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Overview

ID MAG04022
Name TLS2_bin.63
Sample SMP0104
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Actinomycetes
Order Actinomycetales
Family Kineosporiaceae
Genus DASTGO01
Species
Assembly information
Completeness (%) 92.31
Contamination (%) 2.6
GC content (%) 73.0
N50 (bp) 18,119
Genome size (bp) 5,103,785

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4132

Gene name Description KEGG GOs EC E-value Score Sequence
TLS2_k127_1032133_0 Highly conserved protein containing a thioredoxin domain K06888 - - 1.26e-249 792.0
TLS2_k127_1032133_1 ABC-2 family transporter protein K01421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 370.0
TLS2_k127_1032133_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000001465 184.0
TLS2_k127_1032133_3 - - - - 0.00000000000000000000000000006419 133.0
TLS2_k127_1032133_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000004013 94.0
TLS2_k127_1032133_5 - - - - 0.0000005519 57.0
TLS2_k127_1044027_0 protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 547.0
TLS2_k127_1044027_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 407.0
TLS2_k127_1044027_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 363.0
TLS2_k127_1044027_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002135 271.0
TLS2_k127_1044027_4 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000005601 206.0
TLS2_k127_1044027_6 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000008903 149.0
TLS2_k127_1047493_0 Domain of unknown function (DUF4419) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 503.0
TLS2_k127_1047493_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 364.0
TLS2_k127_1047493_10 - - - - 0.0000005596 56.0
TLS2_k127_1047493_11 - - - - 0.00001047 54.0
TLS2_k127_1047493_12 - - - - 0.0001225 49.0
TLS2_k127_1047493_13 Protein of unknown function (DUF3788) - - - 0.000191 50.0
TLS2_k127_1047493_2 Barstar (barnase inhibitor) - - - 0.0000000000000000000000000000000000000000000000000259 203.0
TLS2_k127_1047493_3 - - - - 0.0000000000000000000000000000000000000000000000001839 183.0
TLS2_k127_1047493_4 Zinc-dependent metalloprotease - - - 0.000000000000000000000000000000000000000006282 163.0
TLS2_k127_1047493_5 - - - - 0.0000000000000000000009399 108.0
TLS2_k127_1047493_6 lactoylglutathione lyase activity - - - 0.000000000000000000001072 98.0
TLS2_k127_1047493_7 lyase activity - - - 0.000000000000000000001516 111.0
TLS2_k127_1047493_8 trehalose-phosphatase activity - - - 0.00000000000000003053 93.0
TLS2_k127_1061918_0 ATPases associated with a variety of cellular activities K10548 - 3.6.3.17 1.02e-268 834.0
TLS2_k127_1061918_1 Branched-chain amino acid transport system / permease component K10547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 605.0
TLS2_k127_1061918_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 413.0
TLS2_k127_1061918_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 374.0
TLS2_k127_1061918_4 Amidohydrolase family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 370.0
TLS2_k127_1061918_5 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000003111 197.0
TLS2_k127_1061918_6 - - - - 0.0000000000000003663 81.0
TLS2_k127_1104972_0 Glutamine amidotransferase domain K00820 - 2.6.1.16 7.304e-270 842.0
TLS2_k127_1104972_1 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 595.0
TLS2_k127_1104972_10 hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005823 287.0
TLS2_k127_1104972_11 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000345 264.0
TLS2_k127_1104972_12 regulation of cellular protein catabolic process - GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000007047 239.0
TLS2_k127_1104972_13 Virulence activator alpha C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000005588 234.0
TLS2_k127_1104972_14 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000911 238.0
TLS2_k127_1104972_15 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000009738 215.0
TLS2_k127_1104972_16 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000007851 213.0
TLS2_k127_1104972_17 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000000000000000000000000001417 205.0
TLS2_k127_1104972_18 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000000000001119 210.0
TLS2_k127_1104972_19 DNA binding domain - - - 0.00000000000000000000000000000000000000000000000000001485 191.0
TLS2_k127_1104972_2 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 451.0
TLS2_k127_1104972_20 response regulator, receiver K03413 - - 0.000000000000000000000000000000000000000000000000007414 191.0
TLS2_k127_1104972_21 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000002811 196.0
TLS2_k127_1104972_22 response regulator, receiver K03413 - - 0.0000000000000000000000000000000000000000000000007115 181.0
TLS2_k127_1104972_23 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000008345 186.0
TLS2_k127_1104972_25 - - - - 0.0000000000000000000000000009371 117.0
TLS2_k127_1104972_26 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000003168 96.0
TLS2_k127_1104972_27 DNA-binding transcription factor activity K13280 - 3.4.21.89 0.000000000000000002231 96.0
TLS2_k127_1104972_28 - - - - 0.0000000000000009014 84.0
TLS2_k127_1104972_29 - - - - 0.00000000002139 72.0
TLS2_k127_1104972_3 cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 445.0
TLS2_k127_1104972_30 Bifunctional DNA primase/polymerase, N-terminal - - - 0.00000000002682 76.0
TLS2_k127_1104972_31 - - - - 0.00000000005497 75.0
TLS2_k127_1104972_32 - - - - 0.000002102 60.0
TLS2_k127_1104972_33 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00003771 48.0
TLS2_k127_1104972_4 (EAL) domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 431.0
TLS2_k127_1104972_5 PFAM MCP methyltransferase, CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 393.0
TLS2_k127_1104972_6 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 344.0
TLS2_k127_1104972_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 347.0
TLS2_k127_1104972_8 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 334.0
TLS2_k127_1104972_9 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 336.0
TLS2_k127_1107058_0 Peptidase s1 and s6 chymotrypsin hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 398.0
TLS2_k127_1107058_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 392.0
TLS2_k127_1107058_10 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000294 115.0
TLS2_k127_1107058_11 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.0000000000000000000005008 95.0
TLS2_k127_1107058_12 Transposase - - - 0.0000000000000000000005461 102.0
TLS2_k127_1107058_13 epimerase dehydratase - - - 0.0000000000000000002417 89.0
TLS2_k127_1107058_14 transposase activity - - - 0.000000000000001703 84.0
TLS2_k127_1107058_15 - - - - 0.00000000002252 73.0
TLS2_k127_1107058_16 Transposase - - - 0.000000001775 61.0
TLS2_k127_1107058_18 Domain of unknown function (DUF4419) - - - 0.0000001068 60.0
TLS2_k127_1107058_19 - - - - 0.0000001258 59.0
TLS2_k127_1107058_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 368.0
TLS2_k127_1107058_20 helicase - - - 0.0000001901 54.0
TLS2_k127_1107058_21 epimerase dehydratase - - - 0.0000003471 57.0
TLS2_k127_1107058_22 trans-aconitate 2-methyltransferase activity K02169,K03810,K09915 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.1.1.197 0.000001149 50.0
TLS2_k127_1107058_23 PFAM transposase mutator type - - - 0.000002465 49.0
TLS2_k127_1107058_24 Domain of unknown function (DUF4419) - - - 0.0009203 49.0
TLS2_k127_1107058_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 325.0
TLS2_k127_1107058_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001656 237.0
TLS2_k127_1107058_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000002376 243.0
TLS2_k127_1107058_6 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000251 216.0
TLS2_k127_1107058_7 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000006027 158.0
TLS2_k127_1107058_8 - - - - 0.0000000000000000000000000000000000000001133 159.0
TLS2_k127_1107058_9 Diguanylate cyclase - - - 0.00000000000000000000000000000007259 142.0
TLS2_k127_115242_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 599.0
TLS2_k127_115242_1 transcriptional regulator, TetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 393.0
TLS2_k127_115242_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 366.0
TLS2_k127_115242_3 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 310.0
TLS2_k127_115242_4 - - - - 0.00000000000000000000001356 106.0
TLS2_k127_115242_5 - - - - 0.00000000000000006784 86.0
TLS2_k127_115242_6 - - - - 0.0000000000001015 76.0
TLS2_k127_115242_7 - - - - 0.0004003 48.0
TLS2_k127_116498_0 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 4.176e-196 654.0
TLS2_k127_116498_1 Peptidase dimerisation domain K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 489.0
TLS2_k127_116498_2 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 435.0
TLS2_k127_116498_3 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 384.0
TLS2_k127_116498_4 Belongs to the LOG family K06966 GO:0003674,GO:0003824,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009690,GO:0009691,GO:0009987,GO:0010817,GO:0016787,GO:0016798,GO:0016799,GO:0034754,GO:0042445,GO:0042446,GO:0044237,GO:0044249,GO:0046483,GO:0065007,GO:0065008,GO:0071704,GO:1901564 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000001777 232.0
TLS2_k127_116498_5 - - - - 0.0000000592 63.0
TLS2_k127_116498_6 - - - - 0.000002823 52.0
TLS2_k127_1184668_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 457.0
TLS2_k127_1184668_1 Phosphoserine phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 340.0
TLS2_k127_1184668_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000002339 217.0
TLS2_k127_1184668_3 Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000001449 156.0
TLS2_k127_1184668_4 Protein of unknown function (DUF2871) - - - 0.00000000000000000000000000000000000000002386 157.0
TLS2_k127_1184668_5 - - - - 0.000000000000000000000000000000000999 133.0
TLS2_k127_1184668_6 DNA-binding transcription factor activity K06075 - - 0.0000000000000000000000000004691 119.0
TLS2_k127_1184668_7 pyridoxamine 5-phosphate K07005 - - 0.000000002245 66.0
TLS2_k127_1184668_8 D-alanine [D-alanyl carrier protein] ligase activity K16428,K16429 - - 0.000000004828 69.0
TLS2_k127_1198770_0 Long-chain fatty acid--CoA ligase K01897 - 6.2.1.3 3.194e-250 785.0
TLS2_k127_1198770_1 Belongs to the class-II DAHP synthase family K01626,K16019 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.5.1.54 4.788e-237 739.0
TLS2_k127_1198770_10 Type ii secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 355.0
TLS2_k127_1198770_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 341.0
TLS2_k127_1198770_12 Two component transcriptional regulator, luxr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 330.0
TLS2_k127_1198770_13 Type ii secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 342.0
TLS2_k127_1198770_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 340.0
TLS2_k127_1198770_15 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 337.0
TLS2_k127_1198770_16 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 321.0
TLS2_k127_1198770_17 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 308.0
TLS2_k127_1198770_18 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 308.0
TLS2_k127_1198770_19 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001047 279.0
TLS2_k127_1198770_2 Type ii secretion system protein e K02283 - - 2.519e-213 670.0
TLS2_k127_1198770_20 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000414 207.0
TLS2_k127_1198770_21 - - - - 0.00000000000000000000000000000000000000000002644 187.0
TLS2_k127_1198770_22 HNH endonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000542 156.0
TLS2_k127_1198770_23 endonuclease exonuclease phosphatase - - - 0.000000000000000000000000000000000009867 149.0
TLS2_k127_1198770_24 - - - - 0.0000000000000001188 92.0
TLS2_k127_1198770_25 Transposase IS116/IS110/IS902 family - - - 0.0000000009504 64.0
TLS2_k127_1198770_26 - - - - 0.0000003311 63.0
TLS2_k127_1198770_3 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 521.0
TLS2_k127_1198770_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 479.0
TLS2_k127_1198770_5 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 446.0
TLS2_k127_1198770_6 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 392.0
TLS2_k127_1198770_7 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 377.0
TLS2_k127_1198770_8 Evidence 2b Function of strongly homologous gene K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 386.0
TLS2_k127_1198770_9 ROK family K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 374.0
TLS2_k127_1212357_0 ATPase involved in DNA repair - - - 0.0 1160.0
TLS2_k127_1212357_1 the major facilitator superfamily - - - 7.948e-227 726.0
TLS2_k127_1212357_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 599.0
TLS2_k127_1212357_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 367.0
TLS2_k127_1212357_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 372.0
TLS2_k127_1212357_5 Sortase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004009 235.0
TLS2_k127_1212357_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate - - - 0.000000000000000000000000000000000000000000004719 167.0
TLS2_k127_1212357_7 MT0933-like antitoxin protein - - - 0.0000002489 60.0
TLS2_k127_1212357_8 MT0933-like antitoxin protein - - - 0.0000008941 59.0
TLS2_k127_1244952_0 amidohydrolase - - - 5.206e-202 644.0
TLS2_k127_1244952_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 606.0
TLS2_k127_1244952_10 - K14337,K14339 - - 0.0000000000001051 76.0
TLS2_k127_1244952_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 491.0
TLS2_k127_1244952_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 387.0
TLS2_k127_1244952_4 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 378.0
TLS2_k127_1244952_5 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 313.0
TLS2_k127_1244952_6 SpoIID LytB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001173 292.0
TLS2_k127_1244952_7 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003661 273.0
TLS2_k127_1244952_8 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000001562 218.0
TLS2_k127_1244952_9 Protein of unknown function (DUF454) K09790 - - 0.0000000000000000000001145 109.0
TLS2_k127_1274468_0 Hydantoinase K01474 - 3.5.2.14 0.0 1064.0
TLS2_k127_1274468_1 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 542.0
TLS2_k127_1274468_2 - - - - 0.00000002345 64.0
TLS2_k127_1274468_3 - - - - 0.00006187 52.0
TLS2_k127_1280190_0 Tellurium resistance protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 593.0
TLS2_k127_1280190_1 DNA-binding transcriptional activator of the SARP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 383.0
TLS2_k127_1280190_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001461 244.0
TLS2_k127_1280190_3 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.00004567 47.0
TLS2_k127_1280190_4 - - - - 0.00006916 51.0
TLS2_k127_1289601_0 ABC transporter K06147 - - 2.606e-274 858.0
TLS2_k127_1289601_1 ABC transporter K06158 - - 5.977e-268 841.0
TLS2_k127_1289601_10 - - - - 0.00000000000000000000001569 105.0
TLS2_k127_1289601_11 Protein of unknown function (DUF3099) - - - 0.000000000000000004958 94.0
TLS2_k127_1289601_12 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000036 62.0
TLS2_k127_1289601_13 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000003314 62.0
TLS2_k127_1289601_2 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 393.0
TLS2_k127_1289601_3 NADPH quinone reductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 382.0
TLS2_k127_1289601_4 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 359.0
TLS2_k127_1289601_5 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 311.0
TLS2_k127_1289601_6 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000149 289.0
TLS2_k127_1289601_7 SURF1-like protein - GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000000000000001243 195.0
TLS2_k127_1289601_8 BioY protein K03523 - - 0.0000000000000000000000000000000000000000000003504 175.0
TLS2_k127_1289601_9 Transcriptional regulator - - - 0.000000000000000000000000000002591 120.0
TLS2_k127_1292316_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 6.618e-194 614.0
TLS2_k127_1292316_1 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000008786 245.0
TLS2_k127_1308769_0 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 350.0
TLS2_k127_1308769_1 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 332.0
TLS2_k127_1308769_2 Glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006154 278.0
TLS2_k127_1308769_3 Protein of unknown function (DUF3117) - - - 0.000000000000000000000007071 104.0
TLS2_k127_1313056_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.335e-276 859.0
TLS2_k127_1313056_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009069,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0019842,GO:0020012,GO:0030170,GO:0030312,GO:0030682,GO:0036094,GO:0042133,GO:0042783,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0071944,GO:0075136,GO:0097159,GO:1901363,GO:1901564,GO:1901605 2.1.2.1 8.375e-231 730.0
TLS2_k127_1313056_10 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 380.0
TLS2_k127_1313056_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 360.0
TLS2_k127_1313056_12 inositol 2-dehydrogenase activity K16044 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0070402,GO:0097159,GO:0102497,GO:1901265,GO:1901363 1.1.1.371 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 346.0
TLS2_k127_1313056_13 Transcriptional regulator, DeoR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 349.0
TLS2_k127_1313056_14 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 338.0
TLS2_k127_1313056_15 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 336.0
TLS2_k127_1313056_16 PFAM cyclase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003537 274.0
TLS2_k127_1313056_17 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002897 272.0
TLS2_k127_1313056_18 D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000003563 273.0
TLS2_k127_1313056_19 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009148 255.0
TLS2_k127_1313056_2 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 531.0
TLS2_k127_1313056_20 2'-5' RNA ligase - - - 0.0000000000000000000000000000000000000000000000000000000002165 211.0
TLS2_k127_1313056_21 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000001178 224.0
TLS2_k127_1313056_22 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000929 221.0
TLS2_k127_1313056_23 - - - - 0.00000000000000000000000000000000000000000000000000000003355 213.0
TLS2_k127_1313056_24 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000001398 189.0
TLS2_k127_1313056_25 Ribonuclease K07058 - - 0.00000000000000000000000000000000000000000000000002142 200.0
TLS2_k127_1313056_26 Domain of unknown function (DUF309) K09763 - - 0.00000000000000000000000000000000000000000000000005754 187.0
TLS2_k127_1313056_27 Histidine kinase - - - 0.00000000000000000000000000000000003895 156.0
TLS2_k127_1313056_28 Evidence 4 Homologs of previously reported genes of K09981 - - 0.000000000000000000000000003256 113.0
TLS2_k127_1313056_29 - - - - 0.0000000000000000003915 96.0
TLS2_k127_1313056_3 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 495.0
TLS2_k127_1313056_30 - - - - 0.00000000000005535 83.0
TLS2_k127_1313056_31 CopC domain K07156,K14166 - - 0.00002168 56.0
TLS2_k127_1313056_4 Tryptophanyl-tRNA synthetase K01867 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 485.0
TLS2_k127_1313056_5 mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 481.0
TLS2_k127_1313056_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 469.0
TLS2_k127_1313056_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0040007,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 445.0
TLS2_k127_1313056_8 Belongs to the peptidase S51 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 419.0
TLS2_k127_1313056_9 Belongs to the GHMP kinase family. GalK subfamily K00849,K00965 - 2.7.1.6,2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 410.0
TLS2_k127_1353019_0 PFAM MMPL domain protein K06994 - - 1.327e-218 706.0
TLS2_k127_1353019_1 Protein of unknown function, DUF480 K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 542.0
TLS2_k127_1353019_10 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000006879 79.0
TLS2_k127_1353019_11 Transposase - - - 0.00000003488 55.0
TLS2_k127_1353019_12 - - - - 0.0002229 48.0
TLS2_k127_1353019_2 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 364.0
TLS2_k127_1353019_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 325.0
TLS2_k127_1353019_4 Glycoside-hydrolase family GH114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 298.0
TLS2_k127_1353019_5 Transcriptional regulatory protein, C terminal K07669,K07672 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 289.0
TLS2_k127_1353019_6 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007366 270.0
TLS2_k127_1353019_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007048 282.0
TLS2_k127_1353019_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000003758 225.0
TLS2_k127_1353019_9 HNH endonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000004413 142.0
TLS2_k127_139207_0 SMART alpha amylase, catalytic sub domain K01187 - 3.2.1.20 4.19e-217 694.0
TLS2_k127_139207_1 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 404.0
TLS2_k127_139207_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 365.0
TLS2_k127_139207_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 299.0
TLS2_k127_139207_4 ABC transporter - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000006333 169.0
TLS2_k127_139207_5 Single-strand binding protein family K03111 - - 0.000000000000000000000000004458 125.0
TLS2_k127_139207_6 Pfam:Pyridox_oxidase - - - 0.000000000001345 75.0
TLS2_k127_1394745_0 Protein of unknown function (DUF4011) - - - 0.0 1413.0
TLS2_k127_1394745_1 Methane/Phenol/Toluene Hydroxylase K18223 - 1.14.13.227 0.0 1114.0
TLS2_k127_1394745_10 Oxidoreductase FAD-binding domain K18225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 563.0
TLS2_k127_1394745_11 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 569.0
TLS2_k127_1394745_12 Major Facilitator Superfamily K18833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 518.0
TLS2_k127_1394745_13 His Kinase A (phosphoacceptor) domain K18351 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 514.0
TLS2_k127_1394745_14 Endonuclease Exonuclease Phosphatase K18353 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 484.0
TLS2_k127_1394745_15 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 462.0
TLS2_k127_1394745_16 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 456.0
TLS2_k127_1394745_17 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K18352 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 405.0
TLS2_k127_1394745_18 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 404.0
TLS2_k127_1394745_19 Endonuclease IV K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 358.0
TLS2_k127_1394745_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.3e-298 925.0
TLS2_k127_1394745_20 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 362.0
TLS2_k127_1394745_21 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 324.0
TLS2_k127_1394745_22 metal-sulfur cluster biosynthetic enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 302.0
TLS2_k127_1394745_23 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 289.0
TLS2_k127_1394745_24 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 296.0
TLS2_k127_1394745_25 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004329 294.0
TLS2_k127_1394745_26 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009 275.0
TLS2_k127_1394745_27 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001664 256.0
TLS2_k127_1394745_28 cold-shock protein K03704 - - 0.00000000000000000000000000000000000000000000000000000000000003654 217.0
TLS2_k127_1394745_29 MmoB/DmpM family K18226 - - 0.000000000000000000000000000000000000000000000008394 182.0
TLS2_k127_1394745_3 type III restriction enzyme, res subunit - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 4.93e-297 920.0
TLS2_k127_1394745_30 Protein of unknown function (DUF3039) - - - 0.00000000000000000000000000000000000000000007361 161.0
TLS2_k127_1394745_31 - - - - 0.0000000000000000000000000000000002315 137.0
TLS2_k127_1394745_32 DUF218 domain - - - 0.000000000000000000000000000000002822 135.0
TLS2_k127_1394745_33 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000002483 120.0
TLS2_k127_1394745_34 TIGRFAM hydrogenase maturation protease - - - 0.000000000000006734 82.0
TLS2_k127_1394745_35 Secreted K21471 - - 0.000001308 59.0
TLS2_k127_1394745_4 Multicopper oxidase K08100,K20219 - 1.10.3.4,1.3.3.5 1.437e-240 773.0
TLS2_k127_1394745_5 Methane/Phenol/Toluene Hydroxylase K18224 - 1.14.13.227 4.818e-230 715.0
TLS2_k127_1394745_6 Bacterial regulatory protein, Fis family - - - 1.312e-225 716.0
TLS2_k127_1394745_7 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006601 600.0
TLS2_k127_1394745_8 Zinc-binding dehydrogenase K18382 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 592.0
TLS2_k127_1394745_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 598.0
TLS2_k127_1423844_0 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 511.0
TLS2_k127_1423844_1 response regulator, receiver K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000007059 197.0
TLS2_k127_1423844_2 GAF domain - - - 0.00000000000000000000000000000000005312 156.0
TLS2_k127_1423844_3 GGDEF domain - - - 0.0000000000000000000000000001513 125.0
TLS2_k127_1423844_5 redox-active disulfide protein 2 - - - 0.00000000000000000000000003685 124.0
TLS2_k127_1423844_6 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000001184 112.0
TLS2_k127_1423844_7 HWE histidine kinase - - - 0.000000000001961 81.0
TLS2_k127_1432246_0 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 0.0 1681.0
TLS2_k127_1432246_1 assembly protein sufB K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 1.241e-287 886.0
TLS2_k127_1432246_10 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004603 259.0
TLS2_k127_1432246_11 - - - - 0.0000000000000000000000000000000000000000000000000000000002564 213.0
TLS2_k127_1432246_12 membrane - - - 0.000000000000000000000000000000000000000000000000000003568 196.0
TLS2_k127_1432246_13 metal-sulfur cluster biosynthetic enzyme - - - 0.00000000000000000000000000000000000000000000000000007157 187.0
TLS2_k127_1432246_14 Suf system fes assembly protein, nifu family K04488 - - 0.0000000000000000000000000000000000000000000000001227 188.0
TLS2_k127_1432246_15 Serine threonine-protein kinase pknK K13419 - 2.7.11.1 0.000000000000000000000000000000000000000006644 176.0
TLS2_k127_1432246_16 translation release factor activity - - - 0.000000000000000000000000000000000006993 146.0
TLS2_k127_1432246_17 Rieske-like [2Fe-2S] domain K05710 - - 0.0000000000000000000000000000003274 140.0
TLS2_k127_1432246_18 Belongs to the WXG100 family - - - 0.000000000000000000000002243 106.0
TLS2_k127_1432246_2 COG3209 Rhs family protein - - - 3.923e-276 889.0
TLS2_k127_1432246_20 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.0004539 51.0
TLS2_k127_1432246_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 571.0
TLS2_k127_1432246_4 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 521.0
TLS2_k127_1432246_5 ABC transporter (Permease) K09015 GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 492.0
TLS2_k127_1432246_6 FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 441.0
TLS2_k127_1432246_7 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 309.0
TLS2_k127_1432246_8 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 330.0
TLS2_k127_1432246_9 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003364 276.0
TLS2_k127_1469042_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 3.779e-301 937.0
TLS2_k127_1469042_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 5.713e-237 743.0
TLS2_k127_1469042_10 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 368.0
TLS2_k127_1469042_11 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 356.0
TLS2_k127_1469042_12 hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008478 321.0
TLS2_k127_1469042_13 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002109 277.0
TLS2_k127_1469042_14 ADP-ribose pyrophosphatase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000005989 267.0
TLS2_k127_1469042_15 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004262 266.0
TLS2_k127_1469042_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006442 259.0
TLS2_k127_1469042_17 Belongs to the DEAD box helicase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007677 271.0
TLS2_k127_1469042_18 copper ion homeostasis - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0008150,GO:0009279,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0044425,GO:0044462,GO:0044464,GO:0046930,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098796 - 0.000000000000000000000000000000000000000000000000000000000000000008825 236.0
TLS2_k127_1469042_19 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000002585 230.0
TLS2_k127_1469042_2 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 1.539e-203 649.0
TLS2_k127_1469042_20 Chorismate mutase type I K06208 - 5.4.99.5 0.0000000000000000000000000000000000005484 147.0
TLS2_k127_1469042_21 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03428,K07003,K15984 - 2.1.1.11,2.1.1.242 0.000000000000000000000000000000005404 138.0
TLS2_k127_1469042_22 Major facilitator Superfamily - - - 0.00000005626 54.0
TLS2_k127_1469042_3 Thiamin pyrophosphokinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 595.0
TLS2_k127_1469042_4 virulence factor MVIN family protein K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 617.0
TLS2_k127_1469042_5 chromosome partitioning K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 497.0
TLS2_k127_1469042_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 431.0
TLS2_k127_1469042_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 424.0
TLS2_k127_1469042_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 399.0
TLS2_k127_1469042_9 tyrosine recombinase K04763 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 388.0
TLS2_k127_1528319_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 521.0
TLS2_k127_1528319_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000002892 219.0
TLS2_k127_1528319_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000001136 186.0
TLS2_k127_1528319_3 - - - - 0.00000000000000000000000000000000000000005207 160.0
TLS2_k127_1528319_4 - - - - 0.0000000000000000000000000000001705 132.0
TLS2_k127_1535748_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K01990 - - 1.616e-288 914.0
TLS2_k127_1535748_1 Ferrous iron transport protein B C terminus K04759 - - 4.775e-212 680.0
TLS2_k127_1535748_10 Scramblase - - - 0.000000008524 67.0
TLS2_k127_1535748_11 Belongs to the ompA family K03286 - - 0.00000002011 68.0
TLS2_k127_1535748_12 FeoA - - - 0.000004152 55.0
TLS2_k127_1535748_2 ABC transporter (Permease) K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 372.0
TLS2_k127_1535748_3 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 342.0
TLS2_k127_1535748_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 298.0
TLS2_k127_1535748_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001272 234.0
TLS2_k127_1535748_6 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000003449 180.0
TLS2_k127_1535748_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000002618 155.0
TLS2_k127_1535748_8 RDD family - - - 0.00000000000000000000006624 111.0
TLS2_k127_1535748_9 - - - - 0.00000000003893 77.0
TLS2_k127_1556971_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1258.0
TLS2_k127_1556971_1 Heat shock 70 kDa protein K04043 GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 - 0.0 1002.0
TLS2_k127_1556971_10 Protein of unknown function (DUF1116) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 486.0
TLS2_k127_1556971_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 450.0
TLS2_k127_1556971_12 Peptidase family M20/M25/M40 K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 439.0
TLS2_k127_1556971_13 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 412.0
TLS2_k127_1556971_14 NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 417.0
TLS2_k127_1556971_15 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 394.0
TLS2_k127_1556971_16 TIM-barrel fold metal-dependent hydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 404.0
TLS2_k127_1556971_17 homocysteine S-methyltransferase K00547,K21169 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 353.0
TLS2_k127_1556971_18 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 331.0
TLS2_k127_1556971_19 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001342 284.0
TLS2_k127_1556971_2 Urocanase C-terminal domain K01712 - 4.2.1.49 4.741e-320 1002.0
TLS2_k127_1556971_20 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007448 264.0
TLS2_k127_1556971_21 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002936 259.0
TLS2_k127_1556971_22 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002241 261.0
TLS2_k127_1556971_23 MDMPI C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000002531 213.0
TLS2_k127_1556971_24 transcriptional regulator K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000612 203.0
TLS2_k127_1556971_25 Domain of unknown function (DUF4345) - - - 0.000000000000000000000000000000000000000000000002898 176.0
TLS2_k127_1556971_26 nitric oxide dioxygenase activity - - - 0.00000000000000000000000000000000000000000000113 171.0
TLS2_k127_1556971_27 OmpA family - - - 0.00000000000000000000000000000000000000002356 172.0
TLS2_k127_1556971_28 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000003432 153.0
TLS2_k127_1556971_29 ABC transporter - - - 0.0000000000000000000000000000000000001141 150.0
TLS2_k127_1556971_3 Nitrate reductase K02824 - - 7.553e-231 724.0
TLS2_k127_1556971_30 Transcriptional regulator PadR-like family K10947 - - 0.00000000000000000000000000000000001802 138.0
TLS2_k127_1556971_31 Cold shock protein domain K03704 - - 0.0000000000000000000000000000004806 126.0
TLS2_k127_1556971_32 Transcriptional regulator padr family - - - 0.0000000000000000000000000002331 118.0
TLS2_k127_1556971_33 Protein of unknown function (DUF2877) - - - 0.00000000000000000000002879 111.0
TLS2_k127_1556971_34 - - - - 0.000000000000000000004425 103.0
TLS2_k127_1556971_36 Protein of unknown function (DUF4235) - - - 0.0000000000000000001913 94.0
TLS2_k127_1556971_37 4Fe-4S single cluster domain - - - 0.000000000000001899 89.0
TLS2_k127_1556971_38 - - - - 0.0000001792 63.0
TLS2_k127_1556971_4 Aromatic amino acid lyase K01745 - 4.3.1.3 6.332e-228 723.0
TLS2_k127_1556971_5 Protein of unknown function (DUF1116) - - - 3.291e-198 648.0
TLS2_k127_1556971_6 transcriptional regulator K09684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 604.0
TLS2_k127_1556971_7 Predicted Permease Membrane Region K07085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 585.0
TLS2_k127_1556971_8 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 553.0
TLS2_k127_1556971_9 Formiminoglutamate deiminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 555.0
TLS2_k127_1587081_0 ABC transporter transmembrane region K06147 - - 1.448e-248 815.0
TLS2_k127_1587081_1 acyl-CoA dehydrogenase K09456 - - 1.79e-207 661.0
TLS2_k127_1587081_2 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 4.287e-195 621.0
TLS2_k127_1587081_3 ABC transporter transmembrane region K06147 - - 1.157e-194 647.0
TLS2_k127_1587081_4 Scramblase - - - 0.00000331 54.0
TLS2_k127_16135_0 IMP dehydrogenase GMP reductase K00088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.1.1.205 2.679e-218 700.0
TLS2_k127_16135_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 338.0
TLS2_k127_16135_10 - - - - 0.0000000000000000000000000000000000009185 152.0
TLS2_k127_16135_11 Stress responsive A/B Barrel Domain - - - 0.000000000000000000007573 98.0
TLS2_k127_16135_12 TOBE domain - - - 0.00000000000000004156 85.0
TLS2_k127_16135_13 zinc ion binding - - - 0.000000000000001269 85.0
TLS2_k127_16135_14 - - - - 0.000000000005082 74.0
TLS2_k127_16135_2 HAD hydrolase, family IIB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 330.0
TLS2_k127_16135_3 Prolyl oligopeptidase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 286.0
TLS2_k127_16135_4 molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001264 274.0
TLS2_k127_16135_5 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000091 267.0
TLS2_k127_16135_6 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009333 274.0
TLS2_k127_16135_7 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000006605 207.0
TLS2_k127_16135_8 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000001118 200.0
TLS2_k127_16135_9 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000008591 175.0
TLS2_k127_1623615_0 nitrogenase molybdenum-iron protein alpha chain K02586 - 1.18.6.1 1.947e-202 644.0
TLS2_k127_1623615_1 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 593.0
TLS2_k127_1623615_10 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000007431 108.0
TLS2_k127_1623615_11 Belongs to the globin family - - - 0.0001923 53.0
TLS2_k127_1623615_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 517.0
TLS2_k127_1623615_3 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 507.0
TLS2_k127_1623615_4 HMGL-like K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 491.0
TLS2_k127_1623615_5 Belongs to the peptidase M48B family K03799 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 464.0
TLS2_k127_1623615_6 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 469.0
TLS2_k127_1623615_7 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 467.0
TLS2_k127_1623615_8 FIST C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 421.0
TLS2_k127_1623615_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.0000000000000000000000000000000000000000874 156.0
TLS2_k127_1633522_0 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001785 295.0
TLS2_k127_1633522_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006377 307.0
TLS2_k127_1633522_2 DNA topoisomerase II activity K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000001416 246.0
TLS2_k127_1633522_3 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000479 203.0
TLS2_k127_1633522_4 - - - - 0.00000000000000000000008506 111.0
TLS2_k127_1652037_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 7.674e-277 876.0
TLS2_k127_1652037_1 exporter of polyketide K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 543.0
TLS2_k127_1652037_10 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000003953 226.0
TLS2_k127_1652037_11 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000002992 206.0
TLS2_k127_1652037_12 spore germination - - - 0.0000000000000000000000000000000000000000000000000006046 196.0
TLS2_k127_1652037_14 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000004397 186.0
TLS2_k127_1652037_15 Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000005152 167.0
TLS2_k127_1652037_16 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000003829 144.0
TLS2_k127_1652037_17 Phospholipase_D-nuclease N-terminal - - - 0.00000000000000000000000000000001172 131.0
TLS2_k127_1652037_18 - - - - 0.00000000000000000000000000000004606 138.0
TLS2_k127_1652037_19 - - - - 0.00000000000000000000000000000006634 134.0
TLS2_k127_1652037_2 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 544.0
TLS2_k127_1652037_20 Chemoreceptor zinc-binding domain - - - 0.00000000000000000000000005457 113.0
TLS2_k127_1652037_21 - - - - 0.000000000000008983 84.0
TLS2_k127_1652037_22 - - - - 0.00000000000008317 76.0
TLS2_k127_1652037_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 484.0
TLS2_k127_1652037_4 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 317.0
TLS2_k127_1652037_5 Pentapeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 315.0
TLS2_k127_1652037_6 phosphatidylcholine synthase K01004 - 2.7.8.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 310.0
TLS2_k127_1652037_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 317.0
TLS2_k127_1652037_8 PFAM CoA-binding domain protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000316 239.0
TLS2_k127_1652037_9 signal recognition particle binding K06398,K06945 - - 0.000000000000000000000000000000000000000000000000000000000000003159 222.0
TLS2_k127_1727815_0 polyketide synthase - - - 0.0 1999.0
TLS2_k127_1727815_1 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0 1266.0
TLS2_k127_1727815_2 Phosphopantetheine attachment site - - - 0.0 1160.0
TLS2_k127_1727815_3 Non-ribosomal peptide synthetase modules and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 553.0
TLS2_k127_1732600_0 Enoylreductase K12436,K16396,K16397 - - 0.0 1504.0
TLS2_k127_1732600_1 polyketide synthase - - - 0.0 1163.0
TLS2_k127_1732600_2 Drug exporters of the RND superfamily K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 571.0
TLS2_k127_1732600_3 Integrase core domain K07497 - - 0.0005809 42.0
TLS2_k127_1736465_0 decarboxylase - - - 1.351e-196 621.0
TLS2_k127_1736465_1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 358.0
TLS2_k127_1736465_2 Domain of unknown function (DUF1727) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 327.0
TLS2_k127_1736465_3 PFAM CobB CobQ domain protein glutamine amidotransferase K07009 - - 0.000000000000000000000000000000000000000000000000000000000000000002865 245.0
TLS2_k127_1736465_4 Protein of unknown function (DUF3263) - - - 0.00000000000000000000000000000000006663 136.0
TLS2_k127_1736465_5 Cold shock protein K03704 - - 0.000000000000000000000000000000003047 129.0
TLS2_k127_1736465_6 DNA polymerase K02335 - 2.7.7.7 0.0000000000000000000000000001649 117.0
TLS2_k127_1736465_7 LytR cell envelope-related transcriptional attenuator - - - 0.000000000005927 74.0
TLS2_k127_1747845_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 429.0
TLS2_k127_1747845_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 379.0
TLS2_k127_1747845_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000001219 242.0
TLS2_k127_1747845_3 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000006375 222.0
TLS2_k127_1747845_4 Alpha/beta-hydrolase family N-terminus - - - 0.000000000000001267 79.0
TLS2_k127_1764835_0 Uroporphyrinogen-III synthase K01719,K13542 - 2.1.1.107,4.2.1.75 4.056e-253 794.0
TLS2_k127_1764835_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 484.0
TLS2_k127_1764835_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0008150,GO:0040007 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 465.0
TLS2_k127_1764835_3 HAD-superfamily subfamily IB hydrolase, TIGR01490 - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 355.0
TLS2_k127_1764835_4 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 336.0
TLS2_k127_1764835_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 315.0
TLS2_k127_1764835_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000002176 168.0
TLS2_k127_1764835_7 PFAM Glutaredoxin 2 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000007313 112.0
TLS2_k127_1822911_0 Dehydrogenase K00382 - 1.8.1.4 4.577e-238 747.0
TLS2_k127_1822911_1 MMPL family K06994 - - 1.706e-214 690.0
TLS2_k127_1822911_10 - - - - 0.000000000000000000000000000009117 128.0
TLS2_k127_1822911_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 2.057e-195 636.0
TLS2_k127_1822911_3 epimerase K07071 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0030312,GO:0031073,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0046906,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 362.0
TLS2_k127_1822911_4 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 354.0
TLS2_k127_1822911_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 327.0
TLS2_k127_1822911_6 Belongs to the peptidase S51 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 321.0
TLS2_k127_1822911_7 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 308.0
TLS2_k127_1822911_8 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000006264 222.0
TLS2_k127_1822911_9 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000006676 132.0
TLS2_k127_1875504_0 carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1836.0
TLS2_k127_1875504_1 ABC transporter K02021,K06147,K16786,K16787 - - 1.8e-243 774.0
TLS2_k127_1875504_10 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 545.0
TLS2_k127_1875504_11 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 507.0
TLS2_k127_1875504_12 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 428.0
TLS2_k127_1875504_13 ATP phosphoribosyltransferase K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 404.0
TLS2_k127_1875504_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01657,K02500 GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 417.0
TLS2_k127_1875504_15 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 - 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 420.0
TLS2_k127_1875504_16 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016020,GO:0016070,GO:0034641,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 400.0
TLS2_k127_1875504_17 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 365.0
TLS2_k127_1875504_18 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 351.0
TLS2_k127_1875504_19 Nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 315.0
TLS2_k127_1875504_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 6.13e-224 717.0
TLS2_k127_1875504_20 N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 323.0
TLS2_k127_1875504_21 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 295.0
TLS2_k127_1875504_22 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 295.0
TLS2_k127_1875504_23 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000914 280.0
TLS2_k127_1875504_24 Dihydroorotate oxidase K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009834 289.0
TLS2_k127_1875504_25 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008197 279.0
TLS2_k127_1875504_26 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000008602 217.0
TLS2_k127_1875504_27 molybdopterin cofactor binding - - - 0.000000000000000000000000000000000000000000000000000000000002504 229.0
TLS2_k127_1875504_28 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000006417 207.0
TLS2_k127_1875504_29 DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000001744 212.0
TLS2_k127_1875504_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.5.1.6 1.603e-221 692.0
TLS2_k127_1875504_30 membrane - - - 0.0000000000000000000000000000000000000000000004435 172.0
TLS2_k127_1875504_31 integration host factor - - - 0.000000000000000000000000000000000000000000001065 166.0
TLS2_k127_1875504_32 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 0.000000000000000000000000000000000000000001445 158.0
TLS2_k127_1875504_33 uridine kinase - - - 0.00000000000000000000000000000000000000005645 169.0
TLS2_k127_1875504_34 Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139 3.6.1.31 0.0000000000000000000000000000000000000002203 154.0
TLS2_k127_1875504_35 Methylamine utilisation protein MauE - - - 0.0000000000000000000000000000000002866 145.0
TLS2_k127_1875504_36 Bacterial PH domain - - - 0.000000000000000000000000000000000679 138.0
TLS2_k127_1875504_37 RDD domain containing protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000004083 127.0
TLS2_k127_1875504_38 Tryptophan-associated transmembrane protein (Trp_oprn_chp) - - - 0.00000000000000000000003907 108.0
TLS2_k127_1875504_39 Protein of unknown function (DUF952) K00799,K01560,K21420 - 2.3.2.29,2.5.1.18,3.8.1.2 0.00000000000000000000274 106.0
TLS2_k127_1875504_4 ABC transporter transmembrane region - - - 3.821e-218 693.0
TLS2_k127_1875504_40 Psort location Cytoplasmic, score - - - 0.000000000000000000009058 109.0
TLS2_k127_1875504_41 - - - - 0.00000000000004451 86.0
TLS2_k127_1875504_42 - - - - 0.0000000000005976 77.0
TLS2_k127_1875504_43 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.4.2.9 0.00000005577 54.0
TLS2_k127_1875504_45 - - - - 0.000355 46.0
TLS2_k127_1875504_46 Interferon-induced transmembrane protein - - - 0.0004185 44.0
TLS2_k127_1875504_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 4.992e-216 687.0
TLS2_k127_1875504_6 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 8.811e-215 678.0
TLS2_k127_1875504_7 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 626.0
TLS2_k127_1875504_8 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 542.0
TLS2_k127_1875504_9 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 554.0
TLS2_k127_1884360_0 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 515.0
TLS2_k127_1884360_1 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 509.0
TLS2_k127_1884360_2 transcriptional regulator K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 295.0
TLS2_k127_1884360_3 Nitroreductase family K09019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004715 259.0
TLS2_k127_1884360_4 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000009795 201.0
TLS2_k127_1884360_5 PFAM NLP P60 protein K21471 - - 0.00000000000000000000001685 104.0
TLS2_k127_1908213_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 6.635e-264 826.0
TLS2_k127_1908213_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 512.0
TLS2_k127_1908213_2 S-adenosylhomocysteine deaminase activity K01485,K03365 GO:0003674,GO:0003824,GO:0004131,GO:0005488,GO:0005506,GO:0005515,GO:0006139,GO:0006206,GO:0006208,GO:0006209,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0019439,GO:0019858,GO:0034641,GO:0035888,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.4.1,3.5.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 452.0
TLS2_k127_1908213_3 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 320.0
TLS2_k127_1908213_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000008392 127.0
TLS2_k127_1908213_5 Helix-turn-helix XRE-family like proteins - - - 0.00000002594 57.0
TLS2_k127_1917085_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 0.0 1336.0
TLS2_k127_1917085_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1071.0
TLS2_k127_1917085_10 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000001292 216.0
TLS2_k127_1917085_11 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000003025 196.0
TLS2_k127_1917085_12 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000008601 183.0
TLS2_k127_1917085_13 anti-sigma regulatory factor - - - 0.000000000000000000000003485 106.0
TLS2_k127_1917085_14 Protein of unknown function (DUF742) - - - 0.000000000000000004259 89.0
TLS2_k127_1917085_16 - - - - 0.000000000000672 73.0
TLS2_k127_1917085_17 Protein of unknown function (DUF4244) - - - 0.00000002172 66.0
TLS2_k127_1917085_18 DNA integration K14059 - - 0.0000001378 54.0
TLS2_k127_1917085_19 TIGRFAM helicase secretion neighborhood TadE-like protein - - - 0.0000002199 65.0
TLS2_k127_1917085_2 Domain of unknown function (DUF1998) K06877 - - 2.5e-323 1024.0
TLS2_k127_1917085_20 Type II secretion system (T2SS), protein F - - - 0.00003299 53.0
TLS2_k127_1917085_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 5.519e-220 713.0
TLS2_k127_1917085_4 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 583.0
TLS2_k127_1917085_5 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 567.0
TLS2_k127_1917085_6 DNA polymerase III K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 535.0
TLS2_k127_1917085_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 488.0
TLS2_k127_1917085_8 ATP- GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 347.0
TLS2_k127_1917085_9 Roadblock lc7 family protein K07131 - - 0.000000000000000000000000000000000000000000000000000000000000006896 235.0
TLS2_k127_1934689_0 Large subunit K06281 - 1.12.99.6 3.395e-255 798.0
TLS2_k127_1934689_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.3.14 9.393e-209 653.0
TLS2_k127_1934689_10 Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.000000000000000000000000000000000000000000000006704 190.0
TLS2_k127_1934689_11 spore germination K03605 - - 0.00000000000000000000000000000000001133 153.0
TLS2_k127_1934689_12 Ribosomal protein L31 K02909 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000004567 141.0
TLS2_k127_1934689_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000001133 115.0
TLS2_k127_1934689_14 nickel cation binding K04651 - - 0.000000000000000000000002556 110.0
TLS2_k127_1934689_15 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex - - - 0.000000000000000008586 86.0
TLS2_k127_1934689_16 - K02116 - - 0.00000006044 61.0
TLS2_k127_1934689_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 549.0
TLS2_k127_1934689_3 PFAM Glycosyl transferase family 4 K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 466.0
TLS2_k127_1934689_4 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 409.0
TLS2_k127_1934689_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 312.0
TLS2_k127_1934689_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000154 295.0
TLS2_k127_1934689_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006785 292.0
TLS2_k127_1934689_8 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000001268 246.0
TLS2_k127_1934689_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000004009 204.0
TLS2_k127_1953860_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1722.0
TLS2_k127_1953860_1 AAA ATPase forming ring-shaped complexes K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 1.944e-279 866.0
TLS2_k127_1953860_10 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 514.0
TLS2_k127_1953860_11 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 494.0
TLS2_k127_1953860_12 PAC2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 475.0
TLS2_k127_1953860_13 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 428.0
TLS2_k127_1953860_14 RecB family exonuclease K07465 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 414.0
TLS2_k127_1953860_15 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 368.0
TLS2_k127_1953860_16 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 364.0
TLS2_k127_1953860_17 phosphoglycerate mutase K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 336.0
TLS2_k127_1953860_18 Phosphatidylinositol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 325.0
TLS2_k127_1953860_19 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003215 285.0
TLS2_k127_1953860_2 extracellular solute-binding protein, family 5 K02035 - - 2.128e-262 824.0
TLS2_k127_1953860_20 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002893 273.0
TLS2_k127_1953860_21 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002308 258.0
TLS2_k127_1953860_22 - - - - 0.0000000000000000000000002563 117.0
TLS2_k127_1953860_23 - - - - 0.0000000000000001527 88.0
TLS2_k127_1953860_3 ABC transporter (Permease) K02004 - - 8.482e-258 819.0
TLS2_k127_1953860_4 amino acid K03294 - - 1.727e-214 681.0
TLS2_k127_1953860_5 Peptidase family M28 - - - 3.503e-204 642.0
TLS2_k127_1953860_6 Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 560.0
TLS2_k127_1953860_7 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 547.0
TLS2_k127_1953860_8 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 531.0
TLS2_k127_1953860_9 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 517.0
TLS2_k127_1964130_0 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 GO:0002790,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0020012,GO:0030312,GO:0030682,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0040007,GO:0042783,GO:0042886,GO:0043207,GO:0044110,GO:0044116,GO:0044117,GO:0044315,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136 - 0.0 1210.0
TLS2_k127_1964130_1 PFAM Glycosyl transferase, family - - - 2.36e-213 694.0
TLS2_k127_1964130_10 NUDIX domain - - - 0.000000001234 68.0
TLS2_k127_1964130_11 - - - - 0.0000002076 64.0
TLS2_k127_1964130_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 590.0
TLS2_k127_1964130_3 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 530.0
TLS2_k127_1964130_4 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 421.0
TLS2_k127_1964130_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 350.0
TLS2_k127_1964130_6 PFAM Ferric reductase domain protein transmembrane component domain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000009851 233.0
TLS2_k127_1964130_7 electron transfer activity K05337 - - 0.000000000000004172 83.0
TLS2_k127_1964130_9 oxidoreductase - - - 0.0000000000004805 80.0
TLS2_k127_1969981_0 Phage tail sheath C-terminal domain K06907 - - 4.504e-263 824.0
TLS2_k127_1969981_1 Phage tail sheath C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 531.0
TLS2_k127_1969981_10 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000005203 207.0
TLS2_k127_1969981_11 - K03646 - - 0.00000000000000000000000002084 128.0
TLS2_k127_1969981_2 - K06905 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 508.0
TLS2_k127_1969981_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 515.0
TLS2_k127_1969981_4 positive regulation of growth rate K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 315.0
TLS2_k127_1969981_5 Rhs element Vgr protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 306.0
TLS2_k127_1969981_6 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002112 295.0
TLS2_k127_1969981_7 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001557 267.0
TLS2_k127_1969981_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003352 266.0
TLS2_k127_1969981_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000359 216.0
TLS2_k127_1989487_0 Carboxyl transferase domain K01966 GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494 2.1.3.15,6.4.1.3 7.246e-294 909.0
TLS2_k127_1989487_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 555.0
TLS2_k127_1989487_2 cell envelope-related transcriptional attenuator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 428.0
TLS2_k127_1989487_3 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 376.0
TLS2_k127_1989487_4 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005705 285.0
TLS2_k127_1989487_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0008150,GO:0040007 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000002606 257.0
TLS2_k127_1989487_6 PFAM GtrA family protein - - - 0.00000000000000000000000000000000000000000000002269 178.0
TLS2_k127_1989487_7 PFAM membrane-flanked domain - - - 0.0000000000000000000000000000000000000000000001049 175.0
TLS2_k127_1989487_8 Golgi phosphoprotein 3 (GPP34) - - - 0.00000000000002046 82.0
TLS2_k127_2000_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 7.163e-254 786.0
TLS2_k127_2000_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 2.22e-204 679.0
TLS2_k127_2000_2 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 471.0
TLS2_k127_2000_3 molybdopterin K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 336.0
TLS2_k127_2000_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000007979 198.0
TLS2_k127_2000_5 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000008151 189.0
TLS2_k127_2000_6 methyltransferase activity - - - 0.000000000000000000000000000000000008751 143.0
TLS2_k127_2006048_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 0.0 1613.0
TLS2_k127_2006048_1 biosynthesis protein E - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 468.0
TLS2_k127_2006048_10 Alpha/beta hydrolase family K21193 - - 0.000000000000000002002 95.0
TLS2_k127_2006048_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000003256 91.0
TLS2_k127_2006048_12 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.00000000000003256 77.0
TLS2_k127_2006048_14 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000003562 53.0
TLS2_k127_2006048_15 Electron transfer flavoprotein K03521 - - 0.0007747 43.0
TLS2_k127_2006048_2 biosynthesis protein E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 432.0
TLS2_k127_2006048_3 Belongs to the NOS family. Bacterial NOS oxygenase subfamily K00491 - 1.14.14.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 406.0
TLS2_k127_2006048_5 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000000000005108 160.0
TLS2_k127_2006048_6 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000009122 158.0
TLS2_k127_2006048_7 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000005326 150.0
TLS2_k127_2006048_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000001757 135.0
TLS2_k127_2006048_9 COG1063 Threonine dehydrogenase and related Zn-dependent K00148 - 1.2.1.46 0.0000000000000000000000001636 111.0
TLS2_k127_2041338_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1043.0
TLS2_k127_2041338_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1011.0
TLS2_k127_2041338_10 Displays ATPase and GTPase activities K06958 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 380.0
TLS2_k127_2041338_11 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 366.0
TLS2_k127_2041338_12 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 348.0
TLS2_k127_2041338_13 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 325.0
TLS2_k127_2041338_14 PAS domain containing protein K03406,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000239 265.0
TLS2_k127_2041338_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001702 263.0
TLS2_k127_2041338_16 Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters - - - 0.00000000000000000000000000000000000000000000000000000000000001727 216.0
TLS2_k127_2041338_17 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000001536 178.0
TLS2_k127_2041338_18 Preprotein translocase SecG subunit K03075 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000002965 119.0
TLS2_k127_2041338_19 - - - - 0.0000000000000000000000000003938 129.0
TLS2_k127_2041338_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 6.303e-275 881.0
TLS2_k127_2041338_20 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000002278 115.0
TLS2_k127_2041338_21 - - - - 0.00000000006932 70.0
TLS2_k127_2041338_3 Phosphoglycerate kinase K00927,K01803 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 600.0
TLS2_k127_2041338_4 May be required for sporulation K09762 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 589.0
TLS2_k127_2041338_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 565.0
TLS2_k127_2041338_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 494.0
TLS2_k127_2041338_7 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 486.0
TLS2_k127_2041338_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 405.0
TLS2_k127_2041338_9 dehydrogenase subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 386.0
TLS2_k127_208130_0 Aminotransferase class I and II K05825 - - 1.209e-194 631.0
TLS2_k127_208130_1 N-acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 385.0
TLS2_k127_208130_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 310.0
TLS2_k127_208130_3 belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000000000000005349 173.0
TLS2_k127_208130_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000002199 82.0
TLS2_k127_208130_5 Oxygen tolerance - - - 0.0004736 42.0
TLS2_k127_2151229_0 Carbamoyltransferase C-terminus K00612 - - 1.234e-246 778.0
TLS2_k127_2151229_1 RmlD substrate binding domain K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 516.0
TLS2_k127_2151229_2 D,D-heptose 1,7-bisphosphate phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 490.0
TLS2_k127_2151229_3 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 435.0
TLS2_k127_2151229_4 Glycosyl transferases group 1 K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 429.0
TLS2_k127_2151229_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 394.0
TLS2_k127_2151229_6 PFAM glycosyl transferase family 9 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 374.0
TLS2_k127_2151229_7 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000398 297.0
TLS2_k127_2151229_8 SIS domain K03271,K15669 - 2.7.7.71,5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000002052 241.0
TLS2_k127_2151229_9 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000000000000000003124 134.0
TLS2_k127_2187864_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1458.0
TLS2_k127_2187864_1 amino acid - - - 9.129e-313 974.0
TLS2_k127_2187864_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000002468 233.0
TLS2_k127_2187864_11 DNA-binding protein - GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000004102 236.0
TLS2_k127_2187864_12 Domain of unknown function (DUF4193) - - - 0.00000000000000000000000000000000000000000000000004005 179.0
TLS2_k127_2187864_13 Nucleic acid binding, OB-fold, tRNA - - - 0.00000000000000000000000000000000000000000000001058 177.0
TLS2_k127_2187864_14 Protein of unknown function (DUF3159) - - - 0.0000000000000000000000000000000000000000004281 177.0
TLS2_k127_2187864_15 Protein of unknown function (DUF3093) - - - 0.00000000000000000000000000782 121.0
TLS2_k127_2187864_16 - - - - 0.000001013 56.0
TLS2_k127_2187864_17 geranylgeranyl reductase K21401 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 1.3.99.38 0.0000657 53.0
TLS2_k127_2187864_2 ABC-type xylose transport system, periplasmic component K10543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 512.0
TLS2_k127_2187864_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 462.0
TLS2_k127_2187864_4 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 439.0
TLS2_k127_2187864_5 Ferrochelatase K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 447.0
TLS2_k127_2187864_6 PFAM TrkA-N domain protein K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 367.0
TLS2_k127_2187864_7 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 349.0
TLS2_k127_2187864_8 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 316.0
TLS2_k127_2187864_9 Protein of unknown function (DUF3710) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005406 252.0
TLS2_k127_2274846_0 Contains 3'-5'exonuclease domain K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 5.745e-213 701.0
TLS2_k127_2274846_1 PFAM Glycosyl transferase, group 1 K13668 - 2.4.1.346 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 499.0
TLS2_k127_2274846_10 Flp/Fap pilin component - - - 0.00003086 51.0
TLS2_k127_2274846_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 372.0
TLS2_k127_2274846_3 RNA-binding protein containing a PIN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002147 274.0
TLS2_k127_2274846_4 aminopeptidase N - - - 0.000000000000000000000000000000000000000000000007345 189.0
TLS2_k127_2274846_5 NlpC/P60 family K21471 - - 0.00000000000000000000000000000000000000000000003012 184.0
TLS2_k127_2274846_6 AsnC family transcriptional regulator - - - 0.000000000000000000000000000000000007866 138.0
TLS2_k127_2274846_7 oligosaccharyl transferase activity - - - 0.0000000000000000000008638 110.0
TLS2_k127_2274846_8 Flp/Fap pilin component - - - 0.00000000000002637 75.0
TLS2_k127_2274846_9 - - - - 0.0000000000003387 76.0
TLS2_k127_2290279_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 4.382e-240 753.0
TLS2_k127_2290279_1 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 559.0
TLS2_k127_2290279_10 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 312.0
TLS2_k127_2290279_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000004277 218.0
TLS2_k127_2290279_12 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000227 220.0
TLS2_k127_2290279_13 Thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000001145 199.0
TLS2_k127_2290279_14 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000000000000002632 181.0
TLS2_k127_2290279_15 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000001255 133.0
TLS2_k127_2290279_16 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000001016 119.0
TLS2_k127_2290279_17 - - - - 0.0000000000000000000000001364 109.0
TLS2_k127_2290279_18 TIGRFAM exopolysaccharide transport protein family K16692 - - 0.000000000000000000000007107 118.0
TLS2_k127_2290279_19 Protein of unknown function (DUF2892) - - - 0.0000003761 55.0
TLS2_k127_2290279_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 462.0
TLS2_k127_2290279_3 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 400.0
TLS2_k127_2290279_4 MviN-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 412.0
TLS2_k127_2290279_5 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 380.0
TLS2_k127_2290279_6 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 370.0
TLS2_k127_2290279_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 375.0
TLS2_k127_2290279_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 353.0
TLS2_k127_2290279_9 Putative zinc-finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 311.0
TLS2_k127_2297910_0 AAA-like domain - - - 0.0 1339.0
TLS2_k127_2297910_1 hydrolase, family 65, central catalytic K05342 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944 2.4.1.64 0.0 1043.0
TLS2_k127_2297910_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 561.0
TLS2_k127_2297910_4 Haloacid dehalogenase-like hydrolase - GO:0003674,GO:0003824,GO:0008801,GO:0016853,GO:0016866,GO:0016868 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 308.0
TLS2_k127_2297910_5 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000000000000001913 214.0
TLS2_k127_2297910_6 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000000000002385 203.0
TLS2_k127_2297910_7 - - - - 0.00000000000000000000000000000000000000000005175 169.0
TLS2_k127_2297910_9 - - - - 0.00004045 52.0
TLS2_k127_2317330_0 Oxidoreductase FAD-binding domain K00523,K00529,K02639,K16246 - 1.17.1.1,1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 467.0
TLS2_k127_2317330_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 451.0
TLS2_k127_2317330_2 Haem-degrading - - - 0.0000000000000000000000000000000000000000009102 173.0
TLS2_k127_2317330_3 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000001095 126.0
TLS2_k127_2319637_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 480.0
TLS2_k127_2319637_1 Arabinose efflux permease family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 481.0
TLS2_k127_2319637_2 helix_turn_helix, Deoxyribose operon repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 410.0
TLS2_k127_2319637_3 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000002627 222.0
TLS2_k127_2319637_4 transcriptional regulator - - - 0.0000000000000000000000000000000000007328 144.0
TLS2_k127_2319637_5 Phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000000000000000000000008991 139.0
TLS2_k127_2319637_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000003657 91.0
TLS2_k127_2319637_7 - - - - 0.00000000000000001836 91.0
TLS2_k127_2319637_8 - - - - 0.0000005352 53.0
TLS2_k127_2362172_0 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 9.662e-240 748.0
TLS2_k127_2362172_1 myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 1.966e-206 645.0
TLS2_k127_2362172_10 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004379 269.0
TLS2_k127_2362172_11 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000002008 264.0
TLS2_k127_2362172_12 Belongs to the NUDIX hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004669 229.0
TLS2_k127_2362172_13 belongs to the sigma-70 factor family, ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000005079 228.0
TLS2_k127_2362172_14 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007554 213.0
TLS2_k127_2362172_15 Family of unknown function (DUF5318) - - - 0.000000000000000000000000000000000000000000000004758 178.0
TLS2_k127_2362172_16 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000085 171.0
TLS2_k127_2362172_17 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000008163 131.0
TLS2_k127_2362172_19 Pyridine nucleotide-disulphide oxidoreductase K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000007969 80.0
TLS2_k127_2362172_2 penicillin-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 502.0
TLS2_k127_2362172_3 MATE efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 479.0
TLS2_k127_2362172_4 Integral membrane protein MviN K03980 GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 475.0
TLS2_k127_2362172_5 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 430.0
TLS2_k127_2362172_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 377.0
TLS2_k127_2362172_7 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 383.0
TLS2_k127_2362172_8 single-stranded DNA-binding protein K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003237 274.0
TLS2_k127_2362172_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001677 271.0
TLS2_k127_2448180_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 600.0
TLS2_k127_2448180_1 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 505.0
TLS2_k127_2448180_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 494.0
TLS2_k127_2448180_3 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 353.0
TLS2_k127_2448180_4 UTRA K03489,K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003152 277.0
TLS2_k127_2448180_5 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000001936 223.0
TLS2_k127_2448180_8 Amino acid permease - - - 0.0000000005207 63.0
TLS2_k127_2453568_0 Domain of unknown function (DUF1929) - - - 2.507e-270 853.0
TLS2_k127_2453568_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 1.277e-224 707.0
TLS2_k127_2453568_2 Animal haem peroxidase - - - 2.151e-206 662.0
TLS2_k127_2453568_3 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 492.0
TLS2_k127_2453568_4 Peptidase family S58 K18572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 359.0
TLS2_k127_2453568_5 Protein of unknown function (DUF3618) - - - 0.00000000000000000000000000000000003555 147.0
TLS2_k127_2453568_6 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000000000000000001987 135.0
TLS2_k127_2453568_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000000000000000000001287 117.0
TLS2_k127_2457810_0 Sulfate transporter K03321 GO:0000103,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008272,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0019001,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0097159,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 620.0
TLS2_k127_2457810_1 DeoR C terminal sensor domain K03436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 317.0
TLS2_k127_2457810_2 Belongs to the carbohydrate kinase PfkB family K00882 - 2.7.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 314.0
TLS2_k127_2457810_3 C4-dicarboxylate transporter malic acid transport protein K03304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 312.0
TLS2_k127_2457810_4 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006539 240.0
TLS2_k127_2457810_5 Phosphotransferase System K02768,K02769,K02770 - 2.7.1.202 0.00000000000000000000000000000000000000000000000000000000003144 209.0
TLS2_k127_2457810_6 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768 - 2.7.1.202 0.00000000000000000000000000000000000000000000000000000206 194.0
TLS2_k127_2457810_7 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000005581 190.0
TLS2_k127_2457810_8 - - - - 0.000000000000000000000000000000000009043 145.0
TLS2_k127_2457810_9 - - - - 0.0000000001515 74.0
TLS2_k127_2467730_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 1.339e-276 861.0
TLS2_k127_2467730_1 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 2.217e-222 699.0
TLS2_k127_2467730_10 TIGRFAM DNA binding domain protein, excisionase family - - - 0.0000000000000000000000000000000000003293 141.0
TLS2_k127_2467730_11 - - - - 0.000000000000000000001228 108.0
TLS2_k127_2467730_12 Protein of unknown function (DUF3073) - - - 0.00000000000001389 80.0
TLS2_k127_2467730_13 - - - - 0.000000007219 68.0
TLS2_k127_2467730_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 2.465e-217 692.0
TLS2_k127_2467730_3 Transcriptional regulator K09684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 557.0
TLS2_k127_2467730_4 Belongs to the ABC transporter superfamily K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 548.0
TLS2_k127_2467730_5 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 511.0
TLS2_k127_2467730_6 PFAM extracellular solute-binding protein family 1 K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 487.0
TLS2_k127_2467730_7 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 376.0
TLS2_k127_2467730_8 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 357.0
TLS2_k127_2467730_9 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000002448 213.0
TLS2_k127_2476780_0 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000001587 182.0
TLS2_k127_2476780_1 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000000001884 115.0
TLS2_k127_2484832_0 Major facilitator Superfamily K07001 - - 3.67e-208 659.0
TLS2_k127_2484832_1 4Fe-4S binding domain - - - 3.787e-199 623.0
TLS2_k127_2484832_10 Bacterial regulatory proteins, tetR family - - - 0.000005548 51.0
TLS2_k127_2484832_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 577.0
TLS2_k127_2484832_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 447.0
TLS2_k127_2484832_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 459.0
TLS2_k127_2484832_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 387.0
TLS2_k127_2484832_6 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 271.0
TLS2_k127_2484832_7 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000003159 239.0
TLS2_k127_2484832_8 phosphorelay sensor kinase activity K03406 - - 0.00000000000000000000000001669 115.0
TLS2_k127_2484832_9 Metallo-beta-lactamase superfamily - - - 0.00000000007375 70.0
TLS2_k127_2505815_0 PFAM alpha amylase, catalytic K05341 - 2.4.1.4 6.617e-218 705.0
TLS2_k127_2505815_1 Flagellar basal body protein FlaE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 413.0
TLS2_k127_2505815_2 MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 352.0
TLS2_k127_2505815_3 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 338.0
TLS2_k127_2505815_4 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 321.0
TLS2_k127_2505815_5 Flagellar basal body-associated protein FliL K02415 - - 0.000000000000000000000000002619 119.0
TLS2_k127_2505815_6 Flagellar hook capping protein K02389 - - 0.00000000000000000000001495 109.0
TLS2_k127_2505815_7 Flagellar protein (FlbD) K02385 - - 0.000000000000000001413 90.0
TLS2_k127_2520306_0 phosphate starvation-inducible protein PhoH K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 558.0
TLS2_k127_2520306_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 555.0
TLS2_k127_2520306_10 HIT domain K02503 - - 0.000000000000000000000000000000000000005058 152.0
TLS2_k127_2520306_11 Sporulation and spore germination - - - 0.000000000000000000000000000001185 142.0
TLS2_k127_2520306_12 Domain of unknown function (DUF4870) K09940 - - 0.00000000000000000000000000004626 125.0
TLS2_k127_2520306_13 Immunoglobulin-like domain of bacterial spore germination - - - 0.000000000000002932 88.0
TLS2_k127_2520306_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 505.0
TLS2_k127_2520306_3 Cbs domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 511.0
TLS2_k127_2520306_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 473.0
TLS2_k127_2520306_5 Protein of unknown function (DUF3097) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 383.0
TLS2_k127_2520306_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001055 259.0
TLS2_k127_2520306_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000001438 258.0
TLS2_k127_2520306_8 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000005006 186.0
TLS2_k127_2520306_9 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000005335 166.0
TLS2_k127_2528862_0 Non-ribosomal peptide synthetase modules and related proteins K13611,K13614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 621.0
TLS2_k127_2528862_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 387.0
TLS2_k127_2528862_2 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 332.0
TLS2_k127_2528862_3 Cobalt ABC transporter K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003506 264.0
TLS2_k127_2528862_4 SMART CheW-like protein K03408 - - 0.0000000000000000000000000000000000005867 149.0
TLS2_k127_2528862_5 Pfam:DUF461 K09796 - - 0.0000000000000000000000000179 121.0
TLS2_k127_2528862_6 cobalamin binding K22491 - - 0.00000000000000006135 92.0
TLS2_k127_2554695_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 6.525e-234 744.0
TLS2_k127_2554695_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 608.0
TLS2_k127_2554695_10 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000005649 174.0
TLS2_k127_2554695_2 Domain of unknown function (DUF4162) K18232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 396.0
TLS2_k127_2554695_3 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 383.0
TLS2_k127_2554695_4 Transport permease protein K18233 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001636 294.0
TLS2_k127_2554695_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001832 238.0
TLS2_k127_2554695_6 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000273 214.0
TLS2_k127_2554695_7 Domain of unknown function (DUF1905) - - - 0.000000000000000000000000000000000000000000000000000009131 192.0
TLS2_k127_2554695_8 DNA synthesis involved in DNA repair - - - 0.0000000000000000000000000000000000000000000000002679 184.0
TLS2_k127_2554695_9 phosphatase - - - 0.0000000000000000000000000000000000000000000000005576 177.0
TLS2_k127_2562105_0 hydrolase, family 3 K05349 - 3.2.1.21 2.022e-265 872.0
TLS2_k127_2562105_1 synthase K00697,K16055 GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 2.154e-202 649.0
TLS2_k127_2562105_10 - - - - 0.000001115 56.0
TLS2_k127_2562105_2 penicillin-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 595.0
TLS2_k127_2562105_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 495.0
TLS2_k127_2562105_4 pfam nlp p60 - - - 0.00000000000000000000000000000000002947 137.0
TLS2_k127_2562105_5 PIN domain - - - 0.0000000000000000000000004835 113.0
TLS2_k127_2562105_6 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000006239 108.0
TLS2_k127_2562105_7 - - - - 0.00000000000000000001044 100.0
TLS2_k127_2562105_8 - - - - 0.000000000000002859 78.0
TLS2_k127_2562105_9 RHS repeat-associated core domain protein - - - 0.0000000002624 66.0
TLS2_k127_2604260_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 1.243e-256 797.0
TLS2_k127_2604260_1 Na H antiporter K03316 - - 2.544e-213 679.0
TLS2_k127_2604260_10 Protein of unknown function (DUF2975) - - - 0.00000000000000000000003382 107.0
TLS2_k127_2604260_11 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000002794 63.0
TLS2_k127_2604260_2 Belongs to the EPSP synthase family. MurA subfamily K00790 GO:0008150,GO:0040007 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 617.0
TLS2_k127_2604260_3 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003924 280.0
TLS2_k127_2604260_4 Protein of unknown function (DUF2550) - - - 0.0000000000000000000000000000000000000001793 155.0
TLS2_k127_2604260_5 - - - - 0.00000000000000000000000000000004708 129.0
TLS2_k127_2604260_6 transcriptional regulator K07727 - - 0.00000000000000000000000000000009795 132.0
TLS2_k127_2604260_7 Methylmalonyl-CoA mutase large subunit K14447 - 5.4.99.63 0.000000000000000000000000000002291 121.0
TLS2_k127_2604260_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000004045 114.0
TLS2_k127_2604260_9 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000001431 106.0
TLS2_k127_2637362_0 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 3.924e-196 621.0
TLS2_k127_2637362_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 600.0
TLS2_k127_2637362_10 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000003528 190.0
TLS2_k127_2637362_11 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000000000000000008282 100.0
TLS2_k127_2637362_12 - - - - 0.0000000000003363 85.0
TLS2_k127_2637362_13 serine threonine protein kinase - - - 0.000000007038 69.0
TLS2_k127_2637362_14 - - - - 0.00009488 55.0
TLS2_k127_2637362_2 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 503.0
TLS2_k127_2637362_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 461.0
TLS2_k127_2637362_4 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 477.0
TLS2_k127_2637362_5 cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 434.0
TLS2_k127_2637362_6 Glycosyl Transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002465 293.0
TLS2_k127_2637362_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003157 284.0
TLS2_k127_2637362_8 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002226 279.0
TLS2_k127_2637362_9 Ion transport protein K10716 GO:0003674,GO:0005215,GO:0005216,GO:0005244,GO:0005249,GO:0005261,GO:0005267,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000009956 209.0
TLS2_k127_2662834_0 Aldehyde dehydrogenase family K22187 - - 4.616e-249 777.0
TLS2_k127_2662834_1 AAA ATPase domain - - - 6.061e-195 615.0
TLS2_k127_2662834_2 Prephenate dehydratase K04518,K14170,K14187 - 1.3.1.12,4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 447.0
TLS2_k127_2662834_3 Major facilitator superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007556 258.0
TLS2_k127_2708497_0 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 2.127e-265 824.0
TLS2_k127_2708497_1 FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 3.036e-261 813.0
TLS2_k127_2708497_2 ABC transporter substrate-binding protein K10546 - - 7.022e-202 636.0
TLS2_k127_2708497_3 Class II Aldolase and Adducin N-terminal domain K03077 - 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 350.0
TLS2_k127_2720244_0 ABC transporter K02056 - 3.6.3.17 3.206e-238 750.0
TLS2_k127_2720244_1 pyrimidine-nucleoside phosphorylase K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 2.853e-225 703.0
TLS2_k127_2720244_10 response regulator - - - 0.00000000000000000000000000000000000000000000000003128 194.0
TLS2_k127_2720244_11 - - - - 0.00000000000000000000000000000000000000001226 163.0
TLS2_k127_2720244_12 Protein of unknown function (DUF3995) - - - 0.00000000000000000000000000237 122.0
TLS2_k127_2720244_13 nuclease - - - 0.0000000000003046 81.0
TLS2_k127_2720244_14 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000004458 61.0
TLS2_k127_2720244_15 Scramblase - - - 0.000004781 58.0
TLS2_k127_2720244_16 Trypsin-like serine protease - - - 0.000006942 59.0
TLS2_k127_2720244_17 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0003225 49.0
TLS2_k127_2720244_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 556.0
TLS2_k127_2720244_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 508.0
TLS2_k127_2720244_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 466.0
TLS2_k127_2720244_5 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 477.0
TLS2_k127_2720244_6 response regulator K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 413.0
TLS2_k127_2720244_7 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 386.0
TLS2_k127_2720244_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000001735 213.0
TLS2_k127_2720244_9 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009972,GO:0009987,GO:0016020,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042455,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.5 0.0000000000000000000000000000000000000000000000000000001199 208.0
TLS2_k127_2727295_0 dead DEAH box helicase K03724 - - 0.0 2297.0
TLS2_k127_2727295_1 peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 525.0
TLS2_k127_2727295_2 Fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 434.0
TLS2_k127_2727295_3 Glycosylase K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 364.0
TLS2_k127_2727295_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 354.0
TLS2_k127_2727295_5 Protein of unknown function (DUF3046) - - - 0.00000000000000001181 99.0
TLS2_k127_2737364_0 Amidohydrolase family - - - 2.638e-241 764.0
TLS2_k127_2737364_1 Transcription regulator of the Arc MetJ class - - - 0.00000000000000000000000000000000000000000000007266 178.0
TLS2_k127_2762123_0 A predicted alpha-helical domain with a conserved ER motif. - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 2.095e-219 712.0
TLS2_k127_2762123_1 synthase K00697,K16055 GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 5.267e-211 682.0
TLS2_k127_2762123_10 NAD-dependent epimerase dehydratase - - - 0.0000000000000001894 81.0
TLS2_k127_2762123_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 596.0
TLS2_k127_2762123_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 437.0
TLS2_k127_2762123_4 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 420.0
TLS2_k127_2762123_5 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 413.0
TLS2_k127_2762123_6 Bacterial transglutaminase-like N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 305.0
TLS2_k127_2762123_7 synthase K00697,K16055 GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000002607 258.0
TLS2_k127_2762123_8 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000007142 128.0
TLS2_k127_2762123_9 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000000006248 82.0
TLS2_k127_2783118_0 Belongs to the carbamoyltransferase HypF family K04656 - - 9.257e-300 950.0
TLS2_k127_2783118_1 PFAM nickel-dependent hydrogenase large subunit K06281 - 1.12.99.6 3.401e-281 871.0
TLS2_k127_2783118_10 PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 304.0
TLS2_k127_2783118_11 membrane K07149 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004362 273.0
TLS2_k127_2783118_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001216 265.0
TLS2_k127_2783118_13 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001311 265.0
TLS2_k127_2783118_14 HNH endonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000004171 228.0
TLS2_k127_2783118_15 Hydrogenase maturation protease - - - 0.0000000000000000000000000000000000000000000000000000000001246 215.0
TLS2_k127_2783118_16 COG0694 Thioredoxin-like proteins and domains - - - 0.0000000000000000000000000000000000000000002385 177.0
TLS2_k127_2783118_17 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000000000000000000000000000000000005158 151.0
TLS2_k127_2783118_18 HupF/HypC family K04653 - - 0.0000000000000000000000000000000001251 136.0
TLS2_k127_2783118_19 - - - - 0.00000000000000000000000000000001255 130.0
TLS2_k127_2783118_2 formation protein HypD K04654 - - 1.058e-206 647.0
TLS2_k127_2783118_20 Protein of unknown function (DUF1641) - - - 0.0000000000000000000003343 102.0
TLS2_k127_2783118_21 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000004908 104.0
TLS2_k127_2783118_22 Hydrogenase nickel incorporation protein hypA K04651 - - 0.00000000000000001716 90.0
TLS2_k127_2783118_23 Amidinotransferase K01478 - 3.5.3.6 0.000001756 53.0
TLS2_k127_2783118_24 response regulator K02488 - 2.7.7.65 0.00009773 55.0
TLS2_k127_2783118_25 - - - - 0.0009015 46.0
TLS2_k127_2783118_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 569.0
TLS2_k127_2783118_4 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 536.0
TLS2_k127_2783118_5 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 492.0
TLS2_k127_2783118_6 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 503.0
TLS2_k127_2783118_7 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 385.0
TLS2_k127_2783118_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 329.0
TLS2_k127_2783118_9 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 310.0
TLS2_k127_2783393_0 PFAM cell divisionFtsK SpoIIIE K03466 GO:0002790,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0020012,GO:0030312,GO:0030682,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0040007,GO:0042783,GO:0042886,GO:0043207,GO:0044110,GO:0044116,GO:0044117,GO:0044315,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136 - 0.0 1699.0
TLS2_k127_2783393_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 7.631e-299 958.0
TLS2_k127_2783393_10 - - - - 0.00000000000000000179 101.0
TLS2_k127_2783393_11 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000006051 78.0
TLS2_k127_2783393_12 domain protein - - - 0.00000000001946 78.0
TLS2_k127_2783393_13 YbaB/EbfC DNA-binding family - - - 0.0000000008855 65.0
TLS2_k127_2783393_15 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000006912 61.0
TLS2_k127_2783393_16 translation initiation factor activity - - - 0.0000003284 67.0
TLS2_k127_2783393_17 - - - - 0.0003185 53.0
TLS2_k127_2783393_18 Excreted virulence factor EspC, type VII ESX diderm - - - 0.0005208 49.0
TLS2_k127_2783393_2 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 334.0
TLS2_k127_2783393_3 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 328.0
TLS2_k127_2783393_4 WXG100 protein secretion system (Wss), protein YukD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004047 266.0
TLS2_k127_2783393_5 type VII secretion protein EccB - - - 0.0000000000000000000000000000000000000000000000000000000000000001822 239.0
TLS2_k127_2783393_6 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000914 136.0
TLS2_k127_2783393_7 PPE family K03110,K03749,K07082,K20276 - - 0.0000000000000000000000000000003106 147.0
TLS2_k127_2783393_8 - - - - 0.00000000000000000000000000001568 138.0
TLS2_k127_2783393_9 translation initiation factor activity K03072,K11717 - 2.8.1.7,4.4.1.16 0.000000000000000001737 100.0
TLS2_k127_2813478_0 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 338.0
TLS2_k127_2813478_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000001067 220.0
TLS2_k127_2813478_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000299 166.0
TLS2_k127_2821214_0 glutamate synthase K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2386.0
TLS2_k127_2821214_1 provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 5.024e-235 736.0
TLS2_k127_2821214_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.008e-224 711.0
TLS2_k127_2821214_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 430.0
TLS2_k127_2821214_4 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 384.0
TLS2_k127_2821214_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 357.0
TLS2_k127_2821214_6 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005747 272.0
TLS2_k127_2827444_0 luxR family - - - 0.0 1257.0
TLS2_k127_2827444_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 558.0
TLS2_k127_2827444_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 530.0
TLS2_k127_2827444_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 439.0
TLS2_k127_2827444_4 Protein of unknown function (DUF3626) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 388.0
TLS2_k127_2827444_5 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 328.0
TLS2_k127_2827444_6 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001236 269.0
TLS2_k127_2827444_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000003513 177.0
TLS2_k127_2827444_8 - - - - 0.000000003794 65.0
TLS2_k127_2845462_0 permease K06901 - - 2.771e-219 692.0
TLS2_k127_2845462_1 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 561.0
TLS2_k127_2845462_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001062 238.0
TLS2_k127_2845462_11 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000005773 229.0
TLS2_k127_2845462_12 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000001579 203.0
TLS2_k127_2845462_13 adenosine 5'-monophosphoramidase activity - - - 0.000000000000000000000000000000000000000000000000000001256 195.0
TLS2_k127_2845462_14 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000008624 181.0
TLS2_k127_2845462_15 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000001868 160.0
TLS2_k127_2845462_16 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000006992 153.0
TLS2_k127_2845462_17 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000006809 135.0
TLS2_k127_2845462_18 PFAM fumarylacetoacetate (FAA) hydrolase K14259 - 4.2.1.141 0.0000000000000000000000000000003959 129.0
TLS2_k127_2845462_19 - - - - 0.0000000000000000000000000000353 131.0
TLS2_k127_2845462_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 467.0
TLS2_k127_2845462_21 histidine kinase HAMP region domain protein K03406 - - 0.0000000004458 63.0
TLS2_k127_2845462_22 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.000001283 58.0
TLS2_k127_2845462_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 452.0
TLS2_k127_2845462_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 426.0
TLS2_k127_2845462_5 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 414.0
TLS2_k127_2845462_6 coenzyme A transferase K01031 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 367.0
TLS2_k127_2845462_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 379.0
TLS2_k127_2845462_8 Coenzyme A transferase K01029,K01032 GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482 2.8.3.5,2.8.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 338.0
TLS2_k127_2845462_9 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008406 268.0
TLS2_k127_285260_0 DNA helicase - - - 2.853e-274 863.0
TLS2_k127_285260_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000002023 215.0
TLS2_k127_285260_2 Protein of unknown function (DUF4031) - - - 0.0000000000000000000000000000000000001474 152.0
TLS2_k127_285260_3 Belongs to the WXG100 family - - - 0.0000000000000000000000000009478 117.0
TLS2_k127_2861366_0 Phosphoglucomutase K01835 - 5.4.2.2 6.126e-201 632.0
TLS2_k127_2861366_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 434.0
TLS2_k127_2861366_2 Serine threonine protein kinase involved in cell cycle control - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 316.0
TLS2_k127_2861366_3 Membrane-bound lytic murein transglycosylase - - - 0.000000000000000000000000000000000000000000000000004324 191.0
TLS2_k127_2861366_4 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000000000000000007645 173.0
TLS2_k127_2880115_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1304.0
TLS2_k127_2880115_1 Fibronectin type III-like domain K05349 - 3.2.1.21 4.232e-313 981.0
TLS2_k127_2880115_10 ComEC Rec2-related protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 329.0
TLS2_k127_2880115_11 nitric oxide dioxygenase activity K05916 - 1.14.12.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 319.0
TLS2_k127_2880115_12 involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004904 260.0
TLS2_k127_2880115_13 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000116 272.0
TLS2_k127_2880115_14 gntR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001758 251.0
TLS2_k127_2880115_15 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000000001122 239.0
TLS2_k127_2880115_16 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000237 205.0
TLS2_k127_2880115_17 diguanylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000001167 208.0
TLS2_k127_2880115_18 - - - - 0.000000000000000000000000000000000000000000000000000003878 194.0
TLS2_k127_2880115_19 Pfam UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000000000000000008418 203.0
TLS2_k127_2880115_2 Aminotransferase class-III K01845 - 5.4.3.8 4.27e-244 761.0
TLS2_k127_2880115_20 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000005998 207.0
TLS2_k127_2880115_21 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000003005 167.0
TLS2_k127_2880115_22 glycosyl transferase family - - - 0.00000000000000000000000000000000000000000000616 184.0
TLS2_k127_2880115_23 COG1555 DNA uptake protein and related DNA-binding K02237 - - 0.0000000000000000000000000000000000000000004471 171.0
TLS2_k127_2880115_24 belongs to the sigma-70 factor family, ECF subfamily - - - 0.000000000000000000000000000000001197 139.0
TLS2_k127_2880115_26 suppressor protein - - - 0.00000000000000000000000000002563 123.0
TLS2_k127_2880115_27 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000003992 120.0
TLS2_k127_2880115_28 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000000000008368 82.0
TLS2_k127_2880115_29 Globin - - - 0.00002146 55.0
TLS2_k127_2880115_3 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 477.0
TLS2_k127_2880115_4 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 474.0
TLS2_k127_2880115_5 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 452.0
TLS2_k127_2880115_6 Aldehyde dehydrogenase family K14519 - 1.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 464.0
TLS2_k127_2880115_7 pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 391.0
TLS2_k127_2880115_8 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 332.0
TLS2_k127_2880115_9 DegV family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 323.0
TLS2_k127_2882657_0 PFAM type III secretion exporter K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 377.0
TLS2_k127_2882657_1 flagellar motor switch protein K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 342.0
TLS2_k127_2882657_2 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 324.0
TLS2_k127_2882657_3 Flagellar motor switch protein FliN K02417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 311.0
TLS2_k127_2882657_4 flagellar biosynthetic protein FliR K02421 - - 0.0000000000000000000000000000000000000000000000000000000000008135 221.0
TLS2_k127_2882657_5 bacterial-type flagellum assembly K02420 - - 0.0000000000000000000000000002965 116.0
TLS2_k127_2882657_7 NAD-dependent epimerase dehydratase - - - 0.0000102 49.0
TLS2_k127_2887135_0 - - - - 1.431e-211 666.0
TLS2_k127_2887135_1 Aminotransferase K01845 - 5.4.3.8 2.061e-201 638.0
TLS2_k127_2887135_10 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 339.0
TLS2_k127_2887135_11 Cytochrome c biogenesis protein K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 319.0
TLS2_k127_2887135_12 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 317.0
TLS2_k127_2887135_13 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008706 227.0
TLS2_k127_2887135_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000002548 215.0
TLS2_k127_2887135_15 Alkyl hydroperoxide reductase Thiol specific antioxidant - - - 0.00000000000000000000000000000000000000000009763 171.0
TLS2_k127_2887135_16 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000007805 91.0
TLS2_k127_2887135_17 Phospholipase_D-nuclease N-terminal - - - 0.00000000001621 74.0
TLS2_k127_2887135_18 Protein of unknown function (DUF4229) - - - 0.0004736 48.0
TLS2_k127_2887135_2 Isochorismate synthase K02552 - 5.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 553.0
TLS2_k127_2887135_3 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 553.0
TLS2_k127_2887135_4 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 533.0
TLS2_k127_2887135_5 ResB protein required for cytochrome c biosynthesis K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 536.0
TLS2_k127_2887135_6 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 431.0
TLS2_k127_2887135_7 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01911,K02549 GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007 4.2.1.113,6.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 402.0
TLS2_k127_2887135_8 cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 383.0
TLS2_k127_2887135_9 Belongs to the MenA family. Type 1 subfamily K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 357.0
TLS2_k127_2910264_0 c reductase K03890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 465.0
TLS2_k127_2910264_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 426.0
TLS2_k127_2910264_2 cytochrome c oxidase, subunit III K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 349.0
TLS2_k127_2910264_3 Cytochrome c K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 326.0
TLS2_k127_2910264_4 Cytochrome b K03891 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000008424 231.0
TLS2_k127_2910264_5 response regulator - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000001965 190.0
TLS2_k127_2941603_0 carboxylase K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 3.699e-308 952.0
TLS2_k127_2941603_1 acetyl-CoA hydrolase K18118 - 2.8.3.18 1.187e-274 860.0
TLS2_k127_2941603_10 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005271 265.0
TLS2_k127_2941603_11 interspecies interaction between organisms - - - 0.00000000000000000000000000000000000000000000000000001202 213.0
TLS2_k127_2941603_12 Thioredoxin K00384,K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000002296 190.0
TLS2_k127_2941603_13 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000003627 179.0
TLS2_k127_2941603_14 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000005358 170.0
TLS2_k127_2941603_15 MerR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000007061 169.0
TLS2_k127_2941603_16 distant relative of homeotic protein bithoraxoid K07131 - - 0.000000000000001969 86.0
TLS2_k127_2941603_17 Family of unknown function (DUF5302) - - - 0.00007035 49.0
TLS2_k127_2941603_2 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit K01962,K01963 - 2.1.3.15,6.4.1.2 4.799e-208 661.0
TLS2_k127_2941603_3 Bacterial protein of unknown function (DUF885) - - - 9.243e-194 620.0
TLS2_k127_2941603_4 Acyl-CoA dehydrogenase, C-terminal domain K00248,K11410 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 533.0
TLS2_k127_2941603_5 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 497.0
TLS2_k127_2941603_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 424.0
TLS2_k127_2941603_7 TIGRFAM Drug resistance transporter Bcr CflA subfamily K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 383.0
TLS2_k127_2941603_8 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 311.0
TLS2_k127_2941603_9 Maf-like protein K06287 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 280.0
TLS2_k127_2981725_0 Aminotransferase class-III K00596 - 4.1.1.64 5.679e-194 613.0
TLS2_k127_2981725_1 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 531.0
TLS2_k127_2981725_2 Amb_all K01728 - 4.2.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 320.0
TLS2_k127_2981725_3 His Kinase A (phosphoacceptor) domain K02484 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0046983,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 0.000000000000000000003918 94.0
TLS2_k127_2997202_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 1.066e-214 691.0
TLS2_k127_2997202_1 ThiF family K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 531.0
TLS2_k127_2997202_10 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001819 285.0
TLS2_k127_2997202_11 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001271 266.0
TLS2_k127_2997202_12 Protein of unknown function (DUF3152) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004302 256.0
TLS2_k127_2997202_13 UPF0056 membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000002347 241.0
TLS2_k127_2997202_14 - - - - 0.0000000000000000000000000000000000000000000000000000000002577 217.0
TLS2_k127_2997202_15 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000005193 215.0
TLS2_k127_2997202_16 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000002035 185.0
TLS2_k127_2997202_17 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000002111 175.0
TLS2_k127_2997202_18 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000000000005353 158.0
TLS2_k127_2997202_19 ATP-binding protein - - - 0.000000000000000000001211 96.0
TLS2_k127_2997202_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 377.0
TLS2_k127_2997202_20 - - - - 0.000000000000000000006134 104.0
TLS2_k127_2997202_21 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000002716 95.0
TLS2_k127_2997202_3 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 355.0
TLS2_k127_2997202_4 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 328.0
TLS2_k127_2997202_5 SMART phosphoesterase PHP domain protein K07053,K20859 - 3.1.3.97,3.1.4.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 330.0
TLS2_k127_2997202_6 Plasmid partitioning protein ParA K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 326.0
TLS2_k127_2997202_7 PD-(D/E)XK nuclease superfamily K07465 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 323.0
TLS2_k127_2997202_8 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 337.0
TLS2_k127_2997202_9 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002995 306.0
TLS2_k127_3040621_0 Peptidase family M13 K01389,K01415,K07386 - 3.4.24.11,3.4.24.71 1.689e-283 884.0
TLS2_k127_3040621_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 8.734e-237 759.0
TLS2_k127_3040621_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000251 244.0
TLS2_k127_3040621_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000005471 241.0
TLS2_k127_3040621_12 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000121 154.0
TLS2_k127_3040621_13 RNA polymerase sigma-24 subunit, ECF subfamily - - - 0.000000000000000000000000000000000001313 155.0
TLS2_k127_3040621_2 lacI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 464.0
TLS2_k127_3040621_3 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 369.0
TLS2_k127_3040621_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 370.0
TLS2_k127_3040621_5 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001343 291.0
TLS2_k127_3040621_6 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001377 278.0
TLS2_k127_3040621_7 Belongs to the ribulokinase family K00853 - 2.7.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000001006 257.0
TLS2_k127_3040621_8 Lycopene cyclase protein K06443 - 5.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000004093 263.0
TLS2_k127_3040621_9 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0071704,GO:0090407,GO:1901576 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000001798 244.0
TLS2_k127_3043153_0 chemotaxis protein K03407 - 2.7.13.3 3.2e-207 674.0
TLS2_k127_3043153_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 607.0
TLS2_k127_3043153_10 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000002705 179.0
TLS2_k127_3043153_11 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000702 160.0
TLS2_k127_3043153_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000503 135.0
TLS2_k127_3043153_13 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000000002058 115.0
TLS2_k127_3043153_14 transferase activity, transferring glycosyl groups K19002 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 0.000000000000000000000002182 118.0
TLS2_k127_3043153_15 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000003383 109.0
TLS2_k127_3043153_16 PTS system, Lactose/Cellobiose specific IIB subunit K02768,K02769,K02770 - 2.7.1.202 0.000000000001005 69.0
TLS2_k127_3043153_17 - - - - 0.0000000004471 67.0
TLS2_k127_3043153_18 PFAM Sulphate transporter antisigma-factor antagonist STAS - - - 0.00000000163 66.0
TLS2_k127_3043153_19 SMART CheW-like protein K03408 - - 0.0002299 47.0
TLS2_k127_3043153_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 469.0
TLS2_k127_3043153_3 SAICAR synthetase K01923,K01945 - 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 458.0
TLS2_k127_3043153_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0001666,GO:0006950,GO:0008150,GO:0009415,GO:0009628,GO:0010035,GO:0036293,GO:0042221,GO:0050896,GO:0070482,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 436.0
TLS2_k127_3043153_5 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000856 284.0
TLS2_k127_3043153_6 PFAM Chemotaxis methyl-accepting receptor, signalling K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003499 261.0
TLS2_k127_3043153_7 SMART Signal transduction response regulator, receiver region K03413 - - 0.0000000000000000000000000000000000000000000000000000000003296 203.0
TLS2_k127_3043153_8 - - - - 0.000000000000000000000000000000000000000000000000000001545 205.0
TLS2_k127_3043153_9 - - - - 0.00000000000000000000000000000000000000000000000001246 198.0
TLS2_k127_3043452_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097 5.99.1.3 0.0 1366.0
TLS2_k127_3043452_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 0.0 1031.0
TLS2_k127_3043452_10 Transmembrane domain of unknown function (DUF3566) - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000003425 139.0
TLS2_k127_3043452_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000005066 125.0
TLS2_k127_3043452_12 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0008150,GO:0040007 3.1.26.5 0.000000000000000000000004374 108.0
TLS2_k127_3043452_13 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000001357 88.0
TLS2_k127_3043452_14 Transposase, mutator K07493 - - 0.000000000000004009 80.0
TLS2_k127_3043452_15 transposase IS116 IS110 IS902 family - - - 0.000000002647 64.0
TLS2_k127_3043452_16 - - - - 0.000000007581 59.0
TLS2_k127_3043452_17 - - - - 0.0004293 46.0
TLS2_k127_3043452_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 1.304e-207 663.0
TLS2_k127_3043452_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 583.0
TLS2_k127_3043452_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 516.0
TLS2_k127_3043452_5 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 473.0
TLS2_k127_3043452_6 Preprotein translocase subunit YidC K03217 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 418.0
TLS2_k127_3043452_7 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000001538 246.0
TLS2_k127_3043452_8 R3H domain protein K06346 - - 0.000000000000000000000000000000000000000000000000000000000002181 219.0
TLS2_k127_3043452_9 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000000000000000000000000000000000000000000008482 195.0
TLS2_k127_311372_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.391e-291 906.0
TLS2_k127_311372_1 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007381 282.0
TLS2_k127_311372_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001321 235.0
TLS2_k127_311372_3 - - - - 0.000000000000000000000000000003088 129.0
TLS2_k127_3117196_0 Domain of unknown function (DUF4082) - - - 0.0 1305.0
TLS2_k127_3117196_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 416.0
TLS2_k127_3117196_10 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family - - - 0.00000000000000000000000000000000000000000000000000000000000000004533 230.0
TLS2_k127_3117196_11 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000001697 189.0
TLS2_k127_3117196_12 Glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000185 148.0
TLS2_k127_3117196_13 Formyl transferase, C-terminal domain - - - 0.0000000000000000000003366 107.0
TLS2_k127_3117196_2 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 406.0
TLS2_k127_3117196_3 transferase activity, transferring glycosyl groups K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 380.0
TLS2_k127_3117196_4 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 359.0
TLS2_k127_3117196_5 PFAM oxidoreductase domain protein K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 341.0
TLS2_k127_3117196_6 PFAM O-antigen polymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 299.0
TLS2_k127_3117196_7 Polysaccharide biosynthesis protein K03328,K16695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001483 297.0
TLS2_k127_3117196_8 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004186 282.0
TLS2_k127_3117196_9 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002073 261.0
TLS2_k127_3133892_0 SWIM zinc finger - - - 1.089e-264 862.0
TLS2_k127_3133892_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 509.0
TLS2_k127_3133892_10 - - - - 0.000000000000000000000000000000000000000000000001555 183.0
TLS2_k127_3133892_11 - - - - 0.0000000000000000000000000000000000000000005879 164.0
TLS2_k127_3133892_12 Helix-turn-helix domain K07729 - - 0.0000000000000000000000000000001253 127.0
TLS2_k127_3133892_13 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.0000000181 55.0
TLS2_k127_3133892_14 Ribosomal protein L7/L12 C-terminal domain - - - 0.0005558 48.0
TLS2_k127_3133892_2 Dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 398.0
TLS2_k127_3133892_3 polyphosphate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 397.0
TLS2_k127_3133892_4 ribulose-bisphosphate carboxylase activity K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 379.0
TLS2_k127_3133892_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 371.0
TLS2_k127_3133892_6 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 292.0
TLS2_k127_3133892_7 Pterin binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 299.0
TLS2_k127_3133892_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000741 208.0
TLS2_k127_3133892_9 RibD C-terminal domain K00082 - 1.1.1.193 0.00000000000000000000000000000000000000000000000000000004083 206.0
TLS2_k127_3142837_0 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 9.853e-252 778.0
TLS2_k127_3142837_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003648 243.0
TLS2_k127_3142837_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000004747 140.0
TLS2_k127_3142837_3 - - - - 0.00000000000000003355 94.0
TLS2_k127_3142837_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.0000000000002048 71.0
TLS2_k127_316340_0 - - - - 3.46e-196 638.0
TLS2_k127_316340_1 Suppressor of fused protein (SUFU) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001216 284.0
TLS2_k127_316340_3 - - - - 0.000000000000000000000000000001512 126.0
TLS2_k127_3184686_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 591.0
TLS2_k127_3184686_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 464.0
TLS2_k127_3184686_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 417.0
TLS2_k127_3184686_3 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 338.0
TLS2_k127_3184686_4 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 323.0
TLS2_k127_3184686_5 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000001808 161.0
TLS2_k127_3184686_6 Lanthionine synthetase C family protein - - - 0.000000000000000000000000000002733 130.0
TLS2_k127_3250267_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 0.0 1544.0
TLS2_k127_3250267_1 helicase K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 7.891e-264 837.0
TLS2_k127_3250267_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 370.0
TLS2_k127_3250267_3 sigma factor antagonist activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002911 298.0
TLS2_k127_3250267_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001004 262.0
TLS2_k127_3250267_5 LysM domain - - - 0.00000000000000001423 91.0
TLS2_k127_3261372_0 Cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 583.0
TLS2_k127_3261372_1 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 558.0
TLS2_k127_3261372_10 - - - - 0.00000004449 59.0
TLS2_k127_3261372_2 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 454.0
TLS2_k127_3261372_3 allophanate hydrolase subunit 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 350.0
TLS2_k127_3261372_4 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 347.0
TLS2_k127_3261372_5 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 321.0
TLS2_k127_3261372_6 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 310.0
TLS2_k127_3261372_7 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003643 279.0
TLS2_k127_3261372_8 Cyclic nucleotide-monophosphate binding domain K01420 - - 0.0000000000000000000000000000000000003095 149.0
TLS2_k127_3261372_9 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000001134 119.0
TLS2_k127_3336869_0 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 545.0
TLS2_k127_3336869_1 PFAM Phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 297.0
TLS2_k127_3336869_2 Sigma-70, region 4 K03088 GO:0000988,GO:0000990,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000004745 205.0
TLS2_k127_3336869_3 PFAM Rieske 2Fe-2S - - - 0.000000000000000000000000000007326 126.0
TLS2_k127_3336869_4 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000001125 121.0
TLS2_k127_3336869_5 AntiSigma factor - - - 0.00000000004183 74.0
TLS2_k127_3356740_0 GGDEF domain - - - 0.0 1200.0
TLS2_k127_3356740_1 Glycosyl hydrolase family 62 K01181 - 3.2.1.8 8.69e-316 987.0
TLS2_k127_3356740_2 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 412.0
TLS2_k127_337814_0 transcriptional regulator K13653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 496.0
TLS2_k127_337814_1 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 510.0
TLS2_k127_337814_11 - - - - 0.0000000000000000000001172 104.0
TLS2_k127_337814_13 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000000000345 86.0
TLS2_k127_337814_14 Alpha/beta-hydrolase family N-terminus - - - 0.0000000846 56.0
TLS2_k127_337814_15 heme oxygenase - - - 0.00002406 56.0
TLS2_k127_337814_16 Alpha/beta-hydrolase family N-terminus - - - 0.00004651 54.0
TLS2_k127_337814_2 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 335.0
TLS2_k127_337814_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001497 277.0
TLS2_k127_337814_4 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006338 259.0
TLS2_k127_337814_5 phage tail protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004589 246.0
TLS2_k127_337814_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000005961 235.0
TLS2_k127_337814_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000002442 200.0
TLS2_k127_337814_8 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000001066 184.0
TLS2_k127_337814_9 YjbR - - - 0.000000000000000000000000000000591 136.0
TLS2_k127_338187_0 Type IV secretion-system coupling protein DNA-binding domain K06915 - - 8.73e-211 704.0
TLS2_k127_338187_1 uroporphyrin-III c-methyltransferase K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 403.0
TLS2_k127_338187_10 Gcn5-related n-acetyltransferase - - - 0.00000000000000000000000000000000002872 142.0
TLS2_k127_338187_11 YCII-related domain - - - 0.0000000000000000000000000000000932 144.0
TLS2_k127_338187_12 Type VII secretion protein - - - 0.000000000000000001363 101.0
TLS2_k127_338187_13 transferase activity, transferring glycosyl groups - - - 0.0000000000007516 79.0
TLS2_k127_338187_14 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000008144 71.0
TLS2_k127_338187_15 Sigma-70 region 2 K03088 - - 0.0000133 54.0
TLS2_k127_338187_2 DNA segregation ATPase FtsK SpoIIIE and related K03466 GO:0002790,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0020012,GO:0030312,GO:0030682,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0040007,GO:0042783,GO:0042886,GO:0043207,GO:0044110,GO:0044116,GO:0044117,GO:0044315,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 351.0
TLS2_k127_338187_3 Type VII secretion system ESX-1, transport TM domain B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 304.0
TLS2_k127_338187_4 Pfam Cation efflux - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000125 284.0
TLS2_k127_338187_5 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000001021 221.0
TLS2_k127_338187_6 WXG100 protein secretion system (Wss), protein YukD - - - 0.000000000000000000000000000000000000000000000000000006356 208.0
TLS2_k127_338187_7 NUDIX domain - - - 0.000000000000000000000000000000000000000007237 161.0
TLS2_k127_338187_8 Homeodomain-like domain - - - 0.00000000000000000000000000000000000000001734 167.0
TLS2_k127_338187_9 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000007137 154.0
TLS2_k127_3385311_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 1.141e-199 629.0
TLS2_k127_3385311_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 586.0
TLS2_k127_3385311_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001153 263.0
TLS2_k127_3385311_3 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003618 263.0
TLS2_k127_3385311_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000001824 229.0
TLS2_k127_3385311_5 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000009891 166.0
TLS2_k127_3390455_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 441.0
TLS2_k127_3390455_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 434.0
TLS2_k127_3390455_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002921 267.0
TLS2_k127_3390455_3 Cell wall assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000005326 239.0
TLS2_k127_3390455_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000001096 192.0
TLS2_k127_3390455_5 pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000000000000000000000001297 189.0
TLS2_k127_3390455_6 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000345 94.0
TLS2_k127_3390455_7 lyase activity - - - 0.0000000000001017 81.0
TLS2_k127_3390455_8 - - - - 0.000683 47.0
TLS2_k127_3397460_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657 3.3.1.1 6.615e-264 822.0
TLS2_k127_3397460_1 Transcriptional regulator K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008538 560.0
TLS2_k127_3397460_2 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 447.0
TLS2_k127_3397460_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 306.0
TLS2_k127_3397460_4 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005464 270.0
TLS2_k127_3397460_5 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004888 246.0
TLS2_k127_3397460_6 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000009953 197.0
TLS2_k127_3397460_7 - - - - 0.0000000000000000000000000001406 116.0
TLS2_k127_3397460_8 tetraacyldisaccharide 4'-kinase activity K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.00000000000000000000007398 104.0
TLS2_k127_3397460_9 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000002352 93.0
TLS2_k127_3399076_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.0 1193.0
TLS2_k127_3399076_1 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005988 268.0
TLS2_k127_3399076_2 - - - - 0.00000000000000000000000000000002401 130.0
TLS2_k127_3400381_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 1.357e-239 761.0
TLS2_k127_3400381_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 592.0
TLS2_k127_3400381_2 sulfurtransferase K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 494.0
TLS2_k127_3400381_3 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 439.0
TLS2_k127_3400381_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 421.0
TLS2_k127_3400381_5 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 366.0
TLS2_k127_3400381_6 PaaX-like protein K02616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 305.0
TLS2_k127_3400381_7 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000001593 240.0
TLS2_k127_3400381_8 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000479 185.0
TLS2_k127_3486237_0 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335,K05587 - 1.6.5.3 5.271e-198 640.0
TLS2_k127_3486237_1 Coenzyme F420-reducing hydrogenase, alpha subunit K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 571.0
TLS2_k127_3486237_2 Orn/Lys/Arg decarboxylase, C-terminal domain K01585 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 547.0
TLS2_k127_3486237_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K05588 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000564 298.0
TLS2_k127_3486237_4 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000001162 205.0
TLS2_k127_3486237_5 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000001098 175.0
TLS2_k127_3505736_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366,K00392 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.7.7.1,1.8.7.1 6.558e-267 839.0
TLS2_k127_3505736_1 type II secretion system protein E K02652 - - 1.319e-223 735.0
TLS2_k127_3505736_10 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001272 245.0
TLS2_k127_3505736_11 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000003952 226.0
TLS2_k127_3505736_12 - - - - 0.00000000000000000000000000000000000000000000000000000000007052 221.0
TLS2_k127_3505736_13 - - - - 0.000000000000000000000000000000000000000000000000008466 189.0
TLS2_k127_3505736_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000001085 188.0
TLS2_k127_3505736_15 LysE type translocator - - - 0.00000000000000000000000000000000000000000004556 181.0
TLS2_k127_3505736_16 protein secretion K03116,K03117 - - 0.0000000000000000000000000000000000000002435 154.0
TLS2_k127_3505736_17 - - - - 0.0000000000000000339 96.0
TLS2_k127_3505736_18 rRNA binding - - - 0.00000000001472 70.0
TLS2_k127_3505736_19 oxidoreductase activity - - - 0.00000000002187 77.0
TLS2_k127_3505736_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 3.768e-217 694.0
TLS2_k127_3505736_20 - - - - 0.0000000619 65.0
TLS2_k127_3505736_21 Repeat of unknown function (DUF346) - - - 0.000001329 60.0
TLS2_k127_3505736_3 Belongs to the HpcH HpaI aldolase family K01644,K14447 - 4.1.3.34,5.4.99.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 553.0
TLS2_k127_3505736_4 transporter mgtE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 546.0
TLS2_k127_3505736_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 545.0
TLS2_k127_3505736_6 Peptidase s1 and s6 chymotrypsin hap K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 406.0
TLS2_k127_3505736_7 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 353.0
TLS2_k127_3505736_8 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001102 267.0
TLS2_k127_3505736_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001175 249.0
TLS2_k127_3510626_0 PFAM glycoside hydrolase family 65 central catalytic - - - 0.0 1065.0
TLS2_k127_3510626_1 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 3.56e-322 1013.0
TLS2_k127_3510626_10 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 419.0
TLS2_k127_3510626_11 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 411.0
TLS2_k127_3510626_12 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 399.0
TLS2_k127_3510626_13 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 383.0
TLS2_k127_3510626_14 PFAM ADP-ribosylation Crystallin J1 K05521 - 3.2.2.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 387.0
TLS2_k127_3510626_15 Acetoacetate decarboxylase (ADC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 353.0
TLS2_k127_3510626_16 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 333.0
TLS2_k127_3510626_17 Rieske [2Fe-2S] domain K19982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 321.0
TLS2_k127_3510626_18 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 309.0
TLS2_k127_3510626_19 HNH endonuclease K07454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 294.0
TLS2_k127_3510626_2 helix_turn_helix, Lux Regulon - - - 5.356e-321 1008.0
TLS2_k127_3510626_20 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001763 286.0
TLS2_k127_3510626_22 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005049 265.0
TLS2_k127_3510626_23 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
TLS2_k127_3510626_24 protein conserved in bacteria K09935 - - 0.0000000000000000000000000000000000000000000000000000000000000000001297 235.0
TLS2_k127_3510626_25 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000001608 238.0
TLS2_k127_3510626_26 protein secretion by the type IV secretion system - - - 0.0000000000000000000000000000000000000000000000000000000003563 214.0
TLS2_k127_3510626_27 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000000000000002195 209.0
TLS2_k127_3510626_28 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000007361 161.0
TLS2_k127_3510626_29 Hemerythrin HHE cation binding - - - 0.0000000000000000000000000000000000000001166 163.0
TLS2_k127_3510626_3 Belongs to the aldehyde dehydrogenase family K00130,K00151 - 1.2.1.60,1.2.1.8 1.961e-222 699.0
TLS2_k127_3510626_30 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001363 156.0
TLS2_k127_3510626_31 transcriptional regulator - - - 0.000000000000000000000000000000004978 135.0
TLS2_k127_3510626_32 - - - - 0.00000000000000000000000000000000532 140.0
TLS2_k127_3510626_33 - - - - 0.0000000000000000000000000000000663 141.0
TLS2_k127_3510626_34 lyase activity - - - 0.00000000000000000000000004325 120.0
TLS2_k127_3510626_35 - - - - 0.000000000000000000000003009 107.0
TLS2_k127_3510626_36 Glutamine amidotransferase class-I - - - 0.0000000000000000000003344 102.0
TLS2_k127_3510626_38 - - - - 0.00000000000000000001154 95.0
TLS2_k127_3510626_39 - - - - 0.000000000000000003097 91.0
TLS2_k127_3510626_4 Belongs to the aldehyde dehydrogenase family K09472 - 1.2.1.99 4.831e-206 657.0
TLS2_k127_3510626_40 HEPN domain - - - 0.0000000000000002168 81.0
TLS2_k127_3510626_41 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000004295 78.0
TLS2_k127_3510626_43 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000000000003143 81.0
TLS2_k127_3510626_44 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000002014 68.0
TLS2_k127_3510626_45 - - - - 0.00000000005928 70.0
TLS2_k127_3510626_46 lactoylglutathione lyase activity - - - 0.0000000002297 66.0
TLS2_k127_3510626_48 lactoylglutathione lyase activity - - - 0.0002769 49.0
TLS2_k127_3510626_5 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 616.0
TLS2_k127_3510626_6 cytochrome P-450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 553.0
TLS2_k127_3510626_7 Aldolase/RraA K05921 - 4.1.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 529.0
TLS2_k127_3510626_8 L-fucose H symporter permease K02429 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 535.0
TLS2_k127_3510626_9 Bacterial extracellular solute-binding protein K17315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 428.0
TLS2_k127_3512010_0 sugar transferase - - - 1.733e-201 640.0
TLS2_k127_3512010_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 3.056e-200 636.0
TLS2_k127_3512010_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 555.0
TLS2_k127_3512010_3 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 472.0
TLS2_k127_3512010_4 Molecular chaperone. Has ATPase activity K04079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 349.0
TLS2_k127_3512010_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 321.0
TLS2_k127_3512010_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000009175 245.0
TLS2_k127_3512010_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001816 241.0
TLS2_k127_3512010_8 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002391 233.0
TLS2_k127_3512010_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000007349 257.0
TLS2_k127_3512496_0 DNA helicase K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0 1163.0
TLS2_k127_3512496_1 UDP-galactopyranose mutase K01854 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 7.294e-200 627.0
TLS2_k127_3512496_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 394.0
TLS2_k127_3512496_3 with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 338.0
TLS2_k127_3512496_4 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 312.0
TLS2_k127_3512496_5 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000002515 222.0
TLS2_k127_3512496_6 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000006825 203.0
TLS2_k127_3512496_7 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000001247 167.0
TLS2_k127_3512496_8 - - - - 0.00000000000000000000000000000000001191 147.0
TLS2_k127_3512496_9 xylan catabolic process K03932,K21105 - 3.1.1.102 0.000000000000009448 85.0
TLS2_k127_35133_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 8.062e-206 646.0
TLS2_k127_35133_1 arginine K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 521.0
TLS2_k127_35133_10 Domain of unknown function (DUF4307) - - - 0.000000000001459 74.0
TLS2_k127_35133_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 507.0
TLS2_k127_35133_3 MutL protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 494.0
TLS2_k127_35133_4 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics K18455 GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657 3.5.1.115 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 434.0
TLS2_k127_35133_5 GMC oxidoreductase K00108 - 1.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 392.0
TLS2_k127_35133_6 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 348.0
TLS2_k127_35133_7 chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 350.0
TLS2_k127_35133_8 permease K20469 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 338.0
TLS2_k127_35133_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000003124 232.0
TLS2_k127_3522797_0 Cation transporting ATPase, C-terminus K01537 - 3.6.3.8 0.0 1128.0
TLS2_k127_3522797_1 Transposase - - - 0.00000000000000000000000000000000000000000007067 163.0
TLS2_k127_3522797_2 - - - - 0.000000000000000000000000000000001268 134.0
TLS2_k127_3522797_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000001447 103.0
TLS2_k127_3522797_4 PIN domain - - - 0.000000000001598 69.0
TLS2_k127_3522797_5 self proteolysis - - - 0.000000000001598 69.0
TLS2_k127_3532114_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1139.0
TLS2_k127_3532114_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.341e-270 859.0
TLS2_k127_3532114_10 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 372.0
TLS2_k127_3532114_11 Diacylglycerol kinase K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 349.0
TLS2_k127_3532114_12 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 339.0
TLS2_k127_3532114_13 hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 321.0
TLS2_k127_3532114_14 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 301.0
TLS2_k127_3532114_15 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002376 286.0
TLS2_k127_3532114_16 Fructosamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001155 275.0
TLS2_k127_3532114_17 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000021 270.0
TLS2_k127_3532114_18 SMART helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001447 221.0
TLS2_k127_3532114_19 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000002098 227.0
TLS2_k127_3532114_2 Adenylosuccinate lyase K01756 - 4.3.2.2 1.289e-231 728.0
TLS2_k127_3532114_20 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000002808 200.0
TLS2_k127_3532114_21 polysaccharide deacetylase K01181,K22278 - 3.2.1.8,3.5.1.104 0.00000000000000000000000000000000000000000000007177 184.0
TLS2_k127_3532114_22 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000001025 189.0
TLS2_k127_3532114_23 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000000000000000000000007372 160.0
TLS2_k127_3532114_24 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000002546 149.0
TLS2_k127_3532114_25 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000001639 132.0
TLS2_k127_3532114_26 transcriptional regulators - - - 0.0000000000000000000000000005867 131.0
TLS2_k127_3532114_27 membrane K08972 - - 0.000000000000000000000000005103 122.0
TLS2_k127_3532114_28 isochorismatase hydrolase - - - 0.00000000000000000000001592 103.0
TLS2_k127_3532114_29 Heavy-metal-associated domain - - - 0.00000000000000000000146 96.0
TLS2_k127_3532114_3 PFAM cell divisionFtsK SpoIIIE - - - 1.123e-219 720.0
TLS2_k127_3532114_30 Protein of unknown function (DUF2630) - - - 0.00000000000000009559 82.0
TLS2_k127_3532114_32 Domain of unknown function (DUF397) - - - 0.0000000000002048 74.0
TLS2_k127_3532114_33 helix_turn_helix, mercury resistance K08365 - - 0.000000000001988 74.0
TLS2_k127_3532114_34 - - - - 0.000005633 60.0
TLS2_k127_3532114_35 transmembrane signaling receptor activity K03406 - - 0.0005305 48.0
TLS2_k127_3532114_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 1.542e-198 628.0
TLS2_k127_3532114_5 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 590.0
TLS2_k127_3532114_6 Proline racemase K01777 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 542.0
TLS2_k127_3532114_7 Alanine dehydrogenase/PNT, C-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 503.0
TLS2_k127_3532114_8 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 467.0
TLS2_k127_3532114_9 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 410.0
TLS2_k127_3549826_0 Transposase DDE domain group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 571.0
TLS2_k127_3549826_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 547.0
TLS2_k127_3549826_10 lyase activity - - - 0.00000000001037 68.0
TLS2_k127_3549826_2 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 517.0
TLS2_k127_3549826_3 FAD binding domain K14672,K15972 - 1.14.13.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 406.0
TLS2_k127_3549826_4 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 344.0
TLS2_k127_3549826_5 PIN domain - - - 0.0000000000000000000000000000000000000000000000003633 178.0
TLS2_k127_3549826_6 protein conserved in bacteria - - - 0.000000000000000000000000001373 119.0
TLS2_k127_3549826_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000007451 85.0
TLS2_k127_3549826_8 HEPN domain - - - 0.00000000000000005941 86.0
TLS2_k127_3595827_0 PFAM FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 1.916e-208 658.0
TLS2_k127_3595827_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 494.0
TLS2_k127_3595827_2 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 435.0
TLS2_k127_3595827_3 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000005271 83.0
TLS2_k127_3596444_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 4.907e-274 852.0
TLS2_k127_3596444_1 Ribokinase K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 464.0
TLS2_k127_3596444_2 Belongs to the glycerate kinase type-1 family K00865 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 390.0
TLS2_k127_3596444_3 I and II form the functional core of the enzyme complex. electrons originating in cytochrome C are transferred via HemE a and cu(a) to the binuclear center formed by HemE A3 and cu(B) K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 370.0
TLS2_k127_3596444_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 342.0
TLS2_k127_3596444_5 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007759 245.0
TLS2_k127_3596444_6 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000001888 217.0
TLS2_k127_3596444_7 Belongs to the cytochrome c oxidase bacterial subunit CtaF family - - - 0.00000000000000000000000000000000000001202 148.0
TLS2_k127_3608787_0 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 3.099e-276 856.0
TLS2_k127_3608787_1 Na H antiporter K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 572.0
TLS2_k127_3608787_2 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 420.0
TLS2_k127_3608787_3 RDD family - - - 0.000000000000000000000000000000000000000003076 159.0
TLS2_k127_3626468_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.4.4.2 0.0 1414.0
TLS2_k127_3626468_1 glutamate--cysteine ligase - - - 2.355e-237 745.0
TLS2_k127_3626468_10 (FHA) domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.000000000000000000000000000000000000000000000000000006439 200.0
TLS2_k127_3626468_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000001192 189.0
TLS2_k127_3626468_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 6.488e-237 747.0
TLS2_k127_3626468_3 Exonuclease K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 591.0
TLS2_k127_3626468_4 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 470.0
TLS2_k127_3626468_5 chromosome partitioning - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 321.0
TLS2_k127_3626468_6 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 310.0
TLS2_k127_3626468_7 helix_turn_helix, mercury resistance - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
TLS2_k127_3626468_8 PFAM Uncharacterised ACR, COG1259 K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002525 256.0
TLS2_k127_3626468_9 protein conserved in bacteria - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000004619 222.0
TLS2_k127_3638766_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 391.0
TLS2_k127_3638766_1 Protein of unknown function (DUF501) K09009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004062 243.0
TLS2_k127_3638766_2 Septum formation initiator K13052 - - 0.00000000000000000002043 104.0
TLS2_k127_3638766_3 - - - - 0.00000000000000000327 95.0
TLS2_k127_3638766_4 protein involved in exopolysaccharide biosynthesis - - - 0.000000000008091 76.0
TLS2_k127_3650063_0 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 2.185e-196 618.0
TLS2_k127_3650063_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 542.0
TLS2_k127_3650063_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 497.0
TLS2_k127_3650063_3 Alkane 1-monooxygenase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 448.0
TLS2_k127_3650063_4 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 360.0
TLS2_k127_3650063_5 Alpha beta K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 298.0
TLS2_k127_3650063_6 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000002855 190.0
TLS2_k127_3650063_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000003374 185.0
TLS2_k127_3650063_8 Lsr2 - - - 0.000000000000002137 81.0
TLS2_k127_3654156_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.188e-245 762.0
TLS2_k127_3654156_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.556e-207 662.0
TLS2_k127_3654156_2 PFAM membrane-flanked domain K08981 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 482.0
TLS2_k127_3654156_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 362.0
TLS2_k127_3654156_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 327.0
TLS2_k127_3654156_5 membrane K09167 - - 0.00000000000000000000000000000000000000000000000001915 184.0
TLS2_k127_3654156_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000003768 179.0
TLS2_k127_3654156_7 Protein of unknown function (DUF3180) - - - 0.000000000000000000000000000000000000000009893 159.0
TLS2_k127_3654156_8 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K13940 GO:0008150,GO:0040007 1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000002569 156.0
TLS2_k127_366273_0 transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 449.0
TLS2_k127_366273_1 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 385.0
TLS2_k127_366273_2 Domain of unknown function (DUF4352) - - - 0.0000000000000000000000000000000000000000000000003957 186.0
TLS2_k127_366273_3 Protein of unknown function (DUF4238) - - - 0.00000000000000000000000000000000000007155 156.0
TLS2_k127_366273_4 PFAM Integrase catalytic region K07497 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000003238 120.0
TLS2_k127_3707714_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K07469 - 1.2.99.7 0.0 1267.0
TLS2_k127_3707714_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 579.0
TLS2_k127_3707714_2 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 374.0
TLS2_k127_3707714_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 359.0
TLS2_k127_3707714_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 338.0
TLS2_k127_3707714_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000002986 217.0
TLS2_k127_3707714_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000001488 193.0
TLS2_k127_3707714_7 Hydrogenase expression K04651 - - 0.0000000000000000000000002534 113.0
TLS2_k127_3707714_8 Ferredoxin - - - 0.0000000000000001747 85.0
TLS2_k127_3707714_9 - - - - 0.000000000001884 72.0
TLS2_k127_3714114_0 Binding-protein-dependent transport system inner membrane component K10234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 426.0
TLS2_k127_3714114_1 Binding-protein-dependent transport system inner membrane component K10233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 409.0
TLS2_k127_3714114_2 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 387.0
TLS2_k127_3714114_3 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 353.0
TLS2_k127_3714114_4 Pfam Uncharacterised protein family UPF0047 - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000003195 222.0
TLS2_k127_3714114_5 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000001161 170.0
TLS2_k127_3723367_0 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K15521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 601.0
TLS2_k127_3723367_1 Histidine kinase K07768 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 514.0
TLS2_k127_3723367_10 Putative bacterial sensory transduction regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000001948 228.0
TLS2_k127_3723367_11 domain protein - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000007991 221.0
TLS2_k127_3723367_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000614 213.0
TLS2_k127_3723367_13 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000001885 217.0
TLS2_k127_3723367_14 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000001216 214.0
TLS2_k127_3723367_15 Transcriptional regulator - - - 0.0000000000000000000000000000000000001389 153.0
TLS2_k127_3723367_16 Protein of unknown function (DUF2516) - - - 0.00000000000000000000000285 105.0
TLS2_k127_3723367_17 - - - - 0.0000000000000000001298 96.0
TLS2_k127_3723367_18 - K16645 - - 0.000000004573 69.0
TLS2_k127_3723367_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 429.0
TLS2_k127_3723367_3 FIST C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 426.0
TLS2_k127_3723367_4 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 406.0
TLS2_k127_3723367_5 response regulator, receiver K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 413.0
TLS2_k127_3723367_6 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 392.0
TLS2_k127_3723367_7 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 376.0
TLS2_k127_3723367_8 PhoU domain K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 304.0
TLS2_k127_3723367_9 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003877 274.0
TLS2_k127_3748094_0 Belongs to the AAA ATPase family - - - 4.817e-248 782.0
TLS2_k127_3748094_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.122e-225 704.0
TLS2_k127_3748094_10 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000000000001639 195.0
TLS2_k127_3748094_11 GTP-binding protein TypA K06207 - - 0.000001286 50.0
TLS2_k127_3748094_12 STAS domain - - - 0.000002125 55.0
TLS2_k127_3748094_2 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 556.0
TLS2_k127_3748094_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 556.0
TLS2_k127_3748094_4 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 364.0
TLS2_k127_3748094_5 Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway K15525 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 3.5.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 331.0
TLS2_k127_3748094_6 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004281 274.0
TLS2_k127_3748094_7 4Fe-4S binding domain K05524 - - 0.00000000000000000000000000000000000000000000000000000000000001182 220.0
TLS2_k127_3748094_8 acetyltransferase K22476 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000002217 224.0
TLS2_k127_3748094_9 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000002201 204.0
TLS2_k127_3748325_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1209.0
TLS2_k127_3748325_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 538.0
TLS2_k127_3748325_10 negative regulation of DNA recombination - - - 0.0000000000000000000000000002295 128.0
TLS2_k127_3748325_11 FMN binding - - - 0.0000000000000001237 80.0
TLS2_k127_3748325_12 Acetyltransferase (GNAT) domain - - - 0.000000000000001238 90.0
TLS2_k127_3748325_13 - - - - 0.000000000329 68.0
TLS2_k127_3748325_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 480.0
TLS2_k127_3748325_3 spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 431.0
TLS2_k127_3748325_4 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 383.0
TLS2_k127_3748325_5 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 372.0
TLS2_k127_3748325_6 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 333.0
TLS2_k127_3748325_7 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 327.0
TLS2_k127_3748325_8 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001052 289.0
TLS2_k127_3748325_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003887 243.0
TLS2_k127_3750455_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1 0.0 1295.0
TLS2_k127_3750455_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.99.16 4.671e-280 885.0
TLS2_k127_3750455_10 PaaX-like protein K02616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003493 283.0
TLS2_k127_3750455_11 - - - - 0.000000000000000000000000000000000000001308 155.0
TLS2_k127_3750455_12 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000003354 115.0
TLS2_k127_3750455_2 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 1.164e-270 856.0
TLS2_k127_3750455_3 Trehalose synthase K05343 GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576 3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 471.0
TLS2_k127_3750455_4 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 398.0
TLS2_k127_3750455_5 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 389.0
TLS2_k127_3750455_6 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 345.0
TLS2_k127_3750455_7 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 323.0
TLS2_k127_3750455_8 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 321.0
TLS2_k127_3750455_9 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 300.0
TLS2_k127_3766386_0 ATP-binding region, ATPase domain protein - - - 0.0 1142.0
TLS2_k127_3766386_1 Protein tyrosine kinase - - - 4e-323 1057.0
TLS2_k127_3766386_10 ErfK YbiS YcfS YnhG family protein - GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0019538,GO:0030203,GO:0030312,GO:0042546,GO:0043170,GO:0044085,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 465.0
TLS2_k127_3766386_11 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 456.0
TLS2_k127_3766386_12 Elongator protein 3, MiaB family, Radical SAM K21224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 442.0
TLS2_k127_3766386_13 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 424.0
TLS2_k127_3766386_14 transmembrane signaling receptor activity K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009692 402.0
TLS2_k127_3766386_15 60Kd inner membrane protein K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 370.0
TLS2_k127_3766386_16 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 358.0
TLS2_k127_3766386_17 Flavodoxin reductases ferredoxin-NADPH reductases family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 362.0
TLS2_k127_3766386_18 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 368.0
TLS2_k127_3766386_19 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 342.0
TLS2_k127_3766386_2 Transcriptional regulator - - - 7.462e-228 740.0
TLS2_k127_3766386_20 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 316.0
TLS2_k127_3766386_21 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 325.0
TLS2_k127_3766386_22 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 315.0
TLS2_k127_3766386_23 glutamine amidotransferase K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 319.0
TLS2_k127_3766386_24 L-phenylalanine transmembrane transporter activity K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 327.0
TLS2_k127_3766386_25 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 322.0
TLS2_k127_3766386_26 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 309.0
TLS2_k127_3766386_27 NmrA-like family K19267 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 320.0
TLS2_k127_3766386_28 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 300.0
TLS2_k127_3766386_29 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002975 260.0
TLS2_k127_3766386_3 Belongs to the aldehyde dehydrogenase family - - - 1.17e-225 709.0
TLS2_k127_3766386_30 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000001643 252.0
TLS2_k127_3766386_31 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000164 235.0
TLS2_k127_3766386_32 PFAM ATP-binding region ATPase domain protein, histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001257 245.0
TLS2_k127_3766386_33 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000000000000000000000002407 209.0
TLS2_k127_3766386_34 Belongs to the sigma-70 factor family - - - 0.00000000000000000000000000000000000000000000000000000000002621 214.0
TLS2_k127_3766386_35 Dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000001681 213.0
TLS2_k127_3766386_36 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000005335 201.0
TLS2_k127_3766386_37 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000002629 177.0
TLS2_k127_3766386_38 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000001335 168.0
TLS2_k127_3766386_39 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000001572 144.0
TLS2_k127_3766386_4 CHAT domain - - - 6.405e-220 716.0
TLS2_k127_3766386_40 Belongs to the glycosyl hydrolase 18 family - - - 0.0000000000001041 85.0
TLS2_k127_3766386_41 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000002118 63.0
TLS2_k127_3766386_42 - - - - 0.00000009015 61.0
TLS2_k127_3766386_43 Scramblase - - - 0.000000936 63.0
TLS2_k127_3766386_45 - - - - 0.0003415 49.0
TLS2_k127_3766386_5 Zinc-binding dehydrogenase K00055 - 1.1.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 605.0
TLS2_k127_3766386_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 555.0
TLS2_k127_3766386_7 Rieske [2Fe-2S] domain K19982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 534.0
TLS2_k127_3766386_8 FAD dependent oxidoreductase K00109 - 1.1.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 504.0
TLS2_k127_3766386_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 473.0
TLS2_k127_3767164_0 phytoene K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 617.0
TLS2_k127_3767164_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 455.0
TLS2_k127_3767164_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 327.0
TLS2_k127_3767164_3 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001445 295.0
TLS2_k127_3767164_4 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000002497 195.0
TLS2_k127_3767164_5 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000003316 178.0
TLS2_k127_3767164_6 Pentapeptide repeat protein - - - 0.0000000000000000000000000000000000000006863 163.0
TLS2_k127_3767164_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000001567 164.0
TLS2_k127_3767164_8 - - - - 0.0000000000178 77.0
TLS2_k127_3778971_0 Acyl-CoA dehydrogenase, middle domain - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 3.133e-286 893.0
TLS2_k127_3778971_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 563.0
TLS2_k127_3778971_10 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003901 273.0
TLS2_k127_3778971_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002764 250.0
TLS2_k127_3778971_12 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000004294 232.0
TLS2_k127_3778971_13 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000007014 225.0
TLS2_k127_3778971_14 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000000000000000263 198.0
TLS2_k127_3778971_15 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000102 151.0
TLS2_k127_3778971_16 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.000000000000000000000000000000000002888 147.0
TLS2_k127_3778971_17 PFAM cyclase family protein - - - 0.000000000000000000000000000000000181 144.0
TLS2_k127_3778971_18 PFAM TadE family protein - - - 0.00000000000000000000000000000000074 136.0
TLS2_k127_3778971_19 - - - - 0.00000000000000000000000006387 112.0
TLS2_k127_3778971_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 430.0
TLS2_k127_3778971_20 - - - - 0.00000000000000000000002462 111.0
TLS2_k127_3778971_3 cell division ATP-binding protein FtsE K09812 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 395.0
TLS2_k127_3778971_4 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 398.0
TLS2_k127_3778971_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 402.0
TLS2_k127_3778971_6 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 361.0
TLS2_k127_3778971_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 356.0
TLS2_k127_3778971_8 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 320.0
TLS2_k127_3778971_9 peptidase K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 308.0
TLS2_k127_3798006_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1076.0
TLS2_k127_3798006_1 endonuclease exonuclease phosphatase K07004 - - 0.0 1035.0
TLS2_k127_3798006_10 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007265 246.0
TLS2_k127_3798006_11 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000001353 216.0
TLS2_k127_3798006_12 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000003569 224.0
TLS2_k127_3798006_13 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000003234 204.0
TLS2_k127_3798006_14 pfam nlp p60 - - - 0.00000000000000000000000000000000000000000004814 175.0
TLS2_k127_3798006_15 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000756 170.0
TLS2_k127_3798006_16 Hypothetical methyltransferase - - - 0.00000000000000000000000000000000000000002228 169.0
TLS2_k127_3798006_17 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000257 171.0
TLS2_k127_3798006_18 - - - - 0.00000000000000000000000000000000002668 142.0
TLS2_k127_3798006_19 sulfurtransferase - - - 0.000000000000000000000000000000005286 134.0
TLS2_k127_3798006_2 Alkyl hydroperoxide reductase K03387 - - 8.759e-244 766.0
TLS2_k127_3798006_20 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000000005439 129.0
TLS2_k127_3798006_21 Belongs to the thioredoxin family K00384,K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.000000000000000000000000000001845 126.0
TLS2_k127_3798006_22 Sulfurtransferase TusA - - - 0.000000000000000000000000000001934 124.0
TLS2_k127_3798006_23 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000002581 121.0
TLS2_k127_3798006_24 - - - - 0.000000000000000000001468 96.0
TLS2_k127_3798006_3 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.204e-216 702.0
TLS2_k127_3798006_4 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 458.0
TLS2_k127_3798006_5 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 432.0
TLS2_k127_3798006_6 Neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 381.0
TLS2_k127_3798006_7 LysR substrate binding domain K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 372.0
TLS2_k127_3798006_8 Alkyl hydroperoxide reductase K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 347.0
TLS2_k127_3798006_9 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 354.0
TLS2_k127_3808380_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 6.734e-313 979.0
TLS2_k127_3808380_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 2.42e-198 625.0
TLS2_k127_3808380_10 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 339.0
TLS2_k127_3808380_11 Glycosyl transferase, family 2 K20444 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 355.0
TLS2_k127_3808380_12 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 357.0
TLS2_k127_3808380_13 ABC transporter K09693 - 3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 318.0
TLS2_k127_3808380_14 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 319.0
TLS2_k127_3808380_15 SpoIID LytB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 328.0
TLS2_k127_3808380_16 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008830,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002942 271.0
TLS2_k127_3808380_17 Glycosyl transferase, family 2 K07011,K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004088 294.0
TLS2_k127_3808380_18 Transport permease protein K09692 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003001 280.0
TLS2_k127_3808380_19 Amino acid-binding act domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006508 232.0
TLS2_k127_3808380_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 622.0
TLS2_k127_3808380_20 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000001138 216.0
TLS2_k127_3808380_21 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - - 0.00000000000000000000000000000000000000000000000000004754 196.0
TLS2_k127_3808380_22 Rhamnan synthesis protein F - - - 0.00000000000000000000000000000000000000000000000000006479 199.0
TLS2_k127_3808380_23 pathogenesis - - - 0.0000000000000000000000000000002038 143.0
TLS2_k127_3808380_3 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 610.0
TLS2_k127_3808380_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 563.0
TLS2_k127_3808380_5 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 529.0
TLS2_k127_3808380_6 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 482.0
TLS2_k127_3808380_7 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 507.0
TLS2_k127_3808380_8 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 420.0
TLS2_k127_3808380_9 3-methyladenine DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 419.0
TLS2_k127_3826383_0 Superfamily I DNA and RNA helicases and helicase subunits - - - 1.021e-267 878.0
TLS2_k127_3826383_1 Penicillin amidase K01434 - 3.5.1.11 1.314e-263 843.0
TLS2_k127_3826383_10 LuxR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004869 273.0
TLS2_k127_3826383_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001236 269.0
TLS2_k127_3826383_12 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006751 276.0
TLS2_k127_3826383_13 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006955 247.0
TLS2_k127_3826383_14 Molybdenum cofactor synthesis K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000001123 233.0
TLS2_k127_3826383_15 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000003976 231.0
TLS2_k127_3826383_16 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000135 223.0
TLS2_k127_3826383_17 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000001961 205.0
TLS2_k127_3826383_18 Subtilase family K14743 - - 0.0000000000000000000000000000000000000000000008457 187.0
TLS2_k127_3826383_19 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000542 168.0
TLS2_k127_3826383_2 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 1.775e-207 666.0
TLS2_k127_3826383_20 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000002057 160.0
TLS2_k127_3826383_21 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000006282 154.0
TLS2_k127_3826383_22 - - - - 0.00000000000000000000000000001093 126.0
TLS2_k127_3826383_23 regulatory protein, FmdB family - - - 0.00000000000000000000000001162 115.0
TLS2_k127_3826383_24 SAF - - - 0.00000000000000000002869 100.0
TLS2_k127_3826383_25 - - - - 0.00000000000000002122 86.0
TLS2_k127_3826383_26 - - - - 0.00000000000000002658 96.0
TLS2_k127_3826383_27 - - - - 0.00000000003614 70.0
TLS2_k127_3826383_28 - - - - 0.0003809 48.0
TLS2_k127_3826383_3 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 3.764e-197 625.0
TLS2_k127_3826383_4 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 476.0
TLS2_k127_3826383_5 Molybdenum cofactor synthesis domain protein K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 461.0
TLS2_k127_3826383_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 374.0
TLS2_k127_3826383_7 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 366.0
TLS2_k127_3826383_8 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 331.0
TLS2_k127_3826383_9 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001156 301.0
TLS2_k127_3832042_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 546.0
TLS2_k127_3832042_10 Predicted nucleotidyltransferase K07074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 314.0
TLS2_k127_3832042_11 Domain of unknown function (DUF4397) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 295.0
TLS2_k127_3832042_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 301.0
TLS2_k127_3832042_13 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 290.0
TLS2_k127_3832042_14 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124,K15734 - 1.1.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000001607 284.0
TLS2_k127_3832042_15 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001621 253.0
TLS2_k127_3832042_18 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000003741 199.0
TLS2_k127_3832042_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 531.0
TLS2_k127_3832042_20 peptidase C60 sortase A and B - - - 0.00000000000000000000000000000000000000000000000002198 187.0
TLS2_k127_3832042_21 - - - - 0.0000000000000000000000000000000000000000000000002161 178.0
TLS2_k127_3832042_22 Polyketide cyclase - - - 0.00000000000000000000000000000000000000000000106 169.0
TLS2_k127_3832042_23 Transcriptional regulator - - - 0.000000000000000000000000000000000000002929 158.0
TLS2_k127_3832042_24 - - - - 0.000000000000000000000000000000000000066 150.0
TLS2_k127_3832042_25 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000001738 154.0
TLS2_k127_3832042_26 Anti-sigma-K factor rskA - - - 0.00000000000000002797 92.0
TLS2_k127_3832042_27 Predicted nucleotidyltransferase K07074 - - 0.000000000001898 68.0
TLS2_k127_3832042_28 F420H(2)-dependent quinone reductase - - - 0.000000005908 64.0
TLS2_k127_3832042_3 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 415.0
TLS2_k127_3832042_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 394.0
TLS2_k127_3832042_5 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 392.0
TLS2_k127_3832042_6 Bifunctional deaminase-reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000085 366.0
TLS2_k127_3832042_7 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 355.0
TLS2_k127_3832042_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 349.0
TLS2_k127_3832042_9 B12 binding domain K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 342.0
TLS2_k127_3865098_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 7.766e-253 795.0
TLS2_k127_3865098_1 Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 528.0
TLS2_k127_3865098_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001985 247.0
TLS2_k127_3865098_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001449 235.0
TLS2_k127_3865098_12 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000008871 215.0
TLS2_k127_3865098_13 PAS fold - - - 0.000000000000000000000000000000000000000000000000000004817 218.0
TLS2_k127_3865098_14 Protein of unknown function (DUF4240) - - - 0.00000000000000000000000000000000000000000000008902 178.0
TLS2_k127_3865098_15 Belongs to the UPF0225 family K09858 - - 0.0000000000000000000000000000000000000000126 157.0
TLS2_k127_3865098_16 - - - - 0.00000000000000000000001595 109.0
TLS2_k127_3865098_17 Histidine kinase - - - 0.0000000000000000001748 100.0
TLS2_k127_3865098_18 amine dehydrogenase activity - - - 0.00000000000001987 87.0
TLS2_k127_3865098_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 483.0
TLS2_k127_3865098_20 Antibiotic biosynthesis monooxygenase - - - 0.00000001266 61.0
TLS2_k127_3865098_21 antisigma factor binding K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000001289 62.0
TLS2_k127_3865098_22 - - - - 0.0003718 44.0
TLS2_k127_3865098_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 418.0
TLS2_k127_3865098_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 319.0
TLS2_k127_3865098_5 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 325.0
TLS2_k127_3865098_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 319.0
TLS2_k127_3865098_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 317.0
TLS2_k127_3865098_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008542 290.0
TLS2_k127_3865098_9 pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008361 252.0
TLS2_k127_391075_0 PFAM Glycosyl transferase family 2 - - - 2.401e-207 700.0
TLS2_k127_391075_1 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 476.0
TLS2_k127_391075_2 Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives K12234 GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000006442 275.0
TLS2_k127_391075_3 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity - - - 0.0000000000000000000000000000000000000000000003236 184.0
TLS2_k127_391075_4 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000000000144 153.0
TLS2_k127_3942125_0 associated with various cellular activities K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1521.0
TLS2_k127_3942125_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0008150,GO:0040007 6.1.1.6 1.102e-232 729.0
TLS2_k127_3942125_10 FES K03575 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 400.0
TLS2_k127_3942125_11 decarboxylase K01607,K14727 - 3.1.1.24,4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 421.0
TLS2_k127_3942125_12 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 397.0
TLS2_k127_3942125_13 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 379.0
TLS2_k127_3942125_14 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits K21210 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 355.0
TLS2_k127_3942125_15 TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family K02624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 333.0
TLS2_k127_3942125_16 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 313.0
TLS2_k127_3942125_17 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 304.0
TLS2_k127_3942125_18 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 303.0
TLS2_k127_3942125_19 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 295.0
TLS2_k127_3942125_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 611.0
TLS2_k127_3942125_20 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 301.0
TLS2_k127_3942125_21 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006341 282.0
TLS2_k127_3942125_22 N-acetylglutamate synthase K00619 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000006987 239.0
TLS2_k127_3942125_23 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000000004871 234.0
TLS2_k127_3942125_24 Dihydroxyacetone kinase K05879 - 2.7.1.121 0.00000000000000000000000000000000000000000000000000000001793 208.0
TLS2_k127_3942125_25 GDP-mannose 4,6 dehydratase K21214 - - 0.0000000000000000000000000000000000000000000000000000007694 212.0
TLS2_k127_3942125_26 pathogenesis - - - 0.0000000000000000000000000000000000000000007 161.0
TLS2_k127_3942125_27 cellulose binding K13735 - - 0.00000000000000000000000000000000000000009263 175.0
TLS2_k127_3942125_28 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000004285 146.0
TLS2_k127_3942125_29 - - - - 0.000000000000000000000006372 119.0
TLS2_k127_3942125_3 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process K07067 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 573.0
TLS2_k127_3942125_30 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000004834 61.0
TLS2_k127_3942125_31 - - - - 0.0001307 48.0
TLS2_k127_3942125_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 583.0
TLS2_k127_3942125_5 PFAM Glycosyl transferase, group 1 K21011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 493.0
TLS2_k127_3942125_6 epimerase dehydratase K01710,K08678,K21211 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 482.0
TLS2_k127_3942125_7 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 437.0
TLS2_k127_3942125_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 440.0
TLS2_k127_3942125_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 422.0
TLS2_k127_3944968_0 exo-alpha-(2->6)-sialidase activity K00368,K07004,K20276 - 1.7.2.1 0.0 1099.0
TLS2_k127_3944968_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 388.0
TLS2_k127_3944968_2 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002562 297.0
TLS2_k127_3944968_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004543 261.0
TLS2_k127_3944968_4 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000003801 232.0
TLS2_k127_3944968_5 Protoglobin - - - 0.00000000000000000000000000000000000000000000000000000003399 202.0
TLS2_k127_3944968_6 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000001947 188.0
TLS2_k127_3944968_7 distant relative of homeotic protein bithoraxoid K07131 - - 0.00000000000000000000000000000000000000002169 169.0
TLS2_k127_3944968_8 Belongs to the ompA family - - - 0.000000000000000004731 95.0
TLS2_k127_3950561_0 Belongs to the GcvT family - - - 0.0 1290.0
TLS2_k127_3950561_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.472e-227 718.0
TLS2_k127_3950561_10 PaaX-like protein K02616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 309.0
TLS2_k127_3950561_11 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000001203 226.0
TLS2_k127_3950561_12 - - - - 0.00000000000000000000000000000000000000000000000000000000003154 235.0
TLS2_k127_3950561_13 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000003963 221.0
TLS2_k127_3950561_14 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000005841 197.0
TLS2_k127_3950561_15 Domain of unknown function (DUF4082) - - - 0.000000001984 70.0
TLS2_k127_3950561_2 PFAM monooxygenase FAD-binding K00481 - 1.14.13.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 575.0
TLS2_k127_3950561_3 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 576.0
TLS2_k127_3950561_4 PFAM Sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 426.0
TLS2_k127_3950561_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00446 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 381.0
TLS2_k127_3950561_6 Electron transfer flavoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 352.0
TLS2_k127_3950561_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 365.0
TLS2_k127_3950561_8 Transcriptional regulator IclR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 322.0
TLS2_k127_3950561_9 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 319.0
TLS2_k127_3955676_0 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 455.0
TLS2_k127_3955676_1 Thioredoxin K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 387.0
TLS2_k127_3955676_2 Thiamine-binding protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000002626 156.0
TLS2_k127_3955676_3 - - - - 0.000000000000000000000000000000000000001567 164.0
TLS2_k127_3955676_5 TIGRFAM Diguanylate cyclase K13069 - 2.7.7.65 0.000000000000005496 89.0
TLS2_k127_4029891_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 3.702e-228 716.0
TLS2_k127_4029891_1 Fructose-bisphosphate aldolase K01624 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 587.0
TLS2_k127_4029891_2 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 600.0
TLS2_k127_4029891_3 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 402.0
TLS2_k127_4042885_0 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 GO:0002790,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0020012,GO:0030312,GO:0030682,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0040007,GO:0042783,GO:0042886,GO:0043207,GO:0044110,GO:0044116,GO:0044117,GO:0044315,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136 - 5.358e-201 638.0
TLS2_k127_4042885_1 WXG100 protein secretion system (Wss), protein YukD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 348.0
TLS2_k127_4042885_2 Type VII secretion system ESX-1, transport TM domain B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 342.0
TLS2_k127_4042885_3 Peptidase S8 and S53 subtilisin kexin sedolisin K14743 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001904 295.0
TLS2_k127_4042885_4 translation initiation factor activity K00694 - 2.4.1.12 0.000000000000000000000000000000000000148 165.0
TLS2_k127_4042885_5 YbaB/EbfC DNA-binding family - - - 0.00000000000000000005587 98.0
TLS2_k127_4042885_6 Calpain family cysteine protease - - - 0.000000000000000001138 103.0
TLS2_k127_4042885_8 - - - - 0.0002252 49.0
TLS2_k127_4047119_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 8.315e-292 912.0
TLS2_k127_4047119_1 Transcriptional regulator - - - 1.323e-226 742.0
TLS2_k127_4047119_10 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000005285 171.0
TLS2_k127_4047119_11 GGDEF domain containing protein K14051 - 3.1.4.52 0.00000000000000000000000000000000000000001849 168.0
TLS2_k127_4047119_12 - - - - 0.000000000000000000000000000000000000001084 155.0
TLS2_k127_4047119_13 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.00000000000000000000000000000000477 136.0
TLS2_k127_4047119_14 ArsR family transcriptional regulator - - - 0.000000000000000000000000000000007313 128.0
TLS2_k127_4047119_15 Protein conserved in bacteria - - - 0.00000000000000000000000000000008179 138.0
TLS2_k127_4047119_16 Cold shock protein K03704 - - 0.00000000000000000000000000003238 120.0
TLS2_k127_4047119_17 Protein conserved in bacteria - - - 0.000000000000000005371 88.0
TLS2_k127_4047119_18 - - - - 0.00000000000000001889 88.0
TLS2_k127_4047119_19 Lipopolysaccharide assembly protein A domain - - - 0.00000000000000006304 86.0
TLS2_k127_4047119_2 PFAM FAD linked oxidase domain protein - - - 4.826e-194 616.0
TLS2_k127_4047119_20 antisigma factor binding - - - 0.00000000007852 70.0
TLS2_k127_4047119_22 Domain of unknown function (DUF4386) - - - 0.0003059 46.0
TLS2_k127_4047119_3 synthase K00697,K16055 GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 509.0
TLS2_k127_4047119_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 373.0
TLS2_k127_4047119_5 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 372.0
TLS2_k127_4047119_6 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 331.0
TLS2_k127_4047119_7 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 310.0
TLS2_k127_4047119_8 ANTAR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002704 251.0
TLS2_k127_4047119_9 Asp23 family, cell envelope-related function - - - 0.0000000000000000000000000000000000000000000000000132 188.0
TLS2_k127_4074572_0 NADPH-dependent glutamate synthase beta chain-like oxidoreductase - - - 6.625e-231 740.0
TLS2_k127_4074572_1 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 590.0
TLS2_k127_4074572_10 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 332.0
TLS2_k127_4074572_11 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 289.0
TLS2_k127_4074572_12 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004318 282.0
TLS2_k127_4074572_13 Cobalt ABC transporter K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002026 291.0
TLS2_k127_4074572_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000002466 213.0
TLS2_k127_4074572_15 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000007646 196.0
TLS2_k127_4074572_16 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000001702 180.0
TLS2_k127_4074572_17 NADH ubiquinone oxidoreductase, 20 Kd subunit K18023 - 1.12.7.2 0.00000000000000000000000000000000000000000004393 168.0
TLS2_k127_4074572_18 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000000000001139 159.0
TLS2_k127_4074572_19 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000000001892 153.0
TLS2_k127_4074572_2 PFAM Radical SAM K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 562.0
TLS2_k127_4074572_20 PDGLE domain K02009 - - 0.0000000000000000000000000002445 119.0
TLS2_k127_4074572_21 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.0000000000000000000002321 108.0
TLS2_k127_4074572_22 - - - - 0.00000000000000003218 84.0
TLS2_k127_4074572_23 Part of the ABC transporter FtsEX involved in - - - 0.00000000338 64.0
TLS2_k127_4074572_24 4Fe-4S binding domain - - - 0.000000188 63.0
TLS2_k127_4074572_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000005979 61.0
TLS2_k127_4074572_3 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 546.0
TLS2_k127_4074572_4 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05559,K05565 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 514.0
TLS2_k127_4074572_5 PFAM binding-protein-dependent transport systems inner membrane component K02026,K10119 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 455.0
TLS2_k127_4074572_6 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 459.0
TLS2_k127_4074572_7 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 398.0
TLS2_k127_4074572_8 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 391.0
TLS2_k127_4074572_9 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 343.0
TLS2_k127_4086333_0 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 572.0
TLS2_k127_4086333_1 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 549.0
TLS2_k127_4086333_2 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 456.0
TLS2_k127_4086333_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 408.0
TLS2_k127_4086333_4 Membrane-bound lytic murein transglycosylase - - - 0.0000000000000000000000000000000000000000000000000006623 203.0
TLS2_k127_4086333_5 Bacterial Ig-like domain (group 3) - - - 0.00000000000000000000000000000000000000006658 171.0
TLS2_k127_4086333_6 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.000000000000000000003233 108.0
TLS2_k127_4090605_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 3.032e-309 964.0
TLS2_k127_4090605_1 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 3.877e-251 784.0
TLS2_k127_4090605_10 N-acylglucosamine 2-epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 532.0
TLS2_k127_4090605_11 tRNA-splicing ligase RtcB K14415,K18148 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 532.0
TLS2_k127_4090605_12 ERCC4 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 481.0
TLS2_k127_4090605_13 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 477.0
TLS2_k127_4090605_14 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 454.0
TLS2_k127_4090605_15 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 433.0
TLS2_k127_4090605_16 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 413.0
TLS2_k127_4090605_17 SWIM zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 436.0
TLS2_k127_4090605_18 Lytic transglycolase K20628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 385.0
TLS2_k127_4090605_19 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 381.0
TLS2_k127_4090605_2 Glycogen debranching enzyme - - - 2.437e-249 799.0
TLS2_k127_4090605_20 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 377.0
TLS2_k127_4090605_21 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 343.0
TLS2_k127_4090605_22 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 338.0
TLS2_k127_4090605_23 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 357.0
TLS2_k127_4090605_24 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 308.0
TLS2_k127_4090605_25 Glycoside-hydrolase family GH114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 306.0
TLS2_k127_4090605_26 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 327.0
TLS2_k127_4090605_27 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000176 295.0
TLS2_k127_4090605_28 RF-1 domain K02839 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000302 257.0
TLS2_k127_4090605_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008462 238.0
TLS2_k127_4090605_3 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 2.656e-229 746.0
TLS2_k127_4090605_30 - - - - 0.000000000000000000000000000000000000000000000000000000000006547 214.0
TLS2_k127_4090605_31 RNA 2'-phosphotransferase, Tpt1 / KptA family K07559 - - 0.000000000000000000000000000000000000000000000000000000000006733 218.0
TLS2_k127_4090605_32 heme a metabolic process K02259 - - 0.0000000000000000000000000000000000000000000000000000001366 208.0
TLS2_k127_4090605_33 FCD - - - 0.000000000000000000000000000000000000000000000000003834 192.0
TLS2_k127_4090605_34 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000004323 192.0
TLS2_k127_4090605_35 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000001337 171.0
TLS2_k127_4090605_36 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000154 152.0
TLS2_k127_4090605_37 TIGRFAM ferredoxin III - - - 0.000000000000000000000000000000004319 136.0
TLS2_k127_4090605_38 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000001044 138.0
TLS2_k127_4090605_39 - - - - 0.000000000000000000000000000008649 125.0
TLS2_k127_4090605_4 acyl-CoA dehydrogenase K00252 - 1.3.8.6 7.621e-196 618.0
TLS2_k127_4090605_40 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000002616 107.0
TLS2_k127_4090605_41 Belongs to the UPF0354 family - - - 0.00000000000000000002689 104.0
TLS2_k127_4090605_42 Peptidase M50B-like - - - 0.0000000000000000002201 98.0
TLS2_k127_4090605_43 OmpA family - - - 0.00000000000000002932 94.0
TLS2_k127_4090605_44 Protein of unknown function (DUF3995) - - - 0.00000000000000003564 89.0
TLS2_k127_4090605_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K02574 - - 7.757e-195 628.0
TLS2_k127_4090605_6 PFAM aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 603.0
TLS2_k127_4090605_7 Multicopper oxidase - GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 612.0
TLS2_k127_4090605_8 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 590.0
TLS2_k127_4090605_9 Molecular chaperone. Has ATPase activity K04079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 577.0
TLS2_k127_4128938_0 Common central domain of tyrosinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 451.0
TLS2_k127_4128938_1 Ppx GppA phosphatase K01524 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 415.0
TLS2_k127_4128938_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 389.0
TLS2_k127_4128938_3 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 398.0
TLS2_k127_4128938_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 383.0
TLS2_k127_4128938_5 transport, permease protein K01990,K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 374.0
TLS2_k127_4128938_6 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 362.0
TLS2_k127_4128938_7 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 342.0
TLS2_k127_4128938_8 Cation transport protein K03498 - - 0.00007543 51.0
TLS2_k127_4175993_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 589.0
TLS2_k127_4175993_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 479.0
TLS2_k127_4175993_10 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 287.0
TLS2_k127_4175993_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007358 280.0
TLS2_k127_4175993_12 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003057 275.0
TLS2_k127_4175993_13 FCD - - - 0.0000000000000000000000004136 113.0
TLS2_k127_4175993_14 LemA family K03744 - - 0.00000000000000000008656 98.0
TLS2_k127_4175993_15 acetyltransferase - - - 0.0000000000000297 84.0
TLS2_k127_4175993_16 transcriptional regulator - - - 0.000000000004059 76.0
TLS2_k127_4175993_2 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 461.0
TLS2_k127_4175993_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 467.0
TLS2_k127_4175993_4 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 438.0
TLS2_k127_4175993_5 ABC transporter, ATP-binding protein K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 466.0
TLS2_k127_4175993_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 449.0
TLS2_k127_4175993_7 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 419.0
TLS2_k127_4175993_8 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 329.0
TLS2_k127_4175993_9 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 317.0
TLS2_k127_4184605_0 Ferrous iron transport protein B K04759 - - 4.512e-312 973.0
TLS2_k127_4184605_1 Beta-ketoacyl synthase, C-terminal domain K05551,K09458 - 2.3.1.179,2.3.1.235,2.3.1.260 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 601.0
TLS2_k127_4184605_10 NifU-like domain K07400 - - 0.0000000000000000000000000000000000000000000005769 179.0
TLS2_k127_4184605_11 iron ion homeostasis K04758 - - 0.0000000000000000000000196 104.0
TLS2_k127_4184605_12 TIGRFAM acyl carrier protein K02078 - - 0.000000000000000000001523 100.0
TLS2_k127_4184605_2 Fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 444.0
TLS2_k127_4184605_3 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 353.0
TLS2_k127_4184605_4 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 315.0
TLS2_k127_4184605_5 Belongs to the GcvT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005376 287.0
TLS2_k127_4184605_6 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000004805 235.0
TLS2_k127_4184605_7 KR domain K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000003889 211.0
TLS2_k127_4184605_8 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000003946 206.0
TLS2_k127_4184605_9 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000003125 183.0
TLS2_k127_421197_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 538.0
TLS2_k127_421197_1 PFAM penicillin-binding protein transpeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 371.0
TLS2_k127_421197_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 329.0
TLS2_k127_421197_3 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 326.0
TLS2_k127_421197_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000006104 171.0
TLS2_k127_421197_5 Fibronectin type III domain - - - 0.00000000000000000000000000000001626 149.0
TLS2_k127_421197_6 Domain of unknown function (DUF1918) - - - 0.000000000000000001566 86.0
TLS2_k127_421197_7 S-layer homology domain - - - 0.0000001845 66.0
TLS2_k127_4219585_0 PFAM Methane phenol toluene hydroxylase K15760 - 1.14.13.236 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 582.0
TLS2_k127_4219585_1 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 586.0
TLS2_k127_4219585_10 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008248 270.0
TLS2_k127_4219585_11 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002707 272.0
TLS2_k127_4219585_12 Pfam Isochorismatase K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000007044 256.0
TLS2_k127_4219585_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009714 262.0
TLS2_k127_4219585_14 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000000001157 205.0
TLS2_k127_4219585_15 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000004343 201.0
TLS2_k127_4219585_16 Rieske-like [2Fe-2S] domain K15762 - - 0.0000000000000000000000000000000000000000000002786 174.0
TLS2_k127_4219585_17 Domain of unknown function (DUF2017) - - - 0.00000000000000000000000000000000000000004398 161.0
TLS2_k127_4219585_18 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000851 158.0
TLS2_k127_4219585_19 Acts as a radical domain for damaged PFL and possibly other radical proteins K06866,K15763,K22361 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.14.13.236 0.0000000000000000000000000000000000003964 147.0
TLS2_k127_4219585_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 578.0
TLS2_k127_4219585_21 Toluene-4-monooxygenase system protein B (TmoB) K15761 - 1.14.13.236 0.000000000000000000000000006229 114.0
TLS2_k127_4219585_22 N-acetyltransferase - - - 0.000000000000000000000000008377 113.0
TLS2_k127_4219585_23 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000001808 81.0
TLS2_k127_4219585_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 418.0
TLS2_k127_4219585_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 418.0
TLS2_k127_4219585_5 PFAM Methane phenol toluene hydroxylase K15764 - 1.14.13.236 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 395.0
TLS2_k127_4219585_6 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 343.0
TLS2_k127_4219585_7 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0051704 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 311.0
TLS2_k127_4219585_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 284.0
TLS2_k127_4219585_9 Beta-lactamase superfamily domain - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 287.0
TLS2_k127_4219801_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 1.625e-233 757.0
TLS2_k127_4219801_1 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 4.594e-203 646.0
TLS2_k127_4219801_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 513.0
TLS2_k127_4219801_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 369.0
TLS2_k127_4219801_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 368.0
TLS2_k127_4219801_5 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 328.0
TLS2_k127_4219801_6 Domain of unknown function (DUF5063) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 320.0
TLS2_k127_4219801_7 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 318.0
TLS2_k127_4219801_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 0.000007034 51.0
TLS2_k127_4235526_0 Baseplate J-like protein - - - 6.698e-268 842.0
TLS2_k127_4235526_1 Phage tail protein (Tail_P2_I) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 623.0
TLS2_k127_4235526_10 GPW gp25 family protein K06903 - - 0.000000000000000000000000000000000000000000000000002892 187.0
TLS2_k127_4235526_11 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000001439 191.0
TLS2_k127_4235526_13 - - - - 0.0000000000063 78.0
TLS2_k127_4235526_14 membrane transporter protein - - - 0.0000000003452 63.0
TLS2_k127_4235526_15 - - - - 0.00000002884 66.0
TLS2_k127_4235526_16 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0001815 45.0
TLS2_k127_4235526_2 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 573.0
TLS2_k127_4235526_3 PFAM chorismate K01665,K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 404.0
TLS2_k127_4235526_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 409.0
TLS2_k127_4235526_5 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 312.0
TLS2_k127_4235526_6 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002801 270.0
TLS2_k127_4235526_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002878 259.0
TLS2_k127_4235526_8 Sporulation and cell division protein SsgA - - - 0.0000000000000000000000000000000000000000000000000000000000002378 220.0
TLS2_k127_4235526_9 - - - - 0.000000000000000000000000000000000000000000000000001452 207.0
TLS2_k127_4296880_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 602.0
TLS2_k127_4296880_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 415.0
TLS2_k127_4296880_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 349.0
TLS2_k127_4296880_3 PFAM helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 281.0
TLS2_k127_4296880_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000004433 207.0
TLS2_k127_4296880_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000001539 172.0
TLS2_k127_4296880_6 carbon utilization - - - 0.0000000000000000000000000005942 122.0
TLS2_k127_4300790_0 Multicopper oxidase - - - 0.0 1562.0
TLS2_k127_4300790_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 554.0
TLS2_k127_4300790_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 367.0
TLS2_k127_4300790_3 histidine kinase dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 323.0
TLS2_k127_4300790_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005712 298.0
TLS2_k127_4300790_5 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007271 269.0
TLS2_k127_4300790_6 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000000000000003195 218.0
TLS2_k127_4300790_7 AbiEi antitoxin C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000007551 216.0
TLS2_k127_4316529_0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - - 2.541e-299 933.0
TLS2_k127_4316529_1 alpha amylase, catalytic K01236 - 3.2.1.141 4.909e-278 876.0
TLS2_k127_4316529_2 Alcohol dehydrogenase GroES-like domain K18369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 597.0
TLS2_k127_4316529_3 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 430.0
TLS2_k127_4316529_4 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 390.0
TLS2_k127_4316529_5 Deaminase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 352.0
TLS2_k127_4316529_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 334.0
TLS2_k127_4316529_7 protein deglycation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 309.0
TLS2_k127_4316529_8 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.00000000000000000000000000000000000000006489 171.0
TLS2_k127_4316529_9 - - - - 0.0000000000000000000000000000000000000002645 155.0
TLS2_k127_4372085_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1865.0
TLS2_k127_4372085_1 Dehydrogenase K00294 - 1.2.1.88 4.611e-274 862.0
TLS2_k127_4372085_10 belongs to the sigma-70 factor family K03090 GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 291.0
TLS2_k127_4372085_11 HAD-superfamily hydrolase subfamily IA, variant 3 K07025,K18569 - - 0.0000000000000000000000000000000000000000000000000000000000001661 226.0
TLS2_k127_4372085_12 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000218 170.0
TLS2_k127_4372085_13 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly - - - 0.0000000000000000000000000000000000000000000008968 174.0
TLS2_k127_4372085_14 Protein of unknown function (DUF2505) - - - 0.00000000000000000000000000000000000000000001438 168.0
TLS2_k127_4372085_15 - - - - 0.000000000000000000000000000000000000001138 153.0
TLS2_k127_4372085_16 - - - - 0.00000000000000000000000000000000007069 149.0
TLS2_k127_4372085_17 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000002161 140.0
TLS2_k127_4372085_18 TadE-like protein - - - 0.00000000000000000000000000003412 132.0
TLS2_k127_4372085_19 anti-sigma regulatory factor K04757 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 2.7.11.1 0.000000000000000000000000001244 118.0
TLS2_k127_4372085_2 Histidine kinase K00936 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 9.749e-223 701.0
TLS2_k127_4372085_20 hydrolase activity, acting on ester bonds K15357,K19311 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0044237,GO:0044248 3.5.1.106 0.000000000000000000000000007186 122.0
TLS2_k127_4372085_21 - - - - 0.000000000000000000000000008047 125.0
TLS2_k127_4372085_22 Helix-turn-helix domain - - - 0.0000000000000000000002871 102.0
TLS2_k127_4372085_23 - - - - 0.000000000000006211 79.0
TLS2_k127_4372085_3 Flp pilus assembly protein ATPase CpaF K02283 - - 4.963e-196 626.0
TLS2_k127_4372085_4 Belongs to the long-chain O-acyltransferase family K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 522.0
TLS2_k127_4372085_5 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 393.0
TLS2_k127_4372085_6 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 364.0
TLS2_k127_4372085_7 bacterial-type flagellum organization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 349.0
TLS2_k127_4372085_8 PFAM Type II secretion system F domain K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 311.0
TLS2_k127_4372085_9 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 310.0
TLS2_k127_4403_0 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000001248 139.0
TLS2_k127_4403_1 Antibiotic biosynthesis monooxygenase K09932 - - 0.000000000000000000000000002492 120.0
TLS2_k127_4403_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000005607 108.0
TLS2_k127_4403_3 - - - - 0.000000000000000001897 99.0
TLS2_k127_4407560_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.484e-307 968.0
TLS2_k127_4407560_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 1.671e-216 679.0
TLS2_k127_4407560_2 Participates in both transcription termination and antitermination K02600 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 552.0
TLS2_k127_4407560_3 phosphatase activity K07025,K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 353.0
TLS2_k127_4407560_4 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 316.0
TLS2_k127_4407560_5 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000002016 175.0
TLS2_k127_4407560_6 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.0000000000000000000001877 108.0
TLS2_k127_4476975_0 Inosine-uridine preferring nucleoside hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 319.0
TLS2_k127_4476975_1 Protein of unknown function (DUF2695) - - - 0.00000000000000000000000000000000000000008806 154.0
TLS2_k127_4476975_2 HD domain - - - 0.000000000000000000000005895 104.0
TLS2_k127_4506981_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1702.0
TLS2_k127_4506981_1 PFAM Glycosyl transferase, family - - - 9.634e-206 708.0
TLS2_k127_4506981_2 - - - - 0.00000000000000000000000000000000000000009597 159.0
TLS2_k127_4506981_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position - - - 0.00000000000000000000004851 108.0
TLS2_k127_4614165_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1178.0
TLS2_k127_4614165_1 AAA ATPase domain - - - 1.924e-286 914.0
TLS2_k127_4614165_10 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 295.0
TLS2_k127_4614165_11 PucR C-terminal helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009493 253.0
TLS2_k127_4614165_12 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000001365 266.0
TLS2_k127_4614165_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005582 234.0
TLS2_k127_4614165_14 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000925 227.0
TLS2_k127_4614165_15 - - - - 0.000000000000000000000000000000000000000000000000000000000008797 209.0
TLS2_k127_4614165_16 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000009398 219.0
TLS2_k127_4614165_17 Protein of unknown function (DUF616) - - - 0.00000000000000000000000000000000000000000000000000000000005686 216.0
TLS2_k127_4614165_18 GXWXG protein - - - 0.00000000000000000000000000000000000000000000000000000009198 217.0
TLS2_k127_4614165_19 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000001054 200.0
TLS2_k127_4614165_2 PFAM TrkA-N domain protein - - - 2.49e-248 780.0
TLS2_k127_4614165_20 Ferric uptake regulator family K22297 - - 0.000000000000000000000000000000000000000000000000000002153 195.0
TLS2_k127_4614165_21 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000256 199.0
TLS2_k127_4614165_22 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000007417 192.0
TLS2_k127_4614165_23 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000002197 173.0
TLS2_k127_4614165_24 Domain of unknown function (DUF4383) - - - 0.0000000000000000000000000000000000000321 150.0
TLS2_k127_4614165_25 TfoX N-terminal domain - - - 0.0000000000000000000000000000000000000829 146.0
TLS2_k127_4614165_26 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000001259 155.0
TLS2_k127_4614165_27 Transcriptional regulator - - - 0.0000000000000000000000000003297 124.0
TLS2_k127_4614165_28 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000007797 108.0
TLS2_k127_4614165_29 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000001514 111.0
TLS2_k127_4614165_3 MMPL family K06994 - - 7.969e-245 779.0
TLS2_k127_4614165_30 - - - - 0.0000000000000000000000003069 110.0
TLS2_k127_4614165_31 - - - - 0.00000000000000000000001543 115.0
TLS2_k127_4614165_32 - - - - 0.0000000000000001305 86.0
TLS2_k127_4614165_33 transcription elongation factor, GreA GreB - - - 0.000000006646 60.0
TLS2_k127_4614165_34 - - - - 0.000000009758 59.0
TLS2_k127_4614165_4 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 2.358e-228 721.0
TLS2_k127_4614165_5 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 556.0
TLS2_k127_4614165_6 Alpha beta hydrolase K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 390.0
TLS2_k127_4614165_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 391.0
TLS2_k127_4614165_8 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 349.0
TLS2_k127_4614165_9 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 324.0
TLS2_k127_4691911_0 Excinuclease ATPase subunit - - - 0.0 1394.0
TLS2_k127_4691911_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 567.0
TLS2_k127_4691911_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 559.0
TLS2_k127_4691911_3 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 319.0
TLS2_k127_4691911_4 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002667 288.0
TLS2_k127_4691911_5 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001753 206.0
TLS2_k127_4691911_6 Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters - GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000001908 187.0
TLS2_k127_470020_0 polyketide synthase - - - 1.41e-200 655.0
TLS2_k127_470020_1 Activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002869 263.0
TLS2_k127_470020_2 - - - - 0.00000000000000000000000000000000000000000000000002595 184.0
TLS2_k127_470020_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000001004 122.0
TLS2_k127_4709569_0 extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 578.0
TLS2_k127_4709569_1 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 432.0
TLS2_k127_4709569_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 419.0
TLS2_k127_4709569_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000257 280.0
TLS2_k127_4709569_4 - - - - 0.0000000000000000000000000000000000000000155 161.0
TLS2_k127_4709569_5 - - - - 0.0000003215 55.0
TLS2_k127_4709731_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1 0.0 1633.0
TLS2_k127_4709731_1 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 408.0
TLS2_k127_4709731_2 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 341.0
TLS2_k127_4709731_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000006714 170.0
TLS2_k127_4709731_4 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000000000000006282 163.0
TLS2_k127_4709731_5 bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000007494 115.0
TLS2_k127_4718789_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 7.667e-196 621.0
TLS2_k127_4718789_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 601.0
TLS2_k127_4718789_10 penicillin-binding protein K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 358.0
TLS2_k127_4718789_11 Cell division initiation protein - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 345.0
TLS2_k127_4718789_12 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000001668 261.0
TLS2_k127_4718789_13 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000002874 240.0
TLS2_k127_4718789_14 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000000000000000000003071 224.0
TLS2_k127_4718789_15 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000005217 209.0
TLS2_k127_4718789_16 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.4.23.36 0.000000000000000000000000000000000000000000000000000001792 197.0
TLS2_k127_4718789_17 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 6.3.2.4 0.0000000000000000000000000000001438 134.0
TLS2_k127_4718789_18 integral membrane protein K02221 - - 0.00000000000000000000000000004244 119.0
TLS2_k127_4718789_19 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000008142 102.0
TLS2_k127_4718789_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 565.0
TLS2_k127_4718789_20 Domain of unknown function (DUF4339) - - - 0.000000000000000000001587 96.0
TLS2_k127_4718789_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0008150,GO:0040007 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 517.0
TLS2_k127_4718789_4 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 491.0
TLS2_k127_4718789_5 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 512.0
TLS2_k127_4718789_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 GO:0008150,GO:0040007 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 482.0
TLS2_k127_4718789_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K01924,K02563 - 2.4.1.227,6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 467.0
TLS2_k127_4718789_8 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 446.0
TLS2_k127_4718789_9 Belongs to the SEDS family K02563,K03588 GO:0008150,GO:0040007 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 430.0
TLS2_k127_4729979_0 N-6 DNA Methylase - - - 9.195e-211 670.0
TLS2_k127_4729979_1 cytochrome P-450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 568.0
TLS2_k127_4729979_10 Protein of unknown function (DUF2993) - - - 0.000000000000000000000001187 112.0
TLS2_k127_4729979_11 phosphatase - - - 0.000000000000000000005684 95.0
TLS2_k127_4729979_12 - - - - 0.00000000000000449 80.0
TLS2_k127_4729979_13 CopG domain protein DNA-binding domain protein - - - 0.000000005418 61.0
TLS2_k127_4729979_14 GGDEF domain - - - 0.00000004231 67.0
TLS2_k127_4729979_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 458.0
TLS2_k127_4729979_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K00455 - 1.13.11.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 447.0
TLS2_k127_4729979_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 404.0
TLS2_k127_4729979_5 Extradiol ring-cleavage dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009768 392.0
TLS2_k127_4729979_6 Aromatic acid exporter family member 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 301.0
TLS2_k127_4729979_7 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000001612 243.0
TLS2_k127_4729979_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000001401 184.0
TLS2_k127_4729979_9 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000006501 137.0
TLS2_k127_4732304_0 Glycosyl hydrolase family 3 C-terminal domain - - - 2.105e-282 886.0
TLS2_k127_4732304_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 506.0
TLS2_k127_4732304_10 Protein of unknown function (DUF4245) - - - 0.0000000000004675 81.0
TLS2_k127_4732304_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 514.0
TLS2_k127_4732304_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 486.0
TLS2_k127_4732304_4 RmuC domain protein K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 466.0
TLS2_k127_4732304_5 Predicted membrane protein (DUF2079) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 437.0
TLS2_k127_4732304_6 PfkB family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 340.0
TLS2_k127_4732304_7 Predicted membrane protein (DUF2079) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 350.0
TLS2_k127_4732304_8 Peptidyl-tRNA hydrolase - - - 0.00000000000000000000000000000000000000000000000009973 194.0
TLS2_k127_4732304_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000009257 98.0
TLS2_k127_4734257_0 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 454.0
TLS2_k127_4734257_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 437.0
TLS2_k127_4734257_2 phosphatidylinositol metabolic process K13671 - - 0.00000000007741 65.0
TLS2_k127_4735620_0 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 462.0
TLS2_k127_4735620_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K11608 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005488,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0019637,GO:0019693,GO:0019752,GO:0030497,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033818,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035336,GO:0035337,GO:0035383,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901567,GO:1901568,GO:1901576,GO:1901681 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 433.0
TLS2_k127_4735620_2 Polyphosphate kinase 2 (PPK2) K22468 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005525,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006183,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030808,GO:0031323,GO:0031326,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046777,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051704,GO:0055086,GO:0062012,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 409.0
TLS2_k127_4735620_3 Biotin attachment protein K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 400.0
TLS2_k127_4735620_4 - - - - 0.000000000000000000000000000000000000000000000000000000002683 208.0
TLS2_k127_4735620_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000001792 134.0
TLS2_k127_4736654_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1397.0
TLS2_k127_4736654_1 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 499.0
TLS2_k127_4736654_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 344.0
TLS2_k127_4736654_3 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000004616 207.0
TLS2_k127_4736654_4 - - - - 0.000000000000000000000000017 122.0
TLS2_k127_4736654_5 PFAM Peptidoglycan-binding lysin domain - - - 0.00000000000000000001118 96.0
TLS2_k127_4754797_0 4-alpha-glucanotransferase K00705 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 2.29e-314 978.0
TLS2_k127_4754797_1 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01322 - 3.4.21.26 2.371e-300 957.0
TLS2_k127_4754797_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000001705 225.0
TLS2_k127_4754797_11 Bacterial-like globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000002884 213.0
TLS2_k127_4754797_12 thioesterase K07107 - - 0.0000000000000000000000000000000000000000000001597 171.0
TLS2_k127_4754797_13 - - - - 0.00000000000000000000000000000000000000001514 167.0
TLS2_k127_4754797_14 - - - - 0.000000000000000000000009942 115.0
TLS2_k127_4754797_2 acyl-CoA dehydrogenase K00249,K00255 - 1.3.8.7,1.3.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 597.0
TLS2_k127_4754797_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 430.0
TLS2_k127_4754797_4 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 361.0
TLS2_k127_4754797_5 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 327.0
TLS2_k127_4754797_6 mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 300.0
TLS2_k127_4754797_7 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002676 256.0
TLS2_k127_4754797_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007 255.0
TLS2_k127_4754797_9 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000573 225.0
TLS2_k127_4771623_0 DEAD DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0 1307.0
TLS2_k127_4771623_1 Lysine 2,3-aminomutase K01844 - 5.4.3.3 2.778e-274 850.0
TLS2_k127_4771623_10 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003308 296.0
TLS2_k127_4771623_11 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000001832 254.0
TLS2_k127_4771623_12 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004725 240.0
TLS2_k127_4771623_13 Thioesterase superfamily K18014 - 4.3.1.14 0.000000000000000000000000000000000000000000000000000000372 197.0
TLS2_k127_4771623_14 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000001432 176.0
TLS2_k127_4771623_15 FxsA cytoplasmic membrane protein K07113 - - 0.00000005057 63.0
TLS2_k127_4771623_2 Lysine 2,3-aminomutase K01843 - 5.4.3.2 1.241e-247 772.0
TLS2_k127_4771623_3 Transfers the fatty acyl group on membrane lipoproteins K03820 GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070085,GO:0071704,GO:0071944,GO:0075136,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 550.0
TLS2_k127_4771623_4 Dehydrogenase K18012 - 1.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 497.0
TLS2_k127_4771623_5 SpoOM protein K06377 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 411.0
TLS2_k127_4771623_6 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 407.0
TLS2_k127_4771623_7 PFAM 5'-3' exonuclease, N-terminal resolvase-like domain - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 390.0
TLS2_k127_4771623_8 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 357.0
TLS2_k127_4771623_9 Diacylglycerol kinase K07029 GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 350.0
TLS2_k127_4781312_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1337.0
TLS2_k127_4781312_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 505.0
TLS2_k127_4781312_2 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000003275 173.0
TLS2_k127_4781312_3 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000002138 115.0
TLS2_k127_4794993_0 Alpha amylase, catalytic domain K01236 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0033942,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0071704,GO:1901575,GO:1901576 3.2.1.141 1.254e-248 781.0
TLS2_k127_4794993_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 573.0
TLS2_k127_4794993_10 PFAM GCN5-related N-acetyltransferase K02348 - - 0.00000000000000000000000000000000000000000000000705 183.0
TLS2_k127_4794993_11 - - - - 0.000000000000001167 82.0
TLS2_k127_4794993_13 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00003024 47.0
TLS2_k127_4794993_2 alpha beta K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 458.0
TLS2_k127_4794993_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 359.0
TLS2_k127_4794993_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001224 291.0
TLS2_k127_4794993_5 Domain of unknown function (DUF4191) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001472 252.0
TLS2_k127_4794993_6 Pyrimidine reductase, riboflavin biosynthesis K00082 - 1.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000002267 259.0
TLS2_k127_4794993_7 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000002652 222.0
TLS2_k127_4794993_8 SufE protein probably involved in Fe-S center assembly K02426 - - 0.0000000000000000000000000000000000000000000000000001088 190.0
TLS2_k127_4794993_9 - - - - 0.00000000000000000000000000000000000000000000000373 177.0
TLS2_k127_4798789_0 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 475.0
TLS2_k127_4798789_1 SPFH domain / Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 391.0
TLS2_k127_4798789_10 transport, permease protein K01992 - - 0.000000000000000000001481 94.0
TLS2_k127_4798789_11 - - - - 0.000005996 56.0
TLS2_k127_4798789_12 - - - - 0.00006222 50.0
TLS2_k127_4798789_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 389.0
TLS2_k127_4798789_3 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 335.0
TLS2_k127_4798789_4 Evidence 2b Function of strongly homologous gene K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 348.0
TLS2_k127_4798789_5 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 356.0
TLS2_k127_4798789_7 inositol 2-dehydrogenase activity K19181 - 1.1.1.292 0.000000000000000000000000000000000000000000000000000000000000000000000000000001426 274.0
TLS2_k127_4798789_8 OmpA family K03286 - - 0.000000000000000000000000000000000000000000000000000001034 207.0
TLS2_k127_4798789_9 RF-1 domain K15034 - - 0.00000000000000000000000000000000000000000000000002789 182.0
TLS2_k127_479892_0 Bacterial extracellular solute-binding protein K02027 - - 4.479e-230 717.0
TLS2_k127_479892_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K20023 - 4.2.1.156,4.2.1.42 1.988e-206 649.0
TLS2_k127_479892_10 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 336.0
TLS2_k127_479892_11 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 329.0
TLS2_k127_479892_12 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 313.0
TLS2_k127_479892_13 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000206 289.0
TLS2_k127_479892_14 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007277 262.0
TLS2_k127_479892_15 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001238 253.0
TLS2_k127_479892_16 Belongs to the P-Pant transferase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000005589 235.0
TLS2_k127_479892_17 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000007053 246.0
TLS2_k127_479892_18 Periplasmic binding proteins and sugar binding domain of LacI family K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000918 241.0
TLS2_k127_479892_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000139 230.0
TLS2_k127_479892_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18334 - 4.2.1.68 1.284e-198 626.0
TLS2_k127_479892_20 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000009333 219.0
TLS2_k127_479892_21 - - - - 0.00000000000000000000000000000000000000000000007973 178.0
TLS2_k127_479892_22 FCD - - - 0.000000000000000000000000000000000000000009226 163.0
TLS2_k127_479892_23 trisaccharide binding K03556 - - 0.000000000000000001005 89.0
TLS2_k127_479892_3 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 550.0
TLS2_k127_479892_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 479.0
TLS2_k127_479892_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 491.0
TLS2_k127_479892_6 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 432.0
TLS2_k127_479892_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18334 - 4.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 430.0
TLS2_k127_479892_8 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 378.0
TLS2_k127_479892_9 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 364.0
TLS2_k127_4813599_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 567.0
TLS2_k127_4813599_1 Domain of unknown function (DUF1768) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 366.0
TLS2_k127_4813599_10 - - - - 0.0000001184 60.0
TLS2_k127_4813599_11 PFAM Integrase catalytic - - - 0.0000004889 54.0
TLS2_k127_4813599_2 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 310.0
TLS2_k127_4813599_3 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000000000000000000005777 141.0
TLS2_k127_4813599_4 - - - - 0.00000000000000000000000000000115 125.0
TLS2_k127_4813599_6 - - - - 0.0000000000002245 74.0
TLS2_k127_4813599_7 2TM domain - - - 0.0000000000005139 73.0
TLS2_k127_4813599_8 HTH-like domain - - - 0.000000000002035 70.0
TLS2_k127_4813599_9 transposase activity K07483 - - 0.00000000194 61.0
TLS2_k127_4816918_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1144.0
TLS2_k127_4816918_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.318e-257 810.0
TLS2_k127_4816918_2 2-Nitropropane dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 606.0
TLS2_k127_4816918_3 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 479.0
TLS2_k127_4816918_4 membrane - - - 0.00000000000000000000000000000000000000001323 156.0
TLS2_k127_4817814_0 Prolyl oligopeptidase, N-terminal beta-propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 389.0
TLS2_k127_4817814_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001929 271.0
TLS2_k127_4817814_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000001759 224.0
TLS2_k127_4817814_3 OmpA family - - - 0.00000000000000000000005563 112.0
TLS2_k127_4817814_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000002395 79.0
TLS2_k127_4831213_0 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 370.0
TLS2_k127_4831213_1 - - - - 0.00000000000000000000000000000002845 132.0
TLS2_k127_4831213_2 - - - - 0.0000000000000000000000000000003956 132.0
TLS2_k127_4831213_3 - - - - 0.000000000000000000000005104 108.0
TLS2_k127_4831213_5 - - - - 0.0000005819 55.0
TLS2_k127_4835416_0 Fe-S oxidoreductase - - - 0.0 1040.0
TLS2_k127_4835416_1 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 417.0
TLS2_k127_4835416_10 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000000000003327 140.0
TLS2_k127_4835416_11 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000002371 89.0
TLS2_k127_4835416_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 359.0
TLS2_k127_4835416_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 352.0
TLS2_k127_4835416_4 flagellar hook-associated protein K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 314.0
TLS2_k127_4835416_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001828 248.0
TLS2_k127_4835416_6 Peptidase M50B-like - - - 0.000000000000000000000000000000000000000000000000000000000000005313 225.0
TLS2_k127_4835416_7 Bacterial flagellin C-terminal helical region K02397 - - 0.0000000000000000000000000000000000000000000000000000002628 204.0
TLS2_k127_4835416_9 flagellar protein FliS K02422 - - 0.0000000000000000000000000000000001227 137.0
TLS2_k127_485235_0 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 583.0
TLS2_k127_485235_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 589.0
TLS2_k127_485235_2 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 555.0
TLS2_k127_485235_3 glycine cleavage system K00605 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 502.0
TLS2_k127_485235_4 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000001085 196.0
TLS2_k127_485235_5 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000002968 210.0
TLS2_k127_485235_6 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000001096 207.0
TLS2_k127_485235_7 membrane - GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.000000000000000000000000000000000000000004053 171.0
TLS2_k127_485235_8 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity K00768 - 2.4.2.21 0.00000000000000000000000000000000002096 150.0
TLS2_k127_485235_9 - - - - 0.00000000000000000000000002155 110.0
TLS2_k127_4857153_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1558.0
TLS2_k127_4857153_1 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0 1148.0
TLS2_k127_4857153_10 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 340.0
TLS2_k127_4857153_11 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 342.0
TLS2_k127_4857153_12 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 298.0
TLS2_k127_4857153_13 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001914 299.0
TLS2_k127_4857153_14 Sh3 type 3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002081 232.0
TLS2_k127_4857153_15 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000001028 213.0
TLS2_k127_4857153_16 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000005761 218.0
TLS2_k127_4857153_17 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000002929 214.0
TLS2_k127_4857153_18 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000000000004821 190.0
TLS2_k127_4857153_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000001827 173.0
TLS2_k127_4857153_2 WD domain, G-beta repeat - - - 0.0 1069.0
TLS2_k127_4857153_20 - - - - 0.00000000000000000000000000000000001506 146.0
TLS2_k127_4857153_21 - - - - 0.000000000000459 83.0
TLS2_k127_4857153_22 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.000000000005079 68.0
TLS2_k127_4857153_23 HNH nucleases - - - 0.00000000006736 65.0
TLS2_k127_4857153_24 - - - - 0.00000001275 62.0
TLS2_k127_4857153_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.249e-286 892.0
TLS2_k127_4857153_4 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 1.277e-221 713.0
TLS2_k127_4857153_5 Transcriptional regulator K03655,K10439,K11708 - 3.6.4.12 1.06e-216 691.0
TLS2_k127_4857153_6 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 565.0
TLS2_k127_4857153_7 Glutathionylspermidine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 430.0
TLS2_k127_4857153_8 membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 402.0
TLS2_k127_4857153_9 ubiE/COQ5 methyltransferase family K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 382.0
TLS2_k127_4864798_0 PFAM regulatory protein LuxR - - - 0.0 1171.0
TLS2_k127_4864798_1 Peptidase S9 prolyl oligopeptidase active site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 565.0
TLS2_k127_4864798_10 - - - - 0.000002807 51.0
TLS2_k127_4864798_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 452.0
TLS2_k127_4864798_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 340.0
TLS2_k127_4864798_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000009104 222.0
TLS2_k127_4864798_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.0000000000000000000000000000000000000000000000000000000007058 209.0
TLS2_k127_4864798_6 PFAM Bacterial membrane flanked domain - - - 0.00000000000000000000000000000000000000000000000000008682 192.0
TLS2_k127_4864798_7 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000003633 207.0
TLS2_k127_4864798_8 - - - - 0.0000000000000000000000000001903 124.0
TLS2_k127_4864798_9 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000001401 118.0
TLS2_k127_4868347_0 reductase K17829 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043880,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363 1.3.1.86 1.32e-244 763.0
TLS2_k127_4868347_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0075136,GO:1901575 2.3.1.9 1.88e-196 622.0
TLS2_k127_4868347_2 Cellulose-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 481.0
TLS2_k127_4868347_3 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 371.0
TLS2_k127_4868347_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000001106 239.0
TLS2_k127_4896055_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.0 2308.0
TLS2_k127_4896055_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.0 2003.0
TLS2_k127_4896055_10 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 537.0
TLS2_k127_4896055_11 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 460.0
TLS2_k127_4896055_12 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 406.0
TLS2_k127_4896055_13 Methionine aminopeptidase K01265 GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 379.0
TLS2_k127_4896055_14 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 383.0
TLS2_k127_4896055_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 369.0
TLS2_k127_4896055_16 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 357.0
TLS2_k127_4896055_17 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 351.0
TLS2_k127_4896055_18 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 344.0
TLS2_k127_4896055_19 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 336.0
TLS2_k127_4896055_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1234.0
TLS2_k127_4896055_20 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 331.0
TLS2_k127_4896055_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 299.0
TLS2_k127_4896055_22 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 287.0
TLS2_k127_4896055_23 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000798 269.0
TLS2_k127_4896055_24 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008136 261.0
TLS2_k127_4896055_25 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001213 257.0
TLS2_k127_4896055_26 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001872 252.0
TLS2_k127_4896055_27 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000009052 248.0
TLS2_k127_4896055_28 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000004548 244.0
TLS2_k127_4896055_29 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000006291 246.0
TLS2_k127_4896055_3 pyridine K00322 - 1.6.1.1 3.837e-241 755.0
TLS2_k127_4896055_30 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000345 251.0
TLS2_k127_4896055_31 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000002682 254.0
TLS2_k127_4896055_32 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000002756 241.0
TLS2_k127_4896055_33 ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000003154 243.0
TLS2_k127_4896055_34 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000002024 232.0
TLS2_k127_4896055_35 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000021 225.0
TLS2_k127_4896055_36 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002704 208.0
TLS2_k127_4896055_37 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000000000000000004744 187.0
TLS2_k127_4896055_38 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000005367 195.0
TLS2_k127_4896055_39 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000572 186.0
TLS2_k127_4896055_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 3.454e-231 722.0
TLS2_k127_4896055_40 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000000000000003546 186.0
TLS2_k127_4896055_41 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000009812 178.0
TLS2_k127_4896055_42 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001996 175.0
TLS2_k127_4896055_43 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000287 159.0
TLS2_k127_4896055_44 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944 - 0.00000000000000000000000000000000000000002966 154.0
TLS2_k127_4896055_45 TM2 domain - - - 0.000000000000000000000000000000000000003236 152.0
TLS2_k127_4896055_47 - - - - 0.00000000000000000000000000000000002421 140.0
TLS2_k127_4896055_48 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000005269 126.0
TLS2_k127_4896055_49 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000005394 125.0
TLS2_k127_4896055_5 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 1.327e-211 667.0
TLS2_k127_4896055_50 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000001677 93.0
TLS2_k127_4896055_51 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000001845 90.0
TLS2_k127_4896055_52 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000002941 96.0
TLS2_k127_4896055_53 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000006467 77.0
TLS2_k127_4896055_54 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000001982 75.0
TLS2_k127_4896055_55 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000001696 50.0
TLS2_k127_4896055_6 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 2.684e-206 650.0
TLS2_k127_4896055_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 2.553e-201 638.0
TLS2_k127_4896055_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0008150,GO:0040007 5.4.2.10 4.82e-200 639.0
TLS2_k127_4896055_9 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 603.0
TLS2_k127_4922891_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.0 1022.0
TLS2_k127_4922891_1 Dehydrogenase K00074 - 1.1.1.157 1.793e-282 878.0
TLS2_k127_4922891_2 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 390.0
TLS2_k127_4922891_3 Aminotransferase class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 375.0
TLS2_k127_4922891_4 Glycine D-amino acid oxidases (deaminating) K00273 - 1.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 325.0
TLS2_k127_4922891_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000006413 204.0
TLS2_k127_4922891_6 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000000001126 180.0
TLS2_k127_4922891_7 FecR protein - - - 0.0002141 54.0
TLS2_k127_4924312_0 proteasome accessory factor PafA2 K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 1.514e-272 844.0
TLS2_k127_4924312_1 AAA ATPase forming ring-shaped complexes K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 582.0
TLS2_k127_4924312_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 402.0
TLS2_k127_4924312_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 398.0
TLS2_k127_4924312_4 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 396.0
TLS2_k127_4924312_5 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000005517 201.0
TLS2_k127_4924312_6 Protein of unknown function (DUF3054) - - - 0.0000000000000000000002264 102.0
TLS2_k127_4924312_7 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 - - 0.0000000000000000006303 89.0
TLS2_k127_4932086_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 1.008e-256 808.0
TLS2_k127_4932086_1 N-terminal domain of (some) glycogen debranching enzymes - - - 2.895e-216 692.0
TLS2_k127_4932086_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 460.0
TLS2_k127_4932086_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 420.0
TLS2_k127_4932086_4 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 291.0
TLS2_k127_4932086_5 Histidine kinase - - - 0.00000000008224 75.0
TLS2_k127_4950732_0 Class II Aldolase and Adducin N-terminal domain K01845 - 5.4.3.8 2.244e-224 703.0
TLS2_k127_4950732_1 Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 492.0
TLS2_k127_4950732_2 PucR C-terminal helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 443.0
TLS2_k127_4950732_3 Transposase - - - 0.00000003488 55.0
TLS2_k127_4954113_0 protein, coenzyme F420 biosynthesis associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 474.0
TLS2_k127_4954113_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 348.0
TLS2_k127_4954113_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 339.0
TLS2_k127_4954113_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 304.0
TLS2_k127_5008238_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.295e-284 887.0
TLS2_k127_5008238_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 482.0
TLS2_k127_5008238_2 PFAM aminotransferase class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 425.0
TLS2_k127_5008238_3 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are - - - 0.00000000000000005709 85.0
TLS2_k127_5059236_0 ABC transporter K15738 - - 2.46e-255 803.0
TLS2_k127_5059236_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 370.0
TLS2_k127_5059236_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 368.0
TLS2_k127_5059236_3 rare lipoprotein A K20628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001198 308.0
TLS2_k127_5059236_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04079 - - 0.00000000000000000000000000000000000000000000000000000000000000002819 229.0
TLS2_k127_5085403_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1667.0
TLS2_k127_5085403_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1080.0
TLS2_k127_5085403_10 PFAM binding-protein-dependent transport systems inner membrane component K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 384.0
TLS2_k127_5085403_11 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 350.0
TLS2_k127_5085403_12 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 336.0
TLS2_k127_5085403_13 phosphate transporter K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 315.0
TLS2_k127_5085403_14 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002288 292.0
TLS2_k127_5085403_15 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009383 271.0
TLS2_k127_5085403_16 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001938 249.0
TLS2_k127_5085403_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005001 262.0
TLS2_k127_5085403_18 May play a role in the intracellular transport of hydrophobic ligands - - - 0.000000000000000000000000000000000000000000000000000000000000004799 221.0
TLS2_k127_5085403_19 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000002959 168.0
TLS2_k127_5085403_2 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 516.0
TLS2_k127_5085403_20 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000000000005923 154.0
TLS2_k127_5085403_21 InterPro IPR014922 - - - 0.00000000000000000000000000000000001159 142.0
TLS2_k127_5085403_22 Thioredoxin - - - 0.0000000000000000000000000000000002691 140.0
TLS2_k127_5085403_23 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000005571 140.0
TLS2_k127_5085403_24 - - - - 0.000000000000000000000000000573 128.0
TLS2_k127_5085403_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 448.0
TLS2_k127_5085403_4 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 441.0
TLS2_k127_5085403_5 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 447.0
TLS2_k127_5085403_6 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 419.0
TLS2_k127_5085403_7 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 416.0
TLS2_k127_5085403_8 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 GO:0002682,GO:0002683,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0015698,GO:0016020,GO:0016036,GO:0030312,GO:0031347,GO:0031348,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035821,GO:0040007,GO:0042594,GO:0043207,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0044464,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071496,GO:0071944,GO:0075136,GO:0080134 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 390.0
TLS2_k127_5085403_9 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 376.0
TLS2_k127_5105883_0 Putative type VII ESX secretion system translocon, EccE - - - 0.000000000000000000000000000000000000000000000000000000000000000000475 246.0
TLS2_k127_5105883_1 - - - - 0.0000000000000000000000000000000000000000000000000000000001462 221.0
TLS2_k127_5113546_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0 1332.0
TLS2_k127_5113546_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 527.0
TLS2_k127_5113546_10 Ribosomal protein S1 K02945 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000002708 227.0
TLS2_k127_5113546_11 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000001796 140.0
TLS2_k127_5113546_12 DNA-binding transcription factor activity - - - 0.00007825 53.0
TLS2_k127_5113546_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 526.0
TLS2_k127_5113546_3 Catalyzes the formation of phosphoenolpyruvate from pyruvate K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 469.0
TLS2_k127_5113546_4 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 404.0
TLS2_k127_5113546_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 376.0
TLS2_k127_5113546_6 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 366.0
TLS2_k127_5113546_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 366.0
TLS2_k127_5113546_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 343.0
TLS2_k127_5113546_9 response regulator K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 315.0
TLS2_k127_5155702_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 518.0
TLS2_k127_5155702_1 Peptidase S8 and S53 subtilisin kexin sedolisin K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 418.0
TLS2_k127_5155702_2 uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 357.0
TLS2_k127_5155702_3 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 303.0
TLS2_k127_5155702_4 PadR family transcriptional regulator K10947 - - 0.00000000000000000000000000000000000000000000000002082 181.0
TLS2_k127_5155702_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000004348 177.0
TLS2_k127_5155702_6 O-acyltransferase activity K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000005663 181.0
TLS2_k127_5155702_7 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000001282 170.0
TLS2_k127_5155702_8 membrane - - - 0.0000000000000000000000000000000002958 148.0
TLS2_k127_5155702_9 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0000000001044 73.0
TLS2_k127_5234106_0 Belongs to the GcvT family K19191 - 1.5.3.19 0.0 1348.0
TLS2_k127_5234106_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 590.0
TLS2_k127_5234106_12 - - - - 0.0006972 44.0
TLS2_k127_5234106_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 366.0
TLS2_k127_5234106_3 Serine acetyltransferase, N-terminal K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 353.0
TLS2_k127_5234106_4 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 344.0
TLS2_k127_5234106_5 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 310.0
TLS2_k127_5234106_6 Belongs to the serpin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003628 296.0
TLS2_k127_5234106_7 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005531 267.0
TLS2_k127_5234106_8 - - - - 0.000000000000000000000000000000000000000000000000000003708 201.0
TLS2_k127_5234106_9 - - - - 0.0000000000000000000009722 98.0
TLS2_k127_5262902_0 PFAM FAD linked oxidase domain protein - - - 4.768e-219 691.0
TLS2_k127_5262902_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 3.31e-212 664.0
TLS2_k127_5262902_11 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00002461 49.0
TLS2_k127_5262902_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.1.1.79 1.319e-205 651.0
TLS2_k127_5262902_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 595.0
TLS2_k127_5262902_4 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 544.0
TLS2_k127_5262902_5 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 454.0
TLS2_k127_5262902_6 nuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000584 244.0
TLS2_k127_5262902_7 Carbonic anhydrase K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000218 228.0
TLS2_k127_5262902_8 Peptidase family S51 - - - 0.00000000000000000000000000000000000000000000000000000000296 210.0
TLS2_k127_5262902_9 Aminoglycoside phosphotransferase K16146 - 2.7.1.175 0.000000000000000000000000000000000000000000000000000000005036 217.0
TLS2_k127_5277450_0 Acetyl-CoA carboxylase, central region - - - 0.0 2353.0
TLS2_k127_5343523_0 but shows high identity with sulfide-quinone reductase from chlorobium tepidum K17218 - 1.8.5.4 1.61e-225 710.0
TLS2_k127_5343523_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 598.0
TLS2_k127_5343523_2 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001367 259.0
TLS2_k127_5343523_3 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000233 165.0
TLS2_k127_5343523_4 Sensory domain found in PocR K07315 - 3.1.3.3 0.000000000000000000000000000004215 129.0
TLS2_k127_5343523_5 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000000002878 123.0
TLS2_k127_5343523_6 Protein of unknown function (DUF1641) - - - 0.00005266 55.0
TLS2_k127_5343523_7 - - - - 0.000186 48.0
TLS2_k127_5378018_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 0.0 1019.0
TLS2_k127_5378018_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 9.374e-204 642.0
TLS2_k127_5378018_10 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000001945 260.0
TLS2_k127_5378018_11 Aminoacyl-tRNA editing domain K03976 - - 0.000000000000000000000000000000000000000000000000000000000008041 215.0
TLS2_k127_5378018_12 Uncharacterised protein family (UPF0014) K02069 - - 0.0000000000000000000000000000000000000000000000003218 192.0
TLS2_k127_5378018_13 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000000000000000000000009552 156.0
TLS2_k127_5378018_14 - - - - 0.00000002214 60.0
TLS2_k127_5378018_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 1.067e-201 639.0
TLS2_k127_5378018_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 543.0
TLS2_k127_5378018_4 Glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 542.0
TLS2_k127_5378018_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814,K01817 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 416.0
TLS2_k127_5378018_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 341.0
TLS2_k127_5378018_7 Imidazoleglycerol-phosphate dehydratase K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 318.0
TLS2_k127_5378018_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 317.0
TLS2_k127_5378018_9 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 313.0
TLS2_k127_54189_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 3.982e-268 835.0
TLS2_k127_54189_1 ABC transporter transmembrane region - - - 1.031e-221 711.0
TLS2_k127_54189_10 protein import - - - 0.000000000000000000000000000000000000000000000000000000002762 209.0
TLS2_k127_54189_11 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000008957 207.0
TLS2_k127_54189_12 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000003343 146.0
TLS2_k127_54189_13 - - - - 0.000000000000000000000000000000268 129.0
TLS2_k127_54189_14 LysR substrate binding domain - - - 0.0000000000000000000000000004303 125.0
TLS2_k127_54189_15 Psort location Cytoplasmic, score - - - 0.00000000000000000000000006664 124.0
TLS2_k127_54189_16 Domain of unknown function (DUF3817) - - - 0.00000000000000000000000009121 110.0
TLS2_k127_54189_17 transcriptional - - - 0.000000000000000002711 98.0
TLS2_k127_54189_2 Belongs to the aldehyde dehydrogenase family K00135 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009013,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 607.0
TLS2_k127_54189_3 Sodium:sulfate symporter transmembrane region K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 565.0
TLS2_k127_54189_4 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 556.0
TLS2_k127_54189_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 324.0
TLS2_k127_54189_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 312.0
TLS2_k127_54189_7 KR domain K00218 - 1.3.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008295 291.0
TLS2_k127_54189_8 Nucleotidyl transferase K00966,K00992 - 2.7.7.13,2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001659 288.0
TLS2_k127_54189_9 SURF1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000004053 224.0
TLS2_k127_5430623_0 Protein of unknown function (DUF3029) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 590.0
TLS2_k127_5430623_1 amidohydrolase K01436,K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 464.0
TLS2_k127_5430623_2 basic membrane K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 416.0
TLS2_k127_5430623_3 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000001075 218.0
TLS2_k127_5430623_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000002607 209.0
TLS2_k127_5430623_5 4 iron, 4 sulfur cluster binding - - - 0.0007654 48.0
TLS2_k127_5432259_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 602.0
TLS2_k127_5432259_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 492.0
TLS2_k127_5432259_2 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001931 294.0
TLS2_k127_5432259_3 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000001508 226.0
TLS2_k127_5432259_4 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000006461 159.0
TLS2_k127_5438478_0 Adenosine deaminase K01488 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 510.0
TLS2_k127_5438478_1 cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 485.0
TLS2_k127_5438478_10 2'-5' RNA ligase superfamily - - - 0.00003972 53.0
TLS2_k127_5438478_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 405.0
TLS2_k127_5438478_3 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 373.0
TLS2_k127_5438478_4 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 325.0
TLS2_k127_5438478_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008035 255.0
TLS2_k127_5438478_6 Belongs to the UPF0336 family - - - 0.00000000000000000000000000000000000000000000000000000000000001186 218.0
TLS2_k127_5438478_7 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000004284 213.0
TLS2_k127_5438478_8 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000001121 212.0
TLS2_k127_5438478_9 - - - - 0.00000000000000000000000000000000000000000000000000475 207.0
TLS2_k127_547659_0 Vault protein inter-alpha-trypsin domain K07114 - - 3.419e-241 773.0
TLS2_k127_547659_1 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 440.0
TLS2_k127_547659_2 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 415.0
TLS2_k127_547659_4 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000001666 138.0
TLS2_k127_5494789_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 559.0
TLS2_k127_5494789_1 Acetyl xylan esterase (AXE1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 349.0
TLS2_k127_5494789_2 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 291.0
TLS2_k127_5494789_3 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06131 - - 0.0000000000000000000000000000000000000000000000000001747 210.0
TLS2_k127_5497405_0 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 359.0
TLS2_k127_5497405_1 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 314.0
TLS2_k127_5497405_2 Inorganic pyrophosphatase K01507 GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 291.0
TLS2_k127_5497405_3 PFAM NLP P60 protein K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001213 290.0
TLS2_k127_5497405_4 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000004741 232.0
TLS2_k127_5516039_0 Belongs to the helicase family. UvrD subfamily - - - 0.0 1218.0
TLS2_k127_5516039_1 Belongs to the helicase family. UvrD subfamily K03657 - 3.6.4.12 0.0 1214.0
TLS2_k127_5516039_10 Glutaredoxin K18917 - 1.20.4.3 0.0000000000000000000000000000000000001872 146.0
TLS2_k127_5516039_11 HD domain - - - 0.00000000000000000000000000000000001052 141.0
TLS2_k127_5516039_2 DNA helicase K03657 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 4.22e-279 880.0
TLS2_k127_5516039_3 Drug exporters of the RND superfamily K06994 - - 2.035e-239 761.0
TLS2_k127_5516039_4 NADH pyrophosphatase K03426 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 347.0
TLS2_k127_5516039_5 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 344.0
TLS2_k127_5516039_6 endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000005145 219.0
TLS2_k127_5516039_7 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18958 - - 0.000000000000000000000000000000000000000004037 159.0
TLS2_k127_5516039_8 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.00000000000000000000000000000000000000001449 156.0
TLS2_k127_5516039_9 uridine kinase - - - 0.000000000000000000000000000000000000003 158.0
TLS2_k127_5521519_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 1.587e-227 727.0
TLS2_k127_5521519_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 381.0
TLS2_k127_5521519_2 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000009011 229.0
TLS2_k127_5521519_3 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.0000000000000000000000000000000000000000000000000000000136 216.0
TLS2_k127_5521519_4 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000002477 172.0
TLS2_k127_5531764_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 5e-324 1012.0
TLS2_k127_5531764_1 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 3.456e-212 670.0
TLS2_k127_5531764_10 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 295.0
TLS2_k127_5531764_11 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 312.0
TLS2_k127_5531764_12 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000102 250.0
TLS2_k127_5531764_13 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002528 201.0
TLS2_k127_5531764_14 ACT domain K09707 - - 0.0000000000000000000000000000000000000031 155.0
TLS2_k127_5531764_15 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000001018 107.0
TLS2_k127_5531764_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 595.0
TLS2_k127_5531764_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 569.0
TLS2_k127_5531764_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 527.0
TLS2_k127_5531764_5 acetylornithine aminotransferase K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 520.0
TLS2_k127_5531764_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 485.0
TLS2_k127_5531764_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 450.0
TLS2_k127_5531764_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 347.0
TLS2_k127_5531764_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 329.0
TLS2_k127_5549451_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 423.0
TLS2_k127_5549451_1 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 318.0
TLS2_k127_5549451_2 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 307.0
TLS2_k127_5549451_3 Response regulator receiver K07696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 302.0
TLS2_k127_5549451_4 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000001688 93.0
TLS2_k127_5549451_5 PFAM Transglycosylase associated protein - - - 0.0004054 48.0
TLS2_k127_5551300_0 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1058.0
TLS2_k127_5551300_1 - - - - 7.924e-224 701.0
TLS2_k127_5551300_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004762 254.0
TLS2_k127_5551300_11 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000415 261.0
TLS2_k127_5551300_12 Histidine kinase K07778 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000001788 231.0
TLS2_k127_5551300_13 Domain of unknown function (DUF4142) - - - 0.0000000000000000000000000000000000000000000000000002205 200.0
TLS2_k127_5551300_14 Transcriptional regulator PadR family protein - - - 0.0000000000000000000000000000000000000000000000000002411 187.0
TLS2_k127_5551300_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000004931 181.0
TLS2_k127_5551300_16 phosphoglycerate mutase - - - 0.000000000000000000000000000000004347 139.0
TLS2_k127_5551300_17 Domain of unkown function (DUF1775) - - - 0.000000000000000000000000000000005745 138.0
TLS2_k127_5551300_18 chemotaxis K03406 - - 0.00000000000000000002577 97.0
TLS2_k127_5551300_2 Binding-protein-dependent transport system inner membrane component K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 471.0
TLS2_k127_5551300_3 Sulphur oxygenase reductase K16952 - 1.13.11.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 472.0
TLS2_k127_5551300_4 PFAM periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 459.0
TLS2_k127_5551300_5 Binding-protein-dependent transport system inner membrane component K02026,K10119,K17243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 449.0
TLS2_k127_5551300_6 Voltage-dependent anion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 425.0
TLS2_k127_5551300_7 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 296.0
TLS2_k127_5551300_8 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001658 290.0
TLS2_k127_5551300_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002281 260.0
TLS2_k127_557605_0 aminopeptidase N K01256,K08776 - 3.4.11.2 0.0 1167.0
TLS2_k127_557605_1 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 380.0
TLS2_k127_557605_10 histidine kinase HAMP region domain protein K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000004242 197.0
TLS2_k127_557605_11 belongs to the urease gamma subunit family K14048 - 3.5.1.5 0.000000000000000000000000000000000000008367 147.0
TLS2_k127_557605_12 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000003065 81.0
TLS2_k127_557605_2 Sterol carrier protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 387.0
TLS2_k127_557605_3 DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 321.0
TLS2_k127_557605_4 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 327.0
TLS2_k127_557605_5 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 287.0
TLS2_k127_557605_6 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 259.0
TLS2_k127_557605_7 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001846 264.0
TLS2_k127_557605_8 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000848 241.0
TLS2_k127_557605_9 Protein of unknown function (DUF429) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008817 245.0
TLS2_k127_5599050_0 Protein kinase G tetratricopeptide repeat K14949 - 2.7.11.1 1.146e-319 999.0
TLS2_k127_5599050_1 Bifunctional purine biosynthesis protein PurH K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 2.376e-255 796.0
TLS2_k127_5599050_10 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000302 273.0
TLS2_k127_5599050_11 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000562 280.0
TLS2_k127_5599050_12 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003265 259.0
TLS2_k127_5599050_13 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001404 245.0
TLS2_k127_5599050_14 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000000000000000000000000000000000000000000001692 218.0
TLS2_k127_5599050_15 - - - - 0.0000000000000000000000000000000000000000000000000000006559 198.0
TLS2_k127_5599050_16 phosphoserine phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000006395 208.0
TLS2_k127_5599050_2 von willebrand factor type a - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 589.0
TLS2_k127_5599050_3 Toxic anion resistance protein (TelA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 575.0
TLS2_k127_5599050_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 501.0
TLS2_k127_5599050_5 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 461.0
TLS2_k127_5599050_6 transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 400.0
TLS2_k127_5599050_7 PAS fold domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 394.0
TLS2_k127_5599050_8 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 314.0
TLS2_k127_5599050_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 306.0
TLS2_k127_5608062_0 Alcohol dehydrogenase GroES-like domain K00148 - 1.2.1.46 1.249e-205 655.0
TLS2_k127_5608062_1 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 513.0
TLS2_k127_5608062_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 332.0
TLS2_k127_5608062_3 Virulence factor BrkB - - - 0.000000000000000000000000000000000000000000000000003707 190.0
TLS2_k127_5608062_4 HlyD family secretion protein K02005,K13888 - - 0.000000000000000000000000000007004 137.0
TLS2_k127_5608062_5 Cyclase dehydrase - - - 0.00000000000000000000000003338 117.0
TLS2_k127_5608062_6 - - - - 0.0000000007007 67.0
TLS2_k127_5608062_8 - - - - 0.000000126 56.0
TLS2_k127_5622099_0 phytoene K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 4.292e-241 753.0
TLS2_k127_5622099_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 434.0
TLS2_k127_5622099_2 phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 425.0
TLS2_k127_5622099_3 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 422.0
TLS2_k127_5622099_4 Pfam CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000005613 194.0
TLS2_k127_5656694_0 EamA-like transporter family K11939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 396.0
TLS2_k127_5656694_1 CHAD domain containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 341.0
TLS2_k127_5656694_2 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 299.0
TLS2_k127_5656694_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000003926 173.0
TLS2_k127_5656694_4 Domain of unknown function (DUF4259) - - - 0.00000000000000000000000000000000000000197 153.0
TLS2_k127_5710172_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K13540,K13541 - 2.1.1.130,2.1.1.131,3.7.1.12 5.118e-236 753.0
TLS2_k127_5710172_1 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 554.0
TLS2_k127_5710172_2 Uroporphyrin-III C-methyltransferase K03795 - 4.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 504.0
TLS2_k127_5710172_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 498.0
TLS2_k127_5710172_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 487.0
TLS2_k127_5710172_5 High-affinity nickel-transport protein K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 461.0
TLS2_k127_5710172_6 Tetrapyrrole (Corrin/Porphyrin) Methylases K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 445.0
TLS2_k127_5710172_7 Tetrapyrrole (Corrin/Porphyrin) Methylases K03394 - 2.1.1.130,2.1.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 311.0
TLS2_k127_5710172_8 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000000000000000000000000004572 274.0
TLS2_k127_5735458_0 polyketide synthase K12437,K12443 - - 0.0 1748.0
TLS2_k127_5735458_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 7.739e-215 688.0
TLS2_k127_5735458_10 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000003547 231.0
TLS2_k127_5735458_11 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000002499 218.0
TLS2_k127_5735458_12 oxidoreductase K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 0.00000000000000000000000000000000000000000000000000000009651 202.0
TLS2_k127_5735458_13 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000001526 169.0
TLS2_k127_5735458_14 - - - - 0.00000000000000000000000000000000000000000003467 169.0
TLS2_k127_5735458_15 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000001499 176.0
TLS2_k127_5735458_16 CopC domain - - - 0.00002095 56.0
TLS2_k127_5735458_2 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 2.305e-203 640.0
TLS2_k127_5735458_3 AMP-binding enzyme K00666,K12423,K12425,K12426,K12427,K12428,K21059 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0004321,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006790,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0019751,GO:0019752,GO:0022607,GO:0030312,GO:0031347,GO:0031348,GO:0032787,GO:0034311,GO:0034312,GO:0035821,GO:0040007,GO:0042546,GO:0042844,GO:0042845,GO:0043207,GO:0043436,GO:0044003,GO:0044085,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0044464,GO:0045088,GO:0045824,GO:0046165,GO:0046173,GO:0046394,GO:0046505,GO:0046506,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0070566,GO:0071554,GO:0071704,GO:0071766,GO:0071769,GO:0071770,GO:0071840,GO:0071944,GO:0072330,GO:0075136,GO:0080134,GO:0097040,GO:1901576,GO:1901615,GO:1901617 2.7.7.95,6.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 496.0
TLS2_k127_5735458_4 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 449.0
TLS2_k127_5735458_5 Secretory lipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 384.0
TLS2_k127_5735458_6 Major facilitator superfamily K08170 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 364.0
TLS2_k127_5735458_7 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 326.0
TLS2_k127_5735458_8 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003029 298.0
TLS2_k127_5735458_9 Forkhead associated domain K01990,K21397 - - 0.00000000000000000000000000000000000000000000000000000000000000001245 248.0
TLS2_k127_5745554_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - 0.0 1624.0
TLS2_k127_5745554_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 0.0 1178.0
TLS2_k127_5745554_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 431.0
TLS2_k127_5745554_3 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 386.0
TLS2_k127_5745554_4 Zn-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 310.0
TLS2_k127_5745554_5 EamA-like transporter family K03298 - - 0.0000000000000000000000000000000000000000000000000000000000002833 225.0
TLS2_k127_5745554_6 Mycothiol maleylpyruvate isomerase N-terminal domain K16163 - 5.2.1.4 0.000000000000000000000000000000000000000003074 164.0
TLS2_k127_5759628_0 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0 1703.0
TLS2_k127_5792803_0 radical SAM K06871 - - 2.458e-212 675.0
TLS2_k127_5792803_1 penicillin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 616.0
TLS2_k127_5792803_10 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000006966 226.0
TLS2_k127_5792803_11 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000005267 229.0
TLS2_k127_5792803_12 Glycosyl hydrolases family 25 K07273 - - 0.00000000000000000000000000000000000000000000000000006343 201.0
TLS2_k127_5792803_13 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.0000000000000000000000000000000000000000003202 162.0
TLS2_k127_5792803_14 Domain of unknown function (DUF4177) - - - 0.0000000000000000000006793 104.0
TLS2_k127_5792803_15 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000004197 100.0
TLS2_k127_5792803_16 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K03556 - - 0.000000000000388 79.0
TLS2_k127_5792803_2 anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 575.0
TLS2_k127_5792803_3 Pfam Anion-transporting ATPase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 466.0
TLS2_k127_5792803_4 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 441.0
TLS2_k127_5792803_5 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 404.0
TLS2_k127_5792803_6 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 407.0
TLS2_k127_5792803_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 379.0
TLS2_k127_5792803_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 330.0
TLS2_k127_5792803_9 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002497 244.0
TLS2_k127_5798433_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 8.377e-230 734.0
TLS2_k127_5798433_1 homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 2.648e-196 621.0
TLS2_k127_5798433_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 569.0
TLS2_k127_5798433_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 314.0
TLS2_k127_5798916_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 513.0
TLS2_k127_5798916_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 419.0
TLS2_k127_5798916_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 378.0
TLS2_k127_5798916_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000000000000007296 195.0
TLS2_k127_5798916_4 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000000000000000002939 132.0
TLS2_k127_5798916_5 Recombinase - - - 0.000000000000000000000003188 111.0
TLS2_k127_5798916_6 TIGRFAM YD repeat protein - - - 0.0000000002506 64.0
TLS2_k127_5798916_7 Insecticide toxin TcdB middle/N-terminal region - - - 0.0000000009745 69.0
TLS2_k127_5798916_8 lipolytic protein G-D-S-L family - - - 0.0000004367 57.0
TLS2_k127_5798916_9 Recombinase - - - 0.00002938 53.0
TLS2_k127_5813647_0 DNA-binding transcriptional activator of the SARP family - - - 0.00000000000000000000000000000000000000000000004853 183.0
TLS2_k127_5813647_2 HD domain - - - 0.00000000000000000000000000000007954 130.0
TLS2_k127_5813647_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0002243 51.0
TLS2_k127_5814355_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.61e-252 784.0
TLS2_k127_5814355_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 1.436e-200 629.0
TLS2_k127_5814355_2 N-terminal Region. This family is found at the N-terminus of a number of subtilisins. It is cleaved prior to activation of the enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 639.0
TLS2_k127_5814355_3 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 470.0
TLS2_k127_5814355_4 transport, permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 351.0
TLS2_k127_5814355_5 transport, permease protein K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000002619 253.0
TLS2_k127_5814355_6 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000002159 185.0
TLS2_k127_5814355_7 Subtilisin inhibitor-like - - - 0.000000000000000000000000000127 124.0
TLS2_k127_5830982_0 Poly(3-hydroxybutyrate) depolymerase - - - 6.751e-256 803.0
TLS2_k127_5830982_1 PFAM glycoside hydrolase, family 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 608.0
TLS2_k127_5830982_2 Poly(3-hydroxybutyrate) depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 552.0
TLS2_k127_5830982_3 FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 459.0
TLS2_k127_5830982_4 COG1073 Hydrolases of the alpha beta superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 305.0
TLS2_k127_5830982_5 PFAM glycoside hydrolase, family 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 283.0
TLS2_k127_5830982_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000001279 231.0
TLS2_k127_5830982_7 Transposase, mutator K07493 - - 0.0000000000000000000000000000002942 126.0
TLS2_k127_5846917_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 512.0
TLS2_k127_5846917_1 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 368.0
TLS2_k127_5846917_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001104 304.0
TLS2_k127_5846917_3 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000003835 181.0
TLS2_k127_5846917_4 OmpA family - - - 0.00000000000000000000000000000000000000000005776 181.0
TLS2_k127_5846917_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000001768 161.0
TLS2_k127_5846917_6 Helix-hairpin-helix domain - - - 0.00000000000000000000000000000000000000991 161.0
TLS2_k127_5846917_7 HNH nucleases K07451 - - 0.000000000000000000000000000000000006388 145.0
TLS2_k127_5846917_8 Protein of unknown function (DUF2530) - - - 0.0000000000004289 72.0
TLS2_k127_5848664_0 DNA polymerase alpha chain like domain K02337 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 2.62e-294 914.0
TLS2_k127_5848664_1 Domain of unknown function (DUF4339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 451.0
TLS2_k127_5848664_2 sporulation resulting in formation of a cellular spore - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 460.0
TLS2_k127_5890615_0 Xanthine dehydrogenase K03520 - 1.2.5.3 0.0 1229.0
TLS2_k127_5890615_1 Nitrate reductase K02824 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 356.0
TLS2_k127_5890615_2 Molybdopterin dehydrogenase K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 340.0
TLS2_k127_5890615_3 [2Fe-2S] binding domain K03518,K19186 - 1.2.5.3,1.5.99.14 0.00000000000000000000000000000000000000000000000000000000000000000003382 250.0
TLS2_k127_5890615_4 carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000000000000000000000000000000000000001797 194.0
TLS2_k127_5897752_0 Belongs to the GARS family K01945,K11788 GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 591.0
TLS2_k127_5897752_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002895 270.0
TLS2_k127_5897752_2 - - - - 0.00000000000000000000000000000000000000000000000003516 186.0
TLS2_k127_5897752_3 lyase activity - - - 0.00000000000000000000001827 104.0
TLS2_k127_5897752_4 cyclase dehydrase - - - 0.00001191 54.0
TLS2_k127_5905898_0 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 5.782e-204 640.0
TLS2_k127_5905898_1 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 504.0
TLS2_k127_5905898_2 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 349.0
TLS2_k127_5905898_3 G-D-S-L family lipolytic protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009476 273.0
TLS2_k127_5905898_4 - - - - 0.000000000000000000000003974 106.0
TLS2_k127_5905898_5 glyoxalase III activity - - - 0.0000000000001179 70.0
TLS2_k127_5939803_0 ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 506.0
TLS2_k127_5939803_1 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 467.0
TLS2_k127_5939803_2 exporter of polyketide K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 442.0
TLS2_k127_5939803_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 329.0
TLS2_k127_5939803_4 response regulator - - - 0.000000000000000000000000000000000000000002228 170.0
TLS2_k127_5939803_5 Domain of unknown function (DUF305) - - - 0.00000000008804 64.0
TLS2_k127_5948128_0 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 588.0
TLS2_k127_5948128_1 flagellar motor switch protein FliG K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 454.0
TLS2_k127_5948128_2 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 437.0
TLS2_k127_5948128_3 cysteine-type peptidase activity K01183,K19303 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009254,GO:0016787,GO:0019538,GO:0030203,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901564 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 314.0
TLS2_k127_5948128_4 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000000000000000000000000000005487 198.0
TLS2_k127_5948128_5 bacterial-type flagellum organization K02411 - - 0.00000000000000000000000000000000001192 149.0
TLS2_k127_5948128_6 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000000000000002133 142.0
TLS2_k127_5948128_7 Flagellar hook-basal body complex protein FliE K02408 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.000000000000005831 85.0
TLS2_k127_5948926_0 Malic enzyme K00027 - 1.1.1.38 1.1e-211 669.0
TLS2_k127_5948926_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 552.0
TLS2_k127_5948926_2 Peptidase S8 and S53 subtilisin kexin sedolisin K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 410.0
TLS2_k127_5948926_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000562 289.0
TLS2_k127_5948926_4 regulation of translation - - - 0.000002193 56.0
TLS2_k127_5969404_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 571.0
TLS2_k127_5969404_1 cytochrome P450 K21164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 518.0
TLS2_k127_5969404_2 Histidinol phosphatase and related hydrolases of the PHP family K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 473.0
TLS2_k127_5969404_3 cell envelope-related transcriptional attenuator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 357.0
TLS2_k127_5969404_4 CHAD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 344.0
TLS2_k127_5969404_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000003758 164.0
TLS2_k127_5969404_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.00000000000000000001124 94.0
TLS2_k127_5969404_7 - - - - 0.000000000000001006 86.0
TLS2_k127_5969404_8 Universal stress protein - - - 0.000000000003924 76.0
TLS2_k127_5969404_9 Protein of unknown function (DUF3618) - - - 0.00000009861 61.0
TLS2_k127_5970899_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 0.0 1114.0
TLS2_k127_5970899_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 2.308e-249 806.0
TLS2_k127_5970899_2 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 535.0
TLS2_k127_5970899_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 381.0
TLS2_k127_5970899_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000001158 261.0
TLS2_k127_5970899_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000008578 208.0
TLS2_k127_5970899_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000002049 206.0
TLS2_k127_5970899_7 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000648 201.0
TLS2_k127_5970899_8 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000003577 194.0
TLS2_k127_5970899_9 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000001694 145.0
TLS2_k127_5973208_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 3.403e-273 844.0
TLS2_k127_5973208_1 Deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 549.0
TLS2_k127_5973208_10 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000002135 186.0
TLS2_k127_5973208_11 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000001839 124.0
TLS2_k127_5973208_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 537.0
TLS2_k127_5973208_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 449.0
TLS2_k127_5973208_4 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 379.0
TLS2_k127_5973208_5 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 368.0
TLS2_k127_5973208_6 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000373 267.0
TLS2_k127_5973208_7 Peptidase, M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001121 251.0
TLS2_k127_5973208_8 ATPases associated with a variety of cellular activities K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000001246 240.0
TLS2_k127_5973208_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000002996 226.0
TLS2_k127_59735_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1253.0
TLS2_k127_59735_1 DNA topoisomerase (ATP-hydrolyzing) K02470 - 5.99.1.3 0.0 1175.0
TLS2_k127_59735_10 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000001679 154.0
TLS2_k127_59735_11 - - - - 0.000000000000000000005451 100.0
TLS2_k127_59735_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 1.614e-217 680.0
TLS2_k127_59735_3 membrane protein terC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 499.0
TLS2_k127_59735_4 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 364.0
TLS2_k127_59735_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009198 340.0
TLS2_k127_59735_6 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003516 280.0
TLS2_k127_59735_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000001909 237.0
TLS2_k127_59735_8 Belongs to the peptidase S1B family - - - 0.0000000000000000000000000000000000000000000000000000000000695 218.0
TLS2_k127_59735_9 META domain K03668 - - 0.00000000000000000000000000000000000000000000000005354 189.0
TLS2_k127_6006862_0 Drug exporters of the RND superfamily K06994 - - 8.576e-268 845.0
TLS2_k127_6006862_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 382.0
TLS2_k127_6006862_2 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 337.0
TLS2_k127_6006862_3 Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related - - - 0.0000000000000000000000000000000000000413 156.0
TLS2_k127_6006862_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000002395 79.0
TLS2_k127_6006862_5 - - - - 0.000004109 53.0
TLS2_k127_6019295_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.096e-219 686.0
TLS2_k127_6019295_1 Glycosyl transferase 4-like domain K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 593.0
TLS2_k127_6019295_10 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003162 280.0
TLS2_k127_6019295_11 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007359 289.0
TLS2_k127_6019295_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 267.0
TLS2_k127_6019295_13 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000002537 211.0
TLS2_k127_6019295_14 Membrane-bound lytic murein transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000004781 217.0
TLS2_k127_6019295_15 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000003651 201.0
TLS2_k127_6019295_16 Nitroreductase - - - 0.000000000000000000000000000000000000000000000006658 186.0
TLS2_k127_6019295_17 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000000000000000000000001357 168.0
TLS2_k127_6019295_18 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000000001161 133.0
TLS2_k127_6019295_19 GGDEF domain - - - 0.000000000000000000000001852 117.0
TLS2_k127_6019295_2 phosphoserine phosphatase K01079 GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 507.0
TLS2_k127_6019295_3 prohibitin homologues - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 511.0
TLS2_k127_6019295_4 Major facilitator Superfamily K02445 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 419.0
TLS2_k127_6019295_5 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 409.0
TLS2_k127_6019295_6 Enoyl- acyl-carrier-protein reductase NADH K00208,K11611 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030312,GO:0030497,GO:0031406,GO:0032787,GO:0033293,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 407.0
TLS2_k127_6019295_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 423.0
TLS2_k127_6019295_8 reductase K00059,K11610 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0018454,GO:0019752,GO:0030497,GO:0032787,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046459,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070402,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 373.0
TLS2_k127_6019295_9 RRNA methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 368.0
TLS2_k127_6022083_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.057e-296 919.0
TLS2_k127_6022083_1 DNA polymerase family A K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 445.0
TLS2_k127_6022083_2 transmembrane signaling receptor activity K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 404.0
TLS2_k127_6022083_3 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.0000000000000000000000000000000000000000000000000000002598 210.0
TLS2_k127_6022083_4 Molybdopterin K03635 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.0000000000000000000000000000000000000000000000001646 181.0
TLS2_k127_6022083_5 transcriptional regulator - - - 0.000000000000000000000000000000000000001556 154.0
TLS2_k127_6024683_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001659 256.0
TLS2_k127_6024683_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001774 226.0
TLS2_k127_6024683_2 - - - - 0.000000000000000000000000000000000000007459 154.0
TLS2_k127_6024683_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000004762 87.0
TLS2_k127_6024683_4 - - - - 0.000000001629 67.0
TLS2_k127_6024683_5 - - - - 0.00000002701 64.0
TLS2_k127_6024683_6 - - - - 0.00000007446 61.0
TLS2_k127_6043424_0 helix-turn-helix- domain containing protein, AraC type K13529 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 3.098e-218 689.0
TLS2_k127_6043424_1 nitric oxide dioxygenase activity K00523,K15983 - 1.14.13.142,1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 599.0
TLS2_k127_6043424_2 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 476.0
TLS2_k127_6043424_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 417.0
TLS2_k127_6043424_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000623 257.0
TLS2_k127_6043424_5 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000101 216.0
TLS2_k127_6043424_6 FMN binding - - - 0.0000000000000000000000000000000000000002159 160.0
TLS2_k127_6043424_7 Pyridoxamine 5'-phosphate oxidase - - - 0.0000001884 58.0
TLS2_k127_6157081_0 Membrane protein TerC, possibly involved in tellurium resistance K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 374.0
TLS2_k127_6157081_1 TIGRFAM Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003481 265.0
TLS2_k127_6157081_2 domain protein - - - 0.000000000000000000000000000000000000000000000632 186.0
TLS2_k127_6157909_0 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 537.0
TLS2_k127_6157909_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 546.0
TLS2_k127_6157909_2 PFAM lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005289 286.0
TLS2_k127_6157909_3 Methyltransferase - - - 0.00000000000000000000000000000000000000000009832 168.0
TLS2_k127_6157909_4 Domain of unknown function (DUF1876) - - - 0.0000000000001532 76.0
TLS2_k127_6157909_5 - - - - 0.000001581 57.0
TLS2_k127_6213912_0 ABC transporter - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 3.249e-297 915.0
TLS2_k127_6213912_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 492.0
TLS2_k127_6213912_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 414.0
TLS2_k127_6213912_3 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000003646 164.0
TLS2_k127_6217610_0 O-acetylhomoserine K01740 - 2.5.1.49 1.346e-241 751.0
TLS2_k127_6217610_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 1.551e-212 671.0
TLS2_k127_6217610_10 Nudix hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000006402 192.0
TLS2_k127_6217610_11 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000007291 179.0
TLS2_k127_6217610_12 Domain of unknown function (DUF4192) - - - 0.00000000000000000000000000000000003192 149.0
TLS2_k127_6217610_13 ABC-2 family transporter protein - - - 0.00000000000000000000000000000004363 139.0
TLS2_k127_6217610_14 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000007667 117.0
TLS2_k127_6217610_15 - - - - 0.00000000000000000000000001541 119.0
TLS2_k127_6217610_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 594.0
TLS2_k127_6217610_3 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 541.0
TLS2_k127_6217610_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 367.0
TLS2_k127_6217610_5 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003478 279.0
TLS2_k127_6217610_6 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004969 280.0
TLS2_k127_6217610_7 PFAM HhH-GPD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007479 254.0
TLS2_k127_6217610_8 belongs to the sigma-70 factor family, ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000008235 209.0
TLS2_k127_6217610_9 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000009004 197.0
TLS2_k127_6219111_0 Belongs to the glycosyl hydrolase 26 family K01218 - 3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 485.0
TLS2_k127_6219111_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 392.0
TLS2_k127_6219111_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 259.0
TLS2_k127_6219111_3 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000009717 207.0
TLS2_k127_6219111_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000006208 132.0
TLS2_k127_622700_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K21397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 585.0
TLS2_k127_622700_1 Dyp-type peroxidase family K16301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008939 529.0
TLS2_k127_622700_10 transcriptional K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007996 270.0
TLS2_k127_622700_11 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000006125 194.0
TLS2_k127_622700_12 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000002346 173.0
TLS2_k127_622700_13 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000938 128.0
TLS2_k127_622700_14 Uncharacterized protein domain (DUF2202) - - - 0.000000000000000000000000000006293 129.0
TLS2_k127_622700_15 Chloride channel K03281 - - 0.000000000000000003003 88.0
TLS2_k127_622700_16 spore germination - - - 0.0000000000000004617 90.0
TLS2_k127_622700_17 - - - - 0.000000000192 67.0
TLS2_k127_622700_18 - - - - 0.0005947 49.0
TLS2_k127_622700_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 431.0
TLS2_k127_622700_3 periplasmic lipoprotein involved in iron transport K07224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 382.0
TLS2_k127_622700_4 Chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 374.0
TLS2_k127_622700_5 Histidine kinase K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 369.0
TLS2_k127_622700_6 PFAM Iron permease FTR1 K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 349.0
TLS2_k127_622700_7 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 319.0
TLS2_k127_622700_8 beta-lactamase domain protein K05555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 302.0
TLS2_k127_622700_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002166 303.0
TLS2_k127_6256870_0 SMART Hedgehog intein hint domain protein - - - 0.0 1586.0
TLS2_k127_6256870_1 PFAM Metallophosphoesterase K01090 - 3.1.3.16 0.0 1264.0
TLS2_k127_6256870_10 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 400.0
TLS2_k127_6256870_11 NADH dehydrogenase K12138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 374.0
TLS2_k127_6256870_12 response regulator, receiver K02483,K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 361.0
TLS2_k127_6256870_13 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 366.0
TLS2_k127_6256870_14 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 325.0
TLS2_k127_6256870_15 Ami_3 K01448 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000137 289.0
TLS2_k127_6256870_16 Regulator of polyketide synthase expression K09684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004941 280.0
TLS2_k127_6256870_17 Intracellular protease K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000001534 261.0
TLS2_k127_6256870_18 Predicted nucleotidyltransferase K07074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003894 267.0
TLS2_k127_6256870_19 RNA repair, ligase-Pnkp-associating, region of Hen1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000519 237.0
TLS2_k127_6256870_2 FAD linked oxidases, C-terminal domain - - - 0.0 1200.0
TLS2_k127_6256870_20 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000001124 229.0
TLS2_k127_6256870_21 transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000003519 220.0
TLS2_k127_6256870_22 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000003583 228.0
TLS2_k127_6256870_23 Hydrolase of the alpha beta-hydrolase K07020 - - 0.00000000000000000000000000000000000000000000000000001872 198.0
TLS2_k127_6256870_24 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000000000001443 184.0
TLS2_k127_6256870_25 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000001988 189.0
TLS2_k127_6256870_26 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000000000000000000004774 178.0
TLS2_k127_6256870_27 - - - - 0.000000000000000000000000000000000000000000003252 176.0
TLS2_k127_6256870_28 DoxX family - - - 0.0000000000000000000000000000000000002424 156.0
TLS2_k127_6256870_29 serine threonine protein kinase - - - 0.0000000000000000000000000000000000004117 150.0
TLS2_k127_6256870_3 Histidine kinase K07646 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 2.7.13.3 7.878e-260 828.0
TLS2_k127_6256870_30 CrcB-like protein, Camphor Resistance (CrcB) K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000001273 141.0
TLS2_k127_6256870_31 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00000000000000000000000000000001439 138.0
TLS2_k127_6256870_33 - - - - 0.0000000000000000000000000001139 122.0
TLS2_k127_6256870_34 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000002974 113.0
TLS2_k127_6256870_35 - - - - 0.000000000000000000000176 103.0
TLS2_k127_6256870_36 - - - - 0.0000000000000000002326 95.0
TLS2_k127_6256870_37 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K12137 - - 0.000000000000001662 78.0
TLS2_k127_6256870_38 - - - - 0.0000000009808 67.0
TLS2_k127_6256870_39 - - - - 0.000394 51.0
TLS2_k127_6256870_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 1.051e-198 646.0
TLS2_k127_6256870_5 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 593.0
TLS2_k127_6256870_6 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 531.0
TLS2_k127_6256870_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 478.0
TLS2_k127_6256870_8 hydrolase K18092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 426.0
TLS2_k127_6256870_9 Inositol monophosphatase family K01092,K05602 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 396.0
TLS2_k127_6301853_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 434.0
TLS2_k127_6301853_1 SEC-C motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 391.0
TLS2_k127_6301853_2 phosphatidylinositol metabolic process K13671 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 389.0
TLS2_k127_6301853_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 357.0
TLS2_k127_6301853_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 330.0
TLS2_k127_6301853_5 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001739 261.0
TLS2_k127_6301853_6 Methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000004861 190.0
TLS2_k127_6301853_7 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000007094 189.0
TLS2_k127_6301853_8 Histidine kinase-like ATPase domain - - - 0.000000000000000000000004918 109.0
TLS2_k127_6309928_0 Bacterial extracellular solute-binding protein K10232 - - 7.773e-209 657.0
TLS2_k127_6309928_1 Conserved hypothetical ATP binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 324.0
TLS2_k127_6309928_2 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000000000000000000000004975 218.0
TLS2_k127_6309928_3 AMP-dependent synthetase - - - 0.0000000000000000000000000000000000000000000000000004015 208.0
TLS2_k127_6309928_4 DNA-binding transcription factor activity K16328 - 2.7.1.83 0.00000000000000000000000000000000001273 141.0
TLS2_k127_6311350_0 glycine betaine transport K02002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 388.0
TLS2_k127_6311350_1 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003767 267.0
TLS2_k127_6311350_2 Adenosylcobinamide amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001124 217.0
TLS2_k127_6311350_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000008534 201.0
TLS2_k127_6311350_4 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000004369 184.0
TLS2_k127_6311350_6 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000001278 139.0
TLS2_k127_6317281_0 von Willebrand factor type A - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.181e-280 883.0
TLS2_k127_6317281_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01697 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 4.2.1.22 9.85e-247 769.0
TLS2_k127_6317281_10 Cro/C1-type HTH DNA-binding domain K07727 - - 0.000000000000000000000000000002257 123.0
TLS2_k127_6317281_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000003632 90.0
TLS2_k127_6317281_13 - - - - 0.00002687 54.0
TLS2_k127_6317281_2 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 9.243e-233 729.0
TLS2_k127_6317281_3 Belongs to the thiolase family K00626 - 2.3.1.9 1.342e-198 626.0
TLS2_k127_6317281_4 G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 370.0
TLS2_k127_6317281_5 cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 325.0
TLS2_k127_6317281_6 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002328 275.0
TLS2_k127_6317281_7 amidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003131 233.0
TLS2_k127_6317281_8 protein conserved in bacteria containing thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000004094 208.0
TLS2_k127_6317281_9 PFAM Antibiotic biosynthesis monooxygenase K21481 - 1.14.99.57 0.00000000000000000000000000000000000000000000007658 173.0
TLS2_k127_63423_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 518.0
TLS2_k127_63423_1 Peptidase S8 and S53 subtilisin kexin sedolisin K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 436.0
TLS2_k127_63423_10 glyoxalase III activity - - - 0.0000000000000000000000001272 107.0
TLS2_k127_63423_11 Histidine phosphatase superfamily (branch 1) K15634 - 5.4.2.12 0.000000000000000000000002359 113.0
TLS2_k127_63423_12 Phage integrase family - - - 0.000000000000000009059 89.0
TLS2_k127_63423_13 Integrase catalytic - - - 0.00000002226 58.0
TLS2_k127_63423_14 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000001709 61.0
TLS2_k127_63423_2 Pyridoxal-dependent decarboxylase conserved domain K01634,K18933 - 4.1.1.11,4.1.1.25,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 386.0
TLS2_k127_63423_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 369.0
TLS2_k127_63423_4 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 322.0
TLS2_k127_63423_5 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 296.0
TLS2_k127_63423_6 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 297.0
TLS2_k127_63423_7 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000006154 230.0
TLS2_k127_63423_8 response to copper ion K07156,K07245,K14166 - - 0.00000000000000000000000000000000000000000000000000000000000000404 242.0
TLS2_k127_63423_9 Domain of unknown function (DUF4142) - - - 0.00000000000000000000000000000000000001494 155.0
TLS2_k127_6346864_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1612.0
TLS2_k127_6346864_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 587.0
TLS2_k127_6346864_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003642 259.0
TLS2_k127_6346864_3 - - - - 0.000000000000000000000000000000000000000000000000000000000001369 214.0
TLS2_k127_6346864_4 Protein of unknown function (DUF3040) - - - 0.0000000000000000000000001064 111.0
TLS2_k127_6346864_5 - - - - 0.000000000000000000001718 101.0
TLS2_k127_638569_0 Condensation domain K15653 - - 0.0 1331.0
TLS2_k127_638569_1 Modulator of DNA gyrase K03568 - - 1.194e-267 833.0
TLS2_k127_638569_10 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 589.0
TLS2_k127_638569_11 Hsp70 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 518.0
TLS2_k127_638569_12 glycine betaine transport K02002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 489.0
TLS2_k127_638569_13 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 424.0
TLS2_k127_638569_14 Aldo/keto reductase family K06221 - 1.1.1.346 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 408.0
TLS2_k127_638569_15 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 396.0
TLS2_k127_638569_16 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 374.0
TLS2_k127_638569_17 Protocatechuate 3,4-dioxygenase beta subunit N terminal K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 353.0
TLS2_k127_638569_18 Taurine catabolism dioxygenase TauD, TfdA family K03119,K06912 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 351.0
TLS2_k127_638569_19 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648,K21788 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 354.0
TLS2_k127_638569_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 6.431e-257 804.0
TLS2_k127_638569_20 Conserved hypothetical ATP binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 321.0
TLS2_k127_638569_21 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 340.0
TLS2_k127_638569_22 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 323.0
TLS2_k127_638569_23 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 340.0
TLS2_k127_638569_24 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 302.0
TLS2_k127_638569_25 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 308.0
TLS2_k127_638569_26 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 306.0
TLS2_k127_638569_27 Roadblock/LC7 domain K07131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002683 254.0
TLS2_k127_638569_28 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000001835 247.0
TLS2_k127_638569_29 Protocatechuate 3,4-dioxygenase alpha subunit K00448 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000001345 231.0
TLS2_k127_638569_3 Nitrate and nitrite sensing - - - 3.014e-226 736.0
TLS2_k127_638569_30 gluconokinase K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000000000000000000000003479 222.0
TLS2_k127_638569_31 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000004298 243.0
TLS2_k127_638569_32 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000007349 202.0
TLS2_k127_638569_33 TIGRFAM deazaflavin-dependent nitroreductase family protein - - - 0.000000000000000000000000000000000000000000000000002836 189.0
TLS2_k127_638569_34 Major facilitator Superfamily K03445 - - 0.00000000000000000000000000000000000000000000000006504 194.0
TLS2_k127_638569_35 - - - - 0.00000000000000000000000000000000000000000000001991 187.0
TLS2_k127_638569_36 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000002616 173.0
TLS2_k127_638569_37 Domain of unknown function (DUF4184) - - - 0.000000000000000000000000000000000000000000004353 178.0
TLS2_k127_638569_38 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000002672 171.0
TLS2_k127_638569_39 FcoT-like thioesterase domain - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0047617,GO:0071704,GO:0071944,GO:0072330,GO:1901576 - 0.000000000000000000000000000000000000008557 153.0
TLS2_k127_638569_4 Putative modulator of DNA gyrase - - - 1.151e-216 691.0
TLS2_k127_638569_40 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000334 155.0
TLS2_k127_638569_41 Protein of unknown function (DUF742) - - - 0.000000000000000000000000000000001348 150.0
TLS2_k127_638569_42 Phosphopantetheine attachment site - - - 0.000000000000005944 87.0
TLS2_k127_638569_43 Domain of unknown function (DUF397) - - - 0.00000000001806 72.0
TLS2_k127_638569_45 - - - - 0.0000000002361 70.0
TLS2_k127_638569_47 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0001685 53.0
TLS2_k127_638569_5 GntP family permease K03299 - - 2.083e-207 664.0
TLS2_k127_638569_6 Dynamin family - - - 1.302e-204 646.0
TLS2_k127_638569_7 Histidine kinase - - - 4.539e-203 644.0
TLS2_k127_638569_8 Dynamin family - - - 4.151e-195 632.0
TLS2_k127_638569_9 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 617.0
TLS2_k127_6394059_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1266.0
TLS2_k127_6394059_1 MMPL family K06994 - - 1.337e-212 691.0
TLS2_k127_6394059_10 Putative peptidoglycan binding domain - - - 0.00000000000000008009 87.0
TLS2_k127_6394059_2 MgsA AAA+ ATPase C terminal K07478 - - 1.618e-199 631.0
TLS2_k127_6394059_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 339.0
TLS2_k127_6394059_4 glycosyl - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 332.0
TLS2_k127_6394059_5 Shikimate dehydrogenase substrate binding domain K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001387 274.0
TLS2_k127_6394059_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000005379 183.0
TLS2_k127_6394059_7 Bacterial protein of unknown function (DUF948) - - - 0.000000000000000000000000000000000000000000001014 169.0
TLS2_k127_6394059_8 - - - - 0.000000000000000000000000000003145 121.0
TLS2_k127_6394059_9 acetyltransferase - - - 0.0000000000000000000768 104.0
TLS2_k127_6413908_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.0 1270.0
TLS2_k127_6413908_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 2.187e-256 802.0
TLS2_k127_6413908_10 glutamine amidotransferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000264 197.0
TLS2_k127_6413908_11 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000005141 186.0
TLS2_k127_6413908_12 Protein of unknown function (DUF1349) K09702 - - 0.000000000000000000000000000000000000000003437 162.0
TLS2_k127_6413908_15 Ion transport protein K10716 - - 0.000000000000000003253 95.0
TLS2_k127_6413908_16 - - - - 0.00000000000002644 76.0
TLS2_k127_6413908_2 PFAM glutamine synthetase catalytic region K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 2.386e-243 770.0
TLS2_k127_6413908_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 591.0
TLS2_k127_6413908_4 Methionine aminopeptidase K01265 GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 508.0
TLS2_k127_6413908_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 409.0
TLS2_k127_6413908_6 polyphosphate glucokinase K00845,K00886 - 2.7.1.2,2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 362.0
TLS2_k127_6413908_7 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 342.0
TLS2_k127_6413908_8 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000003129 249.0
TLS2_k127_6413908_9 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000007749 204.0
TLS2_k127_6442923_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain K21023 - 2.7.7.65 3.646e-219 702.0
TLS2_k127_6442923_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 386.0
TLS2_k127_6442923_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 335.0
TLS2_k127_6442923_3 Periplasmic binding protein LacI transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 329.0
TLS2_k127_6442923_4 LmbE family - - - 0.0000000000000000000000000000000000000000000000000000000000003333 214.0
TLS2_k127_6442923_5 PspC domain - - - 0.000000000000000000000000000000000000000004231 174.0
TLS2_k127_6442923_6 distant relative of homeotic protein bithoraxoid K07131 - - 0.000000000000000000000000000000005698 136.0
TLS2_k127_6474231_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 404.0
TLS2_k127_6474231_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 383.0
TLS2_k127_6474231_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 297.0
TLS2_k127_6474231_3 - - - - 0.00000001822 63.0
TLS2_k127_6474231_4 - - - - 0.00000002016 65.0
TLS2_k127_6484816_0 protein some members contain a von Willebrand factor type A vWA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 592.0
TLS2_k127_6484816_1 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 516.0
TLS2_k127_6484816_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 453.0
TLS2_k127_6484816_3 PFAM RDD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001388 286.0
TLS2_k127_6484816_4 - - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005053 293.0
TLS2_k127_6484816_5 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000001531 227.0
TLS2_k127_6484816_6 Domain of unknown function (DUF4129) - - - 0.000000000000000000000000000000000009846 154.0
TLS2_k127_6528147_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 492.0
TLS2_k127_6528147_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 GO:0008150,GO:0040007 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 481.0
TLS2_k127_6528147_2 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 327.0
TLS2_k127_6528147_3 CDP-alcohol phosphatidyltransferase K00995,K08744 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000001301 252.0
TLS2_k127_6528147_4 protein conserved in bacteria - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000003906 245.0
TLS2_k127_6528147_5 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000000000000000003423 230.0
TLS2_k127_6528147_6 conserved protein (small basic protein) - - - 0.000000000000000000000000000000000000000000000004692 182.0
TLS2_k127_6528147_7 DUF218 domain - - - 0.0000000000000000000000000000000000000002785 156.0
TLS2_k127_6528147_8 Tyrosine phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000007013 144.0
TLS2_k127_6528259_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 4.584e-248 769.0
TLS2_k127_6528259_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity - - - 5.971e-227 716.0
TLS2_k127_6528259_2 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 431.0
TLS2_k127_6528259_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 402.0
TLS2_k127_6528259_4 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 357.0
TLS2_k127_6528259_5 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 333.0
TLS2_k127_6528259_6 ComEC Rec2-related protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000006357 228.0
TLS2_k127_6528259_7 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.0000000000000000000000000000000002887 138.0
TLS2_k127_6528259_8 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000002564 115.0
TLS2_k127_6528259_9 - - - - 0.000000000000000000008563 94.0
TLS2_k127_6540489_0 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 1.577e-276 856.0
TLS2_k127_6540489_1 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 353.0
TLS2_k127_6540489_2 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000004296 205.0
TLS2_k127_6544214_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 4.268e-267 842.0
TLS2_k127_6544214_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.088e-230 723.0
TLS2_k127_6544214_2 Major facilitator superfamily K03449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 306.0
TLS2_k127_6544214_3 gntR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001126 241.0
TLS2_k127_6544214_4 membrane - - - 0.000002372 59.0
TLS2_k127_6554290_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1248.0
TLS2_k127_6554290_1 FtsK/SpoIIIE family K03466 GO:0002790,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0020012,GO:0030312,GO:0030682,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0040007,GO:0042783,GO:0042886,GO:0043207,GO:0044110,GO:0044116,GO:0044117,GO:0044315,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136 - 0.0 1110.0
TLS2_k127_6554290_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009231 231.0
TLS2_k127_6554290_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA - - - 0.0000000000000000000000000000000000000000000000000000000000004377 217.0
TLS2_k127_6554290_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000002945 159.0
TLS2_k127_6554290_5 PPE family - - - 0.0000000000001346 79.0
TLS2_k127_6554290_6 PPE family - - - 0.000000004625 67.0
TLS2_k127_6554290_7 - - - - 0.0002859 50.0
TLS2_k127_6566384_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 9.714e-261 848.0
TLS2_k127_6566384_1 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 611.0
TLS2_k127_6566384_10 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 368.0
TLS2_k127_6566384_11 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 335.0
TLS2_k127_6566384_12 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0008150,GO:0040007 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 317.0
TLS2_k127_6566384_13 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 299.0
TLS2_k127_6566384_14 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002691 275.0
TLS2_k127_6566384_15 Uncharacterized ACR, COG1399 K07040 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002375 258.0
TLS2_k127_6566384_16 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000003845 210.0
TLS2_k127_6566384_17 methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000004187 209.0
TLS2_k127_6566384_18 AsnC family - - - 0.0000000000000000000000000000003384 125.0
TLS2_k127_6566384_19 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000003315 124.0
TLS2_k127_6566384_2 Belongs to the D-alanine--D-alanine ligase family K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 534.0
TLS2_k127_6566384_20 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000000000084 114.0
TLS2_k127_6566384_21 Protein of unknown function (DUF3515) - - - 0.0000000000000000000002753 105.0
TLS2_k127_6566384_3 Dihydroxyacetone kinase K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 540.0
TLS2_k127_6566384_4 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K06148,K16012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 497.0
TLS2_k127_6566384_5 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 458.0
TLS2_k127_6566384_6 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K21173 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 456.0
TLS2_k127_6566384_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 460.0
TLS2_k127_6566384_8 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 445.0
TLS2_k127_6566384_9 cytochrome D ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 387.0
TLS2_k127_656748_0 PFAM chemotaxis sensory transducer K03406 - - 1.912e-265 850.0
TLS2_k127_656748_1 diguanylate cyclase K02488 - 2.7.7.65 4.228e-246 824.0
TLS2_k127_656748_2 PFAM ABC transporter related K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 488.0
TLS2_k127_656748_3 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 445.0
TLS2_k127_656748_4 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 354.0
TLS2_k127_656748_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000124 264.0
TLS2_k127_656748_6 transporter, permease K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000002109 252.0
TLS2_k127_656748_7 Histidine kinase-like ATPases - - - 0.000000000000000004415 101.0
TLS2_k127_656748_8 Chemotaxis signal transduction protein K03408 - - 0.0000000006385 63.0
TLS2_k127_6585676_0 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 624.0
TLS2_k127_6585676_1 protein some members contain a von Willebrand factor type A vWA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 486.0
TLS2_k127_6585676_2 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 467.0
TLS2_k127_6585676_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 439.0
TLS2_k127_6585676_4 penicillin-binding protein K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000339 278.0
TLS2_k127_6585676_5 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001828 259.0
TLS2_k127_6585676_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.00000000000000000003454 100.0
TLS2_k127_663249_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 3.531e-267 831.0
TLS2_k127_663249_1 IMP dehydrogenase K00088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 3.457e-215 670.0
TLS2_k127_663249_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 342.0
TLS2_k127_663249_3 transcriptional regulator K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000001834 252.0
TLS2_k127_663249_4 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.00000000000000000000000000000000000000000000000002198 187.0
TLS2_k127_663249_5 Immunity protein 10 - - - 0.00000000000001845 79.0
TLS2_k127_6636380_0 trehalose synthase K05343 GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576 3.2.1.1,5.4.99.16 1.122e-301 931.0
TLS2_k127_6636380_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 562.0
TLS2_k127_6636380_2 protein, probably involved in trehalose biosynthesis K16146 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.7.1.175 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 485.0
TLS2_k127_6636380_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 310.0
TLS2_k127_6636380_4 His Kinase A (phosphoacceptor) domain K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 308.0
TLS2_k127_6636380_5 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000004422 226.0
TLS2_k127_6636380_6 OmpA family K03286 - - 0.000000000000000000000000000000000000005782 163.0
TLS2_k127_66384_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 2.075e-313 967.0
TLS2_k127_66384_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 488.0
TLS2_k127_66384_2 FIST C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 457.0
TLS2_k127_66384_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 357.0
TLS2_k127_66384_5 TadE-like protein - - - 0.00000007123 61.0
TLS2_k127_66384_6 PFAM GCN5-related N-acetyltransferase - - - 0.0000006868 51.0
TLS2_k127_66384_7 Putative Flp pilus-assembly TadE/G-like - - - 0.0008117 51.0
TLS2_k127_6650015_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.8 0.0 1246.0
TLS2_k127_6650015_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 7.05e-207 656.0
TLS2_k127_6650015_2 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 432.0
TLS2_k127_6650015_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 411.0
TLS2_k127_6650015_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 381.0
TLS2_k127_6650015_5 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000345 248.0
TLS2_k127_6650015_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000000000000002069 217.0
TLS2_k127_6650015_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000008905 157.0
TLS2_k127_6650015_8 protein conserved in bacteria K09764 - - 0.00000000000000000000000000000000003962 139.0
TLS2_k127_6651659_0 Beta-ketoacyl synthase, N-terminal domain - - - 0.0 1508.0
TLS2_k127_6651659_1 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.0 1294.0
TLS2_k127_6656861_0 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 1.845e-255 795.0
TLS2_k127_6656861_1 ABC-type proline glycine betaine transport system permease component K02001 - - 8.025e-235 748.0
TLS2_k127_6656861_2 glycine betaine K02000 - 3.6.3.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 586.0
TLS2_k127_6656861_3 glycine betaine transport K02002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 485.0
TLS2_k127_6656861_4 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 437.0
TLS2_k127_6656861_5 Bacterial transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 306.0
TLS2_k127_665814_0 hydrolase family 62 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 456.0
TLS2_k127_665814_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 443.0
TLS2_k127_665814_2 Domain of unknown function (DUF1963) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003883 239.0
TLS2_k127_665814_3 PFAM glycoside hydrolase, family 10 - - - 0.0000000000000000000000000000000000000000000000000000003785 200.0
TLS2_k127_665814_4 - - - - 0.00000000000000000001244 100.0
TLS2_k127_6683959_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 9.259e-210 661.0
TLS2_k127_6683959_1 Domain of unknown function (DUF4032) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 610.0
TLS2_k127_6683959_10 Cbs domain - - - 0.000000000000000000000000000000000000000000000004194 181.0
TLS2_k127_6683959_11 Globin - - - 0.0000000000000000000000001277 123.0
TLS2_k127_6683959_12 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.0000000000000001539 89.0
TLS2_k127_6683959_2 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 571.0
TLS2_k127_6683959_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 572.0
TLS2_k127_6683959_4 helix_turn _helix lactose operon repressor K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 496.0
TLS2_k127_6683959_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 422.0
TLS2_k127_6683959_6 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 407.0
TLS2_k127_6683959_7 transcriptional regulator K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 302.0
TLS2_k127_6683959_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000003946 239.0
TLS2_k127_6683959_9 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991,K21681 - 1.1.1.405,2.7.7.40,2.7.7.60 0.000000000000000000000000000000000000000000000000000006321 202.0
TLS2_k127_6684886_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.167e-264 818.0
TLS2_k127_6684886_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.433e-255 795.0
TLS2_k127_6684886_10 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 322.0
TLS2_k127_6684886_11 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 303.0
TLS2_k127_6684886_12 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant K07025,K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000000000000000000000000000000000000003232 255.0
TLS2_k127_6684886_13 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001993 226.0
TLS2_k127_6684886_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 7.962e-245 767.0
TLS2_k127_6684886_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 4.791e-232 728.0
TLS2_k127_6684886_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 574.0
TLS2_k127_6684886_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 557.0
TLS2_k127_6684886_6 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 530.0
TLS2_k127_6684886_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 415.0
TLS2_k127_6684886_8 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 378.0
TLS2_k127_6684886_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 339.0
TLS2_k127_6686363_0 Class II Aldolase and Adducin N-terminal domain K01845 - 5.4.3.8 6.869e-256 791.0
TLS2_k127_6686363_1 Belongs to the FGGY kinase family K00854,K00862,K00880 - 2.7.1.17,2.7.1.215,2.7.1.53 3.044e-253 815.0
TLS2_k127_6686363_2 Phosphoribosyltransferase K00768 - 2.4.2.21 6.062e-229 723.0
TLS2_k127_6686363_3 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 383.0
TLS2_k127_670098_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 0.0 1110.0
TLS2_k127_670098_1 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 533.0
TLS2_k127_670098_10 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005557 279.0
TLS2_k127_670098_11 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000001062 206.0
TLS2_k127_670098_12 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000000000000002014 193.0
TLS2_k127_670098_13 sugar transferase - - - 0.00000000000000000000000000000000000000000006043 179.0
TLS2_k127_670098_14 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000005105 163.0
TLS2_k127_670098_15 - - - - 0.000000000000000000000000000000000365 145.0
TLS2_k127_670098_16 chemotaxis K03406 - - 0.0000000000000000000000000000001458 139.0
TLS2_k127_670098_17 - - - - 0.0000000000000000000000000000004577 137.0
TLS2_k127_670098_18 Response regulator receiver - - - 0.000000000000000000000000000000726 125.0
TLS2_k127_670098_19 PFAM lipopolysaccharide biosynthesis protein K08252,K08253 - 2.7.10.1,2.7.10.2 0.0000000000000000000000135 115.0
TLS2_k127_670098_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 450.0
TLS2_k127_670098_20 - - - - 0.000000000000000000004688 102.0
TLS2_k127_670098_21 isomerase K01809 - 5.3.1.8 0.0001636 55.0
TLS2_k127_670098_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 419.0
TLS2_k127_670098_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 406.0
TLS2_k127_670098_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 343.0
TLS2_k127_670098_6 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 321.0
TLS2_k127_670098_7 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 310.0
TLS2_k127_670098_8 Glycoside-hydrolase family GH114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 306.0
TLS2_k127_670098_9 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 311.0
TLS2_k127_6723248_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.919e-312 982.0
TLS2_k127_6723248_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 1.687e-257 809.0
TLS2_k127_6723248_10 CbiX - - - 0.00000000000000000000000000000000000000000000002286 181.0
TLS2_k127_6723248_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000003737 155.0
TLS2_k127_6723248_12 Methyltransferase domain - - - 0.0000000000000000000001053 112.0
TLS2_k127_6723248_13 ThiS family K03636 - - 0.0000000000000000000002352 100.0
TLS2_k127_6723248_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 8.56e-251 788.0
TLS2_k127_6723248_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 608.0
TLS2_k127_6723248_4 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 490.0
TLS2_k127_6723248_5 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 503.0
TLS2_k127_6723248_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 319.0
TLS2_k127_6723248_7 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004311 249.0
TLS2_k127_6723248_8 Belongs to the ILVD EDD family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001371 244.0
TLS2_k127_6723248_9 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000002681 230.0
TLS2_k127_6795115_0 helix_turn_helix, Lux Regulon - - - 1.303e-251 811.0
TLS2_k127_6795115_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 540.0
TLS2_k127_6795115_2 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 445.0
TLS2_k127_6795115_3 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005254 250.0
TLS2_k127_6795115_4 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000005588 147.0
TLS2_k127_6795115_5 - - - - 0.0000000000000000000000000000000002005 153.0
TLS2_k127_6795115_6 - - - - 0.00000000000000000000001069 104.0
TLS2_k127_6795115_7 - - - - 0.000000000000000002654 89.0
TLS2_k127_6819879_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 8.743e-211 662.0
TLS2_k127_6819879_1 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 352.0
TLS2_k127_6819879_10 resistance protein CopC K14166 - - 0.000004382 59.0
TLS2_k127_6819879_11 - - - - 0.0002215 51.0
TLS2_k127_6819879_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 347.0
TLS2_k127_6819879_3 ABC transporter K02049,K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 339.0
TLS2_k127_6819879_4 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000262 272.0
TLS2_k127_6819879_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000002327 263.0
TLS2_k127_6819879_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003108 247.0
TLS2_k127_6819879_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000004069 154.0
TLS2_k127_6819879_8 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000001634 138.0
TLS2_k127_6819879_9 Pfam:DUF385 - - - 0.00000000000000000009591 96.0
TLS2_k127_6828547_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 318.0
TLS2_k127_6828547_1 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006342 286.0
TLS2_k127_6828547_10 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000002666 69.0
TLS2_k127_6828547_2 Virulence activator alpha C-term - - - 0.00000000000000000000000000000000000000000000000000000000471 206.0
TLS2_k127_6828547_3 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000004941 179.0
TLS2_k127_6828547_4 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000005284 175.0
TLS2_k127_6828547_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000009004 158.0
TLS2_k127_6828547_6 Nuclease-related domain - - - 0.0000000000000000000000000000000002165 137.0
TLS2_k127_6828547_7 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000002673 124.0
TLS2_k127_6828547_8 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000002032 118.0
TLS2_k127_6832387_0 PFAM Methane phenol toluene hydroxylase K16242 - - 4.934e-278 863.0
TLS2_k127_6832387_1 Belongs to the aldehyde dehydrogenase family K10217 - 1.2.1.32,1.2.1.85 5.908e-239 750.0
TLS2_k127_6832387_10 MmoB/DmpM family K16244 - - 0.00000000000000000000000000000000004937 135.0
TLS2_k127_6832387_11 Phenol hydroxylase conserved region K16245 - - 0.00000000000000000000000000000001373 129.0
TLS2_k127_6832387_12 - - - - 0.00000000000000000000001499 108.0
TLS2_k127_6832387_13 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000000000002845 97.0
TLS2_k127_6832387_2 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds K01666 - 4.1.3.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 578.0
TLS2_k127_6832387_3 Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds K04073 - 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 498.0
TLS2_k127_6832387_4 PFAM Methane phenol toluene hydroxylase K16243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 409.0
TLS2_k127_6832387_5 hydratase K02554 - 4.2.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 394.0
TLS2_k127_6832387_6 4-oxalocrotonate decarboxylase K01617 - 4.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 388.0
TLS2_k127_6832387_7 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 304.0
TLS2_k127_6832387_8 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 294.0
TLS2_k127_6832387_9 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000274 280.0
TLS2_k127_6856155_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.57e-320 1005.0
TLS2_k127_6856155_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679 - 1.433e-281 874.0
TLS2_k127_6856155_10 ATPase or kinase K06925 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000005998 230.0
TLS2_k127_6856155_11 Glycoprotease family K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000001556 201.0
TLS2_k127_6856155_12 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000005311 193.0
TLS2_k127_6856155_13 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.000000000000000000000000000000000000000000000000001817 192.0
TLS2_k127_6856155_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000007019 173.0
TLS2_k127_6856155_15 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000008213 156.0
TLS2_k127_6856155_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 569.0
TLS2_k127_6856155_3 tRNA (guanine-N2-)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 525.0
TLS2_k127_6856155_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 481.0
TLS2_k127_6856155_5 (Pantothenic acid kinase)) K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 494.0
TLS2_k127_6856155_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 458.0
TLS2_k127_6856155_7 Inosine-uridine preferring nucleoside hydrolase K01239,K01250,K12700 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 415.0
TLS2_k127_6856155_8 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 382.0
TLS2_k127_6856155_9 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 309.0
TLS2_k127_6874884_0 Acetolactate synthase K01652 - 2.2.1.6 8.544e-307 952.0
TLS2_k127_6874884_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 3.744e-204 663.0
TLS2_k127_6874884_2 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 514.0
TLS2_k127_6874884_3 Acetolactate synthase K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006262 274.0
TLS2_k127_6874884_4 - - - - 0.00000000000002697 79.0
TLS2_k127_687679_0 PFAM magnesium chelatase ChlI subunit K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 1.554e-195 632.0
TLS2_k127_687679_1 Aminotransferase K00812,K14267 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.6.1.1,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 524.0
TLS2_k127_687679_10 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000004422 128.0
TLS2_k127_687679_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 473.0
TLS2_k127_687679_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 471.0
TLS2_k127_687679_4 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 364.0
TLS2_k127_687679_5 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 358.0
TLS2_k127_687679_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002142 287.0
TLS2_k127_687679_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001177 273.0
TLS2_k127_687679_8 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000004651 197.0
TLS2_k127_687679_9 peptidase M23B - - - 0.0000000000000000000000000000000000002256 151.0
TLS2_k127_688992_0 MMPL family K06994 - - 2.002e-294 923.0
TLS2_k127_688992_1 MMPL family K06994,K20470 - - 7.449e-217 695.0
TLS2_k127_688992_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000007131 227.0
TLS2_k127_688992_11 SMART helix-turn-helix domain protein - - - 0.00000000000000000001162 96.0
TLS2_k127_688992_12 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000003968 79.0
TLS2_k127_688992_13 Transposase - - - 0.00000000003237 66.0
TLS2_k127_688992_2 Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone K00382 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.8.1.4 9.505e-210 662.0
TLS2_k127_688992_3 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 487.0
TLS2_k127_688992_4 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 415.0
TLS2_k127_688992_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 393.0
TLS2_k127_688992_6 PFAM Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 303.0
TLS2_k127_688992_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001085 302.0
TLS2_k127_688992_8 S-adenosyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005759 286.0
TLS2_k127_688992_9 AIG2-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000004414 226.0
TLS2_k127_689141_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.977e-248 773.0
TLS2_k127_689141_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 5.902e-209 667.0
TLS2_k127_689141_10 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000379 188.0
TLS2_k127_689141_11 SMART helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000000000004265 192.0
TLS2_k127_689141_12 - - - - 0.000000000000000000000000000000000000000964 158.0
TLS2_k127_689141_13 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000001509 136.0
TLS2_k127_689141_14 Bacterial PH domain - - - 0.00000000000000000001729 100.0
TLS2_k127_689141_15 Anti-sigma-K factor rskA - - - 0.000000000000000001557 96.0
TLS2_k127_689141_2 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 598.0
TLS2_k127_689141_3 Belongs to the ABC transporter superfamily K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 512.0
TLS2_k127_689141_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 450.0
TLS2_k127_689141_5 Binding-protein-dependent transport systems inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 382.0
TLS2_k127_689141_6 Aldehyde dehydrogenase K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 387.0
TLS2_k127_689141_7 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 306.0
TLS2_k127_689141_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002686 230.0
TLS2_k127_689141_9 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000003976 224.0
TLS2_k127_6893510_0 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 5.244e-217 693.0
TLS2_k127_6893510_1 phenylacetate-CoA oxygenase K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 555.0
TLS2_k127_6893510_2 Phenylacetate-CoA oxygenase reductase, PaaK subunit K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 495.0
TLS2_k127_6893510_3 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 426.0
TLS2_k127_6893510_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001598 266.0
TLS2_k127_6893510_5 TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit K02612 - - 0.0000000000000000000000000000000000000000000006436 186.0
TLS2_k127_6893510_6 Phenylacetic acid degradation B K02610 - - 0.00000000000000000000000000000000000000000001962 181.0
TLS2_k127_6896687_0 hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 597.0
TLS2_k127_6896687_1 ABC transporter, ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 601.0
TLS2_k127_6896687_10 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000004074 204.0
TLS2_k127_6896687_11 - - - - 0.00000000000000000000001129 102.0
TLS2_k127_6896687_12 - - - - 0.000000000007223 70.0
TLS2_k127_6896687_2 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 496.0
TLS2_k127_6896687_3 Epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 385.0
TLS2_k127_6896687_4 Quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 361.0
TLS2_k127_6896687_5 Belongs to the peptidase S16 family K07177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 365.0
TLS2_k127_6896687_6 UBA ThiF-type NAD FAD binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 350.0
TLS2_k127_6896687_7 UPF0182 protein K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003438 279.0
TLS2_k127_6896687_8 metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002207 261.0
TLS2_k127_6896687_9 - - - - 0.000000000000000000000000000000000000000000000000000000001971 211.0
TLS2_k127_6903398_0 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds K01666 - 4.1.3.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 468.0
TLS2_k127_6903398_1 Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds K04073 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 442.0
TLS2_k127_6903398_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 407.0
TLS2_k127_6903398_3 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 360.0
TLS2_k127_6903398_4 Methyl-accepting chemotaxis K03406,K05874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 337.0
TLS2_k127_6903398_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000153 266.0
TLS2_k127_6903398_6 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003374 251.0
TLS2_k127_6903398_7 protein 4-oxalocrotonate tautomerase homolog - - - 0.0000000000000000000000000000001259 129.0
TLS2_k127_6903398_8 Metal-sensitive transcriptional repressor - - - 0.0000000000000000001363 94.0
TLS2_k127_6924982_0 histone deacetylase K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 582.0
TLS2_k127_6924982_1 Epimerase dehydratase K01784 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 464.0
TLS2_k127_6924982_2 Phosphate acyltransferases - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 456.0
TLS2_k127_6924982_3 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 413.0
TLS2_k127_6924982_4 Cation transport protein K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 388.0
TLS2_k127_6924982_5 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 301.0
TLS2_k127_6924982_6 DNA binding domain, excisionase family - - - 0.0000000000000000000000006736 106.0
TLS2_k127_6924982_7 - - - - 0.000002217 57.0
TLS2_k127_6924982_8 - - - - 0.000002282 55.0
TLS2_k127_6924982_9 - - - - 0.0001334 53.0
TLS2_k127_6951765_0 Sodium:solute symporter family K14393 - - 1.618e-218 707.0
TLS2_k127_6951765_1 Histidine kinase K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 526.0
TLS2_k127_6951765_10 Type ii secretion system K12510 - - 0.0000000000000000006267 100.0
TLS2_k127_6951765_11 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20866 - 3.1.3.10 0.00005438 54.0
TLS2_k127_6951765_2 Type ii secretion system protein e K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 418.0
TLS2_k127_6951765_3 HAD-superfamily subfamily IB hydrolase, TIGR01490 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 377.0
TLS2_k127_6951765_4 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 356.0
TLS2_k127_6951765_5 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000002909 233.0
TLS2_k127_6951765_6 PFAM GPR1 FUN34 yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000004136 209.0
TLS2_k127_6951765_7 protein tyrosine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000001369 214.0
TLS2_k127_6951765_8 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000000000000000000000009647 182.0
TLS2_k127_6951765_9 - - - - 0.000000000000000000000002128 118.0
TLS2_k127_6970880_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1030.0
TLS2_k127_6970880_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 3.689e-271 840.0
TLS2_k127_6970880_10 chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008592 278.0
TLS2_k127_6970880_11 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000005204 246.0
TLS2_k127_6970880_12 belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000000003359 160.0
TLS2_k127_6970880_13 transcriptional regulator K03892 - - 0.0000000000000000000000000000000000002022 145.0
TLS2_k127_6970880_14 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000471 139.0
TLS2_k127_6970880_15 Transglycosylase associated protein - - - 0.000000000000000000000000001077 130.0
TLS2_k127_6970880_16 Putative restriction endonuclease - - - 0.000000000000000000000000002266 120.0
TLS2_k127_6970880_18 - - - - 0.0000001807 55.0
TLS2_k127_6970880_2 Aminotransferase K00812,K08969,K10206,K14261 - 2.6.1.1,2.6.1.83 2.819e-219 685.0
TLS2_k127_6970880_3 PFAM glycosyl transferase family 39 K00728 - 2.4.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 619.0
TLS2_k127_6970880_4 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 441.0
TLS2_k127_6970880_5 domain protein K21688 GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 366.0
TLS2_k127_6970880_6 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 366.0
TLS2_k127_6970880_7 Hydrolase, TatD family K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 365.0
TLS2_k127_6970880_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 353.0
TLS2_k127_6970880_9 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 347.0
TLS2_k127_7023295_0 FAD dependent oxidoreductase central domain - - - 0.0 1177.0
TLS2_k127_7023295_1 Butyryl-CoA dehydrogenase - - - 2.052e-296 919.0
TLS2_k127_7023295_10 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 369.0
TLS2_k127_7023295_11 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 314.0
TLS2_k127_7023295_12 Belongs to the glycosyl hydrolase 32 family K01212,K03332 - 3.2.1.65,3.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 308.0
TLS2_k127_7023295_13 RmlD substrate binding domain K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004165 287.0
TLS2_k127_7023295_14 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005688 280.0
TLS2_k127_7023295_15 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000001433 209.0
TLS2_k127_7023295_16 Protein of unknown function (DUF779) K09959 - - 0.00000000000000000000000000000000000000000000000000000006679 204.0
TLS2_k127_7023295_17 Family of unknown function (DUF5317) - - - 0.000000000000000000000000000000002071 143.0
TLS2_k127_7023295_18 Biotin-lipoyl like K17490 - 2.1.3.1 0.000000000000000000000000000006951 124.0
TLS2_k127_7023295_19 transcriptional regulator - - - 0.00000000000000000000000000009969 124.0
TLS2_k127_7023295_2 Belongs to the aldehyde dehydrogenase family K00138 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016620,GO:0016903,GO:0022607,GO:0033723,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071840 - 5.115e-286 884.0
TLS2_k127_7023295_20 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000006087 113.0
TLS2_k127_7023295_21 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000006373 99.0
TLS2_k127_7023295_22 HesB YadR YfhF-family protein - - - 0.0000000000000001533 84.0
TLS2_k127_7023295_23 - K17489 - 2.1.3.1 0.0000000000004146 77.0
TLS2_k127_7023295_3 Prolyl oligopeptidase family - - - 3.367e-272 856.0
TLS2_k127_7023295_4 Malonate decarboxylase gamma subunit (MdcE) K17489 - 2.1.3.1 5.619e-253 790.0
TLS2_k127_7023295_5 pyruvate K01571,K01960,K03416 - 2.1.3.1,4.1.1.3,6.4.1.1 7.105e-251 782.0
TLS2_k127_7023295_6 Major facilitator Superfamily - - - 1.7e-226 718.0
TLS2_k127_7023295_7 Cytochrome c oxidase K02351,K07245 - - 9.083e-207 667.0
TLS2_k127_7023295_8 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 549.0
TLS2_k127_7023295_9 phytochrome sensor protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 426.0
TLS2_k127_7054803_0 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 569.0
TLS2_k127_7054803_1 Penicillin binding protein transpeptidase domain K05364 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 486.0
TLS2_k127_7054803_10 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000006173 254.0
TLS2_k127_7054803_11 (FHA) domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.000000000000000000000000000000000000000000000000000107 192.0
TLS2_k127_7054803_12 Involved in cell division - - - 0.000000000000000000000000000002291 121.0
TLS2_k127_7054803_13 - - - - 0.000000000000001176 87.0
TLS2_k127_7054803_15 Alpha/beta hydrolase family - - - 0.00001126 49.0
TLS2_k127_7054803_2 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 473.0
TLS2_k127_7054803_3 Phosphatase K20074 GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 431.0
TLS2_k127_7054803_4 Glutamine amidotransferase of anthranilate synthase K01658,K01664 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 354.0
TLS2_k127_7054803_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 363.0
TLS2_k127_7054803_6 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007712 284.0
TLS2_k127_7054803_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007564 271.0
TLS2_k127_7054803_8 (FHA) domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001272 273.0
TLS2_k127_7054803_9 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000008861 247.0
TLS2_k127_7080541_0 Glycosyl Transferase - - - 5.349e-299 935.0
TLS2_k127_7080541_1 PFAM FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 549.0
TLS2_k127_7080541_2 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000000000000000000000000002008 224.0
TLS2_k127_7080541_3 PAS fold K03776 - - 0.000000000000000000000000000000000000000000000000000008425 194.0
TLS2_k127_7080541_4 Two component signalling adaptor domain - - - 0.0000000000000000000000000000000000000000000000483 184.0
TLS2_k127_7080541_5 Rop-like - - - 0.00000000000001895 80.0
TLS2_k127_7080541_6 alginic acid biosynthetic process K01729 - 4.2.2.3 0.000005494 58.0
TLS2_k127_7080541_7 methyl-accepting chemotaxis protein K03406 - - 0.00001708 52.0
TLS2_k127_7080541_8 - - - - 0.0002437 51.0
TLS2_k127_7105013_0 L-lactate permease K03303 - - 3.773e-222 702.0
TLS2_k127_7105013_1 DNA helicase - - - 5.222e-210 678.0
TLS2_k127_7105013_10 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006778 272.0
TLS2_k127_7105013_11 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000837 250.0
TLS2_k127_7105013_12 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000004863 232.0
TLS2_k127_7105013_13 carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000000000000000000000000000000000000000009845 219.0
TLS2_k127_7105013_14 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000005468 203.0
TLS2_k127_7105013_15 Sterol carrier protein - - - 0.00000000000000000000000000000000000009365 162.0
TLS2_k127_7105013_16 - - - - 0.000000002695 68.0
TLS2_k127_7105013_2 LUD domain K18929 - - 4.49e-202 656.0
TLS2_k127_7105013_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 473.0
TLS2_k127_7105013_4 synthase K16167 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006725,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009698,GO:0009699,GO:0009714,GO:0009715,GO:0009987,GO:0016020,GO:0016043,GO:0019438,GO:0019748,GO:0022607,GO:0032991,GO:0034081,GO:0042180,GO:0042181,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 438.0
TLS2_k127_7105013_5 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 434.0
TLS2_k127_7105013_6 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 383.0
TLS2_k127_7105013_7 5-oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 377.0
TLS2_k127_7105013_8 S-adenosyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 354.0
TLS2_k127_7105013_9 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 346.0
TLS2_k127_7105967_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1636.0
TLS2_k127_7105967_1 Type III restriction enzyme, res subunit K03654 - 3.6.4.12 6.571e-311 972.0
TLS2_k127_7105967_10 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 438.0
TLS2_k127_7105967_11 glycosyl transferase group 1 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 455.0
TLS2_k127_7105967_12 Magnesium transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 407.0
TLS2_k127_7105967_13 PAC2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 405.0
TLS2_k127_7105967_14 Dyp-type peroxidase family K15733 - 1.11.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 387.0
TLS2_k127_7105967_15 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 375.0
TLS2_k127_7105967_16 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 355.0
TLS2_k127_7105967_17 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 364.0
TLS2_k127_7105967_19 EamA-like transporter family K11939 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 340.0
TLS2_k127_7105967_2 ATPases associated with a variety of cellular activities - - - 6.931e-250 782.0
TLS2_k127_7105967_20 Transcription regulator MerR, DNA binding K21744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 301.0
TLS2_k127_7105967_21 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 316.0
TLS2_k127_7105967_22 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 293.0
TLS2_k127_7105967_23 thiolester hydrolase activity K07002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003367 271.0
TLS2_k127_7105967_24 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004391 299.0
TLS2_k127_7105967_25 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001821 269.0
TLS2_k127_7105967_26 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007483 258.0
TLS2_k127_7105967_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004616 243.0
TLS2_k127_7105967_28 Bacterial sugar transferase K13012 - - 0.000000000000000000000000000000000000000000000000000000000002076 220.0
TLS2_k127_7105967_29 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000003342 206.0
TLS2_k127_7105967_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00895 - 2.7.1.90 1.197e-219 686.0
TLS2_k127_7105967_30 Crp Fnr family transcriptional regulator K21563 - - 0.0000000000000000000000000000000000000000000000000000005548 201.0
TLS2_k127_7105967_31 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000003597 188.0
TLS2_k127_7105967_32 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000004098 160.0
TLS2_k127_7105967_33 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000138 156.0
TLS2_k127_7105967_34 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000001154 136.0
TLS2_k127_7105967_35 glyoxalase III activity - - - 0.000000000000000000000000000009143 123.0
TLS2_k127_7105967_37 Clp domain protein - - - 0.00000000000000000000000001171 119.0
TLS2_k127_7105967_38 ATPase MipZ - - - 0.00000000000000000000000007617 123.0
TLS2_k127_7105967_39 - - - - 0.00000000000000000000009423 109.0
TLS2_k127_7105967_4 protein conserved in bacteria - - - 1.555e-217 689.0
TLS2_k127_7105967_40 response to copper ion K07156 - - 0.0000000000000000000004796 106.0
TLS2_k127_7105967_41 - - - - 0.00000000000329 78.0
TLS2_k127_7105967_42 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0000001947 65.0
TLS2_k127_7105967_43 PFAM ATP-binding region, ATPase domain protein - - - 0.0002384 53.0
TLS2_k127_7105967_5 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 5.169e-197 629.0
TLS2_k127_7105967_6 Polysaccharide biosynthesis protein CapD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 582.0
TLS2_k127_7105967_7 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 555.0
TLS2_k127_7105967_8 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 510.0
TLS2_k127_7105967_9 DegT/DnrJ/EryC1/StrS aminotransferase family K13010,K19430 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 446.0
TLS2_k127_7110713_0 Belongs to the GPI family K01810 - 5.3.1.9 9.995e-294 914.0
TLS2_k127_7110713_1 Belongs to the RuBisCO large chain family K01601,K08965 - 4.1.1.39,5.3.2.5 6.658e-260 818.0
TLS2_k127_7110713_10 Four helix bundle sensory module for signal transduction K03406 - - 0.000000000000000000000000000000000000007812 149.0
TLS2_k127_7110713_11 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000002422 153.0
TLS2_k127_7110713_12 PFAM Rhodanese domain protein - - - 0.0000000000000000003922 99.0
TLS2_k127_7110713_13 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.0000000000004054 80.0
TLS2_k127_7110713_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.99e-248 797.0
TLS2_k127_7110713_3 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 505.0
TLS2_k127_7110713_4 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 471.0
TLS2_k127_7110713_5 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 399.0
TLS2_k127_7110713_6 Fructose-1-6-bisphosphatase, N-terminal domain K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 350.0
TLS2_k127_7110713_7 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 289.0
TLS2_k127_7110713_8 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001874 287.0
TLS2_k127_7110713_9 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000001829 218.0
TLS2_k127_7120856_0 elongation factor G K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 2.422e-298 931.0
TLS2_k127_7120856_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 554.0
TLS2_k127_7120856_10 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 288.0
TLS2_k127_7120856_11 PFAM histidine triad (HIT) protein K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 283.0
TLS2_k127_7120856_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K00999 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005308 276.0
TLS2_k127_7120856_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001485 273.0
TLS2_k127_7120856_14 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001862 261.0
TLS2_k127_7120856_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005256 252.0
TLS2_k127_7120856_16 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000003713 225.0
TLS2_k127_7120856_17 - - - - 0.00000000000000000000000000000000000000000000001895 179.0
TLS2_k127_7120856_18 nUDIX hydrolase - - - 0.000000000000000000000000000000000000000004134 161.0
TLS2_k127_7120856_19 - - - - 0.000000000000000000000002521 117.0
TLS2_k127_7120856_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 569.0
TLS2_k127_7120856_21 - - - - 0.00000000000000000004433 103.0
TLS2_k127_7120856_22 Preprotein translocase, YajC subunit K03210 - - 0.000000000000000008249 88.0
TLS2_k127_7120856_3 PFAM Glycosyl transferase, group 1 K08256 GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 543.0
TLS2_k127_7120856_4 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 530.0
TLS2_k127_7120856_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 453.0
TLS2_k127_7120856_6 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 441.0
TLS2_k127_7120856_7 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 450.0
TLS2_k127_7120856_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 398.0
TLS2_k127_7120856_9 lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 346.0
TLS2_k127_7131256_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1219.0
TLS2_k127_7131256_1 Malto-oligosyl trehalose synthase K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 5.4.99.15 5.023e-315 986.0
TLS2_k127_7131256_2 acyl-CoA dehydrogenase K09456 - - 5.938e-262 816.0
TLS2_k127_7131256_3 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 378.0
TLS2_k127_7131256_4 Ribonuclease bn K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 348.0
TLS2_k127_7131256_5 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000002708 244.0
TLS2_k127_7149784_0 component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204 1.2.4.1 0.0 1542.0
TLS2_k127_7149784_1 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 1.027e-224 705.0
TLS2_k127_7149784_10 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 364.0
TLS2_k127_7149784_11 polar amino acid ABC transporter, inner membrane subunit K10007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 321.0
TLS2_k127_7149784_12 Belongs to the UPF0246 family K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 292.0
TLS2_k127_7149784_13 Binding-protein-dependent transport system inner membrane component K10006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005782 267.0
TLS2_k127_7149784_14 Zn-ribbon protein, possibly nucleic acid-binding K07164 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002035 260.0
TLS2_k127_7149784_15 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000308 228.0
TLS2_k127_7149784_16 Protein of unknown function (DUF3052) - - - 0.0000000000000000000000000000000000000000000000000000000000000000634 225.0
TLS2_k127_7149784_17 SMART Rhodanese domain protein - - - 0.00000000000000000000000000000000000000000000000000006938 190.0
TLS2_k127_7149784_18 - - - - 0.000000000000000000000000000000000000000000000000005054 194.0
TLS2_k127_7149784_19 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000001372 189.0
TLS2_k127_7149784_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 1.181e-194 649.0
TLS2_k127_7149784_20 - - - - 0.000000000000000000000000000228 126.0
TLS2_k127_7149784_21 - - - - 0.0000000000000000000000000414 113.0
TLS2_k127_7149784_23 - - - - 0.00000001318 65.0
TLS2_k127_7149784_3 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 593.0
TLS2_k127_7149784_4 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 589.0
TLS2_k127_7149784_5 DEAD DEAH box helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 542.0
TLS2_k127_7149784_6 ribonuclease II K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 512.0
TLS2_k127_7149784_7 PFAM ABC transporter related K10008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 390.0
TLS2_k127_7149784_8 Belongs to the bacterial solute-binding protein 3 family K10005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 377.0
TLS2_k127_7149784_9 phosphoglycerate mutase K02226,K22316 - 3.1.26.4,3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 380.0
TLS2_k127_7182217_0 Aminotransferase class-V - - - 6.221e-268 835.0
TLS2_k127_7182217_1 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 339.0
TLS2_k127_7182217_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009639 256.0
TLS2_k127_7182217_3 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000189 172.0
TLS2_k127_7182217_4 - - - - 0.00000000000000000000000000008068 124.0
TLS2_k127_7258889_0 Histidine kinase K07636,K07654 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 496.0
TLS2_k127_7258889_1 Response regulator receiver K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 413.0
TLS2_k127_7258889_2 Lipoprotein lpqB - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 331.0
TLS2_k127_7258889_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000007757 248.0
TLS2_k127_7258889_4 phosphoribosyltransferase - - - 0.00000000000000000000000000000000000009755 154.0
TLS2_k127_7277103_0 Protein of unknown function (DUF3866) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 506.0
TLS2_k127_7277103_1 Transcriptional regulator K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 413.0
TLS2_k127_7277103_2 transcriptional regulator K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 406.0
TLS2_k127_7277103_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001221 281.0
TLS2_k127_7277103_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0008150,GO:0040007 - 0.00000000000000006098 83.0
TLS2_k127_7277103_6 - - - - 0.000004554 52.0
TLS2_k127_7286156_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.575e-251 785.0
TLS2_k127_7286156_1 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 3.105e-239 747.0
TLS2_k127_7286156_2 Exporter of polyketide K01992 - - 3.825e-229 727.0
TLS2_k127_7286156_3 amino acid - - - 9.806e-220 696.0
TLS2_k127_7286156_4 Saccharopine dehydrogenase K00290 - 1.5.1.7 1.135e-208 654.0
TLS2_k127_7286156_5 lactoylglutathione lyase activity - - - 0.000000000000000000001934 104.0
TLS2_k127_7286156_6 - - - - 0.0000000000000000001871 98.0
TLS2_k127_7286156_7 - - - - 0.00008427 56.0
TLS2_k127_7295054_0 (EAL) domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 402.0
TLS2_k127_7295054_1 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 376.0
TLS2_k127_7295054_10 phosphoribosyltransferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000147 121.0
TLS2_k127_7295054_11 methyl-accepting chemotaxis K03406 - - 0.000000000000000000000000002111 127.0
TLS2_k127_7295054_12 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.0000006902 57.0
TLS2_k127_7295054_2 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 361.0
TLS2_k127_7295054_3 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 328.0
TLS2_k127_7295054_4 Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 327.0
TLS2_k127_7295054_5 PFAM chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 312.0
TLS2_k127_7295054_6 Lipase (class 2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009497 243.0
TLS2_k127_7295054_8 Diguanylate cyclase - - - 0.000000000000000000000000000000000146 149.0
TLS2_k127_7295054_9 glycosyl transferase group 1 K00786 - - 0.000000000000000000000000000000001806 143.0
TLS2_k127_7307481_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1107.0
TLS2_k127_7307481_1 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 2.579e-314 975.0
TLS2_k127_7307481_10 DNA ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 538.0
TLS2_k127_7307481_11 Belongs to the FPP GGPP synthase family K00805 - 2.5.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 439.0
TLS2_k127_7307481_12 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 367.0
TLS2_k127_7307481_13 RarD protein K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 366.0
TLS2_k127_7307481_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 362.0
TLS2_k127_7307481_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 338.0
TLS2_k127_7307481_16 NADH dehydrogenase K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 352.0
TLS2_k127_7307481_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K12143 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 327.0
TLS2_k127_7307481_18 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 327.0
TLS2_k127_7307481_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000004969 203.0
TLS2_k127_7307481_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 6.715e-240 749.0
TLS2_k127_7307481_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000001843 146.0
TLS2_k127_7307481_21 Parallel beta-helix repeats - - - 0.000000000000000007895 95.0
TLS2_k127_7307481_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 9.584e-239 744.0
TLS2_k127_7307481_4 FAD binding domain K21401 - 1.3.99.38 9.799e-204 642.0
TLS2_k127_7307481_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 2.533e-200 640.0
TLS2_k127_7307481_6 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 1.415e-197 629.0
TLS2_k127_7307481_7 ATP dependent DNA ligase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 597.0
TLS2_k127_7307481_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 586.0
TLS2_k127_7307481_9 Ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 559.0
TLS2_k127_7308628_0 ABC transporter - - - 1.599e-227 729.0
TLS2_k127_7308628_1 Transmembrane secretion effector K08217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 569.0
TLS2_k127_7308628_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000006537 196.0
TLS2_k127_7308628_3 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000002252 185.0
TLS2_k127_7308628_4 Belongs to the UPF0310 family - - - 0.000000000000000000000000000000000000000000000008695 176.0
TLS2_k127_7308628_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000003903 174.0
TLS2_k127_7308628_6 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000000000000001839 124.0
TLS2_k127_7346109_0 radical SAM domain protein - - - 0.0 1154.0
TLS2_k127_7346109_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 5.43e-322 1000.0
TLS2_k127_7346109_10 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 310.0
TLS2_k127_7346109_11 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 297.0
TLS2_k127_7346109_12 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000002563 220.0
TLS2_k127_7346109_13 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000006464 205.0
TLS2_k127_7346109_14 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000000000000002791 207.0
TLS2_k127_7346109_15 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000003427 164.0
TLS2_k127_7346109_16 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000005602 155.0
TLS2_k127_7346109_17 - - - - 0.000000000000000000000000001008 122.0
TLS2_k127_7346109_19 Protein of unknown function (DUF4233) - - - 0.000000000000000001778 91.0
TLS2_k127_7346109_2 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 2.909e-283 902.0
TLS2_k127_7346109_20 - - - - 0.0006191 46.0
TLS2_k127_7346109_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - 2.308e-229 722.0
TLS2_k127_7346109_4 Folylpolyglutamate synthase K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 596.0
TLS2_k127_7346109_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 597.0
TLS2_k127_7346109_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 534.0
TLS2_k127_7346109_7 Glycosyltransferases involved in cell wall biogenesis K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 474.0
TLS2_k127_7346109_8 PFAM Dyp-type peroxidase K16301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 472.0
TLS2_k127_7346109_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 334.0
TLS2_k127_7367649_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 0.0 1289.0
TLS2_k127_7367649_1 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 615.0
TLS2_k127_7367649_2 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 520.0
TLS2_k127_7367649_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 344.0
TLS2_k127_7367649_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001006 254.0
TLS2_k127_7367649_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000001701 219.0
TLS2_k127_7367649_6 - - - - 0.000000000000001306 84.0
TLS2_k127_7374848_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 2.654e-261 829.0
TLS2_k127_7374848_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.278e-219 703.0
TLS2_k127_7374848_10 S-adenosyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001421 293.0
TLS2_k127_7374848_11 endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004308 269.0
TLS2_k127_7374848_12 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007945 247.0
TLS2_k127_7374848_13 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007424 234.0
TLS2_k127_7374848_14 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000001412 225.0
TLS2_k127_7374848_15 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000008631 211.0
TLS2_k127_7374848_16 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000005553 194.0
TLS2_k127_7374848_17 Protein of unknown function (DUF2089) - - - 0.0000000000000000000000000000000000000000003231 163.0
TLS2_k127_7374848_18 - - - - 0.00000000000000000000000000000000000002793 156.0
TLS2_k127_7374848_19 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000004982 148.0
TLS2_k127_7374848_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 586.0
TLS2_k127_7374848_20 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000001353 134.0
TLS2_k127_7374848_21 Domain of unknown function (DUF397) - - - 0.00000000000000000000000000003024 126.0
TLS2_k127_7374848_22 AMP binding - - - 0.000000000000000000002076 101.0
TLS2_k127_7374848_23 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000003302 98.0
TLS2_k127_7374848_24 Transcriptional regulator - - - 0.000000000000000007134 94.0
TLS2_k127_7374848_26 Cysteine dioxygenase type I - - - 0.0003092 53.0
TLS2_k127_7374848_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 502.0
TLS2_k127_7374848_4 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 494.0
TLS2_k127_7374848_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 453.0
TLS2_k127_7374848_6 abc transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 431.0
TLS2_k127_7374848_7 Helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 396.0
TLS2_k127_7374848_8 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 317.0
TLS2_k127_7374848_9 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 315.0
TLS2_k127_7382652_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1253.0
TLS2_k127_7382652_1 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 413.0
TLS2_k127_7382652_2 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008486 275.0
TLS2_k127_7382652_3 FR47-like protein - - - 0.00000000000000000000000000000000000000000000001239 184.0
TLS2_k127_7395540_0 Alpha beta hydrolase K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 354.0
TLS2_k127_7395540_1 PHP domain K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 321.0
TLS2_k127_7395540_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 316.0
TLS2_k127_7395540_3 N-terminal 7TM region of histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003107 289.0
TLS2_k127_7395540_4 Methyltransferase domain - - - 0.00000001825 67.0
TLS2_k127_7395540_5 - - - - 0.0001561 44.0
TLS2_k127_7401701_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146 - 1.2.1.3,1.2.1.39,1.2.1.8 2.163e-236 740.0
TLS2_k127_7401701_1 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 2.221e-211 666.0
TLS2_k127_7401701_10 PFAM Glycosyl transferase, group 1 K14335 - - 0.0000000000000000000000000000000000000000000000000000000000000000002898 246.0
TLS2_k127_7401701_11 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.000000000000000000000000000000000000000000000000000007328 199.0
TLS2_k127_7401701_12 - - - - 0.0000000000000000001845 94.0
TLS2_k127_7401701_13 transferase activity, transferring acyl groups other than amino-acyl groups K02040,K20276,K21449 - - 0.000000000000004092 81.0
TLS2_k127_7401701_14 polysaccharide biosynthetic process - - - 0.0000000000000317 81.0
TLS2_k127_7401701_15 - - - - 0.0000000000009492 79.0
TLS2_k127_7401701_16 amine dehydrogenase activity - - - 0.0000001188 64.0
TLS2_k127_7401701_17 - - - - 0.000001519 59.0
TLS2_k127_7401701_2 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 596.0
TLS2_k127_7401701_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 443.0
TLS2_k127_7401701_4 Catalyzes the synthesis of activated sulfate K00860,K00958 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 403.0
TLS2_k127_7401701_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 385.0
TLS2_k127_7401701_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 375.0
TLS2_k127_7401701_7 Sortase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 309.0
TLS2_k127_7401701_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 288.0
TLS2_k127_7401701_9 transcriptional regulator K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001158 261.0
TLS2_k127_74151_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 3.328e-316 977.0
TLS2_k127_74151_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.587e-297 925.0
TLS2_k127_74151_10 Clp amino terminal domain, pathogenicity island component - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 325.0
TLS2_k127_74151_11 PFAM CHAD domain containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000001031 210.0
TLS2_k127_74151_12 - - - - 0.00000000000000000000000000000000000000000000000000003598 199.0
TLS2_k127_74151_13 ChaB - - - 0.000000000000000000000000000000000000000000000000008241 188.0
TLS2_k127_74151_14 polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000002283 181.0
TLS2_k127_74151_15 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000001393 164.0
TLS2_k127_74151_16 belongs to the sigma-70 factor family, ECF subfamily - - - 0.000000000000000000000000000000000000000256 157.0
TLS2_k127_74151_17 Protein of unknown function (DUF2795) - - - 0.0000000000000000000001619 104.0
TLS2_k127_74151_18 - - - - 0.0000000000000000002194 102.0
TLS2_k127_74151_2 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 2.701e-287 899.0
TLS2_k127_74151_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 565.0
TLS2_k127_74151_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 514.0
TLS2_k127_74151_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00651 - 2.3.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 478.0
TLS2_k127_74151_6 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 420.0
TLS2_k127_74151_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 376.0
TLS2_k127_74151_8 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 371.0
TLS2_k127_74151_9 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 340.0
TLS2_k127_7429603_0 D-alanine [D-alanyl carrier protein] ligase activity - - - 1.911e-294 937.0
TLS2_k127_7429603_1 ABC transporter transmembrane region K06160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 623.0
TLS2_k127_7429603_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001448 277.0
TLS2_k127_7429603_11 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000000000001494 183.0
TLS2_k127_7429603_12 protein conserved in bacteria K05375 - - 0.000000000000000004096 89.0
TLS2_k127_7429603_13 NADPH-dependent FMN reductase - - - 0.000000000007571 70.0
TLS2_k127_7429603_14 Belongs to the P-Pant transferase superfamily - - - 0.00001004 51.0
TLS2_k127_7429603_2 clavaminate synthase activity K18058 - 1.14.11.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 368.0
TLS2_k127_7429603_3 CHAD domain containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 362.0
TLS2_k127_7429603_4 Low molecular weight phosphotyrosine protein phosphatase K03741,K18701 - 1.20.4.1,2.8.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 341.0
TLS2_k127_7429603_5 Non-ribosomal peptide synthetase modules and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 351.0
TLS2_k127_7429603_6 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 286.0
TLS2_k127_7429603_7 Thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007283 285.0
TLS2_k127_7429603_8 - K14337,K14339 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006458 293.0
TLS2_k127_7429603_9 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006742 266.0
TLS2_k127_760783_0 accessory protein K06959 - - 0.0 1157.0
TLS2_k127_760783_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 1.681e-287 889.0
TLS2_k127_760783_10 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 425.0
TLS2_k127_760783_11 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 377.0
TLS2_k127_760783_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 334.0
TLS2_k127_760783_13 enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003661 284.0
TLS2_k127_760783_14 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002517 279.0
TLS2_k127_760783_15 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001737 271.0
TLS2_k127_760783_16 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000141 252.0
TLS2_k127_760783_17 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000008914 221.0
TLS2_k127_760783_18 Acetyltransferase (GNAT) family K03829 - - 0.0000000000000000000000000000000000000000000000000000000000001916 216.0
TLS2_k127_760783_19 YwiC-like protein - - - 0.00000000000000000000000000000000000000000000000000000001367 212.0
TLS2_k127_760783_2 Carbamoyl-phosphate synthase L chain K01968,K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 4.096e-225 742.0
TLS2_k127_760783_20 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000001423 205.0
TLS2_k127_760783_21 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000005041 200.0
TLS2_k127_760783_22 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000001208 191.0
TLS2_k127_760783_23 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000001274 175.0
TLS2_k127_760783_24 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000005353 158.0
TLS2_k127_760783_25 - - - - 0.0000000000000000000000000000000000001807 155.0
TLS2_k127_760783_26 Transmembrane sensor domain K01768 - 4.6.1.1 0.00000000000000000000000000000005458 143.0
TLS2_k127_760783_28 - - - - 0.000000000000000000000002101 109.0
TLS2_k127_760783_29 RDD family - - - 0.00000000000000000000002785 113.0
TLS2_k127_760783_3 D-alanine [D-alanyl carrier protein] ligase activity - - - 7.813e-223 735.0
TLS2_k127_760783_30 - - - - 0.00000000000003877 74.0
TLS2_k127_760783_31 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000008178 82.0
TLS2_k127_760783_32 - - - - 0.0000000002459 72.0
TLS2_k127_760783_33 - - - - 0.000000146 63.0
TLS2_k127_760783_35 NPCBM/NEW2 domain - - - 0.00005882 53.0
TLS2_k127_760783_4 DNA primase, small subunit K01971 - 6.5.1.1 1.127e-207 659.0
TLS2_k127_760783_5 Protein of unknown function (DUF1156) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 532.0
TLS2_k127_760783_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 485.0
TLS2_k127_760783_7 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 434.0
TLS2_k127_760783_8 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 417.0
TLS2_k127_760783_9 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 428.0
TLS2_k127_77546_0 Trimethylamine methyltransferase (MTTB) - - - 3.083e-272 842.0
TLS2_k127_77546_1 Domain of unknown function (DUF4445) - - - 6.832e-264 833.0
TLS2_k127_77546_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 424.0
TLS2_k127_77546_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 367.0
TLS2_k127_77546_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000833 241.0
TLS2_k127_77546_7 Sigma-70 region 2 - - - 0.0000027 59.0
TLS2_k127_847650_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 5.689e-229 718.0
TLS2_k127_847650_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 507.0
TLS2_k127_847650_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 401.0
TLS2_k127_847650_3 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 405.0
TLS2_k127_847650_4 DNA polymerase LigD polymerase domain K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 385.0
TLS2_k127_847650_5 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 308.0
TLS2_k127_847650_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000009821 74.0
TLS2_k127_847650_7 - - - - 0.0000009396 57.0
TLS2_k127_889655_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 547.0
TLS2_k127_889655_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 356.0
TLS2_k127_889655_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000006485 282.0
TLS2_k127_889655_3 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000004554 190.0
TLS2_k127_889655_4 ATP synthesis coupled electron transport K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000008088 144.0
TLS2_k127_894395_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 465.0
TLS2_k127_894395_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 422.0
TLS2_k127_894395_2 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 391.0
TLS2_k127_894395_3 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 315.0
TLS2_k127_894395_4 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001082 285.0
TLS2_k127_894395_5 LuxR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001454 296.0
TLS2_k127_894395_6 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001785 266.0
TLS2_k127_894395_7 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000007237 190.0
TLS2_k127_894395_8 Amino acid permease - - - 0.000000000000000000000008842 104.0
TLS2_k127_894395_9 Nicotinamide mononucleotide transporter K03811 - - 0.00000000000000004335 82.0
TLS2_k127_928032_0 GTP-binding protein TypA K06207 - - 0.0 1064.0
TLS2_k127_928032_1 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 555.0
TLS2_k127_928032_10 Belongs to the NUDIX hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000006041 182.0
TLS2_k127_928032_11 ParE toxin of type II toxin-antitoxin system, parDE - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000002356 116.0
TLS2_k127_928032_12 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000004289 72.0
TLS2_k127_928032_13 Protein of unknown function (DUF4240) - - - 0.00000003896 63.0
TLS2_k127_928032_14 SnoaL-like domain - - - 0.0000001173 63.0
TLS2_k127_928032_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 504.0
TLS2_k127_928032_3 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 490.0
TLS2_k127_928032_4 extracellular solute-binding protein, family 5 K02035 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 477.0
TLS2_k127_928032_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 401.0
TLS2_k127_928032_6 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 311.0
TLS2_k127_928032_7 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 285.0
TLS2_k127_928032_8 dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000000000000000000000002401 234.0
TLS2_k127_928032_9 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000213 201.0
TLS2_k127_93062_0 type II secretion system protein E K02652 - - 3.567e-245 768.0
TLS2_k127_93062_1 type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 574.0
TLS2_k127_93062_10 carbon utilization - - - 0.0000000000000000004235 93.0
TLS2_k127_93062_11 Prokaryotic N-terminal methylation motif K02650 - - 0.000000002054 65.0
TLS2_k127_93062_12 Hep Hag repeat protein - - - 0.000002846 60.0
TLS2_k127_93062_2 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 569.0
TLS2_k127_93062_3 pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 480.0
TLS2_k127_93062_4 Peptidase A24A, prepilin type IV K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000424 281.0
TLS2_k127_93062_5 Ricin-type beta-trefoil - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001555 291.0
TLS2_k127_93062_6 PFAM Fimbrial assembly family protein - - - 0.00000000000000000000000000006419 133.0
TLS2_k127_93062_7 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000006476 132.0
TLS2_k127_93062_8 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000001501 122.0
TLS2_k127_93062_9 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000004 111.0
TLS2_k127_947318_0 cobaltochelatase CobN subunit K02230 - 6.6.1.2 0.0 1701.0
TLS2_k127_947318_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 1.109e-204 649.0
TLS2_k127_954029_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848,K11942 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0047727,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.4.99.13,5.4.99.2 1.808e-277 857.0
TLS2_k127_954029_1 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 317.0
TLS2_k127_954029_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 318.0
TLS2_k127_954029_3 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 310.0
TLS2_k127_954029_4 PFAM regulatory protein MarR - - - 0.0000000000000000000000000000000000000000000000000000000000000000001107 235.0
TLS2_k127_954029_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000002458 136.0
TLS2_k127_963088_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.348e-288 921.0
TLS2_k127_963088_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 5.443e-208 654.0
TLS2_k127_963088_2 3-5 exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 544.0
TLS2_k127_963088_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 473.0
TLS2_k127_963088_4 luxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 286.0
TLS2_k127_963088_5 Protein of unknown function (DUF3000) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002481 254.0
TLS2_k127_963088_6 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000005714 248.0
TLS2_k127_963088_7 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000000006557 233.0
TLS2_k127_963088_8 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000000000001331 155.0
TLS2_k127_963088_9 aminopeptidase N - - - 0.000000000000000000000000000002414 139.0
TLS2_k127_97672_0 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 402.0
TLS2_k127_97672_1 MerR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 380.0
TLS2_k127_97672_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 386.0
TLS2_k127_97672_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 342.0
TLS2_k127_97672_4 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 294.0
TLS2_k127_97672_5 heme binding - - - 0.00000000000000000000000000000000000000000000002732 184.0
TLS2_k127_97672_6 - - - - 0.000000000000358 78.0
TLS2_k127_97672_7 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000001053 79.0
TLS2_k127_986474_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 4.707e-230 736.0
TLS2_k127_986474_1 Belongs to the TPP enzyme family K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 1.202e-218 692.0
TLS2_k127_986474_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 437.0
TLS2_k127_986474_3 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 359.0
TLS2_k127_986474_4 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000008042 152.0
TLS2_k127_986474_5 Thioesterase - - - 0.000000000000000000000000000007641 127.0
TLS2_k127_993122_0 helicase K10843 - 3.6.4.12 2.641e-301 931.0
TLS2_k127_993122_1 AMP-binding enzyme C-terminal domain K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 3.152e-270 841.0
TLS2_k127_993122_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 339.0
TLS2_k127_993122_11 signal peptide peptidase SppA, 36K type K04773,K04774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 348.0
TLS2_k127_993122_12 Protein of unknown function (DUF3027) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 321.0
TLS2_k127_993122_13 Cold-shock' K03704 - - 0.0000000000000000000000000000000000000000000000000000000000002647 214.0
TLS2_k127_993122_14 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000003321 198.0
TLS2_k127_993122_15 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000001735 176.0
TLS2_k127_993122_16 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000008074 160.0
TLS2_k127_993122_17 trans-aconitate 2-methyltransferase activity K02169 - 2.1.1.197 0.000000000000000000000000000000000000000004267 175.0
TLS2_k127_993122_18 - - - - 0.000000000000000000000000000000000000004247 160.0
TLS2_k127_993122_19 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768,K02798,K11183 - 2.7.1.197,2.7.1.202 0.00000000000000000000000000000000000005326 149.0
TLS2_k127_993122_2 - - - - 8.223e-263 851.0
TLS2_k127_993122_20 PTS system, Lactose/Cellobiose specific IIB subunit K02799 - 2.7.1.197 0.00000000000000000000000000000000006338 141.0
TLS2_k127_993122_21 Divalent ion tolerance protein K03926 - - 0.00000000000000000000000001489 120.0
TLS2_k127_993122_22 HNH nucleases - - - 0.000000009225 57.0
TLS2_k127_993122_23 ATPase activity - - - 0.0002343 53.0
TLS2_k127_993122_3 Helicase conserved C-terminal domain - - - 2.275e-248 796.0
TLS2_k127_993122_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 559.0
TLS2_k127_993122_5 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 524.0
TLS2_k127_993122_6 Phosphotransferase system, EIIC K02798,K02799,K02800 - 2.7.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 500.0
TLS2_k127_993122_7 Major facilitator Superfamily - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 372.0
TLS2_k127_993122_8 DeoR C terminal sensor domain K03436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 351.0
TLS2_k127_993122_9 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 365.0