logo

Overview

ID MAG04028
Name TLS2_bin.70
Sample SMP0104
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Vicinamibacteria
Order Vicinamibacterales
Family 2-12-FULL-66-21
Genus JACCXG01
Species
Assembly information
Completeness (%) 84.52
Contamination (%) 6.25
GC content (%) 69.0
N50 (bp) 17,194
Genome size (bp) 5,257,715

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4238

Gene name Description KEGG GOs EC E-value Score Sequence
TLS2_k127_1000595_0 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000000889 188.0
TLS2_k127_1000595_1 protein kinase activity - - - 0.00000000000259 71.0
TLS2_k127_1000595_2 Exopolysaccharide synthesis, ExoD - - - 0.000002346 54.0
TLS2_k127_1013980_0 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000006553 224.0
TLS2_k127_1013980_1 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000005348 177.0
TLS2_k127_1013980_2 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system - - - 0.0000000000003022 79.0
TLS2_k127_1013980_3 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0000007142 59.0
TLS2_k127_1014190_0 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 532.0
TLS2_k127_1014190_1 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 507.0
TLS2_k127_1014190_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 357.0
TLS2_k127_1014190_11 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 340.0
TLS2_k127_1014190_12 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 302.0
TLS2_k127_1014190_13 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001523 289.0
TLS2_k127_1014190_14 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002324 282.0
TLS2_k127_1014190_15 protein-glutamate methylesterase K00575,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009937 289.0
TLS2_k127_1014190_16 Hypothetical methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005752 250.0
TLS2_k127_1014190_17 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000002094 253.0
TLS2_k127_1014190_18 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000006397 201.0
TLS2_k127_1014190_19 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000000000000000000000000000000001317 195.0
TLS2_k127_1014190_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 471.0
TLS2_k127_1014190_20 protein-glutamate methylesterase K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000003399 205.0
TLS2_k127_1014190_21 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.0000000000000000000000000000000000000000000000004823 187.0
TLS2_k127_1014190_22 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000934 185.0
TLS2_k127_1014190_23 photoreceptor activity - - - 0.00000000000000000000000000000000000000000002151 184.0
TLS2_k127_1014190_24 PFAM ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000002874 166.0
TLS2_k127_1014190_25 protein histidine kinase activity - - - 0.000000000000000000000000000000000001491 148.0
TLS2_k127_1014190_26 - - - - 0.0000000000000000000000000000009614 140.0
TLS2_k127_1014190_27 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000001149 137.0
TLS2_k127_1014190_28 Methyltransferase domain - - - 0.00000000000000000000000000106 126.0
TLS2_k127_1014190_29 PRC-barrel domain - - - 0.00000000000000005735 92.0
TLS2_k127_1014190_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 429.0
TLS2_k127_1014190_30 von Willebrand factor, type A K07114 - - 0.00000000000000008632 94.0
TLS2_k127_1014190_31 - - - - 0.000000000000009541 81.0
TLS2_k127_1014190_33 - - - - 0.00000000002671 77.0
TLS2_k127_1014190_34 copper export protein K07245,K14166 - - 0.00000000004625 73.0
TLS2_k127_1014190_35 CopC domain K07156 - - 0.0000000002936 66.0
TLS2_k127_1014190_4 Belongs to the peptidase C1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 411.0
TLS2_k127_1014190_5 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 425.0
TLS2_k127_1014190_6 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 396.0
TLS2_k127_1014190_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 353.0
TLS2_k127_1014190_8 DNA-binding transcriptional activator of the SARP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 367.0
TLS2_k127_1014190_9 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 355.0
TLS2_k127_1029207_0 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 402.0
TLS2_k127_1029207_1 - - - - 0.0000000000000000000000006239 109.0
TLS2_k127_1029207_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0001282 46.0
TLS2_k127_1033231_0 Dehydrogenase E1 component K11381 - 1.2.4.4 5.351e-276 866.0
TLS2_k127_1033231_1 GTP-binding protein TypA K06207 - - 1.328e-269 844.0
TLS2_k127_1033231_10 5'-3' exonuclease, N-terminal resolvase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 421.0
TLS2_k127_1033231_11 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 420.0
TLS2_k127_1033231_12 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 413.0
TLS2_k127_1033231_13 virulence factor MVIN family protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 378.0
TLS2_k127_1033231_14 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 367.0
TLS2_k127_1033231_15 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 368.0
TLS2_k127_1033231_16 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 366.0
TLS2_k127_1033231_17 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 347.0
TLS2_k127_1033231_18 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 344.0
TLS2_k127_1033231_19 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 294.0
TLS2_k127_1033231_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 571.0
TLS2_k127_1033231_20 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 302.0
TLS2_k127_1033231_21 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001466 269.0
TLS2_k127_1033231_22 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000008867 255.0
TLS2_k127_1033231_23 Protein of unknown function (DUF2400) K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000003258 256.0
TLS2_k127_1033231_24 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000003322 260.0
TLS2_k127_1033231_25 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002997 254.0
TLS2_k127_1033231_26 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000408 245.0
TLS2_k127_1033231_27 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000004434 231.0
TLS2_k127_1033231_28 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000003755 222.0
TLS2_k127_1033231_29 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000009569 198.0
TLS2_k127_1033231_3 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 541.0
TLS2_k127_1033231_30 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000291 205.0
TLS2_k127_1033231_31 to YegS from E. coli K07029 GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 0.000000000000000000000000000000000000000000000000000001445 203.0
TLS2_k127_1033231_32 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000001581 211.0
TLS2_k127_1033231_33 HD domain - - - 0.00000000000000000000000000000000000000000000000000006904 196.0
TLS2_k127_1033231_34 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000001586 186.0
TLS2_k127_1033231_35 glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000005147 184.0
TLS2_k127_1033231_36 YbaK proline--tRNA ligase associated domain protein K19055 - - 0.000000000000000000000000000000000000000000001425 169.0
TLS2_k127_1033231_37 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000007442 176.0
TLS2_k127_1033231_38 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000283 180.0
TLS2_k127_1033231_39 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000002616 165.0
TLS2_k127_1033231_4 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 520.0
TLS2_k127_1033231_40 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000009075 168.0
TLS2_k127_1033231_41 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000000000000000000002136 159.0
TLS2_k127_1033231_42 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000001951 163.0
TLS2_k127_1033231_43 PFAM Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000006556 158.0
TLS2_k127_1033231_44 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000002443 142.0
TLS2_k127_1033231_45 PFAM von Willebrand factor type A K07114,K12511 - - 0.00000000000000000000000000000000321 141.0
TLS2_k127_1033231_46 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000000001034 133.0
TLS2_k127_1033231_47 Yqey-like protein K09117 - - 0.00000000000000000000000000000005299 142.0
TLS2_k127_1033231_48 Cytochrome C assembly protein - - - 0.00000000000000000000000000000006538 136.0
TLS2_k127_1033231_49 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000000001762 136.0
TLS2_k127_1033231_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 494.0
TLS2_k127_1033231_50 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000009271 129.0
TLS2_k127_1033231_51 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000008026 119.0
TLS2_k127_1033231_52 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000001558 128.0
TLS2_k127_1033231_53 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000002254 128.0
TLS2_k127_1033231_54 radical SAM domain protein - - - 0.00000000000000000000000001077 125.0
TLS2_k127_1033231_55 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000225 119.0
TLS2_k127_1033231_56 ATP synthase F(0) sector subunit b K02109 - - 0.000000000000000000000005183 108.0
TLS2_k127_1033231_57 Methionine biosynthesis protein MetW - - - 0.00000000000000001533 93.0
TLS2_k127_1033231_58 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000007663 95.0
TLS2_k127_1033231_59 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000103 93.0
TLS2_k127_1033231_6 membrane protein involved in D-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 484.0
TLS2_k127_1033231_60 PFAM Methyltransferase type 11 - - - 0.00000000000001832 82.0
TLS2_k127_1033231_61 Rhs element vgr protein - - - 0.00000000000003073 83.0
TLS2_k127_1033231_62 Tfp pilus assembly protein FimV - - - 0.0000000000001139 84.0
TLS2_k127_1033231_63 von Willebrand factor, type A K07114 - - 0.0000000000002804 81.0
TLS2_k127_1033231_64 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000003004 76.0
TLS2_k127_1033231_65 PFAM Tetratricopeptide TPR_4 - - - 0.00000000004627 72.0
TLS2_k127_1033231_66 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000005958 73.0
TLS2_k127_1033231_67 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000003662 60.0
TLS2_k127_1033231_68 OprF membrane domain K03286 - - 0.00000003593 63.0
TLS2_k127_1033231_69 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000007689 53.0
TLS2_k127_1033231_7 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 469.0
TLS2_k127_1033231_8 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 458.0
TLS2_k127_1033231_9 COG0534 Na -driven multidrug efflux pump K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 447.0
TLS2_k127_104407_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 415.0
TLS2_k127_104407_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000001225 181.0
TLS2_k127_104407_2 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000003126 170.0
TLS2_k127_104407_3 protein transport - - - 0.0000000000004723 74.0
TLS2_k127_104775_0 Polyketide synthase dehydratase - - - 0.0 1880.0
TLS2_k127_104775_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 1.341e-284 889.0
TLS2_k127_104775_10 Male sterility protein K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 411.0
TLS2_k127_104775_11 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 386.0
TLS2_k127_104775_12 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 327.0
TLS2_k127_104775_13 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 287.0
TLS2_k127_104775_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009747 284.0
TLS2_k127_104775_15 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005041 277.0
TLS2_k127_104775_16 succinate-hydroxymethylglutarate CoA-transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000005946 237.0
TLS2_k127_104775_17 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000988 227.0
TLS2_k127_104775_18 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000006543 222.0
TLS2_k127_104775_19 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000008499 219.0
TLS2_k127_104775_2 PFAM Alcohol dehydrogenase - - - 2.607e-201 642.0
TLS2_k127_104775_20 Inositol monophosphatase family K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000001918 213.0
TLS2_k127_104775_21 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000006304 203.0
TLS2_k127_104775_22 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000002838 158.0
TLS2_k127_104775_23 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000000000000000000009614 98.0
TLS2_k127_104775_24 - - - - 0.0000000000002927 74.0
TLS2_k127_104775_25 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000311 68.0
TLS2_k127_104775_26 Tetratricopeptide repeat - - - 0.00001396 57.0
TLS2_k127_104775_27 Protein of unknown function (DUF2934) - - - 0.0006801 49.0
TLS2_k127_104775_3 Acyl transferase domain K15314 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 550.0
TLS2_k127_104775_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 558.0
TLS2_k127_104775_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 535.0
TLS2_k127_104775_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 518.0
TLS2_k127_104775_7 sulfate adenylyltransferase subunit 2 K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 494.0
TLS2_k127_104775_8 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 496.0
TLS2_k127_104775_9 Acyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 509.0
TLS2_k127_1048851_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 530.0
TLS2_k127_1048851_1 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 479.0
TLS2_k127_1048851_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 421.0
TLS2_k127_1048851_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 330.0
TLS2_k127_1048851_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 298.0
TLS2_k127_1048851_5 DNA modification - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000249 302.0
TLS2_k127_1048851_6 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.000000000000000000000000000000000000000000000000000001465 218.0
TLS2_k127_1048851_7 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000002739 183.0
TLS2_k127_1048851_8 Phosphoglycerate mutase family - - - 0.00000000000000000004616 96.0
TLS2_k127_1053879_0 MacB-like periplasmic core domain - - - 8.582e-271 858.0
TLS2_k127_1053879_1 efflux transmembrane transporter activity - - - 7.655e-264 835.0
TLS2_k127_1053879_10 DoxX - - - 0.000000000000000000000000000000000000000000000000003628 186.0
TLS2_k127_1053879_11 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000004346 195.0
TLS2_k127_1053879_12 transcriptional regulator PadR family - - - 0.0000000000000000000000000000000000000000000000004066 177.0
TLS2_k127_1053879_13 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000006352 189.0
TLS2_k127_1053879_14 PAS fold - - - 0.000000000000000000000000000000000000000000008545 186.0
TLS2_k127_1053879_15 YCII-related domain - - - 0.000000000000000000000000000000000000000002863 160.0
TLS2_k127_1053879_16 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000001933 117.0
TLS2_k127_1053879_17 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000005445 119.0
TLS2_k127_1053879_18 FAD binding domain - - - 0.000000000000000000000006866 106.0
TLS2_k127_1053879_19 domain protein - - - 0.00000000003025 72.0
TLS2_k127_1053879_2 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 625.0
TLS2_k127_1053879_20 domain protein - - - 0.0000000009761 65.0
TLS2_k127_1053879_21 Psort location CytoplasmicMembrane, score - - - 0.000000002547 65.0
TLS2_k127_1053879_3 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 514.0
TLS2_k127_1053879_4 trisaccharide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 503.0
TLS2_k127_1053879_5 Polysaccharide pyruvyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 414.0
TLS2_k127_1053879_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 424.0
TLS2_k127_1053879_7 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 362.0
TLS2_k127_1053879_8 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 297.0
TLS2_k127_1053879_9 metal-dependent membrane protease - - - 0.00000000000000000000000000000000000000000000000000000000000000005511 233.0
TLS2_k127_105952_0 AMP-dependent synthetase - - - 8.55e-291 936.0
TLS2_k127_1077028_0 Na dependent nucleoside K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 407.0
TLS2_k127_1077028_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 366.0
TLS2_k127_1077028_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 307.0
TLS2_k127_1077028_3 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000002595 70.0
TLS2_k127_1077700_0 Sodium:alanine symporter family K03310 - - 9.416e-218 690.0
TLS2_k127_1077700_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000002909 186.0
TLS2_k127_1077700_2 metallopeptidase activity - - - 0.0000000000000000000000000551 121.0
TLS2_k127_1077700_3 Periplasmic or secreted lipoprotein K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.000000000000000000002937 108.0
TLS2_k127_1077700_4 bacterial OsmY and nodulation domain K04065 - - 0.00004318 56.0
TLS2_k127_1082736_0 pyrroloquinoline quinone binding - - - 3.234e-304 960.0
TLS2_k127_1082736_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 573.0
TLS2_k127_1082736_10 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0004775 50.0
TLS2_k127_1082736_2 TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 520.0
TLS2_k127_1082736_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 414.0
TLS2_k127_1082736_4 4-carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 349.0
TLS2_k127_1082736_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006283 282.0
TLS2_k127_1082736_6 Major facilitator superfamily K08191 - - 0.0000000000000000000000000000000000000000000000002373 194.0
TLS2_k127_1082736_7 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.00000000000000000000000000000000000000000000001037 179.0
TLS2_k127_1082736_8 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000001928 74.0
TLS2_k127_1082736_9 polysaccharide deacetylase - - - 0.000001454 61.0
TLS2_k127_1089480_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 524.0
TLS2_k127_1089480_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000001058 217.0
TLS2_k127_1099145_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 1.698e-211 675.0
TLS2_k127_1099145_11 thiolester hydrolase activity K07000 - - 0.0000000000000002341 91.0
TLS2_k127_1099145_12 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000009318 83.0
TLS2_k127_1099145_13 Protein of unknown function (DUF3891) - - - 0.000000001708 69.0
TLS2_k127_1099145_15 DnaB-like helicase C terminal domain K10871 GO:0000003,GO:0000150,GO:0000217,GO:0000280,GO:0000400,GO:0000707,GO:0000724,GO:0000725,GO:0000730,GO:0002831,GO:0002833,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007127,GO:0007131,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016444,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0022414,GO:0022607,GO:0031347,GO:0031349,GO:0032101,GO:0032103,GO:0032991,GO:0033061,GO:0033063,GO:0033554,GO:0034622,GO:0034641,GO:0035825,GO:0042148,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043900,GO:0043902,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0045003,GO:0046483,GO:0048285,GO:0048518,GO:0048583,GO:0048584,GO:0050789,GO:0050896,GO:0051321,GO:0051716,GO:0061982,GO:0065003,GO:0065004,GO:0065007,GO:0071704,GO:0071824,GO:0071840,GO:0080134,GO:0090304,GO:0090735,GO:0097159,GO:0140013,GO:0140097,GO:1900424,GO:1900426,GO:1901360,GO:1901363,GO:1903046 - 0.0002304 51.0
TLS2_k127_1099145_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 379.0
TLS2_k127_1099145_3 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 354.0
TLS2_k127_1099145_4 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000001244 258.0
TLS2_k127_1099145_5 PFAM response regulator receiver K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000006624 234.0
TLS2_k127_1099145_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.00000000000000000000000000000000000000000000000000000001196 216.0
TLS2_k127_1099145_7 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000003164 201.0
TLS2_k127_1099145_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000001061 176.0
TLS2_k127_1099145_9 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000001256 158.0
TLS2_k127_1101186_0 Methionine synthase K00548 - 2.1.1.13 0.0 1115.0
TLS2_k127_1101186_1 Oligopeptidase F K08602 - - 8.533e-201 642.0
TLS2_k127_1101186_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000001593 207.0
TLS2_k127_1101186_11 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000001178 196.0
TLS2_k127_1101186_12 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000002003 181.0
TLS2_k127_1101186_13 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000004344 169.0
TLS2_k127_1101186_14 PFAM phospholipase Carboxylesterase - - - 0.0000000000000000003289 101.0
TLS2_k127_1101186_15 Transporter associated domain - - - 0.000000003511 60.0
TLS2_k127_1101186_16 - - - - 0.0006033 49.0
TLS2_k127_1101186_2 C-terminal region of aryl-sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 588.0
TLS2_k127_1101186_3 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 558.0
TLS2_k127_1101186_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 413.0
TLS2_k127_1101186_5 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000055 288.0
TLS2_k127_1101186_6 Domain of Unknown Function (DUF349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001613 307.0
TLS2_k127_1101186_7 MFS_1 like family K08151,K08153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005209 275.0
TLS2_k127_1101186_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000009943 244.0
TLS2_k127_1101186_9 Beta-lactamase class A K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000001085 234.0
TLS2_k127_1101898_0 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000003303 147.0
TLS2_k127_1101898_1 -O-antigen - - - 0.0000000000000000007959 99.0
TLS2_k127_1101898_2 PEP-CTERM motif - - - 0.000000004314 67.0
TLS2_k127_1101898_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000274 55.0
TLS2_k127_1104382_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 435.0
TLS2_k127_1104382_1 acid dehydrogenase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001335 269.0
TLS2_k127_1104382_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000003373 226.0
TLS2_k127_1104382_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000259 143.0
TLS2_k127_1104382_4 Pfam:Methyltransf_6 - - - 0.00000000000000000005351 94.0
TLS2_k127_1104382_5 - - - - 0.0000000000000004267 82.0
TLS2_k127_1104382_6 succinate dehydrogenase - - - 0.0000000000003603 78.0
TLS2_k127_1104511_0 PFAM Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 370.0
TLS2_k127_1104511_1 OHCU decarboxylase K16840 - 4.1.1.97 0.00000000000000000000000000000000000000000001011 168.0
TLS2_k127_1104511_2 Belongs to the allantoicase family K01477 - 3.5.3.4 0.0000002234 52.0
TLS2_k127_1108632_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1037.0
TLS2_k127_1108632_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.000000000000000000000000000000003016 148.0
TLS2_k127_1108632_2 outer membrane efflux protein K15725 - - 0.00000000000008091 84.0
TLS2_k127_1141896_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 469.0
TLS2_k127_1141896_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 309.0
TLS2_k127_1141896_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001068 295.0
TLS2_k127_1141896_3 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000217 282.0
TLS2_k127_1141896_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001255 265.0
TLS2_k127_1141896_5 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000008074 243.0
TLS2_k127_1141896_6 - K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000004336 245.0
TLS2_k127_1141896_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000008879 219.0
TLS2_k127_1146751_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 3.166e-245 781.0
TLS2_k127_1146751_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 486.0
TLS2_k127_1146751_10 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 321.0
TLS2_k127_1146751_11 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 323.0
TLS2_k127_1146751_12 Oxidoreductase family, C-terminal alpha beta domain K16043 - 1.1.1.370 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 308.0
TLS2_k127_1146751_13 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002803 279.0
TLS2_k127_1146751_14 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000003136 279.0
TLS2_k127_1146751_15 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002237 258.0
TLS2_k127_1146751_16 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000005843 243.0
TLS2_k127_1146751_17 Aldo/keto reductase family K06607 - - 0.00000000000000000000000000000000000000000000000000000000000000000001632 260.0
TLS2_k127_1146751_18 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000005005 164.0
TLS2_k127_1146751_19 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000004488 124.0
TLS2_k127_1146751_2 COGs COG1129 ABC-type sugar transport system ATPase component K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 473.0
TLS2_k127_1146751_21 - - - - 0.00000000000000000000952 99.0
TLS2_k127_1146751_22 - - - - 0.000000000000002018 84.0
TLS2_k127_1146751_23 cAMP biosynthetic process K03641 - - 0.00000000005091 76.0
TLS2_k127_1146751_24 PIN domain K07062 - - 0.0004026 45.0
TLS2_k127_1146751_3 Phage tail sheath protein subtilisin-like domain K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 372.0
TLS2_k127_1146751_4 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 374.0
TLS2_k127_1146751_5 PFAM Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 353.0
TLS2_k127_1146751_6 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 365.0
TLS2_k127_1146751_7 candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238 K18197 - 4.2.2.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 360.0
TLS2_k127_1146751_8 Branched-chain amino acid transport system / permease component K10439,K10440 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 338.0
TLS2_k127_1146751_9 Periplasmic binding proteins and sugar binding domain of LacI family K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 325.0
TLS2_k127_1154059_0 methyltransferase K00590,K07319 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000003782 214.0
TLS2_k127_1154059_1 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000000000000000000000002608 169.0
TLS2_k127_1154059_2 Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000000001227 137.0
TLS2_k127_1159304_0 - - - - 0.0000002242 56.0
TLS2_k127_1168984_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 348.0
TLS2_k127_1168984_1 Glucose inhibited division protein A K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000002515 184.0
TLS2_k127_118163_0 Belongs to the IlvD Edd family K13875 - 4.2.1.25 3.289e-279 867.0
TLS2_k127_118163_1 Fumarylacetoacetate (FAA) hydrolase family K01826 - 5.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 443.0
TLS2_k127_118163_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 316.0
TLS2_k127_118163_3 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000004778 117.0
TLS2_k127_1206709_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1149.0
TLS2_k127_1206709_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 517.0
TLS2_k127_1206709_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 288.0
TLS2_k127_1206709_11 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009136 308.0
TLS2_k127_1206709_12 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001152 285.0
TLS2_k127_1206709_13 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002105 268.0
TLS2_k127_1206709_14 Peptidase family M23 K21472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001883 262.0
TLS2_k127_1206709_15 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000001315 256.0
TLS2_k127_1206709_16 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000001259 237.0
TLS2_k127_1206709_17 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000003189 178.0
TLS2_k127_1206709_18 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000466 183.0
TLS2_k127_1206709_19 Ferredoxin K04755 - - 0.0000000000000000000000000000000000000000000005575 175.0
TLS2_k127_1206709_2 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 470.0
TLS2_k127_1206709_20 ApaG domain K06195 - - 0.000000000000000000000000000000000000000005928 173.0
TLS2_k127_1206709_21 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000009675 149.0
TLS2_k127_1206709_22 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000001595 148.0
TLS2_k127_1206709_23 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000004886 142.0
TLS2_k127_1206709_24 AMMECR1 K09141 - - 0.0000000000000000000000000000000007388 139.0
TLS2_k127_1206709_25 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000002217 119.0
TLS2_k127_1206709_26 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.00000000000000009095 84.0
TLS2_k127_1206709_27 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000009538 85.0
TLS2_k127_1206709_28 - - - - 0.000000003315 59.0
TLS2_k127_1206709_29 metalloendoproteinase 1-like K01402,K07999 - 3.4.24.34 0.00000000519 68.0
TLS2_k127_1206709_3 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 465.0
TLS2_k127_1206709_30 - - - - 0.0000000143 64.0
TLS2_k127_1206709_31 universal stress protein - - - 0.00000005589 60.0
TLS2_k127_1206709_33 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000003649 57.0
TLS2_k127_1206709_34 - - - - 0.00001837 57.0
TLS2_k127_1206709_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 372.0
TLS2_k127_1206709_5 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 346.0
TLS2_k127_1206709_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 327.0
TLS2_k127_1206709_7 PFAM Metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 309.0
TLS2_k127_1206709_8 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 306.0
TLS2_k127_1206709_9 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 306.0
TLS2_k127_124031_0 Associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 380.0
TLS2_k127_124031_1 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 362.0
TLS2_k127_124031_2 Von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001292 275.0
TLS2_k127_124031_3 von Willebrand factor, type A - - - 0.000000000008529 79.0
TLS2_k127_124779_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046872,GO:0071704,GO:1901576 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 442.0
TLS2_k127_124779_1 Sigma-54 interaction domain K06714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003665 252.0
TLS2_k127_124779_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000005071 241.0
TLS2_k127_124779_3 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000001303 160.0
TLS2_k127_124779_4 Protein kinase domain - - - 0.0000004674 62.0
TLS2_k127_124779_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0001414 53.0
TLS2_k127_1262640_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 1.663e-195 632.0
TLS2_k127_1262640_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 2.709e-195 625.0
TLS2_k127_1262640_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 500.0
TLS2_k127_1262640_3 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000008087 227.0
TLS2_k127_1262640_4 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000007739 211.0
TLS2_k127_1262640_5 sequence-specific DNA binding K03719 - - 0.000003196 50.0
TLS2_k127_1264372_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000005278 203.0
TLS2_k127_1264372_1 - - - - 0.000000000000000000001082 103.0
TLS2_k127_1264372_2 Methyltransferase domain - - - 0.00000000000000001797 85.0
TLS2_k127_1264372_3 - - - - 0.00000000006757 65.0
TLS2_k127_1264372_4 - - - - 0.000000001165 71.0
TLS2_k127_1264372_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000713 53.0
TLS2_k127_1264372_7 - - - - 0.0009685 48.0
TLS2_k127_1277232_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1069.0
TLS2_k127_1277232_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 447.0
TLS2_k127_1277232_10 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000009766 178.0
TLS2_k127_1277232_11 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000003394 108.0
TLS2_k127_1277232_12 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000007841 101.0
TLS2_k127_1277232_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 411.0
TLS2_k127_1277232_3 Acts as a magnesium transporter K03281,K04767,K06213,K15986 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 393.0
TLS2_k127_1277232_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 384.0
TLS2_k127_1277232_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 291.0
TLS2_k127_1277232_6 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001211 233.0
TLS2_k127_1277232_7 Transporter associated domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000007892 229.0
TLS2_k127_1277232_8 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000009572 211.0
TLS2_k127_1277232_9 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000754 189.0
TLS2_k127_128404_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 1.556e-293 920.0
TLS2_k127_128404_1 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.00000000000000000000000000000000000000000000002358 178.0
TLS2_k127_1289858_0 Hypothetical glycosyl hydrolase 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 447.0
TLS2_k127_1289858_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000492 286.0
TLS2_k127_1289858_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000001388 196.0
TLS2_k127_1289858_3 PFAM von Willebrand factor type A - - - 0.00000000000000000002383 102.0
TLS2_k127_1305141_0 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 516.0
TLS2_k127_1305141_1 Protein of unknown function (DUF4256) - - - 0.000000000000000000000000000000000000000000000000009866 183.0
TLS2_k127_130971_0 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 428.0
TLS2_k127_130971_1 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000003504 85.0
TLS2_k127_130971_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00002706 57.0
TLS2_k127_1345120_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 606.0
TLS2_k127_1345120_1 Extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000002386 154.0
TLS2_k127_1352541_0 Animal haem peroxidase - - - 1.498e-216 711.0
TLS2_k127_1352541_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 567.0
TLS2_k127_1352541_2 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 480.0
TLS2_k127_1352541_3 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 287.0
TLS2_k127_1358045_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 556.0
TLS2_k127_1358045_1 Oxidoreductase family, C-terminal alpha beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 527.0
TLS2_k127_1358045_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000005997 73.0
TLS2_k127_1366261_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1351.0
TLS2_k127_1366261_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 604.0
TLS2_k127_1366261_10 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000008594 141.0
TLS2_k127_1366261_11 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000002896 80.0
TLS2_k127_1366261_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 572.0
TLS2_k127_1366261_3 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 493.0
TLS2_k127_1366261_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 444.0
TLS2_k127_1366261_5 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 326.0
TLS2_k127_1366261_6 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000007362 247.0
TLS2_k127_1366261_7 gtp cyclohydrolase K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.000000000000000000000000000000000000000000000000000000000287 205.0
TLS2_k127_1366261_8 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000003894 201.0
TLS2_k127_1366261_9 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000000000000003669 165.0
TLS2_k127_1366271_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 6.348e-316 988.0
TLS2_k127_1366271_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.609e-258 828.0
TLS2_k127_1366271_10 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 323.0
TLS2_k127_1366271_11 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 309.0
TLS2_k127_1366271_12 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 291.0
TLS2_k127_1366271_13 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007067 274.0
TLS2_k127_1366271_14 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003669 261.0
TLS2_k127_1366271_15 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000001592 225.0
TLS2_k127_1366271_16 deacetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000001784 216.0
TLS2_k127_1366271_17 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000001669 216.0
TLS2_k127_1366271_18 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000008394 205.0
TLS2_k127_1366271_19 PFAM Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000002422 153.0
TLS2_k127_1366271_2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 1.611e-198 632.0
TLS2_k127_1366271_20 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000001676 143.0
TLS2_k127_1366271_21 RNA methyltransferase K09761 - 2.1.1.193 0.00000000000000000000000000000000006453 144.0
TLS2_k127_1366271_22 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000000000000005204 138.0
TLS2_k127_1366271_23 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000002996 141.0
TLS2_k127_1366271_24 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000002423 125.0
TLS2_k127_1366271_25 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000001874 112.0
TLS2_k127_1366271_26 Ribosomal L32p protein family K02911 - - 0.00000000000000000007511 89.0
TLS2_k127_1366271_27 Lipopolysaccharide-assembly - - - 0.0000000000000000001859 97.0
TLS2_k127_1366271_28 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.000000000002415 73.0
TLS2_k127_1366271_29 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000004014 74.0
TLS2_k127_1366271_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 583.0
TLS2_k127_1366271_30 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000008566 67.0
TLS2_k127_1366271_32 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000004378 57.0
TLS2_k127_1366271_33 Regulatory protein RecX K03565 - - 0.000001122 58.0
TLS2_k127_1366271_4 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 514.0
TLS2_k127_1366271_5 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 499.0
TLS2_k127_1366271_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 418.0
TLS2_k127_1366271_7 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 402.0
TLS2_k127_1366271_8 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 336.0
TLS2_k127_1366271_9 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 329.0
TLS2_k127_1371222_0 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 609.0
TLS2_k127_1371222_1 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 394.0
TLS2_k127_1371222_2 N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001132 209.0
TLS2_k127_1371222_3 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000007923 151.0
TLS2_k127_1380761_0 TonB-dependent receptor - - - 0.0 1455.0
TLS2_k127_1380761_1 Membrane-bound dehydrogenase domain protein - - - 0.0 1085.0
TLS2_k127_1380761_10 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 427.0
TLS2_k127_1380761_11 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 431.0
TLS2_k127_1380761_12 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 403.0
TLS2_k127_1380761_13 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 406.0
TLS2_k127_1380761_14 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 330.0
TLS2_k127_1380761_15 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003163 255.0
TLS2_k127_1380761_16 Domain related to MnhB subunit of Na+/H+ antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000005435 233.0
TLS2_k127_1380761_17 Membrane-bound dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001343 250.0
TLS2_k127_1380761_18 Natural resistance-associated macrophage protein K03322 - - 0.0000000000000000000000000000000000000000000000000000000000004459 226.0
TLS2_k127_1380761_19 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000001588 224.0
TLS2_k127_1380761_2 TonB-dependent receptor - - - 1.252e-283 911.0
TLS2_k127_1380761_20 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000002835 164.0
TLS2_k127_1380761_21 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000000000000000005586 154.0
TLS2_k127_1380761_22 Na+/H+ ion antiporter subunit K05569 - - 0.000000000000000000000000000004999 128.0
TLS2_k127_1380761_23 PFAM Na H antiporter subunit K05571 - - 0.00000000000000000000001419 108.0
TLS2_k127_1380761_24 oxidoreductase, chain 4L K05567 - - 0.0000000000000000000001821 110.0
TLS2_k127_1380761_25 Multiple resistance and pH regulation protein F K05570 - - 0.00000000000000000001689 93.0
TLS2_k127_1380761_26 Histidine kinase - - - 0.0000000000000001867 83.0
TLS2_k127_1380761_27 OsmC-like protein - - - 0.000000000001156 71.0
TLS2_k127_1380761_3 domain protein K03455 - - 2.288e-211 679.0
TLS2_k127_1380761_4 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 9.034e-207 660.0
TLS2_k127_1380761_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 7.861e-206 653.0
TLS2_k127_1380761_6 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 602.0
TLS2_k127_1380761_7 Rhodanese Homology Domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 499.0
TLS2_k127_1380761_8 Sodium/hydrogen exchanger family K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 456.0
TLS2_k127_1380761_9 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 454.0
TLS2_k127_1407544_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1221.0
TLS2_k127_1407544_1 Flavin containing amine oxidoreductase - - - 1.388e-272 845.0
TLS2_k127_1407544_10 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000725 149.0
TLS2_k127_1407544_11 BMC - - - 0.000000000000000000000000000003674 121.0
TLS2_k127_1407544_12 WHG domain - - - 0.000000000000000000006931 102.0
TLS2_k127_1407544_13 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000007847 97.0
TLS2_k127_1407544_14 Putative phosphatase (DUF442) - - - 0.000000000000005965 81.0
TLS2_k127_1407544_15 Periplasmic or secreted lipoprotein - - - 0.0000000000001566 82.0
TLS2_k127_1407544_16 - - - - 0.00005803 55.0
TLS2_k127_1407544_2 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 561.0
TLS2_k127_1407544_3 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 556.0
TLS2_k127_1407544_4 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 435.0
TLS2_k127_1407544_5 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 409.0
TLS2_k127_1407544_6 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 311.0
TLS2_k127_1407544_7 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000002029 243.0
TLS2_k127_1407544_8 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000009559 199.0
TLS2_k127_1407544_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000001803 183.0
TLS2_k127_1421401_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.425e-313 1000.0
TLS2_k127_1421401_1 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.00000000000000000000000000000000000000000000000000000000000000003387 232.0
TLS2_k127_1421401_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000008513 235.0
TLS2_k127_1421401_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000006653 194.0
TLS2_k127_1421401_4 outer membrane efflux protein K03287 - - 0.00000004122 63.0
TLS2_k127_1430420_0 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 315.0
TLS2_k127_1430420_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000001175 201.0
TLS2_k127_1466737_0 PFAM Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 5.558e-198 639.0
TLS2_k127_1466737_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 402.0
TLS2_k127_1466737_2 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 326.0
TLS2_k127_1466737_3 transporter antisigma-factor antagonist STAS K17762 - - 0.0000000000000000000000000000000000001879 142.0
TLS2_k127_1546483_0 PHP domain protein - - - 1.338e-293 923.0
TLS2_k127_1546483_1 PFAM TonB-dependent Receptor Plug - - - 1.345e-284 915.0
TLS2_k127_1546483_2 PFAM TonB-dependent Receptor Plug - - - 2.898e-280 904.0
TLS2_k127_1546483_3 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001019 291.0
TLS2_k127_1546483_4 Domain of unknown function K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000001837 238.0
TLS2_k127_1546483_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0008002 42.0
TLS2_k127_1568548_0 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 304.0
TLS2_k127_1568548_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000029 117.0
TLS2_k127_1579069_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 477.0
TLS2_k127_1579069_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 451.0
TLS2_k127_1579069_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 329.0
TLS2_k127_1579069_3 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000155 240.0
TLS2_k127_1579069_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000023 194.0
TLS2_k127_1579069_5 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000001198 185.0
TLS2_k127_1579069_6 TIGRFAM D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000001385 171.0
TLS2_k127_1579069_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000003568 139.0
TLS2_k127_1579069_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000001381 130.0
TLS2_k127_1582078_0 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001113 275.0
TLS2_k127_1582078_1 PFAM glycosyl transferase family 2 - - - 0.000000000000000001558 87.0
TLS2_k127_1582078_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000002207 87.0
TLS2_k127_1582078_3 DUF218 domain - - - 0.00000000001212 76.0
TLS2_k127_1591988_0 Trehalose utilisation - - - 3.068e-320 1005.0
TLS2_k127_1591988_1 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 6.677e-245 778.0
TLS2_k127_1591988_2 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 565.0
TLS2_k127_1591988_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 312.0
TLS2_k127_1591988_4 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001916 265.0
TLS2_k127_1591988_5 response regulator - - - 0.000000000000000000000000002437 116.0
TLS2_k127_1591988_6 Tetratricopeptide repeat - - - 0.000000000000000000000003983 118.0
TLS2_k127_1591988_7 chitin binding - - - 0.00000000007139 75.0
TLS2_k127_1591988_8 myo-inosose-2 dehydratase activity - - - 0.000000003884 57.0
TLS2_k127_1591988_9 peroxiredoxin activity - - - 0.000008922 53.0
TLS2_k127_1592099_0 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 449.0
TLS2_k127_1592099_1 Phosphoenolpyruvate hydrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 361.0
TLS2_k127_1640872_0 peptidase dimerisation domain protein K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000001799 224.0
TLS2_k127_1640872_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000002266 222.0
TLS2_k127_1640872_2 glyoxalase III activity K02005 - - 0.00000000000000000000000000000000000000000000000000001435 196.0
TLS2_k127_1640872_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000005088 168.0
TLS2_k127_1640872_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000001266 158.0
TLS2_k127_1640872_5 ASCH - - - 0.00000000000000000000000000000000001487 139.0
TLS2_k127_1660271_0 Zinc-binding dehydrogenase - - - 6.92e-293 915.0
TLS2_k127_1660271_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 603.0
TLS2_k127_1660271_10 Hep Hag repeat protein K01179,K01207 - 3.2.1.4,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000207 275.0
TLS2_k127_1660271_11 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001382 251.0
TLS2_k127_1660271_12 protein methyltransferase activity K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000002114 246.0
TLS2_k127_1660271_13 F5/8 type C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000125 246.0
TLS2_k127_1660271_14 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000002357 227.0
TLS2_k127_1660271_15 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000001599 213.0
TLS2_k127_1660271_16 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000101 190.0
TLS2_k127_1660271_17 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000001097 173.0
TLS2_k127_1660271_18 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000002591 160.0
TLS2_k127_1660271_19 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000075 158.0
TLS2_k127_1660271_2 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 585.0
TLS2_k127_1660271_20 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000002299 156.0
TLS2_k127_1660271_21 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000002672 158.0
TLS2_k127_1660271_22 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000276 147.0
TLS2_k127_1660271_23 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000003048 140.0
TLS2_k127_1660271_28 ubiE/COQ5 methyltransferase family - - - 0.000000000004777 76.0
TLS2_k127_1660271_29 Glycosyl transferases group 1 - - - 0.000001086 57.0
TLS2_k127_1660271_3 PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 370.0
TLS2_k127_1660271_30 O-antigen ligase like membrane protein K18814 - - 0.0003914 53.0
TLS2_k127_1660271_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 391.0
TLS2_k127_1660271_5 protein methyltransferase activity K00568,K02687 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 323.0
TLS2_k127_1660271_6 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 325.0
TLS2_k127_1660271_7 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 278.0
TLS2_k127_1660271_8 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002862 278.0
TLS2_k127_1660271_9 Hep Hag repeat protein K01179,K01207 - 3.2.1.4,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000001699 274.0
TLS2_k127_1677243_0 Phosphate acyltransferases K01897 - 6.2.1.3 9.46e-204 653.0
TLS2_k127_1677243_1 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 352.0
TLS2_k127_1677243_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000478 239.0
TLS2_k127_1677243_3 Tetratricopeptide repeat - - - 0.00000000000000000000000001607 121.0
TLS2_k127_1677243_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000004151 94.0
TLS2_k127_1686938_0 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 614.0
TLS2_k127_1686938_1 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 446.0
TLS2_k127_1686938_2 mismatched DNA binding K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 419.0
TLS2_k127_1686938_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000001101 227.0
TLS2_k127_1686938_4 esterase - - - 0.0000001901 54.0
TLS2_k127_17185_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 2.573e-311 971.0
TLS2_k127_1749179_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 6.988e-255 801.0
TLS2_k127_1749179_1 Prolyl oligopeptidase family - - - 2.801e-240 768.0
TLS2_k127_1749179_10 - - - - 0.00000000000000000000000000000002017 128.0
TLS2_k127_1749179_11 cheY-homologous receiver domain - - - 0.000000000000000000000000005609 117.0
TLS2_k127_1749179_12 Lysin motif - - - 0.000000000000000000000009092 108.0
TLS2_k127_1749179_13 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000007788 81.0
TLS2_k127_1749179_14 - - - - 0.000000006186 70.0
TLS2_k127_1749179_15 glycoside hydrolase family 81 - - - 0.00000005606 67.0
TLS2_k127_1749179_2 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 529.0
TLS2_k127_1749179_3 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 404.0
TLS2_k127_1749179_4 L,D-transpeptidase catalytic domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 356.0
TLS2_k127_1749179_5 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 335.0
TLS2_k127_1749179_6 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000001467 258.0
TLS2_k127_1749179_7 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005103 249.0
TLS2_k127_1749179_8 pfam abc K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000005131 244.0
TLS2_k127_1757920_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 461.0
TLS2_k127_1757920_1 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 415.0
TLS2_k127_1757920_10 PFAM Radical SAM domain protein K06871 - - 0.0000000000000000000000000000000000000000000000006498 194.0
TLS2_k127_1757920_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000003766 137.0
TLS2_k127_1757920_12 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000001158 117.0
TLS2_k127_1757920_13 - - - - 0.00000000000000000002081 106.0
TLS2_k127_1757920_14 Bacterial DNA-binding protein K03530 - - 0.0000000000000000006593 89.0
TLS2_k127_1757920_15 Inner membrane component of T3SS, cytoplasmic domain K01990,K21397 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000002927 68.0
TLS2_k127_1757920_16 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000005662 60.0
TLS2_k127_1757920_2 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 395.0
TLS2_k127_1757920_3 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002642 265.0
TLS2_k127_1757920_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005019 247.0
TLS2_k127_1757920_5 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000008861 222.0
TLS2_k127_1757920_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000006145 224.0
TLS2_k127_1757920_7 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000001249 222.0
TLS2_k127_1757920_8 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000001286 193.0
TLS2_k127_1757920_9 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000002951 194.0
TLS2_k127_1769805_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 602.0
TLS2_k127_1769805_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 555.0
TLS2_k127_1769805_10 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001601 292.0
TLS2_k127_1769805_11 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004653 285.0
TLS2_k127_1769805_12 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000363 278.0
TLS2_k127_1769805_13 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000000000000000000002951 245.0
TLS2_k127_1769805_14 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000001444 216.0
TLS2_k127_1769805_15 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000002409 216.0
TLS2_k127_1769805_16 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000008228 205.0
TLS2_k127_1769805_17 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000006056 192.0
TLS2_k127_1769805_18 5-oxoprolinase (ATP-hydrolyzing) activity K01457,K06351,K07160 - 3.5.1.54 0.0000000000000000000000000000000000000000000000001927 199.0
TLS2_k127_1769805_19 Lumazine binding domain K00793,K02858,K14652 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000004232 158.0
TLS2_k127_1769805_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 532.0
TLS2_k127_1769805_20 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000003665 147.0
TLS2_k127_1769805_21 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000008887 140.0
TLS2_k127_1769805_22 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000009026 137.0
TLS2_k127_1769805_23 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000449 119.0
TLS2_k127_1769805_24 - - - - 0.0000000000000000000000003782 116.0
TLS2_k127_1769805_25 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000000001252 110.0
TLS2_k127_1769805_26 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000249 104.0
TLS2_k127_1769805_27 KH domain - - - 0.0000000000004666 72.0
TLS2_k127_1769805_28 - - - - 0.0000000002739 66.0
TLS2_k127_1769805_29 COG0457 FOG TPR repeat - - - 0.0000002564 63.0
TLS2_k127_1769805_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 496.0
TLS2_k127_1769805_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 458.0
TLS2_k127_1769805_5 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 439.0
TLS2_k127_1769805_6 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 332.0
TLS2_k127_1769805_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 315.0
TLS2_k127_1769805_8 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 302.0
TLS2_k127_1769805_9 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 304.0
TLS2_k127_177776_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.218e-255 822.0
TLS2_k127_177776_1 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 588.0
TLS2_k127_177776_10 Histidine kinase K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000005218 216.0
TLS2_k127_177776_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000003604 193.0
TLS2_k127_177776_12 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000001371 198.0
TLS2_k127_177776_13 Methicillin resistance protein - - - 0.0000000000000000000000000000000001436 136.0
TLS2_k127_177776_14 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin K00365 - 1.7.3.3 0.00000000000000000000000003638 121.0
TLS2_k127_177776_15 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000004873 124.0
TLS2_k127_177776_16 Protein of unknown function (DUF2911) - - - 0.00000000000000000000001241 117.0
TLS2_k127_177776_17 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000004013 89.0
TLS2_k127_177776_18 COG1214 Inactive homolog of metal-dependent proteases K01409,K14742 - 2.3.1.234 0.00000000000000001158 93.0
TLS2_k127_177776_19 - - - - 0.0000000003752 66.0
TLS2_k127_177776_2 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 441.0
TLS2_k127_177776_20 - - - - 0.0000000005064 64.0
TLS2_k127_177776_21 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000008451 63.0
TLS2_k127_177776_22 Protein of unknown function (DUF465) K09794 - - 0.0006689 46.0
TLS2_k127_177776_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 394.0
TLS2_k127_177776_4 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 344.0
TLS2_k127_177776_5 PFAM WD40 domain protein beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 339.0
TLS2_k127_177776_6 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 325.0
TLS2_k127_177776_7 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000004938 262.0
TLS2_k127_177776_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000005906 226.0
TLS2_k127_177776_9 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000006843 213.0
TLS2_k127_1807354_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 7.3e-265 836.0
TLS2_k127_1807354_1 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000001278 237.0
TLS2_k127_1807354_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000004687 236.0
TLS2_k127_1807354_3 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000876 204.0
TLS2_k127_1807354_4 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000007839 147.0
TLS2_k127_1807354_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000002291 138.0
TLS2_k127_1807354_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000001133 121.0
TLS2_k127_1807354_7 Required for chromosome condensation and partitioning K03529 - - 0.0000000000002244 70.0
TLS2_k127_1807354_8 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00003354 53.0
TLS2_k127_1810265_0 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 427.0
TLS2_k127_1810265_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10539 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 419.0
TLS2_k127_1810265_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000000000000005594 227.0
TLS2_k127_1810265_3 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000004246 214.0
TLS2_k127_1810265_4 Branched-chain amino acid transport system / permease component K10439,K10440 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000002062 195.0
TLS2_k127_1811829_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 293.0
TLS2_k127_1811829_1 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000443 216.0
TLS2_k127_1811829_2 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000002032 197.0
TLS2_k127_1811829_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000004098 110.0
TLS2_k127_1811829_4 protein tyrosine kinase activity K03593 - - 0.00000000000000000000114 100.0
TLS2_k127_1811829_5 Domain of unknown function (DUF4870) - - - 0.0000000000000000004091 96.0
TLS2_k127_1811829_6 COG3857 ATP-dependent nuclease, subunit B K16899 - 3.6.4.12 0.000000000000001151 93.0
TLS2_k127_1811829_7 - - - - 0.0000003437 59.0
TLS2_k127_1830886_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 584.0
TLS2_k127_1830886_1 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 446.0
TLS2_k127_1830886_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 407.0
TLS2_k127_1830886_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000003187 232.0
TLS2_k127_1830886_4 PAS PAC sensor signal transduction histidine kinase - - - 0.00000000000000000000000006275 125.0
TLS2_k127_1830886_5 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000001604 92.0
TLS2_k127_1830886_6 - - - - 0.0000000002111 68.0
TLS2_k127_1830886_7 - - - - 0.000001185 57.0
TLS2_k127_1873557_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.698e-208 666.0
TLS2_k127_1873557_1 ABC transporter, transmembrane K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 613.0
TLS2_k127_1873557_10 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000001811 259.0
TLS2_k127_1873557_11 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000008359 227.0
TLS2_k127_1873557_12 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000002989 223.0
TLS2_k127_1873557_13 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000002823 213.0
TLS2_k127_1873557_14 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000003884 139.0
TLS2_k127_1873557_15 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000001154 109.0
TLS2_k127_1873557_16 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000002989 100.0
TLS2_k127_1873557_17 Peptidase M23 - - - 0.00000000000000000001201 106.0
TLS2_k127_1873557_18 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000003335 85.0
TLS2_k127_1873557_19 3D domain - - - 0.00000000000002803 81.0
TLS2_k127_1873557_2 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 574.0
TLS2_k127_1873557_20 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000003694 61.0
TLS2_k127_1873557_21 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000161 61.0
TLS2_k127_1873557_22 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0002547 45.0
TLS2_k127_1873557_3 phenylalanyl-tRNA synthetase (beta subunit) K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 427.0
TLS2_k127_1873557_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 379.0
TLS2_k127_1873557_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 373.0
TLS2_k127_1873557_6 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 310.0
TLS2_k127_1873557_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003124 267.0
TLS2_k127_1873557_8 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000004643 258.0
TLS2_k127_1873557_9 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000001712 258.0
TLS2_k127_1875687_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 7.377e-204 655.0
TLS2_k127_1875687_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 302.0
TLS2_k127_1875687_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000001307 158.0
TLS2_k127_1875687_3 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000001774 83.0
TLS2_k127_1876049_0 Selenocysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 442.0
TLS2_k127_1876049_1 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 361.0
TLS2_k127_1876049_2 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003783 286.0
TLS2_k127_1876049_3 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000005257 265.0
TLS2_k127_1876049_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000001081 169.0
TLS2_k127_1876049_5 - - - - 0.00000000000000000000000000000000663 133.0
TLS2_k127_1876049_6 - - - - 0.00000000000003937 80.0
TLS2_k127_1913203_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18334 - 4.2.1.68 1.54e-201 636.0
TLS2_k127_1913203_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 562.0
TLS2_k127_1913203_10 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 323.0
TLS2_k127_1913203_11 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002241 299.0
TLS2_k127_1913203_12 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001084 285.0
TLS2_k127_1913203_13 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000009038 206.0
TLS2_k127_1913203_14 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000002036 193.0
TLS2_k127_1913203_15 transport - - - 0.0000000000000000000000000000000000000000000001369 173.0
TLS2_k127_1913203_16 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000001299 160.0
TLS2_k127_1913203_17 PFAM SAF domain K16849 - 4.2.1.7 0.000000000000000000007812 97.0
TLS2_k127_1913203_18 Bacterial PH domain K08981 - - 0.0000000003366 65.0
TLS2_k127_1913203_2 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 540.0
TLS2_k127_1913203_3 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 545.0
TLS2_k127_1913203_4 TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 421.0
TLS2_k127_1913203_5 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 413.0
TLS2_k127_1913203_6 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 388.0
TLS2_k127_1913203_7 PFAM D-galactarate dehydratase Altronate hydrolase K16846,K16850 - 4.2.1.7,4.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 391.0
TLS2_k127_1913203_8 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 359.0
TLS2_k127_1913203_9 Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 329.0
TLS2_k127_1926181_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.208e-207 651.0
TLS2_k127_1926181_1 Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 454.0
TLS2_k127_1926181_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000001391 235.0
TLS2_k127_1926181_11 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000151 222.0
TLS2_k127_1926181_12 PFAM response regulator receiver K07657 - - 0.0000000000000000000000000000000000000000000000000000000006287 210.0
TLS2_k127_1926181_13 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000002884 117.0
TLS2_k127_1926181_14 Phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000001327 106.0
TLS2_k127_1926181_15 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000006435 64.0
TLS2_k127_1926181_16 PFAM CHAD domain containing protein - - - 0.00000002547 66.0
TLS2_k127_1926181_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 433.0
TLS2_k127_1926181_3 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 396.0
TLS2_k127_1926181_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 359.0
TLS2_k127_1926181_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 328.0
TLS2_k127_1926181_6 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001861 283.0
TLS2_k127_1926181_7 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002159 293.0
TLS2_k127_1926181_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008909 268.0
TLS2_k127_1926181_9 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000008801 244.0
TLS2_k127_1928008_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 593.0
TLS2_k127_1928008_1 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 599.0
TLS2_k127_1928008_10 PHP domain protein - - - 0.000000000000000000000000000008009 138.0
TLS2_k127_1928008_11 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000001496 133.0
TLS2_k127_1928008_12 general secretion pathway protein K02456,K02650 - - 0.0000000000000004527 91.0
TLS2_k127_1928008_13 Type II secretion system protein G K02456 - - 0.00000000000009133 72.0
TLS2_k127_1928008_15 PFAM PKD domain containing protein - - - 0.0001956 53.0
TLS2_k127_1928008_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 424.0
TLS2_k127_1928008_3 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 357.0
TLS2_k127_1928008_4 Permease YjgP YjgQ family protein K07091,K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 366.0
TLS2_k127_1928008_5 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 291.0
TLS2_k127_1928008_6 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 288.0
TLS2_k127_1928008_7 Glucosamine-6-phosphate deaminase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000007915 254.0
TLS2_k127_1928008_8 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001332 254.0
TLS2_k127_1928008_9 BadF/BadG/BcrA/BcrD ATPase family - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000006204 197.0
TLS2_k127_1935077_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 4.537e-259 817.0
TLS2_k127_1935077_1 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 374.0
TLS2_k127_1935077_2 TIGRFAM periplasmic serine protease, Do DeqQ family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 314.0
TLS2_k127_1935077_3 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000002893 273.0
TLS2_k127_1935077_4 CYTH K05873 - 4.6.1.1 0.000000000000000000006908 101.0
TLS2_k127_1935077_6 membrane - - - 0.000000001855 64.0
TLS2_k127_195309_0 TIR domain - - - 0.000000000000000000000000000000000000000302 164.0
TLS2_k127_195309_1 PspC domain protein K03973 - - 0.000000001871 59.0
TLS2_k127_1976907_0 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000001691 269.0
TLS2_k127_1979905_0 efflux transmembrane transporter activity - - - 0.0 1021.0
TLS2_k127_1979905_1 Domain of unknown function (DUF4071) - - - 1.42e-271 855.0
TLS2_k127_1979905_10 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000005264 188.0
TLS2_k127_1979905_11 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000007983 159.0
TLS2_k127_1979905_12 Domain of unknown function (DUF427) - - - 0.0000000000000000000000007677 104.0
TLS2_k127_1979905_13 COG1734 DnaK suppressor protein K06204 - - 0.000000000000001904 81.0
TLS2_k127_1979905_14 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000004823 86.0
TLS2_k127_1979905_15 - - - - 0.00004476 52.0
TLS2_k127_1979905_2 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 1.243e-246 787.0
TLS2_k127_1979905_3 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.976e-244 766.0
TLS2_k127_1979905_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 536.0
TLS2_k127_1979905_5 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 459.0
TLS2_k127_1979905_6 Amidohydrolase family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 371.0
TLS2_k127_1979905_7 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 376.0
TLS2_k127_1979905_8 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009026 248.0
TLS2_k127_1979905_9 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000009445 213.0
TLS2_k127_1989205_0 TrkA-C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 540.0
TLS2_k127_1989205_1 DNA polymerase alpha chain like domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.00000000000000000000000000000000000000000000002256 177.0
TLS2_k127_1999658_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K15408 - 1.10.3.10,1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 535.0
TLS2_k127_1999658_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000001959 191.0
TLS2_k127_2017842_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.555e-207 668.0
TLS2_k127_2017842_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000007298 252.0
TLS2_k127_2017842_2 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000000002054 215.0
TLS2_k127_2017842_3 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000003051 137.0
TLS2_k127_2036607_0 alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 1.839e-265 826.0
TLS2_k127_2036607_1 PBS lyase HEAT-like repeat - - - 6.89e-245 788.0
TLS2_k127_2036607_10 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000007908 166.0
TLS2_k127_2036607_11 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000002153 168.0
TLS2_k127_2036607_12 phosphorelay signal transduction system K03413 - - 0.00000000000000000000000000000000000005213 154.0
TLS2_k127_2036607_13 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000002153 144.0
TLS2_k127_2036607_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 634.0
TLS2_k127_2036607_3 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 567.0
TLS2_k127_2036607_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 448.0
TLS2_k127_2036607_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 442.0
TLS2_k127_2036607_6 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 390.0
TLS2_k127_2036607_7 Methyltransferase, chemotaxis proteins K00575,K13486 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 321.0
TLS2_k127_2036607_8 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000968 284.0
TLS2_k127_2036607_9 CheC inhibitor of MCP methylation K03410 - - 0.00000000000000000000000000000000000000000000000000000000002119 212.0
TLS2_k127_2041936_0 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 8.225e-274 872.0
TLS2_k127_2041936_1 ABC transporter K10441,K10545,K10562 - 3.6.3.17 7.171e-199 636.0
TLS2_k127_2041936_2 IclR helix-turn-helix domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 580.0
TLS2_k127_2041936_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 477.0
TLS2_k127_2041936_4 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 409.0
TLS2_k127_2041936_5 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 364.0
TLS2_k127_2041936_6 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 304.0
TLS2_k127_2041936_7 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 305.0
TLS2_k127_2041936_8 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000003442 169.0
TLS2_k127_2059041_0 binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008929 277.0
TLS2_k127_2059041_1 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10237 - - 0.00000000000000000000000000000000000000005605 154.0
TLS2_k127_2059041_2 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000001966 149.0
TLS2_k127_2062354_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 544.0
TLS2_k127_2069199_0 Iron-containing alcohol dehydrogenase K11173 - 1.1.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 494.0
TLS2_k127_2069199_1 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 347.0
TLS2_k127_2069199_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 342.0
TLS2_k127_2069199_3 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 295.0
TLS2_k127_2069199_4 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
TLS2_k127_2081394_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 2.379e-198 650.0
TLS2_k127_2081394_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 559.0
TLS2_k127_2081394_10 - - - - 0.000000000000000000000000000001344 128.0
TLS2_k127_2081394_11 PFAM von Willebrand factor type A - - - 0.0004578 51.0
TLS2_k127_2081394_2 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 454.0
TLS2_k127_2081394_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 441.0
TLS2_k127_2081394_4 hydrolase activity, acting on ester bonds K07051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 419.0
TLS2_k127_2081394_5 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 310.0
TLS2_k127_2081394_6 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000007417 231.0
TLS2_k127_2081394_7 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000000000000000000000000000000000000000000000000000001335 212.0
TLS2_k127_2081394_8 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000000000000000000000000000000003881 145.0
TLS2_k127_2081394_9 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000001179 146.0
TLS2_k127_2083136_0 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K01281 - 3.4.14.11 1.495e-237 755.0
TLS2_k127_2083136_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.00000000000000000000000000000000000003811 145.0
TLS2_k127_2083136_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.00000000000000004574 95.0
TLS2_k127_2083136_3 - - - - 0.00002855 51.0
TLS2_k127_2084918_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 377.0
TLS2_k127_2084918_1 TIGRFAM FemAB-related protein, PEP-CTERM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 357.0
TLS2_k127_2084918_2 TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 342.0
TLS2_k127_2084918_3 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003053 273.0
TLS2_k127_2084918_4 Sugar transferase, PEP-CTERM EpsH1 system associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001029 262.0
TLS2_k127_2084918_5 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000001269 222.0
TLS2_k127_2084918_6 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000004325 204.0
TLS2_k127_2084918_7 AAA domain K08252 - 2.7.10.1 0.000000000000000000000000000000000003407 149.0
TLS2_k127_2084918_8 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000008593 121.0
TLS2_k127_2084918_9 Glycosyl transferase, family 2 - - - 0.00000000000000001152 93.0
TLS2_k127_2102378_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1050.0
TLS2_k127_2102378_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.827e-282 889.0
TLS2_k127_2102378_10 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004749 288.0
TLS2_k127_2102378_11 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000008463 259.0
TLS2_k127_2102378_12 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001382 258.0
TLS2_k127_2102378_13 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000001274 229.0
TLS2_k127_2102378_14 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000002751 223.0
TLS2_k127_2102378_15 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000001683 212.0
TLS2_k127_2102378_16 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000004501 225.0
TLS2_k127_2102378_17 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000001528 171.0
TLS2_k127_2102378_18 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000001584 158.0
TLS2_k127_2102378_19 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000000002428 160.0
TLS2_k127_2102378_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.073e-248 785.0
TLS2_k127_2102378_20 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000001514 153.0
TLS2_k127_2102378_21 PFAM BioY protein K03523 - - 0.00000000000000000000000000000000000008716 151.0
TLS2_k127_2102378_22 - - - - 0.000000000000000000000000000000000001613 145.0
TLS2_k127_2102378_23 Iron-sulfur cluster insertion protein ErpA K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564 - 0.000000000000000000000000000000000001645 141.0
TLS2_k127_2102378_24 TIGRFAM TonB family K03832 - - 0.00000000000000000000000000000000002642 141.0
TLS2_k127_2102378_25 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.0000000000000000000000000000000006538 138.0
TLS2_k127_2102378_26 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000004355 134.0
TLS2_k127_2102378_27 Belongs to the Fur family K03711 - - 0.000000000000000000000000000137 126.0
TLS2_k127_2102378_28 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000003352 103.0
TLS2_k127_2102378_29 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000003757 104.0
TLS2_k127_2102378_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.823e-227 715.0
TLS2_k127_2102378_30 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000001993 94.0
TLS2_k127_2102378_31 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000001176 92.0
TLS2_k127_2102378_32 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000804 94.0
TLS2_k127_2102378_33 Mo-molybdopterin cofactor metabolic process K03636,K03637,K03752,K21142 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77,2.8.1.12,4.6.1.17 0.000000000000001059 79.0
TLS2_k127_2102378_34 Tetratricopeptide repeat - - - 0.0000225 56.0
TLS2_k127_2102378_4 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 499.0
TLS2_k127_2102378_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 447.0
TLS2_k127_2102378_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 437.0
TLS2_k127_2102378_7 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 368.0
TLS2_k127_2102378_8 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 319.0
TLS2_k127_2102378_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 291.0
TLS2_k127_2112003_0 peptidase activity, acting on L-amino acid peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 493.0
TLS2_k127_2112003_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 367.0
TLS2_k127_2112003_2 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000008855 61.0
TLS2_k127_2117304_0 COG2133 Glucose sorbosone dehydrogenases - - - 4.601e-197 645.0
TLS2_k127_2117304_1 peptidase M13 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 454.0
TLS2_k127_2117304_2 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000003169 191.0
TLS2_k127_2117304_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000005735 162.0
TLS2_k127_2117304_4 efflux transmembrane transporter activity - - - 0.00000000000000000000003237 107.0
TLS2_k127_2117304_5 response regulator receiver K03413 - - 0.000000000000000003335 91.0
TLS2_k127_2117304_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000004148 93.0
TLS2_k127_2117304_7 - - - - 0.00001365 53.0
TLS2_k127_2122255_0 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005381 274.0
TLS2_k127_2122255_1 Tetratricopeptide repeat - - - 0.000000000000000000000000001586 130.0
TLS2_k127_2122255_2 Domain of unknown function (DUF4440) - - - 0.0001255 52.0
TLS2_k127_2126916_0 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000004048 111.0
TLS2_k127_2126916_1 Belongs to the UPF0761 family K07058 - - 0.000000000000000000001373 108.0
TLS2_k127_2138543_0 choline dehydrogenase activity - - - 5.747e-259 808.0
TLS2_k127_2138543_1 Domain of unknown function (DUF4976) - - - 2.35e-240 752.0
TLS2_k127_2138543_10 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 325.0
TLS2_k127_2138543_11 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 309.0
TLS2_k127_2138543_12 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006134 282.0
TLS2_k127_2138543_13 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000136 267.0
TLS2_k127_2138543_14 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001587 258.0
TLS2_k127_2138543_15 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000007152 251.0
TLS2_k127_2138543_16 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001108 209.0
TLS2_k127_2138543_18 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000009225 156.0
TLS2_k127_2138543_19 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.000000000000000000000000000000000000008534 150.0
TLS2_k127_2138543_2 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 607.0
TLS2_k127_2138543_20 - - - - 0.000000000000000000000000000000002488 139.0
TLS2_k127_2138543_21 - - - - 0.00000000000000000000000000236 119.0
TLS2_k127_2138543_22 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000001633 118.0
TLS2_k127_2138543_23 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000006231 90.0
TLS2_k127_2138543_24 Acetyltransferase (GNAT) domain - - - 0.0000000000002655 77.0
TLS2_k127_2138543_25 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000001878 73.0
TLS2_k127_2138543_26 - - - - 0.00002073 48.0
TLS2_k127_2138543_27 COG0457 FOG TPR repeat - - - 0.0002092 54.0
TLS2_k127_2138543_3 gluconolactonase activity K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 550.0
TLS2_k127_2138543_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 506.0
TLS2_k127_2138543_5 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 463.0
TLS2_k127_2138543_6 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 457.0
TLS2_k127_2138543_7 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 373.0
TLS2_k127_2138543_8 Glycosyl transferase family 2 K11936,K14666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 377.0
TLS2_k127_2138543_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 374.0
TLS2_k127_2152763_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 449.0
TLS2_k127_2152763_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 442.0
TLS2_k127_2152763_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 338.0
TLS2_k127_2152763_3 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000001918 157.0
TLS2_k127_2152763_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000007787 126.0
TLS2_k127_2152763_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000294 55.0
TLS2_k127_2157580_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 302.0
TLS2_k127_2157580_1 GlcNAc-PI de-N-acetylase - - - 0.00000008369 57.0
TLS2_k127_2166041_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 627.0
TLS2_k127_2166041_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 503.0
TLS2_k127_2166041_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 460.0
TLS2_k127_2166041_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 361.0
TLS2_k127_2166041_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001878 198.0
TLS2_k127_2166041_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000003023 173.0
TLS2_k127_2166041_6 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000002265 153.0
TLS2_k127_2166041_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000001241 128.0
TLS2_k127_2166041_8 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000001687 121.0
TLS2_k127_2166041_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000002846 117.0
TLS2_k127_2175129_0 PQQ enzyme repeat K00117 - 1.1.5.2 3.568e-287 901.0
TLS2_k127_2175129_1 Membrane-bound dehydrogenase domain - - - 9.338e-271 865.0
TLS2_k127_2175129_10 Spore maturation protein K06373 - - 0.000000000000000000000000000000000000000000000000000000001047 209.0
TLS2_k127_2175129_11 Nucleoside recognition K06374 - - 0.0000000000000000000000000000000000000000000000000000003749 201.0
TLS2_k127_2175129_12 - - - - 0.0000000000000000000000000000000005555 138.0
TLS2_k127_2175129_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000003984 57.0
TLS2_k127_2175129_2 efflux transmembrane transporter activity - - - 1.643e-205 666.0
TLS2_k127_2175129_3 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 520.0
TLS2_k127_2175129_4 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 457.0
TLS2_k127_2175129_5 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 399.0
TLS2_k127_2175129_6 Methane oxygenase PmoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 341.0
TLS2_k127_2175129_7 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001009 275.0
TLS2_k127_2175129_8 RES - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001804 277.0
TLS2_k127_2175129_9 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000001396 221.0
TLS2_k127_2177544_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 468.0
TLS2_k127_2177544_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 308.0
TLS2_k127_2177544_10 - - - - 0.00000002055 63.0
TLS2_k127_2177544_11 - - - - 0.00002718 55.0
TLS2_k127_2177544_12 DNA-sulfur modification-associated - - - 0.0000546 55.0
TLS2_k127_2177544_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001942 285.0
TLS2_k127_2177544_3 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000009273 282.0
TLS2_k127_2177544_4 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000005931 228.0
TLS2_k127_2177544_5 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000008073 175.0
TLS2_k127_2177544_6 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000005131 136.0
TLS2_k127_2177544_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000001087 132.0
TLS2_k127_2177544_8 OsmC-like protein K07397 - - 0.00000000000000007492 88.0
TLS2_k127_2177544_9 - - - - 0.00000000002338 72.0
TLS2_k127_2178685_0 DEAD DEAH box helicase K03724 - - 0.0 1504.0
TLS2_k127_2178685_1 pyrroloquinoline quinone binding - - - 5.436e-284 904.0
TLS2_k127_2178685_10 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 366.0
TLS2_k127_2178685_11 Orotidine 5'-phosphate decarboxylase / HUMPS family K08093 - 4.1.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 307.0
TLS2_k127_2178685_12 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 309.0
TLS2_k127_2178685_13 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008486 284.0
TLS2_k127_2178685_14 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001623 258.0
TLS2_k127_2178685_15 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000003275 240.0
TLS2_k127_2178685_16 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000001433 163.0
TLS2_k127_2178685_17 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.0000000000000000000000000000000000000000622 162.0
TLS2_k127_2178685_18 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000002675 156.0
TLS2_k127_2178685_19 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000002714 151.0
TLS2_k127_2178685_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 571.0
TLS2_k127_2178685_20 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000000001285 111.0
TLS2_k127_2178685_21 - - - - 0.0000003157 54.0
TLS2_k127_2178685_3 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 569.0
TLS2_k127_2178685_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 568.0
TLS2_k127_2178685_5 chorismate binding enzyme K01665,K02619,K03342,K13503,K13950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 497.0
TLS2_k127_2178685_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 445.0
TLS2_k127_2178685_7 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 446.0
TLS2_k127_2178685_8 antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 415.0
TLS2_k127_2178685_9 PFAM FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 357.0
TLS2_k127_2183977_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 6.756e-316 1005.0
TLS2_k127_2183977_1 COG3119 Arylsulfatase A and related enzymes K01135 - 3.1.6.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 542.0
TLS2_k127_2183977_2 COG3119 Arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 509.0
TLS2_k127_2183977_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 520.0
TLS2_k127_2183977_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 377.0
TLS2_k127_2183977_5 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 307.0
TLS2_k127_2183977_6 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 292.0
TLS2_k127_2183977_7 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000386 281.0
TLS2_k127_2183977_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000002526 214.0
TLS2_k127_2183977_9 Protein of unknown function (DUF3303) - - - 0.00000000003169 69.0
TLS2_k127_2186499_0 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 346.0
TLS2_k127_2186499_1 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000005404 127.0
TLS2_k127_2186499_2 PFAM transglutaminase domain protein - - - 0.000005756 55.0
TLS2_k127_2190584_0 negative regulation of protein lipidation K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 395.0
TLS2_k127_2192847_0 ABC transporter transmembrane region K11085 - - 1.136e-249 786.0
TLS2_k127_2192847_1 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000000000000000000000000007817 220.0
TLS2_k127_2192847_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000238 161.0
TLS2_k127_2237386_0 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 0.0000000000000000000004885 106.0
TLS2_k127_2237386_1 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000489 105.0
TLS2_k127_2238013_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 4.39e-276 853.0
TLS2_k127_2238013_1 nitrite transmembrane transporter activity - - - 3.384e-224 711.0
TLS2_k127_2239400_0 nucleotide-excision repair K03701 - - 3.23e-245 774.0
TLS2_k127_2239400_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 522.0
TLS2_k127_2239400_10 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000001298 182.0
TLS2_k127_2239400_11 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000002629 160.0
TLS2_k127_2239400_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000004504 158.0
TLS2_k127_2239400_13 Hsp20/alpha crystallin family K13993 - - 0.00000000000000001203 90.0
TLS2_k127_2239400_15 HEAT repeat - - - 0.00005848 56.0
TLS2_k127_2239400_2 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 387.0
TLS2_k127_2239400_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 300.0
TLS2_k127_2239400_4 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000001876 265.0
TLS2_k127_2239400_5 PFAM Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000007583 229.0
TLS2_k127_2239400_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000001594 224.0
TLS2_k127_2239400_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000009548 213.0
TLS2_k127_2239400_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000003899 218.0
TLS2_k127_2239400_9 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000000000000000009142 186.0
TLS2_k127_2255240_0 COG2041 Sulfite oxidase and related enzymes K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 478.0
TLS2_k127_2255240_1 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00000000000000003668 84.0
TLS2_k127_2266266_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.026e-310 969.0
TLS2_k127_2266266_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 398.0
TLS2_k127_2266266_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002374 282.0
TLS2_k127_2266266_3 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000618 191.0
TLS2_k127_2266266_4 secondary active sulfate transmembrane transporter activity - - - 0.0000000000000005323 81.0
TLS2_k127_2287499_0 AAA ATPase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 494.0
TLS2_k127_2287499_1 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 373.0
TLS2_k127_2287499_10 Patatin-like phospholipase K07001 - - 0.0007883 52.0
TLS2_k127_2287499_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 358.0
TLS2_k127_2287499_3 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007021 293.0
TLS2_k127_2287499_4 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002826 250.0
TLS2_k127_2287499_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000007929 175.0
TLS2_k127_2287499_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000005015 150.0
TLS2_k127_2287499_7 PFAM YeeE YedE family (DUF395) K07112 - - 0.0000000000000000000000000005924 119.0
TLS2_k127_2287499_8 Trypsin K04771,K04772 - 3.4.21.107 0.0001663 53.0
TLS2_k127_2289453_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1071.0
TLS2_k127_2289453_1 Competence protein ComEC K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000001751 253.0
TLS2_k127_2289453_2 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000258 221.0
TLS2_k127_2290011_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000002742 190.0
TLS2_k127_2290011_1 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000007035 169.0
TLS2_k127_2290011_2 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000001341 66.0
TLS2_k127_2320253_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 5.408e-236 747.0
TLS2_k127_2320253_1 cellulose binding - - - 5.837e-217 676.0
TLS2_k127_2320253_10 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001608 295.0
TLS2_k127_2320253_11 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003914 277.0
TLS2_k127_2320253_12 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001563 284.0
TLS2_k127_2320253_13 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000009905 217.0
TLS2_k127_2320253_14 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000002499 213.0
TLS2_k127_2320253_15 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000000002544 157.0
TLS2_k127_2320253_16 Quinoprotein glucose dehydrogenase - - - 0.000000000000000000000000000000000000001391 164.0
TLS2_k127_2320253_17 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000006869 129.0
TLS2_k127_2320253_18 Peptidase family M28 - - - 0.000000000000000000000000007909 128.0
TLS2_k127_2320253_2 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 581.0
TLS2_k127_2320253_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 531.0
TLS2_k127_2320253_4 DNA helicase K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 480.0
TLS2_k127_2320253_5 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 394.0
TLS2_k127_2320253_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 381.0
TLS2_k127_2320253_7 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 344.0
TLS2_k127_2320253_8 Glutamine cyclotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 322.0
TLS2_k127_2320253_9 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 316.0
TLS2_k127_2324143_0 PFAM Blue (type 1) copper domain K09992 - - 0.0 1073.0
TLS2_k127_2324143_1 Glucose / Sorbosone dehydrogenase K08738 - - 0.0 1033.0
TLS2_k127_2324143_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 575.0
TLS2_k127_2324143_3 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 559.0
TLS2_k127_2324143_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 435.0
TLS2_k127_2324143_5 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000297 234.0
TLS2_k127_2332512_0 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 408.0
TLS2_k127_2332512_1 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007177 287.0
TLS2_k127_2332512_10 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.0000001432 56.0
TLS2_k127_2332512_11 PFAM Glycosyl transferase, group 1 - - - 0.00004119 56.0
TLS2_k127_2332512_12 Polysaccharide biosynthesis protein - - - 0.0009404 51.0
TLS2_k127_2332512_2 Belongs to the DegT DnrJ EryC1 family K13010,K20429 - 2.6.1.102,2.6.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000006509 259.0
TLS2_k127_2332512_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000001452 189.0
TLS2_k127_2332512_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000001671 163.0
TLS2_k127_2332512_5 Protein of unknown function DUF115 - - - 0.0000000000000000000000003149 124.0
TLS2_k127_2332512_6 Bacterial transferase hexapeptide (three repeats) K00640 - 2.3.1.30 0.000000000000000000002297 109.0
TLS2_k127_2332512_7 cyclopropane-fatty-acyl-phospholipid synthase - - - 0.000000000000001608 92.0
TLS2_k127_2332512_8 Asparagine synthase K01953 - 6.3.5.4 0.0000000000006031 71.0
TLS2_k127_2332512_9 Methyltransferase domain - - - 0.000000000004779 76.0
TLS2_k127_2338024_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 449.0
TLS2_k127_2338024_1 - - - - 0.000000000000000000000000000000000000000000000000000000006093 205.0
TLS2_k127_2338024_2 methylamine metabolic process K03885,K15977 - 1.6.99.3 0.000000000000000000000000000175 122.0
TLS2_k127_2338024_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000016 103.0
TLS2_k127_2345560_0 regulation of response to stimulus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 393.0
TLS2_k127_2345560_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001806 269.0
TLS2_k127_2345560_2 ribonuclease inhibitor activity - - - 0.0000000000000000000000000000000000000000000000000000000001125 209.0
TLS2_k127_2345560_3 TonB-dependent receptor - - - 0.00000000000000000000000000000003751 135.0
TLS2_k127_2364022_0 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 535.0
TLS2_k127_2364022_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 433.0
TLS2_k127_2364022_2 Sugar (and other) transporter K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 403.0
TLS2_k127_2364022_3 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 379.0
TLS2_k127_2364022_4 Aldo/keto reductase family - - - 0.0000000000000000000000000691 112.0
TLS2_k127_2408791_0 - - - - 0.0000000000000000000000001209 121.0
TLS2_k127_2408791_1 Protein of unknown function (DUF4011) - - - 0.0003156 53.0
TLS2_k127_2433870_0 PFAM aminotransferase, class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 382.0
TLS2_k127_2433870_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000001445 158.0
TLS2_k127_2445275_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 454.0
TLS2_k127_2445275_1 transport system periplasmic component - - - 0.00000000000000000000000000000000000000000000000001389 191.0
TLS2_k127_2445275_2 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000441 116.0
TLS2_k127_2445275_3 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 0.0000000001513 63.0
TLS2_k127_2452875_0 Protein of unknown function DUF116 - - - 1.057e-226 714.0
TLS2_k127_2452875_1 beta-subunit of geranylgeranyltransferase or farnesyltransferase K05956 - 2.5.1.60 0.00000000000000000000001554 115.0
TLS2_k127_2461864_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 496.0
TLS2_k127_2461864_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000227 162.0
TLS2_k127_2461864_2 Belongs to the peptidase S8 family K20276 - - 0.000000000001003 72.0
TLS2_k127_2495984_0 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 458.0
TLS2_k127_2495984_1 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000000000000000000000000000000004068 196.0
TLS2_k127_2495984_2 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000003812 191.0
TLS2_k127_2496318_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 333.0
TLS2_k127_2496318_1 YCII-related domain - - - 0.000000000000000000000000000000000000004796 150.0
TLS2_k127_2496318_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000001154 112.0
TLS2_k127_2496318_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000001743 96.0
TLS2_k127_2496318_4 - - - - 0.0000000000000002009 84.0
TLS2_k127_2497590_0 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004446 291.0
TLS2_k127_2497590_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000001027 94.0
TLS2_k127_2497590_2 Peptidase family M48 - - - 0.000002302 55.0
TLS2_k127_2512663_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.826e-273 852.0
TLS2_k127_2512663_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.156e-219 692.0
TLS2_k127_2512663_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000002802 112.0
TLS2_k127_255755_0 Cytochrome c - - - 0.0 1057.0
TLS2_k127_255755_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 432.0
TLS2_k127_255755_10 - - - - 0.00000003456 64.0
TLS2_k127_255755_2 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 342.0
TLS2_k127_255755_3 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 338.0
TLS2_k127_255755_4 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 331.0
TLS2_k127_255755_5 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000003991 231.0
TLS2_k127_255755_6 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000001664 139.0
TLS2_k127_255755_7 Exopolysaccharide synthesis, ExoD - - - 0.00000000000000000000000000000001163 133.0
TLS2_k127_255755_8 Putative heavy-metal-binding - - - 0.00000000000000000000000000000005434 133.0
TLS2_k127_2582822_0 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 617.0
TLS2_k127_2582822_1 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 377.0
TLS2_k127_2582822_10 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 4.2.99.18 0.00000000000000000000000000000000000000000000009376 183.0
TLS2_k127_2582822_11 PFAM regulatory protein ArsR K21903 - - 0.000000000000000000000000000005205 123.0
TLS2_k127_2582822_12 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000006769 131.0
TLS2_k127_2582822_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000002959 119.0
TLS2_k127_2582822_14 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.000000000724 63.0
TLS2_k127_2582822_16 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000005545 57.0
TLS2_k127_2582822_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 351.0
TLS2_k127_2582822_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 295.0
TLS2_k127_2582822_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001791 277.0
TLS2_k127_2582822_5 Alanyl-tRNA synthetase K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003069 283.0
TLS2_k127_2582822_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001586 280.0
TLS2_k127_2582822_7 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000257 284.0
TLS2_k127_2582822_8 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009796 268.0
TLS2_k127_2582822_9 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001423 264.0
TLS2_k127_2593707_0 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 374.0
TLS2_k127_2593707_1 Amidohydrolase K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 351.0
TLS2_k127_2593707_2 Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 299.0
TLS2_k127_2593707_3 Sigma-54 interaction domain protein K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001267 258.0
TLS2_k127_2593707_4 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000146 194.0
TLS2_k127_2607704_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 617.0
TLS2_k127_2607704_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000003605 178.0
TLS2_k127_2609859_0 domain protein K03455 - - 2.628e-214 689.0
TLS2_k127_2609859_1 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 529.0
TLS2_k127_2609859_2 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 427.0
TLS2_k127_2609859_3 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000003738 167.0
TLS2_k127_2610535_0 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 302.0
TLS2_k127_2610535_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 300.0
TLS2_k127_2610535_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007414 292.0
TLS2_k127_26113_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1161.0
TLS2_k127_26113_1 Na+/H+ antiporter family K03315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 555.0
TLS2_k127_26113_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000003293 180.0
TLS2_k127_26113_11 ABC-type dipeptide oligopeptide nickel transport K00759,K02033 - 2.4.2.7 0.000000000000000000000000000000000000000003069 169.0
TLS2_k127_26113_12 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.00000000000000000000000000000000338 132.0
TLS2_k127_26113_13 NlpC/P60 family K13694,K21471 - 3.4.17.13 0.000000000000000000000000000001845 126.0
TLS2_k127_26113_14 - - - - 0.00000000000005502 82.0
TLS2_k127_26113_15 Putative zinc- or iron-chelating domain - - - 0.0000000000007628 77.0
TLS2_k127_26113_16 Acetyltransferase (GNAT) domain - - - 0.00000001857 63.0
TLS2_k127_26113_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 361.0
TLS2_k127_26113_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 332.0
TLS2_k127_26113_4 extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 323.0
TLS2_k127_26113_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002612 264.0
TLS2_k127_26113_6 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007717 256.0
TLS2_k127_26113_7 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000381 241.0
TLS2_k127_26113_8 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000003755 214.0
TLS2_k127_26113_9 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000002693 198.0
TLS2_k127_2619073_0 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 319.0
TLS2_k127_2619073_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 333.0
TLS2_k127_2619073_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 301.0
TLS2_k127_2619073_3 - - - - 0.000000000000000000000000000000000000000000000000000000000001461 220.0
TLS2_k127_2619073_4 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000009285 182.0
TLS2_k127_2619073_5 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000009984 158.0
TLS2_k127_2619073_6 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000295 103.0
TLS2_k127_2619073_7 metal-dependent phosphoesterases (PHP family) - - - 0.00000000000002311 86.0
TLS2_k127_2619073_8 - - - - 0.000001808 57.0
TLS2_k127_2619168_0 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009835 287.0
TLS2_k127_2619168_1 PEGA domain - - - 0.000002263 59.0
TLS2_k127_2624438_0 Domain of unknown function (DUF4142) - - - 1.903e-207 663.0
TLS2_k127_2624438_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 474.0
TLS2_k127_2624438_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 379.0
TLS2_k127_2624438_3 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane K02761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 371.0
TLS2_k127_2624438_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 326.0
TLS2_k127_2624438_5 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000228 270.0
TLS2_k127_2624438_6 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000000000000006127 158.0
TLS2_k127_2624438_7 Putative restriction endonuclease - - - 0.00000000003381 66.0
TLS2_k127_2624438_8 Putative restriction endonuclease - - - 0.000003411 54.0
TLS2_k127_2624438_9 PFAM Acetyltransferase (GNAT) family - - - 0.000003989 49.0
TLS2_k127_2639906_0 Male sterility protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 361.0
TLS2_k127_2639906_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 343.0
TLS2_k127_2639906_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000006902 143.0
TLS2_k127_2639906_3 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000004289 81.0
TLS2_k127_2640615_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 304.0
TLS2_k127_2640615_1 SMART HTH transcriptional regulator, Crp - - - 0.000000000000000000000000000000000000009305 155.0
TLS2_k127_2640615_2 cheY-homologous receiver domain - - - 0.000000000001604 77.0
TLS2_k127_2729596_0 MacB-like periplasmic core domain - - - 1e-323 1012.0
TLS2_k127_2729596_1 AcrB/AcrD/AcrF family K03296 - - 2.147e-309 974.0
TLS2_k127_2729596_2 Cystathionine beta-synthase K01697 - 4.2.1.22 1.905e-203 647.0
TLS2_k127_2729596_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 421.0
TLS2_k127_2729596_4 Pfam Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 363.0
TLS2_k127_2729596_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009557 278.0
TLS2_k127_2729596_6 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000003751 212.0
TLS2_k127_2729596_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000003916 211.0
TLS2_k127_2729596_8 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000005892 146.0
TLS2_k127_2729596_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000001077 146.0
TLS2_k127_2770166_0 Spermine/spermidine synthase domain - - - 1.48e-271 859.0
TLS2_k127_2770166_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 529.0
TLS2_k127_2770166_10 protein conserved in bacteria K09800 - - 0.00000000000000000000004419 117.0
TLS2_k127_2770166_11 - - - - 0.0000000000000000004622 99.0
TLS2_k127_2770166_13 sarp family - - - 0.00000000005836 77.0
TLS2_k127_2770166_14 CHAT domain - - - 0.000000518 64.0
TLS2_k127_2770166_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 458.0
TLS2_k127_2770166_3 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 415.0
TLS2_k127_2770166_4 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000001769 225.0
TLS2_k127_2770166_5 - - - - 0.0000000000000000000000000000000000000002438 155.0
TLS2_k127_2770166_6 - - - - 0.0000000000000000000000000000000000002404 156.0
TLS2_k127_2770166_7 Surface antigen K07277 - - 0.000000000000000000000000000000000001391 151.0
TLS2_k127_2770166_8 Protein of unknown function (DUF3810) - - - 0.000000000000000000000000001594 124.0
TLS2_k127_2770166_9 GtrA-like protein - - - 0.00000000000000000000002435 113.0
TLS2_k127_2809418_0 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000002684 138.0
TLS2_k127_2809418_2 ABC transporter, transmembrane K18889 - - 0.000001948 51.0
TLS2_k127_2810951_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008304 274.0
TLS2_k127_2810951_1 - - - - 0.0000009989 58.0
TLS2_k127_2825969_0 WHG domain - - - 0.00000000000004039 76.0
TLS2_k127_2842623_0 arylsulfatase activity - - - 3.842e-255 803.0
TLS2_k127_2842623_1 MreB/Mbl protein - - - 4.563e-219 701.0
TLS2_k127_2842623_2 DNA-K related protein - - - 9.275e-208 678.0
TLS2_k127_2842623_3 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 482.0
TLS2_k127_2842623_4 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000000322 174.0
TLS2_k127_2842623_5 Domain of unknown function (DUF2760) - - - 0.00000000000000000000000000000000003792 145.0
TLS2_k127_2842623_6 oxidoreductase activity - - - 0.00000000000000001334 98.0
TLS2_k127_2842623_7 Protein kinase domain K12132 - 2.7.11.1 0.000001229 52.0
TLS2_k127_2843812_0 Domain of unknown function (DUF362) - - - 5.301e-224 699.0
TLS2_k127_2843812_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 401.0
TLS2_k127_2843812_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006373 285.0
TLS2_k127_2843812_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003103 297.0
TLS2_k127_2843812_4 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.00000000000000000005365 91.0
TLS2_k127_2843812_5 Glycosyl transferases group 1 - - - 0.00000000000006836 74.0
TLS2_k127_2850814_0 Methyltransferase type 11 - - - 0.0000000000000000000000000000004853 128.0
TLS2_k127_2852773_0 lipopolysaccharide transport K22110 - - 0.0 1371.0
TLS2_k127_2852773_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 498.0
TLS2_k127_2852773_2 Transport and Golgi organisation 2 K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 460.0
TLS2_k127_2852773_3 SMART Phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 464.0
TLS2_k127_2852773_4 Protein of unknown function (DUF2585) - - - 0.000000000000000000000000000000000000000000000000000000000000001182 225.0
TLS2_k127_2852773_5 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000000000002247 215.0
TLS2_k127_2852773_6 Transport and Golgi organisation 2 K01755 - 4.3.2.1 0.000000000000000000000000000000000000002075 155.0
TLS2_k127_2852773_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000003865 142.0
TLS2_k127_2852773_8 - - - - 0.000000000000000000000000000007631 133.0
TLS2_k127_2852773_9 - - - - 0.000000000000000004542 97.0
TLS2_k127_2854338_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.743e-275 864.0
TLS2_k127_2854338_1 Insulinase (Peptidase family M16) K07263 - - 5.268e-207 676.0
TLS2_k127_2854338_2 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002825 279.0
TLS2_k127_2854338_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008242 246.0
TLS2_k127_2854338_4 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000005802 233.0
TLS2_k127_2854338_5 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000001158 114.0
TLS2_k127_2854338_6 Carboxypeptidase regulatory-like domain - - - 0.000000000000000002614 91.0
TLS2_k127_2854967_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.08e-225 721.0
TLS2_k127_2854967_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 416.0
TLS2_k127_2854967_10 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001339 239.0
TLS2_k127_2854967_11 lyase activity K03301 - - 0.000000000000000000000000000000000000000000000000000000000000003811 246.0
TLS2_k127_2854967_12 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000193 220.0
TLS2_k127_2854967_13 Phosphate acyltransferases K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000002969 198.0
TLS2_k127_2854967_14 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000003746 201.0
TLS2_k127_2854967_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000002439 169.0
TLS2_k127_2854967_16 pfam gaf K08968 - 1.8.4.14 0.000000000000000000000000000000000001376 143.0
TLS2_k127_2854967_17 HD domain - - - 0.00000000000000000000000000000000002078 141.0
TLS2_k127_2854967_18 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000006783 115.0
TLS2_k127_2854967_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 390.0
TLS2_k127_2854967_3 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 374.0
TLS2_k127_2854967_4 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 376.0
TLS2_k127_2854967_5 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 356.0
TLS2_k127_2854967_6 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 306.0
TLS2_k127_2854967_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 305.0
TLS2_k127_2854967_8 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000003887 265.0
TLS2_k127_2854967_9 ATP:ADP antiporter activity K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000005874 267.0
TLS2_k127_2856979_0 pyrroloquinoline quinone binding - - - 2.097e-246 797.0
TLS2_k127_2856979_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 2.37e-230 741.0
TLS2_k127_2856979_10 Alpha/beta-hydrolase family N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003203 273.0
TLS2_k127_2856979_11 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000006479 248.0
TLS2_k127_2856979_12 Alpha/beta-hydrolase family N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000007992 229.0
TLS2_k127_2856979_13 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000002765 213.0
TLS2_k127_2856979_14 Gaf domain K01768,K11527,K18967,K21009 - 2.7.13.3,2.7.7.65,4.6.1.1 0.00000000000000000000000000000000000000000000000002333 205.0
TLS2_k127_2856979_15 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000008511 179.0
TLS2_k127_2856979_16 - - - - 0.0000000000000000000001457 109.0
TLS2_k127_2856979_17 Tetratricopeptide repeat - - - 0.0000000000000004857 90.0
TLS2_k127_2856979_18 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000001603 76.0
TLS2_k127_2856979_19 Putative restriction endonuclease - - - 0.00000000000007114 78.0
TLS2_k127_2856979_2 ACT domain K12524 - 1.1.1.3,2.7.2.4 8.678e-227 731.0
TLS2_k127_2856979_20 transcriptional regulator, winged helix family - - - 0.00000001572 58.0
TLS2_k127_2856979_21 Tat (Twin-arginine translocation) pathway signal sequence domain protein - - - 0.0000004605 59.0
TLS2_k127_2856979_22 Alpha/beta-hydrolase family - - - 0.0000415 51.0
TLS2_k127_2856979_3 choline dehydrogenase activity - - - 4.696e-207 659.0
TLS2_k127_2856979_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 576.0
TLS2_k127_2856979_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 580.0
TLS2_k127_2856979_6 esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 505.0
TLS2_k127_2856979_7 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 476.0
TLS2_k127_2856979_8 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 473.0
TLS2_k127_2856979_9 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 442.0
TLS2_k127_2857397_0 ASPIC and UnbV - - - 3.723e-204 655.0
TLS2_k127_2857397_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 496.0
TLS2_k127_2857397_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000001045 207.0
TLS2_k127_2857397_3 Tetratricopeptide repeat - - - 0.000000000000005185 89.0
TLS2_k127_2865256_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K05962 - 2.7.13.1 0.0000000000000000000000000000000000000000000000000000000000009467 230.0
TLS2_k127_2865256_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000002264 220.0
TLS2_k127_2866892_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.795e-270 854.0
TLS2_k127_2866892_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 517.0
TLS2_k127_2866892_2 tyrosine recombinase XerC K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000246 271.0
TLS2_k127_2866892_3 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000005198 235.0
TLS2_k127_2866892_4 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000006758 220.0
TLS2_k127_2866892_5 tetratricopeptide repeat K02717 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015979,GO:0016020,GO:0016043,GO:0019684,GO:0022607,GO:0031976,GO:0031984,GO:0034357,GO:0034622,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0048564,GO:0055035,GO:0065003,GO:0071840 - 0.000000001037 65.0
TLS2_k127_2875428_0 Histidinol phosphatase and related hydrolases of the PHP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 509.0
TLS2_k127_2875428_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 502.0
TLS2_k127_2875428_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000008206 214.0
TLS2_k127_2875428_3 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000001288 188.0
TLS2_k127_2875428_4 - - - - 0.000000000000000000000000007875 123.0
TLS2_k127_2875428_5 ACT domain protein - - - 0.00000000001503 70.0
TLS2_k127_2875428_6 - - - - 0.0002471 53.0
TLS2_k127_2883165_0 Esterase lipase thioesterase family active site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 561.0
TLS2_k127_2897938_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 6.066e-250 789.0
TLS2_k127_2897938_1 Fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 418.0
TLS2_k127_2897938_2 Bacterial transcriptional regulator K13641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006439 278.0
TLS2_k127_2897938_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000001982 239.0
TLS2_k127_2897938_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000001972 212.0
TLS2_k127_2897938_5 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000008593 180.0
TLS2_k127_2897938_6 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000007483 149.0
TLS2_k127_2897938_7 - - - - 0.000000000000006932 86.0
TLS2_k127_2906819_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 347.0
TLS2_k127_2906819_1 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009082 284.0
TLS2_k127_2906819_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000002657 220.0
TLS2_k127_2906819_3 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000861 196.0
TLS2_k127_2906819_4 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000009438 162.0
TLS2_k127_2906819_5 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000005324 130.0
TLS2_k127_2906819_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000001609 101.0
TLS2_k127_2910568_0 Membrane-bound dehydrogenase domain protein - - - 0.0 1757.0
TLS2_k127_2910568_1 Oligoendopeptidase f - - - 2.058e-254 804.0
TLS2_k127_2910568_2 Pyrrolo-quinoline quinone K00117 - 1.1.5.2 6.938e-194 625.0
TLS2_k127_2910568_3 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 357.0
TLS2_k127_2910568_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 350.0
TLS2_k127_2910568_5 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 316.0
TLS2_k127_2910568_6 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001851 271.0
TLS2_k127_2910568_7 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001499 235.0
TLS2_k127_2910568_8 response to acidic pH K08996 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000002682 155.0
TLS2_k127_2915289_0 Putative glucoamylase K13688 - - 0.0 2342.0
TLS2_k127_2915289_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 2.709e-301 939.0
TLS2_k127_2915289_10 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 351.0
TLS2_k127_2915289_11 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 331.0
TLS2_k127_2915289_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 312.0
TLS2_k127_2915289_13 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 292.0
TLS2_k127_2915289_14 TIGRFAM tripartite ATP-independent periplasmic transporter solute receptor, DctP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005329 267.0
TLS2_k127_2915289_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000004999 233.0
TLS2_k127_2915289_16 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000002857 207.0
TLS2_k127_2915289_17 PFAM tRNA rRNA methyltransferase, SpoU - - - 0.000000000000000000000000000000000000000000000000001108 194.0
TLS2_k127_2915289_18 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000002159 181.0
TLS2_k127_2915289_19 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000003413 184.0
TLS2_k127_2915289_2 C-terminal, D2-small domain, of ClpB protein K03694 - - 9.793e-258 816.0
TLS2_k127_2915289_20 - - - - 0.0000000000000000000000000000000000000000347 158.0
TLS2_k127_2915289_21 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000005434 162.0
TLS2_k127_2915289_22 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000003621 164.0
TLS2_k127_2915289_23 signal peptide processing K03100 - 3.4.21.89 0.00000000000000000000000000000000001907 142.0
TLS2_k127_2915289_24 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000000000000000207 156.0
TLS2_k127_2915289_25 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000763 147.0
TLS2_k127_2915289_26 DinB superfamily - - - 0.0000000000000000000000000000001171 139.0
TLS2_k127_2915289_27 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000002803 126.0
TLS2_k127_2915289_28 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000668 121.0
TLS2_k127_2915289_29 nUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.0000000000000000000000000006718 126.0
TLS2_k127_2915289_3 SPTR Membrane-bound dehydrogenase domain protein - - - 6.531e-245 790.0
TLS2_k127_2915289_30 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000001937 99.0
TLS2_k127_2915289_31 - - - - 0.0000000003911 67.0
TLS2_k127_2915289_32 Putative regulatory protein - - - 0.00000002064 58.0
TLS2_k127_2915289_33 Acetyltransferase (GNAT) family - - - 0.00002336 54.0
TLS2_k127_2915289_4 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 526.0
TLS2_k127_2915289_5 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 447.0
TLS2_k127_2915289_6 Alanine racemase, N-terminal domain K18425,K19967 - 4.1.2.42,4.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 425.0
TLS2_k127_2915289_7 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 415.0
TLS2_k127_2915289_8 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 418.0
TLS2_k127_2915289_9 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 355.0
TLS2_k127_2917022_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.394e-267 830.0
TLS2_k127_2917022_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000009011 85.0
TLS2_k127_2917808_0 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002072 271.0
TLS2_k127_2917808_1 binding domain, Protein - - - 0.0000000000000000000000000000002752 132.0
TLS2_k127_2917808_2 lactoylglutathione lyase activity - - - 0.0000000000000001359 84.0
TLS2_k127_2918743_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 447.0
TLS2_k127_2918743_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 372.0
TLS2_k127_2918743_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000001242 94.0
TLS2_k127_2918743_11 Evidence 5 No homology to any previously reported sequences - - - 0.00002071 57.0
TLS2_k127_2918743_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 351.0
TLS2_k127_2918743_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 334.0
TLS2_k127_2918743_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 314.0
TLS2_k127_2918743_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 306.0
TLS2_k127_2918743_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000297 267.0
TLS2_k127_2918743_7 Pfam Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000992 249.0
TLS2_k127_2918743_8 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000005582 234.0
TLS2_k127_2918743_9 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000009099 150.0
TLS2_k127_2922295_0 Enoyl-(Acyl carrier protein) reductase K16216 - 1.1.1.320 0.000000000000000000000001055 113.0
TLS2_k127_2922295_1 Protein of unknown function (DUF3037) - - - 0.000000000000000009085 84.0
TLS2_k127_2922295_2 Bacterial protein of unknown function (DUF937) - - - 0.0001312 47.0
TLS2_k127_2928441_0 HypF finger K04656 - - 1.151e-250 830.0
TLS2_k127_2928441_1 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 606.0
TLS2_k127_2928441_2 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 464.0
TLS2_k127_2928441_3 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 447.0
TLS2_k127_2928441_4 COG0378 Ni2 -binding GTPase involved in regulation of expression and maturation of urease and hydrogenase K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001001 288.0
TLS2_k127_2928441_5 TIGRFAM hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000448 164.0
TLS2_k127_2928441_6 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000008802 133.0
TLS2_k127_2928441_7 HupF/HypC family K04653 - - 0.0000000000000000000000000000006944 124.0
TLS2_k127_2928441_8 Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - 0.00000000000000000000783 94.0
TLS2_k127_2928441_9 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000003615 95.0
TLS2_k127_2931868_0 efflux transmembrane transporter activity - - - 8.312e-247 796.0
TLS2_k127_2931868_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 610.0
TLS2_k127_2931868_10 negative regulation of transcription, DNA-templated K10947 - - 0.000000000000000000000000000001031 129.0
TLS2_k127_2931868_2 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 547.0
TLS2_k127_2931868_3 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 497.0
TLS2_k127_2931868_4 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 455.0
TLS2_k127_2931868_5 Belongs to the TelA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 434.0
TLS2_k127_2931868_6 response regulator - - - 0.000000000000000000000000000000000000000000000001494 179.0
TLS2_k127_2931868_7 PFAM 5-bromo-4-chloroindolyl phosphate hydrolysis protein - - - 0.00000000000000000000000000000000000000195 168.0
TLS2_k127_2931868_8 Cytochrome c, class I K08738 - - 0.00000000000000000000000000000000000009485 152.0
TLS2_k127_2931868_9 O-methyltransferase activity - - - 0.0000000000000000000000000000000000006571 152.0
TLS2_k127_2933981_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.603e-312 968.0
TLS2_k127_2933981_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.73e-229 740.0
TLS2_k127_2933981_10 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007484 291.0
TLS2_k127_2933981_11 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000005286 215.0
TLS2_k127_2933981_12 von Willebrand factor, type A K07114,K12511 - - 0.00000000000000000000000000000000001333 152.0
TLS2_k127_2933981_13 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000001645 132.0
TLS2_k127_2933981_14 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000001721 132.0
TLS2_k127_2933981_15 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000001247 133.0
TLS2_k127_2933981_16 BON domain - - - 0.000000000000000005012 92.0
TLS2_k127_2933981_17 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.00002366 55.0
TLS2_k127_2933981_18 - - - - 0.00005483 53.0
TLS2_k127_2933981_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 2.314e-203 640.0
TLS2_k127_2933981_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 554.0
TLS2_k127_2933981_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 485.0
TLS2_k127_2933981_5 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 381.0
TLS2_k127_2933981_6 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 350.0
TLS2_k127_2933981_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 343.0
TLS2_k127_2933981_8 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 341.0
TLS2_k127_2933981_9 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008463 330.0
TLS2_k127_2938180_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 586.0
TLS2_k127_2938180_1 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 379.0
TLS2_k127_2938180_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006199 259.0
TLS2_k127_2938180_3 SMART von Willebrand factor, type A K07161 - - 0.000000000000001526 83.0
TLS2_k127_2940230_0 serine-type peptidase activity K01278 - 3.4.14.5 2.581e-262 831.0
TLS2_k127_2940230_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 461.0
TLS2_k127_2940230_10 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000001567 82.0
TLS2_k127_2940230_12 Helix-turn-helix domain - - - 0.00000000000001727 83.0
TLS2_k127_2940230_2 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 348.0
TLS2_k127_2940230_3 ErfK YbiS YcfS YnhG family protein K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 345.0
TLS2_k127_2940230_4 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000001405 266.0
TLS2_k127_2940230_5 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000009735 183.0
TLS2_k127_2940230_6 dUTP diphosphatase activity K01520,K13038 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 0.00000000000000000000000000000000007857 139.0
TLS2_k127_2940230_7 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000029 121.0
TLS2_k127_2940230_8 cheY-homologous receiver domain - - - 0.000000000000000001868 99.0
TLS2_k127_2940230_9 Acetyltransferase (GNAT) family - - - 0.00000000000000004053 96.0
TLS2_k127_2956861_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 454.0
TLS2_k127_2956861_1 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 346.0
TLS2_k127_2956861_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000382 72.0
TLS2_k127_2956861_3 NmrA-like family - - - 0.0000000003574 62.0
TLS2_k127_2956861_4 SnoaL-like polyketide cyclase - - - 0.0001952 50.0
TLS2_k127_2958661_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 317.0
TLS2_k127_2958661_1 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.00000000000000000000000000000000000000000000000000000001263 220.0
TLS2_k127_2958661_2 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000004407 187.0
TLS2_k127_2958661_3 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000001972 173.0
TLS2_k127_2958661_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000005626 183.0
TLS2_k127_2958661_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.0004845 45.0
TLS2_k127_2972818_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 328.0
TLS2_k127_2988235_0 Asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase) K03842 GO:0000030,GO:0003674,GO:0003824,GO:0004578,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006464,GO:0006486,GO:0006487,GO:0006488,GO:0006490,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0012505,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019187,GO:0019538,GO:0031984,GO:0034645,GO:0036211,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0070085,GO:0071704,GO:0097502,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.142 0.000000000000000000000000000000000000000000000000000000000000000000000000000002978 278.0
TLS2_k127_2988235_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000002358 192.0
TLS2_k127_2988235_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000004314 180.0
TLS2_k127_2988235_3 COG1020 Non-ribosomal peptide synthetase modules and related proteins K16126,K21780 GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 - 0.00000000002808 64.0
TLS2_k127_2990073_0 peptidase S41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 386.0
TLS2_k127_2990073_1 dihydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000002617 207.0
TLS2_k127_2990073_2 - - - - 0.00000000000000000000000000000000000000002244 166.0
TLS2_k127_2990073_3 Glycosyl hydrolases family 32 K03332 - 3.2.1.80 0.00000000000000000000000000000000000006684 145.0
TLS2_k127_2990073_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.0000000000000000000000000001421 121.0
TLS2_k127_2990073_6 Alpha/beta hydrolase family - - - 0.0000000000000000000002648 106.0
TLS2_k127_2990073_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000003236 69.0
TLS2_k127_2990073_8 Glycosyl hydrolases family 32 K03332 - 3.2.1.80 0.0000000000009037 73.0
TLS2_k127_2990073_9 enterobactin catabolic process K07214 - - 0.00002939 48.0
TLS2_k127_3004628_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 540.0
TLS2_k127_3004628_1 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000001194 117.0
TLS2_k127_3009870_0 GAF domain K01768 - 4.6.1.1 3.634e-271 894.0
TLS2_k127_3009870_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 548.0
TLS2_k127_3009870_2 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 461.0
TLS2_k127_3009870_3 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 385.0
TLS2_k127_3009870_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 372.0
TLS2_k127_3009870_5 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000001393 193.0
TLS2_k127_3009870_6 - - - - 0.000000000000000000000001883 104.0
TLS2_k127_3009870_7 - - - - 0.0000000001723 72.0
TLS2_k127_3009870_8 - - - - 0.000001816 61.0
TLS2_k127_3009870_9 Putative zinc-finger - - - 0.000004253 54.0
TLS2_k127_3031086_0 Putative Na+/H+ antiporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 555.0
TLS2_k127_3031086_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 559.0
TLS2_k127_3031086_10 - - - - 0.00000000000000000000000000000002934 137.0
TLS2_k127_3031086_11 SnoaL-like domain - - - 0.000000000000000000000000001424 119.0
TLS2_k127_3031086_12 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000004801 118.0
TLS2_k127_3031086_13 protein conserved in cyanobacteria - - - 0.0000000000000000000006712 98.0
TLS2_k127_3031086_14 Orotidine 5'-phosphate decarboxylase / HUMPS family K08093 - 4.1.2.43 0.0000000005892 70.0
TLS2_k127_3031086_2 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 542.0
TLS2_k127_3031086_3 TonB-dependent receptor K02014,K16089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 438.0
TLS2_k127_3031086_4 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 365.0
TLS2_k127_3031086_5 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 306.0
TLS2_k127_3031086_6 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 308.0
TLS2_k127_3031086_7 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 290.0
TLS2_k127_3031086_8 Lytic murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006198 283.0
TLS2_k127_3031086_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000002439 139.0
TLS2_k127_3037568_0 DNA topological change - - - 2.327e-244 782.0
TLS2_k127_3037568_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000008448 68.0
TLS2_k127_3049011_0 oxidoreductase activity - - - 0.0000000000000007538 91.0
TLS2_k127_3049011_1 - - - - 0.00000000171 71.0
TLS2_k127_3056579_0 amine dehydrogenase activity K17285 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 456.0
TLS2_k127_3056579_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 392.0
TLS2_k127_3056579_2 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000001265 181.0
TLS2_k127_3056579_3 Rhodanese-like domain K01069 - 3.1.2.6 0.00000000000000000000000000000000000000003801 153.0
TLS2_k127_3056579_4 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000004071 164.0
TLS2_k127_3056579_5 mttA/Hcf106 family K03116 - - 0.0000000000000375 79.0
TLS2_k127_3056579_6 Peptidase inhibitor I78 family - - - 0.00000000001743 69.0
TLS2_k127_3056579_7 Prenyltransferase K13277 - - 0.0000000001049 74.0
TLS2_k127_3056579_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000001899 57.0
TLS2_k127_3056579_9 Late embryogenesis abundant protein - - - 0.000002504 56.0
TLS2_k127_3058419_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 396.0
TLS2_k127_3058419_1 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 387.0
TLS2_k127_3058419_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000009231 196.0
TLS2_k127_3058419_3 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000003059 190.0
TLS2_k127_3058419_4 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000001317 122.0
TLS2_k127_3058419_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000001227 65.0
TLS2_k127_3060483_0 Cytochrome c - - - 9.809e-247 795.0
TLS2_k127_3060483_1 cobalamin-transporting ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 370.0
TLS2_k127_3060483_2 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000001693 122.0
TLS2_k127_3062479_0 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 446.0
TLS2_k127_3062479_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000001702 216.0
TLS2_k127_3067931_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 1.534e-251 802.0
TLS2_k127_3067931_1 Rubrerythrin K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 341.0
TLS2_k127_3067931_2 protein tyrosine kinase activity K03593 - - 0.00000000000000000000000000000000000001106 156.0
TLS2_k127_3067931_4 FR47-like protein K03789 - 2.3.1.128 0.000001135 61.0
TLS2_k127_3071984_0 Gluconate K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 422.0
TLS2_k127_3071984_1 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 327.0
TLS2_k127_3071984_2 Domain of Unknown Function (DUF1080) - - - 0.0000000016 64.0
TLS2_k127_3076258_0 Rhamnulose-1-phosphate aldolase alcohol dehydrogenase - - - 1.122e-320 996.0
TLS2_k127_3076258_1 Multicopper oxidase - - - 8.941e-302 939.0
TLS2_k127_3076258_10 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 407.0
TLS2_k127_3076258_11 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 364.0
TLS2_k127_3076258_12 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009464 318.0
TLS2_k127_3076258_13 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007283 285.0
TLS2_k127_3076258_14 ATPase domain of DNA mismatch repair MUTS family K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001712 260.0
TLS2_k127_3076258_15 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001495 241.0
TLS2_k127_3076258_16 MafB19-like deaminase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000001903 238.0
TLS2_k127_3076258_17 Peptidase M56, BlaR1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000008829 251.0
TLS2_k127_3076258_18 PFAM Rhodanese domain protein K03892 - - 0.000000000000000000000000000000000000000000000000000000000000000001601 233.0
TLS2_k127_3076258_19 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000001392 213.0
TLS2_k127_3076258_2 beta-galactosidase activity K01190,K01219,K12308 - 3.2.1.23,3.2.1.81 5.138e-235 746.0
TLS2_k127_3076258_20 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000007758 197.0
TLS2_k127_3076258_21 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000001707 181.0
TLS2_k127_3076258_22 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000008141 181.0
TLS2_k127_3076258_23 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000009311 169.0
TLS2_k127_3076258_24 DinB family - - - 0.00000000000000000000000000000000000000000005194 166.0
TLS2_k127_3076258_25 Glycine cleavage system regulatory protein - - - 0.0000000000000000000000000000000000000000001561 169.0
TLS2_k127_3076258_26 Domain of unknown function (DUF4281) - - - 0.00000000000000000000000000000000001324 143.0
TLS2_k127_3076258_27 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000007097 142.0
TLS2_k127_3076258_28 Rieske [2Fe-2S] domain K03886 - - 0.0000000000000000000000005837 112.0
TLS2_k127_3076258_29 Peptidase dimerisation domain - - - 0.0000000000000000000000009062 117.0
TLS2_k127_3076258_3 Amidohydrolase family - - - 2.04e-220 698.0
TLS2_k127_3076258_30 PIN domain - - - 0.00000000000000000000005482 104.0
TLS2_k127_3076258_31 - - - - 0.0000000000000000006224 100.0
TLS2_k127_3076258_32 Nitronate monooxygenase - - - 0.0000000000000009872 80.0
TLS2_k127_3076258_33 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000002014 86.0
TLS2_k127_3076258_34 Protein kinase domain K12132 - 2.7.11.1 0.000000000003149 67.0
TLS2_k127_3076258_35 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000004565 78.0
TLS2_k127_3076258_36 Cytochrome c - - - 0.00000001371 69.0
TLS2_k127_3076258_37 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000002526 55.0
TLS2_k127_3076258_39 PFAM Bacterial regulatory proteins, tetR family - - - 0.000003728 54.0
TLS2_k127_3076258_4 Domain of unknown function (DUF4976) - - - 2.856e-207 652.0
TLS2_k127_3076258_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 563.0
TLS2_k127_3076258_6 Protein of unknown function (DUF819) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 495.0
TLS2_k127_3076258_7 Bacterial fructose-1,6-bisphosphatase, glpX-encoded - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 488.0
TLS2_k127_3076258_8 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 466.0
TLS2_k127_3076258_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 428.0
TLS2_k127_3076663_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 549.0
TLS2_k127_3076663_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 521.0
TLS2_k127_3076663_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 510.0
TLS2_k127_3076663_3 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 466.0
TLS2_k127_3076663_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 467.0
TLS2_k127_3076663_5 Protein of unknown function (DUF1698) K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 366.0
TLS2_k127_3076663_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 362.0
TLS2_k127_3076663_7 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 355.0
TLS2_k127_3076663_8 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 302.0
TLS2_k127_3113737_0 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 596.0
TLS2_k127_3113737_1 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 576.0
TLS2_k127_3113737_10 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 358.0
TLS2_k127_3113737_11 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002518 289.0
TLS2_k127_3113737_12 2-keto-3-deoxy-L-rhamnonate aldolase activity K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000002809 246.0
TLS2_k127_3113737_13 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000002013 248.0
TLS2_k127_3113737_14 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000006409 203.0
TLS2_k127_3113737_15 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000001566 207.0
TLS2_k127_3113737_16 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000005854 176.0
TLS2_k127_3113737_17 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000001626 152.0
TLS2_k127_3113737_18 PFAM PIN domain - - - 0.000000000000000000000000000000003254 136.0
TLS2_k127_3113737_19 Transcriptional regulator PadR-like family - - - 0.0000000000000000003272 91.0
TLS2_k127_3113737_2 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 553.0
TLS2_k127_3113737_20 DNA-templated transcription, initiation K02405 - - 0.000000000000000007157 93.0
TLS2_k127_3113737_21 Protein tyrosine kinase - - - 0.0000000000000004969 84.0
TLS2_k127_3113737_22 Biopolymer K03561 - - 0.000000000000007137 85.0
TLS2_k127_3113737_23 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000006942 78.0
TLS2_k127_3113737_24 TIGRFAM TonB K03832 - - 0.00000000124 69.0
TLS2_k127_3113737_25 Activator of Hsp90 ATPase 1 family protein - - - 0.00000296 56.0
TLS2_k127_3113737_26 Ribbon-helix-helix protein, copG family - - - 0.0000166 49.0
TLS2_k127_3113737_27 nuclear chromosome segregation - - - 0.0002157 50.0
TLS2_k127_3113737_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 554.0
TLS2_k127_3113737_4 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 507.0
TLS2_k127_3113737_5 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 479.0
TLS2_k127_3113737_6 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 474.0
TLS2_k127_3113737_7 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 433.0
TLS2_k127_3113737_8 PFAM Alcohol dehydrogenase zinc-binding domain protein K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 370.0
TLS2_k127_3113737_9 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 363.0
TLS2_k127_3125965_0 Amylo-alpha-1,6-glucosidase - - - 7.092e-204 655.0
TLS2_k127_3125965_1 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 528.0
TLS2_k127_3125965_2 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 344.0
TLS2_k127_3125965_3 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008039 282.0
TLS2_k127_3125965_4 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000007941 139.0
TLS2_k127_3125965_6 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0008703 43.0
TLS2_k127_3146158_0 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 502.0
TLS2_k127_3146158_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 461.0
TLS2_k127_3146158_2 Male sterility protein K12454 - 5.1.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 455.0
TLS2_k127_3146158_3 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000003134 135.0
TLS2_k127_3146158_4 ArsR family transcriptional regulator K22043 - - 0.0000001097 58.0
TLS2_k127_3147044_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1110.0
TLS2_k127_3147044_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1092.0
TLS2_k127_3147044_10 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 494.0
TLS2_k127_3147044_11 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 496.0
TLS2_k127_3147044_12 COG2610 H gluconate symporter and related permeases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 405.0
TLS2_k127_3147044_13 Alkane 1-monooxygenase K00496 - 1.14.15.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 308.0
TLS2_k127_3147044_14 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 305.0
TLS2_k127_3147044_15 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 298.0
TLS2_k127_3147044_16 Copper resistance protein B precursor (CopB) K07233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 291.0
TLS2_k127_3147044_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002911 278.0
TLS2_k127_3147044_18 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008554 256.0
TLS2_k127_3147044_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000003145 234.0
TLS2_k127_3147044_2 Cytochrome c - - - 3.708e-294 927.0
TLS2_k127_3147044_20 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000001014 236.0
TLS2_k127_3147044_21 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000348 219.0
TLS2_k127_3147044_23 COG1309 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000008171 179.0
TLS2_k127_3147044_24 His Kinase A (phosphoacceptor) domain K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000005413 188.0
TLS2_k127_3147044_25 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K03585 - - 0.00000000000000000000000000000000000000000000005855 183.0
TLS2_k127_3147044_26 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000007248 173.0
TLS2_k127_3147044_27 Cupin domain - - - 0.000000000000000000000000000000000000004552 154.0
TLS2_k127_3147044_28 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000782 142.0
TLS2_k127_3147044_29 negative regulation of transcription, DNA-templated K10947 - - 0.00000000000000000000000000004849 121.0
TLS2_k127_3147044_3 Multi-copper - - - 4.471e-287 895.0
TLS2_k127_3147044_30 Thioredoxin-like - - - 0.000000000000000000000007084 107.0
TLS2_k127_3147044_31 outer membrane efflux protein K03287 - - 0.00000000000000000000004374 114.0
TLS2_k127_3147044_32 alginic acid biosynthetic process K01729 - 4.2.2.3 0.0000000000000000001678 99.0
TLS2_k127_3147044_33 pfam yhs - - - 0.000000000000001885 76.0
TLS2_k127_3147044_34 - - - - 0.000000000000003215 87.0
TLS2_k127_3147044_35 Alpha beta hydrolase - - - 0.00000000000004648 83.0
TLS2_k127_3147044_36 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000001044 76.0
TLS2_k127_3147044_37 PFAM PEGA domain - - - 0.0000000002272 73.0
TLS2_k127_3147044_39 alcohol dehydrogenase - - - 0.0000000008425 70.0
TLS2_k127_3147044_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.288e-273 881.0
TLS2_k127_3147044_40 PFAM Forkhead-associated - - - 0.00000001686 64.0
TLS2_k127_3147044_41 Ribbon-helix-helix protein, copG family - - - 0.000005122 53.0
TLS2_k127_3147044_5 TonB-dependent Receptor Plug Domain K02014 - - 1.53e-200 650.0
TLS2_k127_3147044_6 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 592.0
TLS2_k127_3147044_7 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 589.0
TLS2_k127_3147044_8 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 582.0
TLS2_k127_3147044_9 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 525.0
TLS2_k127_3152979_0 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 437.0
TLS2_k127_3152979_1 ABC-type Fe3 transport system permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 363.0
TLS2_k127_3152979_2 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 326.0
TLS2_k127_3152979_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000004779 244.0
TLS2_k127_3152979_4 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000001575 114.0
TLS2_k127_3152979_5 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000296 78.0
TLS2_k127_3152979_6 DinB superfamily - - - 0.0000000000000341 85.0
TLS2_k127_3152979_7 von Willebrand factor (vWF) type A domain - - - 0.000001045 61.0
TLS2_k127_3152979_8 Endonuclease/Exonuclease/phosphatase family K18353 - - 0.0007861 52.0
TLS2_k127_3175222_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 443.0
TLS2_k127_3175222_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000002068 74.0
TLS2_k127_3175222_2 B12 binding domain - - - 0.00000000006466 69.0
TLS2_k127_3175222_3 Radical SAM - - - 0.000001024 53.0
TLS2_k127_3175222_4 Uncharacterised protein family UPF0047 - - - 0.00002507 46.0
TLS2_k127_3177840_0 PFAM lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 317.0
TLS2_k127_3177840_1 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 303.0
TLS2_k127_3177840_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000002679 226.0
TLS2_k127_3177840_3 PIN domain K18828 - - 0.000000000000000000009533 97.0
TLS2_k127_3177840_4 PFAM intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.00000000000000000001236 92.0
TLS2_k127_3177840_5 Putative antitoxin - - - 0.000000000000003592 78.0
TLS2_k127_3189824_0 Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 329.0
TLS2_k127_3189824_1 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001945 244.0
TLS2_k127_3189824_2 DinB superfamily - - - 0.0000000000000000000000000000003324 132.0
TLS2_k127_3189824_3 xylanase chitin deacetylase - - - 0.0000006466 55.0
TLS2_k127_3202521_0 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 552.0
TLS2_k127_3202521_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 393.0
TLS2_k127_3202969_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 309.0
TLS2_k127_3202969_1 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003473 264.0
TLS2_k127_3202969_2 enoyl-coa hydratase carnithine racemase K15513 - 4.1.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000004402 246.0
TLS2_k127_3202969_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891,K15546 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000003186 222.0
TLS2_k127_3223015_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 434.0
TLS2_k127_3223015_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 372.0
TLS2_k127_3223015_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000001502 201.0
TLS2_k127_3223015_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.000000000000001074 80.0
TLS2_k127_3245438_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 456.0
TLS2_k127_3245438_1 Major facilitator K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 462.0
TLS2_k127_3245438_2 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 352.0
TLS2_k127_3245438_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 298.0
TLS2_k127_3245438_4 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000001902 245.0
TLS2_k127_3245438_5 - K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000004905 233.0
TLS2_k127_3245438_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000007883 201.0
TLS2_k127_3245438_7 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000008074 212.0
TLS2_k127_3245438_8 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000006927 157.0
TLS2_k127_3245438_9 Phospholipid methyltransferase - - - 0.0000001206 59.0
TLS2_k127_3279175_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 448.0
TLS2_k127_3279175_1 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 348.0
TLS2_k127_3279175_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000002071 211.0
TLS2_k127_3279175_3 Thioredoxin - - - 0.0000000000000000001388 97.0
TLS2_k127_3285916_0 Membrane-bound dehydrogenase domain protein - - - 0.0 1150.0
TLS2_k127_3285916_1 PFAM PBS lyase HEAT domain protein - - - 0.0 1041.0
TLS2_k127_3285916_10 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000668 136.0
TLS2_k127_3285916_11 Phosphoenolpyruvate hydrolase-like - - - 0.00000000000000000000000000009311 117.0
TLS2_k127_3285916_12 - - - - 0.00000000000000003015 94.0
TLS2_k127_3285916_14 Histidine kinase - - - 0.000000001142 65.0
TLS2_k127_3285916_15 ECF sigma factor K03088 - - 0.00000001992 63.0
TLS2_k127_3285916_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 441.0
TLS2_k127_3285916_3 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000001578 207.0
TLS2_k127_3285916_4 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000008982 205.0
TLS2_k127_3285916_5 GAF domain - - - 0.0000000000000000000000000000000000000002567 172.0
TLS2_k127_3285916_6 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000009505 154.0
TLS2_k127_3285916_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000001287 145.0
TLS2_k127_3285916_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000002056 138.0
TLS2_k127_3285916_9 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000005904 149.0
TLS2_k127_3304449_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 301.0
TLS2_k127_3304449_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003899 255.0
TLS2_k127_3304449_2 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000003051 85.0
TLS2_k127_3326647_0 Heat shock 70 kDa protein K04043 - - 7.357e-292 908.0
TLS2_k127_3326647_1 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 610.0
TLS2_k127_3326647_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000003501 165.0
TLS2_k127_3326647_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 422.0
TLS2_k127_3326647_3 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 332.0
TLS2_k127_3326647_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 331.0
TLS2_k127_3326647_5 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 327.0
TLS2_k127_3326647_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005806 282.0
TLS2_k127_3326647_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000772 226.0
TLS2_k127_3326647_8 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000002386 157.0
TLS2_k127_3326647_9 FecR protein - - - 0.0000000000000000000000000000000000000006969 170.0
TLS2_k127_3327551_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 520.0
TLS2_k127_3327551_1 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000002768 191.0
TLS2_k127_3343494_0 transport - - - 9.824e-211 695.0
TLS2_k127_3343494_1 carboxylic acid catabolic process K01684 - 4.2.1.6 0.00000000000000000000000000000000332 130.0
TLS2_k127_3366191_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 557.0
TLS2_k127_3366191_1 - - - - 0.000000000000000000000000000000000000000000000000000000000061 223.0
TLS2_k127_3366191_2 COG3005 Nitrate TMAO K15876 - - 0.000000000000000000000000000000000000000000000000001324 189.0
TLS2_k127_3373119_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.425e-250 780.0
TLS2_k127_3373119_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.601e-203 641.0
TLS2_k127_3373119_10 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000002033 240.0
TLS2_k127_3373119_11 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000002629 211.0
TLS2_k127_3373119_12 methyltransferase K16048 - - 0.00000000000000000000000000000000000000000000001848 181.0
TLS2_k127_3373119_13 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000009649 151.0
TLS2_k127_3373119_14 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000002851 153.0
TLS2_k127_3373119_15 Biotin-requiring enzyme - - - 0.0000000000000003511 93.0
TLS2_k127_3373119_16 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000003732 73.0
TLS2_k127_3373119_17 Fibronectin type 3 domain - - - 0.0000000002009 75.0
TLS2_k127_3373119_18 - - - - 0.000000001408 69.0
TLS2_k127_3373119_19 TonB dependent receptor - - - 0.0000001245 62.0
TLS2_k127_3373119_2 - - - - 8.984e-202 651.0
TLS2_k127_3373119_3 Pfam:CPSase_L_chain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 458.0
TLS2_k127_3373119_4 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 299.0
TLS2_k127_3373119_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 286.0
TLS2_k127_3373119_6 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001646 291.0
TLS2_k127_3373119_7 surface antigen variable number - - - 0.000000000000000000000000000000000000000000000000000000000000000000001091 270.0
TLS2_k127_3373119_8 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000008864 254.0
TLS2_k127_3373119_9 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000002162 239.0
TLS2_k127_3381387_0 PFAM Radical SAM - - - 2.925e-218 690.0
TLS2_k127_3381387_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000007616 215.0
TLS2_k127_3381387_2 Copper amine oxidase, N2 domain K00276 - 1.4.3.21 0.000000000000000000000000000000000000002394 148.0
TLS2_k127_3382638_0 Protein of unknown function (DUF1553) - - - 0.0 1149.0
TLS2_k127_3382638_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 7.818e-216 700.0
TLS2_k127_3382638_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 545.0
TLS2_k127_3382638_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 314.0
TLS2_k127_3382638_4 - - - - 0.000000000000008819 84.0
TLS2_k127_3382638_5 - - - - 0.0000000005658 64.0
TLS2_k127_3382638_6 Antibiotic biosynthesis monooxygenase - - - 0.000001545 57.0
TLS2_k127_3392309_0 PFAM Type II secretion system protein E K02652 - - 3.727e-227 716.0
TLS2_k127_3392309_1 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 492.0
TLS2_k127_3392309_2 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 308.0
TLS2_k127_3392309_3 PFAM microcompartments protein K04027 - - 0.0000000000000000000000000000000003712 147.0
TLS2_k127_3392309_4 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000001183 138.0
TLS2_k127_3392309_5 Pilus assembly protein K02662 - - 0.000000000000000001072 102.0
TLS2_k127_3392309_7 PFAM Fimbrial assembly family protein K02663 - - 0.000001925 58.0
TLS2_k127_3392309_8 - - - - 0.0008379 49.0
TLS2_k127_3401610_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1532.0
TLS2_k127_3401633_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1029.0
TLS2_k127_3410438_0 Cytochrome C - - - 2.512e-237 760.0
TLS2_k127_3410438_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 556.0
TLS2_k127_3410438_2 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 431.0
TLS2_k127_3410438_3 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 403.0
TLS2_k127_3410438_4 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001698 274.0
TLS2_k127_3410438_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000123 248.0
TLS2_k127_3410438_6 abc transporter atp-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000004858 245.0
TLS2_k127_3410438_7 COGs COG0673 dehydrogenase and related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005786 243.0
TLS2_k127_3410438_8 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000002459 217.0
TLS2_k127_3410438_9 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000002601 181.0
TLS2_k127_3443357_0 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003738 282.0
TLS2_k127_3443357_1 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000002125 172.0
TLS2_k127_3443357_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000005153 155.0
TLS2_k127_3443357_3 Histone-lysine N-methyltransferase K09186 - 2.1.1.43 0.00000000000000003362 84.0
TLS2_k127_3443357_5 ABC transporter, transmembrane K18889 - - 0.00009176 48.0
TLS2_k127_3492970_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 5.542e-262 814.0
TLS2_k127_3492970_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 580.0
TLS2_k127_3492970_10 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000005079 228.0
TLS2_k127_3492970_11 Bacteriocin-protection protein - - - 0.00000000000000000000000000000000000000000000000000000000003917 224.0
TLS2_k127_3492970_12 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000109 207.0
TLS2_k127_3492970_13 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000003926 201.0
TLS2_k127_3492970_14 PFAM Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000000000002217 219.0
TLS2_k127_3492970_15 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000005381 211.0
TLS2_k127_3492970_16 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000004662 166.0
TLS2_k127_3492970_17 response to abiotic stimulus - - - 0.000000000000000000000000000000000000004097 156.0
TLS2_k127_3492970_18 lactoylglutathione lyase activity - - - 0.0000000000000000000001034 106.0
TLS2_k127_3492970_19 Tetratricopeptide repeat - - - 0.000000000000000002161 97.0
TLS2_k127_3492970_2 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 554.0
TLS2_k127_3492970_20 Phosphoserine phosphatase - - - 0.000000002539 69.0
TLS2_k127_3492970_21 Domain of unknown function (DUF4142) K08995 - - 0.0000001472 59.0
TLS2_k127_3492970_3 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 466.0
TLS2_k127_3492970_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 407.0
TLS2_k127_3492970_5 Methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 366.0
TLS2_k127_3492970_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 344.0
TLS2_k127_3492970_7 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 314.0
TLS2_k127_3492970_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002272 283.0
TLS2_k127_3492970_9 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000007036 252.0
TLS2_k127_3509238_0 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 7.211e-285 906.0
TLS2_k127_3509238_1 Rhodanese-like domain K01069 - 3.1.2.6 3.723e-213 671.0
TLS2_k127_3509238_2 PFAM Molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 439.0
TLS2_k127_3509238_3 2Fe-2S -binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 293.0
TLS2_k127_3509238_4 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005544 263.0
TLS2_k127_3509238_5 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0005787 45.0
TLS2_k127_3545438_0 peptidase K07386 - - 1.827e-306 959.0
TLS2_k127_3545438_1 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 494.0
TLS2_k127_3545438_2 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 470.0
TLS2_k127_3545438_3 Permease family K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 388.0
TLS2_k127_3545438_4 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000001713 237.0
TLS2_k127_3545438_5 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000009623 195.0
TLS2_k127_3545438_6 von Willebrand factor, type A K07114 - - 0.0000000000000000000000004721 118.0
TLS2_k127_3545438_7 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000003386 93.0
TLS2_k127_3545438_8 Periplasmic or secreted lipoprotein - - - 0.0000000000000009561 86.0
TLS2_k127_35502_0 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 421.0
TLS2_k127_35502_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000009376 202.0
TLS2_k127_35502_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000148 161.0
TLS2_k127_35502_3 PFAM O-Antigen ligase K07234 - - 0.000002405 60.0
TLS2_k127_3563683_0 MacB-like periplasmic core domain - - - 2.448e-195 640.0
TLS2_k127_3563683_1 phosphate symporter K14683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001309 281.0
TLS2_k127_3563683_2 PhoU domain - - - 0.00000000000000004457 89.0
TLS2_k127_3563683_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885 - 6.1.1.17 0.00001749 48.0
TLS2_k127_3591723_0 SNF2 family N-terminal domain - - - 1.442e-264 856.0
TLS2_k127_3591723_1 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000007632 116.0
TLS2_k127_3591723_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000001031 72.0
TLS2_k127_3600363_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 390.0
TLS2_k127_3600363_1 peptidase activity - - - 0.00000000000000000002444 102.0
TLS2_k127_3603166_0 Gluconolactonase K01053,K14274 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 557.0
TLS2_k127_3603166_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 306.0
TLS2_k127_3603166_2 Major facilitator Superfamily K08218,K08223 - - 0.00000000000000000000000000000000000000000002082 176.0
TLS2_k127_3630425_0 eight transmembrane protein EpsH - - - 0.000000000000000000000000000000000000000000000000000000000006892 220.0
TLS2_k127_3630425_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000136 233.0
TLS2_k127_3630425_2 Peptidase, M23 family - - - 0.000000000000000000000000000000000000000007196 166.0
TLS2_k127_3630425_3 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000000000000000000001079 158.0
TLS2_k127_3652005_0 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 573.0
TLS2_k127_3652005_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 301.0
TLS2_k127_3656972_0 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 505.0
TLS2_k127_3656972_1 FGGY family of carbohydrate kinases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 411.0
TLS2_k127_3690298_0 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 614.0
TLS2_k127_3690298_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 546.0
TLS2_k127_3690298_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000002311 219.0
TLS2_k127_3690298_3 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000001224 114.0
TLS2_k127_369956_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.296e-209 665.0
TLS2_k127_369956_1 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 400.0
TLS2_k127_369956_2 - - - - 0.0000000000000000000000000000001183 131.0
TLS2_k127_369956_3 Adenylate cyclase - - - 0.000000000000006083 88.0
TLS2_k127_369956_4 COG1520 FOG WD40-like repeat - - - 0.0000002364 63.0
TLS2_k127_369956_5 Methicillin resistance protein - - - 0.00008661 49.0
TLS2_k127_369956_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0002204 49.0
TLS2_k127_3729203_0 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006895 284.0
TLS2_k127_3729203_1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008183 292.0
TLS2_k127_3729203_2 Oxidoreductase family, C-terminal alpha beta domain K03810 - - 0.000000004619 57.0
TLS2_k127_3729203_3 Outer membrane protein (OmpH-like) K06142 - - 0.00000002081 63.0
TLS2_k127_3729203_4 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000698 50.0
TLS2_k127_3743257_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 499.0
TLS2_k127_3743257_1 Cytochrome c K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 464.0
TLS2_k127_3743257_2 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 377.0
TLS2_k127_3743257_3 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 343.0
TLS2_k127_3743257_4 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 321.0
TLS2_k127_3743257_5 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003592 271.0
TLS2_k127_3743257_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000004617 247.0
TLS2_k127_3743257_7 PFAM Rieske 2Fe-2S domain K03886 - - 0.00000000000000000000000000000000000000000000003058 176.0
TLS2_k127_3772680_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1114.0
TLS2_k127_3772680_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 8.097e-221 706.0
TLS2_k127_3772680_10 oxidoreductase activity - - - 0.00000000000000000000001187 118.0
TLS2_k127_3772680_11 Transcriptional regulatory protein, C terminal - - - 0.00000001483 66.0
TLS2_k127_3772680_12 PRC-barrel domain - - - 0.0009515 51.0
TLS2_k127_3772680_2 Ribosomal protein S1 K02945 - - 9.162e-210 668.0
TLS2_k127_3772680_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 552.0
TLS2_k127_3772680_4 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 521.0
TLS2_k127_3772680_5 Dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 326.0
TLS2_k127_3772680_6 Cobalamin B12-binding K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000003685 196.0
TLS2_k127_3772680_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000002229 194.0
TLS2_k127_3772680_8 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000001073 191.0
TLS2_k127_3772680_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000001314 141.0
TLS2_k127_3782250_0 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 0.0000000000000000000003367 106.0
TLS2_k127_3782250_1 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000004247 104.0
TLS2_k127_3784860_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 573.0
TLS2_k127_3784860_1 Glycosyl hydrolases family 43 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 422.0
TLS2_k127_3784860_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 389.0
TLS2_k127_3784860_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000002263 209.0
TLS2_k127_3784860_4 - - - - 0.000000000000008431 82.0
TLS2_k127_3784957_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 476.0
TLS2_k127_3784957_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 413.0
TLS2_k127_3784957_10 oxidoreductase activity - - - 0.000000000001446 81.0
TLS2_k127_3784957_11 O-antigen ligase - - - 0.000000004178 70.0
TLS2_k127_3784957_12 ATP-independent chaperone mediated protein folding K06006 - - 0.00004154 54.0
TLS2_k127_3784957_2 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 412.0
TLS2_k127_3784957_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 306.0
TLS2_k127_3784957_4 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000003629 261.0
TLS2_k127_3784957_5 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002581 258.0
TLS2_k127_3784957_6 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000006631 195.0
TLS2_k127_3784957_7 DNA polymerase III K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000006872 201.0
TLS2_k127_3784957_8 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000005682 177.0
TLS2_k127_3784957_9 - - - - 0.00000000000000001542 89.0
TLS2_k127_3796847_0 Peptidase, S9A B C family, catalytic domain protein - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.184e-232 739.0
TLS2_k127_3796847_1 sh3 domain protein - - - 2.773e-198 632.0
TLS2_k127_3796847_10 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 409.0
TLS2_k127_3796847_11 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 370.0
TLS2_k127_3796847_12 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 352.0
TLS2_k127_3796847_13 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 320.0
TLS2_k127_3796847_14 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 303.0
TLS2_k127_3796847_15 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002346 248.0
TLS2_k127_3796847_16 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000002273 189.0
TLS2_k127_3796847_17 ECF sigma factor - - - 0.000000000000000000000000000000000000000005415 162.0
TLS2_k127_3796847_18 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000008482 168.0
TLS2_k127_3796847_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 595.0
TLS2_k127_3796847_20 - - - - 0.00000000000000000000000000000001237 143.0
TLS2_k127_3796847_21 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000001017 112.0
TLS2_k127_3796847_22 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.000000000000000000000002553 113.0
TLS2_k127_3796847_23 HEPN domain - - - 0.00000000000000000000004894 103.0
TLS2_k127_3796847_24 nucleotidyltransferase activity K07061 - - 0.0000000000000000000006487 98.0
TLS2_k127_3796847_25 - - - - 0.00000000000001024 78.0
TLS2_k127_3796847_26 MerC mercury resistance protein - - - 0.0000000000006513 76.0
TLS2_k127_3796847_28 Domain of unknown function (DUF4397) - - - 0.00000001456 65.0
TLS2_k127_3796847_3 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 553.0
TLS2_k127_3796847_30 - - - - 0.000008213 55.0
TLS2_k127_3796847_31 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00001992 49.0
TLS2_k127_3796847_32 Histidine kinase K15011 - 2.7.13.3 0.00003749 51.0
TLS2_k127_3796847_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 510.0
TLS2_k127_3796847_5 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 462.0
TLS2_k127_3796847_6 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 439.0
TLS2_k127_3796847_7 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 439.0
TLS2_k127_3796847_8 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 422.0
TLS2_k127_3796847_9 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 409.0
TLS2_k127_3814122_0 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000009763 171.0
TLS2_k127_3814122_1 - - - - 0.000000000000000000000002865 110.0
TLS2_k127_3816548_0 Belongs to the peptidase S8 family - - - 1.109e-311 976.0
TLS2_k127_3816548_1 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 449.0
TLS2_k127_3816548_2 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000001045 212.0
TLS2_k127_3816548_3 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000001005 214.0
TLS2_k127_3816548_4 Peptidase family S58 - - - 0.0000000000000001511 83.0
TLS2_k127_382966_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 428.0
TLS2_k127_382966_1 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 337.0
TLS2_k127_382966_2 Short-chain dehydrogenase reductase SDR K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 298.0
TLS2_k127_382966_3 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000001712 225.0
TLS2_k127_382966_4 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000002151 225.0
TLS2_k127_382966_5 NIPSNAP family containing protein - - - 0.000000000000000000000000000005215 124.0
TLS2_k127_3841574_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 456.0
TLS2_k127_3841574_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 433.0
TLS2_k127_3841574_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 362.0
TLS2_k127_3841574_3 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 323.0
TLS2_k127_3841574_4 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.0000000000000000009096 102.0
TLS2_k127_3841574_5 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.00000000008684 67.0
TLS2_k127_3841574_6 sigma 54 modulation protein K05808 - - 0.0000000002906 65.0
TLS2_k127_3845476_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.022e-237 746.0
TLS2_k127_3845476_1 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 463.0
TLS2_k127_3845476_10 COG0569 K transport systems NAD-binding component K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 329.0
TLS2_k127_3845476_11 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 323.0
TLS2_k127_3845476_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 298.0
TLS2_k127_3845476_13 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001138 275.0
TLS2_k127_3845476_14 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.0000000000000000000000000000000000000000000000000000000000000000003099 237.0
TLS2_k127_3845476_15 protein flavinylation K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000002339 235.0
TLS2_k127_3845476_16 S1/P1 Nuclease - - - 0.00000000000000000000000000000000000000000000000005164 190.0
TLS2_k127_3845476_17 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000001572 181.0
TLS2_k127_3845476_18 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000001259 182.0
TLS2_k127_3845476_19 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000002466 125.0
TLS2_k127_3845476_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 450.0
TLS2_k127_3845476_22 PRC-barrel domain - - - 0.0000000000000000003539 99.0
TLS2_k127_3845476_23 oxidoreductase activity, acting on CH-OH group of donors - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000002933 93.0
TLS2_k127_3845476_24 - - - - 0.000000000000004801 84.0
TLS2_k127_3845476_25 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000001989 79.0
TLS2_k127_3845476_26 30S ribosomal protein S23 - - - 0.000000003503 63.0
TLS2_k127_3845476_27 domain, Protein - - - 0.00001017 57.0
TLS2_k127_3845476_28 Membrane - - - 0.0001308 55.0
TLS2_k127_3845476_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 453.0
TLS2_k127_3845476_4 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 444.0
TLS2_k127_3845476_5 PFAM Cation K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 426.0
TLS2_k127_3845476_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 398.0
TLS2_k127_3845476_7 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 368.0
TLS2_k127_3845476_8 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 347.0
TLS2_k127_3845476_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 358.0
TLS2_k127_3845623_0 Bacteriophage N4 adsorption protein B K11740 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 3.298e-304 948.0
TLS2_k127_3845623_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.029e-253 796.0
TLS2_k127_3845623_10 Bacteriophage N4 adsorption protein A K11739 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 391.0
TLS2_k127_3845623_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 371.0
TLS2_k127_3845623_12 Predicted membrane protein (DUF2231) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006489 250.0
TLS2_k127_3845623_13 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000002507 261.0
TLS2_k127_3845623_14 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000000000001778 226.0
TLS2_k127_3845623_15 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000001273 207.0
TLS2_k127_3845623_16 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000009585 195.0
TLS2_k127_3845623_17 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000002261 200.0
TLS2_k127_3845623_18 - - - - 0.0000000000000000000000000000000000000000000003125 185.0
TLS2_k127_3845623_19 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000001753 167.0
TLS2_k127_3845623_2 PFAM LmbE family protein K22136 - - 2.125e-247 791.0
TLS2_k127_3845623_20 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000001707 160.0
TLS2_k127_3845623_21 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000002201 144.0
TLS2_k127_3845623_22 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000008252 120.0
TLS2_k127_3845623_23 catechol 1,2-dioxygenase - - - 0.000000000000000000000000003042 115.0
TLS2_k127_3845623_25 Creatinine amidohydrolase - - - 0.00000000000000000000006617 104.0
TLS2_k127_3845623_26 efflux transmembrane transporter activity K02004 - - 0.000000000000000000005007 104.0
TLS2_k127_3845623_27 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000099 72.0
TLS2_k127_3845623_28 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000009615 68.0
TLS2_k127_3845623_29 toxin-antitoxin pair type II binding - - - 0.00000000009707 66.0
TLS2_k127_3845623_3 Two component regulator propeller - - - 9.07e-230 734.0
TLS2_k127_3845623_30 Methyltransferase domain - - - 0.0000005434 60.0
TLS2_k127_3845623_31 CsbD-like - - - 0.000134 47.0
TLS2_k127_3845623_34 SnoaL-like domain - - - 0.0005224 49.0
TLS2_k127_3845623_4 TonB dependent receptor - - - 2.021e-219 715.0
TLS2_k127_3845623_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 541.0
TLS2_k127_3845623_6 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 503.0
TLS2_k127_3845623_7 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 489.0
TLS2_k127_3845623_8 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 462.0
TLS2_k127_3845623_9 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 433.0
TLS2_k127_3855822_0 type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000000000000001056 226.0
TLS2_k127_3855822_1 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000001587 141.0
TLS2_k127_3868651_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 469.0
TLS2_k127_3868651_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005676 266.0
TLS2_k127_3868651_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002852 260.0
TLS2_k127_3868651_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03972 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000000000000004089 96.0
TLS2_k127_3877729_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 427.0
TLS2_k127_3877729_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 314.0
TLS2_k127_3877729_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000003163 63.0
TLS2_k127_3882548_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 519.0
TLS2_k127_3882548_1 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 362.0
TLS2_k127_3882548_2 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 311.0
TLS2_k127_3882548_3 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000001493 117.0
TLS2_k127_3896417_0 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000003298 184.0
TLS2_k127_3896417_1 ethanolamine catabolic process K04027 - - 0.000000000000000000000000000000000000004365 147.0
TLS2_k127_3896417_2 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000004353 114.0
TLS2_k127_3896417_3 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000000002266 101.0
TLS2_k127_3896417_4 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000000002215 93.0
TLS2_k127_3896417_5 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000004377 55.0
TLS2_k127_3934804_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 530.0
TLS2_k127_3934804_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003271 247.0
TLS2_k127_3934804_2 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000003035 162.0
TLS2_k127_3934804_3 COG2825 Outer membrane protein - - - 0.0001834 50.0
TLS2_k127_3934804_4 Sh3 type 3 domain protein - - - 0.0003522 53.0
TLS2_k127_3950542_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.693e-260 810.0
TLS2_k127_3950542_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.145e-201 652.0
TLS2_k127_3950542_10 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000007505 196.0
TLS2_k127_3950542_11 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000001025 155.0
TLS2_k127_3950542_12 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000005081 143.0
TLS2_k127_3950542_13 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.000000000000000000000000000000002324 140.0
TLS2_k127_3950542_14 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000001668 127.0
TLS2_k127_3950542_15 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000002602 102.0
TLS2_k127_3950542_16 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000001112 100.0
TLS2_k127_3950542_17 Heat induced stress protein YflT - - - 0.00000000001817 71.0
TLS2_k127_3950542_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000003992 66.0
TLS2_k127_3950542_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00001389 54.0
TLS2_k127_3950542_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 570.0
TLS2_k127_3950542_20 PFAM sigma-54 factor interaction domain-containing protein K10941 - - 0.0002839 44.0
TLS2_k127_3950542_3 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 435.0
TLS2_k127_3950542_4 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 375.0
TLS2_k127_3950542_5 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 374.0
TLS2_k127_3950542_6 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002788 283.0
TLS2_k127_3950542_7 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002709 265.0
TLS2_k127_3950542_8 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000007678 259.0
TLS2_k127_3950542_9 HD domain - - - 0.00000000000000000000000000000000000000000000000000000004004 213.0
TLS2_k127_3969155_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 492.0
TLS2_k127_3969155_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 464.0
TLS2_k127_3969155_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001487 285.0
TLS2_k127_3969155_3 Preprotein translocase SecG subunit K03075 - - 0.0000000000006774 73.0
TLS2_k127_3981026_0 Patatin-like phospholipase - - - 0.0000000000000000000000000000000002508 153.0
TLS2_k127_3981026_1 - - - - 0.000000000000000000002014 111.0
TLS2_k127_3989280_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 567.0
TLS2_k127_3989280_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001133 286.0
TLS2_k127_3989280_2 Transcriptional regulator PadR-like family - - - 0.00000000000000002226 86.0
TLS2_k127_3989280_3 PFAM blue (type 1) copper domain protein - - - 0.00001327 53.0
TLS2_k127_4003100_0 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 317.0
TLS2_k127_4003100_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001413 274.0
TLS2_k127_4003100_2 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000001201 147.0
TLS2_k127_4003100_3 Protein of unknown function (DUF1593) - - - 0.00009764 46.0
TLS2_k127_4008348_0 Catalase K07217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 593.0
TLS2_k127_4008348_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 552.0
TLS2_k127_4008348_10 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000001182 240.0
TLS2_k127_4008348_11 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005325 258.0
TLS2_k127_4008348_12 UV-endonuclease UvdE - - - 0.0000000000000000000000000000000000000000000000000000000000000002372 233.0
TLS2_k127_4008348_13 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000004568 210.0
TLS2_k127_4008348_14 DinB family - - - 0.000000000000000000000002891 109.0
TLS2_k127_4008348_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000522 108.0
TLS2_k127_4008348_16 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000001048 83.0
TLS2_k127_4008348_17 FtsX-like permease family - - - 0.0000000000328 64.0
TLS2_k127_4008348_18 Predicted membrane protein (DUF2243) - - - 0.0005437 49.0
TLS2_k127_4008348_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 494.0
TLS2_k127_4008348_3 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 488.0
TLS2_k127_4008348_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 507.0
TLS2_k127_4008348_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 418.0
TLS2_k127_4008348_6 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 364.0
TLS2_k127_4008348_7 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 354.0
TLS2_k127_4008348_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 316.0
TLS2_k127_4008348_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003686 251.0
TLS2_k127_4017842_0 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000001282 119.0
TLS2_k127_4017842_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000443 83.0
TLS2_k127_4017842_2 shape-determining protein MreD K03571 - - 0.0001033 54.0
TLS2_k127_404033_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 493.0
TLS2_k127_404033_1 Ankyrin repeat - - - 0.0000000000000000000000000000000008406 141.0
TLS2_k127_4059073_0 ABC transporter C-terminal domain K06158 - - 1.269e-197 637.0
TLS2_k127_4059073_1 response regulator K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000669 261.0
TLS2_k127_4059073_2 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000006396 214.0
TLS2_k127_4059073_3 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001036 209.0
TLS2_k127_4059073_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000007108 150.0
TLS2_k127_4059073_5 Sigma-54 interaction domain - - - 0.0000000000000000000001161 105.0
TLS2_k127_4059073_6 Anti-sigma-K factor rskA - - - 0.0006192 51.0
TLS2_k127_4065301_0 Carboxypeptidase regulatory-like domain - - - 0.0 1338.0
TLS2_k127_4065301_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 496.0
TLS2_k127_4065301_2 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 436.0
TLS2_k127_4065301_3 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 394.0
TLS2_k127_4065301_4 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001314 277.0
TLS2_k127_4065301_5 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000254 207.0
TLS2_k127_4065301_6 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000003558 116.0
TLS2_k127_4068333_0 DEAD DEAH box K03724 - - 0.0 1951.0
TLS2_k127_4068333_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002824 221.0
TLS2_k127_4068333_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000005287 140.0
TLS2_k127_4068333_3 Belongs to the FPG family K05522 - 4.2.99.18 0.0000005764 61.0
TLS2_k127_4075036_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 579.0
TLS2_k127_4075036_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 564.0
TLS2_k127_4075036_12 lipolytic protein G-D-S-L family - - - 0.0000171 57.0
TLS2_k127_4075036_13 - - - - 0.0001221 50.0
TLS2_k127_4075036_2 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 506.0
TLS2_k127_4075036_3 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 468.0
TLS2_k127_4075036_4 membrane protein involved in D-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 432.0
TLS2_k127_4075036_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 354.0
TLS2_k127_4075036_6 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003856 263.0
TLS2_k127_4075036_7 glutathionylspermidine amidase activity K01460 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464 3.5.1.78,6.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000004219 259.0
TLS2_k127_4075036_8 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005601 240.0
TLS2_k127_412485_0 transport - - - 0.0 1365.0
TLS2_k127_4139418_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 340.0
TLS2_k127_4139418_1 Bacterial PH domain - - - 0.00000000000000000000000000000000000252 142.0
TLS2_k127_4146025_0 - - - - 0.00000000000000000000000000000000000000000000000001049 198.0
TLS2_k127_4151578_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000007761 131.0
TLS2_k127_4155393_0 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 626.0
TLS2_k127_4155393_1 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000105 145.0
TLS2_k127_4163144_0 short chain dehydrogenase K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008859 256.0
TLS2_k127_4163144_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000007896 161.0
TLS2_k127_4163144_2 - - - - 0.00000000000000000000000000001804 120.0
TLS2_k127_4163144_3 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.00000000000000000003473 93.0
TLS2_k127_417070_0 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001892 281.0
TLS2_k127_417070_1 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000017 244.0
TLS2_k127_417070_2 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000008768 240.0
TLS2_k127_417070_3 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000005956 192.0
TLS2_k127_4177485_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 288.0
TLS2_k127_4177485_1 Putative zinc- or iron-chelating domain - - - 0.0000000000001134 79.0
TLS2_k127_420276_0 Trehalose utilisation - - - 0.0 1861.0
TLS2_k127_420276_1 Transposase - - - 0.00000000000002716 81.0
TLS2_k127_4214995_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 384.0
TLS2_k127_4214995_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000005608 110.0
TLS2_k127_4215476_0 Belongs to the xylose isomerase family K01805 - 5.3.1.5 3.424e-206 646.0
TLS2_k127_4215476_1 Calcineurin-like phosphoesterase - - - 2.891e-204 653.0
TLS2_k127_4215476_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 405.0
TLS2_k127_4215476_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 355.0
TLS2_k127_4215476_4 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 300.0
TLS2_k127_4215476_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002846 288.0
TLS2_k127_4215476_6 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000007542 237.0
TLS2_k127_4215476_7 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000002402 218.0
TLS2_k127_4215476_8 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000001973 138.0
TLS2_k127_4215476_9 - - - - 0.0000000004025 65.0
TLS2_k127_423725_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009596 455.0
TLS2_k127_423725_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000001498 175.0
TLS2_k127_423725_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000369 141.0
TLS2_k127_4238462_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 510.0
TLS2_k127_4238462_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 347.0
TLS2_k127_4238462_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000002823 196.0
TLS2_k127_4238462_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000004461 136.0
TLS2_k127_4238462_4 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000003655 135.0
TLS2_k127_4238462_5 protein-(glutamine-N5) methyltransferase activity - - - 0.00000000000000000000000000006224 128.0
TLS2_k127_4238462_6 Alpha amylase, catalytic domain K00690 - 2.4.1.7 0.0000000000000000000001166 102.0
TLS2_k127_4238462_7 Glycosyl transferase 4-like domain - - - 0.0000000000000000001116 104.0
TLS2_k127_4238462_8 Glycosyl transferase - - - 0.000000000000000004259 96.0
TLS2_k127_4241923_0 lipopolysaccharide transport K22110 - - 0.0 1041.0
TLS2_k127_4250698_0 Domain of unknown function (DUF3427) - - - 1.228e-221 697.0
TLS2_k127_4250698_1 TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008419 267.0
TLS2_k127_4250698_2 TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000002105 183.0
TLS2_k127_4250698_3 - - - - 0.00000000000000000000000000000000000007114 159.0
TLS2_k127_4250698_4 - - - - 0.000000000000000000000001124 107.0
TLS2_k127_4250698_5 Putative restriction endonuclease - - - 0.0000000000000000000005414 103.0
TLS2_k127_4250698_6 Domain of Unknown Function (DUF1080) - - - 0.000000000004877 66.0
TLS2_k127_4250698_7 PFAM SEC-C motif domain protein - - - 0.000001116 61.0
TLS2_k127_4250791_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 2.464e-201 653.0
TLS2_k127_4250791_1 AMP-binding enzyme K12508 - 6.2.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 611.0
TLS2_k127_4250791_2 Methionine synthase vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 509.0
TLS2_k127_4250791_3 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 377.0
TLS2_k127_4250791_4 protocatechuate 3,4-dioxygenase, beta subunit' K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 354.0
TLS2_k127_4250791_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.0000000000000000000000000000000000000000000000000002101 191.0
TLS2_k127_4250791_6 protocatechuate 3,4-dioxygenase activity K00448 - 1.13.11.3 0.000000000000000000000000000000000000000000000000001275 197.0
TLS2_k127_4294543_0 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 338.0
TLS2_k127_4294543_1 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008823 263.0
TLS2_k127_4294543_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000003027 212.0
TLS2_k127_4294543_3 - - - - 0.0000000000000000000000000000000000005867 146.0
TLS2_k127_4294570_0 Ferrous iron transport protein B C terminus K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 597.0
TLS2_k127_4294570_1 TonB dependent receptor K16089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 486.0
TLS2_k127_4294570_10 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005339 280.0
TLS2_k127_4294570_11 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000128 254.0
TLS2_k127_4294570_12 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000001608 217.0
TLS2_k127_4294570_13 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000000003474 218.0
TLS2_k127_4294570_14 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000000000000002245 215.0
TLS2_k127_4294570_15 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000003801 196.0
TLS2_k127_4294570_16 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000008665 163.0
TLS2_k127_4294570_17 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000004384 157.0
TLS2_k127_4294570_18 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000185 162.0
TLS2_k127_4294570_19 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0034986,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000007962 122.0
TLS2_k127_4294570_2 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 426.0
TLS2_k127_4294570_20 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000004497 129.0
TLS2_k127_4294570_21 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000003698 117.0
TLS2_k127_4294570_22 Redoxin - - - 0.0000000000000000000001708 107.0
TLS2_k127_4294570_23 nitric oxide dioxygenase activity K21405 - - 0.0000000000000000000003622 107.0
TLS2_k127_4294570_24 LamB/YcsF family K07160 - - 0.000000000000002566 77.0
TLS2_k127_4294570_25 BON domain - - - 0.000000000004917 72.0
TLS2_k127_4294570_26 - - - - 0.0000005461 53.0
TLS2_k127_4294570_27 - - - - 0.0000007739 60.0
TLS2_k127_4294570_29 - - - - 0.0008796 48.0
TLS2_k127_4294570_3 Ferrous iron transport protein B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 400.0
TLS2_k127_4294570_4 Deoxyhypusine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 382.0
TLS2_k127_4294570_5 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 380.0
TLS2_k127_4294570_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 364.0
TLS2_k127_4294570_7 Aminotransferase class-V K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 341.0
TLS2_k127_4294570_8 iron ion homeostasis K03322,K03709,K04758 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 323.0
TLS2_k127_4294570_9 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
TLS2_k127_431208_0 cobalamin binding K01847,K01849 - 5.4.99.2 0.0 1096.0
TLS2_k127_431208_1 MacB-like periplasmic core domain - - - 0.0 1030.0
TLS2_k127_431208_10 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000003706 187.0
TLS2_k127_431208_11 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.0000000000000000007028 94.0
TLS2_k127_431208_12 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000004187 68.0
TLS2_k127_431208_2 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 500.0
TLS2_k127_431208_3 ArgK protein K07588 GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 430.0
TLS2_k127_431208_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 431.0
TLS2_k127_431208_5 Methylmalonyl-CoA mutase K01847,K03763,K14447 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944 2.7.7.7,5.4.99.2,5.4.99.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 373.0
TLS2_k127_431208_6 peroxidase K07223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 404.0
TLS2_k127_431208_7 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 345.0
TLS2_k127_431208_8 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 295.0
TLS2_k127_431208_9 Catalase - - - 0.00000000000000000000000000000000000000000000000000000004401 210.0
TLS2_k127_4326754_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 543.0
TLS2_k127_4326754_1 Methylates ribosomal protein L11 K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.0000004717 58.0
TLS2_k127_4342708_0 Glutamate synthase K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1972.0
TLS2_k127_4342708_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 4.315e-284 899.0
TLS2_k127_4342708_10 - - - - 0.000000000000000000000000000000000001949 150.0
TLS2_k127_4342708_11 DinB superfamily - - - 0.000000000000000000000000000000001617 137.0
TLS2_k127_4342708_12 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0000000000000000000000000000001973 138.0
TLS2_k127_4342708_13 acetolactate synthase K01576,K01652 - 2.2.1.6,4.1.1.7 0.000000000000003382 76.0
TLS2_k127_4342708_2 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 2.655e-235 743.0
TLS2_k127_4342708_3 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.871e-218 687.0
TLS2_k127_4342708_4 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 485.0
TLS2_k127_4342708_5 LOR/SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 464.0
TLS2_k127_4342708_6 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 463.0
TLS2_k127_4342708_7 Phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001018 291.0
TLS2_k127_4342708_8 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000004919 266.0
TLS2_k127_4342708_9 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000005666 154.0
TLS2_k127_4344966_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 355.0
TLS2_k127_4344966_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000308 188.0
TLS2_k127_4344966_2 beta-N-acetylglucosaminidase K15719 - 2.3.1.48,3.2.1.169 0.0000000000000000000000000000000006604 136.0
TLS2_k127_4344966_3 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000001137 120.0
TLS2_k127_4347_0 PFAM Peptidoglycan-binding domain 1 protein K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000005192 231.0
TLS2_k127_4347_1 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000008421 113.0
TLS2_k127_4347_2 response regulator K07685 - - 0.0000000000000000000002665 108.0
TLS2_k127_4358551_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 502.0
TLS2_k127_4358551_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 370.0
TLS2_k127_4367179_0 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 448.0
TLS2_k127_4367179_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 459.0
TLS2_k127_4367179_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000009749 224.0
TLS2_k127_4367179_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000011 181.0
TLS2_k127_4367179_4 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000002679 182.0
TLS2_k127_4367179_5 Uncharacterized protein conserved in bacteria (DUF2314) - - - 0.0000000000000000000000000000000000000003158 154.0
TLS2_k127_4367179_6 binding domain, Protein - - - 0.000000000000000000000000000000000000001729 150.0
TLS2_k127_4383977_0 Protein of unknown function (DUF4038) - - - 3.026e-214 674.0
TLS2_k127_4383977_1 cell wall glycoprotein biosynthetic process - - - 1.003e-195 617.0
TLS2_k127_4383977_10 Phosphogluconate dehydrogenase (decarboxylating) C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 327.0
TLS2_k127_4383977_11 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 304.0
TLS2_k127_4383977_12 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002695 280.0
TLS2_k127_4383977_13 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002935 279.0
TLS2_k127_4383977_14 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000003695 142.0
TLS2_k127_4383977_15 Transfers electrons from cytochrome c551 to cytochrome oxidase - GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009767,GO:0009987,GO:0015979,GO:0016020,GO:0019684,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000001542 139.0
TLS2_k127_4383977_16 COG1404 Subtilisin-like serine proteases - - - 0.00000000000000000003489 107.0
TLS2_k127_4383977_17 transporter mgtE K06213 - - 0.00001409 51.0
TLS2_k127_4383977_2 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 536.0
TLS2_k127_4383977_3 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 511.0
TLS2_k127_4383977_4 Fungalysin metallopeptidase (M36) K01417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 497.0
TLS2_k127_4383977_5 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 467.0
TLS2_k127_4383977_6 Type III effector Hrp-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 398.0
TLS2_k127_4383977_7 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 382.0
TLS2_k127_4383977_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 398.0
TLS2_k127_4383977_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000994 351.0
TLS2_k127_4386596_0 Glycogen debranching enzyme N terminal - - - 1.518e-277 876.0
TLS2_k127_4386596_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.506e-238 758.0
TLS2_k127_4386596_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001289 232.0
TLS2_k127_4386596_11 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000004637 207.0
TLS2_k127_4386596_12 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000006765 202.0
TLS2_k127_4386596_13 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000003756 190.0
TLS2_k127_4386596_14 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000009161 171.0
TLS2_k127_4386596_15 ABC transporter K02003 - - 0.00000000000000000000000000000000001626 137.0
TLS2_k127_4386596_16 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000003029 128.0
TLS2_k127_4386596_17 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000884 124.0
TLS2_k127_4386596_18 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000001085 113.0
TLS2_k127_4386596_19 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000008243 108.0
TLS2_k127_4386596_2 Cytochrome c-type biogenesis protein K02198 - - 1.549e-231 747.0
TLS2_k127_4386596_20 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000003922 76.0
TLS2_k127_4386596_22 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000002904 67.0
TLS2_k127_4386596_23 SNARE associated Golgi protein - - - 0.00000000286 66.0
TLS2_k127_4386596_24 YicC-like family, N-terminal region - - - 0.000000009123 65.0
TLS2_k127_4386596_25 - - - - 0.0000001192 62.0
TLS2_k127_4386596_27 Inositol monophosphatase K01092 - 3.1.3.25 0.0005921 45.0
TLS2_k127_4386596_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 520.0
TLS2_k127_4386596_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 494.0
TLS2_k127_4386596_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 430.0
TLS2_k127_4386596_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 359.0
TLS2_k127_4386596_7 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 347.0
TLS2_k127_4386596_8 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 364.0
TLS2_k127_4386596_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 341.0
TLS2_k127_4392558_0 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000003709 170.0
TLS2_k127_4392558_1 protein involved in exopolysaccharide biosynthesis K16554 - - 0.0002408 52.0
TLS2_k127_439585_0 PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 578.0
TLS2_k127_439585_1 Secretion ATPase, PEP-CTERM locus subfamily K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008304 275.0
TLS2_k127_439585_2 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000008139 162.0
TLS2_k127_439585_3 Polysaccharide biosynthesis protein - - - 0.000000000001491 80.0
TLS2_k127_439585_4 Glycosyl transferase family 21 - - - 0.0007844 42.0
TLS2_k127_4403027_0 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005378 285.0
TLS2_k127_4403027_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000001198 237.0
TLS2_k127_4493337_0 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000004208 158.0
TLS2_k127_4493337_1 transglycosylase K08309 - - 0.00004913 55.0
TLS2_k127_452629_0 TonB-dependent receptor - - - 0.0 1240.0
TLS2_k127_452629_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 431.0
TLS2_k127_452629_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 342.0
TLS2_k127_452629_3 O-methyltransferase - - - 0.0000000000000000000000000009516 121.0
TLS2_k127_452629_4 oxidoreductase activity - - - 0.0000000000000000009216 100.0
TLS2_k127_452629_5 Arginase family K01476 - 3.5.3.1 0.0000000000000001071 81.0
TLS2_k127_452629_6 Sensory box histidine kinase response regulator - - - 0.000000000009643 71.0
TLS2_k127_453036_0 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 607.0
TLS2_k127_4534762_0 ABC transporter - - - 2.937e-277 862.0
TLS2_k127_4534762_1 MacB-like periplasmic core domain - - - 6.71e-217 689.0
TLS2_k127_4534762_10 Pfam:UPF0118 K11744 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0009372,GO:0009987,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000007362 247.0
TLS2_k127_4534762_11 - - - - 0.00000000000000000000000000000000000000000000000000000088 199.0
TLS2_k127_4534762_12 - - - - 0.00000000000000000000000000000000000007162 158.0
TLS2_k127_4534762_13 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000385 160.0
TLS2_k127_4534762_14 transcriptional regulator PadR family - - - 0.00000000000000000000000000000004621 128.0
TLS2_k127_4534762_15 Belongs to the sigma-70 factor family K03088 - - 0.0000000000000000000000000004126 114.0
TLS2_k127_4534762_16 - - - - 0.0000000000000000000000008893 111.0
TLS2_k127_4534762_2 Glycosyl hydrolase family 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 572.0
TLS2_k127_4534762_3 radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 495.0
TLS2_k127_4534762_4 Na+/H+ antiporter family K03300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 436.0
TLS2_k127_4534762_5 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 431.0
TLS2_k127_4534762_6 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 415.0
TLS2_k127_4534762_7 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 409.0
TLS2_k127_4534762_8 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 361.0
TLS2_k127_4534762_9 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001297 250.0
TLS2_k127_4537207_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 379.0
TLS2_k127_4537207_1 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000003712 226.0
TLS2_k127_4537207_2 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000009343 105.0
TLS2_k127_457562_0 Domain of unknown function (DUF4976) - - - 3.038e-228 724.0
TLS2_k127_457562_1 acetyltransferase K03827 - - 0.000000000000000000000000000000000000000000000000000000002811 204.0
TLS2_k127_457562_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000004397 135.0
TLS2_k127_457562_3 O-acyltransferase activity - - - 0.00000006972 62.0
TLS2_k127_457562_4 protein related to plant photosystem II stability assembly factor - - - 0.00000009409 64.0
TLS2_k127_4652982_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000001433 237.0
TLS2_k127_4688114_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 6.24e-316 993.0
TLS2_k127_4688114_1 Methionine synthase K00548 - 2.1.1.13 3.195e-206 652.0
TLS2_k127_4688114_2 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 597.0
TLS2_k127_4688114_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 447.0
TLS2_k127_4688114_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 466.0
TLS2_k127_4688114_5 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 439.0
TLS2_k127_4688114_6 COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 376.0
TLS2_k127_4688114_7 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000009985 250.0
TLS2_k127_4688114_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000001881 247.0
TLS2_k127_4688114_9 HlyD membrane-fusion protein of T1SS - - - 0.000000000000000006796 96.0
TLS2_k127_4701134_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001143 243.0
TLS2_k127_4701134_1 ribonuclease activity - - - 0.00000000000000000000000000006824 121.0
TLS2_k127_4701134_2 Protein of unknown function (DUF4038) - - - 0.000000000000000002258 85.0
TLS2_k127_47013_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002127 270.0
TLS2_k127_47013_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000389 239.0
TLS2_k127_47013_2 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000027 234.0
TLS2_k127_47013_3 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000003501 218.0
TLS2_k127_47013_4 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.0000000000000000000000000000000000000000000000007673 188.0
TLS2_k127_47013_5 GrpB protein - - - 0.000000000000000000000000000000000000000000003816 170.0
TLS2_k127_47013_6 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000001354 170.0
TLS2_k127_47013_7 transferase activity, transferring acyl groups K03824 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000002157 164.0
TLS2_k127_47013_8 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000001802 141.0
TLS2_k127_47013_9 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000003322 136.0
TLS2_k127_4703615_0 TIGRFAM iron-sulfur cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 345.0
TLS2_k127_4703615_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 289.0
TLS2_k127_4703615_2 Fe-S oxidoreductase K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006772 253.0
TLS2_k127_4713745_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 533.0
TLS2_k127_4713745_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 393.0
TLS2_k127_4713745_10 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000001594 65.0
TLS2_k127_4713745_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 362.0
TLS2_k127_4713745_3 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003667 260.0
TLS2_k127_4713745_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008559 265.0
TLS2_k127_4713745_5 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000005053 183.0
TLS2_k127_4713745_6 lipid kinase activity - - - 0.00000000000000000000000000000000000002642 156.0
TLS2_k127_4713745_8 - - - - 0.0000000000000000003857 94.0
TLS2_k127_4713745_9 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000001983 65.0
TLS2_k127_4716307_0 protein import - - - 4.251e-238 764.0
TLS2_k127_4716307_1 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 468.0
TLS2_k127_4716307_10 DoxX K16937 - 1.8.5.2 0.00000000000000000000001588 110.0
TLS2_k127_4716307_11 Domain of unknown function (DUF2382) - - - 0.000000000000000000008441 101.0
TLS2_k127_4716307_12 YtkA-like - - - 0.000000000000004636 86.0
TLS2_k127_4716307_13 Membrane - - - 0.0000000000000347 75.0
TLS2_k127_4716307_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 443.0
TLS2_k127_4716307_3 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 425.0
TLS2_k127_4716307_4 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000003357 264.0
TLS2_k127_4716307_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001949 245.0
TLS2_k127_4716307_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000007593 222.0
TLS2_k127_4716307_7 and related - - - 0.00000000000000000000000000000000000000000000000000000000000005294 230.0
TLS2_k127_4716307_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000005642 226.0
TLS2_k127_4716307_9 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000002259 147.0
TLS2_k127_4722434_0 Carboxypeptidase regulatory-like domain - - - 8.843e-273 891.0
TLS2_k127_4722434_1 Cys/Met metabolism PLP-dependent enzyme K01042 - 2.9.1.1 6.988e-205 651.0
TLS2_k127_4722434_10 protein histidine kinase activity - - - 0.0000000000000000000004135 103.0
TLS2_k127_4722434_11 protein conserved in bacteria - - - 0.000000000000001822 79.0
TLS2_k127_4722434_12 Protein of unknown function DUF72 - - - 0.000000000001429 73.0
TLS2_k127_4722434_13 PIN domain - - - 0.000000000006779 67.0
TLS2_k127_4722434_15 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000007245 51.0
TLS2_k127_4722434_16 Protein of unknown function (DUF1059) - - - 0.000006607 51.0
TLS2_k127_4722434_17 pyrroloquinoline quinone binding - - - 0.00001072 49.0
TLS2_k127_4722434_18 Putative collagen-binding domain of a collagenase - - - 0.00009303 49.0
TLS2_k127_4722434_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.794e-198 639.0
TLS2_k127_4722434_3 amidohydrolase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 608.0
TLS2_k127_4722434_4 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 540.0
TLS2_k127_4722434_5 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 417.0
TLS2_k127_4722434_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 385.0
TLS2_k127_4722434_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001522 291.0
TLS2_k127_4722434_8 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000005562 176.0
TLS2_k127_4722434_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000004056 139.0
TLS2_k127_4733703_0 beta-N-acetylglucosaminidase - GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000227 269.0
TLS2_k127_4733703_1 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000005266 186.0
TLS2_k127_4736798_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 591.0
TLS2_k127_4736798_1 Hep Hag repeat protein K01179,K01207 - 3.2.1.4,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 481.0
TLS2_k127_4736798_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009449 460.0
TLS2_k127_4736798_3 CARDB domain-containing protein,subtilase family protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009276 290.0
TLS2_k127_4739627_0 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 1.092e-287 896.0
TLS2_k127_4739627_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 544.0
TLS2_k127_4739627_10 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 349.0
TLS2_k127_4739627_11 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004058 294.0
TLS2_k127_4739627_12 Cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005661 257.0
TLS2_k127_4739627_13 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000005986 239.0
TLS2_k127_4739627_14 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000003883 184.0
TLS2_k127_4739627_15 KR domain K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000007631 171.0
TLS2_k127_4739627_16 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000259 173.0
TLS2_k127_4739627_17 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000000002934 162.0
TLS2_k127_4739627_18 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000003596 140.0
TLS2_k127_4739627_19 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000006223 152.0
TLS2_k127_4739627_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 502.0
TLS2_k127_4739627_20 tRNA wobble adenosine to inosine editing - - - 0.00000000000000000000000000000001039 145.0
TLS2_k127_4739627_21 - - - - 0.00000000000000000000000000000001158 132.0
TLS2_k127_4739627_22 Belongs to the ompA family - - - 0.00000000000000000000000000000002621 134.0
TLS2_k127_4739627_23 - - - - 0.000000000000000000000000000008574 128.0
TLS2_k127_4739627_24 DoxX K15977 - - 0.00000000000000000000000002762 114.0
TLS2_k127_4739627_25 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000004104 83.0
TLS2_k127_4739627_26 - - - - 0.0000000000359 74.0
TLS2_k127_4739627_27 PRC-barrel domain - - - 0.0000000002616 68.0
TLS2_k127_4739627_3 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 485.0
TLS2_k127_4739627_4 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 465.0
TLS2_k127_4739627_5 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 446.0
TLS2_k127_4739627_6 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 437.0
TLS2_k127_4739627_7 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 397.0
TLS2_k127_4739627_8 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 386.0
TLS2_k127_4739627_9 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 337.0
TLS2_k127_4756705_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000427 243.0
TLS2_k127_4756705_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000001809 117.0
TLS2_k127_4764142_0 Glycosyl hydrolases family 15 - - - 3.882e-257 806.0
TLS2_k127_4764142_1 enterobactin catabolic process K07214,K09689 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 499.0
TLS2_k127_4764142_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 377.0
TLS2_k127_4764142_3 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003042 289.0
TLS2_k127_4764142_4 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000001514 228.0
TLS2_k127_4764142_5 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000002265 203.0
TLS2_k127_4764142_6 Protein kinase domain K08884 - 2.7.11.1 0.000000000000000000000000000000001504 142.0
TLS2_k127_4764142_7 domain, Protein - - - 0.0000000000000000000000000008206 131.0
TLS2_k127_4764142_8 - - - - 0.0000000000000000000053 108.0
TLS2_k127_4764142_9 Cupin 2, conserved barrel domain protein - - - 0.000000005812 63.0
TLS2_k127_4776802_0 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 491.0
TLS2_k127_4776802_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 403.0
TLS2_k127_4776802_10 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000007138 143.0
TLS2_k127_4776802_11 repeat-containing protein - - - 0.000000000000000000000000000000713 139.0
TLS2_k127_4776802_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000001523 103.0
TLS2_k127_4776802_13 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000001865 94.0
TLS2_k127_4776802_14 Cold shock K03704 - - 0.000000000000000002733 85.0
TLS2_k127_4776802_15 Trm112p-like protein K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.00000000000000001838 85.0
TLS2_k127_4776802_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000001973 247.0
TLS2_k127_4776802_3 O-Antigen ligase K18814 - - 0.00000000000000000000000000000000000000000000000000006992 209.0
TLS2_k127_4776802_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000005207 186.0
TLS2_k127_4776802_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000001097 177.0
TLS2_k127_4776802_6 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000003039 187.0
TLS2_k127_4776802_7 Glycosyl transferase, family 9 K02843,K02849 - - 0.000000000000000000000000000000000000000000000611 179.0
TLS2_k127_4776802_8 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000002863 158.0
TLS2_k127_4776802_9 Glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000001674 167.0
TLS2_k127_4791998_0 Condensation domain - - - 3.837e-279 930.0
TLS2_k127_4798777_0 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001577 241.0
TLS2_k127_4798777_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000002026 125.0
TLS2_k127_4798777_2 - - - - 0.0000000000000134 76.0
TLS2_k127_4802720_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 512.0
TLS2_k127_4802720_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 505.0
TLS2_k127_4802720_10 dextransucrase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000492 289.0
TLS2_k127_4802720_11 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000006014 222.0
TLS2_k127_4802720_12 PFAM Class II Aldolase and Adducin N-terminal domain K01628,K22130 - 4.1.1.104,4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000001869 222.0
TLS2_k127_4802720_13 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000007432 208.0
TLS2_k127_4802720_14 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000004937 188.0
TLS2_k127_4802720_15 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000003817 179.0
TLS2_k127_4802720_16 - - - - 0.0000000000000000000000000000005971 135.0
TLS2_k127_4802720_17 Nuclear protein SET K07117 - - 0.0000000000000000000009181 101.0
TLS2_k127_4802720_18 - - - - 0.00000000000000000002145 98.0
TLS2_k127_4802720_19 Domain of unknown function (DUF4956) - - - 0.00000335 59.0
TLS2_k127_4802720_2 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 431.0
TLS2_k127_4802720_20 Dienelactone hydrolase family - - - 0.000006458 60.0
TLS2_k127_4802720_3 Dehydrogenase K00052 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 430.0
TLS2_k127_4802720_4 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 407.0
TLS2_k127_4802720_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 390.0
TLS2_k127_4802720_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 327.0
TLS2_k127_4802720_7 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 306.0
TLS2_k127_4802720_8 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 302.0
TLS2_k127_4802720_9 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 294.0
TLS2_k127_4804152_0 Bacterial alpha-L-rhamnosidase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 368.0
TLS2_k127_4804152_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000001595 208.0
TLS2_k127_4804152_2 Cysteine-rich secretory protein family - - - 0.00000000000000000000001772 111.0
TLS2_k127_4813751_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 401.0
TLS2_k127_4813751_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 329.0
TLS2_k127_4813751_2 - - - - 0.00000000000000008021 90.0
TLS2_k127_4813751_3 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.00002443 47.0
TLS2_k127_4817495_0 pyrroloquinoline quinone binding - - - 0.0 1141.0
TLS2_k127_4817495_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 584.0
TLS2_k127_4817495_10 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 312.0
TLS2_k127_4817495_11 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 300.0
TLS2_k127_4817495_12 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004855 264.0
TLS2_k127_4817495_13 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000006373 241.0
TLS2_k127_4817495_14 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000008707 229.0
TLS2_k127_4817495_15 Domain of Unknown Function (DUF1540) - - - 0.00000000000000000000006257 102.0
TLS2_k127_4817495_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 559.0
TLS2_k127_4817495_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 553.0
TLS2_k127_4817495_4 PhoD-like phosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 537.0
TLS2_k127_4817495_5 lactate racemase activity K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 516.0
TLS2_k127_4817495_6 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 464.0
TLS2_k127_4817495_7 InterPro IPR010496 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 389.0
TLS2_k127_4817495_8 alcohol dehydrogenase K00001,K00008 - 1.1.1.1,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 367.0
TLS2_k127_4817495_9 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 323.0
TLS2_k127_4845689_0 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 448.0
TLS2_k127_4845689_1 PFAM Glycosyl transferase, group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 408.0
TLS2_k127_4845689_2 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 323.0
TLS2_k127_4845689_3 Protein tyrosine kinase - - - 0.000000000000000002283 100.0
TLS2_k127_4845689_4 solute binding protein K02035 - - 0.0000000001498 75.0
TLS2_k127_4853277_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 501.0
TLS2_k127_4853277_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000586 229.0
TLS2_k127_4853277_2 ABC transporter transmembrane region K06147 - - 0.0000168 47.0
TLS2_k127_4863532_0 HEAT repeats - - - 3.156e-302 975.0
TLS2_k127_4863532_1 pyrroloquinoline quinone binding - - - 3.569e-281 889.0
TLS2_k127_4863532_2 Belongs to the glycosyl hydrolase 13 family K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 400.0
TLS2_k127_4863532_3 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000009917 216.0
TLS2_k127_4863532_4 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000002858 224.0
TLS2_k127_4863532_5 Trehalose utilisation - - - 0.000000000000000007429 87.0
TLS2_k127_4863532_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000001374 62.0
TLS2_k127_4863532_7 Helix-turn-helix domain K15539 - - 0.00000007776 64.0
TLS2_k127_4863532_8 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000001176 56.0
TLS2_k127_4863532_9 Protein tyrosine kinase K12132 - 2.7.11.1 0.000007308 50.0
TLS2_k127_4865425_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 9.698e-227 715.0
TLS2_k127_4865425_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 388.0
TLS2_k127_4865425_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015233,GO:0015238,GO:0015291,GO:0015293,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0015887,GO:0015893,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072349,GO:0090482,GO:0098656,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 372.0
TLS2_k127_4865425_3 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003376 285.0
TLS2_k127_4865425_4 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003737 231.0
TLS2_k127_4865425_5 tRNA methyltransferase complex GCD14 subunit - - - 0.00000000000000000000000000000000000000000000000001511 192.0
TLS2_k127_4865425_6 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000001985 182.0
TLS2_k127_4867604_0 May be the GTPase, regulating ATP sulfurylase activity K00955 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237 2.7.1.25,2.7.7.4 1.505e-201 639.0
TLS2_k127_4867604_1 inorganic diphosphatase activity K05521 - 3.2.2.24 0.000000000000000000000000000000003843 136.0
TLS2_k127_4882738_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 381.0
TLS2_k127_4882738_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000001167 175.0
TLS2_k127_4882738_2 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000004361 132.0
TLS2_k127_4882738_3 Phosphoribosyl transferase domain - - - 0.00000000000002755 76.0
TLS2_k127_4882738_4 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000005981 64.0
TLS2_k127_4883221_0 Sulfatase-modifying factor enzyme 1 K13444 - 1.8.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 396.0
TLS2_k127_4883221_1 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000006722 172.0
TLS2_k127_4883221_2 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000003359 138.0
TLS2_k127_4883221_3 Glycosyl hydrolase family 57 K22278 - 3.5.1.104 0.0000000000000000000001045 113.0
TLS2_k127_488658_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 361.0
TLS2_k127_488658_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000407 270.0
TLS2_k127_4889700_0 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 327.0
TLS2_k127_4910394_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1179.0
TLS2_k127_4910394_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.233e-278 875.0
TLS2_k127_4910394_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008188 273.0
TLS2_k127_4910394_11 RNA modification enzyme, MiaB family K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000003093 250.0
TLS2_k127_4910394_12 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000184 231.0
TLS2_k127_4910394_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000007405 194.0
TLS2_k127_4910394_14 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000000000001175 149.0
TLS2_k127_4910394_15 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000004374 145.0
TLS2_k127_4910394_16 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000007678 100.0
TLS2_k127_4910394_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000002817 98.0
TLS2_k127_4910394_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 591.0
TLS2_k127_4910394_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 524.0
TLS2_k127_4910394_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 456.0
TLS2_k127_4910394_5 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 435.0
TLS2_k127_4910394_6 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 394.0
TLS2_k127_4910394_7 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 394.0
TLS2_k127_4910394_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 342.0
TLS2_k127_4910394_9 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 336.0
TLS2_k127_4910911_0 Response regulator receiver K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 605.0
TLS2_k127_4910911_1 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 426.0
TLS2_k127_4910911_10 cheY-homologous receiver domain - - - 0.0000000000000000002634 96.0
TLS2_k127_4910911_11 - - - - 0.000000001235 61.0
TLS2_k127_4910911_12 Domain of unknown function (DUF4115) - - - 0.000002529 59.0
TLS2_k127_4910911_2 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 428.0
TLS2_k127_4910911_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 413.0
TLS2_k127_4910911_4 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 393.0
TLS2_k127_4910911_5 membrane K08981 - - 0.0000000000000000000000000000000000000000000000000000000000000001484 242.0
TLS2_k127_4910911_6 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000001053 197.0
TLS2_k127_4910911_7 TIGRFAM TonB K03832 - - 0.0000000000000000000000001811 116.0
TLS2_k127_4910911_8 Bacterial PH domain K09167 - - 0.000000000000000000000004508 110.0
TLS2_k127_4910911_9 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000009738 108.0
TLS2_k127_4912845_0 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 329.0
TLS2_k127_4923126_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 595.0
TLS2_k127_4923126_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 374.0
TLS2_k127_4923126_10 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000889 179.0
TLS2_k127_4923126_11 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000006134 151.0
TLS2_k127_4923126_12 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000000004345 126.0
TLS2_k127_4923126_13 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000009412 128.0
TLS2_k127_4923126_14 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000002012 122.0
TLS2_k127_4923126_15 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000009657 126.0
TLS2_k127_4923126_16 methyltransferase - - - 0.00000000000000000000000001954 124.0
TLS2_k127_4923126_17 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 0.00000000000000000001762 102.0
TLS2_k127_4923126_18 lysyltransferase activity K07027 - - 0.000000000000003761 87.0
TLS2_k127_4923126_19 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000001026 86.0
TLS2_k127_4923126_2 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 350.0
TLS2_k127_4923126_20 - - - - 0.000000005023 70.0
TLS2_k127_4923126_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 340.0
TLS2_k127_4923126_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000001217 245.0
TLS2_k127_4923126_5 O-acyltransferase activity K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000000000000000007143 244.0
TLS2_k127_4923126_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000004459 226.0
TLS2_k127_4923126_7 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000005504 206.0
TLS2_k127_4923126_8 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000005708 204.0
TLS2_k127_4923126_9 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000109 183.0
TLS2_k127_4930835_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.6e-244 784.0
TLS2_k127_4930835_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 434.0
TLS2_k127_4930835_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 307.0
TLS2_k127_4930835_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 294.0
TLS2_k127_4930835_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001292 271.0
TLS2_k127_4930835_5 SMART Transport-associated and nodulation region K04065 - - 0.0006424 50.0
TLS2_k127_4935957_0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351 - - 0.000000000000000000000000000000000000000000000000000000000000000001649 235.0
TLS2_k127_4935957_2 Periplasmic or secreted lipoprotein - - - 0.000000000002768 77.0
TLS2_k127_4935957_3 Calcineurin-like phosphoesterase - - - 0.00003616 50.0
TLS2_k127_4969949_0 Protein of unknown function, DUF255 K06888 - - 4.817e-218 699.0
TLS2_k127_4969949_1 secondary active p-aminobenzoyl-glutamate transmembrane transporter activity K12942 - - 4.507e-207 658.0
TLS2_k127_4969949_10 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000003447 235.0
TLS2_k127_4969949_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000008905 216.0
TLS2_k127_4969949_12 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000447 202.0
TLS2_k127_4969949_13 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000001077 205.0
TLS2_k127_4969949_14 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000003648 194.0
TLS2_k127_4969949_15 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000001651 185.0
TLS2_k127_4969949_16 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000009349 136.0
TLS2_k127_4969949_18 RNA polymerase-binding protein DksA K06204 - - 0.0000000000000001071 85.0
TLS2_k127_4969949_19 Bacterial regulatory protein, Fis family - - - 0.0000000000002784 78.0
TLS2_k127_4969949_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 398.0
TLS2_k127_4969949_20 peptidyl-tyrosine sulfation - - - 0.000000000926 72.0
TLS2_k127_4969949_23 - - - - 0.0008547 52.0
TLS2_k127_4969949_3 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 410.0
TLS2_k127_4969949_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 372.0
TLS2_k127_4969949_5 metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 338.0
TLS2_k127_4969949_6 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 312.0
TLS2_k127_4969949_7 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000769 278.0
TLS2_k127_4969949_8 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004157 252.0
TLS2_k127_4969949_9 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000002197 253.0
TLS2_k127_4971652_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000005107 193.0
TLS2_k127_4977145_0 Copper amine oxidase, N2 domain K00276 - 1.4.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 545.0
TLS2_k127_4977145_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 436.0
TLS2_k127_4977145_2 N-Acyl-D-aspartate D-glutamate deacylase K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000001209 258.0
TLS2_k127_5002661_0 Zn-dependent protease with chaperone function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 327.0
TLS2_k127_5002661_1 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000001593 203.0
TLS2_k127_5002661_2 Participates in the control of copper homeostasis K06201 - - 0.00000000000000000000000000001053 126.0
TLS2_k127_5002661_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000179 68.0
TLS2_k127_5002661_4 - - - - 0.0000754 52.0
TLS2_k127_501191_0 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 508.0
TLS2_k127_501191_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 366.0
TLS2_k127_501191_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000412 123.0
TLS2_k127_501191_11 Belongs to the ompA family K03286 - - 0.0009651 49.0
TLS2_k127_501191_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 347.0
TLS2_k127_501191_3 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 333.0
TLS2_k127_501191_4 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 312.0
TLS2_k127_501191_5 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 286.0
TLS2_k127_501191_6 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006764 272.0
TLS2_k127_501191_7 macromolecule localization K01992,K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000001092 244.0
TLS2_k127_501191_8 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000635 244.0
TLS2_k127_501191_9 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000006659 145.0
TLS2_k127_5024350_0 PQQ-like domain K17760 - 1.1.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 413.0
TLS2_k127_5024350_1 Mn2 and Fe2 transporters of the NRAMP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001051 266.0
TLS2_k127_5046319_0 transcription factor binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 563.0
TLS2_k127_5046319_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 530.0
TLS2_k127_5046319_2 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 528.0
TLS2_k127_5046319_3 epimerase K00486 - 1.14.13.9 0.0000000000000000000000000000000000000000000265 168.0
TLS2_k127_5046319_4 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000003612 88.0
TLS2_k127_50492_0 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008183 271.0
TLS2_k127_50492_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000005561 206.0
TLS2_k127_50492_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000001067 109.0
TLS2_k127_5050007_0 TonB-dependent receptor - - - 8.796e-195 638.0
TLS2_k127_5050007_1 Trehalose utilisation - - - 0.000000000000001537 80.0
TLS2_k127_5052677_0 Conserved carboxylase domain K01958 - 6.4.1.1 1.279e-250 781.0
TLS2_k127_5071833_0 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 607.0
TLS2_k127_5071833_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05565 - - 0.000000000000000000000000000000000000000000000000000462 191.0
TLS2_k127_5071833_2 Na+/H+ ion antiporter subunit K05569 - - 0.00000000000000000000000000000000000000001889 174.0
TLS2_k127_5071833_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560,K05567 - - 0.000000000000000000000000000000000002914 148.0
TLS2_k127_5071833_4 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.000000000000000000000000000000003264 141.0
TLS2_k127_5071833_5 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000007941 117.0
TLS2_k127_5071833_6 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.0000000000004216 79.0
TLS2_k127_5086567_0 Domain of unknown function (DUF5060) - - - 8.355e-212 696.0
TLS2_k127_5086567_1 neurotransmitter:sodium symporter activity K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 548.0
TLS2_k127_5086567_2 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 369.0
TLS2_k127_5086567_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000004604 222.0
TLS2_k127_5086567_4 Ion transport protein K08714 - - 0.0001546 46.0
TLS2_k127_5086567_5 Beta-lactamase - - - 0.000166 55.0
TLS2_k127_5086913_0 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005998 302.0
TLS2_k127_5086913_1 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000005483 181.0
TLS2_k127_5101906_0 Peptidase family M3 K01284 - 3.4.15.5 3.89e-287 898.0
TLS2_k127_5101906_1 COG4772 Outer membrane receptor for Fe3 -dicitrate K16091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 621.0
TLS2_k127_5101906_10 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 315.0
TLS2_k127_5101906_11 AAA domain - - - 0.00000000000000000000000000000000000004199 152.0
TLS2_k127_5101906_12 DinB superfamily - - - 0.0000000000000003845 86.0
TLS2_k127_5101906_2 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 440.0
TLS2_k127_5101906_3 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 410.0
TLS2_k127_5101906_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 389.0
TLS2_k127_5101906_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 351.0
TLS2_k127_5101906_6 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 339.0
TLS2_k127_5101906_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 324.0
TLS2_k127_5101906_8 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 326.0
TLS2_k127_5101906_9 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 325.0
TLS2_k127_510694_0 Peptidase family M1 domain K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 324.0
TLS2_k127_5109300_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 567.0
TLS2_k127_5109300_1 alcohol dehydrogenase K00043 - 1.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 508.0
TLS2_k127_5109300_10 COG0530 Ca2 Na antiporter K07301 - - 0.000000000000000000000000003958 127.0
TLS2_k127_5109300_11 Methyltransferase FkbM domain - - - 0.0000000000000000005039 95.0
TLS2_k127_5109300_12 - - - - 0.000000000000000001471 90.0
TLS2_k127_5109300_13 RNA recognition motif - - - 0.0000000000000003718 87.0
TLS2_k127_5109300_14 - - - - 0.0000000000009139 81.0
TLS2_k127_5109300_15 Polymer-forming cytoskeletal - - - 0.00000000004339 70.0
TLS2_k127_5109300_16 - - - - 0.0000000007601 66.0
TLS2_k127_5109300_17 Natural resistance-associated macrophage protein - - - 0.000000002796 65.0
TLS2_k127_5109300_18 Endonuclease Exonuclease Phosphatase - - - 0.000408 52.0
TLS2_k127_5109300_2 Fe-S oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 354.0
TLS2_k127_5109300_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 326.0
TLS2_k127_5109300_4 ABC transporter K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001548 273.0
TLS2_k127_5109300_5 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000002967 267.0
TLS2_k127_5109300_6 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000001441 183.0
TLS2_k127_5109300_7 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000002619 149.0
TLS2_k127_5109300_8 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000001366 145.0
TLS2_k127_5109300_9 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000000000000000000000001886 149.0
TLS2_k127_5143526_0 Transglutaminase-like - - - 0.0000000000000000000000000000000000000000000000000000000000002121 226.0
TLS2_k127_5169308_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006842 286.0
TLS2_k127_5169308_1 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000001135 212.0
TLS2_k127_5169308_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03086,K03093 - - 0.0009522 42.0
TLS2_k127_5171884_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 571.0
TLS2_k127_5171884_1 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 497.0
TLS2_k127_5171884_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000005036 192.0
TLS2_k127_5171884_11 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000003571 194.0
TLS2_k127_5171884_12 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000003358 182.0
TLS2_k127_5171884_13 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000007041 187.0
TLS2_k127_5171884_14 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000001236 178.0
TLS2_k127_5171884_15 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.000000000000000000000000001477 119.0
TLS2_k127_5171884_2 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 426.0
TLS2_k127_5171884_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 379.0
TLS2_k127_5171884_4 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 286.0
TLS2_k127_5171884_5 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001267 272.0
TLS2_k127_5171884_6 Squalene/phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002161 256.0
TLS2_k127_5171884_7 Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000359 216.0
TLS2_k127_5171884_8 TIGRFAM squalene-associated FAD-dependent desaturase - - - 0.000000000000000000000000000000000000000000000000000003208 213.0
TLS2_k127_5171884_9 GDP-mannose mannosyl hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000003678 194.0
TLS2_k127_5173723_0 Sodium:solute symporter family - - - 2.014e-259 812.0
TLS2_k127_5173723_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000002404 230.0
TLS2_k127_5173723_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000143 195.0
TLS2_k127_5173723_3 Galactokinase galactose-binding signature - - - 0.000000000000235 79.0
TLS2_k127_5185645_0 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 515.0
TLS2_k127_5185645_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000004584 131.0
TLS2_k127_5185645_2 - - - - 0.000000000000000000000000000001862 136.0
TLS2_k127_5185645_3 Periplasmic sensor domain K13069,K21085 - 2.7.7.65 0.00000000000000006341 92.0
TLS2_k127_5185645_4 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000000004832 71.0
TLS2_k127_5185645_5 - - - - 0.000000000005084 78.0
TLS2_k127_5190115_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.647e-196 627.0
TLS2_k127_5190115_1 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 449.0
TLS2_k127_5190115_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 411.0
TLS2_k127_5190115_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 406.0
TLS2_k127_5190115_4 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 376.0
TLS2_k127_5192652_0 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 347.0
TLS2_k127_5192652_1 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000004253 166.0
TLS2_k127_5199023_0 Peptidase family M28 - - - 4.69e-204 649.0
TLS2_k127_5199023_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 320.0
TLS2_k127_5199023_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000003096 243.0
TLS2_k127_5199023_3 Methylmalonyl-CoA mutase K01847,K03763,K14447 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944 2.7.7.7,5.4.99.2,5.4.99.63 0.0000000000000000000000000000000000000000000000007009 188.0
TLS2_k127_5199023_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000003772 77.0
TLS2_k127_5199023_5 Biotin-requiring enzyme K17490 - 2.1.3.1 0.0000000002886 63.0
TLS2_k127_5210541_0 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 406.0
TLS2_k127_5210541_2 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0000000000000000000000000000000000116 153.0
TLS2_k127_5210541_3 N-acetylmuramoyl-L-alanine amidase K01446 - - 0.00000000000000000008632 103.0
TLS2_k127_5210541_4 SnoaL-like domain - - - 0.0000000000003316 71.0
TLS2_k127_5210541_5 COG3209 Rhs family protein - - - 0.0000003603 59.0
TLS2_k127_5215274_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 402.0
TLS2_k127_5215274_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 392.0
TLS2_k127_5215274_2 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00003161 49.0
TLS2_k127_5215522_0 COGs COG4299 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 500.0
TLS2_k127_5215522_1 OsmC-like protein K04063 - - 0.00000000000000000000000000005136 121.0
TLS2_k127_5215522_2 Lysylphosphatidylglycerol synthase TM region - - - 0.000002548 59.0
TLS2_k127_5215522_3 Domain of unknown function (DUF4203) - - - 0.0007534 50.0
TLS2_k127_5226325_0 secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 554.0
TLS2_k127_5226325_1 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 316.0
TLS2_k127_5226325_10 Flp Fap pilin component - - - 0.00005272 48.0
TLS2_k127_5226325_11 Flp Fap pilin component K02651 - - 0.0004795 46.0
TLS2_k127_5226325_2 type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000004992 219.0
TLS2_k127_5226325_3 ATPase with chaperone activity - - - 0.0000000000000000000000000000000000000000000000000000000009017 222.0
TLS2_k127_5226325_4 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000000000008916 208.0
TLS2_k127_5226325_5 PFAM SAF domain K02279 - - 0.000000000000000000000000000000000000000000001927 175.0
TLS2_k127_5226325_6 AAA domain K02282 - - 0.0000000000000000000000000000000000000006997 163.0
TLS2_k127_5226325_7 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000001087 154.0
TLS2_k127_5226325_8 PFAM Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.0000000000000000006648 93.0
TLS2_k127_5226325_9 TadE-like protein - - - 0.000001584 57.0
TLS2_k127_5231821_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 608.0
TLS2_k127_5231821_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000002488 218.0
TLS2_k127_5271826_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 9.007e-230 720.0
TLS2_k127_5271826_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 612.0
TLS2_k127_5271826_10 Type II secretion system protein G K02456 - - 0.00000000000009133 72.0
TLS2_k127_5271826_11 CAAX protease self-immunity K07052 - - 0.00000000002543 76.0
TLS2_k127_5271826_12 Protein of unknown function (DUF1360) - - - 0.00001335 55.0
TLS2_k127_5271826_2 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 554.0
TLS2_k127_5271826_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 501.0
TLS2_k127_5271826_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 470.0
TLS2_k127_5271826_5 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 414.0
TLS2_k127_5271826_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 375.0
TLS2_k127_5271826_7 Aldolase/RraA K10218 - 4.1.3.17 0.000000000000000000000000000000000000000000000000000000000000000000001846 244.0
TLS2_k127_5271826_8 PFAM Cytochrome C - - - 0.000000000000000001043 94.0
TLS2_k127_5271826_9 Histidine kinase - - - 0.00000000000001568 80.0
TLS2_k127_5286137_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 464.0
TLS2_k127_5286137_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002462 275.0
TLS2_k127_5286137_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003411 268.0
TLS2_k127_5286137_3 Transcriptional regulator - - - 0.00000000000000000000000000008377 120.0
TLS2_k127_5286137_4 Trypsin K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.000000000001375 80.0
TLS2_k127_5286137_5 NhaP-type Na H and K H - - - 0.000000004538 68.0
TLS2_k127_531445_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 2167.0
TLS2_k127_5316802_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 357.0
TLS2_k127_5316802_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000004653 143.0
TLS2_k127_532364_0 Prolyl oligopeptidase family - - - 3.762e-271 855.0
TLS2_k127_532364_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 580.0
TLS2_k127_532364_10 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.000000000000000000000000000000000000000000007257 170.0
TLS2_k127_532364_11 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000003569 167.0
TLS2_k127_532364_12 - - - - 0.000000000000000000000000000000000003062 154.0
TLS2_k127_532364_13 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000004395 132.0
TLS2_k127_532364_14 membrane - - - 0.0000000000000000000004928 111.0
TLS2_k127_532364_15 CAAX protease self-immunity K07052 - - 0.000000000000000002539 95.0
TLS2_k127_532364_16 Alpha beta hydrolase - - - 0.000000000316 70.0
TLS2_k127_532364_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 458.0
TLS2_k127_532364_3 PFAM amine oxidase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 358.0
TLS2_k127_532364_4 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 338.0
TLS2_k127_532364_5 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 309.0
TLS2_k127_532364_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 317.0
TLS2_k127_532364_7 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000568 229.0
TLS2_k127_532364_8 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000004487 222.0
TLS2_k127_532364_9 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000003223 207.0
TLS2_k127_5366564_0 Radical SAM - - - 0.0 1131.0
TLS2_k127_5366564_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 441.0
TLS2_k127_5366564_10 NfeD-like C-terminal, partner-binding K07403 - - 0.0000005218 58.0
TLS2_k127_5366564_11 - - - - 0.00000389 57.0
TLS2_k127_5366564_2 Oxidoreductase molybdopterin binding domain K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 417.0
TLS2_k127_5366564_3 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 351.0
TLS2_k127_5366564_4 SMART ATPase, AAA type, core K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003995 267.0
TLS2_k127_5366564_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000005774 199.0
TLS2_k127_5366564_6 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.000000000000000000000000000000000000000000000000000002833 209.0
TLS2_k127_5366564_7 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000008171 179.0
TLS2_k127_5366564_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000003089 84.0
TLS2_k127_5366564_9 Polysaccharide deacetylase - - - 0.0000000000001737 79.0
TLS2_k127_5371307_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000051 180.0
TLS2_k127_5371307_1 Heavy-metal resistance - - - 0.0000003882 60.0
TLS2_k127_5371307_2 PFAM outer membrane efflux protein - - - 0.0001428 50.0
TLS2_k127_5378857_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.059e-284 914.0
TLS2_k127_5378857_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 460.0
TLS2_k127_5378857_2 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 461.0
TLS2_k127_5378857_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002388 285.0
TLS2_k127_5378857_4 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001236 265.0
TLS2_k127_5378857_5 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000002813 205.0
TLS2_k127_5378857_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000004368 187.0
TLS2_k127_5378857_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000008425 123.0
TLS2_k127_5378857_8 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000001638 131.0
TLS2_k127_5380218_0 Alpha-L-rhamnosidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 328.0
TLS2_k127_5380218_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000261 212.0
TLS2_k127_5380218_2 Cysteine-rich secretory protein family - - - 0.000000000000000000000001457 113.0
TLS2_k127_5405278_0 DinB family - - - 0.0000000000000000000004941 98.0
TLS2_k127_5405278_1 oxidoreductase activity - - - 0.00004431 56.0
TLS2_k127_5420077_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 480.0
TLS2_k127_5420077_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 458.0
TLS2_k127_5420077_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000001418 139.0
TLS2_k127_5420077_11 ABC transporter permease K02033 - - 0.00000000000001348 74.0
TLS2_k127_5420077_12 SMART RNA-processing protein HAT helix repeating-containing protein - - - 0.00000001502 67.0
TLS2_k127_5420077_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 409.0
TLS2_k127_5420077_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 358.0
TLS2_k127_5420077_4 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 330.0
TLS2_k127_5420077_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 301.0
TLS2_k127_5420077_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000002474 272.0
TLS2_k127_5420077_7 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000004156 253.0
TLS2_k127_5420077_8 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000007809 207.0
TLS2_k127_5420077_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000003399 188.0
TLS2_k127_5421081_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 325.0
TLS2_k127_5421081_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008527 271.0
TLS2_k127_5421081_2 COGs COG5616 integral membrane protein - - - 0.000000000000000000000000000000000000000000007233 188.0
TLS2_k127_5427650_0 alpha beta - - - 4.653e-200 656.0
TLS2_k127_5427650_1 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 433.0
TLS2_k127_5427650_2 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 395.0
TLS2_k127_5427650_3 myo-inosose-2 dehydratase activity - - - 0.00000000001109 74.0
TLS2_k127_5447994_0 Protein of unknown function (DUF1553) - - - 0.0 1030.0
TLS2_k127_5447994_1 Protein of unknown function (DUF1501) - - - 1.699e-225 707.0
TLS2_k127_5447994_10 O-linked N-acetylglucosamine transferase - - - 0.000000008349 68.0
TLS2_k127_5447994_2 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 428.0
TLS2_k127_5447994_3 Vitamin K epoxide reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 411.0
TLS2_k127_5447994_4 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 351.0
TLS2_k127_5447994_5 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 335.0
TLS2_k127_5447994_6 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 331.0
TLS2_k127_5447994_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000483 240.0
TLS2_k127_5447994_8 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000003393 126.0
TLS2_k127_5447994_9 Tetratricopeptide repeat - - - 0.0000000000000000002003 103.0
TLS2_k127_5464848_0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 329.0
TLS2_k127_5464848_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000001616 190.0
TLS2_k127_5464848_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000006005 151.0
TLS2_k127_5464848_3 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000001969 140.0
TLS2_k127_5465517_0 efflux transmembrane transporter activity - - - 9.613e-236 754.0
TLS2_k127_5465517_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - - 0.000000000000000000000000000000000000002926 147.0
TLS2_k127_5470467_0 C-terminal domain of CHU protein family K20276 - - 0.0000000000000000000000000000000008197 149.0
TLS2_k127_5531082_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 511.0
TLS2_k127_5531082_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 453.0
TLS2_k127_5531082_2 Replicative DNA helicase K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 423.0
TLS2_k127_5531082_3 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 379.0
TLS2_k127_5531082_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 332.0
TLS2_k127_5531082_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000237 281.0
TLS2_k127_5531082_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000009956 209.0
TLS2_k127_5531082_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000002186 179.0
TLS2_k127_5533475_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1125.0
TLS2_k127_5533475_1 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 318.0
TLS2_k127_5533475_2 Peptidase family M41 K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 292.0
TLS2_k127_5534403_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1214.0
TLS2_k127_5534403_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 479.0
TLS2_k127_5534403_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 419.0
TLS2_k127_5534403_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 403.0
TLS2_k127_5534403_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000005731 233.0
TLS2_k127_5534403_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000001051 147.0
TLS2_k127_5534403_6 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000004894 130.0
TLS2_k127_5534403_7 Protein of unknown function (DUF4242) - - - 0.000000000000000000000002078 106.0
TLS2_k127_5534403_8 G8 - - - 0.00000000000000000000001126 117.0
TLS2_k127_5534812_0 pyrroloquinoline quinone binding - - - 9.18e-225 727.0
TLS2_k127_5534812_1 Pfam 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000001842 199.0
TLS2_k127_5566312_0 pyrroloquinoline quinone binding - - - 1.419e-238 765.0
TLS2_k127_5566312_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.246e-216 681.0
TLS2_k127_5566312_2 PFAM Glucuronate isomerase K01812 - 5.3.1.12 7.495e-213 672.0
TLS2_k127_5566312_3 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 438.0
TLS2_k127_5566312_4 BNR repeat-like domain K05989 - 3.2.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 404.0
TLS2_k127_5566312_5 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 308.0
TLS2_k127_5566312_6 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003492 277.0
TLS2_k127_5566312_7 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000004425 180.0
TLS2_k127_5566312_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000132 146.0
TLS2_k127_5570923_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 1.3e-276 866.0
TLS2_k127_5570923_1 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 635.0
TLS2_k127_5570923_10 COG0073 EMAP domain K06878 - - 0.000000000000000000000000000000000000000000004354 168.0
TLS2_k127_5570923_11 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000637 162.0
TLS2_k127_5570923_12 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000003782 173.0
TLS2_k127_5570923_13 Chorismate mutase type II K04093 - 5.4.99.5 0.0000000000000000003453 93.0
TLS2_k127_5570923_14 JAB/MPN domain - - - 0.000000000000000005331 91.0
TLS2_k127_5570923_2 PQQ-like domain K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 619.0
TLS2_k127_5570923_3 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 578.0
TLS2_k127_5570923_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 542.0
TLS2_k127_5570923_5 PhoPQ-activated pathogenicity-related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 513.0
TLS2_k127_5570923_6 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 494.0
TLS2_k127_5570923_7 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 421.0
TLS2_k127_5570923_8 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 306.0
TLS2_k127_5570923_9 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000002653 236.0
TLS2_k127_560283_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 1.537e-241 758.0
TLS2_k127_560283_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 570.0
TLS2_k127_560283_11 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.0000000000000000000000001779 107.0
TLS2_k127_560283_12 Domain of unknown function (DUF4154) - - - 0.00000000000000000001547 106.0
TLS2_k127_560283_13 Surface antigen - - - 0.000000000000005485 88.0
TLS2_k127_560283_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.000006619 55.0
TLS2_k127_560283_15 aminopeptidase N - - - 0.0003436 51.0
TLS2_k127_560283_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 473.0
TLS2_k127_560283_3 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 397.0
TLS2_k127_560283_4 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 354.0
TLS2_k127_560283_5 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 326.0
TLS2_k127_560283_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008688 303.0
TLS2_k127_560283_7 Uncharacterized conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001814 273.0
TLS2_k127_560283_8 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000001772 235.0
TLS2_k127_560283_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000004467 193.0
TLS2_k127_561243_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 567.0
TLS2_k127_561243_1 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000001432 166.0
TLS2_k127_5615019_0 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 467.0
TLS2_k127_5615019_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 401.0
TLS2_k127_5615019_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 350.0
TLS2_k127_5615019_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008691 301.0
TLS2_k127_5615019_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000006341 207.0
TLS2_k127_5615019_5 Glycosyl transferases group 1 - - - 0.000000000000000807 79.0
TLS2_k127_5617727_0 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 629.0
TLS2_k127_5617727_1 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 342.0
TLS2_k127_5617727_10 Cupin domain - - - 0.00000000000000000000000000001584 125.0
TLS2_k127_5617727_11 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000003549 119.0
TLS2_k127_5617727_12 ribonuclease activity - - - 0.00000000000000000000000006511 118.0
TLS2_k127_5617727_13 - - - - 0.0000000000000000000000006636 108.0
TLS2_k127_5617727_14 lactoylglutathione lyase activity - - - 0.00000000000000000000003599 101.0
TLS2_k127_5617727_15 - - - - 0.0000000000000000000005919 110.0
TLS2_k127_5617727_16 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000001422 84.0
TLS2_k127_5617727_18 Protein of unknown function DUF86 - - - 0.000000000125 68.0
TLS2_k127_5617727_19 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000001486 65.0
TLS2_k127_5617727_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006733 275.0
TLS2_k127_5617727_20 Domain of unknown function (DUF4143) - - - 0.0000000001942 68.0
TLS2_k127_5617727_21 Nucleotidyltransferase domain - - - 0.00000001875 61.0
TLS2_k127_5617727_22 oxidoreductase activity - - - 0.0000009235 62.0
TLS2_k127_5617727_23 ATPase (AAA superfamily K07133 - - 0.0000237 54.0
TLS2_k127_5617727_24 oxidoreductase activity - - - 0.00003892 55.0
TLS2_k127_5617727_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000005584 228.0
TLS2_k127_5617727_4 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000007607 201.0
TLS2_k127_5617727_5 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000009225 193.0
TLS2_k127_5617727_6 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000128 192.0
TLS2_k127_5617727_7 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000004746 186.0
TLS2_k127_5617727_8 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000005307 156.0
TLS2_k127_5617727_9 acetyltransferase K00950,K03789,K03823 - 2.3.1.128,2.3.1.183,2.7.6.3 0.000000000000000000000000000000001979 140.0
TLS2_k127_5623649_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1782.0
TLS2_k127_5623649_1 E1-E2 ATPase - - - 1.617e-291 913.0
TLS2_k127_5623649_10 Transcriptional regulator, BadM Rrf2 family - - - 0.000000000000000000000000000123 120.0
TLS2_k127_5623649_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000004339 126.0
TLS2_k127_5623649_12 - - - - 0.000000000000000000000000001974 124.0
TLS2_k127_5623649_13 cheY-homologous receiver domain - - - 0.000000000000000000002699 100.0
TLS2_k127_5623649_14 chaperone-mediated protein complex assembly - - - 0.0000000000000000001131 103.0
TLS2_k127_5623649_2 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 3.667e-199 625.0
TLS2_k127_5623649_3 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 587.0
TLS2_k127_5623649_4 Nucleoside H+ symporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 470.0
TLS2_k127_5623649_5 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000037 267.0
TLS2_k127_5623649_6 nitrate reductase molybdenum cofactor assembly chaperone K17052 - - 0.000000000000000000000000000000000000000000000000000000000000000001744 238.0
TLS2_k127_5623649_7 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000007911 227.0
TLS2_k127_5623649_8 methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000005329 219.0
TLS2_k127_5623649_9 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000004806 206.0
TLS2_k127_5628491_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 561.0
TLS2_k127_5628491_1 TrkA-C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007256 481.0
TLS2_k127_5628491_10 GDP-mannose 4,6 dehydratase K19180 - 1.1.1.339 0.0000000000000000000000000000000000000001924 162.0
TLS2_k127_5628491_11 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000002113 151.0
TLS2_k127_5628491_12 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000006763 108.0
TLS2_k127_5628491_13 MobA-related protein K07141 - 2.7.7.76 0.000000000000000000009871 101.0
TLS2_k127_5628491_14 Cold shock protein domain - - - 0.000000000001088 70.0
TLS2_k127_5628491_2 PFAM NAD dependent epimerase dehydratase family K01709,K01710,K01784 - 4.2.1.45,4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 399.0
TLS2_k127_5628491_3 PFAM sodium calcium exchanger K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 365.0
TLS2_k127_5628491_4 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 345.0
TLS2_k127_5628491_5 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 346.0
TLS2_k127_5628491_6 Putative zinc binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 337.0
TLS2_k127_5628491_7 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006624 274.0
TLS2_k127_5628491_8 Polycystin cation channel K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001104 267.0
TLS2_k127_5628491_9 Evidence 4 Homologs of previously reported genes of K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009708 257.0
TLS2_k127_5640318_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.201e-292 915.0
TLS2_k127_5640318_1 Response regulator receiver - - - 3.64e-205 650.0
TLS2_k127_5640318_10 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000002239 234.0
TLS2_k127_5640318_11 uracil phosphoribosyltransferase K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000001294 216.0
TLS2_k127_5640318_12 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000001885 204.0
TLS2_k127_5640318_13 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000001415 201.0
TLS2_k127_5640318_15 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000001634 126.0
TLS2_k127_5640318_16 von Willebrand factor, type A - - - 0.00000000000000000000000004998 119.0
TLS2_k127_5640318_17 Organic solvent ABC transporter substrate-binding protein K02067 - - 0.0000000000000006987 89.0
TLS2_k127_5640318_18 YtxH-like protein - - - 0.000009527 51.0
TLS2_k127_5640318_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 548.0
TLS2_k127_5640318_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 435.0
TLS2_k127_5640318_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 370.0
TLS2_k127_5640318_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 315.0
TLS2_k127_5640318_6 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001691 285.0
TLS2_k127_5640318_7 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000007063 258.0
TLS2_k127_5640318_8 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009135 247.0
TLS2_k127_5640318_9 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000001141 245.0
TLS2_k127_564185_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 534.0
TLS2_k127_564185_1 - - - - 0.00000000000000003234 83.0
TLS2_k127_5655639_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 402.0
TLS2_k127_5655639_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 288.0
TLS2_k127_5666403_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004414 250.0
TLS2_k127_5666403_1 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.000000000001173 72.0
TLS2_k127_5666403_2 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000003248 52.0
TLS2_k127_5684770_0 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000001359 217.0
TLS2_k127_5684770_1 Ferric uptake regulator family K09825 - - 0.00000000000000000000000000000000000000000013 165.0
TLS2_k127_5684770_2 Disulfide bond formation protein DsbB K03611 - - 0.000000000000000000000000000000000000000003819 159.0
TLS2_k127_5684770_3 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.000000000000000000001914 96.0
TLS2_k127_5684770_4 manually curated - - - 0.00000005565 55.0
TLS2_k127_5691089_0 Surface antigen K07277 - - 0.000000000000000000000000000000005099 134.0
TLS2_k127_5691089_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000003502 70.0
TLS2_k127_5699533_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.357e-306 954.0
TLS2_k127_5699533_1 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 510.0
TLS2_k127_5699533_2 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 310.0
TLS2_k127_5699533_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001459 246.0
TLS2_k127_5699533_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000008321 164.0
TLS2_k127_5699533_5 PFAM Methyltransferase type 11 - - - 0.0000000000002588 81.0
TLS2_k127_5699533_6 PFAM Abortive infection protein K07052 - - 0.00009597 53.0
TLS2_k127_5706878_0 Protein of unknown function (DUF1553) - - - 1.56e-297 933.0
TLS2_k127_5706878_1 Protein of unknown function (DUF1501) - - - 5.23e-233 729.0
TLS2_k127_5706878_10 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000004249 114.0
TLS2_k127_5706878_11 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000003081 111.0
TLS2_k127_5706878_12 peptidyl-tyrosine sulfation - - - 0.0000000000000000004992 102.0
TLS2_k127_5706878_13 - - - - 0.00000001457 59.0
TLS2_k127_5706878_14 Carboxypeptidase regulatory-like domain - - - 0.00000114 54.0
TLS2_k127_5706878_2 ASPIC and UnbV - - - 6.13e-231 728.0
TLS2_k127_5706878_3 AMP-binding enzyme C-terminal domain K18661 - - 1.514e-198 630.0
TLS2_k127_5706878_4 L-lactate dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 489.0
TLS2_k127_5706878_5 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 452.0
TLS2_k127_5706878_6 Periplasmic binding proteins and sugar binding domain of LacI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 432.0
TLS2_k127_5706878_7 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 421.0
TLS2_k127_5706878_8 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 341.0
TLS2_k127_5706878_9 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 330.0
TLS2_k127_5708130_0 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000001964 196.0
TLS2_k127_5708130_1 Outer membrane protein beta-barrel family - - - 0.000000000000000000000000000000000000000000000005853 190.0
TLS2_k127_5708130_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000005056 85.0
TLS2_k127_5711341_0 Drug exporters of the RND superfamily K06994,K07003 - - 4.179e-208 670.0
TLS2_k127_5711341_1 nuclear-transcribed mRNA catabolic process, no-go decay - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 527.0
TLS2_k127_5711341_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000003768 109.0
TLS2_k127_5711341_11 - - - - 0.000000000000000002103 96.0
TLS2_k127_5711341_13 Bacterial regulatory proteins, tetR family - - - 0.00000003565 57.0
TLS2_k127_5711341_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 447.0
TLS2_k127_5711341_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 413.0
TLS2_k127_5711341_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 388.0
TLS2_k127_5711341_5 sigma factor antagonist activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 346.0
TLS2_k127_5711341_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000002212 175.0
TLS2_k127_5711341_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000192 178.0
TLS2_k127_5711341_8 - - - - 0.00000000000000000000000000000008603 128.0
TLS2_k127_5711341_9 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000008767 115.0
TLS2_k127_5717660_0 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000000007124 66.0
TLS2_k127_5717660_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0004972 46.0
TLS2_k127_5723678_0 Belongs to the UbiD family K03182 - 4.1.1.98 8.511e-299 929.0
TLS2_k127_5723678_1 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 481.0
TLS2_k127_5723678_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009 275.0
TLS2_k127_5723678_11 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000001846 244.0
TLS2_k127_5723678_12 dehydratase - - - 0.00000000000000000000000000000000000000000000000000001556 194.0
TLS2_k127_5723678_13 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000008917 205.0
TLS2_k127_5723678_14 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000002305 191.0
TLS2_k127_5723678_15 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000001012 184.0
TLS2_k127_5723678_16 Methyltransferase type 11 - - - 0.0000000000000000000000000000006822 134.0
TLS2_k127_5723678_17 DinB family - - - 0.00000000000000000000000000001596 123.0
TLS2_k127_5723678_18 Tetratricopeptide repeat - - - 0.00000000000000000000002979 115.0
TLS2_k127_5723678_19 Protein of unknown function (DUF3137) - - - 0.0000000000000000001326 102.0
TLS2_k127_5723678_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 487.0
TLS2_k127_5723678_20 PAP2 superfamily - - - 0.00000000000000002386 92.0
TLS2_k127_5723678_22 Rhodanese Homology Domain - - - 0.0000000000137 76.0
TLS2_k127_5723678_3 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 466.0
TLS2_k127_5723678_4 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 410.0
TLS2_k127_5723678_5 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 314.0
TLS2_k127_5723678_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 325.0
TLS2_k127_5723678_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001306 286.0
TLS2_k127_5723678_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007217 274.0
TLS2_k127_5723678_9 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001295 270.0
TLS2_k127_5727772_0 cell redox homeostasis - - - 8.756e-242 758.0
TLS2_k127_5727772_1 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 377.0
TLS2_k127_5727772_2 regulation of translation K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000004646 115.0
TLS2_k127_5727772_3 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000006285 93.0
TLS2_k127_5743090_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 499.0
TLS2_k127_5743090_1 Belongs to the glycosyl hydrolase 13 family K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 313.0
TLS2_k127_5743090_2 - - - - 0.00000000000000000000000000000000000000000000002497 180.0
TLS2_k127_5758213_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 4.932e-277 867.0
TLS2_k127_5758213_1 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 469.0
TLS2_k127_5758213_2 trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 454.0
TLS2_k127_5758213_3 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002747 271.0
TLS2_k127_5758213_4 cobalamin binding K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000002867 256.0
TLS2_k127_5758213_5 Putative transposase - - - 0.00000000000000000000006336 105.0
TLS2_k127_5758213_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000005947 91.0
TLS2_k127_5774528_0 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 552.0
TLS2_k127_5781624_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 574.0
TLS2_k127_5781624_1 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 491.0
TLS2_k127_5781624_10 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000007343 202.0
TLS2_k127_5781624_11 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000009888 183.0
TLS2_k127_5781624_12 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000004303 188.0
TLS2_k127_5781624_13 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000101 156.0
TLS2_k127_5781624_14 - - - - 0.000000000000001188 87.0
TLS2_k127_5781624_15 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000002332 85.0
TLS2_k127_5781624_19 Bacterial antitoxin of type II TA system, VapB - - - 0.000007511 51.0
TLS2_k127_5781624_2 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 330.0
TLS2_k127_5781624_20 Concanavalin A-like lectin/glucanases superfamily - - - 0.00001415 57.0
TLS2_k127_5781624_21 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0001648 50.0
TLS2_k127_5781624_3 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 293.0
TLS2_k127_5781624_4 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001052 274.0
TLS2_k127_5781624_5 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000008121 274.0
TLS2_k127_5781624_6 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001674 254.0
TLS2_k127_5781624_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000004405 241.0
TLS2_k127_5781624_9 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000005709 219.0
TLS2_k127_5785875_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 411.0
TLS2_k127_5785875_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 397.0
TLS2_k127_5785875_2 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 298.0
TLS2_k127_5785875_3 Phosphogluconate dehydrogenase (decarboxylating) C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002107 286.0
TLS2_k127_5785875_4 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000369 266.0
TLS2_k127_5785875_5 Branched-chain amino acid transport system / permease component K02057,K10440 - - 0.0000000000000005607 92.0
TLS2_k127_5785875_6 - - - - 0.0000000229 60.0
TLS2_k127_5786933_0 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 432.0
TLS2_k127_5786933_1 GYD domain - - - 0.000000000000007783 78.0
TLS2_k127_5786933_2 - - - - 0.000000003662 60.0
TLS2_k127_5786933_3 PIN domain K07064 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.0009133 46.0
TLS2_k127_5787979_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239,K00244,K00278 GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 1.3.5.1,1.3.5.4,1.4.3.16 9.68e-296 915.0
TLS2_k127_5787979_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 6.181e-270 840.0
TLS2_k127_5787979_10 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001325 280.0
TLS2_k127_5787979_11 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007311 274.0
TLS2_k127_5787979_12 Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002494 253.0
TLS2_k127_5787979_13 Alkaline phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002906 252.0
TLS2_k127_5787979_14 - - - - 0.0000000000000000000000000000000000000000000000000000000001164 214.0
TLS2_k127_5787979_15 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000001365 165.0
TLS2_k127_5787979_16 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 - - 0.0000000000000000000000000000000000003296 145.0
TLS2_k127_5787979_17 PFAM small multidrug resistance protein K11741 - - 0.000000000000000000000000000000000002957 140.0
TLS2_k127_5787979_18 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000001052 141.0
TLS2_k127_5787979_19 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00246 - - 0.000000000000000000000000000000001074 139.0
TLS2_k127_5787979_2 O-acetylhomoserine K01740 - 2.5.1.49 5.367e-249 774.0
TLS2_k127_5787979_20 - - - - 0.00000000000000009077 83.0
TLS2_k127_5787979_21 ANTAR K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.00000000000002925 81.0
TLS2_k127_5787979_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 3.229e-214 671.0
TLS2_k127_5787979_4 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 1.295e-202 647.0
TLS2_k127_5787979_5 Succinate dehydrogenase fumarate reductase K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 396.0
TLS2_k127_5787979_6 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 395.0
TLS2_k127_5787979_7 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 376.0
TLS2_k127_5787979_8 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 372.0
TLS2_k127_5787979_9 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 327.0
TLS2_k127_5789457_0 NADH ubiquinone oxidoreductase, 20 K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 554.0
TLS2_k127_5789457_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 433.0
TLS2_k127_5789457_2 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 332.0
TLS2_k127_5789457_3 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004571 293.0
TLS2_k127_5789457_5 PRC-barrel domain - - - 0.0000000000000001124 88.0
TLS2_k127_5792016_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 471.0
TLS2_k127_5819786_0 COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit K02470,K02622 - 5.99.1.3 5.827e-282 878.0
TLS2_k127_5819786_1 NAD(P)H quinone oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 401.0
TLS2_k127_5819786_2 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 316.0
TLS2_k127_5819786_3 eRF1 domain 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 316.0
TLS2_k127_5819786_4 FRG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 308.0
TLS2_k127_5819786_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002776 265.0
TLS2_k127_5819786_6 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000136 195.0
TLS2_k127_5819786_7 FAD dependent oxidoreductase - - - 0.000000000000000000000000001239 128.0
TLS2_k127_5819786_8 PFAM SNARE associated Golgi protein - - - 0.00000000002188 74.0
TLS2_k127_5819786_9 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0008002 42.0
TLS2_k127_5826258_0 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 607.0
TLS2_k127_5826258_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000005537 162.0
TLS2_k127_58408_0 MacB-like periplasmic core domain - - - 2.23e-303 951.0
TLS2_k127_58408_1 COG3119 Arylsulfatase A K01134 - 3.1.6.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 541.0
TLS2_k127_58408_2 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 534.0
TLS2_k127_58408_3 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 439.0
TLS2_k127_58408_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 389.0
TLS2_k127_58408_5 ATP dependent DNA ligase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 282.0
TLS2_k127_58408_6 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006346 256.0
TLS2_k127_5873196_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 1.202e-241 774.0
TLS2_k127_5873196_1 transport - - - 2.43e-234 764.0
TLS2_k127_5873196_10 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 317.0
TLS2_k127_5873196_11 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 294.0
TLS2_k127_5873196_12 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005863 282.0
TLS2_k127_5873196_13 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000099 253.0
TLS2_k127_5873196_14 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002011 234.0
TLS2_k127_5873196_15 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001656 216.0
TLS2_k127_5873196_16 - - - - 0.000000000000000000000000000000000000000000000002559 187.0
TLS2_k127_5873196_17 - - - - 0.00000000000000000000000000000000002594 146.0
TLS2_k127_5873196_18 ECF sigma factor - - - 0.0000000000000000000000000002108 118.0
TLS2_k127_5873196_19 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000002641 116.0
TLS2_k127_5873196_2 FtsX-like permease family - - - 6.765e-196 651.0
TLS2_k127_5873196_20 - - - - 0.000000000000000000000000003572 119.0
TLS2_k127_5873196_21 NADP Oxidoreductase K06988 - 1.5.1.40 0.000000000000000000000001437 105.0
TLS2_k127_5873196_24 TonB C terminal K03646 - - 0.00002436 52.0
TLS2_k127_5873196_25 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000124 51.0
TLS2_k127_5873196_3 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 522.0
TLS2_k127_5873196_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 459.0
TLS2_k127_5873196_5 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 440.0
TLS2_k127_5873196_6 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 419.0
TLS2_k127_5873196_7 Oxidoreductase molybdopterin binding domain K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 391.0
TLS2_k127_5873196_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 376.0
TLS2_k127_5873196_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 351.0
TLS2_k127_5874086_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 559.0
TLS2_k127_5874086_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 482.0
TLS2_k127_5874086_2 cell shape determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 462.0
TLS2_k127_5874086_3 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 325.0
TLS2_k127_5874086_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 290.0
TLS2_k127_5874086_5 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003341 287.0
TLS2_k127_5874086_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001104 273.0
TLS2_k127_5874086_7 WYL domain - - - 0.00000000000000000000000000000000000000000000001517 183.0
TLS2_k127_5874086_8 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000001408 101.0
TLS2_k127_5874086_9 - - - - 0.0000000000000000000001778 104.0
TLS2_k127_5891864_0 metallocarboxypeptidase activity K14054 - - 0.0 1053.0
TLS2_k127_5891864_1 ABC transporter K06020 - 3.6.3.25 2.116e-262 818.0
TLS2_k127_5891864_2 protein kinase activity K06915 - - 3.306e-252 802.0
TLS2_k127_5891864_3 Pfam:N_methyl_2 - - - 0.0001208 53.0
TLS2_k127_5895687_0 ABC transporter - - - 3.067e-275 854.0
TLS2_k127_5895687_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.184e-232 745.0
TLS2_k127_5895687_10 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 358.0
TLS2_k127_5895687_11 Histidine kinase K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 320.0
TLS2_k127_5895687_12 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 307.0
TLS2_k127_5895687_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 323.0
TLS2_k127_5895687_14 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 287.0
TLS2_k127_5895687_15 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001047 302.0
TLS2_k127_5895687_16 Converts the prephenate produced from the shikimate- chorismate pathway into phenylalanine K05359 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009314,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009637,GO:0009642,GO:0009645,GO:0009987,GO:0010244,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047769,GO:0050896,GO:0071704,GO:0080167,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51,4.2.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001311 283.0
TLS2_k127_5895687_17 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002652 282.0
TLS2_k127_5895687_18 Response regulator receiver K07705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000318 252.0
TLS2_k127_5895687_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001071 250.0
TLS2_k127_5895687_2 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 5.781e-213 679.0
TLS2_k127_5895687_20 methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000001505 192.0
TLS2_k127_5895687_21 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000002306 201.0
TLS2_k127_5895687_22 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000265 199.0
TLS2_k127_5895687_23 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000001245 186.0
TLS2_k127_5895687_24 domain, Protein - - - 0.00000000000000000000000000000000000000000000000002544 207.0
TLS2_k127_5895687_25 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000048 203.0
TLS2_k127_5895687_26 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000002494 183.0
TLS2_k127_5895687_27 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000945 183.0
TLS2_k127_5895687_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000002142 182.0
TLS2_k127_5895687_29 Glucose inhibited division protein A K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000005855 183.0
TLS2_k127_5895687_3 radical SAM domain protein - - - 1.096e-201 640.0
TLS2_k127_5895687_30 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000859 162.0
TLS2_k127_5895687_31 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000001807 156.0
TLS2_k127_5895687_32 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000009249 158.0
TLS2_k127_5895687_33 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX - - - 0.0000000000000000000000000000000000004174 160.0
TLS2_k127_5895687_34 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000008543 149.0
TLS2_k127_5895687_35 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000004554 143.0
TLS2_k127_5895687_36 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000000000006634 134.0
TLS2_k127_5895687_37 phosphoesterases, related to the Icc protein - - - 0.000000000000000000000000000002982 130.0
TLS2_k127_5895687_38 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000000000195 123.0
TLS2_k127_5895687_39 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.0000000000000000000000006442 110.0
TLS2_k127_5895687_4 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 629.0
TLS2_k127_5895687_40 PFAM Rhomboid family protein - - - 0.00000000000000000000003096 109.0
TLS2_k127_5895687_41 extracellular matrix structural constituent - - - 0.000000000000000003006 97.0
TLS2_k127_5895687_42 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity - - - 0.0000000000000000191 97.0
TLS2_k127_5895687_43 - - - - 0.000000005908 64.0
TLS2_k127_5895687_44 Uncharacterised nucleotidyltransferase - - - 0.0000000105 67.0
TLS2_k127_5895687_45 Ami_2 - - - 0.0000001179 63.0
TLS2_k127_5895687_48 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00008646 55.0
TLS2_k127_5895687_5 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 575.0
TLS2_k127_5895687_6 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 518.0
TLS2_k127_5895687_7 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 410.0
TLS2_k127_5895687_8 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 380.0
TLS2_k127_5895687_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 376.0
TLS2_k127_589619_0 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000000000008845 191.0
TLS2_k127_589619_1 - - - - 0.0000000000001586 79.0
TLS2_k127_589619_2 ADP-ribosyl-(Dinitrogen reductase) hydrolase K05521 - 3.2.2.24 0.00000000001037 68.0
TLS2_k127_5899469_0 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000005083 105.0
TLS2_k127_5907057_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 387.0
TLS2_k127_5907057_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000002031 243.0
TLS2_k127_5907057_2 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000002056 155.0
TLS2_k127_5907057_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000001317 144.0
TLS2_k127_5907057_4 thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000593 134.0
TLS2_k127_5907057_5 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000003914 131.0
TLS2_k127_5907057_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.00000000000000000000000003061 116.0
TLS2_k127_5907057_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000001257 90.0
TLS2_k127_5908623_0 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000001753 138.0
TLS2_k127_5908623_1 luxR family - - - 0.00004757 56.0
TLS2_k127_591577_0 Acetyl xylan esterase (AXE1) - - - 1.999e-202 657.0
TLS2_k127_591577_1 Epimerase dehydratase K06118 - 3.13.1.1 1.104e-195 616.0
TLS2_k127_591577_10 RNA-binding protein K07574 - - 0.0000000000000000006631 94.0
TLS2_k127_591577_11 - - - - 0.00000000002485 71.0
TLS2_k127_591577_2 L-rhamnose isomerase K01813 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 610.0
TLS2_k127_591577_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 540.0
TLS2_k127_591577_4 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 396.0
TLS2_k127_591577_5 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 382.0
TLS2_k127_591577_6 COG1082 Sugar phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 343.0
TLS2_k127_591577_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 300.0
TLS2_k127_591577_8 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000358 217.0
TLS2_k127_591577_9 Involved in the anomeric conversion of L-rhamnose K03534 - 5.1.3.32 0.0000000000000000000000000000000000938 138.0
TLS2_k127_5936996_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1241.0
TLS2_k127_5936996_1 COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase - - - 1.038e-194 617.0
TLS2_k127_5938948_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 1.845e-241 784.0
TLS2_k127_5938948_1 Nitrous oxide reductase K00376 - 1.7.2.4 3.754e-232 736.0
TLS2_k127_5938948_10 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 309.0
TLS2_k127_5938948_11 nitric oxide dioxygenase activity K00523,K15983 - 1.14.13.142,1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 290.0
TLS2_k127_5938948_12 dextransucrase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000223 290.0
TLS2_k127_5938948_13 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002033 276.0
TLS2_k127_5938948_14 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000232 250.0
TLS2_k127_5938948_15 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000001953 228.0
TLS2_k127_5938948_16 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000002671 201.0
TLS2_k127_5938948_17 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000006209 207.0
TLS2_k127_5938948_18 - - - - 0.00000000000000000000000000000000000000000000001475 185.0
TLS2_k127_5938948_19 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K07218 - - 0.00000000000000000000000000000000000005519 166.0
TLS2_k127_5938948_2 phosphatase activity - - - 6.119e-204 652.0
TLS2_k127_5938948_20 Cupin domain - - - 0.000000000000000000000000000000000005273 143.0
TLS2_k127_5938948_21 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000002309 138.0
TLS2_k127_5938948_22 Domain of unknown function (DUF368) K08974 - - 0.000000000000000000000000000001776 134.0
TLS2_k127_5938948_23 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000000000000001849 132.0
TLS2_k127_5938948_24 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000002205 121.0
TLS2_k127_5938948_25 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000001446 123.0
TLS2_k127_5938948_26 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000001146 113.0
TLS2_k127_5938948_27 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000008239 107.0
TLS2_k127_5938948_28 Cbs domain - - - 0.000000000000000002798 91.0
TLS2_k127_5938948_29 response regulator - - - 0.00000000000000003413 86.0
TLS2_k127_5938948_3 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 523.0
TLS2_k127_5938948_30 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000041 82.0
TLS2_k127_5938948_31 AMP binding - - - 0.00000000000001074 86.0
TLS2_k127_5938948_32 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000009823 69.0
TLS2_k127_5938948_33 NosL K19342 - - 0.00000004345 61.0
TLS2_k127_5938948_34 Cytochrome c - - - 0.0000001943 61.0
TLS2_k127_5938948_35 cell cycle K05589,K12065,K13052 - - 0.000001297 57.0
TLS2_k127_5938948_36 Cytochrome b(N-terminal)/b6/petB K00412 - - 0.00001316 53.0
TLS2_k127_5938948_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 480.0
TLS2_k127_5938948_5 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 474.0
TLS2_k127_5938948_6 Alcohol dehydrogenase GroES-like domain K00008,K00148,K18369 - 1.1.1.14,1.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 454.0
TLS2_k127_5938948_7 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 395.0
TLS2_k127_5938948_8 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 333.0
TLS2_k127_5938948_9 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 328.0
TLS2_k127_5946872_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 556.0
TLS2_k127_5946872_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 477.0
TLS2_k127_5946872_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000003875 148.0
TLS2_k127_5946872_11 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000008785 155.0
TLS2_k127_5946872_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000004442 134.0
TLS2_k127_5946872_13 - - - - 0.000000000000000001117 90.0
TLS2_k127_5946872_14 - - - - 0.000000000000008271 80.0
TLS2_k127_5946872_15 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.00000003121 62.0
TLS2_k127_5946872_16 PilZ domain - - - 0.0000004342 58.0
TLS2_k127_5946872_17 Predicted membrane protein (DUF2085) - - - 0.00005867 54.0
TLS2_k127_5946872_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 387.0
TLS2_k127_5946872_3 PFAM PfkB domain protein K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 348.0
TLS2_k127_5946872_4 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 325.0
TLS2_k127_5946872_5 GTPase activity K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 312.0
TLS2_k127_5946872_6 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 286.0
TLS2_k127_5946872_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002007 263.0
TLS2_k127_5946872_8 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004348 249.0
TLS2_k127_5946872_9 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000000001115 175.0
TLS2_k127_5960149_0 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000001074 233.0
TLS2_k127_5960149_3 helix_turn_helix, Lux Regulon - - - 0.0000003563 62.0
TLS2_k127_596573_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 475.0
TLS2_k127_596573_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 410.0
TLS2_k127_596573_10 TonB C terminal - - - 0.000000001701 69.0
TLS2_k127_596573_11 PFAM oxidoreductase - - - 0.000009598 50.0
TLS2_k127_596573_2 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000001446 269.0
TLS2_k127_596573_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000002903 243.0
TLS2_k127_596573_4 Amidohydrolase family K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000007647 241.0
TLS2_k127_596573_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000002665 223.0
TLS2_k127_596573_6 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.0000000000000000000000000000000000000000000000000246 192.0
TLS2_k127_596573_7 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000006893 182.0
TLS2_k127_596573_8 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000001079 94.0
TLS2_k127_596573_9 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000005771 73.0
TLS2_k127_5973749_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 1.666e-266 848.0
TLS2_k127_5973749_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 454.0
TLS2_k127_5973749_2 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 324.0
TLS2_k127_5973749_3 Exonuclease K07502 - - 0.0000000000000000000000000000000000000000000000000000000000008262 226.0
TLS2_k127_5973749_4 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000003894 212.0
TLS2_k127_5973749_5 PRC-barrel domain - - - 0.000000000000000000000000000000000000000000005407 166.0
TLS2_k127_5973749_6 Binds the 23S rRNA K02909 - - 0.00000000000000000000000002823 110.0
TLS2_k127_604153_0 Urocanase C-terminal domain K01712 - 4.2.1.49 1.077e-251 787.0
TLS2_k127_604153_1 choline dehydrogenase activity - - - 4.205e-214 681.0
TLS2_k127_604153_10 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 321.0
TLS2_k127_604153_11 peroxidase activity K00435 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009956 278.0
TLS2_k127_604153_12 PFAM superoxide dismutase, copper zinc binding K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000001251 209.0
TLS2_k127_604153_13 - - - - 0.000000000000000000000000000004239 128.0
TLS2_k127_604153_15 general stress protein - - - 0.0000000000000000000002253 100.0
TLS2_k127_604153_16 AAA ATPase domain - - - 0.000000001506 70.0
TLS2_k127_604153_2 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 603.0
TLS2_k127_604153_3 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 560.0
TLS2_k127_604153_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 525.0
TLS2_k127_604153_5 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 488.0
TLS2_k127_604153_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 455.0
TLS2_k127_604153_7 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 405.0
TLS2_k127_604153_8 PFAM FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 377.0
TLS2_k127_604153_9 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 351.0
TLS2_k127_6055254_0 GDYXXLXY protein - - - 0.00000000000000000000000003729 120.0
TLS2_k127_6055254_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000074 102.0
TLS2_k127_6055254_2 ECF sigma factor - - - 0.000000000000001053 79.0
TLS2_k127_6055254_3 Predicted membrane protein (DUF2157) - - - 0.000000003952 63.0
TLS2_k127_6056627_0 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 392.0
TLS2_k127_6056627_1 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 376.0
TLS2_k127_6056627_10 glycolate biosynthetic process K07025 - - 0.0000000000000000000000000000002721 137.0
TLS2_k127_6056627_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001863 259.0
TLS2_k127_6056627_3 Involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000003892 249.0
TLS2_k127_6056627_4 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000003521 211.0
TLS2_k127_6056627_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000001576 201.0
TLS2_k127_6056627_6 TrkA-C domain - - - 0.000000000000000000000000000000000000000000000000008854 185.0
TLS2_k127_6056627_7 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000006611 178.0
TLS2_k127_6056627_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000011 173.0
TLS2_k127_6056627_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000002012 144.0
TLS2_k127_6137515_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 424.0
TLS2_k127_6137515_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 390.0
TLS2_k127_6137515_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000003792 238.0
TLS2_k127_6137515_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000088 88.0
TLS2_k127_6154606_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.03e-204 649.0
TLS2_k127_6154606_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 422.0
TLS2_k127_6154606_10 PFAM Rhomboid family - - - 0.000000000006527 69.0
TLS2_k127_6154606_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000001422 70.0
TLS2_k127_6154606_12 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000005917 69.0
TLS2_k127_6154606_13 - - - - 0.00005074 55.0
TLS2_k127_6154606_14 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0001541 48.0
TLS2_k127_6154606_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 395.0
TLS2_k127_6154606_3 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000001618 228.0
TLS2_k127_6154606_4 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000003385 237.0
TLS2_k127_6154606_5 Extracellular repeat protein, HAF family - - - 0.00000000000000000000000000000001163 133.0
TLS2_k127_6154606_6 - - - - 0.000000000000000000000012 107.0
TLS2_k127_6154606_7 Multiple resistance and pH regulation protein F K05570 - - 0.000000000000004682 79.0
TLS2_k127_6154606_8 Domain related to MnhB subunit of Na+/H+ antiporter - - - 0.00000000000003939 78.0
TLS2_k127_6154606_9 Na H antiporter K05571 - - 0.000000000005662 74.0
TLS2_k127_6184172_0 pyrroloquinoline quinone binding K01206,K01218 - 3.2.1.51,3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 433.0
TLS2_k127_6184172_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 362.0
TLS2_k127_6210182_0 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 451.0
TLS2_k127_6210182_1 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001007 269.0
TLS2_k127_6210182_2 phosphorelay signal transduction system K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000001758 240.0
TLS2_k127_6243365_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 367.0
TLS2_k127_6243365_1 - - - - 0.000000000000000000000000007873 116.0
TLS2_k127_6243365_2 Metallo-beta-lactamase superfamily - - - 0.00000000001051 67.0
TLS2_k127_6243365_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000003049 59.0
TLS2_k127_625989_0 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 428.0
TLS2_k127_625989_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 402.0
TLS2_k127_625989_2 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 321.0
TLS2_k127_625989_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000002443 188.0
TLS2_k127_625989_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000212 164.0
TLS2_k127_625989_5 Methyltransferase type 12 - - - 0.000000000000000000000008863 110.0
TLS2_k127_625989_6 Methionine biosynthesis protein MetW - - - 0.0000000000000000001586 98.0
TLS2_k127_6271903_0 Glutamine synthetase type III K01915 - 6.3.1.2 1.177e-304 951.0
TLS2_k127_6271903_1 UvrD/REP helicase N-terminal domain - - - 1.099e-238 783.0
TLS2_k127_6271903_2 PD-(D/E)XK nuclease superfamily - - - 1.216e-228 746.0
TLS2_k127_6271903_3 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 626.0
TLS2_k127_6271903_4 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 357.0
TLS2_k127_6271903_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 332.0
TLS2_k127_6271903_6 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 308.0
TLS2_k127_6271903_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 299.0
TLS2_k127_6271903_8 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000212 151.0
TLS2_k127_6271903_9 Transcriptional regulator PadR-like family - - - 0.000000000000000000005728 97.0
TLS2_k127_6273433_0 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 465.0
TLS2_k127_6273433_1 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 328.0
TLS2_k127_6273433_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000006939 155.0
TLS2_k127_6273433_3 dicarboxylic acid transport K11102 - - 0.0000000000000000000000000000000004783 146.0
TLS2_k127_6273433_4 protein conserved in bacteria K15539 - - 0.000000005 67.0
TLS2_k127_6273433_5 SnoaL-like domain - - - 0.00000002334 61.0
TLS2_k127_6273433_7 ubiE/COQ5 methyltransferase family - - - 0.0004058 52.0
TLS2_k127_6303513_0 CHAT domain - - - 5.051e-309 1011.0
TLS2_k127_6303513_1 Oxidoreductase - - - 2.26e-279 869.0
TLS2_k127_6303513_10 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 422.0
TLS2_k127_6303513_11 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 437.0
TLS2_k127_6303513_12 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 401.0
TLS2_k127_6303513_13 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 407.0
TLS2_k127_6303513_14 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 409.0
TLS2_k127_6303513_15 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 361.0
TLS2_k127_6303513_16 Phytanoyl-CoA dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 364.0
TLS2_k127_6303513_17 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) K01083 - 3.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002239 291.0
TLS2_k127_6303513_18 BlaR1 peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003619 295.0
TLS2_k127_6303513_19 Bacterial transcriptional repressor C-terminal K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002862 273.0
TLS2_k127_6303513_2 Carboxypeptidase regulatory-like domain - - - 7.411e-236 763.0
TLS2_k127_6303513_20 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000472 275.0
TLS2_k127_6303513_21 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000000000000000000000000001033 241.0
TLS2_k127_6303513_22 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000003557 237.0
TLS2_k127_6303513_23 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000517 231.0
TLS2_k127_6303513_24 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009965 222.0
TLS2_k127_6303513_25 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000000000000000003761 201.0
TLS2_k127_6303513_26 Gluconate 2-dehydrogenase subunit 3 - - - 0.00000000000000000000000000000000000000000000000000009786 200.0
TLS2_k127_6303513_27 Disulphide isomerase - - - 0.000000000000000000000000000000000000000000000000001472 187.0
TLS2_k127_6303513_28 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000003512 190.0
TLS2_k127_6303513_29 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000605 190.0
TLS2_k127_6303513_3 Amidase K01426 - 3.5.1.4 7.316e-219 700.0
TLS2_k127_6303513_30 membrane - - - 0.0000000000000000000000000000000000000000000003112 171.0
TLS2_k127_6303513_31 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000131 175.0
TLS2_k127_6303513_32 YCII-related domain - - - 0.00000000000000000000000000000000000000005096 166.0
TLS2_k127_6303513_33 Penicillinase repressor - - - 0.0000000000000000000000000000000000000001153 154.0
TLS2_k127_6303513_34 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000001654 151.0
TLS2_k127_6303513_35 Protein of unknown function (DUF1761) - - - 0.000000000000000000000000000000000002315 144.0
TLS2_k127_6303513_36 - - - - 0.00000000000000000000000000002271 118.0
TLS2_k127_6303513_37 - - - - 0.0000000000000000000009772 97.0
TLS2_k127_6303513_38 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000002291 107.0
TLS2_k127_6303513_39 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000096 104.0
TLS2_k127_6303513_4 His Kinase A (phosphoacceptor) domain - - - 1.478e-198 644.0
TLS2_k127_6303513_40 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000002564 96.0
TLS2_k127_6303513_43 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000128 69.0
TLS2_k127_6303513_44 - - - - 0.000000002539 65.0
TLS2_k127_6303513_45 PFAM HEPN domain - - - 0.000000008206 67.0
TLS2_k127_6303513_46 PIN domain - - - 0.0000001224 61.0
TLS2_k127_6303513_48 - - - - 0.0001312 50.0
TLS2_k127_6303513_49 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0001428 50.0
TLS2_k127_6303513_5 COG3119 Arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 572.0
TLS2_k127_6303513_50 - - - - 0.0007604 49.0
TLS2_k127_6303513_6 PFAM Na Pi-cotransporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 566.0
TLS2_k127_6303513_7 C4-dicarboxylate anaerobic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 513.0
TLS2_k127_6303513_8 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 448.0
TLS2_k127_6303513_9 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 469.0
TLS2_k127_6322564_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000001454 226.0
TLS2_k127_6322564_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000008007 127.0
TLS2_k127_6353322_0 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 518.0
TLS2_k127_6353322_1 Cleaves the N-terminal amino acid of tripeptides K01258 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 432.0
TLS2_k127_6353322_2 alginic acid biosynthetic process K01729 - 4.2.2.3 0.000000000000000000000000000000000000000000000000000000000000000000006417 259.0
TLS2_k127_6353322_3 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000002147 226.0
TLS2_k127_6353322_4 Rdx family K07401 - - 0.00000000000000000000000000000000000000008929 152.0
TLS2_k127_6353322_5 - - - - 0.0000000000000000000000000000000000000412 153.0
TLS2_k127_6354619_0 Beta-L-arabinofuranosidase, GH127 - - - 1.118e-228 733.0
TLS2_k127_6354619_1 FAD dependent oxidoreductase - - - 9.303e-223 704.0
TLS2_k127_6354619_2 NIPSNAP family containing protein - - - 0.000000000000000000000000000000001248 139.0
TLS2_k127_6354619_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000005722 130.0
TLS2_k127_6354619_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.000000000000000000003625 96.0
TLS2_k127_6367439_0 PFAM Peptidoglycan-binding domain 1 protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 419.0
TLS2_k127_6367439_1 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000000003695 164.0
TLS2_k127_6367439_2 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000001164 117.0
TLS2_k127_6367439_3 Universal stress protein - - - 0.00000000000000000000006374 104.0
TLS2_k127_6367439_4 serine-type endopeptidase activity - - - 0.0000000002066 69.0
TLS2_k127_6412327_0 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 439.0
TLS2_k127_6412327_1 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000013 267.0
TLS2_k127_6412327_2 PFAM Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000009686 230.0
TLS2_k127_6412327_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000002441 219.0
TLS2_k127_6412327_4 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000009887 188.0
TLS2_k127_6412327_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000002376 140.0
TLS2_k127_6412327_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000404 117.0
TLS2_k127_6412327_7 NhaP-type Na H and K H - - - 0.000000000007002 78.0
TLS2_k127_6412327_8 salt-induced outer membrane protein K07283 - - 0.0000000009011 72.0
TLS2_k127_6412327_9 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000001818 60.0
TLS2_k127_6435237_0 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000001208 162.0
TLS2_k127_6442036_0 Glycosyl transferases group 1 K21001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 317.0
TLS2_k127_6442036_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000004849 260.0
TLS2_k127_6442036_2 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000001818 149.0
TLS2_k127_6480923_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 422.0
TLS2_k127_6480923_1 Beta-lactamase class C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 388.0
TLS2_k127_6480923_2 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 338.0
TLS2_k127_6480923_3 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000000000006889 171.0
TLS2_k127_6480923_4 Putative prokaryotic signal transducing protein - - - 0.00002599 49.0
TLS2_k127_6503685_0 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 430.0
TLS2_k127_6503685_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 411.0
TLS2_k127_6503685_10 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000002771 154.0
TLS2_k127_6503685_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000001298 154.0
TLS2_k127_6503685_12 Putative adhesin - - - 0.0000000000000000000000000000001335 138.0
TLS2_k127_6503685_13 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000001471 132.0
TLS2_k127_6503685_14 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000001795 89.0
TLS2_k127_6503685_15 - K01992 - - 0.000000000000001375 87.0
TLS2_k127_6503685_16 Cysteine methyltransferase K00567 - 2.1.1.63 0.000000000000001567 81.0
TLS2_k127_6503685_17 - - - - 0.000000000002674 78.0
TLS2_k127_6503685_18 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.00000001638 66.0
TLS2_k127_6503685_2 Na dependent nucleoside K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 408.0
TLS2_k127_6503685_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 377.0
TLS2_k127_6503685_4 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 335.0
TLS2_k127_6503685_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 320.0
TLS2_k127_6503685_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 321.0
TLS2_k127_6503685_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 315.0
TLS2_k127_6503685_8 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000007536 236.0
TLS2_k127_6503685_9 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000004141 213.0
TLS2_k127_6503763_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 509.0
TLS2_k127_6503763_1 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000093 372.0
TLS2_k127_6503763_2 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000001329 249.0
TLS2_k127_6503763_3 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000002223 205.0
TLS2_k127_6503763_4 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.00000000000000000000000000000000000000000000000000186 193.0
TLS2_k127_6503763_5 anaphase-promoting complex-dependent catabolic process - - - 0.0000000000000000000000000000000003237 138.0
TLS2_k127_6503763_6 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000002352 117.0
TLS2_k127_6503763_7 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000000000000001142 97.0
TLS2_k127_6503763_8 PQ loop repeat K15383 - - 0.000003952 58.0
TLS2_k127_6505818_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 526.0
TLS2_k127_6505818_1 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000007358 190.0
TLS2_k127_6505818_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000005925 70.0
TLS2_k127_6507380_0 Amidohydrolase family - - - 3.034e-279 875.0
TLS2_k127_6507380_1 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 642.0
TLS2_k127_6507380_10 Transcriptional regulatory protein, C terminal - - - 0.000000000000004677 78.0
TLS2_k127_6507380_11 - - - - 0.00000000000003918 86.0
TLS2_k127_6507380_12 Arylsulfatase - - - 0.000000001902 68.0
TLS2_k127_6507380_13 Domain of Unknown Function (DUF1080) - - - 0.00000001089 63.0
TLS2_k127_6507380_14 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000006962 53.0
TLS2_k127_6507380_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 508.0
TLS2_k127_6507380_3 Hep Hag repeat protein K01179,K01207 - 3.2.1.4,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000001898 288.0
TLS2_k127_6507380_4 Uncharacterized protein conserved in bacteria (DUF2130) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006789 248.0
TLS2_k127_6507380_5 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000001166 191.0
TLS2_k127_6507380_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000003276 163.0
TLS2_k127_6507380_7 Vault protein inter-alpha-trypsin domain - - - 0.000000000000000000000000000000000000000004182 160.0
TLS2_k127_6507380_8 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 0.00000000000000000000000000000000003231 157.0
TLS2_k127_6507380_9 C-terminal region of aryl-sulfatase - - - 0.000000000000000000000000003972 118.0
TLS2_k127_6513655_0 FtsX-like permease family - - - 1.72e-226 729.0
TLS2_k127_6513655_1 AlkA N-terminal domain K13529 - 3.2.2.21 4.71e-215 682.0
TLS2_k127_6513655_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 545.0
TLS2_k127_6513655_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 426.0
TLS2_k127_6513655_4 Sir2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 317.0
TLS2_k127_6513655_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000003436 272.0
TLS2_k127_6513655_6 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000001082 241.0
TLS2_k127_6513655_7 pseudouridine synthase activity K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000006405 202.0
TLS2_k127_6513655_8 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000009851 202.0
TLS2_k127_6513655_9 Pfam:Methyltransf_6 - - - 0.00000000000000000008331 95.0
TLS2_k127_6566435_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 2.242e-304 948.0
TLS2_k127_6566435_1 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 421.0
TLS2_k127_6566435_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 357.0
TLS2_k127_6566435_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006255 275.0
TLS2_k127_6566435_4 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
TLS2_k127_6566435_5 zinc ion binding K02347,K04477 - - 0.00000000000000000000000000000000000000000000000000000000001829 221.0
TLS2_k127_6566435_6 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000009692 208.0
TLS2_k127_6566435_7 - - - - 0.000000000000000000000000000000000000000000000000003071 187.0
TLS2_k127_6566435_8 Ndr family - - - 0.0000000000000000000000002143 115.0
TLS2_k127_6575083_0 Concanavalin A-like lectin/glucanases superfamily - - - 0.0 1030.0
TLS2_k127_6575083_1 Protein of unknown function (DUF1501) - - - 4.938e-215 677.0
TLS2_k127_6575083_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 585.0
TLS2_k127_6575083_3 membrane K07148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 385.0
TLS2_k127_6575083_4 Belongs to the glycosyl hydrolase 2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 367.0
TLS2_k127_6575083_5 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001685 256.0
TLS2_k127_6575083_6 Iron-containing alcohol dehydrogenase K11173 - 1.1.99.24 0.000000000000000000000000000000000000000000000000000000000000000001141 229.0
TLS2_k127_6575083_7 - - - - 0.000000000000000000000000000000000000000000000000000000000002181 219.0
TLS2_k127_6575083_8 PIN domain - - - 0.000000000000000000000000000000000000000000003145 167.0
TLS2_k127_6575083_9 Citrate transporter - - - 0.0002451 48.0
TLS2_k127_6578156_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 411.0
TLS2_k127_6578156_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000008003 100.0
TLS2_k127_6578410_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.097e-271 843.0
TLS2_k127_6578410_1 PFAM 4Fe-4S K00184,K21308 - - 3.876e-245 783.0
TLS2_k127_6578410_10 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000000001364 78.0
TLS2_k127_6578410_11 - - - - 0.0000000003233 70.0
TLS2_k127_6578410_2 Polysulphide reductase, NrfD K00185 - - 1.208e-203 670.0
TLS2_k127_6578410_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 392.0
TLS2_k127_6578410_4 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 364.0
TLS2_k127_6578410_5 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002115 290.0
TLS2_k127_6578410_6 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000003518 249.0
TLS2_k127_6578410_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000003375 237.0
TLS2_k127_6578410_8 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000002535 214.0
TLS2_k127_6578410_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000006347 219.0
TLS2_k127_6583078_0 An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH K09159 - - 1.92e-220 700.0
TLS2_k127_6583078_1 Peptidase family M49 - - - 4.223e-208 662.0
TLS2_k127_6583078_10 Nickel-dependent hydrogenase - - - 0.0000000000000000005381 87.0
TLS2_k127_6583078_11 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0002251 51.0
TLS2_k127_6583078_2 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 556.0
TLS2_k127_6583078_3 PFAM Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 486.0
TLS2_k127_6583078_4 ATPase domain of DNA mismatch repair MUTS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 490.0
TLS2_k127_6583078_5 TIGRFAM glycosyltransferase, MGT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001317 284.0
TLS2_k127_6583078_6 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000007534 200.0
TLS2_k127_6583078_7 Putative restriction endonuclease - - - 0.0000000000000000000000000003886 123.0
TLS2_k127_6583078_8 - - - - 0.00000000000000000000000005449 112.0
TLS2_k127_6583078_9 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000006036 112.0
TLS2_k127_6585135_0 Multi-copper - - - 1.423e-275 864.0
TLS2_k127_6585135_1 copper resistance K07233 - - 0.00000000000000000000000000000000000000000000000000000000002401 233.0
TLS2_k127_6585717_0 Carboxypeptidase regulatory-like domain - - - 3.005e-279 891.0
TLS2_k127_6586411_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.387e-213 672.0
TLS2_k127_6586411_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 563.0
TLS2_k127_6586411_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 567.0
TLS2_k127_6586411_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 469.0
TLS2_k127_6586411_4 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 452.0
TLS2_k127_6586411_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 390.0
TLS2_k127_6586411_6 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001588 263.0
TLS2_k127_6586411_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000001409 215.0
TLS2_k127_6592746_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007503 256.0
TLS2_k127_6592746_1 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000003555 202.0
TLS2_k127_6592746_2 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.0000000000000000000000000000000000000003993 162.0
TLS2_k127_6592746_3 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000006948 150.0
TLS2_k127_6594566_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 9.036e-217 682.0
TLS2_k127_6594566_1 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 613.0
TLS2_k127_6594566_2 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 436.0
TLS2_k127_6594566_3 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 0.0000000000000000000000000000000000000000000000000000000000000006044 222.0
TLS2_k127_6598311_0 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 491.0
TLS2_k127_6598311_1 protein catabolic process K03420,K13525,K17681 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 411.0
TLS2_k127_6598311_2 Oxidoreductase domain protein - - - 0.0000000000000005216 78.0
TLS2_k127_6608725_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 320.0
TLS2_k127_6608725_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 317.0
TLS2_k127_6608725_2 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000189 286.0
TLS2_k127_6608725_3 STAS domain K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000007664 232.0
TLS2_k127_6608725_4 Putative esterase - - - 0.000000000000000000000000000000000000000000007946 173.0
TLS2_k127_6608725_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000002133 167.0
TLS2_k127_6608725_6 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000005275 176.0
TLS2_k127_6608725_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000001878 140.0
TLS2_k127_6608725_8 Sporulation and spore germination - - - 0.00000000000000002466 96.0
TLS2_k127_6614116_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 593.0
TLS2_k127_6614116_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000785 265.0
TLS2_k127_6614116_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000001178 199.0
TLS2_k127_6614116_3 peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000001807 187.0
TLS2_k127_6614116_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000001002 144.0
TLS2_k127_6614116_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000005844 142.0
TLS2_k127_6614116_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000006977 122.0
TLS2_k127_6614116_7 outer membrane autotransporter barrel domain protein - - - 0.00001898 56.0
TLS2_k127_6645883_0 of the double-stranded beta helix - - - 0.00000000000000000000000000001089 126.0
TLS2_k127_6645883_1 DNA-binding ferritin-like protein (Oxidative damage protectant) K04047 - - 0.000000000000000000001088 99.0
TLS2_k127_6645883_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000007283 79.0
TLS2_k127_6649600_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 1.386e-248 798.0
TLS2_k127_6649600_1 COG0471 Di- and tricarboxylate transporters K03319,K09477,K11106,K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 583.0
TLS2_k127_6649600_10 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000007277 180.0
TLS2_k127_6649600_11 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.00000000000000000000000000000002366 146.0
TLS2_k127_6649600_12 toll-like receptor K18808 - - 0.0000003601 62.0
TLS2_k127_6649600_13 peptidyl-tyrosine sulfation - - - 0.0001128 54.0
TLS2_k127_6649600_15 Cupin 2, conserved barrel domain protein - - - 0.0003618 51.0
TLS2_k127_6649600_2 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 517.0
TLS2_k127_6649600_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 417.0
TLS2_k127_6649600_4 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008694 392.0
TLS2_k127_6649600_5 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 363.0
TLS2_k127_6649600_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 374.0
TLS2_k127_6649600_7 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000496 228.0
TLS2_k127_6649600_8 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000007183 222.0
TLS2_k127_6649600_9 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000581 188.0
TLS2_k127_6653743_0 Belongs to the peptidase M16 family K07263 - - 0.0 1088.0
TLS2_k127_6653743_1 ABC-type antimicrobial peptide transport system, permease component - - - 2.874e-197 652.0
TLS2_k127_6653743_2 UPF0365 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 496.0
TLS2_k127_6653743_3 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 415.0
TLS2_k127_6653743_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 290.0
TLS2_k127_6653743_5 ABC-type antimicrobial peptide transport system, permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008037 296.0
TLS2_k127_6653743_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000003592 236.0
TLS2_k127_6653743_7 - - - - 0.000000000000000000000000000000000000000001434 164.0
TLS2_k127_6653743_8 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000000008645 104.0
TLS2_k127_6654041_0 PFAM PBS lyase - - - 7.155e-257 811.0
TLS2_k127_6654041_1 Serine aminopeptidase, S33 - - - 0.000004436 49.0
TLS2_k127_6657075_0 Cytochrome c - - - 0.0 1184.0
TLS2_k127_6657075_1 Carboxypeptidase regulatory-like domain - - - 0.0 1157.0
TLS2_k127_6657075_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001507 266.0
TLS2_k127_6657075_11 photoreceptor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001617 256.0
TLS2_k127_6657075_12 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001631 254.0
TLS2_k127_6657075_13 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001978 249.0
TLS2_k127_6657075_14 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000001673 217.0
TLS2_k127_6657075_15 hydrolase activity, acting on ester bonds K15357,K19311 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0044237,GO:0044248 3.5.1.106 0.00000000000000000000000000000000000000000000000009118 190.0
TLS2_k127_6657075_16 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000002948 189.0
TLS2_k127_6657075_17 KR domain - - - 0.00000000000000000000000000000000000000000000003105 178.0
TLS2_k127_6657075_18 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000001204 184.0
TLS2_k127_6657075_19 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000001291 181.0
TLS2_k127_6657075_2 efflux transmembrane transporter activity - - - 2.948e-278 880.0
TLS2_k127_6657075_20 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000001087 167.0
TLS2_k127_6657075_21 TIR domain - - - 0.000000000000000000000000000000000000007633 159.0
TLS2_k127_6657075_22 Pfam Response regulator receiver - - - 0.0000000000000000000000000000000000001475 145.0
TLS2_k127_6657075_23 Histidine kinase-like ATPases K02480 - 2.7.13.3 0.000000000000000000000000105 108.0
TLS2_k127_6657075_24 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000007621 99.0
TLS2_k127_6657075_25 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000533 83.0
TLS2_k127_6657075_27 - - - - 0.00003743 57.0
TLS2_k127_6657075_3 Amidohydrolase family - - - 1.347e-225 713.0
TLS2_k127_6657075_4 TonB-dependent receptor - - - 5.826e-214 698.0
TLS2_k127_6657075_5 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 617.0
TLS2_k127_6657075_6 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 575.0
TLS2_k127_6657075_7 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 372.0
TLS2_k127_6657075_8 Phosphoinositide phospholipase C, Ca2+-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 334.0
TLS2_k127_6657075_9 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 298.0
TLS2_k127_6660299_0 PFAM Bacterial low temperature requirement A protein (LtrA) - - - 0.00000000000000000000000000000000000000000000000000005067 203.0
TLS2_k127_6660299_1 - - - - 0.0000000000000000000000000000000000000000000000364 177.0
TLS2_k127_6660299_2 Yhs domain-containing protein - - - 0.0000000000000000000000000000000000000000001175 164.0
TLS2_k127_6675778_0 transport - - - 6.217e-278 893.0
TLS2_k127_6675778_1 transport - - - 6.503e-268 862.0
TLS2_k127_6675778_2 Aldo/keto reductase family - - - 0.00000000000002281 73.0
TLS2_k127_6681561_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006701 278.0
TLS2_k127_6681561_1 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000008407 243.0
TLS2_k127_6681561_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000008241 188.0
TLS2_k127_6681561_3 HEAT repeat - - - 0.0002911 52.0
TLS2_k127_6681648_0 WD40-like Beta Propeller Repeat - - - 6.13e-237 769.0
TLS2_k127_6681648_1 protein conserved in bacteria - - - 8.966e-218 700.0
TLS2_k127_6681648_10 Ami_2 - - - 0.00000003473 65.0
TLS2_k127_6681648_2 COG3119 Arylsulfatase A K01565 - 3.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 591.0
TLS2_k127_6681648_3 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 511.0
TLS2_k127_6681648_4 RecQ zinc-binding K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 495.0
TLS2_k127_6681648_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 344.0
TLS2_k127_6681648_6 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000002802 216.0
TLS2_k127_6681648_7 permease - - - 0.000000000000000000000000000000000000000000000000000002072 209.0
TLS2_k127_6681648_8 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000003999 182.0
TLS2_k127_6681648_9 COG3030 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.00000000000000000000000008983 113.0
TLS2_k127_6691083_0 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 561.0
TLS2_k127_6691083_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 508.0
TLS2_k127_6691083_2 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002791 256.0
TLS2_k127_6691083_3 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000139 198.0
TLS2_k127_6691083_4 YsiA-like protein, C-terminal region K13770 - - 0.0000000000000000000000000000000000000000000005663 174.0
TLS2_k127_6691083_5 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000006329 168.0
TLS2_k127_6691083_6 - K07018 - - 0.000000000000000000000000000000000000000004502 164.0
TLS2_k127_6691083_7 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000348 149.0
TLS2_k127_6691083_8 Alpha beta hydrolase - - - 0.0000000000000001571 92.0
TLS2_k127_6691083_9 PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.000001664 60.0
TLS2_k127_6692427_0 Squalene-hopene cyclase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 495.0
TLS2_k127_6692427_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000003572 91.0
TLS2_k127_6698530_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 444.0
TLS2_k127_6698530_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 310.0
TLS2_k127_6698530_2 GAF domain - - - 0.000000000000000000000000000001035 129.0
TLS2_k127_6698530_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000001414 71.0
TLS2_k127_6707863_0 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 518.0
TLS2_k127_6707863_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 336.0
TLS2_k127_6707863_10 cellulase activity K01209 - 3.2.1.55 0.000000009419 67.0
TLS2_k127_6707863_11 virulence factor K03980 - - 0.0000002411 64.0
TLS2_k127_6707863_2 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 314.0
TLS2_k127_6707863_3 dextransucrase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 305.0
TLS2_k127_6707863_4 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001021 255.0
TLS2_k127_6707863_5 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000006884 222.0
TLS2_k127_6707863_6 Methyltransferase domain - - - 0.0000000000000000000000000000002234 139.0
TLS2_k127_6707863_7 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.0000000000000000000000000000002992 139.0
TLS2_k127_6707863_8 - - - - 0.000000000000000000000004216 111.0
TLS2_k127_6707863_9 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000004708 69.0
TLS2_k127_6714938_0 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 499.0
TLS2_k127_6716269_0 4-alpha-glucanotransferase K00700,K00705,K02438,K06044 - 2.4.1.18,2.4.1.25,3.2.1.196,5.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 606.0
TLS2_k127_6716269_1 COG1228 Imidazolonepropionase and related K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 568.0
TLS2_k127_6716269_10 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001735 250.0
TLS2_k127_6716269_11 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000002332 158.0
TLS2_k127_6716269_12 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000000009235 109.0
TLS2_k127_6716269_13 Catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate K00619 - 2.3.1.1 0.000000000000000000000006296 115.0
TLS2_k127_6716269_14 glycogen debranching enzyme GlgX K01214 - 3.2.1.68 0.00000000006405 64.0
TLS2_k127_6716269_2 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 353.0
TLS2_k127_6716269_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 327.0
TLS2_k127_6716269_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 336.0
TLS2_k127_6716269_5 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 323.0
TLS2_k127_6716269_6 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 325.0
TLS2_k127_6716269_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001508 288.0
TLS2_k127_6716269_8 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001077 286.0
TLS2_k127_6716269_9 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000001024 260.0
TLS2_k127_6725610_0 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 526.0
TLS2_k127_6725610_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K22319 - 6.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 487.0
TLS2_k127_6725610_10 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000007641 106.0
TLS2_k127_6725610_11 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.000000000000000000004533 100.0
TLS2_k127_6725610_12 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - 0.000000000000004932 78.0
TLS2_k127_6725610_13 Domain of unknown function (DUF1844) - - - 0.00000000000002286 83.0
TLS2_k127_6725610_15 - - - - 0.0002456 48.0
TLS2_k127_6725610_2 FAD binding domain K05712,K16022,K20943,K20944 - 1.14.13.127,1.14.13.219,1.14.13.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 466.0
TLS2_k127_6725610_3 Protein of unknown function (DUF3419) K13622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008881 447.0
TLS2_k127_6725610_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 442.0
TLS2_k127_6725610_5 kinase activity K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 301.0
TLS2_k127_6725610_6 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 315.0
TLS2_k127_6725610_7 dolichyl monophosphate biosynthetic process K00981,K18678 - 2.7.1.182,2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004823 302.0
TLS2_k127_6725610_8 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007918 279.0
TLS2_k127_6725610_9 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000007583 243.0
TLS2_k127_6734264_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 554.0
TLS2_k127_6734264_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 365.0
TLS2_k127_6734264_10 - - - - 0.0000000000000000006343 102.0
TLS2_k127_6734264_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 349.0
TLS2_k127_6734264_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 315.0
TLS2_k127_6734264_4 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 314.0
TLS2_k127_6734264_5 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004058 236.0
TLS2_k127_6734264_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000002255 181.0
TLS2_k127_6734264_7 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000004548 179.0
TLS2_k127_6734264_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000004782 114.0
TLS2_k127_6770973_0 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 582.0
TLS2_k127_6770973_1 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000001343 183.0
TLS2_k127_6770973_2 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000005238 156.0
TLS2_k127_6770973_4 PFAM Ethyl tert-butyl ether degradation EthD - - - 0.0000000000000006394 84.0
TLS2_k127_6770973_5 COG1520 FOG WD40-like repeat - - - 0.00003087 48.0
TLS2_k127_6786603_0 kinase activity K22129 - 2.7.1.219,2.7.1.220 0.00000000000000000000000000000000000000000000000000000000005746 218.0
TLS2_k127_6786603_1 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000005394 125.0
TLS2_k127_6790534_0 Tetratricopeptide repeat - - - 0.0000000000000000114 97.0
TLS2_k127_6791917_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 4.178e-317 992.0
TLS2_k127_6791917_1 neurotransmitter:sodium symporter activity K03308,K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 470.0
TLS2_k127_6791917_2 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 449.0
TLS2_k127_6791917_3 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 336.0
TLS2_k127_6791917_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000331 263.0
TLS2_k127_6791917_5 glycerophosphodiester phosphodiesterase activity K01126 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000007913 214.0
TLS2_k127_6791917_6 RES - - - 0.000000000000000000000000000000000000000000004273 174.0
TLS2_k127_6791917_7 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000003285 112.0
TLS2_k127_6796225_0 HEAT repeat-containing protein - - - 0.000000000000000000000001756 116.0
TLS2_k127_6796225_1 TIR domain - - - 0.0000000001142 74.0
TLS2_k127_6796225_2 AAA-4 family - - - 0.0000003775 54.0
TLS2_k127_6800030_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1534.0
TLS2_k127_6800030_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 8.757e-216 680.0
TLS2_k127_6800030_10 formate dehydrogenase (NAD+) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001993 257.0
TLS2_k127_6800030_11 PFAM WD-40 repeat - - - 0.000000000000000000000000000000000000000000000003401 197.0
TLS2_k127_6800030_12 UPF0060 membrane protein K09771 - - 0.0000000000000000000000000000004811 127.0
TLS2_k127_6800030_13 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000002456 112.0
TLS2_k127_6800030_14 peptidyl-tyrosine sulfation - - - 0.0000000000000000009808 100.0
TLS2_k127_6800030_15 - - - - 0.00001786 52.0
TLS2_k127_6800030_2 4 iron, 4 sulfur cluster binding - - - 1.15e-199 640.0
TLS2_k127_6800030_3 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 603.0
TLS2_k127_6800030_4 Penicillin K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 529.0
TLS2_k127_6800030_5 Enolase C-terminal domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 514.0
TLS2_k127_6800030_6 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 466.0
TLS2_k127_6800030_7 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 401.0
TLS2_k127_6800030_8 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 323.0
TLS2_k127_6800030_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 294.0
TLS2_k127_6832570_0 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000008248 203.0
TLS2_k127_6832570_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000003835 82.0
TLS2_k127_6832570_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000007531 81.0
TLS2_k127_6851258_0 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000002534 109.0
TLS2_k127_6851258_1 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000001682 86.0
TLS2_k127_6851258_2 Thioesterase superfamily - - - 0.0000000000001008 81.0
TLS2_k127_6851258_3 Glycine/sarcosine/betaine reductase component B subunits K10671 - 1.21.4.2 0.00003744 48.0
TLS2_k127_6862608_0 peptidase - - - 0.0000000000000000000000000000000000000000000000001984 188.0
TLS2_k127_6862608_1 Domain of unknown function (DUF4440) - - - 0.00000008358 63.0
TLS2_k127_6862608_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000005218 58.0
TLS2_k127_6872509_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 477.0
TLS2_k127_6907133_0 PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal K01684 - 4.2.1.6 4.078e-201 633.0
TLS2_k127_6907133_1 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 589.0
TLS2_k127_6907133_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 374.0
TLS2_k127_6907133_3 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003743 262.0
TLS2_k127_6907133_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000755 233.0
TLS2_k127_6907133_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000001199 220.0
TLS2_k127_6907133_6 Transposase - - - 0.000000000000000000000000000000000009542 146.0
TLS2_k127_6907133_7 - - - - 0.0000000000000000000000000001437 117.0
TLS2_k127_6907133_8 Putative transposase - - - 0.000000000000000000361 95.0
TLS2_k127_6907133_9 Peptidase family M28 - - - 0.00000004609 59.0
TLS2_k127_6952010_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 481.0
TLS2_k127_7006044_0 alpha amylase catalytic K01182,K05343 - 3.2.1.1,3.2.1.10,5.4.99.16 0.0 1336.0
TLS2_k127_7006044_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 2.984e-304 949.0
TLS2_k127_7006044_10 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 319.0
TLS2_k127_7006044_11 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000002994 265.0
TLS2_k127_7006044_12 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000881 254.0
TLS2_k127_7006044_13 aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000003992 249.0
TLS2_k127_7006044_14 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000008966 245.0
TLS2_k127_7006044_15 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000004876 241.0
TLS2_k127_7006044_16 ethanolamine catabolic process K04027 - - 0.0000000000000000000000000000000000001048 144.0
TLS2_k127_7006044_17 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000000967 119.0
TLS2_k127_7006044_18 YbbR-like protein - - - 0.000000000000000000000000005878 123.0
TLS2_k127_7006044_19 efflux transmembrane transporter activity - - - 0.0000000000000000000000003675 108.0
TLS2_k127_7006044_2 Alpha amylase, catalytic domain - - - 1.98e-269 864.0
TLS2_k127_7006044_20 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000493 111.0
TLS2_k127_7006044_21 SEC-C Motif Domain Protein - - - 0.0000000000000000000000006962 119.0
TLS2_k127_7006044_22 Tetratricopeptide repeat - - - 0.00000000000000000000004131 108.0
TLS2_k127_7006044_23 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000004357 91.0
TLS2_k127_7006044_24 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000001149 80.0
TLS2_k127_7006044_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.302e-259 827.0
TLS2_k127_7006044_4 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 2.408e-240 762.0
TLS2_k127_7006044_5 Alpha amylase, catalytic domain K01176,K01236 - 3.2.1.1,3.2.1.141 2.74e-211 674.0
TLS2_k127_7006044_6 mandelate racemase muconate lactonizing K08323 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0047929,GO:0071704,GO:1901575 4.2.1.8 4.218e-210 669.0
TLS2_k127_7006044_7 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 406.0
TLS2_k127_7006044_8 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 337.0
TLS2_k127_7006044_9 Gaf domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 319.0
TLS2_k127_7020881_0 Thiamine pyrophosphate enzyme, central domain K00156 - 1.2.5.1 1.348e-303 945.0
TLS2_k127_7020881_1 COG3387 Glucoamylase and related glycosyl hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 619.0
TLS2_k127_7020881_10 carboxylic acid catabolic process - - - 0.0000000000002599 75.0
TLS2_k127_7020881_11 PFAM membrane protein of K08972 - - 0.000000000008325 70.0
TLS2_k127_7020881_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 541.0
TLS2_k127_7020881_3 FAD linked oxidase domain protein K06911 - - 0.0000000000000000000000000000000000000000000000000000000000003485 226.0
TLS2_k127_7020881_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000006958 192.0
TLS2_k127_7020881_5 domain, Protein - - - 0.000000000000000000000000000000000000000000000000004593 204.0
TLS2_k127_7020881_6 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000000000000000000000001229 165.0
TLS2_k127_7020881_7 MgtC family K07507 - - 0.0000000000000000000000001577 111.0
TLS2_k127_7020881_8 FAD linked oxidase domain protein - - - 0.0000000000000000000004874 104.0
TLS2_k127_7020881_9 Belongs to the universal stress protein A family - - - 0.0000000000000000002 94.0
TLS2_k127_7027032_0 Tricorn protease homolog - - - 1.435e-276 869.0
TLS2_k127_7027032_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002194 294.0
TLS2_k127_7039907_0 Carboxypeptidase regulatory-like domain - - - 0.0 1120.0
TLS2_k127_7039907_1 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 612.0
TLS2_k127_7039907_10 peptidyl-tyrosine sulfation - - - 0.0002084 52.0
TLS2_k127_7039907_2 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 559.0
TLS2_k127_7039907_3 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K03778 - 1.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 439.0
TLS2_k127_7039907_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 413.0
TLS2_k127_7039907_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003887 266.0
TLS2_k127_7039907_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000008843 227.0
TLS2_k127_7039907_7 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000006626 199.0
TLS2_k127_7039907_8 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000001896 136.0
TLS2_k127_7039907_9 TPR repeat - - - 0.00001292 57.0
TLS2_k127_7051390_0 SIS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 316.0
TLS2_k127_7051390_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 315.0
TLS2_k127_7051390_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005289 274.0
TLS2_k127_7051390_3 Protein of unknown function (DUF433) - - - 0.00000000009183 68.0
TLS2_k127_7051390_4 Mut7-C RNAse domain - - - 0.000008338 49.0
TLS2_k127_7095087_0 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 340.0
TLS2_k127_7095087_1 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000003655 146.0
TLS2_k127_7095087_2 Belongs to the ompA family - - - 0.0000932 53.0
TLS2_k127_7105276_0 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000247 205.0
TLS2_k127_7105276_1 Transporter associated domain K03699 - - 0.00000000000000000000000000000004195 129.0
TLS2_k127_7154691_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.584e-213 677.0
TLS2_k127_7154691_1 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 577.0
TLS2_k127_7154691_10 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 337.0
TLS2_k127_7154691_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001788 304.0
TLS2_k127_7154691_12 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001786 267.0
TLS2_k127_7154691_13 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000006728 143.0
TLS2_k127_7154691_14 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000007995 130.0
TLS2_k127_7154691_15 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000001773 123.0
TLS2_k127_7154691_16 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000002784 90.0
TLS2_k127_7154691_17 Essential cell division protein K03589 - - 0.00000001349 67.0
TLS2_k127_7154691_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 495.0
TLS2_k127_7154691_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 485.0
TLS2_k127_7154691_4 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 453.0
TLS2_k127_7154691_5 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 441.0
TLS2_k127_7154691_6 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 445.0
TLS2_k127_7154691_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 416.0
TLS2_k127_7154691_8 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 356.0
TLS2_k127_7154691_9 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 348.0
TLS2_k127_7154963_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 549.0
TLS2_k127_7154963_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 560.0
TLS2_k127_7154963_10 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 375.0
TLS2_k127_7154963_11 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 377.0
TLS2_k127_7154963_12 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 372.0
TLS2_k127_7154963_13 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 360.0
TLS2_k127_7154963_14 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 350.0
TLS2_k127_7154963_15 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 310.0
TLS2_k127_7154963_16 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002249 268.0
TLS2_k127_7154963_17 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000004203 250.0
TLS2_k127_7154963_18 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000003375 218.0
TLS2_k127_7154963_19 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000001021 210.0
TLS2_k127_7154963_2 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 503.0
TLS2_k127_7154963_20 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000006445 214.0
TLS2_k127_7154963_21 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000001283 189.0
TLS2_k127_7154963_22 Stationary phase survival protein, YicC family, YicC_N and DUF1732 domain-containing - - - 0.000000000000000000000000000000000000000000000002332 192.0
TLS2_k127_7154963_23 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000006146 194.0
TLS2_k127_7154963_24 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000002101 165.0
TLS2_k127_7154963_25 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000163 158.0
TLS2_k127_7154963_26 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000001248 123.0
TLS2_k127_7154963_27 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000001266 128.0
TLS2_k127_7154963_28 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.0000000000000000000000001774 119.0
TLS2_k127_7154963_29 Regulatory protein - - - 0.00000000000000000002639 99.0
TLS2_k127_7154963_3 lipid A export permease ATP-binding protein MsbA K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 507.0
TLS2_k127_7154963_30 S-layer protein - - - 0.00000003072 66.0
TLS2_k127_7154963_31 methyltransferase - - - 0.000008623 55.0
TLS2_k127_7154963_32 Tetratricopeptide repeat - - - 0.000133 54.0
TLS2_k127_7154963_33 - - - - 0.0002345 49.0
TLS2_k127_7154963_4 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 472.0
TLS2_k127_7154963_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 471.0
TLS2_k127_7154963_6 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 425.0
TLS2_k127_7154963_7 Bacterial sugar transferase K03606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 420.0
TLS2_k127_7154963_8 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 400.0
TLS2_k127_7154963_9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 384.0
TLS2_k127_7163532_0 transport - - - 5.354e-284 912.0
TLS2_k127_7163532_1 heme-binding domain, Pirellula Verrucomicrobium type - - - 0.0000000000000000000000000006682 120.0
TLS2_k127_7166045_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 511.0
TLS2_k127_7166045_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 316.0
TLS2_k127_7166045_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000003217 198.0
TLS2_k127_7166045_3 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000649 68.0
TLS2_k127_7166045_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001147 67.0
TLS2_k127_7166045_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000575 67.0
TLS2_k127_7172389_0 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.0000000000000000000000000000000000000000000000000000009672 203.0
TLS2_k127_7172389_1 - - - - 0.0000000000000000000003048 104.0
TLS2_k127_7173463_0 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000007048 154.0
TLS2_k127_7173463_1 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000000000000000000003807 135.0
TLS2_k127_7174115_0 efflux transmembrane transporter activity - - - 1.697e-223 707.0
TLS2_k127_7185499_0 Gaf domain K01768,K11527,K18967,K21009 - 2.7.13.3,2.7.7.65,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000006902 219.0
TLS2_k127_7185499_1 Molecular chaperone. Has ATPase activity K04079 - - 0.0004773 52.0
TLS2_k127_7204106_1 PFAM glutamine amidotransferase class-I K07010 - - 0.0000000000000000000000000000000000000000000000000003873 195.0
TLS2_k127_7204106_2 protein-disulfide reductase activity - - - 0.00000000000001467 81.0
TLS2_k127_7204106_3 acyl-CoA dehydrogenase activity - - - 0.0009522 42.0
TLS2_k127_7233586_0 ribonucleoside-diphosphate reductase activity K00525 - 1.17.4.1 4.013e-296 923.0
TLS2_k127_7233586_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 317.0
TLS2_k127_7233586_2 DinB family - - - 0.00000000000000000000000000000000000000000000000000002047 192.0
TLS2_k127_7233586_3 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000001793 188.0
TLS2_k127_7233586_4 sigma factor activity K02405 - - 0.00000000000000000000000000000000009001 146.0
TLS2_k127_7233586_5 - - - - 0.00000000000000000000000000005299 134.0
TLS2_k127_7233586_6 CHAT domain - - - 0.0000000000000000000000000489 126.0
TLS2_k127_7233586_7 COG0457 FOG TPR repeat - - - 0.000000000000000000001754 98.0
TLS2_k127_7233586_8 PFAM AsmA family protein K07289 - - 0.000000000000000000002988 108.0
TLS2_k127_7241664_0 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 359.0
TLS2_k127_7241664_1 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001166 287.0
TLS2_k127_7241664_2 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.0000000000000000000000000000000000000000000000000000000000000000006828 229.0
TLS2_k127_7241664_5 Hemerythrin HHE cation binding domain - - - 0.0009392 49.0
TLS2_k127_7248755_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 461.0
TLS2_k127_7248755_1 Polysaccharide biosynthesis protein GumL K13665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 338.0
TLS2_k127_7248755_2 May be the GTPase, regulating ATP sulfurylase activity K00955 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009539 278.0
TLS2_k127_7248755_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000002216 243.0
TLS2_k127_7248755_4 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000001732 224.0
TLS2_k127_7248755_5 glycosyl transferase family 8 - - - 0.000000000000000003218 99.0
TLS2_k127_724906_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 3.898e-211 671.0
TLS2_k127_724906_1 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 617.0
TLS2_k127_724906_10 SnoaL-like domain - - - 0.000000000000000007528 91.0
TLS2_k127_724906_12 Hypothetical methyltransferase - - - 0.0000000006516 68.0
TLS2_k127_724906_14 HTH-like domain K07497 - - 0.0002547 45.0
TLS2_k127_724906_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 424.0
TLS2_k127_724906_3 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 355.0
TLS2_k127_724906_4 Oxidoreductase family, NAD-binding Rossmann fold K00118,K13020 - 1.1.1.335,1.1.99.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001878 293.0
TLS2_k127_724906_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000001527 218.0
TLS2_k127_724906_6 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000004067 207.0
TLS2_k127_724906_7 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000000000000000000001089 160.0
TLS2_k127_724906_8 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000006285 125.0
TLS2_k127_724906_9 PFAM transposase IS3 IS911 family protein K07483 - - 0.0000000000000000000000000534 110.0
TLS2_k127_727979_0 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000004337 205.0
TLS2_k127_727979_1 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000003954 100.0
TLS2_k127_727979_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000001197 87.0
TLS2_k127_727979_3 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215 - 0.000000000002463 79.0
TLS2_k127_727979_4 TonB C terminal K03832 - - 0.00004432 55.0
TLS2_k127_7305588_0 Type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000002496 214.0
TLS2_k127_7305588_1 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000001977 209.0
TLS2_k127_7305588_2 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000001034 196.0
TLS2_k127_7305588_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0005093 50.0
TLS2_k127_7323684_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 359.0
TLS2_k127_7323684_1 Cytochrome c - - - 0.000000000000000000000000000000000000002406 153.0
TLS2_k127_7323684_2 protein homotetramerization - - - 0.0000000000000000000000000002375 125.0
TLS2_k127_7323684_3 Tellurite resistance protein TehB - - - 0.0000000000004822 74.0
TLS2_k127_7323684_4 Protein of unknown function DUF86 - - - 0.00000002322 58.0
TLS2_k127_7390876_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 507.0
TLS2_k127_7390876_1 protein kinase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 491.0
TLS2_k127_7390876_10 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000001611 97.0
TLS2_k127_7390876_11 bacterial-type flagellum-dependent cell motility - - - 0.00000000000009033 85.0
TLS2_k127_7390876_12 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.000000000002021 73.0
TLS2_k127_7390876_13 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000023 59.0
TLS2_k127_7390876_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 466.0
TLS2_k127_7390876_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 451.0
TLS2_k127_7390876_4 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 467.0
TLS2_k127_7390876_5 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 424.0
TLS2_k127_7390876_6 - K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 421.0
TLS2_k127_7390876_7 protein kinase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 299.0
TLS2_k127_7390876_8 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006416 274.0
TLS2_k127_7390876_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000007691 201.0
TLS2_k127_7429484_0 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001656 265.0
TLS2_k127_7429484_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000582 207.0
TLS2_k127_7429484_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000005795 113.0
TLS2_k127_7445186_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 369.0
TLS2_k127_7445186_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 317.0
TLS2_k127_7445186_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000001092 121.0
TLS2_k127_7445591_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 425.0
TLS2_k127_7445591_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 289.0
TLS2_k127_7445591_10 Phosphotransferase System K11189 - - 0.000000000000000005415 87.0
TLS2_k127_7445591_11 Outer membrane lipoprotein - - - 0.00000000000000001433 94.0
TLS2_k127_7445591_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000331 289.0
TLS2_k127_7445591_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000007091 238.0
TLS2_k127_7445591_4 WD40-like Beta Propeller K03641 - - 0.000000000000000000000000000000000000000000000000000008222 198.0
TLS2_k127_7445591_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000033 172.0
TLS2_k127_7445591_6 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000004908 170.0
TLS2_k127_7445591_7 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000001824 148.0
TLS2_k127_7445591_8 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000002096 118.0
TLS2_k127_7445591_9 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.000000000000000000000000007647 115.0
TLS2_k127_745941_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 559.0
TLS2_k127_745941_1 Fe-S oxidoreductase K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 509.0
TLS2_k127_745941_2 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 373.0
TLS2_k127_745941_3 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 329.0
TLS2_k127_745941_4 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000001106 248.0
TLS2_k127_745941_5 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000000000000000000000005535 213.0
TLS2_k127_745941_6 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000003195 180.0
TLS2_k127_745941_7 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.000000000000000000000007913 110.0
TLS2_k127_745941_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000003702 84.0
TLS2_k127_7466098_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003892 249.0
TLS2_k127_7466098_1 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000001927 213.0
TLS2_k127_752595_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.515e-231 736.0
TLS2_k127_752595_1 transport system periplasmic component K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 377.0
TLS2_k127_752595_2 aldo keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 363.0
TLS2_k127_752595_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000005267 192.0
TLS2_k127_752595_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000002407 177.0
TLS2_k127_752595_5 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000000000000002541 187.0
TLS2_k127_752595_6 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000002543 107.0
TLS2_k127_752595_7 Phospholipid methyltransferase - - - 0.0000000000000000000004402 106.0
TLS2_k127_754703_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000001533 196.0
TLS2_k127_754703_1 TonB-dependent receptor - - - 0.0000000000000000000004872 106.0
TLS2_k127_76797_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 4.587e-250 799.0
TLS2_k127_76797_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 5.487e-233 728.0
TLS2_k127_76797_2 PFAM Radical SAM - - - 3.192e-228 717.0
TLS2_k127_76797_3 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 440.0
TLS2_k127_76797_4 Na+/Pi-cotransporter K14683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002106 291.0
TLS2_k127_76797_5 - - - - 0.00000000000000000000000000000000000000000000000007393 185.0
TLS2_k127_76797_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000002478 106.0
TLS2_k127_76797_7 PhoU domain - - - 0.00000000000000002185 96.0
TLS2_k127_76797_8 monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.000000002875 59.0
TLS2_k127_825676_0 Asparagine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 512.0
TLS2_k127_825676_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000007224 143.0
TLS2_k127_825676_2 Protein of unknown function (DUF1698) - - - 0.000000000000000000000000000002026 137.0
TLS2_k127_825676_3 Glycosyl transferase - - - 0.000000000000000005848 98.0
TLS2_k127_82899_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 496.0
TLS2_k127_82899_1 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 385.0
TLS2_k127_82899_2 phosphatidylcholine synthase K01004 - 2.7.8.24 0.00000000000000000000000000000000000000000000000000000007772 206.0
TLS2_k127_82899_3 - - - - 0.00000000000000002949 83.0
TLS2_k127_836318_0 thiamine-containing compound biosynthetic process K02051 - - 1.3e-206 655.0
TLS2_k127_836318_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 404.0
TLS2_k127_836318_2 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 363.0
TLS2_k127_836318_3 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 345.0
TLS2_k127_836318_4 tRNA synthetases class I (E and Q), catalytic domain K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 304.0
TLS2_k127_836318_5 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 287.0
TLS2_k127_836318_6 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000002188 229.0
TLS2_k127_836318_7 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000005632 141.0
TLS2_k127_836318_8 Outer membrane protein, OMP85 family K07277 - - 0.0000000000006016 83.0
TLS2_k127_836318_9 PFAM von Willebrand factor type A K07114 - - 0.000001925 58.0
TLS2_k127_839959_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1062.0
TLS2_k127_839959_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 467.0
TLS2_k127_839959_2 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 419.0
TLS2_k127_839959_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 343.0
TLS2_k127_839959_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000005567 136.0
TLS2_k127_894288_0 ATPase with chaperone activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 370.0
TLS2_k127_894288_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000007738 203.0
TLS2_k127_894288_2 PFAM von Willebrand factor type A - - - 0.00000000000000000000000002617 126.0
TLS2_k127_894288_3 von Willebrand factor type A domain - - - 0.000000000001559 81.0
TLS2_k127_894288_4 Type II secretion system K12511 - - 0.00000000009453 63.0
TLS2_k127_894288_5 FOG TPR repeat - - - 0.0004875 51.0
TLS2_k127_90291_0 carboxylic acid catabolic process K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000001944 246.0
TLS2_k127_90291_1 carboxylic acid catabolic process K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000001525 165.0
TLS2_k127_910811_0 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 306.0
TLS2_k127_910811_1 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000009282 192.0
TLS2_k127_910811_2 Belongs to the UPF0061 (SELO) family K08997 - - 0.000000000000000000000000000000004574 133.0
TLS2_k127_910811_3 - - - - 0.00000000000000000000000000000004846 127.0
TLS2_k127_910811_4 Sporulation related domain K03749 - - 0.00007541 53.0
TLS2_k127_940135_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 299.0
TLS2_k127_940135_1 PFAM Stage II sporulation protein E (SpoIIE) - - - 0.0000000000000000000000000000000000000000007935 166.0
TLS2_k127_944916_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 592.0
TLS2_k127_944916_1 Pfam:DUF303 K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 445.0
TLS2_k127_944916_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000001379 174.0
TLS2_k127_944916_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000004934 101.0
TLS2_k127_944916_4 - - - - 0.000000000000362 80.0