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Overview

ID MAG04013
Name TLS2_bin.53
Sample SMP0104
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Desulfuromonadia
Order Desulfuromonadales
Family DASPGW01
Genus DASPGW01
Species
Assembly information
Completeness (%) 59.36
Contamination (%) 0.05
GC content (%) 61.0
N50 (bp) 7,240
Genome size (bp) 1,767,466

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1744

Gene name Description KEGG GOs EC E-value Score Sequence
TLS2_k127_1010539_0 Threonyl and Alanyl tRNA synthetase second additional domain K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1126.0
TLS2_k127_1010539_1 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 1.257e-224 703.0
TLS2_k127_1010539_2 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 572.0
TLS2_k127_1010539_3 Translation initiation factor IF-3, N-terminal domain K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000136 246.0
TLS2_k127_1010539_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002831 209.0
TLS2_k127_1010539_5 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000001886 115.0
TLS2_k127_109571_0 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 7.923e-197 622.0
TLS2_k127_109571_1 Sensor protein, DUF3365, HAMP and PAS domain-containing, heme-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 591.0
TLS2_k127_109571_2 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 522.0
TLS2_k127_109571_3 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 484.0
TLS2_k127_109571_4 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 417.0
TLS2_k127_109571_5 Formyl transferase, C-terminal domain K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 400.0
TLS2_k127_109571_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 378.0
TLS2_k127_109571_7 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001119 241.0
TLS2_k127_1110920_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1461.0
TLS2_k127_1110920_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 4.229e-230 721.0
TLS2_k127_1110920_2 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 7.195e-218 681.0
TLS2_k127_1110920_3 AMP binding - - - 0.00000000000000000000000000000000000000000000000000001641 192.0
TLS2_k127_1110920_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000004355 141.0
TLS2_k127_1110920_6 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000001971 138.0
TLS2_k127_1110920_8 BON domain - - - 0.0000000006801 60.0
TLS2_k127_1126114_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 2.833e-267 830.0
TLS2_k127_1126114_1 Histidyl-tRNA synthetase - - - 6.977e-195 613.0
TLS2_k127_1126114_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 439.0
TLS2_k127_1126114_3 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000003097 130.0
TLS2_k127_1164829_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1278.0
TLS2_k127_1164829_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 507.0
TLS2_k127_1164829_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000007021 233.0
TLS2_k127_1164829_3 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000005147 177.0
TLS2_k127_1164829_4 - - - - 0.00000000000000000000000000000000000000000001471 167.0
TLS2_k127_1164829_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000309 100.0
TLS2_k127_1164829_6 - - - - 0.00000000000000000004235 94.0
TLS2_k127_1164829_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000001604 54.0
TLS2_k127_1164829_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000007389 48.0
TLS2_k127_1238131_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.154e-214 672.0
TLS2_k127_1238131_1 Serine hydroxymethyltransferase K00600 - 2.1.2.1 4.738e-196 613.0
TLS2_k127_1238131_10 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000000000000000000000000593 218.0
TLS2_k127_1238131_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000008933 126.0
TLS2_k127_1238131_12 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000001615 98.0
TLS2_k127_1238131_2 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 560.0
TLS2_k127_1238131_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 526.0
TLS2_k127_1238131_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 519.0
TLS2_k127_1238131_5 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 469.0
TLS2_k127_1238131_6 Hsp90 protein K04079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 359.0
TLS2_k127_1238131_7 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 343.0
TLS2_k127_1238131_8 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 295.0
TLS2_k127_1238131_9 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000003451 254.0
TLS2_k127_1267127_0 Cysteine-rich domain K00113 - 1.1.5.3 8.624e-213 670.0
TLS2_k127_1267127_1 Sodium Bile acid symporter family K03325 - - 8.533e-203 635.0
TLS2_k127_1267127_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 355.0
TLS2_k127_1267127_3 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 290.0
TLS2_k127_1267127_4 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000007374 209.0
TLS2_k127_1267127_5 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000001188 207.0
TLS2_k127_1267127_6 PFAM regulatory protein, ArsR K03892 - - 0.0000000000000000000000000000000000002253 143.0
TLS2_k127_1267127_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000035 141.0
TLS2_k127_1293731_0 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 595.0
TLS2_k127_1293731_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 538.0
TLS2_k127_1293731_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 500.0
TLS2_k127_1293731_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 503.0
TLS2_k127_1293731_4 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 420.0
TLS2_k127_1293731_5 PFAM Phosphoglycerate mutase K08296 - - 0.0000000000000000000000000000000000000000000000000000000000000000001919 237.0
TLS2_k127_1293731_6 Domain of unknown function (DUF1974) K06445 - - 0.00000000000000000000000000000000000000000000005506 175.0
TLS2_k127_1293731_8 Pfam:DUF1602 - - - 0.00000006238 55.0
TLS2_k127_1293731_9 Transposase - - - 0.0000138 49.0
TLS2_k127_1311640_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.0 1004.0
TLS2_k127_1311640_1 Phospholipase D. Active site motifs. - - - 5.624e-245 775.0
TLS2_k127_1311640_2 Dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 449.0
TLS2_k127_1311640_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 429.0
TLS2_k127_1311640_4 ABC-2 family transporter protein K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 354.0
TLS2_k127_1311640_5 DoxX K15977 - - 0.00000000000000000000000000000000000000000000002004 174.0
TLS2_k127_1311640_7 - - - - 0.0000004889 54.0
TLS2_k127_1312508_0 ATPase family associated with various cellular activities (AAA) - - - 0.0 1268.0
TLS2_k127_1312508_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1170.0
TLS2_k127_1312508_2 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 552.0
TLS2_k127_1312508_3 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 349.0
TLS2_k127_1312508_4 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006171 263.0
TLS2_k127_1312508_5 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000000000000000000262 205.0
TLS2_k127_1314199_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 7.989e-275 857.0
TLS2_k127_1314199_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 521.0
TLS2_k127_1314199_2 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 463.0
TLS2_k127_1314199_3 - - - - 0.0000000000000000000000000000000000000004475 150.0
TLS2_k127_1314199_4 - - - - 0.000000000000000000000000000000004232 130.0
TLS2_k127_1319807_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.581e-259 801.0
TLS2_k127_1319807_1 Coenzyme A transferase K01027 - 2.8.3.5 5.605e-224 704.0
TLS2_k127_1319807_2 Bacterial extracellular solute-binding protein, family 7 - - - 4.312e-221 691.0
TLS2_k127_1319807_3 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 604.0
TLS2_k127_1319807_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 563.0
TLS2_k127_1319807_5 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 367.0
TLS2_k127_1319807_6 LUD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 360.0
TLS2_k127_1319807_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 295.0
TLS2_k127_1319807_8 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000002982 205.0
TLS2_k127_1319807_9 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000001488 186.0
TLS2_k127_1325573_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 574.0
TLS2_k127_1325573_1 DNA polymerase A domain K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 517.0
TLS2_k127_1325573_10 Bacterial SH3 domain - - - 0.000003112 61.0
TLS2_k127_1325573_2 response regulator K07664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 352.0
TLS2_k127_1325573_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K11389 - 1.2.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 316.0
TLS2_k127_1325573_4 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 293.0
TLS2_k127_1325573_5 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 284.0
TLS2_k127_1325573_6 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005276 273.0
TLS2_k127_1325573_7 - - - - 0.000000000000000000000000000000000000000000000000000000000007495 216.0
TLS2_k127_1325573_8 - - - - 0.00000000000000000000000000000053 124.0
TLS2_k127_1325573_9 Heavy-metal resistance - - - 0.00000000000000000001738 97.0
TLS2_k127_135197_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 3.049e-260 824.0
TLS2_k127_135197_1 B12 binding domain - - - 4.359e-243 769.0
TLS2_k127_135197_2 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 605.0
TLS2_k127_135197_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 339.0
TLS2_k127_135197_4 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006537 269.0
TLS2_k127_135197_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000002819 159.0
TLS2_k127_135197_6 Methyltransferase type 11 - - - 0.0000000000000000000000004946 116.0
TLS2_k127_135197_8 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.0000000005452 62.0
TLS2_k127_1423941_0 Putative nucleotidyltransferase substrate binding domain K07182 - - 8.055e-320 989.0
TLS2_k127_1423941_1 Sodium:solute symporter family - - - 6.563e-286 890.0
TLS2_k127_1423941_2 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 497.0
TLS2_k127_1423941_3 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000000119 133.0
TLS2_k127_1423941_4 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000002905 77.0
TLS2_k127_144547_0 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 8.267e-200 630.0
TLS2_k127_144547_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 585.0
TLS2_k127_144547_10 - - - - 0.000000000000000000000005375 107.0
TLS2_k127_144547_11 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000003838 108.0
TLS2_k127_144547_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 556.0
TLS2_k127_144547_3 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 430.0
TLS2_k127_144547_5 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 377.0
TLS2_k127_144547_6 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 354.0
TLS2_k127_144547_7 Nicotinamidase K08281 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000007272 250.0
TLS2_k127_144547_8 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000008375 214.0
TLS2_k127_144547_9 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000000000001029 125.0
TLS2_k127_1450340_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 6.059e-251 784.0
TLS2_k127_1450340_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 469.0
TLS2_k127_1450340_2 Dihydrodipicolinate reductase, C-terminus K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 430.0
TLS2_k127_1450340_3 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 303.0
TLS2_k127_1458345_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.218e-297 914.0
TLS2_k127_1458345_1 ATP synthase K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 461.0
TLS2_k127_1458345_2 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 399.0
TLS2_k127_1458345_3 regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 393.0
TLS2_k127_1458345_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 391.0
TLS2_k127_1458345_5 FCD K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 313.0
TLS2_k127_1458345_6 YfaZ precursor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006158 279.0
TLS2_k127_1458345_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000004125 230.0
TLS2_k127_1458345_8 ATP synthase alpha/beta chain, C terminal domain K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000001089 193.0
TLS2_k127_1466545_0 4Fe-4S dicluster domain K00184 - - 0.0 1343.0
TLS2_k127_1466545_1 Polysulphide reductase, NrfD K00185 - - 5.756e-223 697.0
TLS2_k127_1466545_2 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 450.0
TLS2_k127_1466545_3 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 374.0
TLS2_k127_1466545_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000023 243.0
TLS2_k127_1466545_5 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000001061 228.0
TLS2_k127_1467381_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 5.574e-264 822.0
TLS2_k127_1467381_1 extracellular solute-binding protein, family 1 K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 461.0
TLS2_k127_1467381_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 461.0
TLS2_k127_1467381_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 328.0
TLS2_k127_1467381_4 Thioredoxin domain - - - 0.000000000000000000000000000000000000002633 148.0
TLS2_k127_1467381_5 PilZ domain - - - 0.00000000000000000000000000002153 119.0
TLS2_k127_1467381_6 PilZ domain - - - 0.00000000000000000000000001915 115.0
TLS2_k127_1467381_7 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.00000000000003551 84.0
TLS2_k127_1467381_8 Involved in formation and maintenance of cell shape K03570 - - 0.00003364 46.0
TLS2_k127_1470611_0 Domains FehydlgC, FeS, sigma54 interaction, HTH8 - - - 0.0 1212.0
TLS2_k127_1470611_1 Bacterial periplasmic substrate-binding proteins K02030 - - 3.727e-278 864.0
TLS2_k127_1470611_2 response regulator - - - 2.749e-206 663.0
TLS2_k127_1470611_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 547.0
TLS2_k127_1470611_4 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 473.0
TLS2_k127_1470611_5 AAA domain K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 475.0
TLS2_k127_1470611_6 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 316.0
TLS2_k127_1470611_7 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008155 266.0
TLS2_k127_1516755_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 387.0
TLS2_k127_1516755_1 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 318.0
TLS2_k127_1516755_2 HAF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001056 275.0
TLS2_k127_1520158_0 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 516.0
TLS2_k127_1520158_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 520.0
TLS2_k127_1520158_2 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 377.0
TLS2_k127_1520158_3 RNA 2'-O ribose methyltransferase substrate binding K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 359.0
TLS2_k127_1520158_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000001842 101.0
TLS2_k127_1520158_5 - - - - 0.000000005262 59.0
TLS2_k127_1520158_6 - - - - 0.000000008745 57.0
TLS2_k127_1530956_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 9.247e-264 817.0
TLS2_k127_1530956_1 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 1.633e-225 700.0
TLS2_k127_1530956_2 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 4.327e-224 697.0
TLS2_k127_1550862_0 PFAM NAD dependent epimerase dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 359.0
TLS2_k127_1550862_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 353.0
TLS2_k127_1550862_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009495 290.0
TLS2_k127_1550862_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000001255 221.0
TLS2_k127_1550862_4 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000002464 210.0
TLS2_k127_1550862_5 - - - - 0.000000000000000000000000000000000000008143 156.0
TLS2_k127_1550862_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000001441 146.0
TLS2_k127_1558234_0 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 2.424e-293 909.0
TLS2_k127_1558234_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.783e-201 636.0
TLS2_k127_1558234_2 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 414.0
TLS2_k127_1558234_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 353.0
TLS2_k127_1558234_4 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 350.0
TLS2_k127_1558234_5 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 297.0
TLS2_k127_1558234_6 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000007576 234.0
TLS2_k127_1565806_0 Proposed homoserine kinase K15635 - 5.4.2.12 9.914e-204 640.0
TLS2_k127_1565806_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 575.0
TLS2_k127_1565806_2 integrase domain protein SAM domain protein K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 456.0
TLS2_k127_1565806_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 410.0
TLS2_k127_1565806_4 RNA methyltransferase K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 340.0
TLS2_k127_1565806_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003399 276.0
TLS2_k127_1565806_6 SpoU rRNA Methylase family K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000002402 133.0
TLS2_k127_1565806_7 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000000000001767 95.0
TLS2_k127_1565806_8 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000003605 63.0
TLS2_k127_158446_0 Sensor histidine kinase, HAMP domain-containing K07644 - 2.7.13.3 8.46e-203 641.0
TLS2_k127_158446_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 546.0
TLS2_k127_158446_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 541.0
TLS2_k127_158446_3 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 450.0
TLS2_k127_158446_4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 417.0
TLS2_k127_158446_5 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 411.0
TLS2_k127_158446_6 Sigma factor PP2C-like phosphatases K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000001225 210.0
TLS2_k127_158446_8 Kinase/pyrophosphorylase K09773 - 2.7.11.33,2.7.4.28 0.00000004211 54.0
TLS2_k127_1586785_0 Valyl tRNA synthetase tRNA binding arm K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1432.0
TLS2_k127_1586785_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000005482 132.0
TLS2_k127_1603267_0 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 1.002e-229 725.0
TLS2_k127_1603267_1 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 591.0
TLS2_k127_1603267_2 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 510.0
TLS2_k127_1603267_3 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 393.0
TLS2_k127_1603267_4 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 296.0
TLS2_k127_1603267_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000001042 139.0
TLS2_k127_1603267_7 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000000000000000207 91.0
TLS2_k127_1633092_0 Ftsk_gamma K03466 - - 0.0 1202.0
TLS2_k127_1633092_1 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 597.0
TLS2_k127_1633092_2 Competence-damaged protein K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 492.0
TLS2_k127_1633092_3 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 400.0
TLS2_k127_1633092_4 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 346.0
TLS2_k127_1633092_5 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000005043 249.0
TLS2_k127_1657316_0 Histidine kinase - - - 1.257e-285 883.0
TLS2_k127_1657316_1 response regulator - - - 2.46e-252 784.0
TLS2_k127_1657316_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 3.255e-206 653.0
TLS2_k127_1657316_3 Cytochrome c-type protein K15876 GO:0005575,GO:0006807,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 0.0000000000000000000000000000000000000000000000000000000000000001636 225.0
TLS2_k127_1657316_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000011 176.0
TLS2_k127_1682095_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 1.173e-200 635.0
TLS2_k127_1682095_1 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 609.0
TLS2_k127_1682095_10 response regulator, receiver K07315,K20977 - 3.1.3.3 0.000000000000000000000001418 117.0
TLS2_k127_1682095_11 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000437 76.0
TLS2_k127_1682095_13 phosphorelay signal transduction system - - - 0.00001242 49.0
TLS2_k127_1682095_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 491.0
TLS2_k127_1682095_3 S4 RNA-binding domain K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 466.0
TLS2_k127_1682095_4 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 439.0
TLS2_k127_1682095_5 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003248 275.0
TLS2_k127_1682095_6 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000002205 239.0
TLS2_k127_1682095_7 - - - - 0.00000000000000000000000000000000000000000004174 162.0
TLS2_k127_1682095_8 response regulator, receiver - - - 0.000000000000000000000000000000003867 143.0
TLS2_k127_1682095_9 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000003313 118.0
TLS2_k127_169535_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1218.0
TLS2_k127_169535_1 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 482.0
TLS2_k127_169535_2 (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000373 284.0
TLS2_k127_1707897_0 NUBPL iron-transfer P-loop NTPase - - - 1.466e-215 678.0
TLS2_k127_1707897_1 OB-fold nucleic acid binding domain K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 549.0
TLS2_k127_1707897_2 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 455.0
TLS2_k127_1707897_3 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 343.0
TLS2_k127_1707897_4 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 340.0
TLS2_k127_1707897_5 Transketolase, thiamine diphosphate binding domain K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 321.0
TLS2_k127_1707897_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000004397 86.0
TLS2_k127_1823596_0 Protein of unknown function (DUF512) - - - 3.401e-206 649.0
TLS2_k127_1823596_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 374.0
TLS2_k127_1823596_2 LrgB-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 334.0
TLS2_k127_1823596_3 LUD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009064 242.0
TLS2_k127_1823596_4 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000000000000016 207.0
TLS2_k127_1823596_5 LrgA family - - - 0.000000000000000000000000000000000000000000009277 166.0
TLS2_k127_185769_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 535.0
TLS2_k127_185769_1 HIGH Nucleotidyl Transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 516.0
TLS2_k127_185769_2 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 385.0
TLS2_k127_185769_3 Sugar fermentation stimulation protein K06206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 359.0
TLS2_k127_185769_4 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 329.0
TLS2_k127_185769_5 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 319.0
TLS2_k127_185769_6 Membrane K08988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 316.0
TLS2_k127_185769_7 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000000000000000000000003675 162.0
TLS2_k127_185769_8 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000001808 98.0
TLS2_k127_185769_9 Protein of unknown function (DUF2845) - - - 0.000000000000000000003204 97.0
TLS2_k127_1882197_0 GAD domain K01876 - 6.1.1.12 2.528e-236 736.0
TLS2_k127_1882197_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 6.868e-213 666.0
TLS2_k127_1882197_2 diguanylate cyclase - - - 1.253e-207 654.0
TLS2_k127_1882197_3 Domain of unknown function (DUF4131) K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 589.0
TLS2_k127_1897636_0 Predicted membrane protein (DUF2339) - - - 1.662e-219 705.0
TLS2_k127_1897636_1 E3 Ubiquitin ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 410.0
TLS2_k127_1897636_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002357 251.0
TLS2_k127_1897636_3 Belongs to the peptidase S8 family K13276 - - 0.0000000000000000000000000000000000000000000000000000001338 204.0
TLS2_k127_1897636_4 Uncharacterized ACR, COG1430 - - - 0.0000000000000000000000000003699 122.0
TLS2_k127_1933619_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.0 1132.0
TLS2_k127_1933619_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 9.286e-218 679.0
TLS2_k127_1933619_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 401.0
TLS2_k127_1933619_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 314.0
TLS2_k127_1933619_4 Rnf-Nqr subunit, membrane protein K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 310.0
TLS2_k127_1933619_5 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 292.0
TLS2_k127_1933619_6 FMN_bind K03612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 282.0
TLS2_k127_1933619_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002188 273.0
TLS2_k127_1944872_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 4.898e-318 980.0
TLS2_k127_1944872_1 Domain of unknown function (DUF2088) - - - 8.458e-226 704.0
TLS2_k127_1944872_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 327.0
TLS2_k127_1944872_3 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007426 224.0
TLS2_k127_1956981_0 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 537.0
TLS2_k127_1956981_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 529.0
TLS2_k127_1956981_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 367.0
TLS2_k127_1956981_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 291.0
TLS2_k127_1956981_4 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000001108 104.0
TLS2_k127_1956981_5 - - - - 0.00000000001472 70.0
TLS2_k127_1975560_0 Putative peptidoglycan binding domain K02450 - - 9.49e-220 693.0
TLS2_k127_1975560_1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 502.0
TLS2_k127_1975560_2 drug transmembrane transporter activity K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 418.0
TLS2_k127_1975560_3 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 363.0
TLS2_k127_1975560_4 domain, Protein K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005879 286.0
TLS2_k127_1975560_5 Type II secretion system protein B K02451 - - 0.00000000000000000000000000000000000000000000000000001949 197.0
TLS2_k127_1975560_6 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000000000000001638 182.0
TLS2_k127_1975560_7 - - - - 0.0000000000000000001766 91.0
TLS2_k127_1975560_8 Phospholipase_D-nuclease N-terminal - - - 0.0000000005847 61.0
TLS2_k127_2003556_0 response regulator K02481,K07714,K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 324.0
TLS2_k127_2003556_1 Integral membrane sensor signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 330.0
TLS2_k127_2003556_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000001027 237.0
TLS2_k127_2003556_3 Putative metal-binding motif - - - 0.0000000000002412 77.0
TLS2_k127_2015270_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 6.282e-271 842.0
TLS2_k127_2015270_1 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 9.781e-202 637.0
TLS2_k127_2015270_2 Radical SAM superfamily K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 584.0
TLS2_k127_2015270_3 Phosphorylase superfamily K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 438.0
TLS2_k127_2015270_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 303.0
TLS2_k127_2015270_5 NDK K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000007719 258.0
TLS2_k127_2015270_6 - - - - 0.000000000000000000000000000000000000000000000000000000286 209.0
TLS2_k127_2015270_7 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000000009457 119.0
TLS2_k127_2033206_0 Ferrous iron transport protein B C terminus K04759 - - 6.533e-246 766.0
TLS2_k127_2033206_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 430.0
TLS2_k127_2033206_2 Glutathione peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000009262 221.0
TLS2_k127_2033206_3 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000004705 205.0
TLS2_k127_2033206_4 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000003683 198.0
TLS2_k127_2033206_5 Domain of unknown function (DUF4442) K02614 - - 0.00000000000000000000000000000000007527 137.0
TLS2_k127_2037154_0 Sensor sigma-54-dependent transcriptional regulator, GAF and GAF domain-containing - - - 0.0 1493.0
TLS2_k127_2037154_1 prohibitin homologues K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002779 241.0
TLS2_k127_2045531_0 Sigma-54 interaction domain K02481 - - 5.1e-235 735.0
TLS2_k127_2045531_1 response regulator - - - 3.008e-219 689.0
TLS2_k127_2045531_2 histidine kinase, HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 561.0
TLS2_k127_2045531_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 482.0
TLS2_k127_2045531_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 476.0
TLS2_k127_2045531_5 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 379.0
TLS2_k127_2045531_6 cheY-homologous receiver domain K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000001532 226.0
TLS2_k127_2045531_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000356 197.0
TLS2_k127_2045531_8 - - - - 0.000000000000000000000000000000002753 138.0
TLS2_k127_2088919_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1186.0
TLS2_k127_2088919_1 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 586.0
TLS2_k127_2088919_2 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 400.0
TLS2_k127_2088919_3 Na+/H+ ion antiporter subunit K05562,K05569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002837 256.0
TLS2_k127_2088919_4 Uncharacterized BCR, YaiI/YqxD family COG1671 K09768 - - 0.000000000000000000000000000000000000000000000000000000000000000001211 233.0
TLS2_k127_2088919_5 Na+/H+ antiporter subunit K05571 - - 0.0000000000000000000000000000000000000000000004021 175.0
TLS2_k127_2088919_6 helix_turn_helix, Lux Regulon K02479 - - 0.00000000000000000000000000000000000000001118 158.0
TLS2_k127_2088919_7 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.000000000000000000000000000000637 124.0
TLS2_k127_2088919_8 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.000000000000000000000001814 105.0
TLS2_k127_2088919_9 Belongs to the peptidase M50B family - - - 0.000000000003986 70.0
TLS2_k127_2120324_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 3.216e-266 827.0
TLS2_k127_2120324_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 573.0
TLS2_k127_2120324_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009952 484.0
TLS2_k127_2165232_0 DHH family K07462 - - 1.744e-243 770.0
TLS2_k127_2165232_1 PFAM aminotransferase, class I and II K11358 - 2.6.1.1 1.293e-218 682.0
TLS2_k127_2165232_2 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 603.0
TLS2_k127_2165232_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 519.0
TLS2_k127_2165232_4 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 467.0
TLS2_k127_2165232_5 SecD/SecF GG Motif K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 445.0
TLS2_k127_2165232_6 Formate/nitrite transporter K06212,K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 394.0
TLS2_k127_2165232_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009776 262.0
TLS2_k127_2165232_8 Protein export membrane protein K03072 - - 0.0000000000000699 71.0
TLS2_k127_2193499_0 - - - - 1.853e-223 706.0
TLS2_k127_2193499_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 584.0
TLS2_k127_2193499_10 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000004339 66.0
TLS2_k127_2193499_2 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 576.0
TLS2_k127_2193499_3 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 394.0
TLS2_k127_2193499_4 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002286 281.0
TLS2_k127_2193499_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002286 253.0
TLS2_k127_2193499_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000002463 247.0
TLS2_k127_2193499_7 - - - - 0.000000000000000000000000000000000000003836 153.0
TLS2_k127_2193499_8 - - - - 0.00000000000000000000000000005466 117.0
TLS2_k127_2193499_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000008157 85.0
TLS2_k127_2207377_0 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0 1212.0
TLS2_k127_2207377_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 554.0
TLS2_k127_2207377_2 Prokaryotic glutathione synthetase, ATP-grasp domain K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 432.0
TLS2_k127_2207377_3 PFAM Succinylglutamate desuccinylase Aspartoacylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 415.0
TLS2_k127_2207377_4 Putative ATP-dependant zinc protease - - - 0.0000000000000000000000000000000000000000000000000000008252 197.0
TLS2_k127_2207377_5 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000000002962 120.0
TLS2_k127_2308428_0 TIGRFAM glutamate synthase (NADPH), homotetrameric - - - 4.297e-221 690.0
TLS2_k127_2308428_1 PFAM beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 601.0
TLS2_k127_2308428_2 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 287.0
TLS2_k127_2308428_3 protocatechuate 3,4-dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004286 233.0
TLS2_k127_2308428_4 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000005333 204.0
TLS2_k127_2308428_5 - - - - 0.00000000000000000000000000000000004331 146.0
TLS2_k127_2313248_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 7.164e-249 784.0
TLS2_k127_2313248_1 Cell cycle protein K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 594.0
TLS2_k127_2313248_2 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 578.0
TLS2_k127_2313248_3 rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 306.0
TLS2_k127_2313248_4 - K03571 - - 0.000000000000000000000000000000000000000000000000005788 188.0
TLS2_k127_2313248_5 CMP dCMP deaminase, zinc-binding - - - 0.000000000000000000000000000000000000000000000003934 177.0
TLS2_k127_2328498_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 546.0
TLS2_k127_2328498_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 335.0
TLS2_k127_2328498_10 Rhodanese-like domain - - - 0.0000000000000000000000000000001963 124.0
TLS2_k127_2328498_11 PQ loop repeat K15383 - - 0.00002929 49.0
TLS2_k127_2328498_2 Cobalamin-5-phosphate synthase K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 318.0
TLS2_k127_2328498_3 Ferrous iron transport protein B K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 321.0
TLS2_k127_2328498_4 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 316.0
TLS2_k127_2328498_5 Ferritin-like domain K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 288.0
TLS2_k127_2328498_6 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001488 269.0
TLS2_k127_2328498_7 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000001459 233.0
TLS2_k127_2328498_8 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000009197 225.0
TLS2_k127_2328498_9 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000599 180.0
TLS2_k127_2396630_0 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 4.789e-230 715.0
TLS2_k127_2396630_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 407.0
TLS2_k127_2396630_2 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 342.0
TLS2_k127_2396630_3 Ribosomal protein L11/L12 K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001866 254.0
TLS2_k127_2396630_4 Ribosomal protein L10 K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001572 231.0
TLS2_k127_2396630_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000025 199.0
TLS2_k127_2396630_6 Ribosomal protein L7/L12 dimerisation domain K02935 - - 0.0000000000000000000000000000000000000000000000000007076 185.0
TLS2_k127_2396630_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000002596 104.0
TLS2_k127_2396630_8 SecE/Sec61-gamma subunits of protein translocation complex K03073 - - 0.0000000000000000001416 91.0
TLS2_k127_2410602_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 597.0
TLS2_k127_2410602_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 432.0
TLS2_k127_2410602_10 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000007006 103.0
TLS2_k127_2410602_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 346.0
TLS2_k127_2410602_3 Bacterial DNA topoisomeraes I ATP-binding domain K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 316.0
TLS2_k127_2410602_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004025 239.0
TLS2_k127_2410602_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000007533 239.0
TLS2_k127_2410602_6 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000003094 194.0
TLS2_k127_2410602_7 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000004325 130.0
TLS2_k127_2410602_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000002673 131.0
TLS2_k127_2452108_0 CTP synthase N-terminus K01937 - 6.3.4.2 0.0 996.0
TLS2_k127_2452108_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 1.21e-239 747.0
TLS2_k127_2452108_2 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 536.0
TLS2_k127_2452108_3 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 474.0
TLS2_k127_2452108_4 PFAM ABC transporter related K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 395.0
TLS2_k127_2452108_5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000483 240.0
TLS2_k127_2452108_6 Lipopolysaccharide-assembly, LptC-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000004658 233.0
TLS2_k127_2452108_7 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000000001468 196.0
TLS2_k127_2453658_0 Phosphoribosylformylglycinamidine (FGAM) synthase K01952 - 6.3.5.3 3.943e-319 985.0
TLS2_k127_2453658_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 8.499e-253 782.0
TLS2_k127_2453658_2 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 377.0
TLS2_k127_2453658_3 Sensor histidine kinase, HAMP and PAS domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 312.0
TLS2_k127_2499867_0 Histidine kinase - - - 9.444e-263 829.0
TLS2_k127_2499867_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 7.356e-201 635.0
TLS2_k127_2499867_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 514.0
TLS2_k127_2499867_3 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.000000000000000000005482 97.0
TLS2_k127_250035_0 Bacterial regulatory protein, Fis family K02481 - - 1.216e-237 746.0
TLS2_k127_250035_1 Iron-containing alcohol dehydrogenase K00001 - 1.1.1.1 6.674e-205 644.0
TLS2_k127_250035_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 4.059e-200 630.0
TLS2_k127_250035_3 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 554.0
TLS2_k127_250035_4 Elongator protein 3, MiaB family, Radical SAM K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 412.0
TLS2_k127_250035_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 316.0
TLS2_k127_250035_6 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000000000000001214 172.0
TLS2_k127_250035_7 - - - - 0.0000000000000000000000000000000000000000009977 158.0
TLS2_k127_250035_8 - - - - 0.0000000000004594 71.0
TLS2_k127_2530311_0 Sodium:neurotransmitter symporter family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 548.0
TLS2_k127_2530311_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 490.0
TLS2_k127_2530311_2 OprF membrane domain K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 461.0
TLS2_k127_2530311_3 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 292.0
TLS2_k127_2530311_4 - - - - 0.000000000000000000000000000000000000000004092 158.0
TLS2_k127_2621154_0 UDP binding domain K02474,K13015 - 1.1.1.136 8.058e-216 677.0
TLS2_k127_2621154_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 505.0
TLS2_k127_2621154_2 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 381.0
TLS2_k127_2621154_3 Male sterility protein K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 346.0
TLS2_k127_2621154_4 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 299.0
TLS2_k127_2621154_5 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 299.0
TLS2_k127_2621154_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000005297 211.0
TLS2_k127_2621154_7 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000003678 158.0
TLS2_k127_2621154_8 RNA polymerase Rpb6 K03060 - 2.7.7.6 0.00000000000000000000000000001465 118.0
TLS2_k127_2629624_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.682e-280 872.0
TLS2_k127_2629624_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 441.0
TLS2_k127_2629624_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 386.0
TLS2_k127_2629624_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 320.0
TLS2_k127_2629624_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002825 269.0
TLS2_k127_2637117_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 3.914e-274 852.0
TLS2_k127_2637117_1 LacY proton/sugar symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 558.0
TLS2_k127_2637117_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 441.0
TLS2_k127_2637117_3 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 318.0
TLS2_k127_2637117_4 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.000000000000000000000000000000000003927 138.0
TLS2_k127_2637117_5 Pkd domain containing protein - - - 0.00000000000000000000002394 110.0
TLS2_k127_2637117_6 electron transfer activity K05337 - - 0.0000000000000000000008859 99.0
TLS2_k127_2637117_7 Bacterial regulatory protein, Fis family K07714 - - 0.000000000608 61.0
TLS2_k127_2719082_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.0 1017.0
TLS2_k127_2719082_1 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0 1014.0
TLS2_k127_2719082_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 541.0
TLS2_k127_284556_0 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009801 501.0
TLS2_k127_284556_1 Phosphorylase superfamily K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 463.0
TLS2_k127_284556_2 - - - - 0.0000000000000000000000000000000001019 138.0
TLS2_k127_2845957_0 - - - - 6.995e-297 921.0
TLS2_k127_2845957_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 1.974e-276 872.0
TLS2_k127_2845957_2 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 374.0
TLS2_k127_285779_0 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 2.197e-197 622.0
TLS2_k127_285779_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 398.0
TLS2_k127_285883_0 Elongator protein 3, MiaB family, Radical SAM - - - 2.834e-280 872.0
TLS2_k127_285883_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 7.589e-241 747.0
TLS2_k127_285883_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 7.525e-204 638.0
TLS2_k127_285883_3 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 526.0
TLS2_k127_285883_4 Redoxin K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 289.0
TLS2_k127_285883_5 Elongation factor SelB winged helix 3 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003142 240.0
TLS2_k127_285883_6 POTRA domain, FtsQ-type K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000021 236.0
TLS2_k127_2889409_0 MviN-like protein K03980 - - 3.603e-238 745.0
TLS2_k127_2889409_1 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 468.0
TLS2_k127_2889409_2 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 353.0
TLS2_k127_2889409_3 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 293.0
TLS2_k127_2889409_4 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000007481 264.0
TLS2_k127_2889409_5 Cytochrome c K16966,K17049,K17052 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000339 220.0
TLS2_k127_2889409_6 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000114 191.0
TLS2_k127_2889409_7 Ribosomal protein S20 K02968 - - 0.000000000000000000000000000000001716 132.0
TLS2_k127_2889409_8 Lipopolysaccharide-assembly - - - 0.0000003789 51.0
TLS2_k127_2898191_0 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 509.0
TLS2_k127_2898191_1 Domain of unknown function (DUF3473) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 499.0
TLS2_k127_2898191_2 AAA domain K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 405.0
TLS2_k127_2898191_3 AAA domain K08252 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 313.0
TLS2_k127_2898191_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006383 254.0
TLS2_k127_2898191_5 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000003143 205.0
TLS2_k127_2898191_6 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000001929 208.0
TLS2_k127_2967678_0 Heat shock 70 kDa protein K04043 - - 0.0 1034.0
TLS2_k127_2967678_1 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 571.0
TLS2_k127_2967678_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 469.0
TLS2_k127_2977881_0 TonB dependent receptor K02014 - - 3.004e-292 910.0
TLS2_k127_2977881_1 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 358.0
TLS2_k127_2977881_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 293.0
TLS2_k127_3005532_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0 1172.0
TLS2_k127_3005532_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 419.0
TLS2_k127_3005532_2 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 417.0
TLS2_k127_3005532_3 Sporulation and spore germination - - - 0.0000000000000000000000000000000000000000000000000000000005245 208.0
TLS2_k127_3019560_0 TRCF K03723 - - 0.0 1847.0
TLS2_k127_3019560_1 Quinolinate synthetase A protein K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 546.0
TLS2_k127_3019560_2 Sec-independent protein translocase protein (TatC) K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 429.0
TLS2_k127_3019560_3 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 381.0
TLS2_k127_3019560_4 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 327.0
TLS2_k127_3019560_5 mttA/Hcf106 family K03116,K03117 - - 0.00000000000000000000000000000692 122.0
TLS2_k127_3019560_6 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000009055 66.0
TLS2_k127_3028166_0 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 432.0
TLS2_k127_3028166_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 428.0
TLS2_k127_3028166_2 transport system permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 382.0
TLS2_k127_3028166_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 310.0
TLS2_k127_3028166_4 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000007736 204.0
TLS2_k127_3041330_0 RnfC Barrel sandwich hybrid domain K03615 - - 4.689e-240 749.0
TLS2_k127_3041330_1 NQR2, RnfD, RnfE family K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 537.0
TLS2_k127_3041330_2 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 512.0
TLS2_k127_3041330_3 4Fe-4S single cluster domain of Ferredoxin I K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 473.0
TLS2_k127_3041330_4 Rnf-Nqr subunit, membrane protein K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 331.0
TLS2_k127_3082139_0 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 549.0
TLS2_k127_3082139_1 PFAM tRNA synthetase, class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 457.0
TLS2_k127_3082139_2 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 417.0
TLS2_k127_3082139_3 Elongation factor P (EF-P) OB domain K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 334.0
TLS2_k127_3082139_5 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000009251 91.0
TLS2_k127_3082139_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000001046 68.0
TLS2_k127_3082139_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000048 55.0
TLS2_k127_3150636_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 546.0
TLS2_k127_3150636_1 Protein of unknown function (DUF3187) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 345.0
TLS2_k127_3150636_2 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000000009115 130.0
TLS2_k127_3165769_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 8.278e-233 726.0
TLS2_k127_3165769_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 540.0
TLS2_k127_3165769_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 480.0
TLS2_k127_3165769_3 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000005237 267.0
TLS2_k127_3165769_4 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000000000000008805 211.0
TLS2_k127_3165769_5 D-glycero-D-manno-heptose 7-phosphate biosynthetic process K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000008006 205.0
TLS2_k127_3165769_6 Uroporphyrinogen-III synthase HemD K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000001727 79.0
TLS2_k127_3165769_7 Protein of unknown function (DUF615) K09889 - - 0.0003718 44.0
TLS2_k127_3245517_0 Ultra-violet resistance protein B K03702 - - 0.0 1176.0
TLS2_k127_3245517_1 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 599.0
TLS2_k127_3262259_0 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 3e-267 825.0
TLS2_k127_3262259_1 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 589.0
TLS2_k127_3262259_10 - - - - 0.0000000000000000000000000000000000000000000003077 171.0
TLS2_k127_3262259_11 - - - - 0.00000000000000000000000000000000000000000159 166.0
TLS2_k127_3262259_12 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K13829 - 2.7.1.71,4.2.3.4 0.0001454 46.0
TLS2_k127_3262259_2 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 516.0
TLS2_k127_3262259_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 515.0
TLS2_k127_3262259_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 375.0
TLS2_k127_3262259_5 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 330.0
TLS2_k127_3262259_6 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000001162 233.0
TLS2_k127_3262259_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000002057 230.0
TLS2_k127_3262259_8 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000000000001616 215.0
TLS2_k127_3262259_9 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000003146 175.0
TLS2_k127_3297426_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.0 1378.0
TLS2_k127_3297426_1 AMP-binding enzyme K01897 - 6.2.1.3 2.977e-301 933.0
TLS2_k127_3297426_2 Thiolase, C-terminal domain K00632 - 2.3.1.16 2.596e-215 673.0
TLS2_k127_3297426_3 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 1.297e-199 625.0
TLS2_k127_3297426_4 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000003248 109.0
TLS2_k127_3320578_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 511.0
TLS2_k127_3320578_1 Peptidase dimerisation domain K13049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 479.0
TLS2_k127_3320578_2 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 449.0
TLS2_k127_3320578_3 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 379.0
TLS2_k127_3320578_4 Protein of unknown function, DUF480 K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 295.0
TLS2_k127_3320578_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003274 263.0
TLS2_k127_3320578_6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000000004248 208.0
TLS2_k127_3355450_0 RNA polymerases D K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 583.0
TLS2_k127_3355450_1 Ribosomal protein S4/S9 N-terminal domain K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 362.0
TLS2_k127_3355450_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 291.0
TLS2_k127_3355450_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002387 246.0
TLS2_k127_3355450_4 Ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000594 227.0
TLS2_k127_3355450_5 Ribosomal protein S13/S18 K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001278 205.0
TLS2_k127_3355450_6 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002067 201.0
TLS2_k127_3355450_7 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000009821 74.0
TLS2_k127_3376161_0 Molybdopterin oxidoreductase Fe4S4 domain K00370 - 1.7.5.1 0.0 2252.0
TLS2_k127_3376161_1 elongation factor Tu domain 2 protein K02355 - - 0.0 1247.0
TLS2_k127_3376161_10 Cytochrome c - - - 0.000000000000000000000000000000000000000164 156.0
TLS2_k127_3376161_11 PFAM Sporulation domain protein - - - 0.0000000000000000000000000000000003443 143.0
TLS2_k127_3376161_12 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.00000000000000004007 83.0
TLS2_k127_3376161_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 5.376e-234 734.0
TLS2_k127_3376161_3 Respiratory nitrate reductase beta C-terminal K00371,K17051 - 1.7.5.1 3.524e-207 647.0
TLS2_k127_3376161_4 HTH domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 458.0
TLS2_k127_3376161_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 443.0
TLS2_k127_3376161_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 391.0
TLS2_k127_3376161_7 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004562 272.0
TLS2_k127_3376161_8 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002127 268.0
TLS2_k127_3376161_9 PFAM MOSC domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001278 252.0
TLS2_k127_3452214_0 RecF/RecN/SMC N terminal domain K03631 - - 4.784e-234 737.0
TLS2_k127_3452214_1 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 555.0
TLS2_k127_3452214_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 450.0
TLS2_k127_3452214_3 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 365.0
TLS2_k127_3452214_4 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001292 250.0
TLS2_k127_3457392_0 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 432.0
TLS2_k127_3457392_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 341.0
TLS2_k127_3457392_2 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 301.0
TLS2_k127_3457392_3 GTP-binding GTPase Middle Region K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004144 267.0
TLS2_k127_3457392_4 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000003489 192.0
TLS2_k127_3457392_5 Peptidyl-prolyl cis-trans isomerase K01802,K03774 - 5.2.1.8 0.00000000000000000000000000000000000000000000000001777 183.0
TLS2_k127_349736_0 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 1.119e-257 804.0
TLS2_k127_349736_1 General secretory system II protein E domain protein - - - 1.381e-235 750.0
TLS2_k127_349736_10 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000031 140.0
TLS2_k127_349736_11 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000005965 120.0
TLS2_k127_349736_12 PFAM Rhodanese domain protein - - - 0.00000000000000000000000002672 116.0
TLS2_k127_349736_13 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000007603 96.0
TLS2_k127_349736_2 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 595.0
TLS2_k127_349736_3 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 461.0
TLS2_k127_349736_4 PFAM Cytochrome b b6 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 318.0
TLS2_k127_349736_5 ACT domain K03567 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 302.0
TLS2_k127_349736_6 Polypeptide deformylase K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000022 284.0
TLS2_k127_349736_7 electron transfer activity K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000334 256.0
TLS2_k127_349736_8 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008209 226.0
TLS2_k127_349736_9 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000001871 157.0
TLS2_k127_3558992_0 Carbon-nitrogen hydrolase K01950 - 6.3.5.1 8.378e-320 989.0
TLS2_k127_3558992_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 400.0
TLS2_k127_3558992_10 - - - - 0.000000000000000000000003928 104.0
TLS2_k127_3558992_2 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 377.0
TLS2_k127_3558992_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 287.0
TLS2_k127_3558992_4 SAM-dependent RNA methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006364 273.0
TLS2_k127_3558992_5 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000000000000000000000000000000000003922 203.0
TLS2_k127_3558992_6 Ribosomal protein L19 K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000197 198.0
TLS2_k127_3558992_7 RimM N-terminal domain K02860 - - 0.000000000000000000000000000000000000000000002984 173.0
TLS2_k127_3558992_8 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000000000000000003321 153.0
TLS2_k127_3558992_9 KH domain K06960 - - 0.000000000000000000000000000000000006106 138.0
TLS2_k127_3599051_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.366e-252 784.0
TLS2_k127_3599051_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 1.423e-237 741.0
TLS2_k127_3599051_10 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 295.0
TLS2_k127_3599051_11 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000004886 48.0
TLS2_k127_3599051_2 helicase superfamily c-terminal domain K03732 - 3.6.4.13 2.38e-220 690.0
TLS2_k127_3599051_3 Glycosyl transferase family, helical bundle domain K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 567.0
TLS2_k127_3599051_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 550.0
TLS2_k127_3599051_5 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 418.0
TLS2_k127_3599051_6 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 387.0
TLS2_k127_3599051_7 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 379.0
TLS2_k127_3599051_8 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 339.0
TLS2_k127_3599051_9 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 340.0
TLS2_k127_3643259_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 9.079e-274 845.0
TLS2_k127_3643259_1 PFAM biotin lipoyl attachment domain-containing protein - - - 4.517e-231 720.0
TLS2_k127_3643259_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 527.0
TLS2_k127_3643259_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 396.0
TLS2_k127_3643259_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 313.0
TLS2_k127_3643259_5 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 301.0
TLS2_k127_3643259_6 - - - - 0.000000000000000000004043 94.0
TLS2_k127_36717_0 Citrate lyase alpha subunit K01643 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.8.3.10 1.146e-257 801.0
TLS2_k127_36717_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 435.0
TLS2_k127_36717_10 - - - - 0.0000000000000000000000000000000001787 138.0
TLS2_k127_36717_11 Covalent carrier of the coenzyme of citrate lyase K01646 - - 0.0000000000000000000000000000001604 125.0
TLS2_k127_36717_12 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase K13927 GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046917,GO:0051186,GO:0051188,GO:0051189,GO:0051191,GO:0071704,GO:1901564,GO:1901576 2.4.2.52,2.7.7.61 0.000000000000374 76.0
TLS2_k127_36717_2 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase K01910 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008771,GO:0009987,GO:0016874,GO:0016877,GO:0016878,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 6.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 363.0
TLS2_k127_36717_3 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001609 286.0
TLS2_k127_36717_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001901 243.0
TLS2_k127_36717_5 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000000000000000000006719 240.0
TLS2_k127_36717_6 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000000000000000000000000000000000000000000002801 225.0
TLS2_k127_36717_8 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000006281 167.0
TLS2_k127_3705471_0 Elongator protein 3, MiaB family, Radical SAM K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 448.0
TLS2_k127_3705471_1 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 332.0
TLS2_k127_3705471_2 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002599 269.0
TLS2_k127_3705471_3 Belongs to the NifD NifK NifE NifN family K02587 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005992 243.0
TLS2_k127_3705471_4 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000001893 229.0
TLS2_k127_3705471_5 Dinitrogenase iron-molybdenum cofactor K02596 - - 0.00000000000000000000000000000000000000000000000000000000000007535 216.0
TLS2_k127_3705471_6 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000001334 182.0
TLS2_k127_3705471_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000001977 163.0
TLS2_k127_3795044_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 2.576e-219 692.0
TLS2_k127_3795044_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 2.01e-218 686.0
TLS2_k127_3795044_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 375.0
TLS2_k127_3795044_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004114 251.0
TLS2_k127_3795044_4 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000003917 185.0
TLS2_k127_3795044_5 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000000008447 174.0
TLS2_k127_3807689_0 DnaB-like helicase N terminal domain K02314 - 3.6.4.12 1.277e-260 807.0
TLS2_k127_3807689_1 Protein of unknown function (DUF933) K06942 - - 4.183e-203 638.0
TLS2_k127_3807689_2 Bacterial regulatory protein, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002058 256.0
TLS2_k127_3807689_3 Predicted membrane protein (DUF2232) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001698 258.0
TLS2_k127_3807689_4 Ribosomal protein L9, N-terminal domain K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000005416 210.0
TLS2_k127_3807689_5 Ribosomal protein S6 K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000003624 176.0
TLS2_k127_3807689_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000009912 147.0
TLS2_k127_3860891_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 549.0
TLS2_k127_3860891_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001369 214.0
TLS2_k127_3860891_2 - - - - 0.0000000000000000000000000000000000000000000000000001235 188.0
TLS2_k127_3860891_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000008059 171.0
TLS2_k127_3860891_4 - - - - 0.000000000000000000000000000000000000000000009899 164.0
TLS2_k127_3860891_5 - - - - 0.00000000000000000000000000000000000000000002928 162.0
TLS2_k127_3860891_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000008515 152.0
TLS2_k127_3860891_7 PFAM FeoA family protein K04758 - - 0.000000000000000000000000000000001712 137.0
TLS2_k127_3860891_8 PFAM FeoA family protein K04758 - - 0.000000000000000000002627 95.0
TLS2_k127_3864172_0 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 3.047e-224 703.0
TLS2_k127_3864172_1 PFAM Di-trans-poly-cis-decaprenylcistransferase-like K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 373.0
TLS2_k127_3864172_2 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 301.0
TLS2_k127_3864172_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009122 272.0
TLS2_k127_3864172_4 - - - - 0.0000000000000000000000000000000000000000000000003259 185.0
TLS2_k127_3876958_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1394.0
TLS2_k127_3876958_1 DNA Topoisomerase IV K02469 - 5.99.1.3 0.0 1359.0
TLS2_k127_3876958_10 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001133 275.0
TLS2_k127_3876958_11 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000176 263.0
TLS2_k127_3876958_12 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002525 263.0
TLS2_k127_3876958_13 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004877 261.0
TLS2_k127_3876958_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004955 248.0
TLS2_k127_3876958_15 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000005541 195.0
TLS2_k127_3876958_16 - - - - 0.000000000000000000000000000000000000000000009564 164.0
TLS2_k127_3876958_2 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0 1157.0
TLS2_k127_3876958_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.994e-240 751.0
TLS2_k127_3876958_4 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 1.182e-197 627.0
TLS2_k127_3876958_5 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 503.0
TLS2_k127_3876958_6 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 457.0
TLS2_k127_3876958_7 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 392.0
TLS2_k127_3876958_8 endonuclease III K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 316.0
TLS2_k127_3876958_9 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 286.0
TLS2_k127_3886169_0 ATPase domain of DNA mismatch repair MUTS family K07456 - - 0.0 1044.0
TLS2_k127_3886169_1 Sigma-70 factor, region 1.1 K03086 - - 6.92e-290 899.0
TLS2_k127_3886169_10 - - - - 0.0000001454 55.0
TLS2_k127_3886169_2 zinc finger K02316 - - 5.256e-254 796.0
TLS2_k127_3886169_3 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 536.0
TLS2_k127_3886169_4 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 403.0
TLS2_k127_3886169_5 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 275.0
TLS2_k127_3886169_6 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000000001274 216.0
TLS2_k127_3886169_7 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000009009 194.0
TLS2_k127_3886169_8 - - - - 0.0000000000000000000000000000000000001392 147.0
TLS2_k127_3886169_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000001104 112.0
TLS2_k127_3912808_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0 1087.0
TLS2_k127_3912808_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282,K18008 - 1.12.2.1,1.12.99.6 6.506e-218 680.0
TLS2_k127_3912808_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 501.0
TLS2_k127_3912808_3 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 306.0
TLS2_k127_3912808_4 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003361 247.0
TLS2_k127_3912808_5 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000002444 235.0
TLS2_k127_3912808_6 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000000007977 176.0
TLS2_k127_3954421_0 YceG-like family K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 415.0
TLS2_k127_3954421_1 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
TLS2_k127_3954421_2 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000001692 265.0
TLS2_k127_3954421_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000007547 226.0
TLS2_k127_3954421_4 - - - - 0.0000000000000000000000000000000000000000000000000002297 192.0
TLS2_k127_3954421_5 tRNA synthetases class I (K) K01870 - 6.1.1.5 0.00000000000000000000001447 99.0
TLS2_k127_4013625_0 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 604.0
TLS2_k127_4013625_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 561.0
TLS2_k127_4013625_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 346.0
TLS2_k127_4013625_3 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007707 271.0
TLS2_k127_4013625_4 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000001484 224.0
TLS2_k127_4013625_5 Belongs to the UPF0260 family K09160 - - 0.00000000000000000000000000000002242 131.0
TLS2_k127_4013625_6 NUDIX domain K03574 - 3.6.1.55 0.0000000000005062 70.0
TLS2_k127_4017268_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 3.849e-219 690.0
TLS2_k127_4017268_1 DnaJ molecular chaperone homology domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004597 273.0
TLS2_k127_4017268_2 Papain-like cysteine protease AvrRpt2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001131 242.0
TLS2_k127_4017268_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000007208 235.0
TLS2_k127_4017268_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000008484 214.0
TLS2_k127_4017268_5 - - - - 0.00000000000000000000000000000000000000000004711 164.0
TLS2_k127_4017268_6 - - - - 0.000000000000000000000000000000000000000009226 157.0
TLS2_k127_4027091_0 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 555.0
TLS2_k127_4027091_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 516.0
TLS2_k127_4027091_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 461.0
TLS2_k127_4027091_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007161 276.0
TLS2_k127_4027091_4 ATPases associated with a variety of cellular activities K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004738 253.0
TLS2_k127_4027091_5 Protein of unknown function (DUF454) K09790 - - 0.00000000000000000000000000000000000000000000449 170.0
TLS2_k127_4027091_6 - - - - 0.000000000000000000000000000000000000000006655 158.0
TLS2_k127_4027091_7 Domain of unknown function (DUF386) - - - 0.00000000000000000000000000000000000000001916 163.0
TLS2_k127_4027091_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000006258 87.0
TLS2_k127_4031777_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1395.0
TLS2_k127_4031777_1 AsmA-like C-terminal region - - - 9.02e-303 961.0
TLS2_k127_4031777_10 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000008414 95.0
TLS2_k127_4031777_11 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000004801 87.0
TLS2_k127_4031777_12 - K09892 - - 0.000000000001315 69.0
TLS2_k127_4031777_2 Domain of unknown function (DUF3552) K18682 - - 1.056e-267 831.0
TLS2_k127_4031777_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 448.0
TLS2_k127_4031777_4 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 434.0
TLS2_k127_4031777_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 411.0
TLS2_k127_4031777_6 RNA pseudouridylate synthase K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 330.0
TLS2_k127_4031777_7 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000003636 237.0
TLS2_k127_4031777_8 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000007598 195.0
TLS2_k127_4031777_9 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000004614 154.0
TLS2_k127_4033609_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly - - - 1.93e-292 905.0
TLS2_k127_4033609_1 Calcineurin-like phosphoesterase K03547 - - 1.843e-207 651.0
TLS2_k127_4033609_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 488.0
TLS2_k127_4033609_3 guanosine tetraphosphate metabolic process K07816 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 377.0
TLS2_k127_4033609_4 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 305.0
TLS2_k127_4033609_5 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 287.0
TLS2_k127_4033609_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000002935 134.0
TLS2_k127_4044944_0 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 467.0
TLS2_k127_4044944_1 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 337.0
TLS2_k127_4044944_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006882 274.0
TLS2_k127_4044944_3 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000000000000000000000000000005022 217.0
TLS2_k127_4044944_4 - - - - 0.00000000000000000000000000000000000000000000009584 174.0
TLS2_k127_4044944_5 Exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000245 168.0
TLS2_k127_4044944_6 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000004784 152.0
TLS2_k127_4044944_7 Uncharacterised protein family (UPF0270) K09898 - - 0.000000000000000000000000000001722 123.0
TLS2_k127_4049399_0 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 511.0
TLS2_k127_4049399_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 394.0
TLS2_k127_4049399_2 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 354.0
TLS2_k127_4049399_3 Ribosomal protein L3 K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 344.0
TLS2_k127_4049399_4 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004465 201.0
TLS2_k127_4049399_5 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000008167 193.0
TLS2_k127_4049399_6 Ribosomal protein S19 K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000001298 174.0
TLS2_k127_4049399_7 Ribosomal protein L23 K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000002601 159.0
TLS2_k127_4049399_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000002528 78.0
TLS2_k127_4067737_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.201e-215 682.0
TLS2_k127_4067737_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 546.0
TLS2_k127_4067737_2 Type II secretion system (T2SS), protein K - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001234 282.0
TLS2_k127_4067737_3 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000000001078 236.0
TLS2_k127_4067737_4 general secretion pathway protein - - - 0.00000000000000000000000000000000000000000000000000001556 195.0
TLS2_k127_4067737_5 GspL periplasmic domain - - - 0.000000000000000000000000000000000000001497 154.0
TLS2_k127_4067737_6 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000002702 144.0
TLS2_k127_4067737_7 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000000000000000000000000004226 146.0
TLS2_k127_4070291_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0 1240.0
TLS2_k127_4070291_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 449.0
TLS2_k127_4070291_2 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 391.0
TLS2_k127_4070291_3 Nucleoside recognition K06373 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 329.0
TLS2_k127_4070291_4 membrane protein required for spore maturation in B.subtilis K06374 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 291.0
TLS2_k127_4070291_5 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003569 277.0
TLS2_k127_4125190_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0 1174.0
TLS2_k127_4125190_1 Bacterial transcriptional repressor C-terminal K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000003719 229.0
TLS2_k127_4125190_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000008012 118.0
TLS2_k127_4125190_3 4Fe-4S binding domain - - - 0.00000000005325 70.0
TLS2_k127_4137583_0 GGDEF domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 457.0
TLS2_k127_4137583_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 411.0
TLS2_k127_4137583_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000001933 207.0
TLS2_k127_4143276_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 8.434e-320 983.0
TLS2_k127_4143276_1 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 1.832e-241 750.0
TLS2_k127_4143276_2 Glycoprotease family K01409,K14742 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 349.0
TLS2_k127_4143276_3 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005475 269.0
TLS2_k127_4143276_4 - K09794 - - 0.00000000000000000000007326 100.0
TLS2_k127_414933_0 Sodium:solute symporter family K14393 - - 4.66e-244 761.0
TLS2_k127_414933_1 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 9.008e-194 611.0
TLS2_k127_414933_10 SagB-type dehydrogenase domain - - - 0.000000000006623 65.0
TLS2_k127_414933_2 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 460.0
TLS2_k127_414933_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 351.0
TLS2_k127_414933_4 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 339.0
TLS2_k127_414933_5 Putative methyltransferase K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007269 279.0
TLS2_k127_414933_6 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009641 255.0
TLS2_k127_414933_7 Dephospho-CoA kinase K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000003183 250.0
TLS2_k127_414933_8 Domain of unknown function (DUF4212) - - - 0.0000000000000000000000000000000000003598 150.0
TLS2_k127_414933_9 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000001509 108.0
TLS2_k127_4149444_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 538.0
TLS2_k127_4149444_1 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 458.0
TLS2_k127_4149444_2 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 305.0
TLS2_k127_4149444_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009017 252.0
TLS2_k127_4149444_4 Tetraacyldisaccharide-1-P 4'-kinase K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000002276 229.0
TLS2_k127_4149444_5 PFAM Methyltransferase type - - - 0.0000000000000000000000000000000000000000000000000000000000000001807 234.0
TLS2_k127_4149444_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000004328 148.0
TLS2_k127_4149444_7 Trm112p-like protein K09791 - - 0.000000000000000000003245 94.0
TLS2_k127_4178225_0 UvrD-like helicase C-terminal domain K03656,K03657 - 3.6.4.12 1.453e-220 690.0
TLS2_k127_4178225_1 Radical_SAM C-terminal domain K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 512.0
TLS2_k127_4178225_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000003624 190.0
TLS2_k127_4191996_0 Hsp90 protein K04079 - - 1.592e-236 735.0
TLS2_k127_4191996_1 Region found in RelA / SpoT proteins - - - 6.494e-235 736.0
TLS2_k127_4191996_2 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009538 259.0
TLS2_k127_4191996_3 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000000000000000000000691 219.0
TLS2_k127_4191996_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000001092 151.0
TLS2_k127_4191996_5 - - - - 0.0000000000000000000000008618 104.0
TLS2_k127_4191996_6 AAA domain - - - 0.0009014 46.0
TLS2_k127_4193468_0 Glycosyltransferase 36 associated - - - 0.0 1475.0
TLS2_k127_4193468_1 Methyltransferase, chemotaxis proteins K13924 - 2.1.1.80,3.1.1.61 1.24e-225 708.0
TLS2_k127_4193468_2 PFAM sigma-54 factor interaction domain-containing protein K00575 - 2.1.1.80 1.314e-217 689.0
TLS2_k127_4193468_3 AI-2E family transporter - - - 0.000002543 54.0
TLS2_k127_423056_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 9.348e-310 972.0
TLS2_k127_423056_1 Cation transport protein K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 559.0
TLS2_k127_423056_2 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 305.0
TLS2_k127_4244515_0 Beta-eliminating lyase K04487 - 2.8.1.7 4.178e-208 653.0
TLS2_k127_4244515_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 607.0
TLS2_k127_4244515_2 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 381.0
TLS2_k127_4244515_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 290.0
TLS2_k127_4244515_4 Sporulation and spore germination - - - 0.000000000000000000000000000000000000000000000000001231 194.0
TLS2_k127_4244515_5 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000000000000000000000006726 162.0
TLS2_k127_4244515_6 - - - - 0.0000000000000000000000000000000000000009819 153.0
TLS2_k127_4276367_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 3.075e-234 735.0
TLS2_k127_4276367_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 9.499e-234 740.0
TLS2_k127_4276367_10 4Fe-4S binding domain - - - 0.0000000000000000000000002386 106.0
TLS2_k127_4276367_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000007058 97.0
TLS2_k127_4276367_12 zinc-ribbon domain - - - 0.0000000000000001198 94.0
TLS2_k127_4276367_2 Phosphate acetyl/butaryl transferase K00625,K13788 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 561.0
TLS2_k127_4276367_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 554.0
TLS2_k127_4276367_4 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001014 258.0
TLS2_k127_4276367_5 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000508 261.0
TLS2_k127_4276367_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000001603 234.0
TLS2_k127_4276367_7 Protein of unknown function (DUF1573) - - - 0.0000000000000000000000000000000000000000000000000000000000000002152 228.0
TLS2_k127_4276367_8 Glycine cleavage H-protein K02437 - - 0.000000000000000000000000000000000000000000000000000000002147 202.0
TLS2_k127_4276367_9 Prokaryotic glutathione synthetase, ATP-grasp domain K05844 - - 0.0000000000000000000000000000000003843 132.0
TLS2_k127_4300576_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1104.0
TLS2_k127_4300576_1 PFAM carboxyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 433.0
TLS2_k127_4300576_2 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001294 248.0
TLS2_k127_4331012_0 4Fe-4S dicluster domain - - - 0.0 1043.0
TLS2_k127_4331012_1 acyl-coa dehydrogenase - - - 1.743e-207 649.0
TLS2_k127_4331012_10 4Fe-4S binding domain - - - 0.00000000000000005406 82.0
TLS2_k127_4331012_2 PFAM Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 461.0
TLS2_k127_4331012_3 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 397.0
TLS2_k127_4331012_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 381.0
TLS2_k127_4331012_5 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 299.0
TLS2_k127_4331012_6 Elongation factor G C-terminus K06207 - - 0.0000000000000000000000000000000000000000000000000000001113 195.0
TLS2_k127_4331012_7 MerR, DNA binding K21902 - - 0.0000000000000000000000000000000000000000000000000001243 188.0
TLS2_k127_4331012_8 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000003291 145.0
TLS2_k127_4346533_0 Biotin carboxylase C-terminal domain K01958 - 6.4.1.1 0.0 1995.0
TLS2_k127_4346533_1 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 6.057e-308 952.0
TLS2_k127_4346533_2 prohibitin homologues - - - 0.0000000000000000000000000002665 115.0
TLS2_k127_4352759_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 445.0
TLS2_k127_4352759_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 353.0
TLS2_k127_4352759_2 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 356.0
TLS2_k127_4352759_3 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 351.0
TLS2_k127_4352759_4 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 286.0
TLS2_k127_4366460_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K05299 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.17.1.10 0.0 1285.0
TLS2_k127_4366460_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K15022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.17.1.10 0.0 1067.0
TLS2_k127_4366460_10 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000007659 243.0
TLS2_k127_4366460_11 - - - - 0.0000000000000000000000000000000000000000003916 161.0
TLS2_k127_4366460_12 Glutathione S-transferase, N-terminal domain K03676 - - 0.000000000000000000000000000000000000000909 149.0
TLS2_k127_4366460_13 COG3264 Small-conductance mechanosensitive channel K22051 - - 0.0000000000000000000000000000006772 130.0
TLS2_k127_4366460_14 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000001952 98.0
TLS2_k127_4366460_15 Transcriptional - - - 0.0000000000000044 82.0
TLS2_k127_4366460_16 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 0.0004311 48.0
TLS2_k127_4366460_2 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 536.0
TLS2_k127_4366460_3 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 517.0
TLS2_k127_4366460_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 435.0
TLS2_k127_4366460_5 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 391.0
TLS2_k127_4366460_6 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 393.0
TLS2_k127_4366460_7 PFAM transposase mutator type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 375.0
TLS2_k127_4366460_8 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003543 280.0
TLS2_k127_4366460_9 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002654 280.0
TLS2_k127_43701_0 FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 602.0
TLS2_k127_43701_1 histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 579.0
TLS2_k127_43701_2 Universal stress protein K06149 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002922 269.0
TLS2_k127_43701_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000002246 192.0
TLS2_k127_43701_4 Phosphorylase superfamily K03783 - 2.4.2.1 0.000000000000000000000000000000000000001792 149.0
TLS2_k127_4381725_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 3.515e-301 934.0
TLS2_k127_4381725_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 378.0
TLS2_k127_4381725_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 372.0
TLS2_k127_4381725_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003769 275.0
TLS2_k127_4381725_4 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005279 249.0
TLS2_k127_4381725_5 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0000000000001447 75.0
TLS2_k127_4419816_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 9.161e-230 716.0
TLS2_k127_4419816_1 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 1.737e-220 690.0
TLS2_k127_4419816_2 PCRF K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 538.0
TLS2_k127_4419816_3 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 413.0
TLS2_k127_4419816_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 366.0
TLS2_k127_4419816_5 Putative RNA methylase family UPF0020 K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 363.0
TLS2_k127_4419816_6 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 311.0
TLS2_k127_4419816_7 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000003077 207.0
TLS2_k127_4420103_0 Ammonium Transporter Family K03320 - - 1.183e-246 768.0
TLS2_k127_4420103_1 GAF domain - - - 8.068e-242 756.0
TLS2_k127_4420103_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 349.0
TLS2_k127_4420103_3 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000476 271.0
TLS2_k127_4420103_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000001309 227.0
TLS2_k127_4420103_5 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000000000000000000000001824 203.0
TLS2_k127_4427088_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 8.53e-283 891.0
TLS2_k127_4427088_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00334,K00335 - 1.6.5.3 1.846e-236 737.0
TLS2_k127_4427088_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 541.0
TLS2_k127_4427088_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005747 272.0
TLS2_k127_4427088_4 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.0000000000000000000009582 95.0
TLS2_k127_4433287_0 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 2.592e-295 914.0
TLS2_k127_4433287_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 563.0
TLS2_k127_4433287_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 392.0
TLS2_k127_4433287_3 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 337.0
TLS2_k127_4433287_4 PTS system sorbose-specific iic component K02795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000161 267.0
TLS2_k127_4433287_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003103 261.0
TLS2_k127_4433287_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000004416 242.0
TLS2_k127_4433287_7 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007052 242.0
TLS2_k127_4433287_8 PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.000000000000000000000000000000000000000000000000000000000000000001106 231.0
TLS2_k127_4433287_9 PTS system fructose IIA component K02793 - 2.7.1.191 0.00000000000000000000000000000000000000000000000000007837 188.0
TLS2_k127_4442240_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 577.0
TLS2_k127_4442240_1 PFAM Cytochrome bd ubiquinol oxidase, subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 407.0
TLS2_k127_4442240_2 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 361.0
TLS2_k127_4442240_3 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001171 245.0
TLS2_k127_4442240_4 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001998 240.0
TLS2_k127_4442240_5 Shikimate kinase K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000001727 227.0
TLS2_k127_4442240_6 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000002706 198.0
TLS2_k127_4442240_7 Domain of unknown function (DUF4492) - - - 0.0000000000000005129 80.0
TLS2_k127_4453880_0 AAA domain K03546 - - 1.655e-294 924.0
TLS2_k127_4453880_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 5.494e-284 879.0
TLS2_k127_4453880_2 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008386 610.0
TLS2_k127_4453880_3 CBS domain containing protein K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 465.0
TLS2_k127_4453880_4 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000005784 119.0
TLS2_k127_4453880_5 NapD protein K02570 - - 0.00000000000000000006474 93.0
TLS2_k127_4466457_0 ABC transporter transmembrane region K06147,K11085 - - 1.827e-274 853.0
TLS2_k127_4466457_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 561.0
TLS2_k127_4466457_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 553.0
TLS2_k127_4466457_3 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 346.0
TLS2_k127_4466457_4 Tetraacyldisaccharide-1-P 4'-kinase K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000009992 235.0
TLS2_k127_4499885_0 Domains REC, sigma54 interaction, HTH8 - - - 1.051e-259 804.0
TLS2_k127_4499885_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 3.146e-224 704.0
TLS2_k127_4499885_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 1.185e-196 621.0
TLS2_k127_4499885_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 546.0
TLS2_k127_4499885_4 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 509.0
TLS2_k127_4499885_5 Phosphorylase superfamily K00757,K01241 - 2.4.2.3,3.2.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 430.0
TLS2_k127_4499885_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 362.0
TLS2_k127_4499885_7 - - - - 0.000000000000000000000000000000000000000000006226 168.0
TLS2_k127_4499885_8 2 heme-binding sites K00428 - 1.11.1.5 0.0000000006801 60.0
TLS2_k127_4501969_0 Cytochrome c3 - - - 0.0 1033.0
TLS2_k127_4501969_1 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 5e-268 843.0
TLS2_k127_4501969_2 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 499.0
TLS2_k127_4501969_3 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003525 240.0
TLS2_k127_4558133_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1196.0
TLS2_k127_4558133_1 PFAM type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 608.0
TLS2_k127_4558133_2 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 594.0
TLS2_k127_4558133_3 Sensor histidine kinase, PAS and GAF domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 294.0
TLS2_k127_4558133_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000002969 189.0
TLS2_k127_4558133_5 RecX family K03565 - - 0.00000000000000000000000000000000000000000000000483 179.0
TLS2_k127_4581201_0 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 484.0
TLS2_k127_4581201_1 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 385.0
TLS2_k127_4581201_2 major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 312.0
TLS2_k127_4581201_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001494 183.0
TLS2_k127_4581201_4 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000002257 132.0
TLS2_k127_4643180_0 Multicopper oxidase K22350 - 1.16.3.3 0.0 1167.0
TLS2_k127_4643180_1 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 389.0
TLS2_k127_4643180_10 Protein involved in meta-pathway of phenol degradation - - - 0.0000001054 55.0
TLS2_k127_4643180_2 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001864 261.0
TLS2_k127_4643180_3 helix_turn_helix, Lux Regulon K02479 - - 0.00000000000000000000000000000000000000000000000000000000000000000001335 239.0
TLS2_k127_4643180_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000009865 239.0
TLS2_k127_4643180_5 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000159 216.0
TLS2_k127_4643180_6 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000159 200.0
TLS2_k127_4643180_7 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000000000000000000000000008842 143.0
TLS2_k127_4643180_8 Thioredoxin-like - - - 0.000000000000000000000000000001555 127.0
TLS2_k127_4643180_9 Multicopper oxidase K22350 - 1.16.3.3 0.00000000000005456 74.0
TLS2_k127_4697808_0 Bacterial regulatory protein, Fis family - - - 1.047e-239 749.0
TLS2_k127_4697808_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000007891 220.0
TLS2_k127_4697808_2 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000007544 189.0
TLS2_k127_470323_0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261,K00262 - 1.4.1.3,1.4.1.4 3.259e-274 847.0
TLS2_k127_470323_1 transcriptional regulator, XRE family - - - 0.00002534 52.0
TLS2_k127_4737265_0 Isocitrate dehydrogenase NADP-dependent, monomeric type K00031 - 1.1.1.42 0.0 1226.0
TLS2_k127_4737265_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 4.682e-212 662.0
TLS2_k127_4737265_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 563.0
TLS2_k127_4737265_3 GAD domain K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 542.0
TLS2_k127_4737265_4 PFAM thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 517.0
TLS2_k127_4737265_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 306.0
TLS2_k127_4737265_6 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000009806 217.0
TLS2_k127_4737265_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000000000000000004623 123.0
TLS2_k127_4750490_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.387e-245 766.0
TLS2_k127_4750490_1 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 1.013e-234 743.0
TLS2_k127_4750490_2 - - - - 0.000000000000000000000000000000001345 134.0
TLS2_k127_4750490_3 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000001654 64.0
TLS2_k127_4761356_0 Binding-protein-dependent transport system inner membrane component K02037 - - 1.868e-288 905.0
TLS2_k127_4761356_1 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 501.0
TLS2_k127_4761356_2 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 362.0
TLS2_k127_4763275_0 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 449.0
TLS2_k127_4763275_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 448.0
TLS2_k127_4763275_2 Aminotransferase, class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 403.0
TLS2_k127_4763275_3 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) K05951 - 2.4.2.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 395.0
TLS2_k127_4763275_4 ANTAR K22010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 303.0
TLS2_k127_4885483_0 PFAM ABC transporter related - - - 1.564e-214 670.0
TLS2_k127_4885483_1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 302.0
TLS2_k127_4885483_10 DNA primase activity K06919 - - 0.0000000000000001529 83.0
TLS2_k127_4885483_2 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001573 255.0
TLS2_k127_4885483_3 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000003597 206.0
TLS2_k127_4885483_4 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000000001593 210.0
TLS2_k127_4885483_5 PFAM AIG2 family protein - - - 0.0000000000000000000000000000000000000000000005666 169.0
TLS2_k127_4885483_6 Major facilitator superfamily K08224 - - 0.0000000000000000000000000000000000000000002616 163.0
TLS2_k127_4885483_7 - - - - 0.0000000000000000000000000000000000000000005382 164.0
TLS2_k127_4885483_9 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000000001907 104.0
TLS2_k127_4890233_0 PFAM Cys Met metabolism K01740 - 2.5.1.49 1.091e-204 644.0
TLS2_k127_4890233_1 COG2059 Chromate transport protein ChrA K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 529.0
TLS2_k127_4890233_2 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 456.0
TLS2_k127_4890233_3 Sodium:sulfate symporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 303.0
TLS2_k127_4890233_4 Thiamine-binding protein - - - 0.000000000000000000000000000000000004864 140.0
TLS2_k127_4890233_5 TIGRFAM thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000000000006846 100.0
TLS2_k127_4890233_6 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.0000000003071 61.0
TLS2_k127_4892619_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1285.0
TLS2_k127_4892619_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 572.0
TLS2_k127_4892619_2 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 554.0
TLS2_k127_4892619_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 301.0
TLS2_k127_4892619_4 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 301.0
TLS2_k127_4892619_5 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006012 267.0
TLS2_k127_4915362_0 AAA domain K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 543.0
TLS2_k127_4915362_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 454.0
TLS2_k127_4915362_2 - - - - 0.0000000000000000004339 92.0
TLS2_k127_4972764_0 Elongation factor SelB winged helix 3 K03833 - - 1.234e-306 946.0
TLS2_k127_4972764_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 5.493e-212 668.0
TLS2_k127_4972764_2 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001561 240.0
TLS2_k127_4972764_3 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000004726 84.0
TLS2_k127_4978319_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 5.95e-299 929.0
TLS2_k127_4978319_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 377.0
TLS2_k127_4978319_2 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000008516 100.0
TLS2_k127_5011345_0 Sulfatase - - - 0.0 1165.0
TLS2_k127_5011345_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001775 259.0
TLS2_k127_5011345_2 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000001312 238.0
TLS2_k127_5011345_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000004151 163.0
TLS2_k127_5011345_4 Potential Queuosine, Q, salvage protein family - - - 0.00001286 48.0
TLS2_k127_5013820_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.454e-252 780.0
TLS2_k127_5013820_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 454.0
TLS2_k127_5013820_2 Thymidylate synthase complementing protein K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 319.0
TLS2_k127_5013820_3 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 311.0
TLS2_k127_5013820_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000006654 165.0
TLS2_k127_5013820_5 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.000000000000000000000000002319 113.0
TLS2_k127_5025218_0 FtsH Extracellular K03798 - - 0.0 1086.0
TLS2_k127_5025218_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.185e-197 618.0
TLS2_k127_5025218_2 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 501.0
TLS2_k127_5025218_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 452.0
TLS2_k127_5025218_4 YbbR-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 324.0
TLS2_k127_5025218_5 TilS substrate binding domain K04075 - 6.3.4.19 0.00000000000000000000000000000001627 130.0
TLS2_k127_5052549_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 1.364e-257 807.0
TLS2_k127_5052549_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 4.717e-229 732.0
TLS2_k127_5052549_2 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 617.0
TLS2_k127_5052549_3 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 455.0
TLS2_k127_5052549_4 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000000003259 237.0
TLS2_k127_5052549_5 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000002613 175.0
TLS2_k127_5052549_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000002142 175.0
TLS2_k127_5052549_7 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000009415 151.0
TLS2_k127_5064084_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 4.353e-297 919.0
TLS2_k127_5064084_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 394.0
TLS2_k127_5064084_2 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 332.0
TLS2_k127_5064084_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 304.0
TLS2_k127_5064084_4 Methylamine utilisation protein MauE - - - 0.000000000000000000000000000000000000000000000000000005937 196.0
TLS2_k127_5064084_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000003385 194.0
TLS2_k127_5064084_6 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000000000000000000001086 141.0
TLS2_k127_5064084_7 SlyX K03745 - - 0.000000000000004878 79.0
TLS2_k127_5120436_0 Elongator protein 3, MiaB family, Radical SAM - - - 1.371e-249 774.0
TLS2_k127_5120436_1 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 2.638e-212 669.0
TLS2_k127_5120436_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 439.0
TLS2_k127_5120436_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 367.0
TLS2_k127_5120436_4 Acyl carrier protein phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002587 264.0
TLS2_k127_5120436_5 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002048 241.0
TLS2_k127_5183703_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1332.0
TLS2_k127_5183703_1 Domain of unknown function K03737 - 1.2.7.1 0.0 1051.0
TLS2_k127_5183703_2 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 381.0
TLS2_k127_5183703_3 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 293.0
TLS2_k127_5183703_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000006812 236.0
TLS2_k127_5188098_0 AMP-binding enzyme K01897 - 6.2.1.3 4.309e-262 817.0
TLS2_k127_5188098_1 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 611.0
TLS2_k127_5188098_2 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 489.0
TLS2_k127_5217296_0 AcrB/AcrD/AcrF family - - - 0.0 1509.0
TLS2_k127_5217296_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 485.0
TLS2_k127_5217296_2 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 398.0
TLS2_k127_5217296_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004118 271.0
TLS2_k127_5217296_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000004379 185.0
TLS2_k127_5219362_0 Bacterial DNA topoisomeraes I ATP-binding domain K03168 - 5.99.1.2 0.0 1015.0
TLS2_k127_5219362_1 Amidohydrolase family - - - 1.745e-208 651.0
TLS2_k127_5219362_10 Calcineurin-like phosphoesterase superfamily domain K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 347.0
TLS2_k127_5219362_11 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 343.0
TLS2_k127_5219362_12 polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001066 243.0
TLS2_k127_5219362_13 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000001204 228.0
TLS2_k127_5219362_14 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000000000000003541 196.0
TLS2_k127_5219362_15 Protein of unknown function (DUF494) K03747 - - 0.0000000000000000000000000000000000000000000000000002441 189.0
TLS2_k127_5219362_16 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000000000000006375 182.0
TLS2_k127_5219362_17 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000004703 128.0
TLS2_k127_5219362_2 PFAM peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 611.0
TLS2_k127_5219362_3 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 518.0
TLS2_k127_5219362_4 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 502.0
TLS2_k127_5219362_5 Chromate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 476.0
TLS2_k127_5219362_6 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 414.0
TLS2_k127_5219362_7 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 405.0
TLS2_k127_5219362_8 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 399.0
TLS2_k127_5219362_9 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 381.0
TLS2_k127_522447_0 in propionate K01720 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0047547,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0072329,GO:1901575 4.2.1.79 6.855e-232 728.0
TLS2_k127_522447_1 Sodium/hydrogen exchanger family - - - 1.48e-229 724.0
TLS2_k127_522447_11 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000003702 66.0
TLS2_k127_522447_2 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 1.676e-221 693.0
TLS2_k127_522447_3 Citrate synthase, C-terminal domain K01659 - 2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 483.0
TLS2_k127_522447_4 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 399.0
TLS2_k127_522447_5 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 321.0
TLS2_k127_522447_6 TonB C terminal K03646 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 293.0
TLS2_k127_522447_7 17 kDa outer membrane surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004011 275.0
TLS2_k127_522447_8 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000000000003231 224.0
TLS2_k127_522447_9 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000000000000000000000008162 197.0
TLS2_k127_5237753_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 1.961e-235 739.0
TLS2_k127_5237753_1 Histidine kinase K02482 - 2.7.13.3 8.738e-220 686.0
TLS2_k127_5237753_2 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.743e-217 678.0
TLS2_k127_5237753_3 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 447.0
TLS2_k127_5237753_4 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 437.0
TLS2_k127_5237753_5 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 439.0
TLS2_k127_5237753_6 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000492 222.0
TLS2_k127_5346417_0 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 593.0
TLS2_k127_5346417_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 539.0
TLS2_k127_5346417_11 Domain of unknown function (DUF1858) - - - 0.000000000000000000000000009198 112.0
TLS2_k127_5346417_12 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000000005643 96.0
TLS2_k127_5346417_13 - - - - 0.000001029 52.0
TLS2_k127_5346417_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 392.0
TLS2_k127_5346417_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 391.0
TLS2_k127_5346417_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 291.0
TLS2_k127_5346417_5 PFAM Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006846 269.0
TLS2_k127_5346417_6 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000005181 213.0
TLS2_k127_5346417_7 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000008478 185.0
TLS2_k127_5346417_8 CRS1_YhbY K07574 - - 0.000000000000000000000000000000000002394 143.0
TLS2_k127_5346417_9 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000001635 133.0
TLS2_k127_5356973_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1302.0
TLS2_k127_5356973_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 592.0
TLS2_k127_5356973_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 330.0
TLS2_k127_5356973_3 TAT (twin-arginine translocation) pathway signal sequence K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 321.0
TLS2_k127_5356973_4 Histidine kinase HAMP - - - 0.000000000000001667 87.0
TLS2_k127_5366038_0 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 470.0
TLS2_k127_5366038_1 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 450.0
TLS2_k127_5366038_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 354.0
TLS2_k127_5366038_3 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 293.0
TLS2_k127_5395984_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 4.701e-305 941.0
TLS2_k127_5395984_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 526.0
TLS2_k127_5395984_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 527.0
TLS2_k127_5395984_3 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 299.0
TLS2_k127_5395984_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001377 271.0
TLS2_k127_5410096_0 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 4.29e-321 999.0
TLS2_k127_5410096_1 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 476.0
TLS2_k127_5410096_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 439.0
TLS2_k127_5410096_3 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 357.0
TLS2_k127_5410096_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000001015 124.0
TLS2_k127_5410096_5 PEP-CTERM motif - - - 0.0000000000000000000000000003321 121.0
TLS2_k127_5423727_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1092.0
TLS2_k127_5423727_1 Glycosyltransferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 1.784e-244 764.0
TLS2_k127_5423727_10 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000003444 105.0
TLS2_k127_5423727_11 - - - - 0.00000005855 57.0
TLS2_k127_5423727_2 Lysine-2,3-aminomutase K01843 - 5.4.3.2 1.776e-237 739.0
TLS2_k127_5423727_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 3.088e-203 647.0
TLS2_k127_5423727_4 ThiF family K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 455.0
TLS2_k127_5423727_5 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 418.0
TLS2_k127_5423727_6 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 336.0
TLS2_k127_5423727_7 PFAM GCN5-related N-acetyltransferase K21935 - 2.3.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 313.0
TLS2_k127_5423727_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000007285 211.0
TLS2_k127_5423727_9 Dodecin K09165 - - 0.000000000000000000000000000002722 124.0
TLS2_k127_5440_0 PASTA domain K03587 - 3.4.16.4 1.512e-305 949.0
TLS2_k127_5440_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 6.987e-227 715.0
TLS2_k127_5440_2 Mur ligase middle domain K01925 - 6.3.2.9 1.413e-205 648.0
TLS2_k127_5440_3 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 1.847e-198 622.0
TLS2_k127_5440_4 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 5.776e-195 615.0
TLS2_k127_5440_5 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 591.0
TLS2_k127_5440_6 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 592.0
TLS2_k127_5440_7 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 557.0
TLS2_k127_5440_8 MraW methylase family K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 464.0
TLS2_k127_5440_9 Cell division protein FtsL - - - 0.0000000000000000000000000000000003387 134.0
TLS2_k127_5459117_0 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 471.0
TLS2_k127_5459117_1 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 425.0
TLS2_k127_5459117_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 425.0
TLS2_k127_5459117_3 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000047 221.0
TLS2_k127_553336_0 PFAM NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1467.0
TLS2_k127_553336_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 421.0
TLS2_k127_553336_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 391.0
TLS2_k127_553336_3 Ribosomal RNA adenine dimethylases K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 359.0
TLS2_k127_553336_4 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 289.0
TLS2_k127_553336_5 Pyridoxal-dependent decarboxylase conserved domain K01580 - 4.1.1.15 0.0000000000000000000000000000000000000000000000000000000000001755 216.0
TLS2_k127_553336_6 Lycopene cyclase protein K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.000000000000000000000000000000000000000000000000000000000003342 224.0
TLS2_k127_553336_7 - - - - 0.00000000000000000000000000003777 118.0
TLS2_k127_5542937_0 Polyribonucleotide nucleotidyltransferase, RNA binding domain K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1193.0
TLS2_k127_5542937_1 Translation-initiation factor 2 K02519 - - 0.0 1116.0
TLS2_k127_5542937_2 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 544.0
TLS2_k127_5542937_3 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 478.0
TLS2_k127_5542937_4 tRNA pseudouridylate synthase B C-terminal domain K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 400.0
TLS2_k127_5542937_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000005868 209.0
TLS2_k127_5542937_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000004692 174.0
TLS2_k127_5542937_7 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000004432 162.0
TLS2_k127_5542937_8 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000007239 126.0
TLS2_k127_5560159_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 7.872e-294 906.0
TLS2_k127_5560159_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 594.0
TLS2_k127_5560159_2 - - - - 0.0000000000000000000000004446 106.0
TLS2_k127_5560159_3 - - - - 0.0000005439 53.0
TLS2_k127_5576389_0 PFAM General secretory system II protein E domain protein K11740 - - 1.888e-266 842.0
TLS2_k127_5576389_1 Bacteriophage N adsorption protein A C-term - - - 0.000000002171 70.0
TLS2_k127_5576389_2 PilZ domain - - - 0.000009283 51.0
TLS2_k127_5608795_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 1.621e-311 974.0
TLS2_k127_5608795_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 394.0
TLS2_k127_5608795_2 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 390.0
TLS2_k127_5608795_3 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 376.0
TLS2_k127_5608795_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 305.0
TLS2_k127_5608795_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000006122 199.0
TLS2_k127_5608795_6 AAA domain - - - 0.00000000000000000000000000000000000000000000003007 179.0
TLS2_k127_5674184_0 Glutamine amidotransferases class-II K00764 - 2.4.2.14 6.744e-225 699.0
TLS2_k127_5674184_1 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 314.0
TLS2_k127_5674184_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004194 271.0
TLS2_k127_5674184_3 Chorismate mutase type II K04093 - 5.4.99.5 0.0000000000000000000000000000000000000007976 150.0
TLS2_k127_5674184_4 - - - - 0.00000000000000000000002182 102.0
TLS2_k127_5675761_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1279.0
TLS2_k127_5675761_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1011.0
TLS2_k127_5675761_10 Domain of unknown function (DUF1858) - - - 0.00000000000000000000007405 99.0
TLS2_k127_5675761_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.55e-275 859.0
TLS2_k127_5675761_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.644e-253 784.0
TLS2_k127_5675761_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.295e-232 725.0
TLS2_k127_5675761_5 Transcription elongation factor, N-terminal K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001235 266.0
TLS2_k127_5675761_6 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000007362 233.0
TLS2_k127_5675761_7 indolepyruvate ferredoxin oxidoreductase beta subunit K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000004488 205.0
TLS2_k127_5675761_9 Na+/Pi-cotransporter K03324 - - 0.00000000000000000000000005489 107.0
TLS2_k127_5694586_0 Glutamate synthase central domain K00265 - 1.4.1.13,1.4.1.14 1.649e-248 772.0
TLS2_k127_5694586_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 483.0
TLS2_k127_5694586_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 346.0
TLS2_k127_5694586_3 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 340.0
TLS2_k127_5694586_4 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000003247 175.0
TLS2_k127_5694586_5 Divergent 4Fe-4S mono-cluster K05337 - - 0.000000000000000000000000000000197 126.0
TLS2_k127_5694586_6 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000007119 115.0
TLS2_k127_5694586_7 Rubredoxin - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000001375 109.0
TLS2_k127_5703121_0 GXGXG motif - - - 0.0 1379.0
TLS2_k127_5703121_1 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1133.0
TLS2_k127_5703121_10 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000003547 170.0
TLS2_k127_5703121_11 Histidine phosphatase superfamily (branch 1) K08296 - - 0.000000000000148 73.0
TLS2_k127_5703121_2 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 6.145e-300 927.0
TLS2_k127_5703121_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 1.219e-233 740.0
TLS2_k127_5703121_4 Ammonium Transporter Family K03320 - - 4.458e-211 663.0
TLS2_k127_5703121_5 cheY-homologous receiver domain K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 338.0
TLS2_k127_5703121_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 301.0
TLS2_k127_5703121_7 CYTH K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003451 272.0
TLS2_k127_5703121_8 glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003527 268.0
TLS2_k127_5703121_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006585 246.0
TLS2_k127_5732257_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 590.0
TLS2_k127_5732257_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 427.0
TLS2_k127_5732257_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 428.0
TLS2_k127_5732257_3 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 432.0
TLS2_k127_5732257_4 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 319.0
TLS2_k127_5732257_5 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 264.0
TLS2_k127_5732257_6 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000003817 141.0
TLS2_k127_5777529_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.0 1013.0
TLS2_k127_5777529_1 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 6.557e-256 794.0
TLS2_k127_5777529_2 V-type ATPase 116kDa subunit family K02123 - - 1.314e-217 689.0
TLS2_k127_5777529_3 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 606.0
TLS2_k127_5777529_4 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 295.0
TLS2_k127_5777529_5 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000003785 216.0
TLS2_k127_5777529_6 ATP synthase subunit C K02124 - - 0.00000000000000000000000000000000000001009 149.0
TLS2_k127_5779464_0 ABC transporter K06158 - - 1.412e-316 974.0
TLS2_k127_5779464_1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K01586 - 4.1.1.20 7.924e-238 741.0
TLS2_k127_5779464_2 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 542.0
TLS2_k127_5779464_3 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 413.0
TLS2_k127_5779464_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000002407 180.0
TLS2_k127_5779464_5 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000001444 173.0
TLS2_k127_5779464_6 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000000000000000000000000000001036 173.0
TLS2_k127_5779464_7 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000000000000001443 163.0
TLS2_k127_5779464_8 Protein of unknown function (DUF2288) - - - 0.0000000000000000000000005885 107.0
TLS2_k127_5779464_9 flavin reductase domain protein - - - 0.00000000000007295 79.0
TLS2_k127_580563_0 Anticodon-binding domain of tRNA K01874 - 6.1.1.10 4.44e-299 925.0
TLS2_k127_580563_1 TatD related DNase K03424 - - 1.143e-238 745.0
TLS2_k127_580563_2 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 439.0
TLS2_k127_580563_3 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 337.0
TLS2_k127_580563_4 - - - - 0.0000000000000000000000000000000000000000000000000007328 195.0
TLS2_k127_580563_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000003667 90.0
TLS2_k127_580563_6 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000000000008327 85.0
TLS2_k127_580563_7 membrane - - - 0.0000000000000003261 79.0
TLS2_k127_5826848_0 Pilus formation protein N terminal region K02280 - - 1.839e-231 726.0
TLS2_k127_5826848_1 PFAM type II secretion system protein E K02283,K03609 - - 9.667e-216 675.0
TLS2_k127_5826848_2 Flp pilus polar localization response receiver ATPase TadZ, FlhG domain-containing K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 437.0
TLS2_k127_5826848_3 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 312.0
TLS2_k127_5826848_4 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000004279 153.0
TLS2_k127_5826848_5 PFAM TadE family protein - - - 0.000000000000000000000000000003857 124.0
TLS2_k127_5826848_6 - - - - 0.00000000000000000000000003367 109.0
TLS2_k127_5826848_7 Type IV leader peptidase family K02278 - 3.4.23.43 0.000000000118 62.0
TLS2_k127_5842168_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 577.0
TLS2_k127_5842168_1 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 375.0
TLS2_k127_5842168_2 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 374.0
TLS2_k127_5842168_3 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 338.0
TLS2_k127_5842168_4 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000003307 236.0
TLS2_k127_5842168_5 Dihydrofolate reductase K00287,K18589 - 1.5.1.3 0.0000000000000000000000000000000000000000000004908 170.0
TLS2_k127_5846408_0 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 512.0
TLS2_k127_5846408_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 436.0
TLS2_k127_5846408_2 ThiS-like ubiquitin K03148 - 2.7.7.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 417.0
TLS2_k127_5846408_3 Sodium:sulfate symporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 345.0
TLS2_k127_5846408_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
TLS2_k127_5846408_5 ThiS family K03154 - - 0.000000000000001105 79.0
TLS2_k127_5855513_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 480.0
TLS2_k127_5855513_1 General secretory system II protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001177 259.0
TLS2_k127_5855513_2 regulatory protein LysR - - - 0.000000000000000000000000007647 115.0
TLS2_k127_5866890_0 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 569.0
TLS2_k127_5866890_1 GTP1/OBG K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 562.0
TLS2_k127_5866890_2 Aldehyde dehydrogenase family K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 322.0
TLS2_k127_5866890_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000000000000000000000000002091 186.0
TLS2_k127_5866890_4 Ribonuclease E/G family K08301 - - 0.00000000000000000000000000000000000000000001796 162.0
TLS2_k127_5866890_5 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001824 150.0
TLS2_k127_5886798_0 DNA polymerase A domain K02335 - 2.7.7.7 1.436e-308 954.0
TLS2_k127_5886798_1 Bacterial type II/III secretion system short domain K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 312.0
TLS2_k127_5886798_2 Type II secretion system protein C K02452 - - 0.000000000000000000000000000000000000000000000000000000000000000000001089 246.0
TLS2_k127_5919123_0 Ferrous iron transport protein B K03977 - - 2.464e-204 645.0
TLS2_k127_5919123_1 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 562.0
TLS2_k127_5919123_2 KH domain K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 462.0
TLS2_k127_5919123_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000004643 193.0
TLS2_k127_5946550_0 DbpA RNA binding domain K05592 - 3.6.4.13 7.727e-278 865.0
TLS2_k127_5946550_1 RIO1 family K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 468.0
TLS2_k127_5946550_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000003469 185.0
TLS2_k127_5946550_3 Short C-terminal domain K08982 - - 0.00001178 51.0
TLS2_k127_5966316_0 PFAM sigma-54 factor interaction domain-containing protein - - - 1.004e-219 696.0
TLS2_k127_5966316_1 HipA-like C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 372.0
TLS2_k127_5966316_2 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000005194 240.0
TLS2_k127_5966316_3 CBS domain containing protein K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000001078 226.0
TLS2_k127_5966316_4 - - - - 0.00000000000000000000000000001433 121.0
TLS2_k127_6003531_0 E1-E2 ATPase K17686 - 3.6.3.54 1.076e-236 737.0
TLS2_k127_6003531_1 GGDEF domain containing protein - - - 6.918e-209 672.0
TLS2_k127_6096452_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1218.0
TLS2_k127_6096452_1 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 404.0
TLS2_k127_6096452_2 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000008509 237.0
TLS2_k127_6096452_3 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000006442 205.0
TLS2_k127_6096452_4 Anaerobic ribonucleoside-triphosphate reductase - - - 0.0000000000000000004338 87.0
TLS2_k127_611648_0 Collagenase K08303 - - 0.0 1147.0
TLS2_k127_611648_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 537.0
TLS2_k127_611648_2 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 384.0
TLS2_k127_61240_0 ATPases associated with a variety of cellular activities - - - 3.217e-215 678.0
TLS2_k127_61240_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 454.0
TLS2_k127_61240_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 398.0
TLS2_k127_6125240_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1269.0
TLS2_k127_6125240_1 POTRA domain TamA domain 1 K07277,K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 581.0
TLS2_k127_6147751_0 HD domain - - - 8.281e-282 881.0
TLS2_k127_6147751_1 Domain of unknown function (DUF3362) - - - 6.718e-260 816.0
TLS2_k127_6147751_2 Semialdehyde dehydrogenase, NAD binding domain K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 547.0
TLS2_k127_6147751_3 - - - - 0.0000000000000000000000000003467 115.0
TLS2_k127_6147751_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000001528 90.0
TLS2_k127_6173349_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.329e-276 854.0
TLS2_k127_6173349_1 His Kinase A (phosphoacceptor) domain - - - 2.668e-210 667.0
TLS2_k127_6173349_2 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001076 242.0
TLS2_k127_6173349_3 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000000000000000000000000000004554 214.0
TLS2_k127_6202866_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1611.0
TLS2_k127_6202866_1 GatB domain K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 2.055e-276 855.0
TLS2_k127_6202866_2 Initiation factor 2 subunit family K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 544.0
TLS2_k127_6202866_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 458.0
TLS2_k127_6202866_4 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 312.0
TLS2_k127_6202866_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 305.0
TLS2_k127_6202866_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 282.0
TLS2_k127_6202866_7 - - - - 0.000000000000004435 75.0
TLS2_k127_6202866_8 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000002293 52.0
TLS2_k127_6252364_0 PFAM ResB family protein K07399 - - 1.888e-221 695.0
TLS2_k127_6252364_1 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 492.0
TLS2_k127_6252364_2 PFAM methyltransferase K15460 - 2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 332.0
TLS2_k127_6252364_3 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000007077 85.0
TLS2_k127_6252364_4 Protein of unknown function (DUF721) - - - 0.0001479 46.0
TLS2_k127_626633_0 Uncharacterized protein family UPF0004 K14441 - 2.8.4.4 6.37e-234 729.0
TLS2_k127_626633_1 ABC transporter transmembrane region K06147,K18890 - - 1.579e-207 668.0
TLS2_k127_626633_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003579 256.0
TLS2_k127_626633_11 NusG domain II K00805 - 2.5.1.30 0.000000000000000472 83.0
TLS2_k127_626633_2 ABC transporter transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 602.0
TLS2_k127_626633_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 578.0
TLS2_k127_626633_4 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 560.0
TLS2_k127_626633_5 Hsp33 protein K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 387.0
TLS2_k127_626633_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 388.0
TLS2_k127_626633_7 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000385 271.0
TLS2_k127_626633_8 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006113 269.0
TLS2_k127_626633_9 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003948 264.0
TLS2_k127_6281729_0 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 461.0
TLS2_k127_6281729_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 432.0
TLS2_k127_6281729_10 Domain of unknown function (DUF4040) - - - 0.0000000000000000000000000000000005027 137.0
TLS2_k127_6281729_11 PFAM multiple resistance and pH regulation protein F K05570 - - 0.0000000000000000000000000000001068 129.0
TLS2_k127_6281729_12 CsbD-like - - - 0.000000000000000009756 84.0
TLS2_k127_6281729_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 431.0
TLS2_k127_6281729_3 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 313.0
TLS2_k127_6281729_4 PFAM Na H antiporter MnhB subunit-related protein K05566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002743 261.0
TLS2_k127_6281729_5 PFAM cation antiporter K05569 - - 0.0000000000000000000000000000000000000000000000000000000000000002822 224.0
TLS2_k127_6281729_6 NADH-ubiquinone oxidoreductase, chain 4L K05567 - - 0.0000000000000000000000000000000000000000000000000000000000000006895 220.0
TLS2_k127_6281729_7 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000003277 173.0
TLS2_k127_6281729_8 Na H antiporter - - - 0.00000000000000000000000000000000000000002046 154.0
TLS2_k127_6281729_9 PFAM Na H antiporter subunit K05571 - - 0.00000000000000000000000000000000000006923 144.0
TLS2_k127_6283699_0 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 364.0
TLS2_k127_6283699_1 PFAM Beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002013 282.0
TLS2_k127_6283699_2 TIGRFAM glutamate synthase (NADPH), homotetrameric - - - 0.00000000000000000000000000000000000000000000000000000000001901 208.0
TLS2_k127_6283699_3 - - - - 0.000000000000000000000000000000000000000000000000000000000116 206.0
TLS2_k127_6283699_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000759 165.0
TLS2_k127_6283699_6 PFAM S-layer K18650 - 3.2.1.82 0.000015 58.0
TLS2_k127_6295613_0 Domains REC, sigma54 interaction, HTH8 K02481 - - 6.29e-242 754.0
TLS2_k127_6295613_1 UbiA prenyltransferase family K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000009001 231.0
TLS2_k127_6295613_2 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000003372 190.0
TLS2_k127_6295613_3 domain protein - - - 0.0000000000000000000000000000000000000000000007411 177.0
TLS2_k127_6323081_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1279.0
TLS2_k127_6323081_1 LUD domain - - - 0.0 1244.0
TLS2_k127_6323081_2 CHAD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 557.0
TLS2_k127_6323081_3 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 554.0
TLS2_k127_6323081_4 TIGRFAM TRAP transporter solute receptor, TAXI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001979 264.0
TLS2_k127_632674_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 617.0
TLS2_k127_632674_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 436.0
TLS2_k127_632674_2 EXOIII - - - 0.000000000000000000000000000000000000000000000000000000000000005618 222.0
TLS2_k127_6330361_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 3.241e-305 953.0
TLS2_k127_6330361_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 3.188e-229 718.0
TLS2_k127_6330361_2 phosphoribosyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001479 253.0
TLS2_k127_6330361_3 COG1108 ABC-type Mn2 Zn2 transport systems permease components K09816 GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000001355 235.0
TLS2_k127_6330361_4 channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000001497 237.0
TLS2_k127_6330361_5 sirohydrochlorin cobaltochelatase activity K03794,K03795 - 4.99.1.3,4.99.1.4 0.000000000000000000000000000000001036 134.0
TLS2_k127_6392269_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1063.0
TLS2_k127_6392269_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 6.309e-301 933.0
TLS2_k127_6462293_0 amino acid-binding ACT domain protein K00003 - 1.1.1.3 1.995e-207 653.0
TLS2_k127_6462293_1 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 439.0
TLS2_k127_6462293_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000126 254.0
TLS2_k127_6462293_3 NusB family K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000005358 231.0
TLS2_k127_6462293_4 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000007416 193.0
TLS2_k127_6462293_5 Cytosol aminopeptidase family, N-terminal domain - - - 0.0000000000000000000000000000000000009155 149.0
TLS2_k127_6477957_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.674e-312 960.0
TLS2_k127_6477957_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly - - - 1.447e-268 843.0
TLS2_k127_6477957_2 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 458.0
TLS2_k127_6477957_3 Helix-hairpin-helix motif K02237 - - 0.0000000000000000000000000000000000000005166 154.0
TLS2_k127_6477957_4 - - - - 0.000000000000000000000000007475 109.0
TLS2_k127_6491604_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1005.0
TLS2_k127_6491604_1 Voltage gated chloride channel K03281 - - 6.409e-300 928.0
TLS2_k127_6491604_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 7.099e-202 633.0
TLS2_k127_6491604_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002099 241.0
TLS2_k127_6512876_0 FAD dependent oxidoreductase K07137 - - 1.159e-210 664.0
TLS2_k127_6512876_1 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 539.0
TLS2_k127_6512876_2 Domains REC, HisKA, HATPase_c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 510.0
TLS2_k127_6512876_3 PFAM penicillin-binding protein transpeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 486.0
TLS2_k127_6512876_4 Domains REC, HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 443.0
TLS2_k127_6512876_5 Isochorismatase family - - - 0.00000000000000000000000000000007553 124.0
TLS2_k127_6516946_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1583.0
TLS2_k127_6516946_1 HlyD family secretion protein K03585,K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 437.0
TLS2_k127_6516946_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000007452 224.0
TLS2_k127_659105_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 1.244e-284 882.0
TLS2_k127_659105_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 349.0
TLS2_k127_659105_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 332.0
TLS2_k127_659105_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002095 262.0
TLS2_k127_659105_4 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000001636 225.0
TLS2_k127_6596671_0 PFAM Amino acid - - - 7.014e-296 926.0
TLS2_k127_6596671_1 Sodium:neurotransmitter symporter family K03308 - - 2.361e-267 828.0
TLS2_k127_6596671_10 PFAM DNA polymerase, beta domain protein region K07075 - - 0.0000000000000000000000000000000000004446 143.0
TLS2_k127_6596671_11 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000005115 123.0
TLS2_k127_6596671_12 - - - - 0.00000000000000000000000008892 106.0
TLS2_k127_6596671_13 Biotin-requiring enzyme - - - 0.00000000000000000003524 96.0
TLS2_k127_6596671_14 Protein of unknown function DUF86 - - - 0.00000000000000000005697 91.0
TLS2_k127_6596671_15 Protein of unknown function DUF86 - - - 0.000000000000008676 75.0
TLS2_k127_6596671_2 Progressive ankylosis protein (ANKH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 589.0
TLS2_k127_6596671_3 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 575.0
TLS2_k127_6596671_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 444.0
TLS2_k127_6596671_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 348.0
TLS2_k127_6596671_6 PFAM SH3 type 3 K07184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 337.0
TLS2_k127_6596671_7 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009541 275.0
TLS2_k127_6596671_8 - - - - 0.000000000000000000000000000000000000000000001393 168.0
TLS2_k127_6603987_0 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000002026 246.0
TLS2_k127_6603987_1 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001767 237.0
TLS2_k127_6603987_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000003189 198.0
TLS2_k127_6603987_3 - - - - 0.0000000000000000000000000000000000000000000001644 174.0
TLS2_k127_6603987_4 - - - - 0.00000000000000000000000000000000000000000001331 165.0
TLS2_k127_6674061_0 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 1.176e-260 811.0
TLS2_k127_6674061_1 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.039e-233 726.0
TLS2_k127_6674061_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 606.0
TLS2_k127_6674061_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 349.0
TLS2_k127_6674061_4 NUDIX domain K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002254 274.0
TLS2_k127_6674061_5 RDD family - - - 0.000000000000000000000000000000000000000000004357 171.0
TLS2_k127_6678807_0 Belongs to the peptidase M16 family - - - 2.299e-245 763.0
TLS2_k127_6678807_1 Peptidase M16 inactive domain K07263 - - 3.1e-208 656.0
TLS2_k127_6678807_2 PFAM ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 382.0
TLS2_k127_6678807_3 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000001862 200.0
TLS2_k127_6678807_4 Bacterial protein of unknown function (DUF948) - - - 0.00000000000000000000000000000000001672 139.0
TLS2_k127_6678807_5 YtxH-like protein - - - 0.0000000000000000000000001207 109.0
TLS2_k127_6683091_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1904.0
TLS2_k127_6683091_1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 582.0
TLS2_k127_6683091_2 AAA domain K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 470.0
TLS2_k127_6683091_3 Lytic transglycolase K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 362.0
TLS2_k127_6683091_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004481 233.0
TLS2_k127_6706516_0 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 297.0
TLS2_k127_6706516_1 - - - - 0.0000000000000000005555 101.0
TLS2_k127_6706516_2 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000009663 79.0
TLS2_k127_6706516_3 - - - - 0.000000000000746 80.0
TLS2_k127_6723288_0 PFAM GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 497.0
TLS2_k127_6723288_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 392.0
TLS2_k127_6723288_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 340.0
TLS2_k127_6723288_3 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 320.0
TLS2_k127_6723288_4 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000001218 265.0
TLS2_k127_6723288_5 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000009817 242.0
TLS2_k127_6723288_6 ATP synthase I chain - - - 0.000000000000000000000000000000000000000105 154.0
TLS2_k127_6723288_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000000000000000000000000001633 128.0
TLS2_k127_6723288_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000357 82.0
TLS2_k127_6723288_9 - - - - 0.0000008227 55.0
TLS2_k127_6732131_0 PFAM Glycoside hydrolase family 65, central catalytic - - - 8.4e-322 998.0
TLS2_k127_6732131_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 398.0
TLS2_k127_6732131_2 Calcineurin-like phosphoesterase superfamily domain K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 348.0
TLS2_k127_6732131_3 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001462 258.0
TLS2_k127_6732131_4 PFAM ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000007445 207.0
TLS2_k127_6732131_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000000000000000000000000002456 192.0
TLS2_k127_6732131_6 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000000000003082 183.0
TLS2_k127_673301_0 Multicopper oxidase K22348 - 1.16.3.3 7.268e-200 637.0
TLS2_k127_673301_1 Domain of unknown function (DUF3524) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 502.0
TLS2_k127_673301_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 319.0
TLS2_k127_673301_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 309.0
TLS2_k127_673301_4 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000004804 184.0
TLS2_k127_673301_5 - - - - 0.0000000000000000000000000000000000000000000000003268 180.0
TLS2_k127_673301_6 - - - - 0.00000000000000000000000000000000000001293 153.0
TLS2_k127_6735051_0 DEAD_2 K10844 - 3.6.4.12 0.0 1371.0
TLS2_k127_6735051_1 Divalent cation transporter K06213 - - 1.088e-247 769.0
TLS2_k127_6735051_2 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 347.0
TLS2_k127_6744017_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1174.0
TLS2_k127_6744017_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 3.455e-217 681.0
TLS2_k127_6744017_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.302e-210 662.0
TLS2_k127_6744017_3 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 408.0
TLS2_k127_6744017_4 CRISPR-associated endoribonuclease Cas6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 313.0
TLS2_k127_6744017_5 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 292.0
TLS2_k127_6744017_6 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000000000000000000002458 157.0
TLS2_k127_6744017_7 - - - - 0.0000000000001028 74.0
TLS2_k127_6758051_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0 1405.0
TLS2_k127_6758051_1 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.467e-271 841.0
TLS2_k127_6758051_2 Ami_3 K01448 - 3.5.1.28 6.701e-205 652.0
TLS2_k127_6780789_0 DNA photolyase K01669 - 4.1.99.3 7.336e-201 638.0
TLS2_k127_6780789_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 486.0
TLS2_k127_6780789_2 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 484.0
TLS2_k127_6780789_3 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 472.0
TLS2_k127_6780789_4 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 305.0
TLS2_k127_6780789_5 intracellular protease K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000003383 227.0
TLS2_k127_6780789_6 Belongs to the Fur family K09825 - - 0.00000000000000000000000000000000000000000000000005866 183.0
TLS2_k127_6780789_7 response regulator - - - 0.000000000000000001408 87.0
TLS2_k127_6780789_8 Protein of unknown function (DUF1722) - - - 0.0000000000000006124 79.0
TLS2_k127_682500_0 Anthranilate synthase component I, N terminal region K01665 - 2.6.1.85 2.596e-211 664.0
TLS2_k127_682500_1 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002242 270.0
TLS2_k127_6838613_0 GIY-YIG type nucleases (URI domain) K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.459e-308 953.0
TLS2_k127_6838613_1 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 544.0
TLS2_k127_6838613_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 469.0
TLS2_k127_6838613_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006118 225.0
TLS2_k127_6866171_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 416.0
TLS2_k127_6866171_1 Sensor histidine kinase, HAMP domain-containing K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 358.0
TLS2_k127_6866171_2 Kinase/pyrophosphorylase K09773 - 2.7.11.33,2.7.4.28 0.0000000000008019 68.0
TLS2_k127_6892507_0 CBS domain containing protein K00974 - 2.7.7.72 0.0 1299.0
TLS2_k127_6892507_1 Dihydroorotate dehydrogenase K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 522.0
TLS2_k127_6892507_2 Oxidoreductase NAD-binding domain K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 494.0
TLS2_k127_6892507_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 332.0
TLS2_k127_6892507_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007692 275.0
TLS2_k127_6894722_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1174.0
TLS2_k127_6894722_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.551e-320 989.0
TLS2_k127_6894722_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 5.214e-297 918.0
TLS2_k127_6894722_3 NADH dehydrogenase K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 589.0
TLS2_k127_6894722_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 532.0
TLS2_k127_6894722_5 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 437.0
TLS2_k127_6894722_6 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003758 258.0
TLS2_k127_6894722_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000008577 224.0
TLS2_k127_6894722_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000001533 175.0
TLS2_k127_6927871_0 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1513.0
TLS2_k127_6927871_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 417.0
TLS2_k127_6927871_2 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000042 212.0
TLS2_k127_6927871_3 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000000000000000000000009535 170.0
TLS2_k127_6927871_4 Translation initiation factor 1A / IF-1 K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000006601 143.0
TLS2_k127_6939505_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.7.99.1 0.0 1020.0
TLS2_k127_6939505_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 473.0
TLS2_k127_6939505_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003471 266.0
TLS2_k127_6939505_3 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000002233 154.0
TLS2_k127_6973275_0 Ion channel - - - 1.09e-231 730.0
TLS2_k127_6973275_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 575.0
TLS2_k127_6973275_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 557.0
TLS2_k127_6973275_3 Domain of unknown function(DUF2779) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 421.0
TLS2_k127_6973275_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000009778 138.0
TLS2_k127_6973275_5 Domain of unknown function (DUF4911) - - - 0.000000000000000000000000002261 113.0
TLS2_k127_6973275_6 prohibitin homologues - - - 0.00000004085 55.0
TLS2_k127_6974351_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 7.301e-220 683.0
TLS2_k127_6974351_1 EXOIII - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 479.0
TLS2_k127_6974351_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 416.0
TLS2_k127_6974351_3 Rhomboid family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 381.0
TLS2_k127_6974351_4 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 367.0
TLS2_k127_6974351_5 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 349.0
TLS2_k127_6974351_6 Endonuclease V K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 339.0
TLS2_k127_6974351_7 Membrane protein, UPF0126 and UPF0126 domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 312.0
TLS2_k127_7014193_0 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 377.0
TLS2_k127_7014193_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000001249 134.0
TLS2_k127_7014193_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000002526 82.0
TLS2_k127_7014193_4 - - - - 0.000000001763 64.0
TLS2_k127_7014193_5 Belongs to the UPF0250 family K09158 - - 0.00000002264 59.0
TLS2_k127_7014193_7 PFAM peptidase M29, aminopeptidase II K19689 - - 0.0003314 43.0
TLS2_k127_7114914_0 Domain of unknown function K03737 - 1.2.7.1 0.0 1060.0
TLS2_k127_7114914_1 DNA polymerase III subunits gamma and tau domain III K02343 - 2.7.7.7 4.033e-257 805.0
TLS2_k127_7114914_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 3.103e-220 687.0
TLS2_k127_7114914_3 RecR protein K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 348.0
TLS2_k127_7114914_4 YbaB/EbfC DNA-binding family K09747 - - 0.000000000000000000000000000000000000000000000002737 175.0
TLS2_k127_7114914_5 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000005305 53.0
TLS2_k127_7133705_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1106.0
TLS2_k127_7133705_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 531.0
TLS2_k127_7133705_2 AIR synthase related protein, C-terminal domain K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 437.0
TLS2_k127_7133705_3 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 338.0
TLS2_k127_7133705_4 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000003329 138.0
TLS2_k127_7133705_5 Two component signalling adaptor domain - - - 0.0000000000000000000000000000003856 127.0
TLS2_k127_7136424_0 Carbon-nitrogen hydrolase K03820 - - 3.455e-219 689.0
TLS2_k127_7136424_1 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 466.0
TLS2_k127_7136424_2 PFAM CBS domain containing protein K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 448.0
TLS2_k127_7136424_3 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000004827 254.0
TLS2_k127_7136424_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000004281 111.0
TLS2_k127_7209846_0 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 7.793e-202 639.0
TLS2_k127_7209846_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 603.0
TLS2_k127_7209846_2 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 554.0
TLS2_k127_7209846_3 prohibitin homologues K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 520.0
TLS2_k127_7209846_4 prohibitin homologues K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 460.0
TLS2_k127_7209846_5 Predicted integral membrane protein (DUF2270) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 302.0
TLS2_k127_7254788_0 Peptidase M16C associated K06972 - - 9.44e-210 660.0
TLS2_k127_7254788_1 Peptidase M16C associated K06972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 470.0
TLS2_k127_7254788_2 Bacterial trigger factor protein (TF) C-terminus K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000003961 195.0
TLS2_k127_7254788_3 - - - - 0.0000000000000166 76.0
TLS2_k127_7273767_0 Amino-transferase class IV K00826 - 2.6.1.42 1.343e-199 625.0
TLS2_k127_7273767_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 454.0
TLS2_k127_7273767_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 361.0
TLS2_k127_7273767_3 SMART Chromosomal replication initiator DnaA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 339.0
TLS2_k127_7273767_4 DNA polymerase alpha chain like domain K02347,K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 301.0
TLS2_k127_7273767_5 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000418 121.0
TLS2_k127_7277809_0 GGDEF domain containing protein - - - 1.838e-201 658.0
TLS2_k127_7277809_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 321.0
TLS2_k127_7277809_2 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009925 318.0
TLS2_k127_7277809_3 GHKL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 305.0
TLS2_k127_7277809_4 response regulator, receiver K02485 - - 0.000000000000000000000000000000000000000000000000000004056 196.0
TLS2_k127_7277809_5 DoxX K15977 - - 0.0000000000000000000001528 97.0
TLS2_k127_7313359_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 479.0
TLS2_k127_7313359_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 432.0
TLS2_k127_7313359_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 335.0
TLS2_k127_7313359_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001492 268.0
TLS2_k127_7313359_4 D-Tyr-tRNA(Tyr) deacylase K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000003409 202.0
TLS2_k127_7313359_5 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000001463 182.0
TLS2_k127_7313359_6 Surface antigen - - - 0.00000000000000000000000000000000000001676 154.0
TLS2_k127_7313359_7 - - - - 0.0000000000000000000000000000000000000863 143.0
TLS2_k127_7313359_8 Protein of unknown function (DUF615) K09889 - - 0.0000000000000000000000000002232 118.0
TLS2_k127_7331887_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1020.0
TLS2_k127_7331887_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 4.435e-225 705.0
TLS2_k127_7331887_10 ThiS family - - - 0.000000000000000000000006983 107.0
TLS2_k127_7331887_2 PFAM iron-containing alcohol dehydrogenase K13954 - 1.1.1.1 2.469e-220 685.0
TLS2_k127_7331887_3 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 412.0
TLS2_k127_7331887_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 377.0
TLS2_k127_7331887_5 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 359.0
TLS2_k127_7331887_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 282.0
TLS2_k127_7331887_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001291 242.0
TLS2_k127_7331887_8 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000005676 183.0
TLS2_k127_7331887_9 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000000000000000000001407 177.0
TLS2_k127_7338126_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.599e-268 833.0
TLS2_k127_7338126_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 589.0
TLS2_k127_7338126_10 - - - - 0.00000000000000001172 82.0
TLS2_k127_7338126_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 541.0
TLS2_k127_7338126_3 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 417.0
TLS2_k127_7338126_4 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 289.0
TLS2_k127_7338126_5 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000002132 194.0
TLS2_k127_7338126_6 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000008935 154.0
TLS2_k127_7338126_7 DUF167 K09131 - - 0.000000000000000000000000000001951 122.0
TLS2_k127_7338126_8 YGGT family K02221 - - 0.000000000000000000000001481 108.0
TLS2_k127_7338126_9 - - - - 0.000000000000000000001242 98.0
TLS2_k127_742171_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 3.261e-244 760.0
TLS2_k127_742171_1 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 1.182e-222 696.0
TLS2_k127_742171_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 443.0
TLS2_k127_742171_3 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 430.0
TLS2_k127_742171_4 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 348.0
TLS2_k127_742171_5 MafB19-like deaminase K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000000000000000000000002816 252.0
TLS2_k127_742171_6 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000000000000000000000000009907 190.0
TLS2_k127_7433111_0 Molybdopterin oxidoreductase Fe4S4 domain K08352 - 1.8.5.5 0.0 1283.0
TLS2_k127_7433111_1 Protein of unknown function (DUF3373) - - - 8.425e-274 851.0
TLS2_k127_7433111_2 Cytochrome c bacterial - - - 4.363e-213 672.0
TLS2_k127_7433111_3 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000001623 222.0
TLS2_k127_7433111_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000004295 156.0
TLS2_k127_7433111_5 transcriptional regulator - - - 0.0000000000000000000000000000000000005819 144.0
TLS2_k127_767433_0 Protein of unknown function, DUF255 K06888 - - 1.383e-306 954.0
TLS2_k127_767433_1 DHHA2 K15986 - 3.6.1.1 9.696e-249 778.0
TLS2_k127_767433_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 303.0
TLS2_k127_767433_3 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000001651 214.0
TLS2_k127_767433_4 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000001778 205.0
TLS2_k127_794713_0 Class II release factor RF3, C-terminal domain K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 6.966e-290 897.0
TLS2_k127_794713_1 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 7.032e-249 774.0
TLS2_k127_794713_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 5.346e-242 762.0
TLS2_k127_794713_3 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 4.335e-202 634.0
TLS2_k127_794713_4 glycosyl transferase family 2 K21349 - 2.4.1.268 2.535e-196 621.0
TLS2_k127_794713_5 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000001676 209.0
TLS2_k127_794713_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000001714 192.0
TLS2_k127_794713_7 - - - - 0.0000000000000000000000000000000000000000426 154.0
TLS2_k127_824387_0 Cytochrome c - - - 2.174e-219 693.0
TLS2_k127_824387_1 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 478.0
TLS2_k127_824387_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 434.0
TLS2_k127_824387_4 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000003486 194.0
TLS2_k127_824387_5 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000005258 184.0
TLS2_k127_829116_0 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 3.713e-229 715.0
TLS2_k127_829116_1 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 413.0
TLS2_k127_829116_2 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 403.0
TLS2_k127_842388_0 L,D-transpeptidase catalytic domain K16291 - - 1.042e-205 650.0
TLS2_k127_842388_1 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 382.0
TLS2_k127_842388_2 Water Stress and Hypersensitive response - - - 0.0000000000000000000000000000000000000000000001834 173.0
TLS2_k127_842388_3 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000005019 126.0
TLS2_k127_842388_5 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000005474 111.0
TLS2_k127_842388_6 - - - - 0.00000000000000000106 92.0
TLS2_k127_842388_7 - - - - 0.00000000000000001369 85.0
TLS2_k127_842388_8 Transglycosylase SLT domain - - - 0.0000002698 61.0
TLS2_k127_924728_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 2.106e-250 778.0
TLS2_k127_924728_1 4Fe-4S dicluster domain - - - 1.101e-229 716.0
TLS2_k127_924728_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000008774 198.0
TLS2_k127_924728_3 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000001182 193.0
TLS2_k127_941749_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 8.147e-212 663.0
TLS2_k127_941749_1 PFAM Uncharacterised BCR, COG1649 K11931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 353.0
TLS2_k127_941749_2 MoaC family K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000005111 258.0
TLS2_k127_941749_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007597 223.0
TLS2_k127_941749_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000000000000000001519 204.0
TLS2_k127_941749_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. K10125 - 2.7.13.3 0.000000000000000000000000000000000000000000006472 172.0
TLS2_k127_978675_0 TRAM domain K06168 - 2.8.4.3 1.229e-231 722.0
TLS2_k127_978675_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 2.295e-227 708.0
TLS2_k127_978675_2 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 602.0
TLS2_k127_978675_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 562.0
TLS2_k127_978675_4 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 376.0
TLS2_k127_978675_5 - - - - 0.0000000000000000000000000000000000000000000000004462 182.0
TLS2_k127_978675_6 elongation factor Tu domain 2 protein K06207 - - 0.00000000000001639 74.0