TLS2_k127_100125_0
Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K02379
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974
342.0
View
TLS2_k127_100125_1
Rhomboid family
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218
309.0
View
TLS2_k127_100125_2
Protein conserved in bacteria
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000001307
269.0
View
TLS2_k127_100125_3
von Willebrand factor, type A
-
-
-
0.000000000000000000000000000000000000000000000000000002879
199.0
View
TLS2_k127_100125_4
(twin-arginine translocation) pathway signal
-
-
-
0.00000000000000000000000000001019
133.0
View
TLS2_k127_100157_0
SAICAR synthetase
K01923
-
6.3.2.6
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139
447.0
View
TLS2_k127_100157_1
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K01952
-
6.3.5.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403
333.0
View
TLS2_k127_100157_2
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K01952
-
6.3.5.3
0.00000000000000000000000000005333
117.0
View
TLS2_k127_100157_3
Domain of unknown function (DUF1476)
-
-
-
0.0000000000003615
72.0
View
TLS2_k127_1006922_0
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K00822
-
2.6.1.18
1.241e-237
747.0
View
TLS2_k127_1006922_1
Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
K02052,K11072,K11076
-
3.6.3.31
2.511e-197
634.0
View
TLS2_k127_1006922_2
Aldehyde dehydrogenase family
K00140
-
1.2.1.18,1.2.1.27
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055
503.0
View
TLS2_k127_1006922_3
Binding-protein-dependent transport system inner membrane component
K11070
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143
431.0
View
TLS2_k127_1006922_4
putrescine
K11071
-
-
0.0000000000000000000000000000000000000000000000000000000004147
202.0
View
TLS2_k127_1007686_0
it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins
K02314
-
3.6.4.12
1.067e-211
667.0
View
TLS2_k127_1007686_1
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K04485
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395
549.0
View
TLS2_k127_1007686_2
Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K01775
-
5.1.1.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117
356.0
View
TLS2_k127_1007686_3
binds to the 23S rRNA
K02939
GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000000000000000000000000000000000000000000000005866
239.0
View
TLS2_k127_1007686_4
membrane
-
-
-
0.00000000000000000000000000000000000000000000000000000000000008734
225.0
View
TLS2_k127_101377_0
Catalyzes the NAD( )-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non- methylotrophic organisms
K00122
-
1.17.1.9
1.674e-222
698.0
View
TLS2_k127_101377_1
PFAM regulatory protein LysR
-
-
-
0.000000000000000000000000001711
115.0
View
TLS2_k127_101377_2
Amidase
K02433
-
6.3.5.6,6.3.5.7
0.00000000000000000001318
91.0
View
TLS2_k127_1015040_0
Permease MlaE
K02066
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155
456.0
View
TLS2_k127_1015040_1
ATPases associated with a variety of cellular activities
K02065
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878
379.0
View
TLS2_k127_1015040_2
ABC-type transport auxiliary lipoprotein component
K02067
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499
336.0
View
TLS2_k127_1017085_0
Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K02112
-
3.6.3.14
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702
327.0
View
TLS2_k127_1017085_1
Divergent polysaccharide deacetylase
K09798
-
-
0.000000000000000000000000000000000000000000000000000000000000004043
226.0
View
TLS2_k127_1017085_2
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage
K08311
-
-
0.0000000000000000000000000000000000000000000000000000000000002131
217.0
View
TLS2_k127_1017085_3
Produces ATP from ADP in the presence of a proton gradient across the membrane
K02113,K02114
GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600
-
0.000000000000000000000000000000000000002972
149.0
View
TLS2_k127_1026479_0
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K02469
-
5.99.1.3
0.0
1302.0
View
TLS2_k127_1026479_1
PRC-barrel domain
-
-
-
0.0000000000000000008024
97.0
View
TLS2_k127_1026479_2
PFAM Acyltransferase
-
-
-
0.0002096
46.0
View
TLS2_k127_1039920_0
Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
K07712
-
-
5.828e-200
628.0
View
TLS2_k127_1039920_1
His Kinase A (phospho-acceptor) domain
K07708
-
2.7.13.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589
513.0
View
TLS2_k127_1039920_2
Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)
K01770,K12506
-
2.7.7.60,4.6.1.12
0.00000000000000000003178
93.0
View
TLS2_k127_1045750_0
Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
K21071
-
2.7.1.11,2.7.1.90
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002
390.0
View
TLS2_k127_1045750_1
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
K00797
-
2.5.1.16
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333
340.0
View
TLS2_k127_1045750_2
S-adenosylmethionine decarboxylase
K00797,K01611
-
2.5.1.16,4.1.1.50
0.00000000000000000000000000000000000000000000000000000000000000000000000136
248.0
View
TLS2_k127_1045750_3
Phosphodiester glycosidase
-
-
-
0.000000000000000000000000000000000000000001325
159.0
View
TLS2_k127_1058868_0
PAS fold
K07716
-
2.7.13.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338
621.0
View
TLS2_k127_1058868_1
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
K00982
GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090
2.7.7.42,2.7.7.89
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011
555.0
View
TLS2_k127_1058868_2
Putative diguanylate phosphodiesterase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907
425.0
View
TLS2_k127_1091788_0
Belongs to the DEAD box helicase family
K03732,K11927
-
3.6.4.13
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323
493.0
View
TLS2_k127_1091788_1
Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
K02622
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885
373.0
View
TLS2_k127_1091788_2
Isoprenylcysteine carboxyl methyltransferase (ICMT) family
-
-
-
0.0000000000000000000000000005946
119.0
View
TLS2_k127_1102012_0
chorismate binding enzyme
K01665,K03342
-
2.6.1.85,4.1.3.38
4.797e-196
631.0
View
TLS2_k127_1102012_1
cheY-homologous receiver domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446
354.0
View
TLS2_k127_1102012_2
Sigma-70, region 4
K03088
-
-
0.00000000000000000000000000000000000000000000000000000000000000001651
228.0
View
TLS2_k127_1102012_3
TIGRFAM formylmethanofuran dehydrogenase subunit C
K00202
-
1.2.7.12
0.000000000000000000000000000000000000000001623
162.0
View
TLS2_k127_1102012_4
Protein of unknown function (DUF3309)
-
-
-
0.0000000000000000002814
88.0
View
TLS2_k127_1102012_5
-
-
-
-
0.00000003504
59.0
View
TLS2_k127_1102012_6
CsbD-like
-
-
-
0.0000002077
52.0
View
TLS2_k127_1110182_0
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K00789
-
2.5.1.6
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155
571.0
View
TLS2_k127_1110182_1
Participates in both transcription termination and antitermination
K02600
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751
469.0
View
TLS2_k127_1110182_2
Putative methyltransferase
K03439
GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234
2.1.1.33
0.0000000000000000000000000000000000000000000000000000000000002959
219.0
View
TLS2_k127_1110182_3
Required for maturation of 30S ribosomal subunits
K09748
GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576
-
0.00000000000000000000000000000000000000000000000000000000001242
212.0
View
TLS2_k127_1110182_4
Sulfite exporter TauE/SafE
K07090
-
-
0.00000000000000000000000000000000000000000001796
166.0
View
TLS2_k127_1110182_5
Transcriptional regulator
-
-
-
0.000000000000000000000000000000000000000004011
160.0
View
TLS2_k127_1110182_6
Sulfite exporter TauE/SafE
K07090
-
-
0.0000000000000000000000000000009527
123.0
View
TLS2_k127_1116949_0
Methylmalonyl-CoA mutase
K14447
-
5.4.99.63
8.902e-308
956.0
View
TLS2_k127_1116949_1
reductase
K00001,K14446
-
1.1.1.1,1.3.1.85
4.95e-243
754.0
View
TLS2_k127_1119661_0
Belongs to the PEP-utilizing enzyme family
K08484
-
2.7.3.9
1.571e-285
895.0
View
TLS2_k127_1119661_1
Belongs to the aspartokinase family
K00928
GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
2.7.2.4
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066
355.0
View
TLS2_k127_113262_0
GTP-binding protein TypA
K06207
GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876
525.0
View
TLS2_k127_113262_1
Tetratricopeptide repeats
-
-
-
0.00001773
54.0
View
TLS2_k127_1133767_0
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
K01419
-
3.4.25.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001438
276.0
View
TLS2_k127_1133767_1
this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
K03667
-
-
0.0000000000000000000001823
96.0
View
TLS2_k127_1136290_0
Methylmalonyl-CoA mutase
K01847
-
5.4.99.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301
626.0
View
TLS2_k127_1136290_1
Bacterial protein of unknown function (DUF853)
K06915
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427
490.0
View
TLS2_k127_1136290_2
Methylmalonyl-CoA mutase
K01847
-
5.4.99.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000005156
261.0
View
TLS2_k127_1144870_0
DEAD/H associated
K03724
-
-
0.0
1902.0
View
TLS2_k127_1144870_1
FMN binding
-
-
-
0.000000000000000000000000000000000000000000000000000000002576
208.0
View
TLS2_k127_1144870_2
Belongs to the short-chain dehydrogenases reductases (SDR) family
-
-
-
0.00000000002257
67.0
View
TLS2_k127_1158567_0
Methionine biosynthesis protein MetW
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004863
289.0
View
TLS2_k127_1158567_1
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K00684
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096
2.3.2.6
0.000000000000000000000000000000000000000000000000000000000364
207.0
View
TLS2_k127_1158567_2
NADH ubiquinone oxidoreductase subunit NDUFA12
K00356
-
1.6.99.3
0.00000000000000000000000000000000000000000001526
169.0
View
TLS2_k127_1158567_3
cheY-homologous receiver domain
K03413
-
-
0.000000000000000000000006197
108.0
View
TLS2_k127_1172812_0
protein histidine kinase activity
K13924
-
2.1.1.80,3.1.1.61
0.0000000000000000000000000000000006972
145.0
View
TLS2_k127_1172812_1
Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
K01679
GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350
4.2.1.2
0.000000000000000000000198
100.0
View
TLS2_k127_1178658_0
d-alanyl-d-alanine carboxypeptidase
K07259
-
3.4.16.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238
570.0
View
TLS2_k127_1178658_1
Calcineurin-like phosphoesterase superfamily domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352
374.0
View
TLS2_k127_1178658_2
glutamine amidotransferase
K01951
-
6.3.5.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001204
301.0
View
TLS2_k127_1178658_3
PFAM peptidase, membrane zinc metallopeptidase
K06973
-
-
0.0000000000000000000000000000000000000000000000000000000000000007729
227.0
View
TLS2_k127_1178658_4
Putative neutral zinc metallopeptidase
K06973
-
-
0.000002321
50.0
View
TLS2_k127_1197774_0
Histidine kinase
-
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858
598.0
View
TLS2_k127_1197774_1
Threonylcarbamoyl adenosine biosynthesis protein TsaE
K07102
-
2.7.1.221
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163
520.0
View
TLS2_k127_1197774_2
Nucleotidyl transferase
K00966,K00992
-
2.7.7.13,2.7.7.99
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537
297.0
View
TLS2_k127_1197774_3
PD-(D/E)XK nuclease superfamily
K16899
-
3.6.4.12
0.000000000000000000000000000000000000000000000000000000000000000000000000002897
265.0
View
TLS2_k127_1197774_4
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K01251
-
3.3.1.1
0.0000000000000000000000000000000000000000111
154.0
View
TLS2_k127_1200161_0
Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K00864
GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615
2.7.1.30
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333
320.0
View
TLS2_k127_1200161_1
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K00684
-
2.3.2.6
0.0000000000000000000000000000000000000000000000000000000001829
214.0
View
TLS2_k127_1200161_2
cyclic nucleotide-binding
K03321
-
-
0.000000000000000000000000000001194
133.0
View
TLS2_k127_1200161_3
Cyclic nucleotide-monophosphate binding domain
-
-
-
0.00000000000000000000000000002447
121.0
View
TLS2_k127_1200161_4
Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K00864
GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615
2.7.1.30
0.00000000000000000000000002789
114.0
View
TLS2_k127_1200161_5
Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K00864
GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615
2.7.1.30
0.000000000000000000000001245
107.0
View
TLS2_k127_1200161_6
Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K00864
GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615
2.7.1.30
0.0000000000000000006868
93.0
View
TLS2_k127_1200161_7
CutA1 divalent ion tolerance protein
K03926
-
-
0.00000001262
56.0
View
TLS2_k127_1202544_0
Tryptophanyl-tRNA synthetase
K01867
-
6.1.1.2
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204
518.0
View
TLS2_k127_1202544_1
Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
K03980
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284
512.0
View
TLS2_k127_1202544_2
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K00990
GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141
2.7.7.59
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358
405.0
View
TLS2_k127_121138_0
Protein of unknown function (DUF3570)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425
325.0
View
TLS2_k127_121138_1
Mediates influx of magnesium ions
K03284
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000009387
263.0
View
TLS2_k127_121138_2
Transglycosylase SLT domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000369
239.0
View
TLS2_k127_121138_3
Cytochrome P460
-
-
-
0.00000000000000000000000000000000000000000001796
166.0
View
TLS2_k127_1223174_0
HlyD family secretion protein
K03585
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132
353.0
View
TLS2_k127_1223174_1
alcohol dehydrogenase
K13953
-
1.1.1.1
0.000000000000000000000000000000000000000000000000000000000000000000000002866
246.0
View
TLS2_k127_1256693_0
Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K00946
-
2.7.4.16
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001949
286.0
View
TLS2_k127_1256693_1
NusB family
K03625
-
-
0.00000000000000000000000000000000000000000000000000001804
194.0
View
TLS2_k127_1256693_2
Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
K00794
-
2.5.1.78
0.00000000000000000000000003099
110.0
View
TLS2_k127_1270639_0
Predicted membrane protein (DUF2254)
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227
362.0
View
TLS2_k127_1270639_1
Adenylyl- / guanylyl cyclase, catalytic domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000408
215.0
View
TLS2_k127_1270639_2
Helix-turn-helix
K21498
-
-
0.0000000000000000000000000000000000000006704
151.0
View
TLS2_k127_1270639_3
Plasmid maintenance system killer
-
-
-
0.000000000000000000000000005092
111.0
View
TLS2_k127_1274356_0
Carboxyl transferase domain
K01966
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575
2.1.3.15,6.4.1.3
4.135e-247
766.0
View
TLS2_k127_1274356_1
RNA pseudouridylate synthase
K06179
GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360
5.4.99.24
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252
444.0
View
TLS2_k127_1274356_2
ATP12 chaperone protein
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000004798
263.0
View
TLS2_k127_1274356_3
Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K06199
GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425
-
0.00000000000000000000000000000000000000000000000002662
182.0
View
TLS2_k127_1274356_4
Low affinity iron permease
-
-
-
0.00000000000000000000000000000000000000000003427
164.0
View
TLS2_k127_1274356_5
Kazal type serine protease inhibitors
-
-
-
0.0000000000000000000003987
100.0
View
TLS2_k127_1274356_6
Uncharacterized ACR, COG1993
K09137
-
-
0.000000000000000005508
91.0
View
TLS2_k127_1274356_7
Uncharacterized ACR, COG1993
K09137
-
-
0.00000002463
58.0
View
TLS2_k127_1278627_0
Outer membrane efflux protein
K12340
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562
301.0
View
TLS2_k127_1278627_1
Ribosomal RNA adenine dimethylase
K00573
-
2.1.1.77
0.000000000000000000000000000000000000000000000000000000002205
208.0
View
TLS2_k127_1278627_2
transferase activity, transferring glycosyl groups
-
-
-
0.000002178
49.0
View
TLS2_k127_1284718_0
Belongs to the ribulose-phosphate 3-epimerase family
K01783
GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575
5.1.3.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691
328.0
View
TLS2_k127_1284718_1
Belongs to the phosphoglycerate kinase family
K00927
-
2.7.2.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232
322.0
View
TLS2_k127_1284718_2
Cytochrome C biogenesis protein transmembrane region
K06196
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000873
290.0
View
TLS2_k127_1284718_3
PFAM Phosphomethylpyrimidine kinase
K00941
-
2.7.1.49,2.7.4.7
0.0000000000000000000000000000000000000000000000000009334
188.0
View
TLS2_k127_1288219_0
argininosuccinate lyase
K01755
GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
4.3.2.1
1.346e-207
655.0
View
TLS2_k127_1288219_1
Bacterial protein of unknown function (DUF924)
-
-
-
0.00000000000000000000000000000000000000000000000000000003704
204.0
View
TLS2_k127_1288219_2
Thioredoxin-like
-
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
-
0.00000000000000000000000000000000000000000000000005675
187.0
View
TLS2_k127_1288219_3
YARHG
-
-
-
0.00000000000000000006145
100.0
View
TLS2_k127_1320753_0
Allophanate hydrolase subunit 2
K01941
-
6.3.4.6
0.0
1125.0
View
TLS2_k127_1320753_1
Allophanate hydrolase subunit 2
K01941
-
6.3.4.6
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108
441.0
View
TLS2_k127_1320753_2
Domain of unknown function (DUF1989)
K09967
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624
405.0
View
TLS2_k127_1320753_3
Amidase
K01457
-
3.5.1.54
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951
406.0
View
TLS2_k127_1320753_4
Domain of unknown function (DUF1989)
K09967
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466
376.0
View
TLS2_k127_1320753_5
Amidase
K01457
-
3.5.1.54
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653
357.0
View
TLS2_k127_1320753_6
glutamine synthetase
K01915
-
6.3.1.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116
300.0
View
TLS2_k127_1320753_7
Allophanate hydrolase subunit 2
K01941
-
6.3.4.6
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842
295.0
View
TLS2_k127_1320753_8
NikR C terminal nickel binding domain
K07722
-
-
0.000000000000000000000000000000000000000000000000000004046
194.0
View
TLS2_k127_1320753_9
Patatin-like phospholipase
-
-
-
0.0000000000000000000000007017
106.0
View
TLS2_k127_1370679_0
Major Facilitator Superfamily
-
GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858
582.0
View
TLS2_k127_1370679_1
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
K07755
-
2.1.1.137
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279
467.0
View
TLS2_k127_1370679_2
Ppx/GppA phosphatase family
K01524
-
3.6.1.11,3.6.1.40
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372
431.0
View
TLS2_k127_1370679_3
FtsJ-like methyltransferase
K02427
-
2.1.1.166
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000125
284.0
View
TLS2_k127_1379118_0
TIGRFAM phage
-
-
-
0.000000000000000000000000000000000000000000000000000000000000002083
224.0
View
TLS2_k127_1379118_1
DNA methylase
-
-
-
0.0000000000000000000000000000000000006916
143.0
View
TLS2_k127_1379118_2
Histidine kinase
-
-
-
0.00000000000000000000000001501
119.0
View
TLS2_k127_1379118_3
-
-
-
-
0.000000000000000009399
90.0
View
TLS2_k127_1379118_4
Terminase RNaseH-like domain
-
-
-
0.00000000000000047
85.0
View
TLS2_k127_1379118_5
Bacterial sugar transferase
-
-
-
0.00000001594
59.0
View
TLS2_k127_1397106_0
Transcriptional regulatory protein, C terminal
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276
374.0
View
TLS2_k127_1397106_1
L,D-transpeptidase catalytic domain
-
-
-
0.000000000000000000000000000000000000000000000000006422
186.0
View
TLS2_k127_1397106_2
Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K06997
GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363
-
0.0000000000408
63.0
View
TLS2_k127_1406201_0
ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
K03686
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458
567.0
View
TLS2_k127_1406201_1
Heat shock 70 kDa protein
K04043
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186
310.0
View
TLS2_k127_141618_0
Sugar (and other) transporter
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769
498.0
View
TLS2_k127_141618_1
PFAM secretion protein HlyD family protein
K03543,K15549
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000001164
272.0
View
TLS2_k127_141618_2
Belongs to the short-chain dehydrogenases reductases (SDR) family
K07124
-
-
0.000000000000000000000000000000000000000000000000000000000000000000002764
246.0
View
TLS2_k127_1445157_0
Patatin-like phospholipase
K07001
GO:0003674,GO:0003824,GO:0016787
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434
379.0
View
TLS2_k127_1445157_1
GTP cyclohydrolase I
K01495
-
3.5.4.16
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005464
289.0
View
TLS2_k127_1445157_2
COG0822 NifU homolog involved in Fe-S cluster formation
-
-
-
0.0000000000000000000000000000000000000000000000000000001797
198.0
View
TLS2_k127_1445157_3
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K01496,K11755
-
3.5.4.19,3.6.1.31
0.000000000000000000000000000000000000000000000000000001091
196.0
View
TLS2_k127_1445157_4
Rhomboid family
-
-
-
0.000000000000000000000000000000000000000000000000003035
191.0
View
TLS2_k127_1445157_5
Domain in cystathionine beta-synthase and other proteins.
-
-
-
0.0000000000000000000000000000000000004864
153.0
View
TLS2_k127_1445157_6
Could be involved in insertion of integral membrane proteins into the membrane
K08998
-
-
0.00000000000000000000000000000000002078
141.0
View
TLS2_k127_1445157_7
Putative restriction endonuclease
-
-
-
0.00004633
46.0
View
TLS2_k127_144919_0
Histidine kinase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832
347.0
View
TLS2_k127_144919_1
PFAM Diacylglycerol kinase catalytic
-
-
-
0.00000000000000000000000000000000000000000000000000002737
199.0
View
TLS2_k127_144919_2
Histidine kinase
-
-
-
0.0000000000000000000000000003263
119.0
View
TLS2_k127_144919_3
CsbD-like
-
-
-
0.000000000000000000000000001947
113.0
View
TLS2_k127_144919_4
SelR domain
K07305
-
1.8.4.12
0.000000000000002593
79.0
View
TLS2_k127_144919_5
UPF0391 membrane protein
-
-
-
0.00000000002306
65.0
View
TLS2_k127_145464_0
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K02335
GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576
2.7.7.7
0.0
1159.0
View
TLS2_k127_145464_1
Pyridine nucleotide-disulphide oxidoreductase
K03885
-
1.6.99.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584
469.0
View
TLS2_k127_145464_2
-
-
-
-
0.00000000000000000000000000000000002565
137.0
View
TLS2_k127_1459246_0
-
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727
437.0
View
TLS2_k127_1459246_2
Catalyzes the synthesis of GMP from XMP
K01951
GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659
6.3.5.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009035
278.0
View
TLS2_k127_1459246_3
Protein of unknown function (DUF3108)
-
-
-
0.00000000000146
76.0
View
TLS2_k127_146992_0
Involved in the TonB-independent uptake of proteins
K03641
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348
353.0
View
TLS2_k127_146992_1
MotA/TolQ/ExbB proton channel family
K03562
GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001707
293.0
View
TLS2_k127_146992_2
Cell division and transport-associated protein TolA
K03646
-
-
0.00000000000000000000000000000000000000008518
162.0
View
TLS2_k127_146992_3
Biopolymer transport protein
K03559,K03560
-
-
0.0000000000000000000000000000000001084
139.0
View
TLS2_k127_1484259_0
Tellurite resistance protein TerB
K05801
-
-
0.0000000000000000000000000000000000000000000000000000000000000000006108
241.0
View
TLS2_k127_1484259_1
Permease family
K06901
-
-
0.0000000000000000000000000000000000000000000000000000002239
198.0
View
TLS2_k127_1497134_0
NADH-quinone oxidoreductase chain
K00342
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
1.6.5.3
3.552e-238
746.0
View
TLS2_k127_1497134_1
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K00343
-
1.6.5.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002369
288.0
View
TLS2_k127_1497134_2
NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
K00341
-
1.6.5.3
0.0000000000000000000000000000000000000000000000000000000004117
205.0
View
TLS2_k127_1501921_0
Belongs to the CDS family
K00981
-
2.7.7.41
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463
379.0
View
TLS2_k127_1501921_1
Phosphate acyltransferases
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000006342
233.0
View
TLS2_k127_1501921_2
integral membrane protein
-
-
-
0.0000000000000000000000000000000001276
140.0
View
TLS2_k127_151131_0
PFAM acyl-CoA dehydrogenase
K11731,K14448
-
1.3.8.12
3.336e-255
797.0
View
TLS2_k127_151131_1
Electron transfer flavoprotein
K03521
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519
383.0
View
TLS2_k127_151131_2
Belongs to the short-chain dehydrogenases reductases (SDR) family
-
GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812
327.0
View
TLS2_k127_151131_3
Cobalamin adenosyltransferase
K00798
-
2.5.1.17
0.00000000000000000000000000000000000000000000000000000000000000000000000000000006917
271.0
View
TLS2_k127_151131_4
Rhomboid family
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000001349
274.0
View
TLS2_k127_151131_5
Electron transfer flavoprotein
K03522
-
-
0.000000000000000000000000000000000000000000001335
168.0
View
TLS2_k127_151131_6
PFAM TspO MBR family
K05770
-
-
0.000000000000000000000000000000000000003053
151.0
View
TLS2_k127_151131_7
Hypoxia induced protein conserved region
-
-
-
0.00000000000006003
83.0
View
TLS2_k127_1538119_0
Transposase DDE domain group 1
-
-
-
4.799e-223
698.0
View
TLS2_k127_1538119_1
Adenylosuccinate synthetase
K01939
-
6.3.4.4
0.000004772
53.0
View
TLS2_k127_1540090_0
Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K06168
-
2.8.4.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693
484.0
View
TLS2_k127_1540090_1
Transfers the fatty acyl group on membrane lipoproteins
K03820
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735
494.0
View
TLS2_k127_1540090_2
PhoH-like protein
K06217
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787
397.0
View
TLS2_k127_1540090_3
Transporter associated domain
K06189
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789
323.0
View
TLS2_k127_1540090_4
Helix-turn-helix XRE-family like proteins
-
-
-
0.000000000000000000000000000000000000000000000000000001096
195.0
View
TLS2_k127_1540090_5
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K07042
-
-
0.000000000000000000000000000000000001171
147.0
View
TLS2_k127_1540090_6
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K00789
-
2.5.1.6
0.0000000000000000001653
89.0
View
TLS2_k127_154297_0
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K00600
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
2.1.2.1
9.348e-222
693.0
View
TLS2_k127_154297_1
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K02858,K14652
-
3.5.4.25,4.1.99.12
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189
499.0
View
TLS2_k127_154297_2
RibD C-terminal domain
K11752
-
1.1.1.193,3.5.4.26
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741
338.0
View
TLS2_k127_154297_3
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K07738
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000006675
254.0
View
TLS2_k127_154297_4
riboflavin synthase, alpha
K00793
GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
2.5.1.9
0.00000000000000000000000000000000000000000000000000000000000000002295
230.0
View
TLS2_k127_154297_5
Sulfite exporter TauE/SafE
K07090
-
-
0.0000000000000000000000000000000000000001727
156.0
View
TLS2_k127_154297_6
Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
K00794
-
2.5.1.78
0.000000000000000000001903
99.0
View
TLS2_k127_154297_7
Sulfite exporter TauE/SafE
K07090
-
-
0.0000000002169
68.0
View
TLS2_k127_1556597_0
PFAM Aminotransferase class IV
K00824
-
2.6.1.21
0.0000000000000000000000000000000000000000000000000000000000000000000000000000004462
270.0
View
TLS2_k127_1556597_1
Domain of unknown function (DUF892)
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000001702
238.0
View
TLS2_k127_1556597_2
COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000007736
239.0
View
TLS2_k127_1556597_3
-
-
-
-
0.000003042
59.0
View
TLS2_k127_15854_0
Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K01735,K13829
-
2.7.1.71,4.2.3.4
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756
420.0
View
TLS2_k127_15854_1
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K00891
GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615
2.7.1.71
0.00000000000000000000000000000000000000000000000000000000000000000006076
238.0
View
TLS2_k127_1754758_0
TrkA-N domain
-
-
-
4.879e-214
678.0
View
TLS2_k127_1754758_1
glycoside hydrolase family 25
K07273
-
-
0.000000000000000000000000000000000000006103
150.0
View
TLS2_k127_1754758_2
Protein of unknown function (DUF2852)
-
-
-
0.00000000000000000000000000000000000004215
148.0
View
TLS2_k127_1766424_0
Belongs to the LOG family
K06966
-
3.2.2.10
0.00000000000000000000000000000000000000000000000000000000000000000000000002417
258.0
View
TLS2_k127_1766424_1
protein containing LysM domain
-
-
-
0.000000000000000000000000000000000566
146.0
View
TLS2_k127_1766424_2
protein containing LysM domain
-
-
-
0.000000149
59.0
View
TLS2_k127_1779890_0
DEAD-like helicases superfamily
K11927
-
3.6.4.13
0.000000000000000000000000000000000000000000000000000000000000000000004155
241.0
View
TLS2_k127_1779890_1
long-chain fatty acid transport protein
-
-
-
0.0000000000000000000000000000000000000000000000000000000000021
219.0
View
TLS2_k127_1779890_2
-
-
-
-
0.0000000000000000000000003454
106.0
View
TLS2_k127_1779890_3
-
-
-
-
0.00000002364
56.0
View
TLS2_k127_179424_0
Universal stress protein family
-
-
-
0.000000000000000000000000000000000000000000000000000000118
199.0
View
TLS2_k127_179424_1
lipopolysaccharide transport
K09774
-
-
0.000000000000000000000000000000000000000000001676
175.0
View
TLS2_k127_1843459_0
Histidine kinase
-
-
-
0.0000000000000000000000000000000000000000000000007263
187.0
View
TLS2_k127_1843459_1
Phasin protein
-
-
-
0.000004126
54.0
View
TLS2_k127_186676_0
glutamine synthetase
K01915
-
6.3.1.2
5.574e-195
614.0
View
TLS2_k127_186676_1
Belongs to the aldehyde dehydrogenase family
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006822
285.0
View
TLS2_k127_1878498_0
thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
K02945
-
-
4.997e-285
885.0
View
TLS2_k127_1878498_1
The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
K01696
-
4.2.1.20
3.905e-226
704.0
View
TLS2_k127_1878498_2
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
K01695
-
4.2.1.20
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122
344.0
View
TLS2_k127_1878498_3
signal peptide peptidase SppA, 36K type
K04773
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444
310.0
View
TLS2_k127_1878498_4
Cytidylate kinase
K00945
GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605
2.7.4.25
0.0000000000000000000000000000000000000000000000000000000000000002208
226.0
View
TLS2_k127_1878498_5
Belongs to the TrpF family
K01817
-
5.3.1.24
0.0000000000000000000000000000000000000000000000000000000000000002641
228.0
View
TLS2_k127_1878498_6
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
K05788
GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141
-
0.000000000000000000000000000000000000000000005972
164.0
View
TLS2_k127_1878498_7
Pfam:DUF1049
-
-
-
0.00000000000000000002575
94.0
View
TLS2_k127_1881866_0
Pyruvate kinase, alpha/beta domain
K00873
-
2.7.1.40
1.19e-199
633.0
View
TLS2_k127_1881866_1
Protein of unknown function (DUF1036)
-
-
-
0.00000000000000000000000000000000000000000000000000000000000242
212.0
View
TLS2_k127_1881866_2
COG0457 FOG TPR repeat
-
-
-
0.000000000000000000000000000000000617
141.0
View
TLS2_k127_1881866_3
N-formylglutamate amidohydrolase
-
-
-
0.00000000000005415
74.0
View
TLS2_k127_1881866_4
Ribosomal protein L36
K02919
-
-
0.0000000000001675
72.0
View
TLS2_k127_1891656_0
Domain of unknown function (DUF3458_C) ARM repeats
K01256
GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564
3.4.11.2
2.895e-245
773.0
View
TLS2_k127_1896753_0
Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384
539.0
View
TLS2_k127_1896753_1
Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
K03455
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766
510.0
View
TLS2_k127_1916196_0
that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K03555
GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937
536.0
View
TLS2_k127_1916196_1
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K00990
GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141
2.7.7.59
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838
459.0
View
TLS2_k127_1918141_0
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K01895
-
6.2.1.1
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815
552.0
View
TLS2_k127_1918141_1
Belongs to the globin family
K05916
-
1.14.12.17
0.000000000000003023
83.0
View
TLS2_k127_1920352_0
Pfam:DUF59
-
-
-
0.000000000000000000000000000000000000000000000000000006311
196.0
View
TLS2_k127_1920352_1
Iron-sulphur cluster biosynthesis
K13628
GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
-
0.0000000000000000000000000000000000000000000005666
169.0
View
TLS2_k127_1920352_2
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K11717
-
2.8.1.7,4.4.1.16
0.00000000000000000000000000000004652
125.0
View
TLS2_k127_1920352_3
Belongs to the DEAD box helicase family
K03732,K11927
-
3.6.4.13
0.000000000000000000000001456
109.0
View
TLS2_k127_1932131_0
elongator protein 3 miab nifb
-
-
-
4.252e-237
746.0
View
TLS2_k127_1932131_1
Protein of unknown function (DUF1622)
-
-
-
0.00000000000006329
73.0
View
TLS2_k127_1934802_0
Sulfate tungstate uptake family ABC transporter, periplasmic substrate-binding protein
K05772
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335
384.0
View
TLS2_k127_1934802_1
ABC transporter
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001113
279.0
View
TLS2_k127_1934802_2
von Willebrand factor, type A
-
-
-
0.00000000000000000000000000000000002836
143.0
View
TLS2_k127_1934802_3
ABC-type tungstate transport system, periplasmic component
K05773
-
-
0.0000000009855
60.0
View
TLS2_k127_193588_0
Belongs to the universal ribosomal protein uS2 family
K02967
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504
392.0
View
TLS2_k127_193588_1
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K02357
GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805
383.0
View
TLS2_k127_193588_2
DNA polymerase alpha chain like domain
K02337
GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496
2.7.7.7
0.00000000000000000000000000000000000000000000000000000005274
204.0
View
TLS2_k127_1966882_0
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K00615
-
2.2.1.1
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368
456.0
View
TLS2_k127_1966882_1
Phosphoribulokinase / Uridine kinase family
K00855
-
2.7.1.19
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401
405.0
View
TLS2_k127_1966882_2
Permease
K02033
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643
380.0
View
TLS2_k127_1966882_3
Bacterial fructose-1,6-bisphosphatase, glpX-encoded
K02446
-
3.1.3.11
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651
339.0
View
TLS2_k127_1966882_4
(ABC) transporter, permease
K02034
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401
322.0
View
TLS2_k127_196768_0
Cytochrome c
-
-
-
2.09e-231
734.0
View
TLS2_k127_1983440_0
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components
K03110
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593
394.0
View
TLS2_k127_1983440_1
probably involved in intracellular septation
K06190
-
-
0.0000000000000000000000000000000000000000000000000000000000002997
217.0
View
TLS2_k127_1986506_0
Periplasmic binding protein
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002
343.0
View
TLS2_k127_1986506_1
Bacterial periplasmic substrate-binding proteins
-
-
-
0.000000000000000000000000000000000000000000000002487
179.0
View
TLS2_k127_1986506_2
biosynthesis protein E
K06139
-
-
0.00000000000000000000000000000000000000000001733
164.0
View
TLS2_k127_1986506_3
integral membrane protein
-
-
-
0.00000000001108
74.0
View
TLS2_k127_1998305_0
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047
533.0
View
TLS2_k127_1998734_0
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K12256,K15785
-
2.6.1.113,2.6.1.76
9.527e-253
784.0
View
TLS2_k127_1998734_1
Glutamine synthetase, catalytic domain
K01915
GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0034024,GO:0034641,GO:0042402,GO:0044106,GO:0044237,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575
6.3.1.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227
603.0
View
TLS2_k127_1998734_2
Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
K00697
-
2.4.1.15,2.4.1.347
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107
553.0
View
TLS2_k127_1998734_3
-glutamine
K07010
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427
344.0
View
TLS2_k127_1998734_4
Transcriptional regulator
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000428
276.0
View
TLS2_k127_1998734_5
Glycosyl hydrolases family 15
-
-
-
0.00000000000000000000000000000000000000000000000000000000008313
205.0
View
TLS2_k127_1998734_6
Tellurite resistance protein TerB
K05801
-
-
0.000000000000000000000000000000000000000000000000000000001939
212.0
View
TLS2_k127_2002410_0
Dihydrodipicolinate reductase, C-terminus
K00215
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576
1.17.1.8
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892
359.0
View
TLS2_k127_2002410_1
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K10773
-
4.2.99.18
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072
299.0
View
TLS2_k127_2002410_2
Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily
K01834
GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031
5.4.2.11
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002271
282.0
View
TLS2_k127_2002410_3
Etoposide-induced protein 2.4 (EI24)
K06203
-
-
0.0000000000000000000000000000000000000000000000000000006288
198.0
View
TLS2_k127_2002410_4
Diguanylate cyclase
-
-
-
0.00000000000000000000000000000000000000000000000000003518
195.0
View
TLS2_k127_2002410_5
Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)
-
-
-
0.00000000000000000000000000000000000000000000002624
179.0
View
TLS2_k127_2002410_6
Integral membrane protein (DUF2244)
-
-
-
0.0000000000000000000000000000000000000000001726
167.0
View
TLS2_k127_2002410_7
Diguanylate cyclase
-
-
-
0.0000003094
57.0
View
TLS2_k127_2002410_8
PFAM response regulator receiver
-
-
-
0.0000004804
57.0
View
TLS2_k127_2005551_0
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K01918
-
6.3.2.1
0.000000000000000000000000000000000000000000000000000000000000000001043
232.0
View
TLS2_k127_2005551_1
Universal stress protein UspA
-
-
-
0.000000000000000000000000000000000000000009088
165.0
View
TLS2_k127_2005551_2
Protein of unknown function (DUF1489)
-
-
-
0.00000000000000000000000000000000000000007328
158.0
View
TLS2_k127_2014863_0
COG4584 Transposase and inactivated derivatives
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997
608.0
View
TLS2_k127_2020443_0
PFAM AMP-dependent synthetase and ligase
K01897
-
6.2.1.3
1.369e-213
677.0
View
TLS2_k127_2020443_1
Belongs to the thiolase family
K00626,K00632
-
2.3.1.16,2.3.1.9
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496
601.0
View
TLS2_k127_2020443_2
Belongs to the enoyl-CoA hydratase isomerase family
K01782,K01825
-
1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388
518.0
View
TLS2_k127_2020443_3
Uncharacterized protein conserved in bacteria (DUF2147)
-
-
-
0.00000000000000000000001009
114.0
View
TLS2_k127_2038284_0
Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
K02259
-
-
0.00000000000000000000000000000000000000000000000000000000000000001806
235.0
View
TLS2_k127_2038284_1
Polysaccharide deacetylase
-
-
-
0.000000000000000000000000004284
123.0
View
TLS2_k127_2038284_2
Protein of unknown function (DUF2842)
-
-
-
0.0000000000005755
71.0
View
TLS2_k127_2038284_3
Antibiotic biosynthesis monooxygenase
-
-
-
0.000000002443
63.0
View
TLS2_k127_2040834_0
Transposase and inactivated derivatives
-
-
-
5.656e-255
794.0
View
TLS2_k127_2040834_1
insertion sequence ATP-binding protein
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143
377.0
View
TLS2_k127_2040834_2
DDE superfamily endonuclease
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000001421
270.0
View
TLS2_k127_2040834_3
Transposase
-
-
-
0.0000000000000000000000000000000000000000477
163.0
View
TLS2_k127_2040834_4
Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
K07484
-
-
0.0000000000000000000000000000000000005624
140.0
View
TLS2_k127_2048423_0
MotA/TolQ/ExbB proton channel family
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000008768
246.0
View
TLS2_k127_2048423_1
Biopolymer transport protein
K03559,K03560
-
-
0.000000000000000000000000000000000000000000000000000000000001343
212.0
View
TLS2_k127_2048423_2
-
-
-
-
0.000000000000000000000000000000000000000002313
160.0
View
TLS2_k127_2048423_5
Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
K03832
-
-
0.0000001625
62.0
View
TLS2_k127_2064727_0
Protein of unknown function (DUF459)
K09795
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000005715
280.0
View
TLS2_k127_2064727_1
glutamate synthase
K00266
-
1.4.1.13,1.4.1.14
0.000000000000000000000000000000000000000000000000000000000000000000007659
236.0
View
TLS2_k127_2065250_0
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
K02316
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285
522.0
View
TLS2_k127_2087073_0
phenylalanyl-tRNA synthetase, beta subunit
K01890
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494
6.1.1.20
6.713e-237
745.0
View
TLS2_k127_2087073_1
GMC oxidoreductase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963
599.0
View
TLS2_k127_2087073_2
Bacterial capsule synthesis protein PGA_cap
K07282
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000005384
258.0
View
TLS2_k127_2087073_3
Peptide methionine sulfoxide reductase
K07304
-
1.8.4.11
0.00000000000000000000000000000000000000004007
158.0
View
TLS2_k127_2096800_0
Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)
K01770,K12506
-
2.7.7.60,4.6.1.12
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219
381.0
View
TLS2_k127_2096800_1
Competence-damaged protein
K03743
-
3.5.1.42
0.0000000000000000000000000000000000000000000000216
176.0
View
TLS2_k127_2096800_2
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K03644
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576
2.8.1.8
0.000000000000000000000000000000000000000000002425
166.0
View
TLS2_k127_2096800_3
Oligoketide cyclase lipid transport protein
K18588
-
-
0.00000000000000000000000000000000000000000005414
166.0
View
TLS2_k127_2097068_0
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K18979
GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659
1.17.99.6
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677
480.0
View
TLS2_k127_2097068_1
glutathione S-transferase
K00799
-
2.5.1.18
0.000000000000000000000000000000000000000000000000000000000000000000000000000003273
269.0
View
TLS2_k127_2097068_2
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
K06153
GO:0008150,GO:0042221,GO:0046677,GO:0050896
3.6.1.27
0.00000000000000000000000000000000007638
136.0
View
TLS2_k127_2113879_0
Transposase DDE domain group 1
-
-
-
2.987e-259
803.0
View
TLS2_k127_2113879_1
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K01868
-
6.1.1.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009351
497.0
View
TLS2_k127_2113879_2
Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
K01433
-
3.5.1.10
0.0000000000000000000000000000000002115
134.0
View
TLS2_k127_2117713_0
Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
K01586
GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
4.1.1.20
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032
557.0
View
TLS2_k127_2117713_1
Domain of unknown function (DUF4175)
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327
387.0
View
TLS2_k127_2118029_0
Aminotransferase class I and II
K14261,K14267
-
2.6.1.17
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644
418.0
View
TLS2_k127_2118029_1
4TM region of DNA translocase FtsK/SpoIIIE
K03466
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807
323.0
View
TLS2_k127_2118029_2
ammonium transporter
K03320
-
-
0.00000000000000000000000000000000004844
135.0
View
TLS2_k127_2119487_0
Catalyzes the reversible phosphorylation of UMP to UDP
K09903
-
2.7.4.22
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109
310.0
View
TLS2_k127_2119487_1
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K00806
GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617
2.5.1.31
0.00000000000000000000000000000000000000000000000000000000000000000000000000004107
265.0
View
TLS2_k127_2119487_2
Ribosome recycling factor
K02838
GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576
-
0.00000000000000000000000000000000000000000000000000000000000000000000005231
244.0
View
TLS2_k127_2161659_0
inositol mono-phosphatase
K01092,K18649
-
3.1.3.15,3.1.3.25,3.1.3.93
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006798
293.0
View
TLS2_k127_2161659_1
Serine aminopeptidase, S33
K01048
-
3.1.1.5
0.00000000000000000000000000000000000001084
149.0
View
TLS2_k127_2164037_0
Belongs to the CarB family
K01955
-
6.3.5.5
0.0
1524.0
View
TLS2_k127_2164037_1
Belongs to the bacterial glucokinase family
K00845
-
2.7.1.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001289
282.0
View
TLS2_k127_2164037_2
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
K03624
-
-
0.0000000000000000000000000000000000000000000000000000000000000006641
222.0
View
TLS2_k127_21845_0
Sigma-54 interaction domain
K13599
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982
324.0
View
TLS2_k127_21845_1
GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K03665
GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002777
279.0
View
TLS2_k127_21845_2
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
K03666
GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363
-
0.00000000000000000000000000000000000000002596
153.0
View
TLS2_k127_2211240_0
Peptidase M23
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193
512.0
View
TLS2_k127_2211240_1
-
-
-
-
0.000000000000006787
77.0
View
TLS2_k127_2216271_0
phosphatase
K07093
-
-
5.284e-236
752.0
View
TLS2_k127_2216271_1
Redoxin
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995
306.0
View
TLS2_k127_2216271_2
TIGRFAM glutamine synthetase, type I
K01915
-
6.3.1.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193
291.0
View
TLS2_k127_2222719_0
DNA ligase
K01971
-
6.5.1.1
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153
569.0
View
TLS2_k127_2222719_1
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
K10979
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004043
286.0
View
TLS2_k127_2222719_2
DNA ligase D
K01971
-
6.5.1.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000003253
267.0
View
TLS2_k127_2222719_3
Extensin-like protein C-terminus
-
-
-
0.00000000000000000000000000000000000000000000000000000000002799
213.0
View
TLS2_k127_2222719_4
Wd-40 repeat
-
-
-
0.0000000000000000006669
91.0
View
TLS2_k127_2231655_0
Glycosyl transferase 4-like
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208
338.0
View
TLS2_k127_2231655_1
Polysaccharide biosynthesis/export protein
K01991
-
-
0.0000000000000000000000000000000000000000001335
165.0
View
TLS2_k127_2245252_0
Histidine kinase
K07716
-
2.7.13.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709
424.0
View
TLS2_k127_2245252_1
gag-polyprotein putative aspartyl protease
K06985
-
-
0.0000000000000000000000000000000000000000000000000000000002986
214.0
View
TLS2_k127_2245252_2
PFAM ErfK YbiS YcfS YnhG family protein
-
-
-
0.0000000000000000000000000000000000000000001934
167.0
View
TLS2_k127_2245252_3
Protein of unknown function (DUF1289)
K06938
-
-
0.0000000000006248
72.0
View
TLS2_k127_2250362_0
Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
K02275
-
1.9.3.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531
331.0
View
TLS2_k127_2250362_1
Invasion associated locus B
-
-
-
0.000000000000000000000000000000000000000000000000007435
186.0
View
TLS2_k127_2250362_2
glutamate--cysteine ligase
K01919
-
6.3.2.2
0.00000000000003877
74.0
View
TLS2_k127_2250362_3
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K02274
-
1.9.3.1
0.00000000002023
65.0
View
TLS2_k127_2280646_0
Phosphoribosyl transferase domain
K00760
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
2.4.2.8
0.0000000000000000000000000000000000000000000000000000001243
202.0
View
TLS2_k127_2280646_1
protein conserved in bacteria
-
-
-
0.0000000000000000000000001181
107.0
View
TLS2_k127_2280646_2
TIGRFAM MJ0042 family finger-like protein
-
-
-
0.000000000002222
78.0
View
TLS2_k127_2323768_0
Protein of unknown function (DUF1214)
-
-
-
0.00000000000000000000000000000000000000000001244
170.0
View
TLS2_k127_2323768_1
Protein of unknown function (DUF1491)
-
-
-
0.0000000000000000000000000000004446
125.0
View
TLS2_k127_2323768_2
integral membrane protein
-
-
-
0.00000000000000000000000000000716
126.0
View
TLS2_k127_2323768_3
Putative peptidoglycan binding domain
-
-
-
0.0000000000000000000007207
102.0
View
TLS2_k127_2368942_0
copper-translocating P-type ATPase
K01533
-
3.6.3.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559
524.0
View
TLS2_k127_2368942_1
Probable molybdopterin binding domain
K07141
-
2.7.7.76
0.000000000000000000000000000000000000000000000000001128
193.0
View
TLS2_k127_2368942_2
helix_turn_helix ASNC type
K03719
-
-
0.0000000000000000000000000001252
116.0
View
TLS2_k127_2368942_3
Cytochrome oxidase maturation protein cbb3-type
-
-
-
0.000000000002391
71.0
View
TLS2_k127_2381813_0
Flavodoxin-like fold
K03809
-
1.6.5.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394
297.0
View
TLS2_k127_2381813_1
Belongs to the Nudix hydrolase family
-
-
-
0.00000000000000000000000000000000000000000000436
171.0
View
TLS2_k127_2381813_2
Calcineurin-like phosphoesterase superfamily domain
-
-
-
0.000000000000000000000000000000000000002971
149.0
View
TLS2_k127_2396757_0
poly(R)-hydroxyalkanoic acid synthase
K03821
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
-
1.938e-264
825.0
View
TLS2_k127_2396757_1
Putative zinc-binding metallo-peptidase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931
431.0
View
TLS2_k127_2396757_2
ATP-grasp domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321
326.0
View
TLS2_k127_2403668_0
Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
K00560
-
2.1.1.45
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239
443.0
View
TLS2_k127_2403668_1
HflC and HflK could encode or regulate a protease
K04088
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615
437.0
View
TLS2_k127_2403668_2
HflC and HflK could regulate a protease
K04087
-
-
0.000000000000000000000000000000000000000000000003189
178.0
View
TLS2_k127_2403668_3
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K00287
-
1.5.1.3
0.000000000000000000000000000000000000000000000008927
177.0
View
TLS2_k127_2403668_4
Stringent starvation protein B
K09985
-
-
0.00000000000000000000000000008768
118.0
View
TLS2_k127_2403668_5
TIGRFAM addiction module antidote protein, HigA family
K21498
-
-
0.0000000000000000000000000007661
115.0
View
TLS2_k127_2403668_6
RelE-like toxin of type II toxin-antitoxin system HigB
-
-
-
0.0000000000000000007523
87.0
View
TLS2_k127_2403668_7
-
-
-
-
0.00000000008397
64.0
View
TLS2_k127_2417373_0
ATPase involved in DNA repair
K03546
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877
521.0
View
TLS2_k127_2417373_1
Mur ligase middle domain
K01929
-
6.3.2.10
0.00000000000000000000000000000000000000000000001964
180.0
View
TLS2_k127_2417373_2
ABC-type transport auxiliary lipoprotein component
K18480
-
-
0.00000000000000000000004374
102.0
View
TLS2_k127_2417373_3
Histidine Phosphotransfer domain
-
-
-
0.00000000000000000006149
97.0
View
TLS2_k127_2417373_4
ferredoxin
K04755
-
-
0.0006648
44.0
View
TLS2_k127_2427418_0
heme copper-type cytochrome quinol oxidase, subunit 3
K02276
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
1.9.3.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154
418.0
View
TLS2_k127_2427418_1
Threonine synthase
K01733
GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
4.2.3.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808
399.0
View
TLS2_k127_2427418_2
SURF1 family
K14998
GO:0006996,GO:0007005,GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0033108,GO:0033617,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840
-
0.000000000000000000000000000000000000000000000000000000000666
214.0
View
TLS2_k127_2427418_3
Protein of unknown function (DUF983)
-
-
-
0.000000000000000000000000000000000000000002729
158.0
View
TLS2_k127_2439798_0
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K01662
-
2.2.1.7
3.973e-249
779.0
View
TLS2_k127_2439798_1
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
-
-
-
0.00000000000000000000000000000000000000000000811
166.0
View
TLS2_k127_2439798_2
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
K07117
-
-
0.00000000000000000000000000000000000000000004913
164.0
View
TLS2_k127_24424_0
B3/4 domain
K01890
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494
6.1.1.20
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184
587.0
View
TLS2_k127_24424_1
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K01889
GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576
6.1.1.20
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744
556.0
View
TLS2_k127_24424_2
PFAM GGDEF domain containing protein
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897
407.0
View
TLS2_k127_24424_3
Glycosyl transferase 4-like
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004
374.0
View
TLS2_k127_24424_4
Translation initiation factor IF-3, N-terminal domain
K02520
GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000008136
261.0
View
TLS2_k127_24424_5
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K02887
GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840
-
0.0000000000000000000000000000000000000000000000000022
184.0
View
TLS2_k127_24424_6
GrpB protein
-
-
-
0.00000000000000000000000001091
126.0
View
TLS2_k127_24424_7
Ribosomal protein L35
K02916
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904
-
0.0000000000000000000002996
99.0
View
TLS2_k127_2470694_0
Bacterial transglutaminase-like cysteine proteinase BTLCP
-
-
-
0.0000000000000000000000000000000000000000000000005045
181.0
View
TLS2_k127_2470694_1
PFAM type IV pilus assembly PilZ
-
-
-
0.000000000000000000000000000000004873
132.0
View
TLS2_k127_2470694_2
PAS domain
-
-
-
0.00000000000000000000000000168
118.0
View
TLS2_k127_2470694_3
PilZ domain
-
-
-
0.00000000000000000000002009
104.0
View
TLS2_k127_24719_0
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K00648
-
2.3.1.180
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192
466.0
View
TLS2_k127_24719_1
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
K03621
-
2.3.1.15
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198
457.0
View
TLS2_k127_24719_2
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
K04764
-
-
0.00000000000000000000000000000000000000000003675
162.0
View
TLS2_k127_24719_3
PFAM regulatory protein MerR
-
-
-
0.000000000000000000000000000000000000003922
151.0
View
TLS2_k127_24719_4
Uncharacterized ACR, COG1399
-
-
-
0.00000000000000000000000001421
116.0
View
TLS2_k127_2485178_0
Extracellular solute-binding protein
K02035,K13893
-
-
4.869e-239
764.0
View
TLS2_k127_2485178_1
PFAM binding-protein-dependent transport systems inner membrane component
K13894
GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362
557.0
View
TLS2_k127_2485178_2
Bacterial extracellular solute-binding proteins, family 5 Middle
K02035,K13893
-
-
0.000000000000000000000000000000000000000000000000000000000000203
215.0
View
TLS2_k127_2485178_3
N-terminal TM domain of oligopeptide transport permease C
K13895
GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944
-
0.000000000000000000000000000000000000000000000000000000000001229
213.0
View
TLS2_k127_249773_0
UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K13308,K20429
GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771
2.6.1.33
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115
318.0
View
TLS2_k127_2503127_0
-
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487
507.0
View
TLS2_k127_2503127_1
Belongs to the sigma-70 factor family. ECF subfamily
K03088
-
-
0.00000000000000000000000000000000000000000000000000000001143
203.0
View
TLS2_k127_2503127_2
AntiSigma factor
-
-
-
0.000000000000001686
85.0
View
TLS2_k127_2592109_0
Belongs to the CarB family
K01955
-
6.3.5.5
4.607e-271
851.0
View
TLS2_k127_2592109_1
Carbamoyl-phosphate synthase small chain, CPSase domain
K01956
GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494
6.3.5.5
0.000000000000000000000000000000000000000000000000000000000000000000000001603
245.0
View
TLS2_k127_2592109_2
Belongs to the peptidase S11 family
K07258
-
3.4.16.4
0.00000000000007435
82.0
View
TLS2_k127_2625249_0
L-asparaginase II
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001
335.0
View
TLS2_k127_2625249_1
helix_turn_helix ASNC type
-
GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141
-
0.0000000000000000000000000000000000000000000000000000000121
201.0
View
TLS2_k127_2625249_2
Periplasmic copper-binding protein (NosD)
-
-
-
0.000000000000000000000000000000000003709
140.0
View
TLS2_k127_2625249_3
Protein of unknown function (DUF992)
-
-
-
0.000000000000000000000000000009988
124.0
View
TLS2_k127_263010_0
Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
K01499
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
3.5.4.27
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375
380.0
View
TLS2_k127_263010_1
Methylene-tetrahydromethanopterin dehydrogenase, N-terminal
K10714
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946
355.0
View
TLS2_k127_263010_2
ATP-grasp domain
K06913
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008542
290.0
View
TLS2_k127_263010_3
transferase activity, transferring glycosyl groups
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000004723
276.0
View
TLS2_k127_263010_4
Belongs to the RimK family
K05844
-
-
0.000000000000000000000000000000000000000000000000000002788
196.0
View
TLS2_k127_263010_5
PFAM Pterin 4 alpha carbinolamine dehydratase
K01724
-
4.2.1.96
0.00000000001744
64.0
View
TLS2_k127_2670437_0
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
K01595
-
4.1.1.31
4.206e-223
709.0
View
TLS2_k127_2670437_1
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
K01903,K14067
-
6.2.1.5,6.2.1.9
1.074e-212
665.0
View
TLS2_k127_2670437_2
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K01902,K08692
-
6.2.1.5,6.2.1.9
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752
513.0
View
TLS2_k127_2670437_3
PFAM Formiminotransferase-cyclodeaminase
-
-
-
0.0000000000009271
69.0
View
TLS2_k127_268183_0
RimK-like ATP-grasp domain
K05844
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657
297.0
View
TLS2_k127_268183_1
Putative ATP-dependant zinc protease
-
-
-
0.0000000000000000000000000000000000000000000002622
172.0
View
TLS2_k127_268183_2
MTH538 TIR-like domain (DUF1863)
-
-
-
0.00000000000000000000000000000000229
140.0
View
TLS2_k127_268183_3
Uncharacterized protein conserved in bacteria (DUF2188)
-
-
-
0.0000000000000859
74.0
View
TLS2_k127_268183_4
Sulfatase-modifying factor enzyme 1
-
-
-
0.0000000001985
68.0
View
TLS2_k127_268483_0
Class II Aldolase and Adducin N-terminal domain
-
-
-
2.476e-225
713.0
View
TLS2_k127_268483_1
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K02986
GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623
348.0
View
TLS2_k127_268483_2
alpha/beta hydrolase fold
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000001016
243.0
View
TLS2_k127_268483_3
-
-
-
-
0.0000000000000000004482
98.0
View
TLS2_k127_268483_4
Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
K02533
-
-
0.0000000003071
61.0
View
TLS2_k127_2713925_0
Histidine kinase
K15011
-
2.7.13.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965
385.0
View
TLS2_k127_2713925_1
response regulator
K15012
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000003073
275.0
View
TLS2_k127_2713925_2
DNA repair protein MmcB-like
-
-
-
0.0000000000000000000000000000000000000000000000008785
179.0
View
TLS2_k127_2713925_3
DinB superfamily
-
-
-
0.00000000000000000004086
93.0
View
TLS2_k127_273668_0
COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
K01999
-
-
5.83e-205
647.0
View
TLS2_k127_273668_1
L-lysine 6-monooxygenase (NADPH-requiring)
K18277
-
1.14.13.148
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281
405.0
View
TLS2_k127_273668_2
Belongs to the binding-protein-dependent transport system permease family
K01997
-
-
0.000000000002665
68.0
View
TLS2_k127_2826947_0
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K03723
-
-
0.0
1507.0
View
TLS2_k127_2826947_1
Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K03655
-
3.6.4.12
6.544e-254
802.0
View
TLS2_k127_2826947_2
Flavinator of succinate dehydrogenase
K09159
-
-
0.00000000000001263
77.0
View
TLS2_k127_2826947_3
AMP-binding enzyme C-terminal domain
-
-
-
0.00000000003407
70.0
View
TLS2_k127_2826947_4
AMP-binding enzyme C-terminal domain
-
-
-
0.00001359
48.0
View
TLS2_k127_2831699_0
Domain of unknown function (DUF3390)
K18929
-
-
1.197e-197
626.0
View
TLS2_k127_2831699_1
glycolate oxidase iron-sulfur subunit
K18928
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352
336.0
View
TLS2_k127_2831699_2
Part of the tripartite ATP-independent periplasmic (TRAP) transport system
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006516
301.0
View
TLS2_k127_2831699_3
LUD domain
K00782
-
-
0.0000000000000000000000000000000000000000000000000000006092
210.0
View
TLS2_k127_2831699_4
Cytochrome c
K08738
GO:0005575,GO:0005623,GO:0042597,GO:0044464
-
0.0000000000000000000002178
105.0
View
TLS2_k127_2835852_0
Belongs to the glutaminase family
K01425
-
3.5.1.2
0.000000000000000000000000000000000000000000000000000000000000001089
230.0
View
TLS2_k127_2835852_1
HWE histidine kinase
-
-
-
0.000000000000000000000000000000000000000000000002031
184.0
View
TLS2_k127_2838374_0
Transposase and inactivated derivatives
-
-
-
2.16e-224
701.0
View
TLS2_k127_2838374_1
insertion sequence ATP-binding protein
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363
334.0
View
TLS2_k127_2838374_2
DNA methylase N-4 N-6
K07316
-
2.1.1.72
0.000000000000000000003681
98.0
View
TLS2_k127_2838374_3
IstB-like ATP binding N-terminal
-
-
-
0.0002964
44.0
View
TLS2_k127_2843492_0
Penicillin-binding protein OB-like domain
K05366
-
2.4.1.129,3.4.16.4
2.447e-198
632.0
View
TLS2_k127_2843492_1
Ami_3
K01448
-
3.5.1.28
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564
380.0
View
TLS2_k127_2843492_2
Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs
K08300
-
3.1.26.12
0.0000000009256
63.0
View
TLS2_k127_2844204_0
Fumarylacetoacetate (FAA) hydrolase family
K01826
-
5.3.3.10
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394
355.0
View
TLS2_k127_2844204_1
Phosphomethylpyrimidine kinase
K00941
-
2.7.1.49,2.7.4.7
0.000000000000000000000000000000000000000000000001347
177.0
View
TLS2_k127_2847143_0
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K01338
-
3.4.21.53
0.000000000000000000000000000000000000000000000000000000000000000000000000001265
257.0
View
TLS2_k127_2847143_1
Aminoglycoside 3-N-acetyltransferase
K00662
-
2.3.1.81
0.0000000000000000000000000002917
119.0
View
TLS2_k127_2847143_2
aminoglycoside 3-N-acetyltransferase activity
K00662
-
2.3.1.81
0.00000000004401
71.0
View
TLS2_k127_2847143_3
Cyclic nucleotide-monophosphate binding domain
-
-
-
0.0000001158
55.0
View
TLS2_k127_2847143_4
-
-
-
-
0.000002697
53.0
View
TLS2_k127_2848592_0
alcohol dehydrogenase
K13979
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107
541.0
View
TLS2_k127_2848592_1
-
-
-
-
0.00000000000000000000000000000000001689
145.0
View
TLS2_k127_2855764_0
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K00014
-
1.1.1.25
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189
323.0
View
TLS2_k127_2855764_1
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K02342
-
2.7.7.7
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000102
274.0
View
TLS2_k127_2855764_2
import inner membrane translocase, subunit Tim44
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000002191
252.0
View
TLS2_k127_2855764_3
Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
K09773
-
2.7.11.33,2.7.4.28
0.000000000000000000000000000000000000000000000000000000000000000002829
229.0
View
TLS2_k127_2855764_4
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K00859
GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
2.7.1.24
0.000000000000000000000000000000000000000000000000000000000001097
218.0
View
TLS2_k127_2855764_5
Maf-like protein
K06287
-
-
0.000000000000000000000000000000000000000000000000000001047
205.0
View
TLS2_k127_2855764_6
One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
K03071
GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705
-
0.0000000000000000000000000000000000000000000000007467
182.0
View
TLS2_k127_2858352_0
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
K03703
GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391
-
3.684e-272
850.0
View
TLS2_k127_2858352_1
Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K00995,K08744
-
2.7.8.41,2.7.8.5
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001908
281.0
View
TLS2_k127_2858352_2
Enoyl-(Acyl carrier protein) reductase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005233
284.0
View
TLS2_k127_2858352_3
Linear amide C-N hydrolases, choloylglycine hydrolase family
K01442
-
3.5.1.24
0.000000000000000000000000000000000000000000000000000000000000000000003464
239.0
View
TLS2_k127_2858352_4
MoaE protein
K03635
-
2.8.1.12
0.00000000000000000000000000000000000000000000000000000003205
201.0
View
TLS2_k127_2858352_5
ThiS family
K03636
-
-
0.0000000000000000000000000000283
118.0
View
TLS2_k127_28592_0
Domain of unknown function (DUF1974)
K06445
-
-
0.0
1063.0
View
TLS2_k127_28592_1
CDGSH-type zinc finger. Function unknown.
-
-
-
0.00000000000000000000000000001415
119.0
View
TLS2_k127_28592_2
Belongs to the binding-protein-dependent transport system permease family
K01997
-
-
0.000000001611
63.0
View
TLS2_k127_2861142_0
Orn DAP Arg decarboxylase 2
K01581
-
4.1.1.17
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153
389.0
View
TLS2_k127_2861142_1
Cytochrome c, mono- and diheme variants
-
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322
364.0
View
TLS2_k127_2861142_2
PFAM Sel1 domain protein repeat-containing protein
K07126
-
-
0.0000000000000000000000000000000004678
149.0
View
TLS2_k127_2861142_3
Belongs to the GST superfamily
K11209
-
-
0.000000000000000001069
86.0
View
TLS2_k127_287392_0
Glutamate synthase central domain
K00265
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
1.4.1.13,1.4.1.14
0.0
1596.0
View
TLS2_k127_287392_1
Glutamate synthase
K00266
-
1.4.1.13,1.4.1.14
9.034e-247
768.0
View
TLS2_k127_287392_2
Protein of unknown function (DUF459)
K09795
-
-
0.000003172
49.0
View
TLS2_k127_2874908_0
Phosphoribosylformylglycinamidine cyclo-ligase
K01933
-
6.3.3.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889
454.0
View
TLS2_k127_2874908_1
cytochrome P450
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004695
282.0
View
TLS2_k127_2874908_2
Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K11175
GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716
2.1.2.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000007249
267.0
View
TLS2_k127_2874908_3
Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K00995,K08744
-
2.7.8.41,2.7.8.5
0.0000000000000000000000000000000000000000000000000000000006404
209.0
View
TLS2_k127_2874908_4
Belongs to the DnaA family
-
-
-
0.00000000000000000000000000000000000000000000000000000007808
205.0
View
TLS2_k127_2874908_5
Uncharacterized protein conserved in bacteria (DUF2066)
-
-
-
0.0000000000000000000000000000000000005491
154.0
View
TLS2_k127_2879575_0
Involved in initiation control of chromosome replication
K07484
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936
616.0
View
TLS2_k127_2897340_0
Diguanylate cyclase phosphodiesterase with PAS PAC
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612
413.0
View
TLS2_k127_2897340_1
Enoyl- acyl-carrier-protein reductase NADH
K00208
-
1.3.1.10,1.3.1.9
0.0000000000000000000000000000000000000000000000000000000000001503
214.0
View
TLS2_k127_2897340_2
Belongs to the SOS response-associated peptidase family
-
-
-
0.0000000000000000000000000000000000000000000000000000113
196.0
View
TLS2_k127_2897340_3
Diguanylate cyclase
-
GO:0000302,GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008081,GO:0008150,GO:0009987,GO:0010035,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042578,GO:0050896,GO:0051716,GO:0052621,GO:0070887,GO:0071111,GO:0071241,GO:0071731,GO:0071732,GO:0097366,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170
-
0.0000000000000000000000000000000000000002484
163.0
View
TLS2_k127_2897340_4
C-terminal region of aryl-sulfatase
K01130
-
3.1.6.1
0.0000000000000000577
82.0
View
TLS2_k127_2897340_5
Diguanylate cyclase phosphodiesterase with PAS PAC
-
-
-
0.00000000000001423
81.0
View
TLS2_k127_2897340_6
17 kDa outer membrane surface antigen
-
-
-
0.0006611
48.0
View
TLS2_k127_290991_0
Signal transduction histidine kinase
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986
469.0
View
TLS2_k127_290991_1
Transcriptional regulatory protein, C terminal
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293
348.0
View
TLS2_k127_290991_2
cytochrome P450
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000576
219.0
View
TLS2_k127_290991_3
peptidase
-
-
-
0.0000000000000000000445
93.0
View
TLS2_k127_290991_4
Peptidase propeptide and YPEB domain
-
-
-
0.0000000000000000003123
94.0
View
TLS2_k127_290991_5
PFAM Adenosine AMP deaminase
K01488
-
3.5.4.4
0.0000000342
56.0
View
TLS2_k127_290991_6
-
-
-
-
0.0003927
49.0
View
TLS2_k127_2910139_0
PFAM Alcohol dehydrogenase GroES-like domain
K00344
GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003960,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016651,GO:0016655,GO:0017091,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:1901363
1.6.5.5
0.000000000000000000000000000000000000008327
146.0
View
TLS2_k127_2910139_1
COG0790 FOG TPR repeat, SEL1 subfamily
K07126
-
-
0.00000000000000000000001217
103.0
View
TLS2_k127_2910139_2
Cyclic nucleotide-monophosphate binding domain
-
-
-
0.0000000000002413
72.0
View
TLS2_k127_291048_0
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
K00820
GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576
2.6.1.16
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876
368.0
View
TLS2_k127_291048_1
Protein of unknown function (DUF502)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000001469
265.0
View
TLS2_k127_2914136_0
Polyphosphate kinase 2 (PPK2)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824
379.0
View
TLS2_k127_2914136_1
O-methyltransferase
K00588
-
2.1.1.104
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006837
286.0
View
TLS2_k127_2914136_2
SOS response associated peptidase (SRAP)
-
-
-
0.000000000000000000278
89.0
View
TLS2_k127_2914136_3
Fad linked oxidase
K00104
-
1.1.3.15
0.0000000000002497
70.0
View
TLS2_k127_2926175_0
Transglycosylase SLT domain
K08305
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048
478.0
View
TLS2_k127_2926175_1
ATP dependent DNA ligase domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922
364.0
View
TLS2_k127_2926175_2
Protein of unknown function (DUF3072)
-
-
-
0.0000000006496
64.0
View
TLS2_k127_2926175_3
damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
K03702
-
-
0.00002997
47.0
View
TLS2_k127_2926175_4
SnoaL-like domain
-
-
-
0.0006633
48.0
View
TLS2_k127_2933628_0
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
K07638
-
2.7.13.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284
518.0
View
TLS2_k127_2933628_1
Two component transcriptional regulator
K07659
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226
316.0
View
TLS2_k127_294363_0
C-terminal domain of 1-Cys peroxiredoxin
K03386
-
1.11.1.15
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124
420.0
View
TLS2_k127_294363_1
DJ-1/PfpI family
K05520
-
3.5.1.124
0.00000000000000000000000000000000000000000000000000000000000000000000000000000004972
272.0
View
TLS2_k127_294363_2
NUDIX domain
K03574
-
3.6.1.55
0.00000000000000000000000000000000001198
140.0
View
TLS2_k127_294363_3
High-affinity nickel-transport protein
K08970
-
-
0.000000000000000000000000000000001949
133.0
View
TLS2_k127_294363_4
Catalyzes the ferrous insertion into protoporphyrin IX
K01772
GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
4.99.1.1,4.99.1.9
0.0000000000000000000000000004292
118.0
View
TLS2_k127_2953395_0
Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
K02621
-
-
1.666e-254
792.0
View
TLS2_k127_2955347_0
FMN-dependent dehydrogenase
K00467
-
1.13.12.4
3.84e-200
631.0
View
TLS2_k127_2955347_1
Protein of unknown function (DUF2852)
-
-
-
0.00000000000000000000000000000000000000003707
156.0
View
TLS2_k127_2955987_0
Belongs to the heme-copper respiratory oxidase family
K00404
GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600
1.9.3.1
8.218e-293
906.0
View
TLS2_k127_2955987_1
TIGRFAM cytochrome c oxidase, cbb3-type, subunit II
K00405
-
-
0.00000000000000000000000000000000000000000000000000000000001134
207.0
View
TLS2_k127_2955987_2
Belongs to the 'phage' integrase family
-
-
-
0.000000000000000000000000000000000000000003537
160.0
View
TLS2_k127_2955987_3
Belongs to the 'phage' integrase family
-
-
-
0.000000000000000000000000001744
118.0
View
TLS2_k127_2967990_0
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K02886
GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452
464.0
View
TLS2_k127_2967990_1
Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K02982
GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045
380.0
View
TLS2_k127_2967990_10
Involved in the binding of tRNA to the ribosomes
K02946
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000003575
110.0
View
TLS2_k127_2967990_11
Belongs to the universal ribosomal protein uL29 family
K02904
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904
-
0.0000000000000000005499
91.0
View
TLS2_k127_2967990_2
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K02906
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477
369.0
View
TLS2_k127_2967990_3
Ribosomal protein L4/L1 family
K02926
GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006442
283.0
View
TLS2_k127_2967990_4
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
K02878
GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904
-
0.000000000000000000000000000000000000000000000000000000000000001517
220.0
View
TLS2_k127_2967990_5
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K02890
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904
-
0.000000000000000000000000000000000000000000000000000001503
194.0
View
TLS2_k127_2967990_6
Ribosomal protein S19
K02965
GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904
-
0.0000000000000000000000000000000000000000000000006896
175.0
View
TLS2_k127_2967990_7
Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K02874
GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904
-
0.000000000000000000000000000000000000008317
145.0
View
TLS2_k127_2967990_8
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K02961
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000000000003984
129.0
View
TLS2_k127_2967990_9
One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
K02892
GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.00000000000000000000000000000000799
130.0
View
TLS2_k127_2974381_0
Cytochrome P450
K15629
-
1.11.2.4
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979
434.0
View
TLS2_k127_2974381_1
Cytochrome C and Quinol oxidase polypeptide I
K15408
-
1.9.3.1
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006117
288.0
View
TLS2_k127_2974381_2
cytochrome C oxidase
K02351
-
-
0.0000000000000000000000000000000000000000000000002424
189.0
View
TLS2_k127_2974381_3
-
-
-
-
0.000000000000000000003841
97.0
View
TLS2_k127_2992962_0
PFAM Peptidase M1 membrane alanine aminopeptidase
K01256
GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564
3.4.11.2
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222
527.0
View
TLS2_k127_2992962_1
-
-
-
-
0.00000000000000000000000000000000000000000000000000001785
195.0
View
TLS2_k127_2992962_3
-
-
-
-
0.0000000004215
68.0
View
TLS2_k127_2993052_0
Polysaccharide deacetylase
-
-
-
0.0000000000000000000000000000000000000000000006338
173.0
View
TLS2_k127_2993052_1
Chain length determinant protein
-
-
-
0.00000000000000000000000000000008744
140.0
View
TLS2_k127_2993052_2
Chain length determinant protein
-
-
-
0.000000000000000000000000000002049
127.0
View
TLS2_k127_2993052_3
Acetyltransferase (GNAT) domain
-
-
-
0.0000000000000001448
91.0
View
TLS2_k127_2993052_4
Acetyltransferase (GNAT) domain
-
-
-
0.0000000003602
70.0
View
TLS2_k127_2993052_5
protein involved in
-
-
-
0.000000005486
64.0
View
TLS2_k127_3000443_0
NmrA-like family
K00329,K00356
-
1.6.5.3,1.6.99.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405
396.0
View
TLS2_k127_3000443_1
3'-5' exonuclease
K03684
-
3.1.13.5
0.0000000000000000000000000000000000000000000000000000000000000004424
223.0
View
TLS2_k127_3000443_2
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
K06153
GO:0008150,GO:0042221,GO:0046677,GO:0050896
3.6.1.27
0.000000000000000000000000000000000000000000000000000000000005261
213.0
View
TLS2_k127_3045339_0
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
K00164
-
1.2.4.2
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833
505.0
View
TLS2_k127_3045339_1
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K01902
-
6.2.1.5
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553
471.0
View
TLS2_k127_3045339_2
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
K01903
GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350
6.2.1.5
0.0000000000000000000000000000000000000000000000000000000000000000000000000009002
256.0
View
TLS2_k127_3071034_0
Phosphate acyltransferases
K00655
-
2.3.1.51
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647
319.0
View
TLS2_k127_3071034_1
Scaffold protein Nfu NifU
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008861
281.0
View
TLS2_k127_3071034_2
Belongs to the Fur family
K03711
-
-
0.000000000000000000000000000000000000000000000000000000002615
203.0
View
TLS2_k127_3071034_3
Glycoprotease family
K01409,K14742
-
2.3.1.234
0.00000000000000000000000000000000000002232
156.0
View
TLS2_k127_3071034_4
Acetyltransferase (GNAT) domain
K03789
-
2.3.1.128
0.0000000000000001327
89.0
View
TLS2_k127_3082510_0
helicase superfamily c-terminal domain
K17675
-
3.6.4.13
1.152e-286
900.0
View
TLS2_k127_3082510_1
CHASE
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786
478.0
View
TLS2_k127_3082510_2
Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit
K04762
-
-
0.0000000000000000000000001198
109.0
View
TLS2_k127_3104760_0
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K01681
GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363
4.2.1.3
9.71e-231
721.0
View
TLS2_k127_3104760_1
Protein of unknown function (DUF1223)
-
-
-
0.000000000000000000000000000000000000000000003611
169.0
View
TLS2_k127_3104760_2
acetyltransferase
-
-
-
0.00000000000000000000000000000000000000001916
160.0
View
TLS2_k127_3107735_0
Sugar transferase
K03606,K20997
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000002305
261.0
View
TLS2_k127_3107735_1
polysaccharide biosynthetic process
-
-
-
0.000000000000000000000000000000000000000000000000001211
188.0
View
TLS2_k127_3107735_2
Methyltransferase domain
K00568
-
2.1.1.222,2.1.1.64
0.000000007473
65.0
View
TLS2_k127_312299_0
Proton-conducting membrane transporter
K05568
-
-
3.298e-196
622.0
View
TLS2_k127_312299_1
Proton-conducting membrane transporter
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364
557.0
View
TLS2_k127_312299_2
PFAM NADH Ubiquinone plastoquinone (complex I)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977
436.0
View
TLS2_k127_312299_3
PFAM NADH-ubiquinone oxidoreductase chain 4L
K05567
-
-
0.00000000000000000001152
93.0
View
TLS2_k127_312299_4
-
-
-
-
0.000000000000000001326
85.0
View
TLS2_k127_312299_5
Phage integrase family
-
-
-
0.000000000000000001707
87.0
View
TLS2_k127_314335_0
YmdB-like protein
K09769
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276
416.0
View
TLS2_k127_314335_1
Glycosyl transferase family 2
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221
389.0
View
TLS2_k127_314335_2
TIGRFAM DNA-binding regulatory protein, YebC PmpR family
-
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416
336.0
View
TLS2_k127_314335_3
Sel1-like repeats.
K07126
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000001407
250.0
View
TLS2_k127_314335_4
Catabolite gene activator and regulatory subunit of cAMP-dependent protein
-
-
-
0.00000000000000000000000000000000000000000000000000000004178
206.0
View
TLS2_k127_314335_5
Thiamine monophosphate synthase
K00788
-
2.5.1.3
0.00000000000000000000000000000004976
132.0
View
TLS2_k127_314335_6
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
K09888
-
-
0.0000000000000000000265
95.0
View
TLS2_k127_314335_7
Domain of unknown function (DUF4164)
-
-
-
0.00005458
49.0
View
TLS2_k127_3182868_0
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX
K00228
GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983
1.3.3.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507
379.0
View
TLS2_k127_3182868_1
Domain of unknown function (DUF3597)
-
-
-
0.000000000000000000000001183
111.0
View
TLS2_k127_3182868_2
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX
K00228
GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983
1.3.3.3
0.000000000000001103
79.0
View
TLS2_k127_3211074_0
Oligopeptide/dipeptide transporter, C-terminal region
K02031,K02032,K13896
GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363
-
5.344e-251
784.0
View
TLS2_k127_3211074_1
PFAM NLP P60 protein
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423
302.0
View
TLS2_k127_3211074_2
Belongs to the peptidase M17 family
K01255
-
3.4.11.1
0.000000000000000000000000000000000000002548
148.0
View
TLS2_k127_3220823_0
amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K01870
-
6.1.1.5
0.0
1359.0
View
TLS2_k127_3220823_1
This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K03101
-
3.4.23.36
0.00000000000000000000000000000000000000000000000000000005147
203.0
View
TLS2_k127_3224191_0
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
K00773
-
2.4.2.29
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225
353.0
View
TLS2_k127_3224191_1
EamA-like transporter family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357
299.0
View
TLS2_k127_3224191_2
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K17364
-
1.5.1.47
0.0000000000000000000000000000000000000000000000000000000000003927
216.0
View
TLS2_k127_3224191_4
Domain of unknown function (DUF4864)
-
-
-
0.00004708
53.0
View
TLS2_k127_3245774_0
Zinc-binding dehydrogenase
K00344
-
1.6.5.5
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947
424.0
View
TLS2_k127_3245774_1
Protein of unknown function (DUF1465)
K13592
-
-
0.000000000000000000000000000000000000000000001026
171.0
View
TLS2_k127_3245774_2
Ribosomal protein L31
K02909
-
-
0.000000000000000000000000000000004058
131.0
View
TLS2_k127_3245774_3
Protein of unknown function (DUF1013)
K09987
-
-
0.000000000002485
68.0
View
TLS2_k127_3245774_4
Protein of unknown function (DUF1192)
-
-
-
0.00002397
49.0
View
TLS2_k127_3259320_0
ABC transporter
K15738
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788
335.0
View
TLS2_k127_3259320_1
peptidyl-tyrosine sulfation
-
-
-
0.0000000000000000000000000000000000000000000000007495
182.0
View
TLS2_k127_3259320_2
O-Antigen Polymerase
K02847
-
-
0.00000000000000000000000000002876
132.0
View
TLS2_k127_3259320_3
Sulfotransferase family
-
-
-
0.000000000000002797
85.0
View
TLS2_k127_3320106_0
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
K00820
GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576
2.6.1.16
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709
579.0
View
TLS2_k127_3320106_1
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K04042
-
2.3.1.157,2.7.7.23
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902
497.0
View
TLS2_k127_3349125_0
helicase superfamily c-terminal domain
K17675
-
3.6.4.13
0.00000000000000000000000000000000000000000000000000000000000000000000000000001808
265.0
View
TLS2_k127_3349125_1
Esterase-like activity of phytase
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000008529
271.0
View
TLS2_k127_3349125_2
Protein of unknown function (DUF3108)
-
-
-
0.00000000000000000000000000000000000000002204
164.0
View
TLS2_k127_3349125_3
Belongs to the bacterial ribosomal protein bL28 family
K02902
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904
-
0.00000000000000000000000000000000005692
135.0
View
TLS2_k127_3349125_4
SMART von Willebrand factor type A
K09883
-
6.6.1.2
0.00000000000000000000001797
100.0
View
TLS2_k127_3361437_0
Belongs to the GcvT family
K00605
-
2.1.2.10
0.0
1177.0
View
TLS2_k127_3361437_1
Linear amide C-N hydrolases, choloylglycine hydrolase family
K01442
-
3.5.1.24
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349
351.0
View
TLS2_k127_3361437_2
Haloacid dehalogenase-like hydrolase
K01101,K02566
-
3.1.3.41
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097
310.0
View
TLS2_k127_3361437_3
flavoprotein involved in K transport
K18277
-
1.14.13.148
0.0000000000000000000000000000009564
122.0
View
TLS2_k127_3374207_0
Glucose sorbosone
K00117,K21430
-
1.1.5.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305
410.0
View
TLS2_k127_3374207_1
AAA domain, putative AbiEii toxin, Type IV TA system
K01990
GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844
331.0
View
TLS2_k127_3374207_2
-
-
-
-
0.0000000000000000000000000000000000605
137.0
View
TLS2_k127_3427721_0
Belongs to the class-I aminoacyl-tRNA synthetase family
K04566
-
6.1.1.6
1.173e-243
767.0
View
TLS2_k127_3427721_1
Protein of unknown function, DUF488
-
-
-
0.00000000000000000000000000000000000000000004115
164.0
View
TLS2_k127_3427721_2
PFAM Mo-dependent nitrogenase
-
-
-
0.0000000000000002114
79.0
View
TLS2_k127_3460048_0
COG0491 Zn-dependent hydrolases, including glyoxylases
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569
452.0
View
TLS2_k127_3460048_1
oxidation protein SoxZ
K17226
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000009736
267.0
View
TLS2_k127_3466777_0
PFAM LemA family
K03744
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000003116
274.0
View
TLS2_k127_3466777_1
L,D-transpeptidase catalytic domain
-
-
-
0.0000000000000000000000000000000000000000005542
163.0
View
TLS2_k127_3485101_0
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K03092
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862
591.0
View
TLS2_k127_3485101_1
Beta-lactamase
K18988
-
3.4.16.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848
451.0
View
TLS2_k127_3485101_2
ABC transporter
K06861
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363
371.0
View
TLS2_k127_3485101_3
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
K02806
GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563
-
0.0000000000000000000000000000000000000000000000000000001518
202.0
View
TLS2_k127_3485101_4
Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K05808
GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113
-
0.0000000000000000000000000000000000000000000000000000005326
201.0
View
TLS2_k127_3485101_5
3'-5' exonuclease
K03684
-
3.1.13.5
0.00000000000000000000000000000000000000001032
154.0
View
TLS2_k127_3485101_6
OstA-like protein
K09774
-
-
0.0000000000000000000000000000001007
137.0
View
TLS2_k127_3485101_7
Belongs to the small heat shock protein (HSP20) family
K04080
-
-
0.0000000000000000000000000000001381
130.0
View
TLS2_k127_3485101_8
Lipopolysaccharide-assembly, LptC-related
K11719
-
-
0.000000000000000000000000003603
121.0
View
TLS2_k127_3485101_9
Protein of unknown function (DUF1150)
-
-
-
0.000000000000000005032
87.0
View
TLS2_k127_3545925_0
Belongs to the short-chain dehydrogenases reductases (SDR) family
K07124
-
-
0.000000000000000000000000000000000000000000000000002634
194.0
View
TLS2_k127_3545925_1
Wd-40 repeat
-
-
-
0.00000000000000000000000000000000009417
143.0
View
TLS2_k127_3545925_2
YGGT family
K02221
-
-
0.0000002931
52.0
View
TLS2_k127_3547872_0
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K00286
GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
1.5.1.2
0.0000000000000000000000000000000000000000000000000000000000000000000000000000003238
273.0
View
TLS2_k127_3547872_1
transcriptional regulator
-
-
-
0.0000000000000000000000000000000000000000000001654
176.0
View
TLS2_k127_3547872_2
Signal transduction histidine kinase
K07638
-
2.7.13.3
0.00000000000000000002027
91.0
View
TLS2_k127_3547872_3
Putative bacterial sensory transduction regulator
-
-
-
0.00000000000000007102
80.0
View
TLS2_k127_3574604_0
recombinase activity
-
GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279
587.0
View
TLS2_k127_3574604_1
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K01872
-
6.1.1.7
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665
476.0
View
TLS2_k127_360842_0
COG3666 Transposase and inactivated derivatives
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579
608.0
View
TLS2_k127_360842_1
COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
-
-
-
0.000000000000000000000000000000000001464
143.0
View
TLS2_k127_360842_2
DNA methylAse
-
-
-
0.000000000001478
69.0
View
TLS2_k127_360957_0
Universal stress protein family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000005772
261.0
View
TLS2_k127_360957_1
Hydantoinase B/oxoprolinase
K01469
-
3.5.2.9
0.000000000001687
67.0
View
TLS2_k127_360957_2
Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
-
-
-
0.0004566
43.0
View
TLS2_k127_364332_0
COG0491 Zn-dependent hydrolases, including glyoxylases
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986
541.0
View
TLS2_k127_364332_1
Ankyrin repeats (3 copies)
K06867,K21440
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001892
288.0
View
TLS2_k127_364332_2
cytochrome
-
-
-
0.0000000005226
60.0
View
TLS2_k127_364332_3
AI-2E family transporter
-
-
-
0.00000006154
56.0
View
TLS2_k127_3644888_0
Oxidizes proline to glutamate for use as a carbon and nitrogen source
K13821
-
1.2.1.88,1.5.5.2
0.0
1091.0
View
TLS2_k127_36453_0
cystathionine beta-lyase
K01760
-
4.4.1.8
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192
535.0
View
TLS2_k127_36453_1
amine dehydrogenase activity
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000857
261.0
View
TLS2_k127_36453_2
ETC complex I subunit
K00329
-
1.6.5.3
0.000000002313
58.0
View
TLS2_k127_372850_0
PFAM transposase IS66
K07484
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343
536.0
View
TLS2_k127_372850_1
Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
K07484
-
-
0.0000000000000000000000000000000000000000000000000000000000338
206.0
View
TLS2_k127_372850_2
Evidence 4 Homologs of previously reported genes of
K07483
-
-
0.0000000000000000004006
91.0
View
TLS2_k127_372850_3
Transposase mutator type
-
-
-
0.0000000000000000004564
87.0
View
TLS2_k127_3746767_0
Protein of unknown function
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031
326.0
View
TLS2_k127_376437_0
Alpha-2-Macroglobulin
K06894
-
-
0.0
1306.0
View
TLS2_k127_376437_1
Beta-lactamase class C
-
-
-
0.00000000000000000000000694
102.0
View
TLS2_k127_3777561_0
Belongs to the prokaryotic GSH synthase family
K01920
GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576
6.3.2.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771
483.0
View
TLS2_k127_3777561_1
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K07056
-
2.1.1.198
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171
304.0
View
TLS2_k127_3777561_2
LppC putative lipoprotein
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000001981
255.0
View
TLS2_k127_3777561_3
SnoaL-like polyketide cyclase
K01061
-
3.1.1.45
0.0000000000000000000000000000000000000000001175
164.0
View
TLS2_k127_3777561_4
Belongs to the UPF0102 family
K07460
-
-
0.0000000000000000000000001508
111.0
View
TLS2_k127_3777561_5
Histidine kinase-like ATPases
-
-
-
0.000000000001081
73.0
View
TLS2_k127_3777561_6
2TM domain
-
-
-
0.00003793
54.0
View
TLS2_k127_3777561_7
Helix-turn-helix XRE-family like proteins
-
-
-
0.0002875
51.0
View
TLS2_k127_3777561_8
Histidine kinase
-
-
-
0.0009065
44.0
View
TLS2_k127_3788462_0
ABC 3 transport family
K02075
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214
365.0
View
TLS2_k127_3788462_1
ABC transporter
K02074
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095
309.0
View
TLS2_k127_3788462_2
Belongs to the bacterial solute-binding protein 9 family
K02077,K09815
-
-
0.0000000000000000000000000000000000000000000000000000003585
202.0
View
TLS2_k127_3788462_3
Belongs to the Fur family
K09823
-
-
0.00002848
47.0
View
TLS2_k127_3793227_0
Citrate transporter
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359
588.0
View
TLS2_k127_3793227_1
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K00053
-
1.1.1.86
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341
570.0
View
TLS2_k127_3793227_2
Predicted small integral membrane protein (DUF2165)
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000009553
228.0
View
TLS2_k127_3793227_3
Cupin
-
-
-
0.0000000000000000000000000000000000000000000000000000001705
196.0
View
TLS2_k127_3793227_4
PFAM YbaK prolyl-tRNA
K19055
-
-
0.00000000000000000000000000000000000000000000000000005117
194.0
View
TLS2_k127_3793227_5
manually curated
-
-
-
0.0000000000000000000000000000001195
126.0
View
TLS2_k127_3793227_6
acetolactate synthase
K01653
-
2.2.1.6
0.00000000000000007102
80.0
View
TLS2_k127_3793227_7
-
-
-
-
0.0000000000001285
77.0
View
TLS2_k127_3793227_8
Protein of unknown function (DUF1236)
-
-
-
0.0000005584
60.0
View
TLS2_k127_3802643_0
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K03814
-
2.4.1.129
0.00000000000000000000000000000000000000000000000000000000003733
213.0
View
TLS2_k127_3802643_1
Diguanylate cyclase
-
-
-
0.000000000000000000001909
102.0
View
TLS2_k127_3802643_2
Ribosomal L32p protein family
K02911
-
-
0.000000000000000002467
97.0
View
TLS2_k127_3810084_0
Belongs to the thiolase family
K00626
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
2.3.1.9
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152
606.0
View
TLS2_k127_3810084_1
FAD dependent oxidoreductase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104
564.0
View
TLS2_k127_3810084_10
Sulfotransferase family
-
-
-
0.00055
46.0
View
TLS2_k127_3810084_2
Acetoacetyl-CoA reductase
K00023
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
1.1.1.36
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093
332.0
View
TLS2_k127_3810084_3
Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K01069
-
3.1.2.6
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841
320.0
View
TLS2_k127_3810084_4
Methyltransferase domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000743
279.0
View
TLS2_k127_3810084_5
synthesis repressor PhaR
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000714
225.0
View
TLS2_k127_3810084_6
GntR family
K13637
-
-
0.0000000000000000000000000000000000000000000000000000000003357
211.0
View
TLS2_k127_3810084_7
Cupin superfamily (DUF985)
K09705
-
-
0.0000000000000000000000000000000000000000000000002716
193.0
View
TLS2_k127_3810084_8
methionine biosynthesis protein (MetW)
-
-
-
0.0000000000000000000000000001675
115.0
View
TLS2_k127_3810084_9
Transposase DDE domain
-
-
-
0.00000002551
64.0
View
TLS2_k127_3827310_0
NMT1/THI5 like
K02051
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331
344.0
View
TLS2_k127_3827310_1
PFAM response regulator receiver
K07665
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006107
280.0
View
TLS2_k127_3827310_2
Binding-protein-dependent transport system inner membrane component
K02050
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000007551
278.0
View
TLS2_k127_3827310_3
Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000002284
264.0
View
TLS2_k127_3836178_0
Tripartite ATP-independent periplasmic transporter, DctM component
-
-
-
3.973e-217
680.0
View
TLS2_k127_3836178_1
COG4663 TRAP-type mannitol chloroaromatic compound transport system, periplasmic component
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367
582.0
View
TLS2_k127_3836178_2
Glutamine synthetase, catalytic domain
K01915
-
6.3.1.2
0.0000000000000000000000000000000000000000006421
158.0
View
TLS2_k127_3836178_3
Tripartite ATP-independent periplasmic transporters, DctQ component
-
-
-
0.0000000000000000000002858
98.0
View
TLS2_k127_3837849_0
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K01255
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
3.4.11.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386
588.0
View
TLS2_k127_3837849_1
permease YjgP YjgQ family protein
K07091
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484
300.0
View
TLS2_k127_3837849_2
Nucleoside triphosphate pyrophosphohydrolase
K02499,K04765
GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658
3.6.1.9
0.00000000000000000000000000000000000000000000000000000000004062
210.0
View
TLS2_k127_3853550_0
Calcineurin-like phosphoesterase
K07313
-
3.1.3.16
0.000000000000000000000000000000000000000000000000000000000000000000009325
242.0
View
TLS2_k127_3853550_1
Protein of unknown function (DUF1134)
-
-
-
0.00000000000000000000000000000000008913
134.0
View
TLS2_k127_3853550_2
motor activity
-
-
-
0.00000000000000002236
94.0
View
TLS2_k127_3859537_0
Substrate binding domain of ABC-type glycine betaine transport system
K02002
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335
543.0
View
TLS2_k127_3859537_1
ATPases associated with a variety of cellular activities
K02000
-
3.6.3.32
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598
449.0
View
TLS2_k127_3861437_0
Conserved region in glutamate synthase
K22083
-
2.1.1.21
1.841e-264
821.0
View
TLS2_k127_3861437_1
COG0004 Ammonia permease
-
-
-
2.76e-231
721.0
View
TLS2_k127_3861437_2
Glutamine synthetase, catalytic domain
K01915,K01949
-
6.3.1.2,6.3.4.12
3.812e-208
654.0
View
TLS2_k127_3861437_3
COG0070 Glutamate synthase domain 3
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168
348.0
View
TLS2_k127_3861437_4
-
-
-
-
0.00000000000000000000000000000000000000000000000000000001105
211.0
View
TLS2_k127_3861437_5
-
-
-
-
0.00000000000000000000000000000000008799
140.0
View
TLS2_k127_3861437_6
-
-
-
-
0.000000000000007397
77.0
View
TLS2_k127_3881445_0
Diguanylate cyclase phosphodiesterase with PAS PAC
K13245
-
3.1.4.52
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564
519.0
View
TLS2_k127_3881445_1
Belongs to the peptidase M16 family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971
308.0
View
TLS2_k127_3881445_2
Acetyltransferases, including N-acetylases of ribosomal proteins
K03790
-
2.3.1.128
0.000000000000000000000000000000000000000000000000000000000000000000000000001014
258.0
View
TLS2_k127_3887802_0
Tetratricopeptide repeat
K03671,K05838
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931
353.0
View
TLS2_k127_3887802_1
YbaK prolyl-tRNA synthetase associated
K19055
-
-
0.000000000000000000000000000000000609
133.0
View
TLS2_k127_3887802_2
peptidase S16
K01338,K07157
-
3.4.21.53
0.00000000000000006382
83.0
View
TLS2_k127_3890241_0
Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
K03455,K11747
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661
536.0
View
TLS2_k127_3890241_1
Sigma-70, region 4
K03089
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588
460.0
View
TLS2_k127_3890241_2
Alpha beta hydrolase
-
-
-
0.000000000000000000000000000000000000001188
160.0
View
TLS2_k127_3890241_3
Responsible for synthesis of pseudouridine from uracil
K06180
GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360
5.4.99.23
0.0000002018
53.0
View
TLS2_k127_3892150_0
In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K00951,K01139
-
2.7.6.5,3.1.7.2
9.266e-307
954.0
View
TLS2_k127_3892150_1
Peptidase S24-like
K03100
-
3.4.21.89
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136
361.0
View
TLS2_k127_3892150_2
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K03474
-
2.6.99.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075
330.0
View
TLS2_k127_3892150_3
Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
K03685
GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363
3.1.26.3
0.0000000000000000000000000000000000000000000000000000000000000000001927
236.0
View
TLS2_k127_3892150_4
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
K00997
-
2.7.8.7
0.00000000000000000000000000000000000000000000000000000005153
201.0
View
TLS2_k127_3892150_5
Protein conserved in bacteria
K09928
-
-
0.00000000000000000000000000000000000000000000002358
178.0
View
TLS2_k127_3892150_6
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K03595
-
-
0.00000000000000000000000135
110.0
View
TLS2_k127_3892172_0
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K01866
GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564
6.1.1.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693
602.0
View
TLS2_k127_3892172_1
Protein of unknown function
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905
477.0
View
TLS2_k127_3892172_2
Uncharacterized protein family (UPF0051)
K09014
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018
410.0
View
TLS2_k127_3892172_3
X-Pro dipeptidyl-peptidase (S15 family)
K07018
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007971
358.0
View
TLS2_k127_3892172_4
COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
K04487
-
2.8.1.7
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797
363.0
View
TLS2_k127_3894280_0
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
K09458
GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576
2.3.1.179
1.819e-220
690.0
View
TLS2_k127_3894280_1
Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K07082
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003
407.0
View
TLS2_k127_3894280_2
Acyl-carrier-protein S-malonyltransferase
K00645
GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576
2.3.1.39
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594
392.0
View
TLS2_k127_3894280_3
PFAM short-chain dehydrogenase reductase SDR
K00059
GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576
1.1.1.100
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225
367.0
View
TLS2_k127_3894280_4
Phosphopantetheine attachment site
K02078
GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509
-
0.000000000000000000000000000000000000009884
145.0
View
TLS2_k127_3894280_5
Domain of unknown function (DUF1732)
-
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464
-
0.00000000000000000004282
100.0
View
TLS2_k127_3896321_0
Belongs to the short-chain dehydrogenases reductases (SDR) family
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879
341.0
View
TLS2_k127_3896321_1
Pyrrolo-quinoline quinone
-
-
-
0.00000000000000001231
89.0
View
TLS2_k127_3896321_2
OsmC-like protein
-
-
-
0.0000000005157
63.0
View
TLS2_k127_3896321_3
-
-
-
-
0.000001052
51.0
View
TLS2_k127_3901437_0
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
K00606
-
2.1.2.11
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362
407.0
View
TLS2_k127_3901437_1
NnrU protein
-
-
-
0.0000000000000000000000000000000000000000000000000000000001313
208.0
View
TLS2_k127_3901437_2
Tetratricopeptide repeat-like domain
-
-
-
0.00000000000000000000000000000000000000000001471
169.0
View
TLS2_k127_3902087_0
Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K00831
-
2.6.1.52
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254
559.0
View
TLS2_k127_3902087_1
Opacity protein and related surface antigens
-
-
-
0.0000000000000000000000000000000000000000000000003047
182.0
View
TLS2_k127_3902087_2
Opacity protein and related surface antigens
-
-
-
0.000000000008587
68.0
View
TLS2_k127_3909273_0
ankyrin repeat
K06867,K08738,K21440
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849
575.0
View
TLS2_k127_3909273_1
-
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000595
275.0
View
TLS2_k127_3909273_2
Cytochrome C oxidase, cbb3-type, subunit III
-
-
-
0.000000000000000000000000000000000000000000000004868
178.0
View
TLS2_k127_3909273_3
PQQ-like domain
-
-
-
0.0000000000000000000008381
95.0
View
TLS2_k127_3909273_4
Periplasmic binding protein
-
-
-
0.00005735
51.0
View
TLS2_k127_3919552_0
fructose-bisphosphate aldolase
K01623
-
4.1.2.13
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937
517.0
View
TLS2_k127_3919552_1
Patatin-like phospholipase
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325
388.0
View
TLS2_k127_3919552_2
Protein of unknown function (DUF2950)
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000003137
236.0
View
TLS2_k127_3919552_3
Nitroreductase family
-
-
-
0.0000000000000000000000000000000000000000000002198
171.0
View
TLS2_k127_3919552_4
Protein of unknown function (DUF2950)
-
-
-
0.0000000000000000000000003298
109.0
View
TLS2_k127_393225_0
CoA binding domain
K09181
-
-
9.39e-304
956.0
View
TLS2_k127_393225_1
COG0477 Permeases of the major facilitator superfamily
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359
596.0
View
TLS2_k127_393225_2
Histidine kinase
K14986
-
2.7.13.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597
513.0
View
TLS2_k127_393225_3
helix_turn_helix, Lux Regulon
K14987
-
-
0.0000000000000000000000000000000000000000000000000000000000000000001995
239.0
View
TLS2_k127_393225_4
helix_turn_helix, cAMP Regulatory protein
K01420,K15861
-
-
0.0000000000000000000000000000000000000000000000006601
183.0
View
TLS2_k127_393225_5
LapD/MoxY periplasmic domain
K07675
-
2.7.13.3
0.0000000000000000000000000000000000000000000007344
174.0
View
TLS2_k127_393225_6
Protein required for attachment to host cells
-
-
-
0.00000000000000000000000000007845
123.0
View
TLS2_k127_393225_7
Cytochrome c
-
GO:0005575,GO:0005623,GO:0042597,GO:0044464
-
0.000000000000005747
79.0
View
TLS2_k127_3943502_0
Tetratricopeptide repeat
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912
577.0
View
TLS2_k127_3943502_1
Belongs to the FPP GGPP synthase family
K02523
GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663
2.5.1.90
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355
456.0
View
TLS2_k127_3943502_2
Methyltransferase small domain
K15460
-
2.1.1.223
0.000000000000000000000000000000000000000000000000000000000000000000273
238.0
View
TLS2_k127_3943502_3
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K00919
GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515
2.7.1.148
0.000000000000000000000000000000000000000000000000000000000000000004078
241.0
View
TLS2_k127_3943502_4
Putative prokaryotic signal transducing protein
-
-
-
0.0000000000000000002253
91.0
View
TLS2_k127_3963465_0
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
K03495
GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363
-
3.413e-285
887.0
View
TLS2_k127_3963465_1
Cellulose biosynthesis protein BcsQ
K03496
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513
366.0
View
TLS2_k127_3963465_2
Belongs to the ParB family
K03497
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002605
297.0
View
TLS2_k127_3963465_3
DNA polymerase III, delta subunit
K02340
-
2.7.7.7
0.000000000000000000000000000000000000000000000000000000000000000000000000005283
266.0
View
TLS2_k127_3963465_4
Phosphoribosyl transferase domain
K00762
-
2.4.2.10
0.000000000000000000000000000000000000000000000000000000000000001123
233.0
View
TLS2_k127_3963465_5
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA
K03501
GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360
2.1.1.170
0.000000000000000000000000000000000000000000000000000000000323
209.0
View
TLS2_k127_3963465_6
Lipopolysaccharide-assembly
K03643
-
-
0.000000000000000000000000000000000000004667
152.0
View
TLS2_k127_3963465_7
Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K03650
-
-
0.00000000000000000000000000001648
123.0
View
TLS2_k127_3963465_8
Belongs to the class-I aminoacyl-tRNA synthetase family
K01869
GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576
6.1.1.4
0.00000004781
54.0
View
TLS2_k127_3964684_0
Alpha beta hydrolase fold
K01048
-
3.1.1.5
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691
332.0
View
TLS2_k127_3964684_1
PFAM Inositol monophosphatase
K01092,K18649
-
3.1.3.15,3.1.3.25,3.1.3.93
0.00000000000000000000000000000000000000000000000000000000000000000000001483
246.0
View
TLS2_k127_3964684_2
Belongs to the small heat shock protein (HSP20) family
K04080
-
-
0.000000000000000000000000000000000000000000000000000000001398
206.0
View
TLS2_k127_3985577_0
Protein-glutamate methylesterase
K13924
-
2.1.1.80,3.1.1.61
0.0
1674.0
View
TLS2_k127_3985577_1
Hsp20/alpha crystallin family
K04080
-
-
0.0000000000000000000000000000000000000000000000000129
184.0
View
TLS2_k127_3985577_2
Transposase
-
-
-
0.000000000000000000000000000000000000000000000006852
188.0
View
TLS2_k127_3985577_3
Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
-
-
-
0.00000000000000000001093
103.0
View
TLS2_k127_3985577_5
Response regulator, receiver
-
-
-
0.00000000008138
63.0
View
TLS2_k127_3985577_6
IS66 C-terminal element
-
-
-
0.0002776
53.0
View
TLS2_k127_3990940_0
Pyridine nucleotide-disulphide oxidoreductase
K00384
-
1.8.1.9
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123
531.0
View
TLS2_k127_3990940_1
Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
K03282
-
-
0.0000000000000000000000000000000000000000000002628
171.0
View
TLS2_k127_3990940_2
2Fe-2S iron-sulfur cluster binding domain
K04755
-
-
0.00000000000000000000000000000000000149
140.0
View
TLS2_k127_400602_0
Glycyl-tRNA synthetase beta subunit
K01879
-
6.1.1.14
2.59e-207
657.0
View
TLS2_k127_400602_1
Belongs to the PEP-utilizing enzyme family
K01006
-
2.7.9.1
0.00000000000000000000000000000000000000003737
155.0
View
TLS2_k127_400602_2
Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
K07032
-
-
0.000000000000000000000000000000000000008714
149.0
View
TLS2_k127_400602_3
Gamma-glutamyl cyclotransferase, AIG2-like
-
-
-
0.0000000000000000001652
94.0
View
TLS2_k127_4019465_0
ABC-type Fe3 transport system, periplasmic component
K02012
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677
479.0
View
TLS2_k127_4019465_1
-
-
-
-
0.00000000000000000000000000000000000001525
151.0
View
TLS2_k127_4019465_2
PFAM ATP-binding region ATPase domain protein
-
-
-
0.0000000000000000000000000000000000001437
145.0
View
TLS2_k127_4019465_3
Binding-protein-dependent transport system inner membrane component
K02011
-
-
0.0000000000000000000000000002499
118.0
View
TLS2_k127_4019793_0
Formylmethanofuran dehydrogenase subunit A
K00200
-
1.2.7.12
3.776e-262
817.0
View
TLS2_k127_4019793_1
Formylmethanofuran dehydrogenase, subunit B
K00201
-
1.2.7.12
0.000000000000000000000000000000000000000000000000000000000000000000000000000008822
265.0
View
TLS2_k127_4030206_0
Enoyl-(Acyl carrier protein) reductase
K00059
-
1.1.1.100
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625
323.0
View
TLS2_k127_4030206_1
Bacterial regulatory proteins, tetR family
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000005922
242.0
View
TLS2_k127_4030206_2
Large extracellular alpha-helical protein
-
-
-
0.000000000000009964
81.0
View
TLS2_k127_4030206_3
Belongs to the pirin family
K06911
-
-
0.0000000000000128
73.0
View
TLS2_k127_4030206_4
pyrroloquinoline quinone binding
-
-
-
0.00000000007479
70.0
View
TLS2_k127_4058032_0
Methylmalonyl-CoA mutase
K01847
-
5.4.99.2
2.592e-295
914.0
View
TLS2_k127_4058032_1
ArgK protein
K07588
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263
360.0
View
TLS2_k127_4064194_0
Metallo-beta-lactamase superfamily
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284
351.0
View
TLS2_k127_4064194_1
phosphatase homologous to the C-terminal domain of histone macroH2A1
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000001787
225.0
View
TLS2_k127_4064194_2
COG2207 AraC-type DNA-binding domain-containing proteins
-
-
-
0.0000000000000000000000000000000000000000000000108
177.0
View
TLS2_k127_4064194_3
Cytochrome bd terminal oxidase subunit I
K00425
-
1.10.3.14
0.000000000000000000000000000000000000000000005891
166.0
View
TLS2_k127_4064194_4
Helix-turn-helix domain
-
-
-
0.000000000000000000000000000000009568
130.0
View
TLS2_k127_4064194_5
Metallo-beta-lactamase superfamily
-
-
-
0.00000000000000000000001044
102.0
View
TLS2_k127_4064194_6
Cytochrome C oxidase, cbb3-type, subunit III
-
-
-
0.00000000001647
65.0
View
TLS2_k127_4076697_0
NMT1-like family
K07080
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001102
295.0
View
TLS2_k127_4096249_0
Serine carboxypeptidase
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751
516.0
View
TLS2_k127_4096249_1
Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K14393
-
-
0.0004646
47.0
View
TLS2_k127_4170219_0
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K01736
GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576
4.2.3.5
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661
592.0
View
TLS2_k127_4170219_1
FtsJ-like methyltransferase
K06442
-
2.1.1.226,2.1.1.227
0.0000000000000000000000000000000000000000000000000000000000000000000000000000001664
272.0
View
TLS2_k127_4170221_0
Belongs to the ALAD family
K01698
GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
4.2.1.24
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437
464.0
View
TLS2_k127_4170221_1
May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
K21420
GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575
2.3.2.29
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001986
282.0
View
TLS2_k127_4170221_2
Enoyl-CoA hydratase/isomerase
K01692,K05605
-
3.1.2.4,4.2.1.17
0.000000000000000000000000000000000000000000000000000000000000000000000000000000005651
283.0
View
TLS2_k127_4170221_3
Transcriptional regulator
-
-
-
0.000000000000000000000000000000000000000000000000000000001263
203.0
View
TLS2_k127_4170221_4
Extensin family
-
-
-
0.0000000000000000000000000000000000000000000000000754
191.0
View
TLS2_k127_4170221_5
RDD family
-
-
-
0.00000000000000000000000000000000000000664
150.0
View
TLS2_k127_4209054_0
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K00283
-
1.4.4.2
1.2e-248
775.0
View
TLS2_k127_4209054_1
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K00282
-
1.4.4.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596
433.0
View
TLS2_k127_4209054_2
4-amino-4-deoxy-L-arabinose transferase activity
-
-
-
0.000000000000000000000000000000000000000000000000000000000001925
219.0
View
TLS2_k127_4268223_0
PFAM MOFRL domain protein
K11529
-
2.7.1.165
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447
605.0
View
TLS2_k127_4268223_1
Formate--tetrahydrofolate ligase
K01938
-
6.3.4.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597
596.0
View
TLS2_k127_4347267_0
Branched-chain amino acid transport system / permease component
K01997
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476
387.0
View
TLS2_k127_4347267_1
Belongs to the binding-protein-dependent transport system permease family
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557
389.0
View
TLS2_k127_4347267_2
ATPases associated with a variety of cellular activities
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491
331.0
View
TLS2_k127_4347267_3
Branched-chain amino acid ATP-binding cassette transporter
K01995
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758
312.0
View
TLS2_k127_4347267_4
Nitroreductase family
K04719
GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016491,GO:0016705,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
1.13.11.79
0.000000000000000000000000000000000000000000000000000029
190.0
View
TLS2_k127_4347267_5
-
-
-
-
0.00000000000000001093
91.0
View
TLS2_k127_440261_0
exporters of the RND superfamily
K07003
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601
424.0
View
TLS2_k127_440261_1
PQQ-like domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000007568
285.0
View
TLS2_k127_440261_2
Periplasmic or secreted lipoprotein
-
-
-
0.00000000000000000000000000000008277
130.0
View
TLS2_k127_4415684_0
peptidyl-tyrosine sulfation
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352
563.0
View
TLS2_k127_4415684_1
Tetratricopeptide TPR_2 repeat protein
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195
379.0
View
TLS2_k127_4415684_10
efflux transmembrane transporter activity
-
-
-
0.00000000000000000000000000000000000000002912
167.0
View
TLS2_k127_4415684_11
Major Facilitator Superfamily
-
-
-
0.000000000000000000000000000000000001822
151.0
View
TLS2_k127_4415684_12
efflux transmembrane transporter activity
-
-
-
0.0000000000000000000000000000000015
144.0
View
TLS2_k127_4415684_13
Transcriptional regulator
-
-
-
0.0000000000000000000000000000198
127.0
View
TLS2_k127_4415684_14
-
-
-
-
0.00000000000000000000569
92.0
View
TLS2_k127_4415684_15
Helix-hairpin-helix motif
K02237
-
-
0.000000000000000008809
83.0
View
TLS2_k127_4415684_16
MacB-like periplasmic core domain
-
-
-
0.0007856
46.0
View
TLS2_k127_4415684_2
Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K01714
-
4.3.3.7
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687
360.0
View
TLS2_k127_4415684_3
Enolase C-terminal domain-like
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172
288.0
View
TLS2_k127_4415684_4
PFAM Major Facilitator Superfamily
K08191
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000009122
272.0
View
TLS2_k127_4415684_5
domain, Protein
K20276
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000001509
284.0
View
TLS2_k127_4415684_6
COG3119 Arylsulfatase A
K01138
-
-
0.000000000000000000000000000000000000000000000000000000000002303
211.0
View
TLS2_k127_4415684_7
Tetratricopeptide repeat
-
-
-
0.00000000000000000000000000000000000000000000000000000000004412
218.0
View
TLS2_k127_4415684_8
Protein of unknown function (DUF1501)
-
-
-
0.0000000000000000000000000000000000000000000000000006615
204.0
View
TLS2_k127_4415684_9
PFAM Formylglycine-generating sulfatase enzyme
-
-
-
0.00000000000000000000000000000000000000000000000002707
193.0
View
TLS2_k127_4433659_0
Carboxyl transferase domain
K01966
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575
2.1.3.15,6.4.1.3
0.00000000000000000000000000000000000000000000004104
169.0
View
TLS2_k127_4433659_1
Mechanosensitive ion channel
-
-
-
0.00000000000000000000000000000000000000000607
160.0
View
TLS2_k127_4433659_3
Cytochrome c
-
-
-
0.0000000000000000008978
89.0
View
TLS2_k127_4482410_0
Amino acid regulated cytosolic protein
K06918
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828
437.0
View
TLS2_k127_4482410_1
Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
K08641
-
3.4.13.22
0.000000000000000000000000000000000000000000000000000000000000002329
227.0
View
TLS2_k127_4482410_2
Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K06204
-
-
0.000000000000000000000000000000000000000000000000000000000000007926
222.0
View
TLS2_k127_4572045_0
lipid A ABC exporter family, fused ATPase and inner membrane subunits
K06147
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318
577.0
View
TLS2_k127_4572045_1
Protein of unknown function (DUF861)
-
-
-
0.000000000000000000000003647
101.0
View
TLS2_k127_4677733_0
Glutamine amidotransferase domain
K22081
-
2.1.1.21
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548
408.0
View
TLS2_k127_4677733_1
Transcriptional
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002282
280.0
View
TLS2_k127_4677733_2
GXGXG motif
K22082
-
2.1.1.21
0.000000000000000000000000000000000000000000000000000000000000000000000000008592
253.0
View
TLS2_k127_4677733_3
helix-turn-helix- domain containing protein AraC type
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000002676
225.0
View
TLS2_k127_4677733_4
-
-
-
-
0.0000001968
55.0
View
TLS2_k127_4683410_0
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K07568
GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659
2.4.99.17
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975
467.0
View
TLS2_k127_4683410_1
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K03767,K03768
-
5.2.1.8
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995
297.0
View
TLS2_k127_4683410_2
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K01802,K09565
-
5.2.1.8
0.0000000000000000000000000000000000000000000000000000000000000000000000003363
251.0
View
TLS2_k127_4683410_3
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
K00773
-
2.4.2.29
0.0000000000000000000000000000000000000000000000000000000000000000001063
234.0
View
TLS2_k127_4683410_4
Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K00954
-
2.7.7.3
0.000000000000000000000000000000000000000000000000000000000009314
211.0
View
TLS2_k127_4690981_0
Belongs to the aldehyde dehydrogenase family
K00128,K09472
-
1.2.1.3,1.2.1.99
6.339e-257
799.0
View
TLS2_k127_4690981_1
Belongs to the aldehyde dehydrogenase family
K00135,K15786
-
1.2.1.16,1.2.1.20,1.2.1.79
2.345e-238
744.0
View
TLS2_k127_4690981_2
Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
K02052,K11072,K11076
-
3.6.3.31
1.507e-195
626.0
View
TLS2_k127_4690981_3
Required for the activity of the bacterial periplasmic transport system of putrescine
K11069
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641
567.0
View
TLS2_k127_4690981_4
putrescine
K11071
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665
475.0
View
TLS2_k127_4690981_5
Binding-protein-dependent transport system inner membrane component
K11070
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438
433.0
View
TLS2_k127_4690981_6
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K00822,K00833
-
2.6.1.18,2.6.1.62
0.000000000000000000000000001317
123.0
View
TLS2_k127_4690981_7
Glutamine synthetase, catalytic domain
K01915
GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0034024,GO:0034641,GO:0042402,GO:0044106,GO:0044237,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575
6.3.1.2
0.0000000000000000002851
87.0
View
TLS2_k127_4694384_0
Arginase family
K01480
-
3.5.3.11
4.158e-233
725.0
View
TLS2_k127_4694384_1
Protein of unknown function (DUF1116)
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972
517.0
View
TLS2_k127_4694384_10
Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A
K02228
-
2.1.1.152
0.000000000000000000505
87.0
View
TLS2_k127_4694384_11
-
-
-
-
0.00000000000001005
82.0
View
TLS2_k127_4694384_2
Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K00641
-
2.3.1.31
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429
437.0
View
TLS2_k127_4694384_3
Glutamine amidotransferase class-I
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969
311.0
View
TLS2_k127_4694384_4
Flavodoxin-like fold
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458
302.0
View
TLS2_k127_4694384_5
transcriptional regulator
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000006424
255.0
View
TLS2_k127_4694384_6
HupE / UreJ protein
K03192
-
-
0.0000000000000000000000000000000000000000000000000000000000000000001882
236.0
View
TLS2_k127_4694384_7
glutamine synthetase
K01915
-
6.3.1.2
0.000000000000000000000000000000000000001505
154.0
View
TLS2_k127_4694384_8
Bacterial regulatory proteins, tetR family
-
-
-
0.00000000000000000000000000000000000001055
154.0
View
TLS2_k127_4694384_9
COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
-
-
-
0.000000000000000000000000000000000007774
148.0
View
TLS2_k127_4696277_0
Amidohydrolase family
K01465
-
3.5.2.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546
580.0
View
TLS2_k127_4696277_1
belongs to the nudix hydrolase family
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317
431.0
View
TLS2_k127_4696277_10
COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component
K07323
-
-
0.00000003409
63.0
View
TLS2_k127_4696277_2
glycosylase i
K01246
-
3.2.2.20
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456
304.0
View
TLS2_k127_4696277_3
Metal dependent phosphohydrolases with conserved 'HD' motif.
K06952
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000118
267.0
View
TLS2_k127_4696277_4
MacB-like periplasmic core domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000008507
274.0
View
TLS2_k127_4696277_5
Belongs to the GcvT family
K06980
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000003167
265.0
View
TLS2_k127_4696277_6
ABC transporter
K02003,K09810
-
-
0.00000000000000000000000000000000000000000000000000000000000000004352
230.0
View
TLS2_k127_4696277_7
protein tyrosine phosphatase
-
-
-
0.00000000000000000000000000000000000000000000000001548
186.0
View
TLS2_k127_4696277_8
Dehydrogenase
K21430
-
-
0.0000000000000000000000000001428
118.0
View
TLS2_k127_4696277_9
Uncharacterized protein conserved in bacteria (DUF2188)
-
-
-
0.00000000000000007318
83.0
View
TLS2_k127_4710568_0
The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
K00325
GO:0008150,GO:0008152,GO:0055114
1.6.1.2
1.72e-214
672.0
View
TLS2_k127_4710568_1
Alpha/beta hydrolase family
K06889
-
-
0.000000000000000000000000000000000000000000000000000000000000009958
225.0
View
TLS2_k127_4710568_2
Haloacid dehalogenase-like hydrolase
K01560
-
3.8.1.2
0.000000000000000000000000000000000000000000000000000000000000339
220.0
View
TLS2_k127_4710568_3
Haloacid dehalogenase-like hydrolase
K01560
-
3.8.1.2
0.0000000000000000000000000000009116
124.0
View
TLS2_k127_4712331_0
depolymerase
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000003556
265.0
View
TLS2_k127_4712331_1
Putative cyclase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000998
249.0
View
TLS2_k127_4712331_2
acetyltransferase
-
-
-
0.00000000000000000000000000002418
122.0
View
TLS2_k127_471411_0
unusual protein kinase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087
439.0
View
TLS2_k127_471411_1
SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains.
K13449,K20412
-
-
0.000000000000000001945
94.0
View
TLS2_k127_4719640_0
Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K05896
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988
297.0
View
TLS2_k127_4719640_1
Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K06024
-
-
0.000000000000000000000000000000000000000000000000000000003344
204.0
View
TLS2_k127_4719640_2
Glycosyl hydrolase family 3 N terminal domain
K01207,K05349
-
3.2.1.21,3.2.1.52
0.0000000000000000000000000000000008997
134.0
View
TLS2_k127_4722884_0
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K03040
GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576
2.7.7.6
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997
587.0
View
TLS2_k127_4722884_1
The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
K03076
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526
417.0
View
TLS2_k127_4722884_2
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
K00939
-
2.7.4.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000002512
273.0
View
TLS2_k127_4722884_3
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K02948
GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.0000000000000000000000000000000000000000000000000000000000000000009075
228.0
View
TLS2_k127_4722884_4
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K02952
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000000000000000000000000000000000000000521
213.0
View
TLS2_k127_4722884_5
Ribosomal protein L17
K02879
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904
-
0.00000000000000000000000000000000000000000000000000000000003744
207.0
View
TLS2_k127_4722884_6
Polyketide cyclase / dehydrase and lipid transport
-
-
-
0.000000000000000000000000000000000005672
142.0
View
TLS2_k127_4740739_0
Acetyltransferase (GNAT) domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000001403
233.0
View
TLS2_k127_4740739_1
Reversible hydration of carbon dioxide
K01673
-
4.2.1.1
0.00000000000000000000000000000000000000000000000000000002057
203.0
View
TLS2_k127_4740739_2
Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K00133
-
1.2.1.11
0.0000000000000000000000000000000000000000000001141
169.0
View
TLS2_k127_4741177_0
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K03218
-
2.1.1.185
0.000000000000000000000000000000000000000000000000000000004877
203.0
View
TLS2_k127_4749665_0
An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
K01961
GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576
6.3.4.14,6.4.1.2
9.963e-224
700.0
View
TLS2_k127_4749665_1
Peptidase family M48
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312
418.0
View
TLS2_k127_4749665_2
Aminotransferase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521
385.0
View
TLS2_k127_4749665_3
DSBA-like thioredoxin domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000000001152
227.0
View
TLS2_k127_4749665_4
Catalyzes a trans-dehydration via an enolate intermediate
K03786
-
4.2.1.10
0.000000000000000000000000000000000000000000000000000000000003165
212.0
View
TLS2_k127_4749665_5
Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs
K08300
-
3.1.26.12
0.000000000000000000000000000000000000000000000000000000000007933
220.0
View
TLS2_k127_4749665_6
first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
K02160
GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576
-
0.0000000000000000000000000000000000000000000000005325
180.0
View
TLS2_k127_475826_0
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K01599
-
4.1.1.37
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572
407.0
View
TLS2_k127_475826_1
membrane
K08973
-
-
0.0000000000000000000000000000000000000000000000000006909
186.0
View
TLS2_k127_475826_2
Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
K09773
-
2.7.11.33,2.7.4.28
0.00000000000000000000000000000000000006105
145.0
View
TLS2_k127_4762797_0
glutamine synthetase
K01915
-
6.3.1.2
2.301e-233
731.0
View
TLS2_k127_4762797_1
Belongs to the P(II) protein family
K04751
GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772
-
0.00000000000000000000000000000000000000000000000000000000004093
206.0
View
TLS2_k127_4777271_0
Glutathione S-transferase, N-terminal domain
K00799
-
2.5.1.18
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173
307.0
View
TLS2_k127_4777271_1
Protein of unknown function (DUF3175)
-
-
-
0.00000000000000000000000000000483
123.0
View
TLS2_k127_4777271_2
-
-
-
-
0.0000000000000000000000000004128
120.0
View
TLS2_k127_4779073_0
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K01356
GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141
3.4.21.88
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332
361.0
View
TLS2_k127_4779073_1
Domain of unknown function (DUF4131)
K02238
-
-
0.0000000000000000000000000000000000000000000000001588
186.0
View
TLS2_k127_4779073_2
Competence protein
K02238
-
-
0.000000000000000000000001059
115.0
View
TLS2_k127_4783457_0
Elongation factor G C-terminus
K06207
GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840
-
0.00000000000000000000000000000000000000000000000000001404
189.0
View
TLS2_k127_4783457_1
FR47-like protein
-
-
-
0.00000000000000000000000000000000000000000000000000008002
192.0
View
TLS2_k127_4794369_0
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K03798
-
-
4.335e-236
736.0
View
TLS2_k127_4794369_1
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
K04075
-
6.3.4.19
0.00000072
56.0
View
TLS2_k127_4811549_0
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K00283
-
1.4.4.2
3.409e-249
777.0
View
TLS2_k127_4811549_1
4-amino-4-deoxy-L-arabinose transferase activity
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000004084
232.0
View
TLS2_k127_4815288_0
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K01338
-
3.4.21.53
0.0
1213.0
View
TLS2_k127_4815288_1
ClpX C4-type zinc finger
K03544
GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575
-
9.253e-238
738.0
View
TLS2_k127_4815288_2
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K00331
GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114
1.6.5.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858
333.0
View
TLS2_k127_4815288_3
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K00332
GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114
1.6.5.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001972
298.0
View
TLS2_k127_4815288_4
Thioesterase
K18700
-
3.1.2.29
0.00000000000000000000000000000000000000000000000000001748
193.0
View
TLS2_k127_4815288_5
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
K03530
-
-
0.00000000000000000000000003212
109.0
View
TLS2_k127_4815288_7
Caspase domain
-
-
-
0.0000001305
62.0
View
TLS2_k127_4815288_8
-
-
-
-
0.00004342
47.0
View
TLS2_k127_4820524_0
Transport of potassium into the cell
K03549
GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662
-
1.204e-257
808.0
View
TLS2_k127_4820524_1
Belongs to the peptidase S1C family
K04771
GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564
3.4.21.107
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334
572.0
View
TLS2_k127_4820524_2
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K00791
GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360
2.5.1.75
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937
321.0
View
TLS2_k127_4820524_3
HflC and HflK could regulate a protease
K04087
-
-
0.00000000000000000000000000000000000000000000000000000011
200.0
View
TLS2_k127_4820524_4
Protein conserved in bacteria
K09937
-
-
0.0000000000001855
71.0
View
TLS2_k127_4833680_0
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
K03070
GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680
-
1.945e-226
713.0
View
TLS2_k127_4833680_1
ErfK YbiS YcfS YnhG family protein
-
-
-
0.0000000000000000000000000000000000000000000000000001704
188.0
View
TLS2_k127_4845139_0
damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
K03702
-
-
1.252e-243
760.0
View
TLS2_k127_4845139_1
ATP dependent DNA ligase domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000422
294.0
View
TLS2_k127_4845139_2
ATP dependent DNA ligase domain
-
-
-
0.000000000000000445
89.0
View
TLS2_k127_4848288_0
HNH endonuclease
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006237
345.0
View
TLS2_k127_4848288_1
SNARE associated Golgi protein
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000001345
275.0
View
TLS2_k127_4848288_2
Disulfide bond formation protein DsbB
K03611
-
-
0.00000000000000000000000000000000000004003
151.0
View
TLS2_k127_4848288_3
PFAM aldo keto reductase
-
-
-
0.00000000000000003831
84.0
View
TLS2_k127_4856274_0
Acts as a magnesium transporter
K06213
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794
404.0
View
TLS2_k127_4870532_0
COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
K00344
GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003960,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016651,GO:0016655,GO:0017091,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:1901363
1.6.5.5
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494
464.0
View
TLS2_k127_4870532_1
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K02434
GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564
6.3.5.6,6.3.5.7
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522
293.0
View
TLS2_k127_4870584_0
MltA specific insert domain
K08304
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749
326.0
View
TLS2_k127_4870584_1
PFAM Smr protein MutS2
-
-
-
0.0000000000000000000000000000001183
131.0
View
TLS2_k127_4870692_0
Zincin-like metallopeptidase
K00930
-
2.7.2.8
0.0000000000000000000000000000000000000000000000000008618
187.0
View
TLS2_k127_4870692_1
-
-
-
-
0.000000000000000000002222
102.0
View
TLS2_k127_4870692_2
-
-
-
-
0.000000000153
69.0
View
TLS2_k127_4892905_0
Glycosyl transferase family 21
K00694,K01210
-
2.4.1.12,3.2.1.58
9.35e-321
1005.0
View
TLS2_k127_4892905_1
beta (1-6) glucans synthase
K01210
-
3.2.1.58
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177
446.0
View
TLS2_k127_4892905_2
heavy metal translocating P-type ATPase
K17686
-
3.6.3.54
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379
372.0
View
TLS2_k127_4892905_3
Activator of Hsp90 ATPase
-
-
-
0.000000000000000000000000000000000000000000000000000000001577
205.0
View
TLS2_k127_4892905_4
helix_turn_helix, Arsenical Resistance Operon Repressor
-
-
-
0.0000000000000000000000000000000000000000000227
164.0
View
TLS2_k127_4892905_5
-
-
-
-
0.000000000000000000000000000000000003714
143.0
View
TLS2_k127_4892905_6
Adenylate cyclase
-
-
-
0.0000000000000000000001035
103.0
View
TLS2_k127_489474_0
Putative S-adenosyl-L-methionine-dependent methyltransferase
K00574,K18164
-
2.1.1.79
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487
354.0
View
TLS2_k127_489474_1
Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K13292
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097
330.0
View
TLS2_k127_489474_2
Belongs to the multicopper oxidase YfiH RL5 family
K05810
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004732
291.0
View
TLS2_k127_489474_3
-
-
-
-
0.00000000000000000000000000000000000000000000000000000001647
212.0
View
TLS2_k127_489474_4
Membrane fusogenic activity
K09806
-
-
0.00000000000000000000001219
115.0
View
TLS2_k127_489474_5
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K00948
-
2.7.6.1
0.00000000000000000000001672
101.0
View
TLS2_k127_4904415_0
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
K00254
-
1.3.5.2
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387
407.0
View
TLS2_k127_4904415_1
Peptidase S24-like
-
-
-
0.000000000000000000000000000000000000000738
162.0
View
TLS2_k127_4904415_2
arsenate reductase
K00537
-
1.20.4.1
0.000000000000000000000000000000000000001004
161.0
View
TLS2_k127_4904415_3
Protein of unknown function (DUF952)
-
-
-
0.0000000000000000000000000000000006979
133.0
View
TLS2_k127_4904415_4
repressor
-
-
-
0.000000000000000000000000000003482
128.0
View
TLS2_k127_4904415_5
-
-
-
-
0.0000000000000000000001276
100.0
View
TLS2_k127_4904415_6
nuclease
-
-
-
0.0000000324
64.0
View
TLS2_k127_4906006_0
ErfK YbiS YcfS YnhG family protein
K21470,K21572
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455
350.0
View
TLS2_k127_4906006_1
pfam nudix
-
-
-
0.0000000000000000000000000000000000000000000000000000000004471
206.0
View
TLS2_k127_4906006_2
Dolichyl-phosphate-mannose-protein mannosyltransferase
-
-
-
0.000000000000000000000000000000000000000000000000005263
188.0
View
TLS2_k127_4906006_3
COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
-
-
-
0.000000000000000000000000000000000000000000000000008562
192.0
View
TLS2_k127_4906006_4
Cell Wall
-
-
-
0.00000000000000000000000000000000000000000005073
169.0
View
TLS2_k127_4906006_5
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
K01595
-
4.1.1.31
0.0000000000004592
72.0
View
TLS2_k127_4912611_0
Carbon-nitrogen hydrolase
K11206
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331
337.0
View
TLS2_k127_4912611_1
Belongs to the aspartokinase family
K00928
GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
2.7.2.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001607
293.0
View
TLS2_k127_4912611_2
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway
K00568
-
2.1.1.222,2.1.1.64
0.000000000000000000000000000000000000000000000000000000000000000000000000000000002631
288.0
View
TLS2_k127_4912611_3
L,D-transpeptidase catalytic domain
-
-
-
0.000000000000000000000000000000000006323
149.0
View
TLS2_k127_4912611_4
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K03676
-
-
0.00000000000000000000000000004068
119.0
View
TLS2_k127_4913250_0
Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
K00833
-
2.6.1.62
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114
476.0
View
TLS2_k127_4913250_1
Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
K01935,K02169
-
2.1.1.197,6.3.3.3
0.000000000000000000000000000000000000000000000000000000000111
211.0
View
TLS2_k127_4913250_2
Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
K01935,K02169
-
2.1.1.197,6.3.3.3
0.0000000000000000000000000000000000000000004563
167.0
View
TLS2_k127_4913250_3
carboxylic ester hydrolase activity
K02170
-
3.1.1.85
0.0000000000000000000000000000000006213
138.0
View
TLS2_k127_4913250_4
Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
K00652
-
2.3.1.47
0.0000000000000000000000003741
108.0
View
TLS2_k127_4957432_0
Protein of unknown function (DUF3365)
K01768
-
4.6.1.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331
363.0
View
TLS2_k127_4957432_1
GAF domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000000005266
246.0
View
TLS2_k127_4957432_2
Stage II sporulation protein E (SpoIIE)
-
-
-
0.000000000000000000000000000000000000000000000000000000003478
228.0
View
TLS2_k127_4957432_3
-
-
-
-
0.000000000000000000000000000000000000000000000001441
179.0
View
TLS2_k127_4957432_4
Domain of unknown function (DUF1987)
-
-
-
0.000000000000000000000000000000001319
137.0
View
TLS2_k127_4958911_0
hydrolase of the metallo-beta-lactamase superfamily
K12574
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000001566
276.0
View
TLS2_k127_4958911_1
Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
K05606
-
5.1.99.1
0.0000000000000000000000000000000000000000000000000000000000000000005146
229.0
View
TLS2_k127_4958911_2
Protein of unknown function (DUF1467)
-
-
-
0.00000000000000001143
85.0
View
TLS2_k127_4959659_0
NADH-ubiquinone oxidoreductase chain 49kDa
-
-
-
1.454e-205
649.0
View
TLS2_k127_4959659_1
Proton-conducting membrane transporter
K12141
-
-
8.482e-198
624.0
View
TLS2_k127_4969847_0
ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
K06942
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155
579.0
View
TLS2_k127_4969847_1
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K00948
-
2.7.6.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322
483.0
View
TLS2_k127_4969847_2
Haem-degrading
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000001111
250.0
View
TLS2_k127_4969847_3
The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
K01056
GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101
3.1.1.29
0.000000000000000000000000000000000000000000000000000000000000000000000358
246.0
View
TLS2_k127_4969847_4
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K02897
GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.0000000000000000000000000000000000000000000000000000000000000000000005894
243.0
View
TLS2_k127_4969847_5
Protein of unknown function (DUF502)
-
-
-
0.000000000000000000000000000000000000000000000000000000000005926
216.0
View
TLS2_k127_4969847_6
methyl-accepting chemotaxis protein
K03406
-
-
0.000000000000000000000000000000000000000000000001193
180.0
View
TLS2_k127_4969847_7
Dodecin
K09165
-
-
0.000000000000000000003162
95.0
View
TLS2_k127_4976194_0
NADH-ubiquinone oxidoreductase subunit G, C-terminal
K00336
-
1.6.5.3
7.113e-315
981.0
View
TLS2_k127_4976194_1
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K00337
GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114
1.6.5.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245
518.0
View
TLS2_k127_4976194_2
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K00335
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
1.6.5.3
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473
468.0
View
TLS2_k127_4976194_3
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K00338,K03941
GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114
1.6.5.3,1.6.99.3
0.000000000000000000000000001096
113.0
View
TLS2_k127_4976194_4
-
-
-
-
0.000007889
54.0
View
TLS2_k127_4977811_0
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
K00962
GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575
2.7.7.8
0.0
1050.0
View
TLS2_k127_4977811_1
Belongs to the beta-ketoacyl-ACP synthases family
K00647
GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576
2.3.1.41
2.891e-207
649.0
View
TLS2_k127_4977811_10
Bacterial-like globin
K06886
-
-
0.00000000000000000000000000001285
122.0
View
TLS2_k127_4977811_11
Bacterial SH3 domain homologues
K01876
-
6.1.1.12
0.00000000000000000000000000002312
119.0
View
TLS2_k127_4977811_12
-
-
-
-
0.00006493
48.0
View
TLS2_k127_4977811_2
Enoyl- acyl-carrier-protein reductase NADH
K00208
GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576
1.3.1.10,1.3.1.9
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486
429.0
View
TLS2_k127_4977811_3
Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K03177
GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481
5.4.99.25
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225
371.0
View
TLS2_k127_4977811_4
Translation-initiation factor 2
K02519
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147
348.0
View
TLS2_k127_4977811_5
Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length
K01716
-
4.2.1.59,5.3.3.14
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459
309.0
View
TLS2_k127_4977811_6
COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000005727
258.0
View
TLS2_k127_4977811_7
Belongs to the Fur family
K09826
-
-
0.0000000000000000000000000000000000000000000000003996
181.0
View
TLS2_k127_4977811_8
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K02834
-
-
0.000000000000000000000000000000000000000002381
158.0
View
TLS2_k127_4977811_9
Ribosomal_S15
K02956
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904
-
0.000000000000000000000000000000000000001946
149.0
View
TLS2_k127_4986409_0
Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
K04077
GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220
-
9.84e-275
853.0
View
TLS2_k127_4986409_1
Protein of unknown function DUF72
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000006006
268.0
View
TLS2_k127_4986409_2
PFAM GYD family protein
-
-
-
0.000000000000000000000000008755
113.0
View
TLS2_k127_4991262_0
MoeA N-terminal region (domain I and II)
K03750
GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657
2.10.1.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925
400.0
View
TLS2_k127_4991262_1
Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
K03637
-
4.6.1.17
0.000000000000000000000000000000006326
128.0
View
TLS2_k127_4991262_2
LexA DNA binding domain
K01356
GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141
3.4.21.88
0.0000000008812
59.0
View
TLS2_k127_49972_0
membrane transporter protein
K07090
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000004816
251.0
View
TLS2_k127_49972_1
Putative transmembrane protein (Alph_Pro_TM)
-
-
-
0.000000000000000000000000000000000000000000000000002336
198.0
View
TLS2_k127_49972_2
Calcineurin-like phosphoesterase
K06953
-
-
0.00000000000000000000000000000000000000000000001071
175.0
View
TLS2_k127_5019013_0
Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K03307
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399
595.0
View
TLS2_k127_5022500_0
Sulfatase-modifying factor enzyme 1
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000005366
269.0
View
TLS2_k127_5022500_1
transcriptional regulator
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000001405
256.0
View
TLS2_k127_5022500_2
-
-
-
-
0.000000000000000000000000000000000000000000000004156
176.0
View
TLS2_k127_5022500_3
Sulfatase-modifying factor enzyme 1
-
-
-
0.000000000804
61.0
View
TLS2_k127_5028384_0
Formate dehydrogenase subunit alpha
-
-
-
0.0
1109.0
View
TLS2_k127_5028384_1
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K00122
-
1.17.1.9
1.163e-232
737.0
View
TLS2_k127_5028384_2
COG4662 ABC-type tungstate transport system, periplasmic component
K05773
-
-
0.0000000000000000000000000002801
123.0
View
TLS2_k127_5050573_0
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K01756
GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
4.3.2.2
2.298e-221
692.0
View
TLS2_k127_5050573_1
COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
K01999
-
-
0.000000000000000000000000000000000000000000000000000000000000000000001342
239.0
View
TLS2_k127_5050573_2
Belongs to the HpcH HpaI aldolase family
K02510
-
4.1.2.52
0.0000000000000000000000000000000000000000000000008114
187.0
View
TLS2_k127_5050573_3
Domain of unknown function (DUF1476)
-
-
-
0.0000000000000000000000000000000000001032
143.0
View
TLS2_k127_5050573_4
-
-
-
-
0.00000000000001774
87.0
View
TLS2_k127_5052444_0
Lipoprotein releasing system transmembrane protein
K09808
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187
545.0
View
TLS2_k127_5052444_1
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner
K09810
GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000016
295.0
View
TLS2_k127_5052444_2
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
K01881
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
6.1.1.15
0.0000000000000000000000000000000000000000000000000000002789
196.0
View
TLS2_k127_5052444_3
DNA polymerase
K02337
GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496
2.7.7.7
0.000000000000000000000000000000000000000000000000000002123
197.0
View
TLS2_k127_5064273_0
Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S
K00311
-
1.5.5.1
4.688e-264
824.0
View
TLS2_k127_5064273_1
May be involved in the biosynthesis of molybdopterin
K03638
GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464
2.7.7.75
0.00000000000000000000000000000000000000000000000000000000000000000000000000000004412
271.0
View
TLS2_k127_5064273_2
Uracil DNA glycosylase superfamily
K21929
-
3.2.2.27
0.000000000000000000000000000000000000000000000000000000000000000000000000006408
265.0
View
TLS2_k127_5064273_3
Diguanylate cyclase, GGDEF domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000593
239.0
View
TLS2_k127_5064273_4
Zinc-dependent metalloprotease
-
-
-
0.00001349
57.0
View
TLS2_k127_5069296_0
Cell division protein
K09811
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306
344.0
View
TLS2_k127_5069296_1
cell division ATP-binding protein FtsE
K09812
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412
310.0
View
TLS2_k127_5069296_2
Phosphate acyltransferases
K00655
-
2.3.1.51
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818
314.0
View
TLS2_k127_5069296_3
DUF218 domain
-
-
-
0.0000000000000000000000000000000000000000000000001012
184.0
View
TLS2_k127_508313_0
Erythromycin esterase
K00573
-
2.1.1.77
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928
484.0
View
TLS2_k127_508313_1
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K02005,K13888
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515
360.0
View
TLS2_k127_508313_2
COG1136 ABC-type antimicrobial peptide transport system ATPase component
K02003
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000003931
287.0
View
TLS2_k127_5109919_0
DinB superfamily
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284
574.0
View
TLS2_k127_5109919_1
Histidine-specific methyltransferase, SAM-dependent
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586
336.0
View
TLS2_k127_5109919_2
Phosphodiester glycosidase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000001588
266.0
View
TLS2_k127_5125628_0
Peptidase family M50
K11749
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086
471.0
View
TLS2_k127_5125628_1
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
K00099
GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576
1.1.1.267
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249
441.0
View
TLS2_k127_5125628_2
Cytidylyltransferase family
K00981
-
2.7.7.41
0.0000000000000000000000000000000000000000000000000000008787
203.0
View
TLS2_k127_5125628_3
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K00806
GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617
2.5.1.31
0.00000000000000000000000000001094
119.0
View
TLS2_k127_512714_0
that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K03555
GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206
508.0
View
TLS2_k127_512714_1
Involved in the biosynthesis of porphyrin-containing compound
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009678
471.0
View
TLS2_k127_512714_2
Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K00989
GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575
2.7.7.56
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309
375.0
View
TLS2_k127_512714_3
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K02428
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576
3.6.1.66
0.00000000000000000000000000000000000000000000000000000000000000000006671
241.0
View
TLS2_k127_512714_4
Penicillin binding protein transpeptidase domain
K17838,K19211,K21277
-
3.5.2.6
0.000000000000000000000000000000000000000000000000000000000000000001445
238.0
View
TLS2_k127_512714_5
LppC putative lipoprotein
-
-
-
0.00000000000000000000000000000000000000000000000002128
183.0
View
TLS2_k127_5148307_0
-
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111
355.0
View
TLS2_k127_5148307_1
PFAM type I phosphodiesterase nucleotide pyrophosphatase
-
-
-
0.00000000000000000000000005355
109.0
View
TLS2_k127_5180072_0
Zn-dependent metallo-hydrolase RNA specificity domain
K12574
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125
462.0
View
TLS2_k127_5180072_1
Biotin protein ligase C terminal domain
K03524
-
6.3.4.15
0.0000000000000000000000000000000000000000001431
166.0
View
TLS2_k127_5180383_0
Glycosyl hydrolases family 15
-
-
-
9.327e-242
759.0
View
TLS2_k127_5180383_1
Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K02379
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149
336.0
View
TLS2_k127_5180383_2
Removes the phosphate from trehalose 6-phosphate to produce free trehalose
K01087
-
3.1.3.12
0.00000000000000000000000000000000000000000000000000000000000000000008325
239.0
View
TLS2_k127_5180383_3
(twin-arginine translocation) pathway signal
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000008106
225.0
View
TLS2_k127_5180383_4
von Willebrand factor, type A
-
-
-
0.0000000000000000000000000000000000000000000000000000005998
201.0
View
TLS2_k127_5180383_5
Rhomboid family
-
-
-
0.000000000000000001351
86.0
View
TLS2_k127_5233184_0
Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide
K01739,K10764
GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
2.5.1.48
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229
551.0
View
TLS2_k127_5233184_1
2'-deoxycytidine 5'-triphosphate deaminase (DCD)
K01494
-
3.5.4.13
0.0000000000000000000000000000255
122.0
View
TLS2_k127_5233184_2
Uncharacterized conserved protein (DUF2277)
-
-
-
0.000000000000000000008616
96.0
View
TLS2_k127_5286841_0
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
K01596
-
4.1.1.32
1.5e-323
995.0
View
TLS2_k127_5286841_1
Gamma-glutamyltranspeptidase
K00681
-
2.3.2.2,3.4.19.13
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065
419.0
View
TLS2_k127_5377756_0
-
-
-
-
0.00000000000000000000000000000000000002287
154.0
View
TLS2_k127_5377756_1
Sugar-transfer associated ATP-grasp
-
-
-
0.00000000000000000000000000009614
124.0
View
TLS2_k127_5377756_2
integral membrane protein
-
-
-
0.00001851
55.0
View
TLS2_k127_5411820_0
SurA N-terminal domain
K01802,K03770
-
5.2.1.8
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577
310.0
View
TLS2_k127_5411820_1
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K01657,K13503
-
4.1.3.27
0.0000000000000000000000008198
112.0
View
TLS2_k127_5421523_0
Rod shape-determining protein (MreB)
K03569
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537
376.0
View
TLS2_k127_5421523_1
shape-determining protein MreC
K03570
-
-
0.0000000000000000000000000000000000000000000000000000002346
209.0
View
TLS2_k127_544181_0
Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
K00382
GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204
1.8.1.4
4.114e-222
696.0
View
TLS2_k127_544181_1
-
-
-
-
0.000000000000000000000000000343
119.0
View
TLS2_k127_544181_2
-
-
-
-
0.0000003187
61.0
View
TLS2_k127_5502834_0
Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family
K03185
GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941
407.0
View
TLS2_k127_5502834_1
tRNA synthetases class I (E and Q), catalytic domain
K01894
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144
367.0
View
TLS2_k127_5502834_2
peptidase S16
K01338,K07157
-
3.4.21.53
0.000000000000000000000000000000000000000000000000000000000000000000000002775
249.0
View
TLS2_k127_5502834_3
Trm112p-like protein
K09791
-
-
0.00000000000000000000002309
104.0
View
TLS2_k127_5613876_0
HAMP domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003
436.0
View
TLS2_k127_5613876_1
Transcriptional regulatory protein, C terminal
K02483,K07659
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147
351.0
View
TLS2_k127_5613876_2
ubiE/COQ5 methyltransferase family
K07755
-
2.1.1.137
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561
318.0
View
TLS2_k127_5613876_3
polygalacturonase activity
-
-
-
0.000000000000000000000000000000000000000000000000000000000003345
221.0
View
TLS2_k127_5613876_4
Belongs to the sigma-70 factor family. ECF subfamily
K03088
-
-
0.00000000000000000000000000000000000006802
151.0
View
TLS2_k127_5613876_5
Catabolite gene activator and regulatory subunit of cAMP-dependent protein
-
-
-
0.000000000000000000000000000000000804
137.0
View
TLS2_k127_5613876_6
Evidence 4 Homologs of previously reported genes of
-
-
-
0.0000000000000000000187
101.0
View
TLS2_k127_5613876_7
-
-
-
-
0.0000000000005062
70.0
View
TLS2_k127_5614226_0
Heat shock 70 kDa protein
K04043
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019
517.0
View
TLS2_k127_5614226_1
Alkylated DNA repair protein
K03919
-
1.14.11.33
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495
293.0
View
TLS2_k127_5614226_2
PFAM Methyltransferase type 11
-
-
-
0.000000000000000000000000000000000000000001505
167.0
View
TLS2_k127_5617107_0
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K00858
-
2.7.1.23
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529
367.0
View
TLS2_k127_5617107_1
Nitroreductase family
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000339
232.0
View
TLS2_k127_5617107_2
CutA1 divalent ion tolerance protein
K03926
-
-
0.000000000000000000000000000001551
135.0
View
TLS2_k127_5621810_0
PFAM aldo keto reductase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969
426.0
View
TLS2_k127_5621810_1
ABC-type branched-chain amino acid transport systems, periplasmic component
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000003112
250.0
View
TLS2_k127_5621810_2
Carboxylesterase family
K01066
-
-
0.00000000000000000000000000000000000000000000000000000000000000001056
239.0
View
TLS2_k127_5621810_3
-
-
-
-
0.000000000000000000000000000000000000000000000000000000000000009072
224.0
View
TLS2_k127_5621810_4
-
-
-
-
0.0000000000000000000000000000000000000000000000000000000000001624
219.0
View
TLS2_k127_5621810_5
-
-
-
-
0.0000000000000000000193
93.0
View
TLS2_k127_5621810_6
receptor
K02014
-
-
0.0002488
47.0
View
TLS2_k127_5623331_0
Catalyzes the ferrous insertion into protoporphyrin IX
K01772
GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
4.99.1.1,4.99.1.9
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605
477.0
View
TLS2_k127_5623331_1
prohibitin homologues
-
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598
428.0
View
TLS2_k127_5623331_2
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K00111
-
1.1.5.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332
344.0
View
TLS2_k127_5623331_3
Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000003823
273.0
View
TLS2_k127_5623331_4
NfeD-like C-terminal, partner-binding
K07340
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
-
0.0000000000000000000000000000000000342
139.0
View
TLS2_k127_5623331_5
-
-
-
-
0.000000000001781
79.0
View
TLS2_k127_5625201_0
PFAM Carbohydrate-selective porin OprB
K07267
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351
348.0
View
TLS2_k127_5625201_1
Imelysin
K07231
-
-
0.0000000000000000000000000000000000000000000000000000002838
197.0
View
TLS2_k127_5625201_2
Imelysin
K07231
-
-
0.00000000136
59.0
View
TLS2_k127_5628247_0
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K00335
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
1.6.5.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923
373.0
View
TLS2_k127_5628247_1
Thioredoxin-like [2Fe-2S] ferredoxin
K00334,K03943
-
1.6.5.3,1.6.99.3
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315
307.0
View
TLS2_k127_5628247_2
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K00333
GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114
1.6.5.3
0.0000000000000002149
78.0
View
TLS2_k127_5642015_0
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K03527
-
1.17.7.4
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171
476.0
View
TLS2_k127_5642015_1
Belongs to the pseudomonas-type ThrB family
K02204
-
2.7.1.39
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152
447.0
View
TLS2_k127_5642015_2
RNase H
K03469
-
3.1.26.4
0.00000000000000000000000000000000000000000000000000000000000000000000006131
242.0
View
TLS2_k127_5642015_3
Redoxin
K03386
-
1.11.1.15
0.00000000000000000000001549
100.0
View
TLS2_k127_5646666_0
PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein
K01738,K01740
GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
2.5.1.47,2.5.1.49
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383
340.0
View
TLS2_k127_5646666_1
enoyl-CoA hydratase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211
329.0
View
TLS2_k127_5646666_2
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K02871
GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.0000000000000000000000000000000000000000000000000000000000000000000006545
241.0
View
TLS2_k127_5646666_3
Belongs to the universal ribosomal protein uS9 family
K02996
GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.0000000000000000000000000000000000000000000000000000000000000000001578
232.0
View
TLS2_k127_5646666_4
CoA binding domain
K06929
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464
-
0.000000000000000000000000000000000000000000000000000000000000002618
224.0
View
TLS2_k127_5646666_5
Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K00145
-
1.2.1.38
0.000000000000000000000000003475
116.0
View
TLS2_k127_5660327_0
membrane
-
-
-
4.795e-244
771.0
View
TLS2_k127_5660327_1
Domain of unknown function (DUF4159)
-
-
-
7.491e-238
755.0
View
TLS2_k127_5666014_0
LysR substrate binding domain
K04761
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097
327.0
View
TLS2_k127_5666014_1
Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K14393
-
-
0.000000000000000000000000000000000000000000000000000000000000009845
235.0
View
TLS2_k127_5674699_0
Belongs to the binding-protein-dependent transport system permease family
K01997
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893
478.0
View
TLS2_k127_5674699_1
Transcriptional
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269
300.0
View
TLS2_k127_5685296_0
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase
K02337,K14162
GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496
2.7.7.7
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683
419.0
View
TLS2_k127_5685296_1
Nucleotidyltransferase DNA polymerase involved in DNA repair
K14161
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135
377.0
View
TLS2_k127_5685296_2
SOS response
K14160
-
-
0.0000000000000001078
91.0
View
TLS2_k127_5685296_3
Flp Fap pilin component
K02651
-
-
0.0000000000000005877
80.0
View
TLS2_k127_5704091_0
Respiratory-chain NADH dehydrogenase, 49 Kd subunit
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185
563.0
View
TLS2_k127_5704091_1
CHASE3 domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139
308.0
View
TLS2_k127_5704091_2
NADH ubiquinone oxidoreductase, 20 Kd subunit
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000002066
271.0
View
TLS2_k127_5704091_3
cheY-homologous receiver domain
-
-
-
0.000000000000000000000000000000008655
131.0
View
TLS2_k127_5721000_0
Major facilitator superfamily
-
-
-
3.272e-267
833.0
View
TLS2_k127_5721000_1
Catalyzes the NAD( )-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non- methylotrophic organisms
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414
355.0
View
TLS2_k127_5721000_2
Cation efflux family
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000002976
264.0
View
TLS2_k127_5731316_0
Adenylyl- / guanylyl cyclase, catalytic domain
K01768
-
4.6.1.1
1.881e-211
680.0
View
TLS2_k127_5731316_1
Sulfate transporter
K03321
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158
308.0
View
TLS2_k127_5731316_2
Protein of unknown function (DUF3307)
-
-
-
0.0000000000000000000000000000000003951
138.0
View
TLS2_k127_5739775_0
ErfK YbiS YcfS YnhG family protein
K21470
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372
417.0
View
TLS2_k127_5739775_1
-
-
-
-
0.000000000000000000000000000000000000000001394
165.0
View
TLS2_k127_5739775_2
molecular chaperone
-
-
-
0.00000000000000000000001239
111.0
View
TLS2_k127_5743767_0
PFAM Amylo-alpha-16-glucosidase
-
-
-
9.443e-204
659.0
View
TLS2_k127_5743767_1
Glycosyl transferases group 1
K12995
-
2.4.1.348
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359
432.0
View
TLS2_k127_5743767_2
Beta-lactamase
-
-
-
0.000000000000000000000000000000007266
132.0
View
TLS2_k127_5743767_3
Beta-lactamase
-
-
-
0.000000000000000000666
87.0
View
TLS2_k127_5746369_0
Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K00240
-
1.3.5.1,1.3.5.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241
311.0
View
TLS2_k127_5746369_1
Glyoxalase bleomycin resistance protein dioxygenase
-
-
-
0.00000000000000000000000000000000000000000000000003556
183.0
View
TLS2_k127_5751706_0
cobalt chelatase
K09883
-
6.6.1.2
7.348e-233
743.0
View
TLS2_k127_5751706_1
Cobaltochelatase CobS subunit N terminal
K09882
-
6.6.1.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858
312.0
View
TLS2_k127_5755644_0
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
K00384
-
1.8.1.9
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557
454.0
View
TLS2_k127_5755644_1
-
-
-
-
0.000000000000000000000000000000000000001892
155.0
View
TLS2_k127_5755644_2
Phasin protein
-
-
-
0.0000000000000000000000000000001179
130.0
View
TLS2_k127_5755644_3
helix_turn_helix ASNC type
-
GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141
-
0.0000000000000000000123
94.0
View
TLS2_k127_5755965_0
ATPase AAA
K03924
GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226
503.0
View
TLS2_k127_5755965_1
Protein of unknown function (DUF1285)
K09986
-
-
0.00000000000000000000000000000000000000000000003627
177.0
View
TLS2_k127_5755965_2
Protein of unknown function DUF58
-
-
-
0.000000000000000000000000006229
114.0
View
TLS2_k127_5766073_0
Belongs to the GPI family
K01810,K13810
-
2.2.1.2,5.3.1.9
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842
534.0
View
TLS2_k127_5766073_1
Belongs to the peptidase M16 family
K07263
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283
530.0
View
TLS2_k127_5766073_2
Peptidase M16 inactive domain
K07263,K07623
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338
472.0
View
TLS2_k127_5766073_3
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K03572
GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864
400.0
View
TLS2_k127_5766602_0
Putative diguanylate phosphodiesterase
K13245
-
3.1.4.52
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135
516.0
View
TLS2_k127_5766602_1
Belongs to the UPF0301 (AlgH) family
K07735
-
-
0.00000000000000000000000000000001054
127.0
View
TLS2_k127_5773767_0
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868
602.0
View
TLS2_k127_5773767_1
EF hand
-
-
-
0.0000000000000001667
91.0
View
TLS2_k127_5773767_2
Ceramidase
-
-
-
0.0000007305
54.0
View
TLS2_k127_5795732_0
Alpha beta hydrolase
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978
312.0
View
TLS2_k127_5795732_1
ribonuclease BN
K07058
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455
309.0
View
TLS2_k127_5795732_2
PFAM Lytic transglycosylase catalytic
K08309
-
-
0.0000000000000000000000000000000000000000000000000000000000003082
219.0
View
TLS2_k127_5795732_3
Belongs to the ompA family
K03286
-
-
0.00000000000000000000000000000000003495
149.0
View
TLS2_k127_5795732_4
Protein of unknown function (DUF3096)
-
-
-
0.000000005254
61.0
View
TLS2_k127_5800617_0
alanine symporter
K03310
-
-
2.949e-206
649.0
View
TLS2_k127_5800617_1
2'-deoxycytidine 5'-triphosphate deaminase (DCD)
K01494
-
3.5.4.13
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752
358.0
View
TLS2_k127_5800617_2
4Fe-4S single cluster domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989
331.0
View
TLS2_k127_5800617_3
Sulfotransferase domain
-
-
-
0.000000000000000000000000000000000000000000003446
171.0
View
TLS2_k127_5800617_5
Sulfotransferase domain
-
-
-
0.00000000000000000000001158
102.0
View
TLS2_k127_5801602_0
CYTH
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182
329.0
View
TLS2_k127_5801602_1
CBS domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000004723
237.0
View
TLS2_k127_5801602_2
Amidase
K01457
-
3.5.1.54
0.0000000000000000000000000000000000000000000000000000003086
196.0
View
TLS2_k127_5801602_3
Domain in cystathionine beta-synthase and other proteins.
-
-
-
0.0000000000000000000000000000000000000000000005419
169.0
View
TLS2_k127_5801602_4
PFAM Cold-shock protein, DNA-binding
-
-
-
0.0000000000000000000000000000000000000000004439
162.0
View
TLS2_k127_5801602_5
sporulation resulting in formation of a cellular spore
K01449
-
3.5.1.28
0.000000000000000000000000000000009275
136.0
View
TLS2_k127_5801602_6
GGDEF domain
-
-
-
0.00000000000000000000000000000004526
142.0
View
TLS2_k127_5801602_7
diguanylate cyclase
-
-
-
0.000004835
58.0
View
TLS2_k127_5801602_8
Bacterial protein of unknown function (DUF883)
-
-
-
0.000006504
51.0
View
TLS2_k127_5817425_0
poly(R)-hydroxyalkanoic acid synthase
K03821
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
-
5.584e-264
826.0
View
TLS2_k127_5817425_1
Aminotransferase
K14261
GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222
608.0
View
TLS2_k127_5817425_2
Putative zinc-binding metallo-peptidase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372
332.0
View
TLS2_k127_5821810_0
FAD linked oxidases, C-terminal domain
K00102
GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617
1.1.2.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391
526.0
View
TLS2_k127_5821810_1
PFAM Histone deacetylase domain
K04768
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492
404.0
View
TLS2_k127_5821810_2
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
K07566
GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363
2.7.7.87
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277
353.0
View
TLS2_k127_5821810_3
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
K03602
-
3.1.11.6
0.0000102
49.0
View
TLS2_k127_5833216_0
Transposase
-
-
-
9.081e-224
700.0
View
TLS2_k127_5843384_0
GTPase that plays an essential role in the late steps of ribosome biogenesis
K03977
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454
548.0
View
TLS2_k127_5843384_1
helix_turn_helix, arabinose operon control protein
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197
495.0
View
TLS2_k127_5843384_2
PQQ-like domain
K17713
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825
447.0
View
TLS2_k127_5843384_3
PFAM Adenosine AMP deaminase
K01488
-
3.5.4.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647
312.0
View
TLS2_k127_5843384_4
OsmC-like protein
-
-
-
0.000000000000000000000000000000000000000000000000000000000003839
213.0
View
TLS2_k127_5843384_5
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
K00940
-
2.7.4.6
0.0000000000000000000000000000000000000000000000000000000005907
205.0
View
TLS2_k127_5843384_6
DNA polymerase III chi subunit, HolC
K02339
-
2.7.7.7
0.00000000000000000000000000000000000000000000000008797
193.0
View
TLS2_k127_5843384_7
Tetratricopeptide repeat-like domain
-
-
-
0.0000001604
54.0
View
TLS2_k127_584561_0
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K01657
-
4.1.3.27
1.064e-204
646.0
View
TLS2_k127_584561_1
Peptidase C26
K01658,K01664
-
2.6.1.85,4.1.3.27
0.00000000000000000000000000000000000000000000001102
172.0
View
TLS2_k127_584561_2
phosphohistidine phosphatase, SixA
K08296
-
-
0.0000000000000000000000000000000000000004635
156.0
View
TLS2_k127_5847637_0
Belongs to the peptidase S1C family
K04771
-
3.4.21.107
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592
514.0
View
TLS2_k127_5847637_1
His Kinase A (phosphoacceptor) domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179
454.0
View
TLS2_k127_5847637_2
Transcriptional regulator
K02483
GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623
371.0
View
TLS2_k127_5847637_3
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
K00982
GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090
2.7.7.42,2.7.7.89
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603
378.0
View
TLS2_k127_5847637_4
Cytochrome c-type biogenesis protein
K02198
-
-
0.0000000000000000000000000000000000000000000000000000000004935
205.0
View
TLS2_k127_5847637_5
subunit of a heme lyase
K02200
-
-
0.000000000000000000000000000000000000000000004127
174.0
View
TLS2_k127_5850484_0
E1 component
K00164
-
1.2.4.2
1.685e-301
931.0
View
TLS2_k127_5850484_1
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
K00658
-
2.3.1.61
0.000000000000000000003735
93.0
View
TLS2_k127_5858820_0
Catalyzes the oxidation of L-aspartate to iminoaspartate
K00278
-
1.4.3.16
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604
569.0
View
TLS2_k127_5858820_1
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K03517
-
2.5.1.72
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481
528.0
View
TLS2_k127_5858820_2
Quinolinate phosphoribosyl transferase, C-terminal domain
K00767,K03813
-
2.4.2.19
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269
323.0
View
TLS2_k127_5858820_3
ErfK YbiS YcfS YnhG family protein
K21470
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516
325.0
View
TLS2_k127_5858820_4
Cell wall hydrolyses involved in spore germination
-
-
-
0.0000000000000001028
84.0
View
TLS2_k127_5858820_5
-
-
-
-
0.000000007847
58.0
View
TLS2_k127_5868858_0
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
K00609
GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
2.1.3.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671
488.0
View
TLS2_k127_5868858_1
Beta-lactamase superfamily domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000007545
271.0
View
TLS2_k127_5868858_2
Disulfide bond formation protein DsbB
-
-
-
0.0000000000000000000000000000000000000000000000000000000029
205.0
View
TLS2_k127_5868858_3
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K07447
GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360
-
0.0000000000000000000000000000000000000000000000000000002475
198.0
View
TLS2_k127_5875899_0
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K00764
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464
2.4.2.14
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574
567.0
View
TLS2_k127_5875899_1
Beta-lactamase superfamily domain
K06167
-
3.1.4.55
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126
362.0
View
TLS2_k127_5875899_2
Hydrolase, TatD family
K03424
GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619
329.0
View
TLS2_k127_5875899_3
KR domain
-
GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000001557
271.0
View
TLS2_k127_5875899_4
Outer membrane autotransporter
-
-
-
0.0000005435
59.0
View
TLS2_k127_5900927_0
ErfK YbiS YcfS YnhG family protein
K21470
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792
415.0
View
TLS2_k127_5900927_1
Bacterial protein of unknown function (DUF882)
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000004921
273.0
View
TLS2_k127_5900927_2
Sigma-54 interaction domain
-
GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141
-
0.000000000000000000000000000000000000000000000000000000000000000000008154
237.0
View
TLS2_k127_5900927_3
MgtC family
K07507
-
-
0.0000000000000000000000000000000000000000000000773
173.0
View
TLS2_k127_5900927_4
Protein conserved in bacteria
K09948
-
-
0.00000000000000000000000000000000006014
140.0
View
TLS2_k127_5900927_5
Belongs to the UPF0335 family
-
-
-
0.0000000000000000000000001871
109.0
View
TLS2_k127_5911133_1
AntiSigma factor
-
-
-
0.0000000000000000007127
98.0
View
TLS2_k127_5911133_2
Belongs to the sigma-70 factor family. ECF subfamily
K03088
-
-
0.0000000000001515
78.0
View
TLS2_k127_5911133_3
protein containing double-stranded beta helix domain
-
-
-
0.00000002506
61.0
View
TLS2_k127_5916676_0
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
K10563
-
3.2.2.23,4.2.99.18
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704
357.0
View
TLS2_k127_5916676_1
Belongs to the enoyl-CoA hydratase isomerase family
K01692
-
4.2.1.17
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811
360.0
View
TLS2_k127_5916676_2
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)
K03183
-
2.1.1.163,2.1.1.201
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499
324.0
View
TLS2_k127_5927867_0
GntP family permease
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387
553.0
View
TLS2_k127_5927867_1
Glutaminase
K01425
-
3.5.1.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224
440.0
View
TLS2_k127_5927867_10
-
-
-
-
0.0000002501
62.0
View
TLS2_k127_5927867_2
glutamine synthetase
K01915
-
6.3.1.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955
402.0
View
TLS2_k127_5927867_3
Alpha beta hydrolase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108
318.0
View
TLS2_k127_5927867_4
esterase of the alpha-beta hydrolase superfamily
K07001
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002977
291.0
View
TLS2_k127_5927867_5
PFAM Metallophosphoesterase
K07096
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000003126
273.0
View
TLS2_k127_5927867_6
Patatin-like phospholipase
K07001
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000008376
252.0
View
TLS2_k127_5927867_7
amino acid
-
-
-
0.0000000000000000000000000000000000000000000000000006344
206.0
View
TLS2_k127_5927867_8
-
-
-
-
0.00000000000000000000000000000000000000000002175
172.0
View
TLS2_k127_5927867_9
PFAM regulatory protein, MerR
-
-
-
0.000000002587
68.0
View
TLS2_k127_5955433_0
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
K13598
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
2.7.13.3
7.732e-232
741.0
View
TLS2_k127_5955433_1
Sigma-54 interaction domain
K13599
-
-
0.000000000000000000000000000000000000000000000000000003432
191.0
View
TLS2_k127_5960926_0
Transposase DDE domain
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639
493.0
View
TLS2_k127_6009728_0
AsmA-like C-terminal region
K07289
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000002509
290.0
View
TLS2_k127_6009728_1
Sodium:sulfate symporter transmembrane region
-
-
-
0.00000000000000000000000000000003394
126.0
View
TLS2_k127_6009728_2
-
-
-
-
0.0001663
49.0
View
TLS2_k127_603296_0
Belongs to the GcvT family
K19191
GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606
1.5.3.19
0.0
1415.0
View
TLS2_k127_603296_1
Phytanoyl-CoA dioxygenase (PhyH)
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605
409.0
View
TLS2_k127_603296_2
Choline kinase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044
351.0
View
TLS2_k127_603296_3
integral membrane protein
-
-
-
0.000000000000000000000000000000000000000000000000000005808
196.0
View
TLS2_k127_603296_4
Alpha/beta hydrolase family
K06889
-
-
0.0000000000000000000000000000000000000000000000001587
190.0
View
TLS2_k127_60697_0
COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202
565.0
View
TLS2_k127_60697_1
transport system, fused permease components
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132
386.0
View
TLS2_k127_60697_2
COG0589 Universal stress protein UspA and related nucleotide-binding proteins
-
-
-
0.0000000000000000000000000000000000000000000000000000002384
199.0
View
TLS2_k127_60697_3
Tripartite ATP-independent periplasmic transporters, DctQ component
-
-
-
0.00000000000000000000000000000004237
132.0
View
TLS2_k127_60697_4
Bacterial extracellular solute-binding protein, family 7
-
-
-
0.000009161
49.0
View
TLS2_k127_6071288_0
Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K04066
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719
528.0
View
TLS2_k127_6071288_1
Belongs to the 'phage' integrase family. XerC subfamily
K03733
-
-
0.00000000000000000000001664
103.0
View
TLS2_k127_60818_0
His Kinase A (phosphoacceptor) domain
K13587
-
2.7.13.3
6.291e-274
867.0
View
TLS2_k127_60818_1
Sulfotransferase family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000009191
275.0
View
TLS2_k127_60818_2
Flagellar biosynthesis protein, FliO
-
-
-
0.0000000000008865
73.0
View
TLS2_k127_6086976_0
DegT/DnrJ/EryC1/StrS aminotransferase family
K00812
-
2.6.1.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079
516.0
View
TLS2_k127_6086976_1
Domain of unknown function (DUF892)
-
-
-
0.00000000000000000000000000000000000000000000000000000000003346
212.0
View
TLS2_k127_6086976_2
damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
K03702
-
-
0.000000000000000000000000000000000000000000115
165.0
View
TLS2_k127_6086976_3
Putative member of DMT superfamily (DUF486)
K09922
-
-
0.00000000000000000000000000000000000000002948
157.0
View
TLS2_k127_6086976_4
Polyketide cyclase / dehydrase and lipid transport
-
-
-
0.0000000000000000000000000000000000000001048
161.0
View
TLS2_k127_6086976_5
Protein of unknown function (DUF3775)
-
-
-
0.000000000000009219
80.0
View
TLS2_k127_6086976_6
-
-
-
-
0.00001442
49.0
View
TLS2_k127_6091155_0
Prolyl oligopeptidase, N-terminal beta-propeller domain
K01354
GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564
3.4.21.83
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089
344.0
View
TLS2_k127_6091155_1
Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K04564
-
1.15.1.1
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109
340.0
View
TLS2_k127_6091155_2
Isochorismatase hydrolase
-
-
-
0.000000000000000000000000000000000000000000000471
172.0
View
TLS2_k127_6091155_3
of ABC transporters with duplicated ATPase
K06158
-
-
0.000000000000000000000000000000000000000000002232
170.0
View
TLS2_k127_6099975_0
DDE superfamily endonuclease
-
-
-
9.467e-194
614.0
View
TLS2_k127_6099975_1
Winged helix-turn helix
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436
305.0
View
TLS2_k127_6150806_0
ferredoxin--NADP reductase
K00384
-
1.8.1.9
0.00000000000000000000000000000000000000000000000000000000482
199.0
View
TLS2_k127_6150806_1
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
-
-
-
0.0000000000000000000000005546
118.0
View
TLS2_k127_6176850_0
Isocitrate/isopropylmalate dehydrogenase
K00031
-
1.1.1.42
2.233e-213
668.0
View
TLS2_k127_6176850_1
Ion transport protein
K10716
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824
358.0
View
TLS2_k127_6176850_2
Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
K02533
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000002135
276.0
View
TLS2_k127_6176850_3
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K01872
GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576
6.1.1.7
0.000000000000000000000008439
103.0
View
TLS2_k127_6187171_0
Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K03684
-
3.1.13.5
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601
366.0
View
TLS2_k127_6187171_1
-
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741
302.0
View
TLS2_k127_6187171_2
MerR HTH family regulatory protein
K18997
-
-
0.0000000000000000000000004553
111.0
View
TLS2_k127_6187171_3
DnaJ C terminal domain
-
-
-
0.000000000000000000008221
93.0
View
TLS2_k127_6187171_4
Protein of unknown function (DUF2905)
-
-
-
0.000000000008144
71.0
View
TLS2_k127_6208006_0
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
K03070
GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680
-
5.417e-207
650.0
View
TLS2_k127_6208006_1
Protein-tyrosine phosphatase, low molecular weight
K03741
-
1.20.4.1
0.000000000000000000000000000000000000000000000000000000000000000000000006174
253.0
View
TLS2_k127_6208006_2
peptidyl-prolyl isomerase
K01802,K03769
-
5.2.1.8
0.00000000000000000000000000000000000000000000000000000004427
203.0
View
TLS2_k127_6208006_3
Helix-turn-helix domain
K03892
-
-
0.00000000000000000000000000000000005321
136.0
View
TLS2_k127_62210_0
NmrA-like family
K01784
-
5.1.3.2
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647
484.0
View
TLS2_k127_62210_1
Lytic murein transglycosylase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886
403.0
View
TLS2_k127_62210_2
UTP-glucose-1-phosphate uridylyltransferase
K00963
-
2.7.7.9
0.0000000000000000000000000000000000000000000000000000000000000000000000000000003023
267.0
View
TLS2_k127_62210_3
Transglycosylase SLT domain
K00786,K08305
-
-
0.0000000000000000000000000000001204
131.0
View
TLS2_k127_6246509_0
Protein kinase domain
K12132
-
2.7.11.1
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278
402.0
View
TLS2_k127_6246509_2
Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K03307
-
-
0.0000000000000000008793
91.0
View
TLS2_k127_626353_0
OmpW family
K07275
-
-
0.00000000000000000000000000000000000000000000000000000000000007339
222.0
View
TLS2_k127_626353_1
Crp-like helix-turn-helix domain
K01420
-
-
0.0000000000000000000000000000000001443
144.0
View
TLS2_k127_626353_2
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K02469
-
5.99.1.3
0.000000000000000000000008865
102.0
View
TLS2_k127_6269294_0
Elongation factor G, domain IV
K02355
-
-
8.727e-293
911.0
View
TLS2_k127_6269294_1
Lytic murein transglycosylase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282
366.0
View
TLS2_k127_6269294_2
biosynthesis protein
-
-
-
0.0000000000000000000000000000000000001807
147.0
View
TLS2_k127_6269294_3
Domain present in phytochromes and cGMP-specific phosphodiesterases.
-
-
-
0.000000000002071
78.0
View
TLS2_k127_6269294_4
histidine kinase HAMP region domain protein
K03406
-
-
0.0000000005161
70.0
View
TLS2_k127_6269294_5
COG2199 FOG GGDEF domain
K13069
-
2.7.7.65
0.00001378
50.0
View
TLS2_k127_6377750_0
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
K00566
-
2.8.1.13
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219
520.0
View
TLS2_k127_6377750_1
two component transcriptional regulator
K02483,K13584
GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201
439.0
View
TLS2_k127_6377750_10
Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K00575
-
2.1.1.80
0.0000000000000000007561
89.0
View
TLS2_k127_6377750_11
catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
K03412
-
3.1.1.61,3.5.1.44
0.000000000000000805
80.0
View
TLS2_k127_6377750_13
Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K00575
-
2.1.1.80
0.00000008084
56.0
View
TLS2_k127_6377750_14
Transposase
-
-
-
0.000877
44.0
View
TLS2_k127_6377750_2
ubiE/COQ5 methyltransferase family
K00570
-
2.1.1.17,2.1.1.71
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382
297.0
View
TLS2_k127_6377750_3
Belongs to the UPF0234 family
K09767
-
-
0.000000000000000000000000000000000000000000000000000000000000000000004125
239.0
View
TLS2_k127_6377750_4
cheY-homologous receiver domain
K03413
-
-
0.000000000000000000000000000000000000000000000000000003179
192.0
View
TLS2_k127_6377750_5
Protein of unknown function (DUF1153)
-
-
-
0.00000000000000000000000000000000000000000000000552
173.0
View
TLS2_k127_6377750_6
catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
K03412
-
3.1.1.61,3.5.1.44
0.000000000000000000000000000000000000000004546
160.0
View
TLS2_k127_6377750_7
Flagellar FliJ protein
-
-
-
0.0000000000000000000000000000000007559
134.0
View
TLS2_k127_6377750_8
catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
K03412
-
3.1.1.61,3.5.1.44
0.00000000000000000000000000000007137
132.0
View
TLS2_k127_6377750_9
Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K00575
-
2.1.1.80
0.000000000000000000000171
101.0
View
TLS2_k127_6469889_0
Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
K00097
-
1.1.1.262
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314
394.0
View
TLS2_k127_6469889_1
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
K02528
GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360
2.1.1.182
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525
346.0
View
TLS2_k127_6469889_2
Essential for recycling GMP and indirectly, cGMP
K00942
-
2.7.4.8
0.00000000000000000000000000000000000000000000000000000000000000000000000002738
258.0
View
TLS2_k127_6469889_3
Domain of unknown function (DUF1732)
-
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464
-
0.00000000000000000000000000000000000000000000000000000000000000008497
229.0
View
TLS2_k127_6549661_0
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K00147
GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114
1.2.1.41
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289
556.0
View
TLS2_k127_6549661_1
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K00969
-
2.7.7.18
0.00000000000000000000000000000000000000000000000000000000000006447
226.0
View
TLS2_k127_6549661_2
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K00931
-
2.7.2.11
0.0000001623
53.0
View
TLS2_k127_6553388_0
Patatin phospholipase
K07001
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792
514.0
View
TLS2_k127_6553388_1
Major Facilitator Superfamily
K08224
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079
493.0
View
TLS2_k127_6553388_2
KR domain
K00019
-
1.1.1.30
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009853
383.0
View
TLS2_k127_6553388_3
Bacterial regulatory helix-turn-helix protein, lysR family
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492
367.0
View
TLS2_k127_6553388_4
Redoxin
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004896
287.0
View
TLS2_k127_6553388_5
Cupin domain
-
-
-
0.00000000000000000000000000000000000000000001445
167.0
View
TLS2_k127_6553388_6
PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
-
-
-
0.00000000000000000000000000000009819
126.0
View
TLS2_k127_6554143_0
Cytochrome c
-
-
-
5.459e-269
850.0
View
TLS2_k127_6557540_0
Major Facilitator Superfamily
K08223
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965
473.0
View
TLS2_k127_6557540_1
Calcineurin-like phosphoesterase superfamily domain
K07098
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448
468.0
View
TLS2_k127_6557540_2
CDP-archaeol synthase
K19664
-
2.7.7.67
0.0000000000000000000000000000000000000000000000002745
180.0
View
TLS2_k127_6557969_0
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K01876
-
6.1.1.12
7.002e-309
955.0
View
TLS2_k127_6557969_1
Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K03684
-
3.1.13.5
0.000000000000000000000000000000000000000000000000000000000001931
213.0
View
TLS2_k127_6557969_2
Ceramidase
-
-
-
0.00000000000000000000000000000000000000000000000000008823
197.0
View
TLS2_k127_6565366_0
Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
K00275
GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617
1.4.3.5
0.0000000000000000000000000000000000000000000000000000000000000000000000000000001027
271.0
View
TLS2_k127_6565366_1
Protein of unknown function (DUF1499)
-
-
-
0.000000000000000000000000000000000000000000000007241
183.0
View
TLS2_k127_6565366_2
Metallo-beta-lactamase superfamily
K01069
-
3.1.2.6
0.0000000000000000000000000000000000000000000005418
169.0
View
TLS2_k127_6569547_0
AcrB/AcrD/AcrF family
K18138,K18307
-
-
5.843e-211
668.0
View
TLS2_k127_6569547_1
Biotin carboxylase C-terminal domain
K01965
GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681
6.4.1.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956
441.0
View
TLS2_k127_6572072_0
ester cyclase
-
-
-
0.000000000000000000000000000008554
128.0
View
TLS2_k127_6572072_1
-
-
-
-
0.0000000000000000000001647
105.0
View
TLS2_k127_6572072_2
-
-
-
-
0.0000000000000000001122
93.0
View
TLS2_k127_6572072_3
-
-
-
-
0.0000002101
55.0
View
TLS2_k127_6573497_0
Belongs to the SEDS family
K03588
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112
404.0
View
TLS2_k127_6573497_1
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K02563
-
2.4.1.227
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252
396.0
View
TLS2_k127_6579970_0
Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily
K00239
-
1.3.5.1,1.3.5.4
6.612e-209
654.0
View
TLS2_k127_6579970_1
histidine kinase A domain protein
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568
457.0
View
TLS2_k127_6579970_2
Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K00240
-
1.3.5.1,1.3.5.4
0.0000000000000000000000000000000000000000000000000000000002117
204.0
View
TLS2_k127_6579970_3
cheY-homologous receiver domain
-
-
-
0.00000000000000000000007959
109.0
View
TLS2_k127_6581330_0
Pyruvate phosphate dikinase, PEP/pyruvate binding domain
K01006
-
2.7.9.1
5.708e-248
777.0
View
TLS2_k127_6581330_1
Cell Wall Hydrolase
-
-
-
0.000000000000000000000000000000000000001345
158.0
View
TLS2_k127_6586965_0
COG2801 Transposase and inactivated derivatives
K07497
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056
464.0
View
TLS2_k127_6586965_1
COG2963 Transposase and inactivated derivatives
-
-
-
0.000000000000000000000000000000000000000000000002313
174.0
View
TLS2_k127_6586965_2
NACHT nucleoside triphosphatase
K12132
-
2.7.11.1
0.00000000000267
72.0
View
TLS2_k127_6591644_0
phospho-2-dehydro-3-deoxyheptonate aldolase
K01626
GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
2.5.1.54
2.078e-239
746.0
View
TLS2_k127_6591644_1
Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
K00383
GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700
1.8.1.7
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066
517.0
View
TLS2_k127_6591644_2
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
K06048
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121
515.0
View
TLS2_k127_6591644_3
Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K01807
-
5.3.1.6
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004462
292.0
View
TLS2_k127_6591644_4
VIT family
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000833
299.0
View
TLS2_k127_6591644_5
KR domain
K00038
-
1.1.1.53
0.00000000000000000000000000000000000000000000000000000000000000000000000000000007217
274.0
View
TLS2_k127_6591644_6
Domain of unknown function (DUF4440)
-
-
-
0.00000007741
57.0
View
TLS2_k127_6591644_7
SnoaL-like domain
K01822
-
5.3.3.1
0.000003965
49.0
View
TLS2_k127_6594614_0
Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
K02863
GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521
362.0
View
TLS2_k127_6594614_1
Participates in transcription elongation, termination and antitermination
K02601
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777
302.0
View
TLS2_k127_6594614_2
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K02867
GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000000000000000000000000000000000000000000007236
227.0
View
TLS2_k127_6594614_3
Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
K03073
-
-
0.000000000000000009085
84.0
View
TLS2_k127_6594614_4
-
-
-
-
0.00000006636
55.0
View
TLS2_k127_6594614_5
Evidence 5 No homology to any previously reported sequences
-
-
-
0.0000007482
53.0
View
TLS2_k127_6602811_0
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K00410,K00412
-
-
1.323e-196
624.0
View
TLS2_k127_6602811_1
Cytochrome c1
K00413
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001544
287.0
View
TLS2_k127_6602811_2
Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates
K00772
-
2.4.2.28
0.00000000000000000000000000000000000000000000000000000000000000000000000009591
259.0
View
TLS2_k127_6602811_3
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K00411
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
1.10.2.2
0.000000000000000000000000000000000000000000004274
164.0
View
TLS2_k127_6602811_4
protein conserved in bacteria
-
-
-
0.000000000000000000000001372
115.0
View
TLS2_k127_6604397_0
Periplasmic binding protein
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321
411.0
View
TLS2_k127_6604397_1
Lactonase, 7-bladed beta-propeller
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423
400.0
View
TLS2_k127_6604397_2
Belongs to the bacterial glucokinase family
K00845
-
2.7.1.2
0.00000000000000000000000000000000000000000009471
168.0
View
TLS2_k127_6604397_3
Copper chaperone PCu(A)C
K09796
-
-
0.000000000000000000000000000000000000002513
157.0
View
TLS2_k127_6604397_4
COG3909 Cytochrome c556
-
-
-
0.00000000000000000000000316
108.0
View
TLS2_k127_6608864_0
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K01874
-
6.1.1.10
1.337e-251
785.0
View
TLS2_k127_6608864_1
AAA domain
K07028
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277
432.0
View
TLS2_k127_6608864_2
Belongs to the peptidase S11 family
K07258
-
3.4.16.4
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229
394.0
View
TLS2_k127_6608864_3
DNA polymerase III, delta subunit
K02341
-
2.7.7.7
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416
316.0
View
TLS2_k127_6608864_4
TatD related DNase
K03424
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000144
277.0
View
TLS2_k127_6608864_5
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K00943
GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576
2.7.4.9
0.0000000000000000000000000000000000000000000000000000000000000000004141
234.0
View
TLS2_k127_6608864_6
Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K03642
-
-
0.00000000000000000000000000000000000000000000000000000000000004278
227.0
View
TLS2_k127_6608864_7
Glutaredoxin
-
-
-
0.00000008098
59.0
View
TLS2_k127_6620202_0
Elongator protein 3 MiaB NifB
-
-
-
9.357e-303
938.0
View
TLS2_k127_6620202_1
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
K03695
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376
402.0
View
TLS2_k127_6620202_10
ASCH domain
-
-
-
0.000001335
53.0
View
TLS2_k127_6620202_2
COG1002 Type II restriction enzyme, methylase subunits
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375
399.0
View
TLS2_k127_6620202_3
Pfam:Methyltransf_26
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001192
283.0
View
TLS2_k127_6620202_4
Domain of unknown function (DUF4167)
-
-
-
0.0000000000000000000000000000000001546
138.0
View
TLS2_k127_6620202_5
Pfam:Methyltransf_26
-
-
-
0.000000000000000000000000000000005083
130.0
View
TLS2_k127_6620202_6
COG1002 Type II restriction enzyme, methylase subunits
-
-
-
0.00000000000000000000000002365
117.0
View
TLS2_k127_6620202_7
-
-
-
-
0.0000000000000000000000008789
107.0
View
TLS2_k127_6620202_8
-
-
-
-
0.00000000000000003386
84.0
View
TLS2_k127_6620202_9
type II restriction enzyme, methylase
-
-
-
0.0000004329
61.0
View
TLS2_k127_6629882_0
imidazoleglycerol-phosphate dehydratase
K00817,K01089,K01693
GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
2.6.1.9,3.1.3.15,4.2.1.19
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083
330.0
View
TLS2_k127_6629882_1
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K02501
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814
327.0
View
TLS2_k127_6629882_2
1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K01814
GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
5.3.1.16
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008454
283.0
View
TLS2_k127_6629882_3
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
K01419
-
3.4.25.2
0.00000000000000000000000000000000000000000001492
164.0
View
TLS2_k127_6629882_4
Protein of unknown function (DUF2628)
-
-
-
0.00000000000000000000000007154
113.0
View
TLS2_k127_6632514_0
Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
-
-
-
1.307e-275
854.0
View
TLS2_k127_6632514_1
Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
K07484
-
-
0.0000000000000000000000000000000000000000000000000000000000009399
211.0
View
TLS2_k127_6632514_2
Evidence 4 Homologs of previously reported genes of
K07483
-
-
0.0000000000000000000001184
104.0
View
TLS2_k127_6640695_0
Polysaccharide biosynthesis protein
K08679
-
5.1.3.6
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133
498.0
View
TLS2_k127_6640695_1
COG0607 Rhodanese-related sulfurtransferase
-
-
-
0.000000000000000000000000000000000000000000000002166
178.0
View
TLS2_k127_6640695_2
Tetratricopeptide repeat
-
-
-
0.000000000000000000000000000004768
133.0
View
TLS2_k127_6640695_3
TIR domain
-
-
-
0.0000000000000000000000000000141
128.0
View
TLS2_k127_6640695_4
Binds directly to 16S ribosomal RNA
K02968
-
-
0.00000000000000000000000002487
111.0
View
TLS2_k127_6640695_5
it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K02313
GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837
-
0.000000000000000002196
86.0
View
TLS2_k127_664857_0
ABC transporter transmembrane region
K02021,K06147,K11085
-
-
1.772e-200
642.0
View
TLS2_k127_664857_1
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K03179,K06125
-
2.5.1.39
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066
389.0
View
TLS2_k127_664857_2
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
K09761
-
2.1.1.193
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526
310.0
View
TLS2_k127_664857_3
glutamate--cysteine ligase
K01919
-
6.3.2.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758
306.0
View
TLS2_k127_664857_4
Inositol monophosphatase family
K01092
-
3.1.3.25
0.0000000000000000000000000000000000000000000000000000000000000000000000000000009204
273.0
View
TLS2_k127_664857_5
Domain of unknown function (DUF374)
K02527
-
2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15
0.000000000000000000000000000000000000000000000000000000000304
209.0
View
TLS2_k127_664857_6
Domain of unknown function (DUF4170)
-
-
-
0.0000000000000000000000000005564
116.0
View
TLS2_k127_6652090_0
Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
K03705
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008436
321.0
View
TLS2_k127_6652090_1
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K03687
GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363
-
0.00000000000000000000000000000000000000000000000000000001174
205.0
View
TLS2_k127_6652090_2
2OG-Fe(II) oxygenase superfamily
K03919
-
1.14.11.33
0.0000000000000000006336
86.0
View
TLS2_k127_6653893_0
phosphate-selective porin
K07221
-
-
0.0000000000000000000000000000000000000000000000000000006247
212.0
View
TLS2_k127_6653893_1
PFAM Phosphate-selective porin O and P
K07221
-
-
0.00000000000000000000000000000000000000000000000000001588
208.0
View
TLS2_k127_6653893_2
UbiH UbiF VisC COQ6
K03185
-
-
0.0000000000000000000000000000000002789
138.0
View
TLS2_k127_6663251_0
Belongs to the beta-ketoacyl-ACP synthases family
K14660
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707
509.0
View
TLS2_k127_6663251_1
Belongs to the UPF0758 family
K03630
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694
336.0
View
TLS2_k127_6663251_2
Methionine aminopeptidase
K01265
-
3.4.11.18
0.0000000000000000000000000000000000000000000000002197
176.0
View
TLS2_k127_6668273_0
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K03688
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663
606.0
View
TLS2_k127_6668273_1
D-isomer specific 2-hydroxyacid dehydrogenase
K00015
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
1.1.1.26
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403
554.0
View
TLS2_k127_6668273_2
FAD binding domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861
535.0
View
TLS2_k127_6668273_3
Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K13038,K21977
-
4.1.1.36,6.3.2.5
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225
496.0
View
TLS2_k127_6668273_4
ThiF family
K21029
-
2.7.7.80
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983
360.0
View
TLS2_k127_6668273_5
This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
K01520
GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576
3.6.1.23
0.00000000000000000000000000000000000000000000000000000008506
200.0
View
TLS2_k127_6668273_6
Bacterial SH3 domain
K01876
-
6.1.1.12
0.0000000000000000000000000000000003627
138.0
View
TLS2_k127_6668326_0
The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
K03076
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736
586.0
View
TLS2_k127_6668326_1
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K02988
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614
322.0
View
TLS2_k127_6668326_2
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K02933
GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000002789
273.0
View
TLS2_k127_6668326_3
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K02994
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904
-
0.00000000000000000000000000000000000000000000000000000000000000000004894
232.0
View
TLS2_k127_6668326_4
Binds to the 23S rRNA
K02876
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904
-
0.00000000000000000000000000000000000000000000000000000000001667
213.0
View
TLS2_k127_6668326_5
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K02931
GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000000000000000000000000000000000001919
200.0
View
TLS2_k127_6668326_6
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
K02881
GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904
-
0.000000000000000000000000000000000000000000005846
165.0
View
TLS2_k127_6668326_7
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K02954
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904
-
0.000000000000000000000000000000000000008092
146.0
View
TLS2_k127_6668326_8
Ribosomal protein L30
K02907
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904
-
0.000000000000000000001541
101.0
View
TLS2_k127_667426_0
Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587
539.0
View
TLS2_k127_667426_1
Belongs to the SIS family. GutQ KpsF subfamily
K06041
-
5.3.1.13
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662
394.0
View
TLS2_k127_6691421_0
Radical SAM
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857
500.0
View
TLS2_k127_6691421_1
Glycosyl transferase group 2 family protein
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802
300.0
View
TLS2_k127_6691421_2
Uncharacterized protein conserved in bacteria (DUF2064)
K09931
-
-
0.000000000000000000000000000000000000000000000000000002455
199.0
View
TLS2_k127_6691421_3
Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K03470
GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576
3.1.26.4
0.00000000000000000000000000002989
121.0
View
TLS2_k127_6691421_4
diguanylate cyclase
-
-
-
0.00000000000000000000183
97.0
View
TLS2_k127_6694423_0
redox protein regulator of disulfide bond formation
K07397
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000509
236.0
View
TLS2_k127_6694423_1
Leucine rich repeat
-
-
-
0.0000000000000000000000000000000000000000000000000000000005598
214.0
View
TLS2_k127_6694423_2
-
-
-
-
0.000000000000000000000000000000000001499
144.0
View
TLS2_k127_6694423_3
Belongs to the bacterial histone-like protein family
-
-
-
0.000000000000000000000000000000002915
132.0
View
TLS2_k127_6694423_5
Transglycosylase associated protein
-
-
-
0.00000000000000000000002505
102.0
View
TLS2_k127_6694423_6
COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
-
-
-
0.00000000000000000000004995
108.0
View
TLS2_k127_6694423_7
-
-
-
-
0.00000000002873
65.0
View
TLS2_k127_6694423_8
-
-
-
-
0.000000005052
59.0
View
TLS2_k127_6694423_9
-
-
-
-
0.000008665
53.0
View
TLS2_k127_6704016_0
NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
-
-
-
0.0
1289.0
View
TLS2_k127_6704016_1
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
-
-
-
0.0
1013.0
View
TLS2_k127_6704016_2
Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit
K05561
-
-
6.086e-196
623.0
View
TLS2_k127_6704016_3
Belongs to the Dps family
K04047
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000003888
254.0
View
TLS2_k127_6704016_4
Multisubunit Na H antiporter, MnhE subunit
K05562
-
-
0.00000000000000000000000000000000000000000000000000000000000000000001215
236.0
View
TLS2_k127_6704016_5
Antibiotic biosynthesis monooxygenase
-
-
-
0.0000000000000000000000000000000000000000000008542
167.0
View
TLS2_k127_6704016_6
COG1320 Multisubunit Na H antiporter, MnhG subunit
K05564
-
-
0.000000000000000000000000000000000000000000001665
167.0
View
TLS2_k127_6704016_7
Multisubunit Na H antiporter, MnhC subunit
K05560
-
-
0.00000000000000000000000000000000000000007289
157.0
View
TLS2_k127_6704016_8
Multiple resistance and pH regulation protein F (MrpF / PhaF)
K05563
-
-
0.00000000000000000000000000002048
122.0
View
TLS2_k127_6712220_0
Peptidase dimerisation domain
K01436
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489
575.0
View
TLS2_k127_6712220_1
Belongs to the RNase T2 family
K01166,K01169
-
3.1.27.1,3.1.27.6
0.0000000000000000000000000000000000000000000000000000000008605
210.0
View
TLS2_k127_6712220_2
Cold-shock
K03704
-
-
0.000000000000000000000000000000007296
130.0
View
TLS2_k127_6712220_3
Glycine cleavage system T protein
K00605
GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204
2.1.2.10
0.00000000000000000004326
93.0
View
TLS2_k127_6712220_4
Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K03642
-
-
0.00000000000002643
80.0
View
TLS2_k127_6715510_0
DNA ligase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876
478.0
View
TLS2_k127_6715510_1
Penicillin-Binding Protein C-terminus Family
K05367
-
2.4.1.129
0.0000000000000000000000003912
108.0
View
TLS2_k127_6715510_2
Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K06168
-
2.8.4.3
0.0000000001991
64.0
View
TLS2_k127_6715748_0
flagellar motor protein
K02557
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185
395.0
View
TLS2_k127_6715748_1
Inositol monophosphatase
K01092
-
3.1.3.25
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851
365.0
View
TLS2_k127_6715748_2
MotA TolQ ExbB proton channel family
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094
358.0
View
TLS2_k127_6715748_3
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K02356
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889
311.0
View
TLS2_k127_6715748_4
Protein of unknown function (DUF861)
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006804
276.0
View
TLS2_k127_6725631_0
Belongs to the folylpolyglutamate synthase family
K11754
-
6.3.2.12,6.3.2.17
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565
484.0
View
TLS2_k127_6725631_1
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K01963
-
2.1.3.15,6.4.1.2
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729
443.0
View
TLS2_k127_6725631_2
Belongs to the thioredoxin family
K03671
-
-
0.0000000000000000000000000000000000000001007
153.0
View
TLS2_k127_6725631_3
Belongs to the helicase family. UvrD subfamily
K16898
-
3.6.4.12
0.000000000000000000000000000386
115.0
View
TLS2_k127_6725631_4
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
K01695
-
4.2.1.20
0.0000006188
53.0
View
TLS2_k127_672595_0
AI-2E family transporter
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029
372.0
View
TLS2_k127_672595_1
Domain of Unknown Function (DUF1206)
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000004577
239.0
View
TLS2_k127_6736004_0
ArgJ family
K00620
GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
2.3.1.1,2.3.1.35
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001989
282.0
View
TLS2_k127_6736004_1
Methyltransferase domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000006228
272.0
View
TLS2_k127_6736004_2
NUDIX domain
K03574
GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360
3.6.1.55
0.00000000000000000000000000000000000000000000000000007261
190.0
View
TLS2_k127_6736004_3
Flp/Fap pilin component
K02651
-
-
0.0008134
46.0
View
TLS2_k127_67676_0
Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
K04094
GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363
2.1.1.74
1.163e-219
691.0
View
TLS2_k127_67676_1
Protein of unknown function (DUF1097)
-
-
-
0.000000000000000000000000000000000000000000000000002272
198.0
View
TLS2_k127_67676_2
PFAM Squalene phytoene synthase
K02291,K18163
-
2.5.1.32,2.5.1.99
0.000000000000000000000000000000000000000000000000003875
191.0
View
TLS2_k127_67676_3
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K03074
-
-
0.000000000000000000000000000000002361
132.0
View
TLS2_k127_6774738_0
Protease II
K01354
GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564
3.4.21.83
1.537e-213
675.0
View
TLS2_k127_6774738_1
ROS/MUCR transcriptional regulator protein
-
-
-
0.000000000000000000000000000000000000000000000000000000000236
207.0
View
TLS2_k127_6774738_2
Belongs to the MsrB Met sulfoxide reductase family
K07305
-
1.8.4.12
0.00000000000000000003248
90.0
View
TLS2_k127_6774738_3
Belongs to the MsrB Met sulfoxide reductase family
K07305
-
1.8.4.12
0.000000001142
65.0
View
TLS2_k127_6774738_4
methionine sulfoxide reductase
K07305
-
1.8.4.12
0.00000001584
60.0
View
TLS2_k127_6776267_0
Stimulus-sensing domain
K14980
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
2.7.13.3
5.562e-212
674.0
View
TLS2_k127_6776267_1
Transcriptional regulatory protein, C terminal
K14981
GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303
398.0
View
TLS2_k127_6776267_10
Prokaryotic cytochrome b561
-
-
-
0.0000000194
59.0
View
TLS2_k127_6776267_2
VIT family
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927
317.0
View
TLS2_k127_6776267_3
pyridoxamine 5'-phosphate
K07226
-
-
0.00000000000000000000000000000000000000000000000000000000000000004969
233.0
View
TLS2_k127_6776267_4
PTS system fructose IIA component
K02793
-
2.7.1.191
0.000000000000000000000000000000000000000000000000000000007678
202.0
View
TLS2_k127_6776267_5
Tyrosine phosphatase family
-
-
-
0.00000000000000000000000000000000000000000000001648
179.0
View
TLS2_k127_6776267_6
cytochrome
-
-
-
0.000000000000000000000000000000000000007328
148.0
View
TLS2_k127_6776267_7
HPr Serine kinase C-terminal domain
K06023
-
-
0.00000000000000000000000000004476
125.0
View
TLS2_k127_6776267_8
PTS HPr component phosphorylation site
K11189
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702
-
0.0000000000000000000000000761
111.0
View
TLS2_k127_6776267_9
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
K01596
GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533
4.1.1.32
0.000000001499
64.0
View
TLS2_k127_677893_0
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force
K15987
-
3.6.1.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023
457.0
View
TLS2_k127_677893_1
Ubiquinol-cytochrome C chaperone
K17662
-
-
0.00000000000000000000000000009277
122.0
View
TLS2_k127_677893_2
SmpA / OmlA family
-
-
-
0.000000000000000000000000009454
117.0
View
TLS2_k127_6791206_0
Reversible hydration of carbon dioxide
K01673
-
4.2.1.1
0.0000000000000000000000000000000000000000000000000000000000004764
218.0
View
TLS2_k127_6791206_1
Linear amide C-N hydrolases, choloylglycine hydrolase family
K01442
-
3.5.1.24
0.000000000000000000000000000000000000000000000000002479
187.0
View
TLS2_k127_6791206_2
Mycolic acid cyclopropane synthetase
K00574
-
2.1.1.79
0.000000000000000000000000000000004431
130.0
View
TLS2_k127_6791206_3
-
-
-
-
0.000000000000000002567
87.0
View
TLS2_k127_6792076_0
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K00281,K00283
-
1.4.4.2
1.714e-233
728.0
View
TLS2_k127_6792076_1
Glycine cleavage system T protein
K00605
GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204
2.1.2.10
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798
410.0
View
TLS2_k127_6792076_2
The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
K02437
-
-
0.000000000000000000000000000000000000000000000000001502
188.0
View
TLS2_k127_6794901_0
Belongs to the peptidase S11 family
K01286
-
3.4.16.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846
299.0
View
TLS2_k127_6794901_1
TIR domain
-
-
-
0.00000000000000000000003471
103.0
View
TLS2_k127_6794901_2
-
-
-
-
0.00000000002217
72.0
View
TLS2_k127_6810431_0
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K00937
-
2.7.4.1
7.925e-321
994.0
View
TLS2_k127_6810431_1
Ppx/GppA phosphatase family
K01524
-
3.6.1.11,3.6.1.40
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492
484.0
View
TLS2_k127_6829931_0
Transcription elongation factor
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000007929
224.0
View
TLS2_k127_6829931_1
-
-
-
-
0.00000000000000000000000000000000000009247
156.0
View
TLS2_k127_6829931_2
Rdx family
K07401
-
-
0.00000000000000000000000000000000006324
136.0
View
TLS2_k127_6829931_3
Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)
-
-
-
0.0000000000000000000000000001302
119.0
View
TLS2_k127_6829931_4
Ammonium Transporter Family
K03320
-
-
0.00000000000003502
72.0
View
TLS2_k127_6851852_0
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
K03545
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289
546.0
View
TLS2_k127_6851852_1
Pyridoxal-phosphate dependent enzyme
K01738
GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
2.5.1.47
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651
467.0
View
TLS2_k127_6851852_2
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
K01358
-
3.4.21.92
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773
350.0
View
TLS2_k127_6851852_3
ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K03544
GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015
338.0
View
TLS2_k127_6901842_0
Domain of unknown function DUF21
K03699
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345
392.0
View
TLS2_k127_6901842_1
DnaJ molecular chaperone homology domain
-
-
-
0.000000000000000000000000000000000000000000000000000000002793
211.0
View
TLS2_k127_6901842_2
BolA-like protein
K05527,K22066
GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564
-
0.0000000000000000000000482
111.0
View
TLS2_k127_6901842_3
Cobaltochelatase CobS subunit N terminal
K09882
-
6.6.1.2
0.00002354
48.0
View
TLS2_k127_6913_0
Involved in the TonB-independent uptake of proteins
K03641
-
-
2.321e-201
636.0
View
TLS2_k127_6913_1
Belongs to the ompA family
K03640
-
-
0.00000000000000000000000000000000000000000000000000000000000001701
219.0
View
TLS2_k127_6913_2
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
K04075
-
6.3.4.19
0.0000000000000000000000000000000000000000000000000000000001292
215.0
View
TLS2_k127_6913_3
Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
-
-
-
0.0000000000000000000000000000000000000000000001673
181.0
View
TLS2_k127_6913_4
Membrane
-
-
-
0.0000000004921
60.0
View
TLS2_k127_6937348_0
Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K01714
GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704
4.3.3.7
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659
436.0
View
TLS2_k127_6937348_1
Evidence 4 Homologs of previously reported genes of
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564
310.0
View
TLS2_k127_6937348_2
UreE urease accessory protein, C-terminal domain
K21929
-
3.2.2.27
0.000000000000000000000000000000000000000000000000000000000000000000000000000000002865
276.0
View
TLS2_k127_6937348_3
Transglycosylase SLT domain
K08309
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000006638
279.0
View
TLS2_k127_6937348_4
the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
K03664
-
-
0.00000000000000000000000000000000000000000000000000000000111
204.0
View
TLS2_k127_6937348_5
Redoxin domain protein
-
-
-
0.000000000000000000000000000000000000000000000000000000003017
208.0
View
TLS2_k127_6937348_6
Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
K03060
-
2.7.7.6
0.00000000000000000000000000000000000000000004789
173.0
View
TLS2_k127_6937348_7
Protein of unknown function (DUF3775)
-
-
-
0.0000000000000000000000000000000000000007331
151.0
View
TLS2_k127_6937348_8
7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
K00950,K13940
-
2.7.6.3,4.1.2.25
0.000000000000000000000000000000000000006183
152.0
View
TLS2_k127_6937348_9
In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K00951,K01139
-
2.7.6.5,3.1.7.2
0.00000000000000000000000000000192
120.0
View
TLS2_k127_6951689_0
MoeA N-terminal region (domain I and II)
K03750
-
2.10.1.1
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867
468.0
View
TLS2_k127_6951689_1
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
K03752
-
2.7.7.77
0.00000000000000000000000000000000000000000000000000000005637
202.0
View
TLS2_k127_6951689_2
molybdopterin-guanine dinucleotide biosynthesis protein
K03753
GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363
-
0.00000000000000000000000000000000000000000000000000001317
195.0
View
TLS2_k127_6951689_3
Amino acid ABC transporter substrate-binding protein
K02030
-
-
0.000000000000000000000000000000000000001668
161.0
View
TLS2_k127_6951689_4
Formate dehydrogenase subunit alpha
-
-
-
0.00000000000001318
74.0
View
TLS2_k127_6969563_0
Formate--tetrahydrofolate ligase
K01938
-
6.3.4.3
3.815e-213
666.0
View
TLS2_k127_6969563_1
PFAM aminotransferase class V
K00830
-
2.6.1.44,2.6.1.45,2.6.1.51
1.017e-197
623.0
View
TLS2_k127_6969563_2
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
K00018
GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464
1.1.1.29
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664
497.0
View
TLS2_k127_6969563_3
Methylene-tetrahydromethanopterin dehydrogenase, N-terminal
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739
400.0
View
TLS2_k127_6969563_4
PFAM Formiminotransferase-cyclodeaminase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000003417
252.0
View
TLS2_k127_7011478_0
ABC transporter
K02471
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187
346.0
View
TLS2_k127_7011478_1
phosphohistidine phosphatase, SixA
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000002259
241.0
View
TLS2_k127_7017520_0
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K00573
-
2.1.1.77
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317
349.0
View
TLS2_k127_7017520_1
Protein of unknown function (DUF541)
K09807
GO:0005575,GO:0005623,GO:0042597,GO:0044464
-
0.00000000000000000000000000000000000000000000005081
180.0
View
TLS2_k127_703254_0
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
K02836
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254
487.0
View
TLS2_k127_703254_1
Polymer-forming cytoskeletal
-
-
-
0.00000000000000000000000000000000000000000000006747
175.0
View
TLS2_k127_703254_2
Penicillin-binding protein OB-like domain
K05366
-
2.4.1.129,3.4.16.4
0.000000000004231
69.0
View
TLS2_k127_7085952_0
Histidine kinase
K11527
-
2.7.13.3
8.92e-205
658.0
View
TLS2_k127_7085952_1
Adenylyl- / guanylyl cyclase, catalytic domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000001625
279.0
View
TLS2_k127_7085952_2
COG1073 Hydrolases of the alpha beta superfamily
K06889
-
-
0.000000000000000000007153
94.0
View
TLS2_k127_7087966_0
glycosyl transferase group 1
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185
441.0
View
TLS2_k127_7087966_1
Calcineurin-like phosphoesterase superfamily domain
-
-
-
0.00000000000000000000000000000000000001238
146.0
View
TLS2_k127_7087966_2
Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
-
-
-
0.0002964
44.0
View
TLS2_k127_7150026_0
Transglycosylase associated protein
-
-
-
0.000000000000000000000000000001862
122.0
View
TLS2_k127_7150026_1
Bacterial protein of unknown function (DUF937)
-
-
-
0.000000000000000000000000000006211
124.0
View
TLS2_k127_7150026_2
-
-
-
-
0.000000000000000002126
88.0
View
TLS2_k127_7159269_0
Binding-protein-dependent transport system inner membrane component
K02011
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837
533.0
View
TLS2_k127_7159269_1
Bacterial extracellular solute-binding protein
K02055
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000004453
278.0
View
TLS2_k127_7159269_2
AsmA-like C-terminal region
K07289
-
-
0.0000000000000000000001014
114.0
View
TLS2_k127_7164386_0
COG0488 ATPase components of ABC transporters with duplicated ATPase domains
-
-
-
2.761e-202
634.0
View
TLS2_k127_7164386_1
Methyltransferase
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517
307.0
View
TLS2_k127_7164386_2
Cobalamin synthesis protein cobW C-terminal domain
-
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000002756
262.0
View
TLS2_k127_7169908_0
Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
K03596
-
-
0.0
1001.0
View
TLS2_k127_7169908_1
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K07304
-
1.8.4.11
0.000000000000000000000000000000000000000000000000000000000001279
214.0
View
TLS2_k127_7169908_2
-
-
-
-
0.000000001376
64.0
View
TLS2_k127_7188221_0
histidine kinase A domain protein
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000003258
259.0
View
TLS2_k127_7242425_0
PD-(D/E)XK nuclease superfamily
K16899
-
3.6.4.12
7.063e-270
865.0
View
TLS2_k127_7242425_1
Belongs to the helicase family. UvrD subfamily
K16898
-
3.6.4.12
6.961e-259
836.0
View
TLS2_k127_7242425_2
PFAM Nucleotidyl transferase
K00966,K00992
-
2.7.7.13,2.7.7.99
0.00000000000000000000000000000000000000000000647
166.0
View
TLS2_k127_7251442_0
-
-
-
-
0.00000000000000000000000000000000000214
145.0
View
TLS2_k127_7251442_1
Phage integrase family
-
-
-
0.0000000000000000000001988
101.0
View
TLS2_k127_7297121_0
KR domain
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274
394.0
View
TLS2_k127_7297121_2
metallophosphoesterase
-
-
-
0.0000000000000000000000000000000000000000000000000004306
191.0
View
TLS2_k127_7297121_3
-
-
-
-
0.0000000000000002247
91.0
View
TLS2_k127_7299718_0
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K18138
-
-
0.0
1324.0
View
TLS2_k127_7299718_1
Putative neutral zinc metallopeptidase
K07054
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269
370.0
View
TLS2_k127_7299718_2
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K03585
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814
302.0
View
TLS2_k127_7324758_0
Calcineurin-like phosphoesterase
-
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663
402.0
View
TLS2_k127_7324758_1
Belongs to the agmatine deiminase family
K10536
-
3.5.3.12
0.00000000000000000000000000000000000000000000341
166.0
View
TLS2_k127_7324758_2
Short repeat of unknown function (DUF308)
-
-
-
0.00001554
54.0
View
TLS2_k127_7370719_0
Beta-lactamase
K18988
-
3.4.16.4
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367
380.0
View
TLS2_k127_7370719_1
Belongs to the small heat shock protein (HSP20) family
K04080
-
-
0.00000000000000000000000000000001207
133.0
View
TLS2_k127_7370719_2
Protein of unknown function (DUF1150)
-
-
-
0.000000000000000002792
87.0
View
TLS2_k127_7400522_0
ATP:dephospho-CoA triphosphoribosyl transferase
K05966
-
2.4.2.52
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000711
289.0
View
TLS2_k127_7400522_1
Formaldehyde-activating enzyme (Fae)
K10713
-
4.2.1.147
0.00000000000000000000000000000000000000000000000000000000000000000000000000001436
261.0
View
TLS2_k127_7400522_2
RimK-like ATP-grasp domain
K05844
-
-
0.000000000000000000000000000000000000007168
149.0
View
TLS2_k127_7436024_0
Cytochrome P450
K15468
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788
580.0
View
TLS2_k127_7436024_1
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs
K05539
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113
393.0
View
TLS2_k127_7436024_2
Haloacid dehalogenase
K17686
-
3.6.3.54
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998
382.0
View
TLS2_k127_7436024_3
Cytochrome C oxidase, cbb3-type, subunit III
K19713
-
1.8.2.2
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149
315.0
View
TLS2_k127_766902_0
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K03979
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464
512.0
View
TLS2_k127_766902_1
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K00931
GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607
2.7.2.11
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023
483.0
View
TLS2_k127_766902_2
This protein binds to 23S rRNA in the presence of protein L20
K02888
GO:0003674,GO:0003735,GO:0005198
-
0.00000000000000000000000000000000000000001896
158.0
View
TLS2_k127_766902_3
Acetyltransferase (GNAT) domain
-
-
-
0.000000000000000000000000000000000000004254
151.0
View
TLS2_k127_766902_4
Belongs to the bacterial ribosomal protein bL27 family
K02899
GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904
-
0.00000000000000000000000000000000003801
135.0
View
TLS2_k127_766902_5
of tumorigenicity 14
K01312,K01324,K08670
-
3.4.21.109,3.4.21.34,3.4.21.4
0.000000002574
58.0
View
TLS2_k127_766902_6
receptor
-
-
-
0.000006976
50.0
View
TLS2_k127_784274_0
Catalyzes the reversible oxidation of malate to oxaloacetate
K00024
GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350
1.1.1.37
0.00000000000003699
72.0
View
TLS2_k127_784274_1
Cupin 2, conserved barrel domain protein
-
-
-
0.00000002093
63.0
View
TLS2_k127_784274_2
-
-
-
-
0.00003692
49.0
View
TLS2_k127_790886_0
ribonuclease BN
K07058
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991
309.0
View
TLS2_k127_790886_1
Integral membrane protein TerC family
-
-
-
0.0000000000000000000000000000000000000004649
151.0
View
TLS2_k127_790886_2
Belongs to the ompA family
K03286
-
-
0.000000000000000000000000000000005315
142.0
View
TLS2_k127_790886_3
sh3 domain protein
-
-
-
0.00000000000000000000001162
104.0
View
TLS2_k127_790886_4
Pentapeptide repeats (9 copies)
-
-
-
0.000000000000005442
83.0
View
TLS2_k127_790886_5
TonB C terminal
K03832
-
-
0.0000000008618
71.0
View
TLS2_k127_790886_6
hydrolases or acyltransferases (alpha beta hydrolase superfamily)
-
-
-
0.00000000115
60.0
View
TLS2_k127_790886_7
Protein of unknown function (DUF3096)
-
-
-
0.00000000346
61.0
View
TLS2_k127_790886_8
Resolvase, N terminal domain
-
-
-
0.0000008948
51.0
View
TLS2_k127_79313_0
Sodium:sulfate symporter transmembrane region
-
-
-
0.00000000000000000000001303
99.0
View
TLS2_k127_79313_1
AsmA family
K07289,K07290
-
-
0.000000009644
68.0
View
TLS2_k127_79313_2
Leucyl aminopeptidase (Aminopeptidase t)
-
-
-
0.000001546
59.0
View
TLS2_k127_84770_0
penicillin-binding protein
K05366
-
2.4.1.129,3.4.16.4
4.115e-203
644.0
View
TLS2_k127_937123_0
Cation transport ATPase (P-type)
K01537
-
3.6.3.8
0.0
1074.0
View
TLS2_k127_937123_1
nucleoside-triphosphate diphosphatase activity
K06287
-
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000000006346
277.0
View
TLS2_k127_937123_2
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K02518
-
-
0.0000000000000000000000000000000000000005198
149.0
View
TLS2_k127_937123_3
Cupin 2 conserved barrel domain protein
-
-
-
0.0000000000000000000000000005539
114.0
View
TLS2_k127_937123_4
Universal stress protein UspA
-
-
-
0.0000000000000000000000000007552
124.0
View
TLS2_k127_937123_5
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
K09862
-
-
0.00000000000001968
78.0
View
TLS2_k127_937123_6
Universal stress protein UspA
-
-
-
0.0000000000005705
70.0
View
TLS2_k127_937123_7
Resolvase
-
-
-
0.00000004247
56.0
View
TLS2_k127_9590_0
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K01681
GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363
4.2.1.3
4.447e-223
709.0
View
TLS2_k127_9590_1
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K02194
GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351
-
0.000000000000000000000000000000000000000000000000000000000000000000000000000004635
271.0
View
TLS2_k127_9590_2
once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system
K02193
-
3.6.3.41
0.000000000000000000000000000000000000000000000000000001157
199.0
View
TLS2_k127_965320_0
COG4772 Outer membrane receptor for Fe3 -dicitrate
K16091
-
-
9.618e-206
659.0
View
TLS2_k127_965320_1
May be involved in the transport of PQQ or its precursor to the periplasm
K06136
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304
406.0
View
TLS2_k127_965320_2
Histidine kinase
K07675
-
2.7.13.3
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833
331.0
View
TLS2_k127_965320_3
PFAM regulatory protein LuxR
-
-
-
0.0000000000000000000000000000000000000000000000000000000000000000000000000000001294
274.0
View
TLS2_k127_965320_4
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
K00788
-
2.5.1.3
0.0000000000000000000000000000000000000000000000000000007637
195.0
View
TLS2_k127_965320_5
CHAD
-
-
-
0.0000000000000000000000000000000000000000000005769
179.0
View
TLS2_k127_965320_6
Peptidase propeptide and YPEB domain
-
-
-
0.0000000000000000000000000001161
116.0
View
TLS2_k127_969228_0
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K00281,K00283
-
1.4.4.2
0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391
462.0
View
TLS2_k127_969228_1
alcohol dehydrogenase
K00001,K00043
-
1.1.1.1,1.1.1.61
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801
391.0
View
TLS2_k127_969228_2
Short-chain dehydrogenase reductase SDR
-
-
-
0.00000000000000000000000000000000000000000000000000000000000002301
222.0
View
TLS2_k127_969652_0
MMPL family
K07003
-
-
0.00000000000000000000000000000000000000000000000000000000000000000000000000000003664
287.0
View
TLS2_k127_988993_0
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K00383
GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700
1.8.1.7
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414
510.0
View
TLS2_k127_988993_1
Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K01807
-
5.3.1.6
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663
293.0
View
TLS2_k127_988993_2
Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress
K01091
-
3.1.3.18
0.000000000000000000000000000000000000000000000000000001289
210.0
View
TLS2_k127_988993_3
HNH endonuclease
-
-
-
0.00000000000000000000000000000000652
136.0
View
TLS2_k127_992701_0
Formylmethanofuran dehydrogenase, subunit B
K00201
-
1.2.7.12
0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937
514.0
View
TLS2_k127_992701_1
Formylmethanofuran dehydrogenase subunit A
K00200
-
1.2.7.12
0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083
452.0
View