280247_1 ABC transporter K02049,K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 329.0
TLS2_k127_6280247_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 285.0
TLS2_k127_6280247_3 NmrA-like family - - - 0.00000000000000000000000000000000000000000000007619 180.0
TLS2_k127_6280247_4 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000001226 138.0
TLS2_k127_6280247_5 methylamine metabolic process K15977 - - 0.0000102 49.0
TLS2_k127_6281478_0 Protein of unknown function (DUF1501) - - - 3.55e-200 628.0
TLS2_k127_6281478_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 1.217e-197 640.0
TLS2_k127_6346221_0 Immunoglobulin I-set domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 390.0
TLS2_k127_6346221_1 PQQ enzyme repeat - - - 0.0000000000000000000000000000000002195 132.0
TLS2_k127_6381135_0 efflux transmembrane transporter activity - - - 3.404e-214 692.0
TLS2_k127_6381135_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 594.0
TLS2_k127_6381135_10 Ankyrin repeats (many copies) - - - 0.000000000001271 72.0
TLS2_k127_6381135_11 Sulfatase-modifying factor enzyme 1 - - - 0.000000002874 64.0
TLS2_k127_6381135_12 MacB-like periplasmic core domain - - - 0.00000009578 55.0
TLS2_k127_6381135_13 FtsX-like permease family - - - 0.0001669 51.0
TLS2_k127_6381135_14 - - - - 0.0009956 51.0
TLS2_k127_6381135_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 408.0
TLS2_k127_6381135_3 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000001626 218.0
TLS2_k127_6381135_4 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000004808 196.0
TLS2_k127_6381135_5 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000002811 136.0
TLS2_k127_6381135_6 Glyoxalase-like domain - - - 0.0000000000000000000000000006561 117.0
TLS2_k127_6381135_7 MacB-like periplasmic core domain - - - 0.000000000000000000000316 104.0
TLS2_k127_6381135_8 lactoylglutathione lyase activity - - - 0.000000000000000000001743 96.0
TLS2_k127_6381135_9 Beta-lactamase K01286 - 3.4.16.4 0.000000000001261 72.0
TLS2_k127_6426478_0 AbgT putative transporter family K12942 - - 6.971e-206 654.0
TLS2_k127_6426478_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 414.0
TLS2_k127_6426478_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 364.0
TLS2_k127_6426478_3 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003696 238.0
TLS2_k127_6426478_5 KR domain K13370 GO:0000166,GO:0003674,GO:0003824,GO:0003857,GO:0004303,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006694,GO:0006703,GO:0008150,GO:0008152,GO:0008202,GO:0008209,GO:0008210,GO:0008610,GO:0009058,GO:0009987,GO:0010817,GO:0016020,GO:0016043,GO:0016053,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0031967,GO:0031974,GO:0031975,GO:0032787,GO:0033764,GO:0034754,GO:0036094,GO:0042445,GO:0042446,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0047025,GO:0047035,GO:0048037,GO:0050662,GO:0051259,GO:0051262,GO:0051287,GO:0051290,GO:0051291,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070404,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.1.1.239,1.1.1.62 0.0000001105 55.0
TLS2_k127_6452313_0 IS66 C-terminal element K07484 - - 4.524e-250 782.0
TLS2_k127_6452313_1 IS66 Orf2 like protein - - - 0.000000000000000000000000000000000000000000000000000003701 193.0
TLS2_k127_6452313_2 Transposase K07483 - - 0.0000000000000000002597 93.0
TLS2_k127_6454490_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 389.0
TLS2_k127_6454490_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 293.0
TLS2_k127_6484010_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.819e-304 942.0
TLS2_k127_6484010_1 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009517 267.0
TLS2_k127_6484010_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000001134 162.0
TLS2_k127_6484010_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000001869 139.0
TLS2_k127_6484010_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000001717 133.0
TLS2_k127_6488269_0 Transposase K07491 - - 0.00000000000000000000000000000000000000000000000000000000005323 213.0
TLS2_k127_6488269_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000001186 80.0
TLS2_k127_6488269_2 domain protein - - - 0.0003215 45.0
TLS2_k127_6488272_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 8.802e-255 809.0
TLS2_k127_6488272_1 Cytochrome c - - - 1.651e-235 763.0
TLS2_k127_6488272_2 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 546.0
TLS2_k127_6488272_3 Protein of unknown function (DUF2959) - - - 0.00000000000000002124 83.0
TLS2_k127_6488272_4 CHRD domain - - - 0.0000000000001419 78.0
TLS2_k127_6490529_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 364.0
TLS2_k127_6490529_1 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000005707 204.0
TLS2_k127_6490529_2 Y_Y_Y domain - - - 0.00000000000000000000000004159 117.0
TLS2_k127_6490529_3 cheY-homologous receiver domain - - - 0.000000000000000000001963 98.0
TLS2_k127_6511376_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 518.0
TLS2_k127_6511376_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 499.0
TLS2_k127_6511376_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000006017 133.0
TLS2_k127_6511376_11 Bacterial type II and III secretion system protein K02453 - - 0.000000000000000000000000000002681 137.0
TLS2_k127_6511376_12 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000002067 128.0
TLS2_k127_6511376_13 Pilus assembly protein K02662 - - 0.000000000000003318 87.0
TLS2_k127_6511376_14 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000006724 56.0
TLS2_k127_6511376_2 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 492.0
TLS2_k127_6511376_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 429.0
TLS2_k127_6511376_4 Zn-dependent metallo-hydrolase RNA specificity domain K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 347.0
TLS2_k127_6511376_5 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 315.0
TLS2_k127_6511376_6 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000006709 262.0
TLS2_k127_6511376_7 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005517 248.0
TLS2_k127_6511376_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000002046 231.0
TLS2_k127_6511376_9 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000002691 160.0
TLS2_k127_6547709_0 Citrate transporter - - - 5.014e-244 766.0
TLS2_k127_6547709_1 MacB-like periplasmic core domain - - - 1.747e-197 646.0
TLS2_k127_6547709_10 Chromate resistance exported protein - - - 0.00000000000000000000000000003941 122.0
TLS2_k127_6547709_11 Amino acid permease K03294 - - 0.000000000000000000000000003906 119.0
TLS2_k127_6547709_12 DDE_Tnp_1-associated - - - 0.00000000000000000000001133 105.0
TLS2_k127_6547709_14 amino acid K03294 - - 0.0000000004876 68.0
TLS2_k127_6547709_15 Cysteine-rich secretory protein family - - - 0.000000001304 72.0
TLS2_k127_6547709_16 Pectate lyase K01728 - 4.2.2.2 0.00000001312 62.0
TLS2_k127_6547709_17 Citrate transporter - - - 0.000002636 53.0
TLS2_k127_6547709_18 Belongs to the 'phage' integrase family - - - 0.000005543 51.0
TLS2_k127_6547709_19 GTA TIM-barrel-like domain - - - 0.000007064 58.0
TLS2_k127_6547709_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 503.0
TLS2_k127_6547709_20 Forkhead associated domain - - - 0.00003034 49.0
TLS2_k127_6547709_3 membrane K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 466.0
TLS2_k127_6547709_4 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 409.0
TLS2_k127_6547709_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 382.0
TLS2_k127_6547709_6 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 357.0
TLS2_k127_6547709_7 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 336.0
TLS2_k127_6547709_8 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000003814 173.0
TLS2_k127_6547709_9 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000008812 161.0
TLS2_k127_6549833_0 secreted protein-putative xanthan lyase related - - - 8.993e-293 905.0
TLS2_k127_6549833_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 357.0
TLS2_k127_6549833_2 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000006642 223.0
TLS2_k127_6549833_3 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000001324 219.0
TLS2_k127_6549833_4 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000000001183 125.0
TLS2_k127_6549833_5 Protein of unknown function (DUF4230) - - - 0.0000000000002179 78.0
TLS2_k127_6549833_6 domain, Protein - - - 0.0000004342 58.0
TLS2_k127_6556918_0 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 524.0
TLS2_k127_6556918_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 324.0
TLS2_k127_6556918_2 cellulose binding - - - 0.0000000000000000000000000000000000009731 162.0
TLS2_k127_6556918_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000003533 143.0
TLS2_k127_6556918_4 arginyl-trna synthetase - - - 0.00000000000000003206 98.0
TLS2_k127_6566898_0 domain protein K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 311.0
TLS2_k127_6566898_1 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000664 291.0
TLS2_k127_6566898_2 Haloacid dehalogenase-like hydrolase - - - 0.0008381 44.0
TLS2_k127_6575640_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.142e-221 696.0
TLS2_k127_6575640_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03471 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002487 280.0
TLS2_k127_6575640_2 Adenine glycosylase K03574,K03575 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000003889 206.0
TLS2_k127_6590732_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 566.0
TLS2_k127_6590732_10 PFAM intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 303.0
TLS2_k127_6590732_11 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 293.0
TLS2_k127_6590732_12 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008633 284.0
TLS2_k127_6590732_13 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007403 271.0
TLS2_k127_6590732_14 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002892 262.0
TLS2_k127_6590732_15 ERCC4 domain - - - 0.000000000000000000000000000000000000000000000002246 181.0
TLS2_k127_6590732_16 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000009564 164.0
TLS2_k127_6590732_17 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000001015 122.0
TLS2_k127_6590732_18 Histidine kinase K07675,K14988,K20263 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000008754 74.0
TLS2_k127_6590732_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 511.0
TLS2_k127_6590732_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 456.0
TLS2_k127_6590732_4 ATPases associated with a variety of cellular activities K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 427.0
TLS2_k127_6590732_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 419.0
TLS2_k127_6590732_6 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 416.0
TLS2_k127_6590732_7 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 333.0
TLS2_k127_6590732_8 Polysaccharide pyruvyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 333.0
TLS2_k127_6590732_9 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 326.0
TLS2_k127_6596174_0 - - - - 4.506e-299 939.0
TLS2_k127_6596503_0 radical SAM domain protein - - - 4.033e-196 623.0
TLS2_k127_6596503_1 Domain of unknown function (DUF3463) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 614.0
TLS2_k127_6596503_2 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 498.0
TLS2_k127_6596503_3 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000002369 250.0
TLS2_k127_6596503_4 HAD-hyrolase-like - - - 0.000000000000000000000000000000001281 139.0
TLS2_k127_6596503_5 Tetratricopeptide repeat - - - 0.000000000000000001057 96.0
TLS2_k127_6596503_6 peptidyl-tyrosine sulfation - - - 0.00005853 54.0
TLS2_k127_6596564_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 573.0
TLS2_k127_6596564_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 396.0
TLS2_k127_6596564_2 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 315.0
TLS2_k127_6596564_3 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 291.0
TLS2_k127_6596564_4 Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006249 241.0
TLS2_k127_6596564_5 Protein of unknown function (DUF3445) K22342 - 1.14.13.238 0.00000000000000000000000000003103 128.0
TLS2_k127_6596564_6 - - - - 0.000000000001523 77.0
TLS2_k127_6597703_0 Biotin and Thiamin Synthesis associated domain K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 468.0
TLS2_k127_6597703_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 437.0
TLS2_k127_6597703_10 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000002666 141.0
TLS2_k127_6597703_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000107 128.0
TLS2_k127_6597703_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000001925 133.0
TLS2_k127_6597703_13 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000142 115.0
TLS2_k127_6597703_14 Hep Hag repeat protein - - - 0.000000000000000000000005157 119.0
TLS2_k127_6597703_15 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000002267 94.0
TLS2_k127_6597703_17 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000009374 68.0
TLS2_k127_6597703_2 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 387.0
TLS2_k127_6597703_3 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 338.0
TLS2_k127_6597703_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 347.0
TLS2_k127_6597703_5 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001958 273.0
TLS2_k127_6597703_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001396 275.0
TLS2_k127_6597703_7 Hep Hag repeat protein K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000791 244.0
TLS2_k127_6597703_8 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000003026 201.0
TLS2_k127_6597703_9 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000003862 193.0
TLS2_k127_6603504_0 aerobic electron transport chain K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 591.0
TLS2_k127_6603504_1 Cysteine export CydDC family ABC transporter permease subunit ATP-binding protein CydD K06148,K16013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 504.0
TLS2_k127_6603504_10 - - - - 0.0000000001746 66.0
TLS2_k127_6603504_11 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000001271 63.0
TLS2_k127_6603504_12 Protein of unknown function (DUF3618) - - - 0.000003301 55.0
TLS2_k127_6603504_13 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.00001061 54.0
TLS2_k127_6603504_2 TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K16012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 433.0
TLS2_k127_6603504_3 oxidative phosphorylation K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 397.0
TLS2_k127_6603504_4 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000001283 269.0
TLS2_k127_6603504_5 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.000000000000000000000000000000000000000000000000000000000000004521 223.0
TLS2_k127_6603504_6 PFAM PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000001716 198.0
TLS2_k127_6603504_7 - - - - 0.000000000000000000000000000000000000000000000002136 178.0
TLS2_k127_6603504_9 PFAM PBS lyase HEAT-like repeat - - - 0.000000000005362 80.0
TLS2_k127_6617039_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 477.0
TLS2_k127_6617039_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 469.0
TLS2_k127_6617039_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000001103 211.0
TLS2_k127_6617039_11 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000001136 207.0
TLS2_k127_6617039_12 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000001721 198.0
TLS2_k127_6617039_13 DNA integration K07497 - - 0.000000000000000000000000000000000000000000000000003526 198.0
TLS2_k127_6617039_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000116 182.0
TLS2_k127_6617039_15 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000005043 187.0
TLS2_k127_6617039_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000007798 177.0
TLS2_k127_6617039_17 Mu transposase, C-terminal K07497 - - 0.000000000000000000000000000000000000000000002586 169.0
TLS2_k127_6617039_18 Cupin domain - - - 0.0000000000000000000000000000000000000001367 158.0
TLS2_k127_6617039_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000533 146.0
TLS2_k127_6617039_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 392.0
TLS2_k127_6617039_20 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000006455 129.0
TLS2_k127_6617039_21 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000005507 128.0
TLS2_k127_6617039_22 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000315 128.0
TLS2_k127_6617039_23 Ribosomal proteins 50S L24/mitochondrial 39S L24 K02895 - - 0.000000000000000000000000005997 111.0
TLS2_k127_6617039_24 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000249 100.0
TLS2_k127_6617039_25 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001031 73.0
TLS2_k127_6617039_26 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000438 57.0
TLS2_k127_6617039_3 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001793 287.0
TLS2_k127_6617039_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003707 274.0
TLS2_k127_6617039_5 PFAM Resolvase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001618 266.0
TLS2_k127_6617039_6 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007306 267.0
TLS2_k127_6617039_7 Tyrosine phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000003134 243.0
TLS2_k127_6617039_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000002464 224.0
TLS2_k127_6617039_9 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000595 225.0
TLS2_k127_6620525_0 Glycosyl hydrolases family 32 K03332 - 3.2.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 490.0
TLS2_k127_6620525_1 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 417.0
TLS2_k127_6620525_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 426.0
TLS2_k127_6620525_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 374.0
TLS2_k127_6620525_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 332.0
TLS2_k127_6620525_5 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003663 297.0
TLS2_k127_6620525_7 Outer Membrane Lipoprotein K03098 GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.000000000000007407 76.0
TLS2_k127_6620525_8 - - - - 0.000000000001049 75.0
TLS2_k127_6620525_9 FG-GAP repeat protein - - - 0.00009277 45.0
TLS2_k127_6633512_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000295 278.0
TLS2_k127_6633512_1 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000003192 207.0
TLS2_k127_6633512_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000000001044 129.0
TLS2_k127_6633512_4 - - - - 0.000000000000000072 84.0
TLS2_k127_6633512_5 HD domain - - - 0.00000000000000007318 83.0
TLS2_k127_6635160_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 419.0
TLS2_k127_6635160_1 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 392.0
TLS2_k127_6635160_2 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004113 255.0
TLS2_k127_6635160_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004494 236.0
TLS2_k127_6635160_4 Phosphopantetheine attachment site - - - 0.00000000000000162 82.0
TLS2_k127_6636705_0 Helix-hairpin-helix containing domain - - - 4.807e-294 918.0
TLS2_k127_6636705_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.723e-206 652.0
TLS2_k127_6636705_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 547.0
TLS2_k127_6636705_3 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 359.0
TLS2_k127_6636705_4 Domain of unknown function (DUF4214) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 320.0
TLS2_k127_6636705_5 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002557 280.0
TLS2_k127_6636705_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000003193 121.0
TLS2_k127_663696_0 ASPIC UnbV domain protein - - - 1.382e-282 910.0
TLS2_k127_663696_1 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 432.0
TLS2_k127_663696_10 Protein of unknown function (DUF2752) - - - 0.000000000000000000444 93.0
TLS2_k127_663696_11 Transcriptional regulatory protein, C terminal - - - 0.000000001152 72.0
TLS2_k127_663696_12 RDD family K18481 - - 0.00000001669 64.0
TLS2_k127_663696_2 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 387.0
TLS2_k127_663696_3 selenide, water dikinase activity K01008,K04487 - 2.7.9.3,2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 331.0
TLS2_k127_663696_5 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000004318 263.0
TLS2_k127_663696_6 Rhomboid family - - - 0.0000000000000000000000000000000000000098 156.0
TLS2_k127_663696_7 integral membrane protein - - - 0.0000000000000000000000000000008918 135.0
TLS2_k127_663696_8 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000002974 104.0
TLS2_k127_663696_9 - - - - 0.000000000000000000004257 102.0
TLS2_k127_6707107_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 4.605e-198 628.0
TLS2_k127_6707107_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 523.0
TLS2_k127_6707107_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009727 448.0
TLS2_k127_6707107_3 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 428.0
TLS2_k127_6707107_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000009363 173.0
TLS2_k127_6710974_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003301 253.0
TLS2_k127_6710974_1 beta-lactamase - - - 0.000000000000000000000000000000000000003209 156.0
TLS2_k127_6711813_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 461.0
TLS2_k127_6711813_1 helix_turn_helix, mercury resistance K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 293.0
TLS2_k127_6711813_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002343 248.0
TLS2_k127_6721749_0 Pyruvate:ferredoxin oxidoreductase core domain II K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0 1855.0
TLS2_k127_6721749_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 608.0
TLS2_k127_6721749_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 612.0
TLS2_k127_6721749_3 Domain of unknown function (DUF4202) - - - 0.000000000000000000000000000000000000000000000000000000002323 210.0
TLS2_k127_6721749_4 - - - - 0.0000000000000317 81.0
TLS2_k127_6721749_5 - - - - 0.000006036 55.0
TLS2_k127_6721749_6 phosphorelay signal transduction system K01338 - 3.4.21.53 0.0002065 44.0
TLS2_k127_6724751_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K07307 - - 2.083e-319 993.0
TLS2_k127_6724751_1 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00366 - 1.7.7.1 7.229e-217 690.0
TLS2_k127_6724751_2 Oxidoreductase NAD-binding domain K00380 - 1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 586.0
TLS2_k127_6724751_3 ATPase (AAA superfamily K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 460.0
TLS2_k127_6743101_0 4Fe-4S dicluster domain K00184 - - 6.107e-309 985.0
TLS2_k127_6743101_1 Adenylylsulphate kinase K00955 - 2.7.1.25,2.7.7.4 4.562e-222 715.0
TLS2_k127_6743101_2 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.171e-221 705.0
TLS2_k127_6743101_3 Polysulphide reductase, NrfD K00185 - - 2.26e-219 690.0
TLS2_k127_6743101_4 sulfate reduction K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 387.0
TLS2_k127_6743101_5 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 287.0
TLS2_k127_6743101_6 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000001004 221.0
TLS2_k127_6743101_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000001221 180.0
TLS2_k127_6749300_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 455.0
TLS2_k127_6749300_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 417.0
TLS2_k127_6749300_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000003576 158.0
TLS2_k127_6750581_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 2.602e-225 725.0
TLS2_k127_6750581_1 Protein of unknown function, DUF255 K06888 - - 2.682e-196 632.0
TLS2_k127_6750581_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 324.0
TLS2_k127_6750581_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002677 259.0
TLS2_k127_6750581_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000416 119.0
TLS2_k127_6750581_5 Transcriptional regulator - - - 0.00000000000000000000000006625 113.0
TLS2_k127_6750581_6 CAAX protease self-immunity K07052 - - 0.0000000000000005319 87.0
TLS2_k127_6750581_7 - - - - 0.000000002432 66.0
TLS2_k127_6768808_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009644 277.0
TLS2_k127_6768808_1 Nucleoside diphosphate kinase K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000525 217.0
TLS2_k127_6768808_2 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.00000000000000000000000000002448 122.0
TLS2_k127_6812482_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 295.0
TLS2_k127_6812482_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002285 280.0
TLS2_k127_6812482_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003079 235.0
TLS2_k127_6812482_3 Methyltransferase domain - - - 0.00000000000000000000000001642 121.0
TLS2_k127_6812482_4 Methyltransferase FkbM domain - - - 0.00000000000000000000495 103.0
TLS2_k127_6812482_5 Glycosyl transferase 4-like domain K02844 - - 0.000007758 52.0
TLS2_k127_6816075_0 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 473.0
TLS2_k127_6816075_1 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 395.0
TLS2_k127_6816075_2 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 351.0
TLS2_k127_6816075_3 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 330.0
TLS2_k127_6816075_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 316.0
TLS2_k127_6816075_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000007209 220.0
TLS2_k127_6816075_6 CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000001637 208.0
TLS2_k127_6816075_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001386 180.0
TLS2_k127_6816075_8 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.00000000000000000000006852 111.0
TLS2_k127_6816093_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 486.0
TLS2_k127_6816093_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 353.0
TLS2_k127_6816093_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000006616 217.0
TLS2_k127_6816093_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000001271 168.0
TLS2_k127_6816093_4 competence protein - - - 0.000000000000000000000000000000000000001041 165.0
TLS2_k127_6816093_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000002128 129.0
TLS2_k127_6816093_6 CAAX protease self-immunity - - - 0.00000000000000000003878 102.0
TLS2_k127_6816093_7 - - - - 0.0000000000000003546 79.0
TLS2_k127_6816093_9 O-antigen ligase like membrane protein - - - 0.00001857 58.0
TLS2_k127_683173_0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 425.0
TLS2_k127_683173_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000001325 168.0
TLS2_k127_683173_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000002138 154.0
TLS2_k127_6873661_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.298e-239 758.0
TLS2_k127_6873661_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.815e-235 741.0
TLS2_k127_6873661_10 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000009405 219.0
TLS2_k127_6873661_11 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000005763 126.0
TLS2_k127_6873661_12 PFAM Uncharacterised protein family UPF0175 - - - 0.000001232 54.0
TLS2_k127_6873661_13 PD-(D/E)XK nuclease superfamily - - - 0.0009364 50.0
TLS2_k127_6873661_2 Protein of unknown function (DUF1593) - - - 7.604e-204 644.0
TLS2_k127_6873661_3 Belongs to the glycosyl hydrolase 30 family K01181,K15921,K15924 - 3.2.1.136,3.2.1.55,3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 566.0
TLS2_k127_6873661_4 Glycoside hydrolase family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 314.0
TLS2_k127_6873661_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 288.0
TLS2_k127_6873661_6 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001068 281.0
TLS2_k127_6873661_7 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005928 284.0
TLS2_k127_6873661_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000006861 219.0
TLS2_k127_6873661_9 Domain of unknown function (DUF4832) - - - 0.00000000000000000000000000000000000000000000000000000000003828 224.0
TLS2_k127_6878458_0 Peptidase MA superfamily - - - 1.414e-252 810.0
TLS2_k127_6878458_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008097 538.0
TLS2_k127_6878458_2 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 541.0
TLS2_k127_6878458_3 PFAM ATPase associated with various cellular activities AAA_3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 477.0
TLS2_k127_6878458_4 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 406.0
TLS2_k127_6878458_5 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 366.0
TLS2_k127_6878458_6 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000001652 240.0
TLS2_k127_6887250_0 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 405.0
TLS2_k127_6887250_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000008811 174.0
TLS2_k127_6896310_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.911e-199 630.0
TLS2_k127_6896310_1 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 607.0
TLS2_k127_6896310_2 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 302.0
TLS2_k127_6896310_3 COG3119 Arylsulfatase A K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003115 287.0
TLS2_k127_6896480_0 - - - - 5.429e-205 646.0
TLS2_k127_6896480_1 DEAD DEAH box helicase K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 321.0
TLS2_k127_6896480_2 DNA repair - - - 0.00000000000000002056 87.0
TLS2_k127_6917618_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1233.0
TLS2_k127_6917618_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1027.0
TLS2_k127_6917618_10 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000002442 243.0
TLS2_k127_6917618_11 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005852 228.0
TLS2_k127_6917618_12 CbiX - - - 0.000000000000000000000000000000000000000000000000000000000000129 223.0
TLS2_k127_6917618_13 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000004331 216.0
TLS2_k127_6917618_14 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000007976 175.0
TLS2_k127_6917618_15 Dihydrofolate reductase K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000774 165.0
TLS2_k127_6917618_16 Armadillo/beta-catenin-like repeats - - - 0.00000000000000003358 93.0
TLS2_k127_6917618_17 PFAM Integral membrane protein TerC K05794 - - 0.000000000007042 70.0
TLS2_k127_6917618_2 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.74e-252 805.0
TLS2_k127_6917618_3 cell wall glycoprotein biosynthetic process - - - 5.915e-237 736.0
TLS2_k127_6917618_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.254e-219 697.0
TLS2_k127_6917618_5 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 567.0
TLS2_k127_6917618_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 433.0
TLS2_k127_6917618_7 3-dehydroquinate synthase K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 416.0
TLS2_k127_6917618_8 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 365.0
TLS2_k127_6917618_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004341 280.0
TLS2_k127_6924098_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 356.0
TLS2_k127_6924098_1 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004295 252.0
TLS2_k127_6924098_2 reverse transcriptase K15342 - - 0.000000000000000000000000000000000000000000000000000000000000000002181 244.0
TLS2_k127_6924098_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000006433 70.0
TLS2_k127_6924098_4 Metalloprotease - - - 0.0000001452 65.0
TLS2_k127_6924098_5 phospholipase C K21302 - 3.1.3.64 0.000003038 61.0
TLS2_k127_6925000_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 478.0
TLS2_k127_6925000_1 Belongs to the beta-ketoacyl-ACP synthases family K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 475.0
TLS2_k127_6925000_2 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 394.0
TLS2_k127_6925000_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006472 244.0
TLS2_k127_6925000_4 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000003374 153.0
TLS2_k127_6925000_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000017 80.0
TLS2_k127_6925000_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00001591 47.0
TLS2_k127_6925000_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000334 50.0
TLS2_k127_6936382_0 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 565.0
TLS2_k127_6936382_1 AAA ATPase, central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008992 526.0
TLS2_k127_6936382_2 Endoribonuclease that initiates mRNA decay K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 480.0
TLS2_k127_6936382_3 Protein of unknown function (DUF1593) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 396.0
TLS2_k127_6936382_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000002212 119.0
TLS2_k127_6936382_5 nuclear chromosome segregation - - - 0.00000001318 65.0
TLS2_k127_6942546_0 NAD synthase - - - 5.533e-194 619.0
TLS2_k127_6942546_1 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 553.0
TLS2_k127_6942546_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 289.0
TLS2_k127_6942546_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000001884 138.0
TLS2_k127_6942546_4 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000118 121.0
TLS2_k127_6942546_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.00000000000000000000000001581 111.0
TLS2_k127_6942747_0 FtsX-like permease family - - - 5.086e-255 825.0
TLS2_k127_6942747_1 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 574.0
TLS2_k127_6942747_10 chorismate lyase activity - - - 0.0000000000000000000000000003461 128.0
TLS2_k127_6942747_11 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000006696 97.0
TLS2_k127_6942747_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 548.0
TLS2_k127_6942747_3 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 428.0
TLS2_k127_6942747_4 PFAM Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 393.0
TLS2_k127_6942747_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000867 386.0
TLS2_k127_6942747_6 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000001649 242.0
TLS2_k127_6942747_7 - - - - 0.000000000000000000000000000000000000000000000000003035 191.0
TLS2_k127_6942747_8 Bacterial regulatory protein, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000001623 184.0
TLS2_k127_6942747_9 Thioesterase K01075,K07107 - 3.1.2.23 0.0000000000000000000000000000000000000006341 152.0
TLS2_k127_6953696_0 Pfam:N_methyl_2 - - - 0.000000000000000000000000000000000000001063 156.0
TLS2_k127_6953696_1 Endonuclease Exonuclease Phosphatase - - - 0.000008181 59.0
TLS2_k127_6989330_0 zinc ion binding K02347,K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 494.0
TLS2_k127_6989330_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 399.0
TLS2_k127_6989330_10 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000000000000000000000000004275 121.0
TLS2_k127_6989330_2 Ni2 binding GTPase involved in regulation of expression and maturation of urease and hydrogenase K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
TLS2_k127_6989330_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 291.0
TLS2_k127_6989330_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005303 267.0
TLS2_k127_6989330_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000001441 249.0
TLS2_k127_6989330_6 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002278 232.0
TLS2_k127_6989330_7 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000007405 201.0
TLS2_k127_6989330_8 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000002241 141.0
TLS2_k127_6989330_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000001463 128.0
TLS2_k127_6992960_0 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 354.0
TLS2_k127_6992960_1 COG1349 Transcriptional regulators of sugar metabolism - - - 0.000000000000000000000000000000000000000000000000974 184.0
TLS2_k127_6992960_2 BMC - - - 0.000000000000000000000000000000000005823 139.0
TLS2_k127_6992960_3 BMC K04027 - - 0.0000000000000000000000000000000001123 134.0
TLS2_k127_6992960_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000001803 81.0
TLS2_k127_6992960_5 Glycosyl transferases group 1 - - - 0.000293 51.0
TLS2_k127_699727_0 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 352.0
TLS2_k127_699727_1 restriction endonuclease - - - 0.0000000000000000000000000000000000000000004461 158.0
TLS2_k127_699727_2 HAF family - - - 0.00000000000000000000000000000000000002855 150.0
TLS2_k127_699727_3 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000001159 125.0
TLS2_k127_699727_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.00002841 57.0
TLS2_k127_699727_5 protein conserved in bacteria K09919 - - 0.00009641 49.0
TLS2_k127_699727_6 HAF family - - - 0.0008007 44.0
TLS2_k127_7003205_0 Alpha/beta hydrolase family - - - 6.565e-268 842.0
TLS2_k127_7003205_1 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 523.0
TLS2_k127_7003205_10 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000001138 214.0
TLS2_k127_7003205_11 PFAM Bacterial regulatory proteins, lacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000003487 213.0
TLS2_k127_7003205_12 lipid kinase activity - - - 0.0000000000000000000000000000004907 135.0
TLS2_k127_7003205_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000004592 123.0
TLS2_k127_7003205_14 AAA domain K02282 - - 0.00000000000000002308 87.0
TLS2_k127_7003205_15 zinc-ribbon domain - - - 0.0000000000001698 76.0
TLS2_k127_7003205_16 Prokaryotic N-terminal methylation motif - - - 0.0000000000008641 79.0
TLS2_k127_7003205_17 - - - - 0.000000000001584 79.0
TLS2_k127_7003205_18 - - - - 0.0002146 49.0
TLS2_k127_7003205_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 522.0
TLS2_k127_7003205_3 Alanine dehydrogenase/PNT, C-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 520.0
TLS2_k127_7003205_4 PFAM type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 407.0
TLS2_k127_7003205_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07083,K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 415.0
TLS2_k127_7003205_6 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 400.0
TLS2_k127_7003205_7 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 374.0
TLS2_k127_7003205_8 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 359.0
TLS2_k127_7003205_9 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000385 253.0
TLS2_k127_7013943_0 sigma-54 factor interaction domain-containing protein K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 471.0
TLS2_k127_7013943_1 PFAM type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003632 245.0
TLS2_k127_7021_0 COG3119 Arylsulfatase A and related enzymes K01137 - 3.1.6.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 398.0
TLS2_k127_7021_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000001638 126.0
TLS2_k127_7021_2 PFAM Class I peptide chain release factor - - - 0.000000000000000000000000001101 120.0
TLS2_k127_7021_3 and related - - - 0.00000000000000000000783 93.0
TLS2_k127_7041469_0 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 442.0
TLS2_k127_7041469_1 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 356.0
TLS2_k127_7041469_2 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002935 279.0
TLS2_k127_7041469_3 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002015 261.0
TLS2_k127_7041469_4 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000001248 203.0
TLS2_k127_7041469_5 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000001168 181.0
TLS2_k127_7041469_6 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000001824 173.0
TLS2_k127_7041469_7 Beta-lactamase superfamily domain K03476 - - 0.000000000000000000000000000000000000000001046 166.0
TLS2_k127_7041469_9 PFAM Transposase IS200 like - - - 0.0000006764 55.0
TLS2_k127_7043574_0 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 481.0
TLS2_k127_7043574_1 cephalosporin-C deacetylase activity - - - 0.0000000000000000000000000000000000000000000000003309 177.0
TLS2_k127_7043574_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000000001399 133.0
TLS2_k127_7060321_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003775 294.0
TLS2_k127_7060321_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000003675 85.0
TLS2_k127_7060321_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000002569 69.0
TLS2_k127_7060321_3 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 0.000001893 53.0
TLS2_k127_7061013_0 PFAM Glycoside hydrolase 15-related - - - 2.661e-201 652.0
TLS2_k127_7061013_1 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 544.0
TLS2_k127_7061013_2 Alginate export - - - 0.000000000000000000000000000000000000000000000000000002256 194.0
TLS2_k127_7061013_3 Phospholipid N-methyltransferase - - - 0.0000000000000000000000000000000000000000006277 165.0
TLS2_k127_7061013_4 efflux transmembrane transporter activity - - - 0.00002531 53.0
TLS2_k127_7077713_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 1.315e-284 891.0
TLS2_k127_7077713_1 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 506.0
TLS2_k127_7077713_2 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000462 166.0
TLS2_k127_7077713_3 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000001411 159.0
TLS2_k127_7077713_4 Binding-protein-dependent transport system inner membrane component K02042 - - 0.0000000000000000000000000000000000000003644 158.0
TLS2_k127_7077713_5 acetyltransferase - - - 0.00000000000000000000000000000000002943 143.0
TLS2_k127_7077713_6 PFAM PQQ enzyme repeat - - - 0.0000000000000000000000000000000004024 146.0
TLS2_k127_7077713_7 Phosphonate ABC transporter K02044 - - 0.000000000000000000000001617 116.0
TLS2_k127_7077713_8 Protein of unknown function (DUF1549) - - - 0.00000000000000000000000237 108.0
TLS2_k127_7081510_0 FAD dependent oxidoreductase - - - 7.454e-243 763.0
TLS2_k127_7081510_1 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 514.0
TLS2_k127_7081510_10 cell adhesion K02650 - - 0.000000000002474 77.0
TLS2_k127_7081510_11 Pirin K06911 - - 0.00000006605 54.0
TLS2_k127_7081510_2 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 481.0
TLS2_k127_7081510_3 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 401.0
TLS2_k127_7081510_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 300.0
TLS2_k127_7081510_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 301.0
TLS2_k127_7081510_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000001669 230.0
TLS2_k127_7081510_7 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000007227 189.0
TLS2_k127_7081510_8 Cytochrome c - - - 0.0000000000000001188 92.0
TLS2_k127_7081510_9 Pirin K06911 - - 0.0000000000002662 72.0
TLS2_k127_7086665_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 466.0
TLS2_k127_7086665_1 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 327.0
TLS2_k127_7086665_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 313.0
TLS2_k127_7086665_3 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004022 265.0
TLS2_k127_7101387_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1112.0
TLS2_k127_7101387_1 Proteasomal ATPase OB/ID domain K13527 - - 6.954e-196 625.0
TLS2_k127_7101387_10 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001946 192.0
TLS2_k127_7101387_11 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000037 190.0
TLS2_k127_7101387_12 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000009161 191.0
TLS2_k127_7101387_13 - - - - 0.0000000000000000000000000000000000000000000002217 173.0
TLS2_k127_7101387_14 Peptidase M23 - - - 0.000000000000000000000000000000000000000000002059 185.0
TLS2_k127_7101387_15 Proteasome subunit K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000004911 172.0
TLS2_k127_7101387_16 May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes - - - 0.0000000000000000007672 87.0
TLS2_k127_7101387_17 cyclic nucleotide binding K10914 - - 0.00000000000000003327 93.0
TLS2_k127_7101387_18 CAAX prenyl protease N-terminal, five membrane helices - - - 0.000000000000003877 79.0
TLS2_k127_7101387_19 Beta-galactosidase K01190 - 3.2.1.23 0.0000004709 64.0
TLS2_k127_7101387_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 535.0
TLS2_k127_7101387_20 Protein of unknown function (DUF3307) - - - 0.0000008589 57.0
TLS2_k127_7101387_21 GYD domain - - - 0.000001064 52.0
TLS2_k127_7101387_3 Pup-ligase protein K20814 - 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 526.0
TLS2_k127_7101387_4 UTP:glucose-1-phosphate uridylyltransferase activity K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 467.0
TLS2_k127_7101387_5 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 442.0
TLS2_k127_7101387_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 419.0
TLS2_k127_7101387_7 WYL domain K13572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001483 284.0
TLS2_k127_7101387_8 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000005826 227.0
TLS2_k127_7101387_9 Proteasome subunit K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000005173 227.0
TLS2_k127_710243_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 489.0
TLS2_k127_710243_1 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 340.0
TLS2_k127_710243_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000008247 213.0
TLS2_k127_710243_3 Outer membrane lipoprotein K05807 - - 0.000000000000000000000000000000000000000000000000000001382 204.0
TLS2_k127_710243_4 PAS PAC sensor signal transduction histidine kinase - - - 0.000000000000000000000000000006746 124.0
TLS2_k127_710243_5 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000002408 102.0
TLS2_k127_710243_6 Lipopolysaccharide-assembly - - - 0.0000000000000002199 88.0
TLS2_k127_710243_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000003815 79.0
TLS2_k127_710243_8 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000686 59.0
TLS2_k127_7108089_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.036e-298 948.0
TLS2_k127_7108089_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.088e-290 918.0
TLS2_k127_7108089_10 Type II transport protein GspH K08084 - - 0.0004736 50.0
TLS2_k127_7108089_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 295.0
TLS2_k127_7108089_3 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002632 251.0
TLS2_k127_7108089_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000003601 234.0
TLS2_k127_7108089_5 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000002973 239.0
TLS2_k127_7108089_6 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000000001098 107.0
TLS2_k127_7108089_7 general secretion pathway protein K02459 - - 0.000000336 61.0
TLS2_k127_7108089_8 Putative restriction endonuclease - - - 0.00001163 56.0
TLS2_k127_7108089_9 Prokaryotic N-terminal methylation motif K02458 - - 0.0004153 49.0
TLS2_k127_7118441_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.097e-213 673.0
TLS2_k127_7118441_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000894 617.0
TLS2_k127_7118441_2 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term K17108 - 3.2.1.45 0.00000000000000000000000000000000000000000000000000000000003018 209.0
TLS2_k127_7142138_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1298.0
TLS2_k127_7142138_1 SMART helicase c2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 362.0
TLS2_k127_7142138_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005238 256.0
TLS2_k127_7144555_0 glucan 1,4-alpha-glucosidase activity - - - 0.0 1040.0
TLS2_k127_7144555_1 Pfam:KaiC K08482 - - 3.657e-209 665.0
TLS2_k127_7144555_10 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000005734 164.0
TLS2_k127_7144555_11 KaiB K08481 - - 0.000000000000000000000000000000000000005026 147.0
TLS2_k127_7144555_12 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000000000000000000002225 152.0
TLS2_k127_7144555_13 KaiB domain K08481 - - 0.000000000000000000000000000000001645 132.0
TLS2_k127_7144555_14 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000006646 132.0
TLS2_k127_7144555_15 histidine kinase A domain protein - - - 0.00000000000000000000000000004051 134.0
TLS2_k127_7144555_16 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000007308 107.0
TLS2_k127_7144555_17 excinuclease ABC activity K03703 - - 0.0000000000000000001425 100.0
TLS2_k127_7144555_19 - - - - 0.00001225 51.0
TLS2_k127_7144555_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 437.0
TLS2_k127_7144555_3 Transfers the fatty acyl group on membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 394.0
TLS2_k127_7144555_4 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 376.0
TLS2_k127_7144555_5 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 354.0
TLS2_k127_7144555_6 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 316.0
TLS2_k127_7144555_7 PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009605 268.0
TLS2_k127_7144555_8 3-beta hydroxysteroid dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000008704 223.0
TLS2_k127_7144555_9 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000005278 203.0
TLS2_k127_7157452_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 490.0
TLS2_k127_7157452_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 403.0
TLS2_k127_7157452_2 Component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 339.0
TLS2_k127_7187338_0 Pfam:N_methyl_2 - - - 0.000000000000009319 84.0
TLS2_k127_7187338_1 general secretion pathway protein K02456 - - 0.000000000001144 78.0
TLS2_k127_7187338_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0001614 44.0
TLS2_k127_7209559_0 intracellular protein transport - - - 8.923e-261 840.0
TLS2_k127_7209559_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.586e-196 642.0
TLS2_k127_7209559_10 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 302.0
TLS2_k127_7209559_11 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000032 296.0
TLS2_k127_7209559_12 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006234 274.0
TLS2_k127_7209559_13 E-Z type HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001563 288.0
TLS2_k127_7209559_14 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000231 262.0
TLS2_k127_7209559_15 Bifunctional nuclease - - - 0.000000000000000000000000000000000000000000000000000001022 204.0
TLS2_k127_7209559_16 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000000001067 200.0
TLS2_k127_7209559_17 negative regulation of phosphate transmembrane transport K01104,K02039,K03741 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 0.0000000000000000000000000000000000000000001469 174.0
TLS2_k127_7209559_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.00000000000000000000008234 106.0
TLS2_k127_7209559_19 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000002541 97.0
TLS2_k127_7209559_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 537.0
TLS2_k127_7209559_3 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 541.0
TLS2_k127_7209559_4 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 479.0
TLS2_k127_7209559_5 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 462.0
TLS2_k127_7209559_6 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 414.0
TLS2_k127_7209559_7 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 406.0
TLS2_k127_7209559_8 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 383.0
TLS2_k127_7209559_9 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 377.0
TLS2_k127_721393_0 FtsX-like permease family - - - 9.587e-267 844.0
TLS2_k127_721393_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 621.0
TLS2_k127_721393_10 Bacterial PH domain K09167 - - 0.00000000000000000004489 96.0
TLS2_k127_721393_11 SNARE associated Golgi protein - - - 0.00000000000000002386 92.0
TLS2_k127_721393_12 cell adhesion K02650 - - 0.0000000003437 71.0
TLS2_k127_721393_2 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 452.0
TLS2_k127_721393_3 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 426.0
TLS2_k127_721393_4 PFAM Na H antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 392.0
TLS2_k127_721393_5 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 336.0
TLS2_k127_721393_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 326.0
TLS2_k127_721393_7 Ribose/Galactose Isomerase - - - 0.000000000000000000000000000000000000000000000000000000008308 206.0
TLS2_k127_721393_8 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000000000000000002163 195.0
TLS2_k127_721393_9 Bacterial PH domain K08981 - - 0.000000000000000000000000000000000000000000004163 183.0
TLS2_k127_7218169_0 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 492.0
TLS2_k127_7236184_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 3.867e-196 619.0
TLS2_k127_7236184_1 and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 477.0
TLS2_k127_7236184_2 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 451.0
TLS2_k127_7236184_3 Peptidase, M16 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 398.0
TLS2_k127_7236184_4 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 347.0
TLS2_k127_7236184_5 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 355.0
TLS2_k127_7236184_6 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 282.0
TLS2_k127_7236184_7 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000001979 248.0
TLS2_k127_7236184_8 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000004066 162.0
TLS2_k127_7236184_9 - - - - 0.00000000000003768 75.0
TLS2_k127_72447_0 Alpha amylase, catalytic domain K00690 - 2.4.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 534.0
TLS2_k127_72447_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 520.0
TLS2_k127_72447_10 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 350.0
TLS2_k127_72447_11 rRNA (cytosine-C5-)-methyltransferase activity K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 352.0
TLS2_k127_72447_12 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 328.0
TLS2_k127_72447_13 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 314.0
TLS2_k127_72447_14 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000003056 225.0
TLS2_k127_72447_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001445 215.0
TLS2_k127_72447_16 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000002521 217.0
TLS2_k127_72447_17 - - - - 0.00000000000000000000000000000000000000000000000001423 188.0
TLS2_k127_72447_18 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001885 185.0
TLS2_k127_72447_19 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000273 181.0
TLS2_k127_72447_2 COGs COG0673 dehydrogenase and related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 505.0
TLS2_k127_72447_20 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000004012 165.0
TLS2_k127_72447_21 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000004428 156.0
TLS2_k127_72447_22 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000001218 135.0
TLS2_k127_72447_23 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000004622 126.0
TLS2_k127_72447_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000002917 86.0
TLS2_k127_72447_25 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000003634 82.0
TLS2_k127_72447_3 Acyl-homoserine-lactone synthase K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 503.0
TLS2_k127_72447_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 495.0
TLS2_k127_72447_5 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 478.0
TLS2_k127_72447_6 synthase K15431,K16167,K16424,K19580 - 2.3.1.233,2.3.1.246,2.3.1.253 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 412.0
TLS2_k127_72447_7 selenocysteine insertion sequence binding K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 422.0
TLS2_k127_72447_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 383.0
TLS2_k127_72447_9 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 356.0
TLS2_k127_726322_0 UDP-N-acetyl-D-mannosamine dehydrogenase activity K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 567.0
TLS2_k127_726322_1 Polysaccharide biosynthesis protein CapD - - - 0.00000000000009333 74.0
TLS2_k127_7285552_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006622 300.0
TLS2_k127_7286408_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 3.006e-204 661.0
TLS2_k127_7286408_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 486.0
TLS2_k127_7286408_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 369.0
TLS2_k127_7286408_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000048 281.0
TLS2_k127_7286408_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000005504 206.0
TLS2_k127_7286408_5 Belongs to the P(II) protein family - - - 0.000000000000000000176 90.0
TLS2_k127_7286408_6 iron ion homeostasis K04758 GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015684,GO:0030001,GO:0033554,GO:0034220,GO:0034755,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070627,GO:0070838,GO:0072511,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098707,GO:0098711,GO:0098739,GO:0099587,GO:1903874 - 0.0000000000000001829 83.0
TLS2_k127_7286408_7 FeoA domain - - - 0.0000002139 57.0
TLS2_k127_7286466_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 475.0
TLS2_k127_7286466_1 SERine Proteinase INhibitors K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 317.0
TLS2_k127_7286466_10 Domain of unknown function (DUF5060) - - - 0.000000926 55.0
TLS2_k127_7286466_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000002933 227.0
TLS2_k127_7286466_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000004843 162.0
TLS2_k127_7286466_4 Uncharacterized protein conserved in bacteria (DUF2314) - - - 0.000000000000000000001584 102.0
TLS2_k127_7286466_5 Protein of unknown function (DUF504) - - - 0.0000000000000001864 82.0
TLS2_k127_7286466_6 phosphoenolpyruvate-dependent sugar phosphotransferase system K02784,K11189 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005981,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008047,GO:0008150,GO:0008152,GO:0008643,GO:0008965,GO:0008982,GO:0009401,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015144,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0019197,GO:0019222,GO:0022804,GO:0022857,GO:0030234,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032881,GO:0032991,GO:0034219,GO:0043085,GO:0043467,GO:0043470,GO:0043471,GO:0044093,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045819,GO:0045913,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0065009,GO:0070873,GO:0070875,GO:0071702,GO:0080090,GO:0098772 - 0.0000000000000009066 80.0
TLS2_k127_7286466_7 - - - - 0.0000000000006113 76.0
TLS2_k127_7286466_8 anaphase-promoting complex-dependent catabolic process - - - 0.0000000000007549 70.0
TLS2_k127_7286466_9 WD-40 repeat - - - 0.000000001304 67.0
TLS2_k127_7337756_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 494.0
TLS2_k127_7337756_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 475.0
TLS2_k127_7337756_10 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000006187 100.0
TLS2_k127_7337756_11 alginic acid biosynthetic process K09815,K15727,K20276 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000005726 105.0
TLS2_k127_7337756_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 488.0
TLS2_k127_7337756_3 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 340.0
TLS2_k127_7337756_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 308.0
TLS2_k127_7337756_5 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 275.0
TLS2_k127_7337756_6 Prepilin-type N-terminal cleavage methylation domain - - - 0.00000000000000000000000000000000000000000000000000000002706 205.0
TLS2_k127_7337756_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000001364 206.0
TLS2_k127_7337756_8 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000006544 201.0
TLS2_k127_7337756_9 Belongs to the bacterial solute-binding protein 9 family - - - 0.00000000000000000000000000000000000000000001654 171.0
TLS2_k127_7346997_0 von Willebrand factor (vWF) type D domain - - - 0.00000000000000000001256 108.0
TLS2_k127_7346997_1 von Willebrand factor, type A K07114 - - 0.000000000000004149 90.0
TLS2_k127_7346997_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000004111 50.0
TLS2_k127_7368778_0 Large extracellular alpha-helical protein K06894 - - 0.0 1287.0
TLS2_k127_737637_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 466.0
TLS2_k127_737637_1 Restriction endonuclease - - - 0.00000000000000000000008083 107.0
TLS2_k127_7401973_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 3.3e-274 867.0
TLS2_k127_7401973_1 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000001756 177.0
TLS2_k127_7401973_2 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000001013 163.0
TLS2_k127_7428348_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1766.0
TLS2_k127_7428348_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007031 286.0
TLS2_k127_7428348_2 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000000000001435 132.0
TLS2_k127_7428348_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000001925 121.0
TLS2_k127_7428348_4 Belongs to the glycosyl hydrolase 2 family - - - 0.00000000006204 76.0
TLS2_k127_7428348_5 - - - - 0.0000002078 64.0
TLS2_k127_7428348_6 Glutathione transferase K21253,K21264,K21265 - 2.5.1.18 0.000000686 59.0
TLS2_k127_7428747_0 Belongs to the precorrin methyltransferase family K02303,K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 499.0
TLS2_k127_7428747_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002376 286.0
TLS2_k127_7428747_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000001643 219.0
TLS2_k127_7428747_3 Cytochrome C assembly protein - - - 0.00005047 47.0
TLS2_k127_7430897_0 dehydrogenase e1 component K00164 - 1.2.4.2 0.0 1115.0
TLS2_k127_7430897_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 466.0
TLS2_k127_7430897_10 Phosphoesterase (MutT - - - 0.000000000926 63.0
TLS2_k127_7430897_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 459.0
TLS2_k127_7430897_3 shikimate 3-dehydrogenase (NADP+) activity K00800,K10669 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19,2.7.1.160 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 423.0
TLS2_k127_7430897_4 Mandelate racemase muconate lactonizing enzyme K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 376.0
TLS2_k127_7430897_5 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 314.0
TLS2_k127_7430897_6 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009006 276.0
TLS2_k127_7430897_7 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000003333 216.0
TLS2_k127_7430897_8 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000007054 170.0
TLS2_k127_7430897_9 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000002188 152.0
TLS2_k127_7444565_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 363.0
TLS2_k127_7444565_1 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002651 267.0
TLS2_k127_7444565_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000006332 233.0
TLS2_k127_7444565_4 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000006811 60.0
TLS2_k127_7444565_6 Domain of unknown function (DUF1731) K07071 - - 0.0001992 49.0
TLS2_k127_7459916_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 337.0
TLS2_k127_7459916_1 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 293.0
TLS2_k127_7459916_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000121 108.0
TLS2_k127_7459916_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K00433 - 1.11.1.10 0.00000000000000005552 83.0
TLS2_k127_7459916_6 LysR substrate binding domain - - - 0.00000003353 60.0
TLS2_k127_7459916_9 E-Z type HEAT repeats - - - 0.0001627 53.0
TLS2_k127_752840_0 4-amino-4-deoxy-L-arabinose transferase activity K00728 - 2.4.1.109 0.000000000002494 78.0
TLS2_k127_757370_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 492.0
TLS2_k127_757370_1 Anaphase-promoting complex subunit 4 WD40 domain K20332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 392.0
TLS2_k127_757370_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 331.0
TLS2_k127_757370_3 AAA-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 342.0
TLS2_k127_757370_4 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000007668 254.0
TLS2_k127_795512_0 FtsX-like permease family K02004 - - 9.085e-246 783.0
TLS2_k127_795512_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 5.118e-237 745.0
TLS2_k127_795512_10 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000000000554 137.0
TLS2_k127_795512_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000003302 90.0
TLS2_k127_795512_12 Trehalose utilisation - - - 0.00000001622 66.0
TLS2_k127_795512_2 Ion channel - - - 3.725e-211 670.0
TLS2_k127_795512_3 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 3.354e-202 643.0
TLS2_k127_795512_4 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 627.0
TLS2_k127_795512_5 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 371.0
TLS2_k127_795512_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 357.0
TLS2_k127_795512_7 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 353.0
TLS2_k127_795512_8 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 306.0
TLS2_k127_795512_9 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 320.0
TLS2_k127_797838_0 AcrB/AcrD/AcrF family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 596.0
TLS2_k127_797838_1 Heavy-metal resistance - - - 0.0001077 50.0
TLS2_k127_824088_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.225e-259 807.0
TLS2_k127_824088_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 600.0
TLS2_k127_824088_10 - - - - 0.000006659 57.0
TLS2_k127_824088_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 471.0
TLS2_k127_824088_3 Putative ATP-binding cassette - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 398.0
TLS2_k127_824088_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 347.0
TLS2_k127_824088_5 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006008 268.0
TLS2_k127_824088_6 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000004591 182.0
TLS2_k127_824088_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000001446 113.0
TLS2_k127_824088_8 - - - - 0.0000000003366 65.0
TLS2_k127_824088_9 Protein of unknown function (DUF459) - - - 0.000005545 57.0
TLS2_k127_836476_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 603.0
TLS2_k127_836476_1 aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 511.0
TLS2_k127_836476_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 342.0
TLS2_k127_836476_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 310.0
TLS2_k127_836476_4 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000003267 204.0
TLS2_k127_836476_5 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000003071 178.0
TLS2_k127_836476_6 beta-propeller repeat - - - 0.00000000000000000000000000000000000001454 150.0
TLS2_k127_836476_7 Dodecin K09165 - - 0.0000000000000000000000001398 106.0
TLS2_k127_836476_8 PAP2 superfamily - - - 0.000000635 57.0
TLS2_k127_836476_9 (ABC) transporter K01990 - - 0.000006379 50.0
TLS2_k127_84285_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 1.67e-280 900.0
TLS2_k127_84285_1 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 440.0
TLS2_k127_84285_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000001746 271.0
TLS2_k127_84285_3 PFAM Type II secretion system protein E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002696 264.0
TLS2_k127_84285_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000005108 216.0
TLS2_k127_864246_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 7.335e-238 757.0
TLS2_k127_864246_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000001018 254.0
TLS2_k127_864246_2 Large extracellular alpha-helical protein K03088,K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000004328 262.0
TLS2_k127_864246_3 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000001889 205.0
TLS2_k127_864246_4 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000008702 158.0
TLS2_k127_873228_0 PFAM Aldo keto reductase family K17743 - 1.1.1.307 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 456.0
TLS2_k127_873228_1 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000242 227.0
TLS2_k127_873228_2 Manganese containing catalase K07217 - - 0.000000000000000000000000000001505 123.0
TLS2_k127_873228_3 Prokaryotic N-terminal methylation motif - - - 0.00000000000005094 82.0
TLS2_k127_873228_4 Belongs to the catalase family K03781 - 1.11.1.6 0.000000001411 58.0
TLS2_k127_878639_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 512.0
TLS2_k127_878639_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 400.0
TLS2_k127_878639_2 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 385.0
TLS2_k127_878639_3 reverse transcriptase K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 384.0
TLS2_k127_878639_4 TIGRFAM tripartite ATP-independent periplasmic transporter solute receptor, DctP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008171 264.0
TLS2_k127_878639_5 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001539 258.0
TLS2_k127_878639_6 - - - - 0.000000000000000000000000000000000000000000001345 170.0
TLS2_k127_878639_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000003745 121.0
TLS2_k127_91833_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 491.0
TLS2_k127_91833_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 369.0
TLS2_k127_91833_2 protein with a C-terminal OMP (outer membrane protein) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 361.0
TLS2_k127_91833_3 ig-like, plexins, transcription factors - - - 0.000000000000000000000000000000000000000000000005365 199.0
TLS2_k127_91833_4 cellulose binding - - - 0.0000000000000000000000001926 123.0
TLS2_k127_91833_5 Phosphate acyltransferases - - - 0.00000000001096 68.0
TLS2_k127_91833_6 beta-galactosidase activity - - - 0.00000003386 61.0
TLS2_k127_92831_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 452.0
TLS2_k127_92831_1 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000003619 211.0
TLS2_k127_933175_0 Ribosomal protein S1-like RNA-binding domain K02945 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 518.0
TLS2_k127_933175_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 326.0
TLS2_k127_933175_2 isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001185 278.0
TLS2_k127_933175_3 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004199 274.0
TLS2_k127_933175_4 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002221 255.0
TLS2_k127_933175_5 Histidine kinase K07637,K07638,K07717 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000001888 209.0
TLS2_k127_933175_6 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000001704 197.0
TLS2_k127_933175_8 - - - - 0.000007146 49.0
TLS2_k127_936558_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 507.0
TLS2_k127_936558_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 375.0
TLS2_k127_936558_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000002323 221.0
TLS2_k127_936558_3 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000000000000000000000000000000000000000000001212 208.0
TLS2_k127_936558_4 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000002814 175.0
TLS2_k127_947736_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1090.0
TLS2_k127_947736_1 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000008221 157.0
TLS2_k127_947736_2 PFAM Diacylglycerol kinase, catalytic - - - 0.000000000000000000000001775 110.0
TLS2_k127_947736_3 RDD family - - - 0.00000000000001087 75.0
TLS2_k127_967719_0 Protein of unknown function (DUF455) - - - 3.842e-206 651.0
TLS2_k127_967719_1 Domain of unknown function (DUF4912) K09942 - - 0.0000000000000000000000000000000000002389 157.0
TLS2_k127_967719_2 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000332 148.0
TLS2_k127_967719_3 Lamin Tail Domain - - - 0.0000000000000000000000000000001841 130.0
TLS2_k127_967719_4 general secretion pathway protein K02456 - - 0.00000000000000001968 92.0
TLS2_k127_967719_5 - - - - 0.0000000000005001 74.0
TLS2_k127_967719_6 M6 family metalloprotease domain protein - - - 0.00000000001221 78.0
TLS2_k127_967719_8 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000101 63.0
TLS2_k127_994620_0 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 352.0
TLS2_k127_994620_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000001148 195.0
TLS2_k127_994620_2 general secretion pathway protein K02456 - - 0.00000000004946 75.0
TLS2_k127_994620_3 PFAM PepSY-associated TM helix domain protein K09939 - - 0.00000005014 61.0