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Overview

ID MAG04033
Name TLS3_bin.1
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Limnocylindria
Order Limnocylindrales
Family CSP1-4
Genus JAFMJV01
Species
Assembly information
Completeness (%) 66.0
Contamination (%) 2.28
GC content (%) 72.0
N50 (bp) 7,125
Genome size (bp) 2,817,710

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2523

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1049227_0 Extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 387.0
TLS3_k127_1049227_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000132 259.0
TLS3_k127_1049227_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000003398 97.0
TLS3_k127_1049227_3 toxin-antitoxin pair type II binding - - - 0.0000000000002325 72.0
TLS3_k127_1052620_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 604.0
TLS3_k127_1052620_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000004161 148.0
TLS3_k127_1052620_3 Diacylglycerol kinase K19302 - 3.6.1.27 0.00000000000000000000000000001219 130.0
TLS3_k127_1052620_4 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000001293 132.0
TLS3_k127_1052620_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000005749 85.0
TLS3_k127_1052620_6 Copper binding proteins, plastocyanin/azurin family - - - 0.0000002761 60.0
TLS3_k127_1052620_7 AI-2E family transporter - - - 0.00004906 56.0
TLS3_k127_1075058_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 446.0
TLS3_k127_1075058_1 ABC transporter (Permease) K02025,K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 405.0
TLS3_k127_1075058_2 Binding-protein-dependent transport systems inner membrane component K02026,K10202 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 382.0
TLS3_k127_1075058_3 C-5 cytosine-specific DNA methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 366.0
TLS3_k127_1075058_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000004052 215.0
TLS3_k127_1075058_5 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000003495 180.0
TLS3_k127_1075058_6 lipoyl(octanoyl) transferase activity K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.000000000000000000000000000000000000000000005056 174.0
TLS3_k127_1075058_7 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000001688 157.0
TLS3_k127_1075058_8 tRNA methyltransferase activity K00558 - 2.1.1.37 0.000000004148 70.0
TLS3_k127_1075821_0 inositol 2-dehydrogenase activity K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001305 277.0
TLS3_k127_1075821_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000002138 168.0
TLS3_k127_1116566_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 379.0
TLS3_k127_1116566_1 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006866 256.0
TLS3_k127_1116566_2 UTRA K03710 - - 0.000000000000000000000000000000000000000000000004167 183.0
TLS3_k127_1116566_3 sugar isomerase - - - 0.0000000000000000000000000000003381 126.0
TLS3_k127_1116566_4 COG1175 ABC-type sugar transport systems permease components K02025 - - 0.000000000001666 68.0
TLS3_k127_1143069_0 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 492.0
TLS3_k127_1143069_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 348.0
TLS3_k127_1143069_10 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000002535 85.0
TLS3_k127_1143069_11 Dodecin K09165 - - 0.00000000004284 65.0
TLS3_k127_1143069_12 Protein of unknown function (DUF1232) - - - 0.000000004095 65.0
TLS3_k127_1143069_13 acetyltransferase - - - 0.0000001978 62.0
TLS3_k127_1143069_2 TIGRFAM glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001904 267.0
TLS3_k127_1143069_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000001268 246.0
TLS3_k127_1143069_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000003185 190.0
TLS3_k127_1143069_5 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000004291 138.0
TLS3_k127_1143069_6 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000001341 140.0
TLS3_k127_1143069_7 domain protein K03709 - - 0.000000000000000000000000000000951 135.0
TLS3_k127_1143069_8 trisaccharide binding K03556 - - 0.0000000000000000000000000004713 132.0
TLS3_k127_1143069_9 Formiminotransferase-cyclodeaminase K01746 - 4.3.1.4 0.00000000000000000002289 100.0
TLS3_k127_114813_0 AAA ATPase domain - - - 2.161e-209 660.0
TLS3_k127_114813_1 PFAM Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000000000001253 232.0
TLS3_k127_114813_2 GYD domain - - - 0.00000000000000000000000000000000000000000000000014 179.0
TLS3_k127_114813_3 glyoxalase III activity K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000001125 167.0
TLS3_k127_114813_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000005166 109.0
TLS3_k127_114813_5 Nucleoside 2-deoxyribosyltransferase - - - 0.000000000000000003052 90.0
TLS3_k127_114813_6 SnoaL-like polyketide cyclase - - - 0.00000000005579 69.0
TLS3_k127_114813_7 - - - - 0.0000000009889 66.0
TLS3_k127_1166932_0 PFAM response regulator receiver K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 351.0
TLS3_k127_1166932_1 Type II/IV secretion system protein K02283 - - 0.00000002863 58.0
TLS3_k127_1166932_2 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000003305 61.0
TLS3_k127_1166932_3 Flp/Fap pilin component K02651 - - 0.000003686 51.0
TLS3_k127_1166932_4 Flp/Fap pilin component K02651 - - 0.0004226 45.0
TLS3_k127_1191858_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 6.754e-194 620.0
TLS3_k127_1191858_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 402.0
TLS3_k127_1191858_2 SIS domain K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 341.0
TLS3_k127_1191858_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 317.0
TLS3_k127_1191858_4 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000005596 275.0
TLS3_k127_1218039_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 1.877e-213 678.0
TLS3_k127_1218039_1 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 387.0
TLS3_k127_1218039_2 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 330.0
TLS3_k127_1218039_3 Periplasmic binding protein-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 314.0
TLS3_k127_1218039_4 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0000000000002621 74.0
TLS3_k127_1218039_5 - - - - 0.0000007014 52.0
TLS3_k127_1218039_6 anthranilate synthase K13063 - 2.6.1.86 0.0008038 46.0
TLS3_k127_1219501_0 UDP-glucoronosyl and UDP-glucosyl transferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0020012,GO:0030682,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 4.507e-207 651.0
TLS3_k127_1219501_1 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 425.0
TLS3_k127_1219501_2 TOBE domain K11072,K11076 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 424.0
TLS3_k127_1219501_3 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001082 285.0
TLS3_k127_1219501_4 nuclease activity K18828 - - 0.0000007428 58.0
TLS3_k127_1219741_0 FAD linked oxidases, C-terminal domain - - - 4.021e-279 890.0
TLS3_k127_1219741_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 452.0
TLS3_k127_1219741_10 Periplasmic binding protein domain K02058 - - 0.000000000000000000003801 107.0
TLS3_k127_1219741_11 L-rhamnose mutarotase K03534 - 5.1.3.32 0.00000000000000001048 93.0
TLS3_k127_1219741_12 L-rhamnose mutarotase K03534 - 5.1.3.32 0.0000000000000002951 88.0
TLS3_k127_1219741_13 Involved in the anomeric conversion of L-rhamnose K03534 - 5.1.3.32 0.00000000000003469 84.0
TLS3_k127_1219741_14 Transcriptional regulator K13652 - - 0.000000006718 68.0
TLS3_k127_1219741_15 Major facilitator Superfamily - - - 0.00000001289 68.0
TLS3_k127_1219741_2 Aldo keto reductase K00064 - 1.1.1.122 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 378.0
TLS3_k127_1219741_3 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001469 291.0
TLS3_k127_1219741_4 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K07404 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003997 278.0
TLS3_k127_1219741_5 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005926 239.0
TLS3_k127_1219741_6 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000002805 225.0
TLS3_k127_1219741_7 Alcohol dehydrogenase zinc-binding domain protein K13953,K18382 - 1.1.1.1 0.0000000000000000000000000000000000000000000228 173.0
TLS3_k127_1219741_8 Lipocalin-like domain - - - 0.0000000000000000000000000002114 126.0
TLS3_k127_1219741_9 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.000000000000000000001394 110.0
TLS3_k127_122990_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 377.0
TLS3_k127_122990_10 Zincin-like metallopeptidase - - - 0.000000000000000000000000001232 117.0
TLS3_k127_122990_12 Alpha beta hydrolase - - - 0.00000000004224 75.0
TLS3_k127_122990_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0001222 46.0
TLS3_k127_122990_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003663 270.0
TLS3_k127_122990_3 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000253 254.0
TLS3_k127_122990_4 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000001305 232.0
TLS3_k127_122990_5 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000001489 223.0
TLS3_k127_122990_6 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000003926 190.0
TLS3_k127_122990_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000003021 187.0
TLS3_k127_122990_8 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000001083 162.0
TLS3_k127_122990_9 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000329 162.0
TLS3_k127_1251632_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 419.0
TLS3_k127_1251632_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 384.0
TLS3_k127_1251632_2 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000008238 237.0
TLS3_k127_1251632_3 Uncharacterised protein family UPF0047 - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000001576 181.0
TLS3_k127_1251632_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000004576 196.0
TLS3_k127_1251632_5 Belongs to the UPF0235 family K09131 - - 0.00000000000003497 80.0
TLS3_k127_1251632_6 YGGT family K02221 - - 0.0000000000001323 76.0
TLS3_k127_1251632_7 LysM domain - - - 0.0000000000002136 82.0
TLS3_k127_1251632_8 Cell division protein FtsQ K03589 - - 0.00000004055 62.0
TLS3_k127_1251632_9 polygalacturonase activity - - - 0.0001093 53.0
TLS3_k127_1296907_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 289.0
TLS3_k127_1296907_1 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000000000000000000000000006037 209.0
TLS3_k127_1296907_2 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000006441 125.0
TLS3_k127_1318254_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 4.997e-203 646.0
TLS3_k127_1318254_1 Pyridoxal-phosphate dependent enzyme K01697 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 4.2.1.22 0.0000000000005641 72.0
TLS3_k127_1335495_0 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000001206 149.0
TLS3_k127_1335495_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.00000000000000000000000000000001172 136.0
TLS3_k127_1377585_0 helicase superfamily c-terminal domain K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 499.0
TLS3_k127_1377585_1 OsmC-like protein - - - 0.000000000000000000000000000000000008089 142.0
TLS3_k127_1380581_0 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000009937 262.0
TLS3_k127_1380581_1 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000004894 201.0
TLS3_k127_1380581_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000002338 196.0
TLS3_k127_1380581_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000001024 153.0
TLS3_k127_1380581_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000001823 124.0
TLS3_k127_1380581_5 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000007599 68.0
TLS3_k127_1383702_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 609.0
TLS3_k127_1383702_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 411.0
TLS3_k127_1383702_2 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000003513 188.0
TLS3_k127_1383702_3 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02034 - - 0.000000000000000000006835 94.0
TLS3_k127_1385069_0 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000001957 160.0
TLS3_k127_1385069_1 Acyltransferase family - - - 0.00000000000000000000000000000004106 134.0
TLS3_k127_1419616_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 0.0 1057.0
TLS3_k127_1419616_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000389 259.0
TLS3_k127_1419616_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000004472 177.0
TLS3_k127_1419616_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000002053 98.0
TLS3_k127_1419616_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0009099 51.0
TLS3_k127_1431484_0 Xylulose kinase K00854 - 2.7.1.17 2.15e-196 638.0
TLS3_k127_1431484_1 ABC-type sugar transport system, permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 473.0
TLS3_k127_1431484_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 458.0
TLS3_k127_1431484_3 M42 glutamyl aminopeptidase K20609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 403.0
TLS3_k127_1431484_4 BtpA family K06971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 403.0
TLS3_k127_1431484_5 ABC transporter substrate-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 331.0
TLS3_k127_1431484_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 323.0
TLS3_k127_1431484_7 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008876 290.0
TLS3_k127_1431484_8 SIS domain K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000254 192.0
TLS3_k127_1431484_9 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000002497 160.0
TLS3_k127_1450104_0 DNA primase, small subunit K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 615.0
TLS3_k127_1450104_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000009213 181.0
TLS3_k127_1450104_2 Nitroreductase family - - - 0.000000000000000000000000000000000001477 147.0
TLS3_k127_1450104_3 Protein of unknown function (DUF3307) - - - 0.00000000000000000102 96.0
TLS3_k127_1450104_4 - - - - 0.0007293 52.0
TLS3_k127_1466784_0 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 426.0
TLS3_k127_1466784_1 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005215 271.0
TLS3_k127_1473030_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 580.0
TLS3_k127_1473030_1 (ABC) transporter - - - 0.00000416 59.0
TLS3_k127_1473485_0 PFAM ABC transporter related K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 356.0
TLS3_k127_1473485_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000001123 138.0
TLS3_k127_1473485_2 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.0000000000000000000000000000001839 139.0
TLS3_k127_1497775_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01537,K12952 - 3.6.3.2,3.6.3.8 6.806e-209 678.0
TLS3_k127_1497775_1 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 316.0
TLS3_k127_1497775_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000003499 112.0
TLS3_k127_1562605_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000005867 246.0
TLS3_k127_1562605_1 Helix-turn-helix type 11 domain protein K13572 - - 0.000000000000000000000000000000000000000000000006547 183.0
TLS3_k127_1562605_2 diguanylate cyclase - - - 0.00000000000000000000000000000000002682 154.0
TLS3_k127_1562605_3 Aminoacyl-tRNA editing domain - - - 0.0000000000002549 72.0
TLS3_k127_1603011_0 DEAD/H associated K03724 - - 0.0 1497.0
TLS3_k127_1603011_1 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 579.0
TLS3_k127_1603011_2 Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 422.0
TLS3_k127_1603011_3 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 347.0
TLS3_k127_1603011_4 acetoin utilization protein K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 319.0
TLS3_k127_1603011_5 Belongs to the FPG family K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000001162 224.0
TLS3_k127_1603011_6 RmlD substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002234 231.0
TLS3_k127_1603011_7 Haloacid dehalogenase-like hydrolase K19270 - 3.1.3.23 0.00000000000000000000000000000000000001801 147.0
TLS3_k127_1603011_9 protein with SCP PR1 domains - - - 0.0000000000000000007236 97.0
TLS3_k127_1617711_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 502.0
TLS3_k127_1625703_0 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000000000000000000000004032 131.0
TLS3_k127_1625703_1 PAS fold - - - 0.00000000000001843 85.0
TLS3_k127_1625703_2 - - - - 0.00000973 53.0
TLS3_k127_1629553_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000002157 187.0
TLS3_k127_1629553_1 PFAM PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000682 157.0
TLS3_k127_1640908_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 473.0
TLS3_k127_1640908_1 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 411.0
TLS3_k127_1640908_2 Monosaccharide ABC transporter ATP-binding protein, CUT2 family K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 373.0
TLS3_k127_1640908_3 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000951 135.0
TLS3_k127_1640908_4 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000005289 111.0
TLS3_k127_1640908_5 Belongs to the UPF0109 family K06960 - - 0.000000000000000001677 87.0
TLS3_k127_1640908_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000005648 94.0
TLS3_k127_1714864_0 alpha-galactosidase K07407 - 3.2.1.22 1.421e-208 664.0
TLS3_k127_1714864_1 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 378.0
TLS3_k127_1728833_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 337.0
TLS3_k127_1728833_1 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000002035 185.0
TLS3_k127_1728833_2 Pfam:DUF385 - - - 0.00000000000000002255 88.0
TLS3_k127_174767_0 COG0608 Single-stranded DNA-specific exonuclease K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 315.0
TLS3_k127_174767_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003596 279.0
TLS3_k127_174767_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000006837 196.0
TLS3_k127_174767_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000002344 70.0
TLS3_k127_1778130_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 486.0
TLS3_k127_1778130_1 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 468.0
TLS3_k127_1778130_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 338.0
TLS3_k127_1778130_3 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001026 257.0
TLS3_k127_1778130_4 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000001038 147.0
TLS3_k127_1778130_5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000008751 115.0
TLS3_k127_1778130_6 serine threonine protein kinase - - - 0.000000000000000000000002551 106.0
TLS3_k127_1797492_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 539.0
TLS3_k127_1797492_1 ATPases associated with a variety of cellular activities K10112,K10195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 448.0
TLS3_k127_1797492_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.000000000000000000000000000000000000000000000002339 189.0
TLS3_k127_1797492_3 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000003376 179.0
TLS3_k127_1797492_4 Lamin Tail Domain K07004 - - 0.000002507 59.0
TLS3_k127_1811390_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.703e-195 636.0
TLS3_k127_1811390_1 ATPase with chaperone activity K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 407.0
TLS3_k127_1811390_10 - - - - 0.000019 51.0
TLS3_k127_1811390_2 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 316.0
TLS3_k127_1811390_3 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002081 276.0
TLS3_k127_1811390_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000001072 247.0
TLS3_k127_1811390_5 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000862 236.0
TLS3_k127_1811390_6 PFAM response regulator receiver K02282 - - 0.00000000000000000000000000000000000000000000000000000000004773 220.0
TLS3_k127_1811390_7 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000007918 175.0
TLS3_k127_1811390_8 MutT family - - - 0.00000000000000000000000000006755 121.0
TLS3_k127_1811390_9 Methicillin resistance protein - - - 0.0000000203 68.0
TLS3_k127_1815825_0 Sodium:sulfate symporter transmembrane region - - - 3.084e-209 666.0
TLS3_k127_1815825_1 Transporter K12942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 537.0
TLS3_k127_1815825_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 497.0
TLS3_k127_1815825_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 419.0
TLS3_k127_1815825_4 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 377.0
TLS3_k127_1815825_5 gntR family K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000006996 237.0
TLS3_k127_1815825_6 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000253 148.0
TLS3_k127_1852182_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 2.595e-220 711.0
TLS3_k127_1852182_1 protein conserved in bacteria - - - 3.892e-206 655.0
TLS3_k127_1852182_2 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 582.0
TLS3_k127_1852182_3 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 484.0
TLS3_k127_1852182_4 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000001338 174.0
TLS3_k127_1852182_5 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000002171 78.0
TLS3_k127_1862253_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 540.0
TLS3_k127_1879106_0 Rieske 2Fe-2S - - - 0.0000000000000000000000000006745 121.0
TLS3_k127_1879106_1 Copper-binding protein - - - 0.00001596 57.0
TLS3_k127_1879106_2 protein ubiquitination K10444,K10461,K13959 GO:0000151,GO:0000976,GO:0001067,GO:0002250,GO:0002253,GO:0002376,GO:0002429,GO:0002460,GO:0002467,GO:0002682,GO:0002684,GO:0002757,GO:0002764,GO:0002768,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005911,GO:0005912,GO:0006355,GO:0006357,GO:0006464,GO:0006807,GO:0006955,GO:0006996,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0009653,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016567,GO:0019219,GO:0019222,GO:0019538,GO:0023052,GO:0030054,GO:0030057,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031461,GO:0031463,GO:0032446,GO:0032502,GO:0032991,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0045103,GO:0045104,GO:0045109,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048646,GO:0048856,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050851,GO:0050853,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0051865,GO:0060255,GO:0065007,GO:0070161,GO:0070647,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0097435,GO:0140110,GO:1901363,GO:1901564,GO:1902494,GO:1902680,GO:1903506,GO:1903508,GO:1990234,GO:1990837,GO:2000112,GO:2001141 - 0.0003605 50.0
TLS3_k127_1921495_0 ABC transporter substrate-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001258 289.0
TLS3_k127_1921495_1 Belongs to the ABC transporter superfamily K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003287 245.0
TLS3_k127_1939595_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 351.0
TLS3_k127_1939595_1 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000004801 215.0
TLS3_k127_1939595_2 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000000000000006645 205.0
TLS3_k127_1939595_3 alpha/beta hydrolase fold - GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000004042 181.0
TLS3_k127_1939595_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000007718 164.0
TLS3_k127_1939595_5 domain, Protein - - - 0.0000000000000003577 88.0
TLS3_k127_1939595_6 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000006879 60.0
TLS3_k127_1939595_7 glyoxalase III activity - - - 0.0000009689 59.0
TLS3_k127_196874_0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 453.0
TLS3_k127_196874_1 Creatinase/Prolidase N-terminal domain K01271,K01274 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 295.0
TLS3_k127_1974993_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 5.978e-216 702.0
TLS3_k127_1974993_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 397.0
TLS3_k127_1974993_10 Acyltransferase - - - 0.00000000000000000000000000000000000000001469 168.0
TLS3_k127_1974993_11 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000001758 153.0
TLS3_k127_1974993_12 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000001168 128.0
TLS3_k127_1974993_13 Acyltransferase family - - - 0.00000000000000000000000000009894 132.0
TLS3_k127_1974993_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000009748 109.0
TLS3_k127_1974993_15 DNA mismatch repair protein MutT - - - 0.00000000000000000000001168 110.0
TLS3_k127_1974993_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.0000000000000000004706 97.0
TLS3_k127_1974993_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000005943 91.0
TLS3_k127_1974993_18 Protein of unknown function (DUF3289) - - - 0.000000000000001566 90.0
TLS3_k127_1974993_19 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K05578 - 1.6.5.3 0.000000000000002559 85.0
TLS3_k127_1974993_2 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 389.0
TLS3_k127_1974993_20 GTP binding - - - 0.000000000000003882 87.0
TLS3_k127_1974993_21 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00127 - - 0.0000000000004042 83.0
TLS3_k127_1974993_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000007151 72.0
TLS3_k127_1974993_24 - K14645 - - 0.000828 50.0
TLS3_k127_1974993_3 NADH dehydrogenase K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 371.0
TLS3_k127_1974993_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 350.0
TLS3_k127_1974993_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002642 286.0
TLS3_k127_1974993_6 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007179 285.0
TLS3_k127_1974993_7 NADH dehydrogenase K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000005081 273.0
TLS3_k127_1974993_8 L11 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000001017 214.0
TLS3_k127_1974993_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000005386 193.0
TLS3_k127_2003961_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18983,K20023 - 4.2.1.156,4.2.1.42,5.5.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 306.0
TLS3_k127_2003961_1 Pro-kumamolisin, activation domain - - - 0.000000000000000000000000000000000000000000000000000000000001669 230.0
TLS3_k127_2003961_2 Protease prsW family - - - 0.00000000000000000000000000000004989 145.0
TLS3_k127_2003961_3 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000003776 101.0
TLS3_k127_2027975_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 335.0
TLS3_k127_2027975_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 291.0
TLS3_k127_2027975_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 294.0
TLS3_k127_2027975_3 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003183 276.0
TLS3_k127_2027975_4 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001171 251.0
TLS3_k127_2027975_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000001052 141.0
TLS3_k127_2035662_0 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 345.0
TLS3_k127_2035662_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001454 281.0
TLS3_k127_2035662_2 Capsule synthesis protein, CapA K07282 - - 0.0000000000000000000000000000000000000000000000000000005679 216.0
TLS3_k127_2035662_3 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000002344 121.0
TLS3_k127_2039777_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.353e-272 852.0
TLS3_k127_2039777_1 - - - - 0.000000000000000000000000000000000000003267 157.0
TLS3_k127_2039777_2 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000038 84.0
TLS3_k127_2039777_3 - - - - 0.0000000001151 72.0
TLS3_k127_2039777_4 Domain of unknown function (DUF4383) - - - 0.0000007481 61.0
TLS3_k127_2043483_0 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 536.0
TLS3_k127_2043483_1 Peptidase family M50 - - - 0.00000000000000000000002412 116.0
TLS3_k127_2043483_2 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000004786 83.0
TLS3_k127_2043483_3 Protein of unknown function (DUF1461) - - - 0.000004589 57.0
TLS3_k127_2044965_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 341.0
TLS3_k127_2044965_1 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000002302 225.0
TLS3_k127_2044965_2 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000005373 193.0
TLS3_k127_2044965_3 Pfam:Y_phosphatase3C K01104 - 3.1.3.48 0.0000000000000000000000000000000000000001193 159.0
TLS3_k127_2044965_4 - - - - 0.00001316 53.0
TLS3_k127_2053416_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001557 278.0
TLS3_k127_2053416_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003426 259.0
TLS3_k127_2053416_2 Belongs to the ABC transporter superfamily K02031,K02032 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000002308 183.0
TLS3_k127_2055778_0 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 535.0
TLS3_k127_2055778_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000004012 224.0
TLS3_k127_2055778_2 Cold shock K03704 - - 0.00001999 53.0
TLS3_k127_2076952_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 544.0
TLS3_k127_2076952_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006037 247.0
TLS3_k127_2076952_2 Probable zinc-ribbon domain - - - 0.00000000000000000000000000001159 125.0
TLS3_k127_2076952_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000005747 99.0
TLS3_k127_2076952_4 Calcineurin-like phosphoesterase K03547 - - 0.0000000000000494 82.0
TLS3_k127_2077012_0 helicase superfamily c-terminal domain K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000009273 180.0
TLS3_k127_2077012_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000001061 164.0
TLS3_k127_2077012_2 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.00000000000000000000000000006968 124.0
TLS3_k127_2077012_3 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000008276 122.0
TLS3_k127_2077012_4 negative regulation of DNA recombination - - - 0.0000000000000001634 86.0
TLS3_k127_2077012_5 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000004069 74.0
TLS3_k127_2086647_0 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 388.0
TLS3_k127_2086647_1 endonuclease III - - - 0.0000000000000000000000000000000000000000000000000000001359 199.0
TLS3_k127_2086647_2 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000123 86.0
TLS3_k127_2095548_0 major facilitator superfamily - - - 3.247e-224 707.0
TLS3_k127_2095548_1 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 316.0
TLS3_k127_2095548_2 Amidinotransferase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000002582 174.0
TLS3_k127_2095548_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000006339 56.0
TLS3_k127_2111588_0 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 478.0
TLS3_k127_2111588_1 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 380.0
TLS3_k127_2111588_2 PFAM binding-protein-dependent transport systems inner membrane component K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 311.0
TLS3_k127_2111588_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001537 239.0
TLS3_k127_2111588_4 PFAM binding-protein-dependent transport systems inner membrane component K15771 - - 0.00000000000000000000000000000000000000000000000003987 182.0
TLS3_k127_2111588_5 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000005466 190.0
TLS3_k127_2111588_6 MOSC N-terminal beta barrel domain - - - 0.000000000000000000000000000000000000000000006254 173.0
TLS3_k127_2120996_0 AAA domain - - - 0.000000000000000000000000000000000000000000000001464 186.0
TLS3_k127_2120996_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000003822 185.0
TLS3_k127_2120996_2 Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding - - - 0.00000000000000000001175 101.0
TLS3_k127_2120996_3 - - - - 0.000000000005462 75.0
TLS3_k127_2120996_4 Type VI secretion system VasI, EvfG, VC_A0118 - - - 0.000003606 58.0
TLS3_k127_2135973_0 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 330.0
TLS3_k127_2135973_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003136 293.0
TLS3_k127_2135973_10 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000772 98.0
TLS3_k127_2135973_11 Extracellular solute-binding protein K02027,K10236 - - 0.0000000000003339 82.0
TLS3_k127_2135973_12 BNR Asp-box repeat K01186 - 3.2.1.18 0.00001103 58.0
TLS3_k127_2135973_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002847 262.0
TLS3_k127_2135973_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000461 263.0
TLS3_k127_2135973_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000006237 248.0
TLS3_k127_2135973_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000004319 249.0
TLS3_k127_2135973_6 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K16422 - 1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000005296 238.0
TLS3_k127_2135973_7 PFAM oxidoreductase K18067 - 1.3.1.64 0.000000000000000000000000000000000000000000000000000000000002925 225.0
TLS3_k127_2135973_8 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.00000000000000000000000000000000000000000000008446 191.0
TLS3_k127_2135973_9 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000001265 115.0
TLS3_k127_216707_0 Helix-turn-helix domain, rpiR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 332.0
TLS3_k127_216707_1 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0000000001811 73.0
TLS3_k127_216707_2 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0000001195 63.0
TLS3_k127_2203623_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000005134 201.0
TLS3_k127_2204156_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000001743 139.0
TLS3_k127_2204156_1 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000001192 121.0
TLS3_k127_2242216_0 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 365.0
TLS3_k127_2242216_1 Protein of unknown function (DUF2568) - - - 0.0000000002256 72.0
TLS3_k127_2252891_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 503.0
TLS3_k127_2252891_1 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000001444 239.0
TLS3_k127_2252891_2 ATPase activity K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000007847 210.0
TLS3_k127_2252891_3 Cobalt transport protein K02008,K16785 - - 0.00000000000000000000000000000000000000000004501 171.0
TLS3_k127_2252891_4 ABC transporter substrate-binding protein PnrA-like - - - 0.00000000000000000000000657 111.0
TLS3_k127_2252891_5 phosphorelay sensor kinase activity K16923,K18967 - 2.7.7.65 0.00000000000000000000001886 107.0
TLS3_k127_2277819_0 gluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 335.0
TLS3_k127_2277819_1 alcohol dehydrogenase K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 319.0
TLS3_k127_2277819_2 Ribonuclease K01167 - 3.1.27.3 0.00000000000000000000000000000000000753 143.0
TLS3_k127_2277819_3 Histidine kinase - - - 0.0000000000000000000000000000000005416 152.0
TLS3_k127_2277819_4 Barstar (barnase inhibitor) - - - 0.000000000000002229 86.0
TLS3_k127_2303266_0 ABC transporter K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 344.0
TLS3_k127_2303266_1 Citrate synthase, C-terminal domain K01647,K01659 - 2.3.3.1,2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000003889 252.0
TLS3_k127_2315944_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1021.0
TLS3_k127_2315944_1 EamA-like transporter family - - - 0.000004706 51.0
TLS3_k127_2348482_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.99e-242 777.0
TLS3_k127_2348482_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 331.0
TLS3_k127_2348482_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 329.0
TLS3_k127_2348482_3 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000000011 113.0
TLS3_k127_2348482_4 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000001182 93.0
TLS3_k127_2348482_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000001917 56.0
TLS3_k127_2352223_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 291.0
TLS3_k127_2352223_1 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000001749 269.0
TLS3_k127_2352223_2 Belongs to the Orn Lys Arg decarboxylase class-II family K01586 - 4.1.1.20 0.0000000000000000000002145 112.0
TLS3_k127_235287_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1343.0
TLS3_k127_235287_1 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 574.0
TLS3_k127_235287_2 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 329.0
TLS3_k127_235287_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 319.0
TLS3_k127_235287_4 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006834 248.0
TLS3_k127_235287_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000001879 238.0
TLS3_k127_235287_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006059 232.0
TLS3_k127_235287_7 - - - - 0.0000000000000000000003249 104.0
TLS3_k127_235287_8 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000003847 53.0
TLS3_k127_235287_9 HupF/HypC family K04653 - - 0.0003277 47.0
TLS3_k127_2393975_0 ATPase family associated with various cellular activities (AAA) - - - 1.162e-205 671.0
TLS3_k127_2393975_1 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000007272 229.0
TLS3_k127_2393975_2 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000000000000000006636 226.0
TLS3_k127_2393975_3 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000008375 227.0
TLS3_k127_2393975_4 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000006773 187.0
TLS3_k127_2393975_5 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000001447 116.0
TLS3_k127_2393975_6 Alpha beta-Hydrolases superfamily protein - - - 0.00000000001013 74.0
TLS3_k127_2393975_7 Domain of unknown function (DUF4157) K02689,K02690 - - 0.00000001644 68.0
TLS3_k127_239445_0 PFAM oxidoreductase molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 447.0
TLS3_k127_239445_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441,K10562 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 432.0
TLS3_k127_239445_10 Histidine kinase - - - 0.0000000000000002606 86.0
TLS3_k127_239445_11 - - - - 0.000000000003674 70.0
TLS3_k127_239445_2 ABC-type sugar transport system periplasmic component K10439,K10543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 378.0
TLS3_k127_239445_3 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 318.0
TLS3_k127_239445_4 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001553 280.0
TLS3_k127_239445_5 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000005698 216.0
TLS3_k127_239445_6 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000001301 213.0
TLS3_k127_239445_7 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000003765 212.0
TLS3_k127_239445_8 Branched-chain amino acid transport system / permease component K02057,K10440,K17214 - - 0.000000000000000000000000000000000000000000000000000001427 213.0
TLS3_k127_239445_9 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000001295 170.0
TLS3_k127_2417605_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 345.0
TLS3_k127_2417605_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004267 280.0
TLS3_k127_2417605_2 Asp/Glu/Hydantoin racemase K01776,K02428 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000001183 238.0
TLS3_k127_2417605_3 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000105 237.0
TLS3_k127_2417605_4 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000006283 233.0
TLS3_k127_2417605_5 PFAM response regulator receiver K02282 - - 0.0000000000000000000000000000000000000000002197 173.0
TLS3_k127_2417605_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000001987 139.0
TLS3_k127_2418476_0 IMP dehydrogenase GMP reductase K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 399.0
TLS3_k127_2418476_1 ABC transporter K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 374.0
TLS3_k127_2418476_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 308.0
TLS3_k127_2418476_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000258 183.0
TLS3_k127_2418476_4 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000003679 78.0
TLS3_k127_2418476_5 Domain of unknown function (DUF4331) - - - 0.00000006275 57.0
TLS3_k127_2418536_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002155 283.0
TLS3_k127_2418536_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000004935 194.0
TLS3_k127_2418536_2 Aldo/keto reductase family - - - 0.0000000000000000000000000001203 128.0
TLS3_k127_2437743_0 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 491.0
TLS3_k127_2437743_1 - - - - 0.0000000000000000000000000000000000000000000002559 185.0
TLS3_k127_2437743_2 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 0.0000000000000000000000000000000000000000001179 165.0
TLS3_k127_2437743_3 PFAM DnaJ homologue, subfamily C, member 28 - - - 0.00000007795 61.0
TLS3_k127_2437743_4 F420H(2)-dependent quinone reductase - - - 0.000001002 59.0
TLS3_k127_2486260_0 Elongation factor G C-terminus K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 544.0
TLS3_k127_2486260_1 PFAM ABC transporter related K09972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 380.0
TLS3_k127_2486260_2 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 374.0
TLS3_k127_2486260_3 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 351.0
TLS3_k127_2486260_4 Binding-protein-dependent transport system inner membrane component K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 329.0
TLS3_k127_2486260_5 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000003556 249.0
TLS3_k127_2492158_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 316.0
TLS3_k127_2492158_1 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 291.0
TLS3_k127_2492158_2 transport, permease protein K01992 - - 0.000000000000000000000000000000000000009498 156.0
TLS3_k127_2492158_3 - - - - 0.0000000000000000000344 93.0
TLS3_k127_2492158_4 - - - - 0.0000001012 64.0
TLS3_k127_2515492_0 Dak1 domain K05878 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 503.0
TLS3_k127_2515492_1 ABC transporter K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000176 266.0
TLS3_k127_2515492_10 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000001382 179.0
TLS3_k127_2515492_11 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.0000000000000000000000000000003553 138.0
TLS3_k127_2515492_12 Putative single-stranded nucleic acids-binding domain K06346 - - 0.000000000000000000000000000077 120.0
TLS3_k127_2515492_13 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.000000000000000000000004284 115.0
TLS3_k127_2515492_14 Methicillin resistance protein - - - 0.0000000000000465 85.0
TLS3_k127_2515492_15 cellulose binding - - - 0.0000000004576 74.0
TLS3_k127_2515492_16 UTRA K03710 - - 0.0001792 48.0
TLS3_k127_2515492_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000002893 253.0
TLS3_k127_2515492_3 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000224 248.0
TLS3_k127_2515492_4 COG1070 Sugar (pentulose and hexulose) kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000001304 241.0
TLS3_k127_2515492_5 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000003932 206.0
TLS3_k127_2515492_6 Imidazole acetol-phosphate transaminase K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000006126 211.0
TLS3_k127_2515492_7 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000001475 202.0
TLS3_k127_2515492_8 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000206 212.0
TLS3_k127_2515492_9 Ribose 5-phosphate isomerase K01808 GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 5.3.1.6 0.0000000000000000000000000000000000000000000000004793 185.0
TLS3_k127_2516109_0 Belongs to the complex I 49 kDa subunit family K00333,K14090 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 466.0
TLS3_k127_2516109_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 329.0
TLS3_k127_2516109_2 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000001042 205.0
TLS3_k127_2516109_3 ABC-2 family transporter protein - - - 0.000000000000000000000000000002053 135.0
TLS3_k127_2516109_4 PFAM NADH ubiquinone oxidoreductase, 20 - - - 0.00000000000000000000001269 100.0
TLS3_k127_2516109_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K14091 - 1.6.5.3 0.000000000000000000004608 98.0
TLS3_k127_2516109_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K14089 - - 0.000000000000001513 85.0
TLS3_k127_2516109_7 4Fe-4S binding domain - - - 0.000000000000002719 80.0
TLS3_k127_2516109_8 LysM domain - - - 0.0000000003809 73.0
TLS3_k127_2531092_0 Aminotransferase class I and II K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 423.0
TLS3_k127_2531092_1 helicase superfamily c-terminal domain K03654 - 3.6.4.12 0.000002135 52.0
TLS3_k127_2539258_0 Isocitrate/isopropylmalate dehydrogenase K00030,K00031 - 1.1.1.41,1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 456.0
TLS3_k127_2539258_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 321.0
TLS3_k127_2539258_2 PFAM Inosine uridine-preferring nucleoside hydrolase K01239 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 323.0
TLS3_k127_2539258_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000005308 209.0
TLS3_k127_2539258_4 phosphorelay sensor kinase activity K16923,K18967 - 2.7.7.65 0.00000000000000001409 91.0
TLS3_k127_2544160_0 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 321.0
TLS3_k127_2544160_1 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000016 284.0
TLS3_k127_2544160_2 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000001261 187.0
TLS3_k127_2544160_3 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000001555 100.0
TLS3_k127_2544160_4 - - - - 0.0006373 44.0
TLS3_k127_2553607_0 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 603.0
TLS3_k127_2553607_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000008332 216.0
TLS3_k127_2553607_2 Kelch motif - - - 0.00000000000000000000000000000000000000000000000000000002108 214.0
TLS3_k127_2553607_3 - - - - 0.0000000000000000000000000000000000006373 142.0
TLS3_k127_2587801_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 337.0
TLS3_k127_2587801_1 cysteine-tRNA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 331.0
TLS3_k127_2587801_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 301.0
TLS3_k127_2587801_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002402 269.0
TLS3_k127_2587801_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000007676 232.0
TLS3_k127_2587801_5 AI-2E family transporter - - - 0.000000000000000000001115 111.0
TLS3_k127_2587801_6 AI-2E family transporter - - - 0.000000000000000000005918 109.0
TLS3_k127_261495_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 346.0
TLS3_k127_261495_1 Cell envelope-related transcriptional attenuator domain - - - 0.000000000000000000000000000006208 134.0
TLS3_k127_261495_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963,K03111,K15125 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001641 108.0
TLS3_k127_2623619_0 FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 7.295e-207 668.0
TLS3_k127_2623619_1 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 391.0
TLS3_k127_2623619_2 Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000002823 248.0
TLS3_k127_2623619_3 Binding-protein-dependent transport system inner membrane component K02026,K17236 - - 0.00000000000000000000000001149 112.0
TLS3_k127_2626569_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 2.988e-197 627.0
TLS3_k127_2626569_1 protein conserved in bacteria K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 597.0
TLS3_k127_2626569_2 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 304.0
TLS3_k127_2626569_3 carbohydrate transport K17234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001126 284.0
TLS3_k127_2626569_4 Arabinose transporter permease K17235 - - 0.00000000000000000000000000000000000000000000000003227 187.0
TLS3_k127_2626569_5 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000004931 141.0
TLS3_k127_2628039_0 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 396.0
TLS3_k127_2628039_1 Cellulose biosynthesis protein BcsQ K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000003776 256.0
TLS3_k127_2628039_2 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000001012 172.0
TLS3_k127_2628039_3 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000007011 166.0
TLS3_k127_2628039_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.0000000000001977 81.0
TLS3_k127_263033_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 384.0
TLS3_k127_263033_1 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 381.0
TLS3_k127_263033_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009661 259.0
TLS3_k127_263033_3 peptidase K05802,K06401,K20444,K22051 - - 0.000125 50.0
TLS3_k127_2647767_0 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.0 1049.0
TLS3_k127_2647767_1 Integrator complex subunit 3 K13140 - - 0.000004152 55.0
TLS3_k127_2663484_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000001936 187.0
TLS3_k127_2663484_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000001182 181.0
TLS3_k127_2663484_2 binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription in Mycobacterium bovis this protein has been shown to be active at high temperatures and during stationary phase K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000271 94.0
TLS3_k127_2663484_3 ATPase family associated with various cellular activities (AAA) K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000001493 78.0
TLS3_k127_2687932_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 375.0
TLS3_k127_2687932_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 346.0
TLS3_k127_2687932_2 binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 340.0
TLS3_k127_2687932_3 PFAM extracellular solute-binding protein family 1 K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 324.0
TLS3_k127_2687932_4 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 314.0
TLS3_k127_2687932_5 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000006917 220.0
TLS3_k127_2695480_0 Pterin binding enzyme K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002803 286.0
TLS3_k127_2695480_1 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001845 269.0
TLS3_k127_2695480_2 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000008858 174.0
TLS3_k127_2695480_3 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000004267 178.0
TLS3_k127_2695480_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000001135 94.0
TLS3_k127_2695480_5 Psort location Extracellular, score - - - 0.00000000882 68.0
TLS3_k127_2697711_0 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000266 210.0
TLS3_k127_2697711_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000008115 133.0
TLS3_k127_2716662_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 428.0
TLS3_k127_2716662_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 381.0
TLS3_k127_2716662_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000142 285.0
TLS3_k127_2716662_3 - - - - 0.0000000007299 72.0
TLS3_k127_2745565_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001701 246.0
TLS3_k127_2745565_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000004025 89.0
TLS3_k127_2752919_0 N-terminal Region. This family is found at the N-terminus of a number of subtilisins. It is cleaved prior to activation of the enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 543.0
TLS3_k127_2752919_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 445.0
TLS3_k127_2752919_2 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001543 234.0
TLS3_k127_2752919_3 Repeat of unknown function (DUF346) - - - 0.000000000000000000000000000000000000001768 152.0
TLS3_k127_2762243_0 Epoxide hydrolase N terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 618.0
TLS3_k127_2762243_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 414.0
TLS3_k127_2762243_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 308.0
TLS3_k127_2762243_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000003215 68.0
TLS3_k127_2766730_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 409.0
TLS3_k127_2766730_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000006833 158.0
TLS3_k127_2766730_2 cell redox homeostasis K02199 - - 0.000000000000000000000000000000000000003075 160.0
TLS3_k127_2766730_3 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000748 52.0
TLS3_k127_278572_0 Protein of unknown function (DUF3830) - - - 0.00000000000000000000000000000000000000000000000000000002269 201.0
TLS3_k127_278572_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000001096 200.0
TLS3_k127_278572_2 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000003113 83.0
TLS3_k127_278572_3 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.000000000001746 80.0
TLS3_k127_2786181_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 498.0
TLS3_k127_2786181_1 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 493.0
TLS3_k127_2786181_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 417.0
TLS3_k127_2787402_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000001958 259.0
TLS3_k127_2787402_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000002185 154.0
TLS3_k127_2787402_2 PFAM OsmC family protein K07397 - - 0.0000000000000000000009978 105.0
TLS3_k127_2787402_3 - - - - 0.00007202 54.0
TLS3_k127_2838906_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 409.0
TLS3_k127_2838906_1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002063 289.0
TLS3_k127_2838906_2 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000000000000000006117 215.0
TLS3_k127_2838906_3 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000002373 194.0
TLS3_k127_2838906_4 - - - - 0.000000000000000000000002659 112.0
TLS3_k127_2841571_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 414.0
TLS3_k127_2857277_0 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007966 285.0
TLS3_k127_2857277_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000005934 204.0
TLS3_k127_2857277_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000001263 157.0
TLS3_k127_2857277_3 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000002931 122.0
TLS3_k127_2857277_4 Protein of unknown function (DUF3224) - - - 0.00000000005806 73.0
TLS3_k127_2857277_5 Protein of unknown function (DUF1307) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000008875 59.0
TLS3_k127_2869412_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 1.373e-306 972.0
TLS3_k127_2873755_0 Trehalase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 615.0
TLS3_k127_2873755_1 Pyridoxal-phosphate dependent enzyme K01505,K05396 - 3.5.99.7,4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 540.0
TLS3_k127_2873755_2 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000002098 180.0
TLS3_k127_2882504_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.342e-220 703.0
TLS3_k127_2882504_1 - - - - 0.00000000000000000000001273 103.0
TLS3_k127_2882504_2 - - - - 0.0000000000000000000003504 106.0
TLS3_k127_2882504_3 - - - - 0.0000000000000000000004834 105.0
TLS3_k127_2882504_4 peptidase inhibitor activity - - - 0.0000000002793 72.0
TLS3_k127_2882504_5 cell adhesion involved in biofilm formation - - - 0.000004529 52.0
TLS3_k127_2882504_6 - - - - 0.0001731 53.0
TLS3_k127_2882504_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0005655 50.0
TLS3_k127_2893033_0 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 289.0
TLS3_k127_2893033_1 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000002526 198.0
TLS3_k127_2893033_2 Glycosyltransferase family 10 (fucosyltransferase) C-term - - - 0.000000000000000000000000000000000000000000001591 171.0
TLS3_k127_2893033_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000004766 76.0
TLS3_k127_2896443_0 Malate synthase K01638 - 2.3.3.9 2.147e-222 714.0
TLS3_k127_2896443_1 Bacterial extracellular solute-binding protein K02027,K10117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 520.0
TLS3_k127_2896443_2 Transcriptional regulator (LacI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 293.0
TLS3_k127_2896443_3 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000171 181.0
TLS3_k127_2896443_4 Catalyzes the dehydration of L-rhamnonate to 2-keto-3- deoxy-L-rhamnonate (KDR) - - - 0.000000000000000000000122 100.0
TLS3_k127_2896443_5 rhs-related protein - - - 0.00000000001655 77.0
TLS3_k127_2896443_6 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000005361 62.0
TLS3_k127_2896443_7 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000007923 59.0
TLS3_k127_2913947_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 547.0
TLS3_k127_2913947_1 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000006907 227.0
TLS3_k127_2913947_2 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000115 214.0
TLS3_k127_2913947_3 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000002701 191.0
TLS3_k127_2913947_4 Arylsulfatase a K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000008523 192.0
TLS3_k127_2922610_0 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 347.0
TLS3_k127_2922610_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000001387 89.0
TLS3_k127_2970629_0 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 320.0
TLS3_k127_2970629_1 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001771 267.0
TLS3_k127_2970629_2 SPTR C1WI92 Carbohydrate ABC transporter membrane protein 2, CUT1 family K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003852 277.0
TLS3_k127_2970629_3 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000009255 235.0
TLS3_k127_2970629_4 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000001089 160.0
TLS3_k127_297177_0 carboxylic acid catabolic process K18334 - 4.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 573.0
TLS3_k127_297177_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 353.0
TLS3_k127_297177_2 Belongs to the TPP enzyme family K04103 - 4.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004811 273.0
TLS3_k127_297177_3 Binding-protein-dependent transport system inner membrane component K10119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002842 254.0
TLS3_k127_297177_4 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000002701 171.0
TLS3_k127_2978723_0 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 302.0
TLS3_k127_2978723_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000003128 263.0
TLS3_k127_2978723_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000001019 137.0
TLS3_k127_2994868_0 PFAM metal-dependent phosphohydrolase, HD sub domain - GO:0003674,GO:0003824,GO:0004112,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009187,GO:0009214,GO:0009987,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000007893 185.0
TLS3_k127_2994868_1 D-aminopeptidase K16203 - - 0.0004308 46.0
TLS3_k127_3005420_0 FAD dependent oxidoreductase K00109 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 496.0
TLS3_k127_3005420_1 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000004882 254.0
TLS3_k127_3005420_2 asparagine synthase - - - 0.00000000000000000000000000000000000000000000000000000004066 216.0
TLS3_k127_3033582_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 416.0
TLS3_k127_3033582_1 RDD family - - - 0.00000009134 62.0
TLS3_k127_3103973_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 490.0
TLS3_k127_3103973_1 Ferritin-like domain K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000002668 243.0
TLS3_k127_3103973_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000001051 190.0
TLS3_k127_3103973_3 Sigma-70, region 4 K03088 - - 0.0000000000002477 78.0
TLS3_k127_3103973_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000001438 72.0
TLS3_k127_3103973_5 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00000001429 67.0
TLS3_k127_3113310_0 exo-alpha-(2->6)-sialidase activity - - - 4.175e-228 732.0
TLS3_k127_3113310_1 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 457.0
TLS3_k127_3113310_3 PDZ DHR GLGF domain protein - - - 0.000267 45.0
TLS3_k127_3116329_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 388.0
TLS3_k127_3116329_1 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002259 207.0
TLS3_k127_3148136_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 9.243e-216 682.0
TLS3_k127_3148136_1 L-lactate permease K03303 - - 8.598e-209 662.0
TLS3_k127_3148136_2 - - - - 0.00001614 53.0
TLS3_k127_3165369_0 Belongs to the SEDS family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002395 242.0
TLS3_k127_3165369_1 PFAM Forkhead-associated protein - - - 0.0000000000000006785 83.0
TLS3_k127_3165369_2 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.0000000002295 64.0
TLS3_k127_3169738_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 356.0
TLS3_k127_3169738_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000633 248.0
TLS3_k127_3169738_2 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000003624 195.0
TLS3_k127_3169738_3 DNA-binding transcription factor activity - - - 0.00000000000000000005902 100.0
TLS3_k127_3169738_4 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000007959 93.0
TLS3_k127_3169738_5 Dihydrodipicolinate synthetase family - - - 0.0000000001452 61.0
TLS3_k127_3169738_6 DNA-binding transcription factor activity - - - 0.000000217 62.0
TLS3_k127_3217065_0 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 2.314e-204 646.0
TLS3_k127_3217065_1 ATPases associated with a variety of cellular activities K02032 - - 0.00000000000000000000000000000000000000000000000000004055 194.0
TLS3_k127_3239714_0 PFAM peptidase M24 K01262,K01271,K01274 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000008594 141.0
TLS3_k127_3239714_1 Glyco_18 K01448,K07260,K20276 - 3.4.17.14,3.5.1.28 0.000000000000000000000003573 118.0
TLS3_k127_3239714_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000131 95.0
TLS3_k127_3245178_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K12953 - - 5.139e-307 967.0
TLS3_k127_3245178_1 Type III restriction enzyme res subunit - - - 6.004e-221 716.0
TLS3_k127_3245178_2 Belongs to the GbsR family - - - 0.00000000000121 78.0
TLS3_k127_3245178_3 Cell envelope-related transcriptional attenuator domain - - - 0.000000002008 71.0
TLS3_k127_3249382_0 cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 358.0
TLS3_k127_3249382_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000000000000000000000000000005346 130.0
TLS3_k127_329511_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 9e-323 1005.0
TLS3_k127_329511_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 390.0
TLS3_k127_329511_2 Large family of predicted nucleotide-binding domains - - - 0.000000001786 65.0
TLS3_k127_3332367_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 389.0
TLS3_k127_3332367_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K09699 - 2.3.1.12,2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 319.0
TLS3_k127_3332367_2 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.000000000000000000000000000000000000000000000000007092 183.0
TLS3_k127_3332367_3 malic protein domain protein K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000006572 169.0
TLS3_k127_3332754_0 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 503.0
TLS3_k127_3332754_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 392.0
TLS3_k127_3332754_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000252 287.0
TLS3_k127_3332754_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000001209 211.0
TLS3_k127_3332754_4 (ABC) transporter K01995 - - 0.000000000000001621 81.0
TLS3_k127_3368241_0 ATP dependent DNA ligase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 522.0
TLS3_k127_3368241_1 import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 478.0
TLS3_k127_3368241_10 Lytic transglycolase K03642 - - 0.00000000000000004722 93.0
TLS3_k127_3368241_11 PFAM regulatory protein, ArsR - - - 0.00000000000009066 75.0
TLS3_k127_3368241_12 PFAM heat shock protein DnaJ domain protein K05516 - - 0.000000003286 67.0
TLS3_k127_3368241_2 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 357.0
TLS3_k127_3368241_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 342.0
TLS3_k127_3368241_4 Branched-chain amino acid transport system / permease component K02057,K10440,K17209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 316.0
TLS3_k127_3368241_5 Periplasmic binding protein-like domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000002301 233.0
TLS3_k127_3368241_6 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000002917 191.0
TLS3_k127_3368241_7 PFAM periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000007134 190.0
TLS3_k127_3368241_8 belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000418 121.0
TLS3_k127_3368241_9 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000009825 119.0
TLS3_k127_3389957_0 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 322.0
TLS3_k127_3389957_1 zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000003115 199.0
TLS3_k127_3389957_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000004745 186.0
TLS3_k127_3389957_3 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.0000000000000000000372 100.0
TLS3_k127_3389957_4 Alpha beta hydrolase - - - 0.000000000000000002571 94.0
TLS3_k127_3427819_0 Highly conserved protein containing a thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 539.0
TLS3_k127_3427819_1 Belongs to the glycosyl hydrolase 31 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 411.0
TLS3_k127_3427819_2 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.000000000000000000000000000000000000000000000000000000000495 211.0
TLS3_k127_3462378_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 405.0
TLS3_k127_3462378_1 Phosphoglycerate mutase family K02226 GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000002897 228.0
TLS3_k127_3462378_2 cytochrome c biogenesis protein K06196 - - 0.0000000000000000000000000000000000000002283 163.0
TLS3_k127_3462378_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000053 118.0
TLS3_k127_3462378_4 Belongs to the FGGY kinase family K00880 - 2.7.1.53 0.00000000000000000000003144 102.0
TLS3_k127_3462378_5 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0006907 48.0
TLS3_k127_3466808_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 391.0
TLS3_k127_3466808_1 Fructose transport system kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003998 257.0
TLS3_k127_3466808_2 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002202 254.0
TLS3_k127_3466808_3 Acyl dehydratase K18290 - 4.2.1.56 0.0000000000000000000000000000000000000000000000000000002323 211.0
TLS3_k127_3466808_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000004755 98.0
TLS3_k127_3466808_5 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000002352 98.0
TLS3_k127_3468081_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 593.0
TLS3_k127_3468081_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 322.0
TLS3_k127_3468081_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000005139 102.0
TLS3_k127_3473502_0 Hemerythrin HHE cation binding domain K01534 - 3.6.3.3,3.6.3.5 2.558e-227 728.0
TLS3_k127_3473502_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003296 280.0
TLS3_k127_3473502_2 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003016 254.0
TLS3_k127_3473502_4 Nucleoside H+ symporter K05820 - - 0.0000000000000000001354 102.0
TLS3_k127_3474507_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 297.0
TLS3_k127_3474507_1 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.000000000000000000000000000000000000000000000002191 186.0
TLS3_k127_3477221_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 436.0
TLS3_k127_3477221_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 395.0
TLS3_k127_3477221_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000001503 206.0
TLS3_k127_3477221_3 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000007172 199.0
TLS3_k127_3477221_4 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000007383 179.0
TLS3_k127_3477221_5 AAA ATPase domain K01768 - 4.6.1.1 0.0002654 53.0
TLS3_k127_3519798_0 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 319.0
TLS3_k127_3519798_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004934 278.0
TLS3_k127_3519798_2 ABC 3 transport family K02075,K09816,K09819 - - 0.00000000000000000000000000000000000000003847 158.0
TLS3_k127_3519798_3 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000007804 139.0
TLS3_k127_3519798_4 CopC domain K14166 - - 0.0000000000000000000000000002299 133.0
TLS3_k127_3519798_5 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000221 105.0
TLS3_k127_3519798_6 Vitamin k epoxide reductase K00368 - 1.7.2.1 0.000000000003187 75.0
TLS3_k127_3530389_0 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000004586 256.0
TLS3_k127_3530389_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000331 182.0
TLS3_k127_3530389_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000006404 166.0
TLS3_k127_3530389_4 Uncharacterised protein family UPF0102 K07460 - - 0.000000001982 64.0
TLS3_k127_3551766_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 341.0
TLS3_k127_3551766_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000015 289.0
TLS3_k127_3551766_2 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000001274 259.0
TLS3_k127_3551766_3 Penicillin-binding protein, transpeptidase domain protein K03587,K08384 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000009999 254.0
TLS3_k127_3551766_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000001221 253.0
TLS3_k127_3551766_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000003755 222.0
TLS3_k127_3571037_0 ATPases associated with a variety of cellular activities K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 335.0
TLS3_k127_3571037_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 328.0
TLS3_k127_3571037_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000004327 179.0
TLS3_k127_3571037_3 FR47-like protein - - - 0.000000000004819 78.0
TLS3_k127_3578157_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.417e-194 632.0
TLS3_k127_3578157_1 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 456.0
TLS3_k127_3578157_10 phosphinothricin N-acetyltransferase activity K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000007136 174.0
TLS3_k127_3578157_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000008015 68.0
TLS3_k127_3578157_2 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 399.0
TLS3_k127_3578157_3 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 358.0
TLS3_k127_3578157_4 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 327.0
TLS3_k127_3578157_5 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007254 289.0
TLS3_k127_3578157_6 Participates in initiation and elongation during chromosome replication K02314,K02316,K17680 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000003536 247.0
TLS3_k127_3578157_7 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000001809 219.0
TLS3_k127_3578157_8 peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000001918 174.0
TLS3_k127_3578157_9 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000004002 184.0
TLS3_k127_3589814_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 370.0
TLS3_k127_3589814_1 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000579 290.0
TLS3_k127_3593089_0 phosphatase activity K07025,K20866 - 3.1.3.10 0.00000000000000000000000000000000003341 140.0
TLS3_k127_3593089_1 SMART Metal-dependent phosphohydrolase, HD region K07037 - - 0.00000000000000000000000000005827 119.0
TLS3_k127_3593089_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000001698 91.0
TLS3_k127_3593089_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520 - 1.16.1.1 0.00000000000000002816 86.0
TLS3_k127_3618674_0 regulatory protein, FmdB family - - - 0.00000001764 61.0
TLS3_k127_3618674_1 Virulence factor BrkB K07058 - - 0.000001733 59.0
TLS3_k127_3638478_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.451e-245 769.0
TLS3_k127_3638478_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 1.116e-211 663.0
TLS3_k127_3638478_10 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000001931 193.0
TLS3_k127_3638478_11 L-methionine salvage from methylthioadenosine K00058,K08966 - 1.1.1.399,1.1.1.95,3.1.3.87 0.000000000000000000000000000002873 131.0
TLS3_k127_3638478_12 Kelch motif - - - 0.000000000000000000000005636 117.0
TLS3_k127_3638478_13 RDD family - - - 0.00000000000000000001107 107.0
TLS3_k127_3638478_14 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000002959 84.0
TLS3_k127_3638478_15 Sigma-70 region 2 K03088 - - 0.000000000007675 77.0
TLS3_k127_3638478_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 598.0
TLS3_k127_3638478_3 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 439.0
TLS3_k127_3638478_4 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 332.0
TLS3_k127_3638478_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 326.0
TLS3_k127_3638478_6 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 319.0
TLS3_k127_3638478_7 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000675 278.0
TLS3_k127_3638478_8 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000003231 237.0
TLS3_k127_3638478_9 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000013 221.0
TLS3_k127_3647273_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 582.0
TLS3_k127_3647273_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000005179 189.0
TLS3_k127_3647273_11 Kdo2-lipid A biosynthetic process K02517,K22311 - 2.3.1.241,2.3.1.265 0.00004672 56.0
TLS3_k127_3647273_2 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000007699 182.0
TLS3_k127_3647273_3 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000003867 181.0
TLS3_k127_3647273_4 CDP-alcohol phosphatidyltransferase K00995,K00999 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 0.000000000000000000004178 105.0
TLS3_k127_3647273_5 Kdo2-lipid A biosynthetic process K02517,K22311 - 2.3.1.241,2.3.1.265 0.000000000000000006873 93.0
TLS3_k127_3647273_6 Sigma-70, region 4 K03088 - - 0.00000000000000005871 88.0
TLS3_k127_3647273_7 DNA-binding transcription factor activity K03892 - - 0.0000000000004161 74.0
TLS3_k127_3647273_8 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000123 78.0
TLS3_k127_3647273_9 Lipid A biosynthesis K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.00000000002346 76.0
TLS3_k127_3659214_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 627.0
TLS3_k127_3659214_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 494.0
TLS3_k127_3659214_2 PFAM SAICAR synthetase K01756,K01923 - 4.3.2.2,6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 456.0
TLS3_k127_3659214_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 319.0
TLS3_k127_3659214_4 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 314.0
TLS3_k127_3659214_5 AICARFT/IMPCHase bienzyme K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 314.0
TLS3_k127_3659214_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000275 268.0
TLS3_k127_3659214_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000001 74.0
TLS3_k127_3709976_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 608.0
TLS3_k127_3709976_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 558.0
TLS3_k127_3709976_10 CoA-binding protein K06929 - - 0.00000000000000000000000000004417 133.0
TLS3_k127_3709976_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000009112 98.0
TLS3_k127_3709976_12 PFAM membrane-flanked domain - - - 0.00000000001693 77.0
TLS3_k127_3709976_13 Helix-turn-helix domain K15773 - - 0.000149 53.0
TLS3_k127_3709976_2 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 525.0
TLS3_k127_3709976_3 aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 487.0
TLS3_k127_3709976_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 456.0
TLS3_k127_3709976_5 Acetyltransferase (GNAT) domain K00663,K03790 - 2.3.1.128,2.3.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 331.0
TLS3_k127_3709976_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002519 275.0
TLS3_k127_3709976_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005974 274.0
TLS3_k127_3709976_8 PFAM ABC transporter related K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001763 253.0
TLS3_k127_3709976_9 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000003516 194.0
TLS3_k127_3720858_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 323.0
TLS3_k127_3727514_0 E1-E2 ATPase K01533 - 3.6.3.4 7.697e-243 790.0
TLS3_k127_3727514_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 584.0
TLS3_k127_3727514_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 351.0
TLS3_k127_3727514_3 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000185 267.0
TLS3_k127_3727514_4 membrane protein of uknown function UCP014873 - - - 0.000000000000000000000000000000000000000000000000000001082 202.0
TLS3_k127_3727514_5 Isochorismatase family - - - 0.00000000000000000000000004887 116.0
TLS3_k127_3727514_6 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000000004925 102.0
TLS3_k127_3758189_0 PFAM Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 608.0
TLS3_k127_3758189_1 AAA domain - - - 0.000000000000000000000000000000000000000000178 163.0
TLS3_k127_3758189_2 Reverse transcriptase-like K03469,K22316 - 3.1.26.4,3.1.3.73 0.00000000000000000000000004109 112.0
TLS3_k127_3760737_0 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 364.0
TLS3_k127_3760737_1 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
TLS3_k127_3760737_2 - - - - 0.0000000000000000000000000000000000000000000000000005474 196.0
TLS3_k127_3760737_3 Domain of unknown function (DU1801) - - - 0.00000000000000000000003584 104.0
TLS3_k127_3760737_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000003134 105.0
TLS3_k127_3771302_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003445 285.0
TLS3_k127_3771302_1 Sulfotransferase family - - - 0.000000000000000000000000004526 125.0
TLS3_k127_3789481_0 Acetyl xylan esterase (AXE1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 494.0
TLS3_k127_3789481_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 325.0
TLS3_k127_3789481_2 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000001145 163.0
TLS3_k127_3789481_3 - - - - 0.00000001674 63.0
TLS3_k127_3796836_0 Aldolase K01624,K08302 - 4.1.2.13,4.1.2.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 342.0
TLS3_k127_3796836_1 pfkB family carbohydrate kinase K00882,K00917 - 2.7.1.144,2.7.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002186 288.0
TLS3_k127_3796836_2 sugar isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001054 255.0
TLS3_k127_3796836_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000002096 248.0
TLS3_k127_3796836_4 SpoU rRNA Methylase family K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000001181 239.0
TLS3_k127_3802131_0 Protein of unknown function (DUF4012) - - - 0.00000000000000000000000000000000000002179 166.0
TLS3_k127_3802131_1 peptidase C60 sortase A and B - - - 0.0000000000000497 83.0
TLS3_k127_3831750_0 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 453.0
TLS3_k127_3831750_1 Xylose isomerase-like TIM barrel K06605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 432.0
TLS3_k127_3831750_2 COG1129 ABC-type sugar transport system, ATPase component K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 358.0
TLS3_k127_3831750_3 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 328.0
TLS3_k127_3831750_4 Periplasmic binding protein domain K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 301.0
TLS3_k127_3831750_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 309.0
TLS3_k127_3831750_6 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000497 200.0
TLS3_k127_3831750_7 PFAM PfkB domain protein - - - 0.0000000000002468 82.0
TLS3_k127_3868022_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 394.0
TLS3_k127_3868022_1 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000169 162.0
TLS3_k127_3878017_0 Peptidoglycan-binding domain 1 protein - - - 2.638e-271 865.0
TLS3_k127_3878017_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 429.0
TLS3_k127_3878017_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000005693 228.0
TLS3_k127_3878017_3 - - - - 0.0000004591 56.0
TLS3_k127_3879404_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 334.0
TLS3_k127_3879404_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000001031 145.0
TLS3_k127_3880965_0 Required for the activity of the bacterial periplasmic transport system of putrescine K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 534.0
TLS3_k127_3880965_1 Belongs to the ABC transporter superfamily K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 445.0
TLS3_k127_3880965_2 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006414 252.0
TLS3_k127_3880965_3 4Fe-4S binding domain K05524 - - 0.000000000000000000000000000005805 122.0
TLS3_k127_3880965_4 - - - - 0.0000008463 58.0
TLS3_k127_3880965_5 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000511 51.0
TLS3_k127_3919284_0 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 342.0
TLS3_k127_3919284_1 PFAM ABC transporter K09820,K11603 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001846 264.0
TLS3_k127_3919284_2 ABC-3 protein K09816,K09819 - - 0.000000000000000000000000000000000000000000002391 167.0
TLS3_k127_3920427_0 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 342.0
TLS3_k127_3920427_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 338.0
TLS3_k127_3920427_2 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 291.0
TLS3_k127_3920427_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001484 262.0
TLS3_k127_3920427_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000003201 136.0
TLS3_k127_3935978_0 UDP-galactopyranose mutase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 516.0
TLS3_k127_3935978_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 395.0
TLS3_k127_3935978_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 370.0
TLS3_k127_3935978_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 326.0
TLS3_k127_3935978_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000001036 184.0
TLS3_k127_3935978_5 Predicted membrane protein (DUF2243) - - - 0.000000000000000000000000000000000000000000000002802 183.0
TLS3_k127_3935978_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000986 91.0
TLS3_k127_3935978_7 ketosteroid isomerase - - - 0.00006766 51.0
TLS3_k127_3963762_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 4.994e-196 649.0
TLS3_k127_3963762_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 359.0
TLS3_k127_3963762_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000004765 235.0
TLS3_k127_3963762_3 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002148 234.0
TLS3_k127_3963762_4 Putative sugar-binding domain - - - 0.00000000000000000000000003526 113.0
TLS3_k127_3964694_0 Beta-mannosidase K01192 - 3.2.1.25 9.487e-233 750.0
TLS3_k127_3964694_1 polygalacturonase activity - - - 0.00000006915 64.0
TLS3_k127_3972597_0 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 455.0
TLS3_k127_3972597_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 448.0
TLS3_k127_3972597_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
TLS3_k127_3972597_3 water channel activity K09884 - - 0.000000000000000000000000000001145 131.0
TLS3_k127_3972597_4 - - - - 0.000000001147 71.0
TLS3_k127_3976301_1 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity K13669 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00006907 54.0
TLS3_k127_4005959_0 Cellobiose phosphorylase K00702,K13688,K18675 - 2.4.1.20,2.4.1.280 0.0 1448.0
TLS3_k127_4005959_1 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1119.0
TLS3_k127_4008137_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 2.296e-201 659.0
TLS3_k127_4008137_1 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000004767 79.0
TLS3_k127_4009832_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008473 280.0
TLS3_k127_4009832_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000008518 162.0
TLS3_k127_4009832_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000001832 145.0
TLS3_k127_4009832_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000005382 124.0
TLS3_k127_4009832_4 ComEA protein K02237 - - 0.0000000000000000000000005746 110.0
TLS3_k127_4009832_5 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000003347 82.0
TLS3_k127_4009832_6 SMART Metal-dependent phosphohydrolase, HD region K07141 - 2.7.7.76 0.00000004912 64.0
TLS3_k127_4011363_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 567.0
TLS3_k127_4011363_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 324.0
TLS3_k127_4011363_2 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000003287 226.0
TLS3_k127_4011363_3 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000003349 163.0
TLS3_k127_4020748_0 Cell division protein FtsA K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 456.0
TLS3_k127_4020748_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 349.0
TLS3_k127_4020748_10 PFAM CAAX amino terminal protease family K07052 - - 0.00000003576 65.0
TLS3_k127_4020748_11 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000002727 60.0
TLS3_k127_4020748_12 Glycosyl transferases group 1 - - - 0.000003423 59.0
TLS3_k127_4020748_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 314.0
TLS3_k127_4020748_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000003559 269.0
TLS3_k127_4020748_4 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000002918 218.0
TLS3_k127_4020748_5 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000001456 181.0
TLS3_k127_4020748_6 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000338 138.0
TLS3_k127_4020748_7 exodeoxyribonuclease I activity - - - 0.000000000000000000000005743 110.0
TLS3_k127_4020748_8 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000003299 107.0
TLS3_k127_4020748_9 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000005452 106.0
TLS3_k127_4048852_0 malic protein domain protein K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 365.0
TLS3_k127_4048852_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000003568 246.0
TLS3_k127_4091553_0 Glycosyl transferase family 2 K11936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 495.0
TLS3_k127_4091553_1 amine oxidase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 350.0
TLS3_k127_4091553_11 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000008848 59.0
TLS3_k127_4091553_2 Monooxygenase fad-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 335.0
TLS3_k127_4091553_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001938 256.0
TLS3_k127_4091553_4 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000006255 238.0
TLS3_k127_4091553_5 DNA polymerase alpha chain like domain K04477 - - 0.0000000000000000000000000000000000000000000000000000001348 203.0
TLS3_k127_4091553_6 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000007405 189.0
TLS3_k127_4091553_7 - - - - 0.0000000000000000000000000000000000000219 155.0
TLS3_k127_4091553_8 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000001131 153.0
TLS3_k127_4091553_9 Polyketide cyclase - - - 0.000000000000000003824 91.0
TLS3_k127_4115950_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 430.0
TLS3_k127_4115950_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 372.0
TLS3_k127_4115950_10 phosphate binding protein K02040 - - 0.0000000000000000000000000137 112.0
TLS3_k127_4115950_11 Phosphoglycerate mutase family - - - 0.0000000000009229 76.0
TLS3_k127_4115950_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 330.0
TLS3_k127_4115950_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001319 288.0
TLS3_k127_4115950_4 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001181 275.0
TLS3_k127_4115950_5 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001446 263.0
TLS3_k127_4115950_6 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003964 257.0
TLS3_k127_4115950_7 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000004096 221.0
TLS3_k127_4115950_8 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000005592 156.0
TLS3_k127_4128626_0 Phage tail sheath C-terminal domain K06907 - - 1.189e-221 702.0
TLS3_k127_4128626_1 - - - - 0.00000000000000000000000000000000000000000000000001296 191.0
TLS3_k127_4128626_2 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000003724 162.0
TLS3_k127_4128626_3 Kelch motif - - - 0.000000000000000000004018 106.0
TLS3_k127_4139473_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 4.188e-210 681.0
TLS3_k127_4139473_1 PFAM isochorismatase hydrolase K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000007782 227.0
TLS3_k127_4139473_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000117 241.0
TLS3_k127_4139473_3 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000009081 162.0
TLS3_k127_4139473_4 Ferric uptake regulator family K03711 - - 0.000000000000000000000001716 110.0
TLS3_k127_4139473_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000002182 65.0
TLS3_k127_4140668_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 3.917e-291 899.0
TLS3_k127_4140668_1 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 513.0
TLS3_k127_4140668_2 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 297.0
TLS3_k127_4140668_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000307 210.0
TLS3_k127_4140668_4 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000002011 196.0
TLS3_k127_4140668_5 Sap, sulfolipid-1-addressing protein - - - 0.0000000000000000000000000000000000000000000000000003872 192.0
TLS3_k127_4140668_6 InterPro IPR014922 - - - 0.000000000000000000000000000000000000000000000007283 179.0
TLS3_k127_4140668_7 - - - - 0.000000000000000000000000000000000001808 143.0
TLS3_k127_4140668_8 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000005971 131.0
TLS3_k127_4140668_9 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000002498 120.0
TLS3_k127_4143773_0 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000349 275.0
TLS3_k127_4143773_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000006325 205.0
TLS3_k127_4145558_0 PFAM alanine racemase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001428 280.0
TLS3_k127_4145558_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002399 262.0
TLS3_k127_4145558_2 succinyl-diaminopimelate desuccinylase activity - - - 0.0000000000000007524 83.0
TLS3_k127_4149220_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1772.0
TLS3_k127_4149220_1 peptidase K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 336.0
TLS3_k127_4149220_2 Mur ligase middle domain K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 334.0
TLS3_k127_4173416_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 374.0
TLS3_k127_4173416_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 326.0
TLS3_k127_4173416_2 Glyco_18 - - - 0.00000000000001571 87.0
TLS3_k127_4173416_3 - - - - 0.0003048 51.0
TLS3_k127_4173690_0 TIGRFAM amino acid adenylation domain - - - 7.606e-196 628.0
TLS3_k127_4173690_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 561.0
TLS3_k127_4173690_2 TPM domain K06872 - - 0.00001702 57.0
TLS3_k127_4189380_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000179 134.0
TLS3_k127_4189380_1 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000001517 85.0
TLS3_k127_4189380_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000004818 70.0
TLS3_k127_4197281_0 ABC 3 transport family K09816,K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 315.0
TLS3_k127_4197281_1 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005735 268.0
TLS3_k127_4197281_2 Zinc-uptake complex component A periplasmic K02077,K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000382 256.0
TLS3_k127_4197281_3 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000006203 113.0
TLS3_k127_4197281_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000005328 106.0
TLS3_k127_4197281_5 - - - - 0.00000000000000000000007208 107.0
TLS3_k127_4211015_0 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 415.0
TLS3_k127_4211015_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000327 158.0
TLS3_k127_4211015_2 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.00000000000002245 80.0
TLS3_k127_4211015_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000001229 52.0
TLS3_k127_4228747_0 helix_turn_helix, Lux Regulon K02479 - - 0.0000000000000000000000000000000000000000000000000000000000007975 220.0
TLS3_k127_4228747_1 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000000000000000000005159 205.0
TLS3_k127_4228747_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000965 180.0
TLS3_k127_4228747_3 PFAM ROK family protein - - - 0.000000000000000000000000000005216 132.0
TLS3_k127_4228747_4 Methyltransferase domain K07003 - - 0.0000000000000000006999 98.0
TLS3_k127_4228747_5 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000004625 57.0
TLS3_k127_4236125_0 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 428.0
TLS3_k127_4236125_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000026 118.0
TLS3_k127_4236125_2 - - - - 0.00000000000000006554 87.0
TLS3_k127_4236125_3 Parallel beta-helix repeats - - - 0.00001091 59.0
TLS3_k127_4236125_4 protein conserved in bacteria - - - 0.00007893 54.0
TLS3_k127_4237184_0 ABC transporter - - - 1.677e-271 849.0
TLS3_k127_4237184_1 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 293.0
TLS3_k127_4237184_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000002447 265.0
TLS3_k127_4237184_3 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004677 240.0
TLS3_k127_4237184_4 Putative esterase K07017 - - 0.0000000000000000000000000000000000000000000000000000000001069 228.0
TLS3_k127_4237184_5 Pfam:DUF2029 - - - 0.00000000000000000000000000000000000000000001173 174.0
TLS3_k127_4237184_6 transmembrane transport K02025,K15771 - - 0.000000000000000000000000000000003708 131.0
TLS3_k127_42580_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1284.0
TLS3_k127_42580_1 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000002045 217.0
TLS3_k127_42580_2 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000004549 213.0
TLS3_k127_42580_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000007328 61.0
TLS3_k127_42580_4 Helicase K03658 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1902494 3.6.4.12 0.00008235 46.0
TLS3_k127_4268370_0 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 440.0
TLS3_k127_4268370_1 ATP:ADP antiporter activity K15762 - - 0.0000000008175 72.0
TLS3_k127_4268370_2 HEAT repeats K00239 - 1.3.5.1,1.3.5.4 0.0001219 55.0
TLS3_k127_427497_0 HhH-GPD superfamily base excision DNA repair protein - - - 0.0000000000000000000000000000003762 136.0
TLS3_k127_427497_1 Autoinducer binding domain - - - 0.000007279 57.0
TLS3_k127_4279006_0 Acetyl xylan esterase (AXE1) - - - 1.79e-203 642.0
TLS3_k127_4279006_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 496.0
TLS3_k127_4279006_10 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.00000000000000000000000004968 114.0
TLS3_k127_4279006_11 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000007459 69.0
TLS3_k127_4279006_2 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 470.0
TLS3_k127_4279006_3 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 395.0
TLS3_k127_4279006_4 PFAM ABC transporter related K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 335.0
TLS3_k127_4279006_5 cytosine deaminase K01485 GO:0003674,GO:0003824,GO:0004131,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006206,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009451,GO:0009987,GO:0016070,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019858,GO:0034641,GO:0034654,GO:0043094,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046087,GO:0046131,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000001898 215.0
TLS3_k127_4279006_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000005665 199.0
TLS3_k127_4279006_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000002365 156.0
TLS3_k127_4279006_8 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000005109 149.0
TLS3_k127_4279006_9 ThiS family K03636 - - 0.000000000000000000000000003896 113.0
TLS3_k127_4288736_0 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 424.0
TLS3_k127_4288736_1 Aminotransferase class-V K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 352.0
TLS3_k127_4288736_2 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000147 221.0
TLS3_k127_4288736_3 Protein of unknown function (DUF4446) - - - 0.0000000000000005769 87.0
TLS3_k127_4288736_4 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000002008 64.0
TLS3_k127_4320046_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 312.0
TLS3_k127_4320046_1 Aldolase K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 311.0
TLS3_k127_4320046_2 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 300.0
TLS3_k127_4320046_3 YceI-like domain - - - 0.000000000000003405 88.0
TLS3_k127_4320046_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000451 67.0
TLS3_k127_4320046_5 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000005786 59.0
TLS3_k127_4337861_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 389.0
TLS3_k127_4337861_1 ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004004 244.0
TLS3_k127_4337861_2 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000002098 146.0
TLS3_k127_4337861_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000003436 134.0
TLS3_k127_4337861_4 Universal stress protein family - - - 0.0000000000000417 81.0
TLS3_k127_4338805_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.628e-272 863.0
TLS3_k127_4338805_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 410.0
TLS3_k127_4338805_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 396.0
TLS3_k127_4338805_3 DNA alkylation repair - - - 0.0000001288 63.0
TLS3_k127_4338805_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000003145 58.0
TLS3_k127_4368031_0 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 399.0
TLS3_k127_4368031_1 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000001038 190.0
TLS3_k127_4368031_2 N-terminal domain of toast_rack, DUF2154 - - - 0.0000009124 61.0
TLS3_k127_4368031_3 - - - - 0.0005948 42.0
TLS3_k127_4370487_0 PFAM CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 509.0
TLS3_k127_4370487_1 Dehydrogenase K00059,K20900 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0030246,GO:0042221,GO:0044238,GO:0047880,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 1.1.1.100,1.1.1.403 0.0000000000000000000000000000000000000000000000000008993 199.0
TLS3_k127_4370487_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000001344 150.0
TLS3_k127_4370487_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.00000000000000000000000003948 126.0
TLS3_k127_4370487_4 muconolactone delta-isomerase K03464 - 5.3.3.4 0.0000000000000000000000002057 112.0
TLS3_k127_4370513_0 E3 component of the branched-chain alpha-keto acid dehydrogenase complex K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 329.0
TLS3_k127_4370513_1 A G-specific adenine glycosylase K03575 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000001846 206.0
TLS3_k127_4370513_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000002757 136.0
TLS3_k127_4370513_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000005795 140.0
TLS3_k127_4377592_0 Neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000000000000006464 230.0
TLS3_k127_4377592_1 ATPases associated with a variety of cellular activities K15555 - - 0.0000000000000000000000000008982 116.0
TLS3_k127_4377592_2 glyoxalase III activity - - - 0.000000000000000000000000005028 121.0
TLS3_k127_4385768_0 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 404.0
TLS3_k127_4385768_1 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 357.0
TLS3_k127_4385768_10 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000002005 59.0
TLS3_k127_4385768_2 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 307.0
TLS3_k127_4385768_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007537 271.0
TLS3_k127_4385768_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000002051 238.0
TLS3_k127_4385768_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000001387 218.0
TLS3_k127_4385768_6 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000009083 213.0
TLS3_k127_4385768_7 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.0000000000000000000000000000004257 132.0
TLS3_k127_4385768_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000001717 137.0
TLS3_k127_4385768_9 XdhC Rossmann domain K07402 - - 0.000000000000000003949 85.0
TLS3_k127_4394479_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000009234 140.0
TLS3_k127_4394479_2 Lysin motif - - - 0.00007371 54.0
TLS3_k127_4398985_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 595.0
TLS3_k127_4398985_1 ABC-type Fe3 transport system permease component K02011,K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008813 460.0
TLS3_k127_4398985_2 Bacterial extracellular solute-binding protein K02064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 359.0
TLS3_k127_4398985_3 Belongs to the ABC transporter superfamily K02052,K02062 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 362.0
TLS3_k127_4398985_4 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001874 248.0
TLS3_k127_4398985_5 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.0000000000000000000000000000000000000001582 166.0
TLS3_k127_4398985_6 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000002652 89.0
TLS3_k127_4408498_0 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 589.0
TLS3_k127_4408498_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 493.0
TLS3_k127_4408498_10 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000008713 85.0
TLS3_k127_4408498_11 - - - - 0.00000001149 68.0
TLS3_k127_4408498_2 PFAM Acetyl xylan esterase K01060 - 3.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 410.0
TLS3_k127_4408498_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 401.0
TLS3_k127_4408498_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000002757 232.0
TLS3_k127_4408498_5 transcriptional regulator K22491 - - 0.0000000000000000000000000000000000000000000000000000000000005334 222.0
TLS3_k127_4408498_6 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000008654 154.0
TLS3_k127_4408498_7 Glycosyl hydrolase family 26 - - - 0.000000000000000000000000000000000004468 151.0
TLS3_k127_4408498_8 transcriptional regulator - - - 0.0000000000000000000000000000007599 128.0
TLS3_k127_4408498_9 YCII-related domain - - - 0.00000000000000000000000000218 115.0
TLS3_k127_44085_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 338.0
TLS3_k127_44085_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 334.0
TLS3_k127_44085_2 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003532 258.0
TLS3_k127_44085_3 DRTGG domain K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002595 254.0
TLS3_k127_44085_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000002325 205.0
TLS3_k127_44085_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000001106 76.0
TLS3_k127_4414297_0 B12 binding domain K00548 - 2.1.1.13 1.019e-194 616.0
TLS3_k127_4414297_1 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000004776 130.0
TLS3_k127_4424379_0 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 358.0
TLS3_k127_4424379_1 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000001046 120.0
TLS3_k127_4444268_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 574.0
TLS3_k127_4444268_1 DegT/DnrJ/EryC1/StrS aminotransferase family K02805 - 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 377.0
TLS3_k127_4444268_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001397 176.0
TLS3_k127_4444268_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000001862 116.0
TLS3_k127_4444268_4 Acyltransferase family - - - 0.000000000000000000002225 108.0
TLS3_k127_4463206_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 615.0
TLS3_k127_4463206_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 543.0
TLS3_k127_4463206_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 325.0
TLS3_k127_4463206_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 312.0
TLS3_k127_4463206_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000005443 254.0
TLS3_k127_4463206_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000005745 231.0
TLS3_k127_4463206_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000007679 205.0
TLS3_k127_4463206_7 zinc metalloprotease K04771,K11749,K16922 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 0.0000000000000000000000000000000000000000000000006767 190.0
TLS3_k127_4463206_8 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000126 128.0
TLS3_k127_4471083_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 393.0
TLS3_k127_4471083_1 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001338 256.0
TLS3_k127_4471083_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000001013 248.0
TLS3_k127_4496173_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 6.856e-235 754.0
TLS3_k127_4496173_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 608.0
TLS3_k127_4496173_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 287.0
TLS3_k127_4496173_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000002029 220.0
TLS3_k127_4496173_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000004253 223.0
TLS3_k127_4496173_5 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000203 198.0
TLS3_k127_4496173_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000004443 131.0
TLS3_k127_4496173_7 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000002289 137.0
TLS3_k127_4496173_8 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.00000000000000000000000001808 115.0
TLS3_k127_4538805_0 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 439.0
TLS3_k127_4538805_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001368 266.0
TLS3_k127_4538805_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000001214 200.0
TLS3_k127_4538805_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000001963 159.0
TLS3_k127_4538805_4 BioY protein K03523 - - 0.00000000000000000000000000000000001279 146.0
TLS3_k127_4538805_5 ABC-2 family transporter protein K01992 - - 0.00000000002712 74.0
TLS3_k127_4538805_6 hydroxymethylglutaryl-CoA reductase K00021 - 1.1.1.34 0.00000000003036 74.0
TLS3_k127_4554699_0 Baseplate J-like protein - - - 6.313e-246 776.0
TLS3_k127_4554699_1 Phage baseplate assembly protein W K06903 - - 0.00000000000000000000000000000000000000000000000000000005749 198.0
TLS3_k127_4554699_2 Phage tail protein (Tail_P2_I) - - - 0.000000000000000000000000000000000000000000000000000003234 198.0
TLS3_k127_4554699_3 PAAR motif - - - 0.000000000000000000000000000000000000002323 152.0
TLS3_k127_4592255_0 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005823 287.0
TLS3_k127_4592255_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000003005 220.0
TLS3_k127_4638037_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000002487 162.0
TLS3_k127_4638037_1 DNA-binding transcription factor activity - - - 0.00000000000000000000001092 111.0
TLS3_k127_4638037_2 Family 5 K02035,K15580 - - 0.000000000000000000000337 105.0
TLS3_k127_4638037_3 aminopeptidase N - - - 0.0000000001515 74.0
TLS3_k127_4642948_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 412.0
TLS3_k127_4642948_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 378.0
TLS3_k127_4642948_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000503 210.0
TLS3_k127_4642948_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000004959 128.0
TLS3_k127_4643077_0 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009391 263.0
TLS3_k127_4643077_1 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000002866 224.0
TLS3_k127_4643077_2 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000003469 206.0
TLS3_k127_4643077_3 Acetyltransferase (GNAT) domain K00657,K00663 - 2.3.1.57,2.3.1.82 0.0000000000000000000000000000000000000000000000000001061 194.0
TLS3_k127_4643077_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000003309 141.0
TLS3_k127_4643077_5 Putative restriction endonuclease - - - 0.0000000000000003054 84.0
TLS3_k127_4643077_6 - - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000009818 83.0
TLS3_k127_47191_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 413.0
TLS3_k127_47191_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 376.0
TLS3_k127_47191_2 PFAM ABC transporter related K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 319.0
TLS3_k127_47191_3 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 308.0
TLS3_k127_47191_4 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
TLS3_k127_47191_5 ABC transporter, permease protein K02029,K02030,K09971,K17062 - - 0.000000000000000000000000000000000000000000000000000001229 202.0
TLS3_k127_47191_6 Belongs to the bacterial solute-binding protein 3 family - - - 0.00000000000000000000000000000000000000007051 158.0
TLS3_k127_474099_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 391.0
TLS3_k127_474099_1 4-phosphoerythronate dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 363.0
TLS3_k127_474099_10 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000000000000000005561 137.0
TLS3_k127_474099_11 Xylose isomerase-like TIM barrel - - - 0.000000001708 69.0
TLS3_k127_474099_12 transcriptional regulator, SARP family - - - 0.00000068 62.0
TLS3_k127_474099_2 carbohydrate transport K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 313.0
TLS3_k127_474099_3 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 301.0
TLS3_k127_474099_4 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 293.0
TLS3_k127_474099_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009216 267.0
TLS3_k127_474099_6 Epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000006766 235.0
TLS3_k127_474099_7 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000002819 227.0
TLS3_k127_474099_8 Bacterial extracellular solute-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000384 181.0
TLS3_k127_474099_9 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000009465 185.0
TLS3_k127_4744810_0 Na+/H+ antiporter 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 579.0
TLS3_k127_4744810_1 FAD linked oxidase domain protein K00594 - 1.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 381.0
TLS3_k127_4744810_2 pyridoxamine 5-phosphate K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000003422 232.0
TLS3_k127_4744810_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000002397 222.0
TLS3_k127_4744810_4 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000005306 167.0
TLS3_k127_4744810_5 Dodecin - - - 0.000000000000000000006529 95.0
TLS3_k127_4744810_6 DNA-templated transcription, initiation - - - 0.0000000000001207 83.0
TLS3_k127_474814_0 thiamine pyrophosphate protein TPP binding domain protein K03336 - 3.7.1.22 1.484e-197 637.0
TLS3_k127_474814_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 347.0
TLS3_k127_474814_2 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.00000000000000000000000000000000000000000000000000001145 200.0
TLS3_k127_474814_3 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.000000000000000000000000000000000000000000000004833 184.0
TLS3_k127_474814_4 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000001495 180.0
TLS3_k127_474814_5 transcriptional regulator - - - 0.0000000000000000000000000000000000000002746 164.0
TLS3_k127_474814_6 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000004328 102.0
TLS3_k127_4759291_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 387.0
TLS3_k127_4759291_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001781 191.0
TLS3_k127_4760390_0 Glycosyl transferases group 1 K00696,K13058 - 2.4.1.14,2.4.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 524.0
TLS3_k127_4760390_1 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 411.0
TLS3_k127_4760390_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 358.0
TLS3_k127_4760390_3 HAD-superfamily hydrolase, subfamily IIB K00696 - 2.4.1.14 0.000000000000000000000000000000000000000162 166.0
TLS3_k127_4760390_4 Transcriptional regulatory protein, C terminal K02483,K07667 - - 0.00000000000000000000000000000000000023 150.0
TLS3_k127_4760390_5 Histidine kinase K07646 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000002284 126.0
TLS3_k127_4760390_6 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000003495 94.0
TLS3_k127_4760390_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00001613 53.0
TLS3_k127_4768308_0 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 373.0
TLS3_k127_4768308_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000879 234.0
TLS3_k127_4768308_2 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000001279 185.0
TLS3_k127_4768308_3 FemAB family K05363,K11693 - 2.3.2.10,2.3.2.16 0.000000000000000000000000000002097 135.0
TLS3_k127_4812029_0 R3H domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 552.0
TLS3_k127_4812029_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 327.0
TLS3_k127_4812029_2 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 307.0
TLS3_k127_4812029_3 Domain of unknown function (DUF4331) - - - 0.000000000000000000000000000000000000000000000000000000000001272 224.0
TLS3_k127_4812029_4 SMART HNH nuclease - - - 0.000000000000000000000000000000000000000000000000000001367 200.0
TLS3_k127_4812029_5 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000007649 190.0
TLS3_k127_4812029_6 - - - - 0.0000007521 61.0
TLS3_k127_4812029_7 domain protein - - - 0.00001732 52.0
TLS3_k127_4814137_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K00058,K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 451.0
TLS3_k127_4814137_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000003408 213.0
TLS3_k127_4814137_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000001717 193.0
TLS3_k127_4814137_3 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000001358 186.0
TLS3_k127_4814137_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000006365 156.0
TLS3_k127_4814137_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000002056 122.0
TLS3_k127_4814137_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000002744 102.0
TLS3_k127_482006_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.917e-259 830.0
TLS3_k127_482006_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002 268.0
TLS3_k127_482006_2 - - - - 0.000000000000000000000000000000000000000000009331 163.0
TLS3_k127_482006_3 Ion channel K10716 - - 0.000000000000000000000000000000000000127 153.0
TLS3_k127_482006_4 Transcriptional regulator - - - 0.00000000000000000000000000000848 129.0
TLS3_k127_482006_5 membrane protein of uknown function UCP014873 - - - 0.000000000000000000000002501 102.0
TLS3_k127_4833677_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000002795 134.0
TLS3_k127_4833677_1 AraC-like ligand binding domain - - - 0.00000000000000000000003683 103.0
TLS3_k127_4833677_2 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000009754 89.0
TLS3_k127_4852828_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 430.0
TLS3_k127_4852828_1 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 320.0
TLS3_k127_4852828_2 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000697 275.0
TLS3_k127_4852828_3 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003882 277.0
TLS3_k127_4855915_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 315.0
TLS3_k127_4855915_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000348 236.0
TLS3_k127_4855915_10 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000001554 75.0
TLS3_k127_4855915_2 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000003727 203.0
TLS3_k127_4855915_3 binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000023 200.0
TLS3_k127_4855915_4 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000001295 185.0
TLS3_k127_4855915_5 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000242 123.0
TLS3_k127_4855915_6 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000006729 107.0
TLS3_k127_4855915_7 Sulfurtransferase TusA - - - 0.0000000000000000000003952 98.0
TLS3_k127_4855915_8 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000001663 96.0
TLS3_k127_4855915_9 PFAM Bacterial regulatory protein, arsR family - - - 0.00000000000001111 79.0
TLS3_k127_4860312_0 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 424.0
TLS3_k127_4860312_1 carbohydrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 399.0
TLS3_k127_4860312_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005206 240.0
TLS3_k127_4860312_3 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000009827 188.0
TLS3_k127_4860312_4 Branched-chain amino acid transport system / permease component K10440,K10441 - 3.6.3.17 0.000000000000000000000000000136 117.0
TLS3_k127_4868026_0 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000001133 220.0
TLS3_k127_4868026_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000004236 182.0
TLS3_k127_4868026_2 Probable molybdopterin binding domain - - - 0.0000000000000000000004614 101.0
TLS3_k127_4875304_0 AAA domain - - - 0.00000000000000000000000000001164 137.0
TLS3_k127_4875304_1 EamA-like transporter family - - - 0.0000000000000000001859 97.0
TLS3_k127_4875304_2 Calcineurin-like phosphoesterase K03547 - - 0.0000002031 60.0
TLS3_k127_4882841_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 1.265e-316 1001.0
TLS3_k127_4882841_1 Glycosyl hydrolases family 25 K07273 - - 0.000000000000000000000000004209 127.0
TLS3_k127_4882841_2 ABC-type Fe3 transport system, periplasmic component - - - 0.00000000000000000006315 94.0
TLS3_k127_4916292_0 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 7.377e-233 743.0
TLS3_k127_4916292_1 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000007057 66.0
TLS3_k127_4918026_0 dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 571.0
TLS3_k127_4918026_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001079 262.0
TLS3_k127_4918026_2 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000000000000000000000001634 220.0
TLS3_k127_4918026_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000005756 193.0
TLS3_k127_4918026_4 Sensory histidine kinase in two-component regulatory system with KdpE K07646 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0008134,GO:0008150,GO:0008152,GO:0009593,GO:0009605,GO:0009628,GO:0009651,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031668,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051606,GO:0051716,GO:0065007,GO:0071214,GO:0071470,GO:0071472,GO:0071496,GO:0071704,GO:0071944,GO:0104004,GO:0140096,GO:1901564 2.7.13.3 0.000000000000002187 78.0
TLS3_k127_4918026_5 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000000000001646 78.0
TLS3_k127_4934818_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 498.0
TLS3_k127_4934818_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 483.0
TLS3_k127_4934818_2 Pfam:DUF2029 - - - 0.000000000000000000000000000000000001897 159.0
TLS3_k127_4934818_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000007766 103.0
TLS3_k127_4934818_4 alginic acid biosynthetic process - - - 0.0000351 54.0
TLS3_k127_495321_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 462.0
TLS3_k127_495321_1 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000004194 115.0
TLS3_k127_497074_0 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000003395 228.0
TLS3_k127_497074_1 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000734 205.0
TLS3_k127_497074_2 Psort location CytoplasmicMembrane, score K12132 - 2.7.11.1 0.0000000000000000000000000009281 132.0
TLS3_k127_497074_3 amino acid transport K02030 - - 0.00000000000000000004251 107.0
TLS3_k127_4997032_0 D-galactarate dehydratase Altronate K01685,K01708 - 4.2.1.42,4.2.1.7 1.373e-231 726.0
TLS3_k127_4997032_1 Alpha amylase, catalytic domain K21350 - 2.4.1.329 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 484.0
TLS3_k127_4997032_2 Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 364.0
TLS3_k127_4997032_3 mannitol metabolic process K00009,K00041 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.17,1.1.1.58 0.0000000000000000000000000000000000001179 147.0
TLS3_k127_5028544_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 507.0
TLS3_k127_5028544_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000001248 141.0
TLS3_k127_5028544_2 LemA family K03744 - - 0.000000000000005324 78.0
TLS3_k127_5028544_3 Preprotein translocase SecG subunit K03075 - - 0.0000000001828 65.0
TLS3_k127_5028544_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000001123 61.0
TLS3_k127_5037990_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 580.0
TLS3_k127_5037990_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001898 270.0
TLS3_k127_5037990_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000001186 185.0
TLS3_k127_5037990_3 MgtC family K07507 - - 0.00000000000000000000000000000000005125 143.0
TLS3_k127_5037990_4 transcriptional regulator - - - 0.000000000000000000000000000000001805 136.0
TLS3_k127_5083410_0 PFAM PfkB domain protein K03338 - 2.7.1.92 0.000000000000000000000000000000000000000000000000000000000000001261 235.0
TLS3_k127_5083410_1 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000208 206.0
TLS3_k127_5083410_3 - - - - 0.000000000000001944 88.0
TLS3_k127_5083410_4 DeoC/LacD family aldolase K01671 - 4.1.2.57 0.000000000000004688 77.0
TLS3_k127_5097277_0 ABC transporter - - - 0.00000000000000000000000000000000000000002971 174.0
TLS3_k127_5097277_1 DNA-binding transcription factor activity K03710 - - 0.0000000000000000000000224 107.0
TLS3_k127_5097277_2 ABC transporter - - - 0.000000000000000000001169 101.0
TLS3_k127_5104180_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 374.0
TLS3_k127_5104180_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000002456 166.0
TLS3_k127_5105876_0 UbiC transcription regulator-associated domain protein K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003989 254.0
TLS3_k127_5105876_1 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000009777 224.0
TLS3_k127_5105876_2 N-acetylglucosamine kinase activity K18676 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 0.000000000000000000000000000000000000000000000000000000000002006 216.0
TLS3_k127_5105876_3 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000000002138 178.0
TLS3_k127_5117283_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 356.0
TLS3_k127_5117283_1 ABC-type multidrug transport system ATPase component K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 304.0
TLS3_k127_5117283_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000001276 233.0
TLS3_k127_5117283_3 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000000000000000005972 167.0
TLS3_k127_5117283_4 Branched-chain amino acid permease - - - 0.000000000000000000004512 109.0
TLS3_k127_5188527_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 595.0
TLS3_k127_5188527_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 395.0
TLS3_k127_5188527_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000972 213.0
TLS3_k127_5188527_3 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000223 131.0
TLS3_k127_5188527_4 YbbR-like protein - - - 0.0000001139 65.0
TLS3_k127_5188527_5 COG0457 FOG TPR repeat - - - 0.0003224 51.0
TLS3_k127_5210628_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 494.0
TLS3_k127_5210628_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 329.0
TLS3_k127_5210628_2 SMART Peptidoglycan-binding LysM - - - 0.0000000000000000000000000133 125.0
TLS3_k127_5210628_3 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000001909 74.0
TLS3_k127_5220521_0 COG2873 O-acetylhomoserine sulfhydrylase K01738,K01740 - 2.5.1.47,2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 609.0
TLS3_k127_5220521_1 NMT1-like family K02051,K15553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 440.0
TLS3_k127_5220521_2 Binding-protein-dependent transport system inner membrane component K15554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 367.0
TLS3_k127_5220521_3 COG2873 O-acetylhomoserine sulfhydrylase K01738,K01740 - 2.5.1.47,2.5.1.49 0.0000000000000000000000000000000000000000000001356 190.0
TLS3_k127_5228106_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 373.0
TLS3_k127_5228106_1 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003033 282.0
TLS3_k127_5228106_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000001823 251.0
TLS3_k127_5237175_0 Heat shock 70 kDa protein K04043 - - 9.874e-272 849.0
TLS3_k127_5237175_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 405.0
TLS3_k127_5237175_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008731 361.0
TLS3_k127_5237175_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000986 267.0
TLS3_k127_5237175_4 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000008122 252.0
TLS3_k127_5237175_5 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.000000000000000000000000000000000000000000000000000000000000001687 226.0
TLS3_k127_5237175_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000001421 220.0
TLS3_k127_5237175_7 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.000000000000000000000000000000000000000000000000000000003553 209.0
TLS3_k127_5237175_8 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000005445 158.0
TLS3_k127_5237175_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000000001096 137.0
TLS3_k127_5239589_0 Uridine phosphorylase K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000001257 217.0
TLS3_k127_5239589_1 - - - - 0.0000000000001616 72.0
TLS3_k127_5239589_2 endonuclease exonuclease phosphatase K07004 - - 0.000202 54.0
TLS3_k127_5246518_0 Transcriptional regulator sugar kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 445.0
TLS3_k127_5246518_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03805,K03981 - 5.3.4.1 0.000000000003032 71.0
TLS3_k127_5246518_2 Domain of unknown function (DUF202) K00389 - - 0.000000000003067 74.0
TLS3_k127_5255969_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 329.0
TLS3_k127_5255969_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000001912 195.0
TLS3_k127_5255969_2 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000003241 122.0
TLS3_k127_5257908_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001231 283.0
TLS3_k127_5257908_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000006438 180.0
TLS3_k127_5257908_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000009904 174.0
TLS3_k127_5257908_3 Sulfotransferase family - - - 0.000000000000000000000000000000000000002833 163.0
TLS3_k127_5257908_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000001871 115.0
TLS3_k127_5257908_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000003249 114.0
TLS3_k127_5266402_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001016 298.0
TLS3_k127_5266402_1 pyridoxamine 5-phosphate - - - 0.00000000000000000004118 98.0
TLS3_k127_5266402_2 COG0739 Membrane proteins related to metalloendopeptidases K21472 - - 0.0005883 50.0
TLS3_k127_5295694_0 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 562.0
TLS3_k127_5295694_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000001531 266.0
TLS3_k127_5295694_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000009188 115.0
TLS3_k127_5295694_3 - - - - 0.00000000000000000000003896 110.0
TLS3_k127_5301149_0 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000537 207.0
TLS3_k127_5301149_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000004982 175.0
TLS3_k127_5301149_2 Hydrogenase nickel incorporation protein hypA K04651 - - 0.00000000000001871 77.0
TLS3_k127_5301149_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000009544 57.0
TLS3_k127_5327458_0 Family 4 glycosyl hydrolase K01222,K07406 - 3.2.1.22,3.2.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 533.0
TLS3_k127_5327458_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 419.0
TLS3_k127_5327458_10 N-acetylglucosamine kinase activity - - - 0.000000000000000000000000000000000000000000000346 192.0
TLS3_k127_5327458_11 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000005581 130.0
TLS3_k127_5327458_12 Low affinity iron permease - - - 0.00000000000000000000000000002995 122.0
TLS3_k127_5327458_2 TOBE domain K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 357.0
TLS3_k127_5327458_3 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 338.0
TLS3_k127_5327458_4 ABC transporter (Permease) K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 339.0
TLS3_k127_5327458_5 Sugar ABC transporter substrate-binding protein K10117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 309.0
TLS3_k127_5327458_6 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001002 288.0
TLS3_k127_5327458_7 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004973 288.0
TLS3_k127_5327458_8 PFAM binding-protein-dependent transport systems inner membrane component K10119 - - 0.000000000000000000000000000000000000000000000000000000000000000000001836 256.0
TLS3_k127_5327458_9 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000006827 214.0
TLS3_k127_5337277_0 PFAM Mandelate racemase muconate lactonizing K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 563.0
TLS3_k127_5337277_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 384.0
TLS3_k127_5337277_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 334.0
TLS3_k127_5337277_3 KR domain - - - 0.0003852 45.0
TLS3_k127_5349013_0 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 433.0
TLS3_k127_5349013_1 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 352.0
TLS3_k127_5349013_10 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000008452 152.0
TLS3_k127_5349013_11 - - - - 0.00000000000000000000000000000001189 138.0
TLS3_k127_5349013_12 Transport permease protein K01992,K09690,K09692 - - 0.00000000000000000000000002036 121.0
TLS3_k127_5349013_13 Domain of unknown function (DU1801) - - - 0.000000000000000000004182 102.0
TLS3_k127_5349013_14 PPIC-type PPIASE domain K01802,K03769 - 5.2.1.8 0.000000000001529 81.0
TLS3_k127_5349013_15 Transglycosylase associated protein - - - 0.000000007106 60.0
TLS3_k127_5349013_16 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00004625 56.0
TLS3_k127_5349013_2 ATP-grasp domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 346.0
TLS3_k127_5349013_3 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 312.0
TLS3_k127_5349013_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000032 269.0
TLS3_k127_5349013_5 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000002525 254.0
TLS3_k127_5349013_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001378 252.0
TLS3_k127_5349013_7 TIGRFAM MazG family protein K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000005466 248.0
TLS3_k127_5349013_8 ABC transporter K01990,K09691,K09693 - 3.6.3.40 0.0000000000000000000000000000000000000000000000000000000004195 215.0
TLS3_k127_5349013_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000001098 184.0
TLS3_k127_5365302_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 530.0
TLS3_k127_5365302_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 303.0
TLS3_k127_5365302_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000003898 154.0
TLS3_k127_5365302_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000004248 56.0
TLS3_k127_5370282_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 299.0
TLS3_k127_5370282_1 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K00059 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.100 0.000000000000000000000000000000000000000000000000000000001177 212.0
TLS3_k127_5370282_2 beta-lactamase domain protein K13075 - 3.1.1.81 0.00000000000000000000000000000000000004609 154.0
TLS3_k127_5370282_3 Transcriptional regulator K22293 - - 0.000000000000000001386 96.0
TLS3_k127_5370282_4 Protein of unknown function (DUF861) - - - 0.0002007 52.0
TLS3_k127_5371502_0 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000406 211.0
TLS3_k127_5371502_1 MoaE protein K03635,K03636,K03637,K03752,K21142 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.77,2.8.1.12,4.6.1.17 0.00000000000000000000000000000000000000004345 174.0
TLS3_k127_5405943_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 406.0
TLS3_k127_5405943_1 Glucose inhibited division protein A K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 397.0
TLS3_k127_5405943_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007019 290.0
TLS3_k127_5405943_3 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000009828 224.0
TLS3_k127_5405943_4 3H domain K07105 - - 0.0000000000000000000000000000000000003916 147.0
TLS3_k127_5405943_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02033 - - 0.000000000000000000000006309 115.0
TLS3_k127_5432238_0 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 436.0
TLS3_k127_5432238_1 Penicillin binding protein transpeptidase domain K05364 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000007443 246.0
TLS3_k127_5432238_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000008377 73.0
TLS3_k127_5448597_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000009477 228.0
TLS3_k127_5448597_1 PIN domain - - - 0.000000000000000000000000000000005308 136.0
TLS3_k127_5448597_2 cyclic nucleotide binding - - - 0.00000000000000000000000000001092 136.0
TLS3_k127_5448597_3 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000003578 83.0
TLS3_k127_5461233_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001717 302.0
TLS3_k127_5461233_1 - K06862 - - 0.00000000000000000000000000000000000000000000000006276 192.0
TLS3_k127_5461233_2 PFAM Acyltransferase - - - 0.00000000000000000000000000000000000000000000000007242 190.0
TLS3_k127_5461233_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000001134 97.0
TLS3_k127_5475218_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000008014 151.0
TLS3_k127_5475218_1 oxidoreductase K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000001354 143.0
TLS3_k127_5475218_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000009954 144.0
TLS3_k127_5475218_3 polysaccharide deacetylase - - - 0.0000000000000000000000000001319 128.0
TLS3_k127_5475218_4 protein conserved in bacteria - - - 0.00000001309 67.0
TLS3_k127_5489155_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 334.0
TLS3_k127_5489155_1 Protein of unknown function (DUF1269) - - - 0.00000000000000000000000000000000000000001601 158.0
TLS3_k127_5489155_2 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000001025 96.0
TLS3_k127_5498087_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.41e-213 682.0
TLS3_k127_5516975_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 427.0
TLS3_k127_5516975_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 357.0
TLS3_k127_5516975_2 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 307.0
TLS3_k127_5516975_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004268 254.0
TLS3_k127_5516975_4 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000003753 241.0
TLS3_k127_5516975_5 - - - - 0.0000000000000000000000000000000000000007906 154.0
TLS3_k127_5516975_6 to Escherichia coli exodeoxyribonuclease X ExoX or b1844 SWALL EXOX_ECOLI (SWALL P76281) (220 aa) fasta scores E() K10857 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.0002999 44.0
TLS3_k127_5516975_7 rod shape-determining protein (MreD) K03571 - - 0.0004576 51.0
TLS3_k127_5547020_0 malic protein domain protein K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 555.0
TLS3_k127_5547020_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003994 288.0
TLS3_k127_5547020_2 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.000000000000001048 81.0
TLS3_k127_5548294_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05565,K14086 - - 9.322e-262 829.0
TLS3_k127_5548294_1 protein involved in exopolysaccharide biosynthesis - - - 1.901e-208 669.0
TLS3_k127_5548294_10 - - - - 0.0002152 45.0
TLS3_k127_5548294_2 carbohydrate transport K17315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 436.0
TLS3_k127_5548294_3 ATPases associated with a variety of cellular activities K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 368.0
TLS3_k127_5548294_4 COG0395 ABC-type sugar transport system, permease component K02026,K17317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 330.0
TLS3_k127_5548294_5 PFAM Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 295.0
TLS3_k127_5548294_6 gntR family K05799 - - 0.000000000000000000000000000000000001264 150.0
TLS3_k127_5548294_7 Na H antiporter MnhB subunit-related protein K05566 - - 0.0000000000000000000000000002623 133.0
TLS3_k127_5548294_8 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000002765 116.0
TLS3_k127_5548294_9 Na H antiporter K05567 - - 0.000000000000000000005729 104.0
TLS3_k127_5549050_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 429.0
TLS3_k127_5549050_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03805,K12228 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001181 256.0
TLS3_k127_5549050_2 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000004334 209.0
TLS3_k127_5549050_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000001621 169.0
TLS3_k127_5556408_0 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 411.0
TLS3_k127_5556408_1 Branched-chain amino acid transport system / permease component K10440,K10560 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 370.0
TLS3_k127_5556408_2 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 317.0
TLS3_k127_5556408_3 mandelate racemase muconate lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 311.0
TLS3_k127_5556408_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004276 271.0
TLS3_k127_5556408_5 KR domain K00019,K00065 - 1.1.1.127,1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000128 209.0
TLS3_k127_5556408_6 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000001718 221.0
TLS3_k127_5556408_7 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.000000000272 64.0
TLS3_k127_5571733_0 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 402.0
TLS3_k127_5571733_1 PFAM Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 315.0
TLS3_k127_5571733_2 Peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005265 278.0
TLS3_k127_5571733_3 Psort location Periplasmic, score K09807 - - 0.000000000000000000000000196 119.0
TLS3_k127_5571733_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000009569 111.0
TLS3_k127_5574329_0 arginine transmembrane transporter activity - - - 0.0000000000000000000000000000000007843 143.0
TLS3_k127_5574329_1 META domain - - - 0.00000000000001217 86.0
TLS3_k127_55884_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.216e-197 637.0
TLS3_k127_55884_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 344.0
TLS3_k127_55884_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000002763 282.0
TLS3_k127_55884_3 elongation factor Tu domain 2 protein K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000001834 232.0
TLS3_k127_55884_4 - - - - 0.00000000000000000000000000000000000007108 150.0
TLS3_k127_5596158_0 von Willebrand factor type A domain - - - 7.902e-214 723.0
TLS3_k127_5596158_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005184 257.0
TLS3_k127_5610561_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 550.0
TLS3_k127_5610561_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 444.0
TLS3_k127_5610561_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 308.0
TLS3_k127_5610561_3 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003295 274.0
TLS3_k127_5610561_4 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001652 269.0
TLS3_k127_5610561_5 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000005572 253.0
TLS3_k127_5610561_6 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000154 258.0
TLS3_k127_5610561_7 acetyltransferase - - - 0.0000000000000000000005244 106.0
TLS3_k127_5630099_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 552.0
TLS3_k127_5630099_1 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 334.0
TLS3_k127_5630099_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000004208 180.0
TLS3_k127_5630099_11 Transcriptional regulator K13641 - - 0.000000000000000000000000000000000000000001435 166.0
TLS3_k127_5630099_12 PFAM regulatory protein AsnC Lrp family K03718 - - 0.000000000000000000000000000000000000000006391 160.0
TLS3_k127_5630099_13 ResB-like family - - - 0.00000000000000000000000000000000000000001984 169.0
TLS3_k127_5630099_14 EAL domain - - - 0.0000000000000000000000000000000000002629 159.0
TLS3_k127_5630099_15 Membrane - - - 0.00000000000009461 80.0
TLS3_k127_5630099_2 Aldo/keto reductase family K00064 - 1.1.1.122 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 332.0
TLS3_k127_5630099_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01740,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 321.0
TLS3_k127_5630099_4 Amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 304.0
TLS3_k127_5630099_5 Domain of unknown function (DUF4432) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 293.0
TLS3_k127_5630099_6 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009287 268.0
TLS3_k127_5630099_7 xylulokinase activity K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000003141 266.0
TLS3_k127_5630099_8 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000004015 251.0
TLS3_k127_5630099_9 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.000000000000000000000000000000000000000000000000000000000000002399 233.0
TLS3_k127_5694159_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1142.0
TLS3_k127_5694159_1 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 332.0
TLS3_k127_5694159_10 Copper binding proteins, plastocyanin/azurin family - - - 0.00003024 47.0
TLS3_k127_5694159_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 330.0
TLS3_k127_5694159_3 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 314.0
TLS3_k127_5694159_4 Belongs to the proline racemase family K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 304.0
TLS3_k127_5694159_5 Transcriptional regulator sugar kinase K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000299 250.0
TLS3_k127_5694159_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000001239 241.0
TLS3_k127_5694159_7 ChrA protein K07240 - - 0.000000000000000000000000000000000000003166 153.0
TLS3_k127_5694159_8 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000002229 121.0
TLS3_k127_5694159_9 Met-10+ like-protein - - - 0.000000000000006229 89.0
TLS3_k127_5749081_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.919e-225 715.0
TLS3_k127_5749081_1 - - - - 0.0000000000000000000004194 106.0
TLS3_k127_5754106_0 chorismate binding enzyme K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000002164 226.0
TLS3_k127_5754106_1 alpha-galactosidase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000007115 166.0
TLS3_k127_5754106_2 Protein of unknown function (DUF2630) - - - 0.0000000001309 65.0
TLS3_k127_5780918_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 459.0
TLS3_k127_5780918_1 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01911 - 6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 329.0
TLS3_k127_5780918_2 chorismate binding enzyme K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002399 283.0
TLS3_k127_5780918_3 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000002062 255.0
TLS3_k127_5780918_4 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000006413 232.0
TLS3_k127_5780918_5 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.000000000000000000000000000000000000000000000000002827 196.0
TLS3_k127_5780918_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000005814 185.0
TLS3_k127_5780918_7 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.000000000000000000000000000000000000000002836 156.0
TLS3_k127_5780918_8 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) - - - 0.0000000000000000000000000000001647 143.0
TLS3_k127_5784333_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000001247 189.0
TLS3_k127_5784333_1 Galactose oxidase, central domain K08282 - 2.7.11.1 0.00000006547 64.0
TLS3_k127_5786685_0 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 419.0
TLS3_k127_5786685_1 Amidohydrolase family K01487 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008892,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0016814,GO:0018756,GO:0019239,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046098,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 298.0
TLS3_k127_5786685_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000003829 174.0
TLS3_k127_5790939_0 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 442.0
TLS3_k127_5790939_1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 402.0
TLS3_k127_5790939_2 PFAM DoxX family protein K16937 - 1.8.5.2 0.00000000000000000000000000000000000000000000000000000000000001938 224.0
TLS3_k127_5790939_3 Transmembrane secretion effector - - - 0.000001114 55.0
TLS3_k127_5808852_0 Amidohydrolase family K01465,K06015 - 3.5.1.81,3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 513.0
TLS3_k127_5808852_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 475.0
TLS3_k127_5808852_2 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008474 278.0
TLS3_k127_5808852_3 FMN-dependent dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.00000000000000000000000000000000000000000000000000000000000008872 232.0
TLS3_k127_5808852_4 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000006136 225.0
TLS3_k127_5808852_5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058,K04496 - 1.1.1.399,1.1.1.95 0.0000000000000000000000001504 113.0
TLS3_k127_5812321_0 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 294.0
TLS3_k127_5812321_1 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000008713 235.0
TLS3_k127_5812321_2 TPM domain - - - 0.000000000000000000000000000000000000000000000000000000003459 226.0
TLS3_k127_5812321_3 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000001059 194.0
TLS3_k127_5812321_4 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000144 117.0
TLS3_k127_5812321_5 RHS Repeat - - - 0.0000000001135 68.0
TLS3_k127_5816344_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 539.0
TLS3_k127_5816344_1 Amylo-alpha-1,6-glucosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 485.0
TLS3_k127_5816344_2 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000002288 230.0
TLS3_k127_5816344_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000004683 225.0
TLS3_k127_5816344_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000012 132.0
TLS3_k127_5816344_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000002541 133.0
TLS3_k127_5816344_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000002007 63.0
TLS3_k127_5816344_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000003652 51.0
TLS3_k127_5839116_0 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006951 292.0
TLS3_k127_5839116_1 NAD-dependent epimerase dehydratase K07071 - - 0.0000000000000000000000000000000000000000000000000000000002561 214.0
TLS3_k127_5839116_2 YndJ-like protein - - - 0.000000003988 68.0
TLS3_k127_5844954_0 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 257.0
TLS3_k127_5844954_1 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.0000000000000000000000001375 122.0
TLS3_k127_5844954_2 Histidine kinase-like ATPases K07777 - 2.7.13.3 0.000000000000000000000008977 113.0
TLS3_k127_5844954_3 Flp Fap pilin component - - - 0.0003215 45.0
TLS3_k127_5845330_0 belongs to the thioredoxin family K20543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 541.0
TLS3_k127_5845330_1 Xaa-Pro aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 501.0
TLS3_k127_5845330_2 ABC transporter substrate-binding protein K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 386.0
TLS3_k127_5845330_3 ABC-type sugar transport system, ATPase component K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 290.0
TLS3_k127_5861596_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 497.0
TLS3_k127_5861596_1 Acyltransferase family - - - 0.0000000000000000000000000000000001339 152.0
TLS3_k127_5861596_2 this gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.0000009656 62.0
TLS3_k127_5863349_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0 1139.0
TLS3_k127_5863349_1 TrkA-N domain K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 343.0
TLS3_k127_5867198_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 603.0
TLS3_k127_5884250_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 468.0
TLS3_k127_5884250_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 298.0
TLS3_k127_5884250_2 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000008385 134.0
TLS3_k127_5884250_3 Pfam:DUF2029 - - - 0.00000000000000000000000000008755 123.0
TLS3_k127_5884250_4 Protein of unknown function (DUF971) - - - 0.0000000000000000000000007498 115.0
TLS3_k127_5890067_0 )-transporter K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 383.0
TLS3_k127_5890067_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 365.0
TLS3_k127_5890067_10 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000003161 134.0
TLS3_k127_5890067_2 periplasmic binding protein LacI transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 334.0
TLS3_k127_5890067_3 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 324.0
TLS3_k127_5890067_4 ABC-type sugar transport system, permease component K10119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001348 263.0
TLS3_k127_5890067_5 ABC-type sugar transport system, periplasmic component K10117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002816 265.0
TLS3_k127_5890067_6 Binding-protein-dependent transport system inner membrane component K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005311 248.0
TLS3_k127_5890067_7 Phosphorylase superfamily K00772,K03784 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000004142 225.0
TLS3_k127_5890067_8 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000000000000002921 218.0
TLS3_k127_5890067_9 ABC transporter (Permease) K05846 - - 0.00000000000000000000000000000000000000000000000000122 196.0
TLS3_k127_5890359_0 daunorubicin resistance ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 426.0
TLS3_k127_5890359_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 437.0
TLS3_k127_5890359_2 transferase K07749,K18702 - 2.8.3.16,2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 417.0
TLS3_k127_5890359_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 309.0
TLS3_k127_5890359_4 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 304.0
TLS3_k127_5890359_5 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005377 290.0
TLS3_k127_5890359_6 PFAM Pyridoxal-dependent decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002233 266.0
TLS3_k127_5890359_7 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000001478 237.0
TLS3_k127_5890359_8 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000002162 78.0
TLS3_k127_5916806_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 459.0
TLS3_k127_5916806_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 336.0
TLS3_k127_5916806_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 316.0
TLS3_k127_5916806_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 306.0
TLS3_k127_5916806_4 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000001086 192.0
TLS3_k127_5916806_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000004311 151.0
TLS3_k127_5916806_6 acetyltransferase - - - 0.00000000000000002198 92.0
TLS3_k127_5927498_0 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004823 249.0
TLS3_k127_5927498_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000009037 233.0
TLS3_k127_5927498_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000002049 214.0
TLS3_k127_5927498_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.00000000000000000000000002016 113.0
TLS3_k127_5927498_4 response to heat K03668,K09914 - - 0.0000000000006252 79.0
TLS3_k127_5927498_5 - - - - 0.00000005589 60.0
TLS3_k127_5935993_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00823 - 2.6.1.19,4.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 488.0
TLS3_k127_5935993_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000166 230.0
TLS3_k127_5935993_2 CARDB - - - 0.000000000000000000000000000000000000000000000000000000000000001828 240.0
TLS3_k127_5935993_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000002242 230.0
TLS3_k127_5935993_4 VanZ like family - - - 0.00000001913 63.0
TLS3_k127_5942278_0 Belongs to the HpcH HpaI aldolase family K01630,K02510,K12660 - 4.1.2.20,4.1.2.52,4.1.2.53 0.000000000000000000000000000000000000000000000003189 182.0
TLS3_k127_5942278_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000001793 59.0
TLS3_k127_5945912_0 Pfam:DUF2029 - - - 0.00000000000000000000000000000000000000000008619 173.0
TLS3_k127_5945912_1 Pfam:DUF2029 - - - 0.00000000000000000000000000000001074 141.0
TLS3_k127_5945912_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000001647 67.0
TLS3_k127_5947396_0 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 460.0
TLS3_k127_5947396_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 434.0
TLS3_k127_5947396_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009617 308.0
TLS3_k127_5947396_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 309.0
TLS3_k127_5947396_4 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000004677 255.0
TLS3_k127_5947396_5 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000489 237.0
TLS3_k127_5947396_6 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000281 209.0
TLS3_k127_5947396_7 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000007153 141.0
TLS3_k127_5947396_8 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000001689 137.0
TLS3_k127_597569_0 Metallo-beta-lactamase superfamily - - - 3.117e-207 661.0
TLS3_k127_597569_1 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 377.0
TLS3_k127_597569_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 364.0
TLS3_k127_597569_3 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 347.0
TLS3_k127_597569_4 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 318.0
TLS3_k127_597569_5 water channel activity K02440,K06188 - - 0.00000000000000000000000000000000000000000000000000000000003089 219.0
TLS3_k127_597569_6 ACT domain - - - 0.00000000000000000000000000000000000000005033 160.0
TLS3_k127_597569_7 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000001378 156.0
TLS3_k127_597569_8 Belongs to the glycosyl hydrolase 31 family - - - 0.00000000000000000000003887 100.0
TLS3_k127_6010938_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.608e-233 731.0
TLS3_k127_6010938_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 362.0
TLS3_k127_6010938_2 Transcriptional Regulator AraC Family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 300.0
TLS3_k127_6010938_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000001283 214.0
TLS3_k127_6010938_4 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000000000000001946 189.0
TLS3_k127_6030115_0 Haloacid dehalogenase-like hydrolase K07025,K20862 - 3.1.3.102,3.1.3.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 350.0
TLS3_k127_6030115_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 286.0
TLS3_k127_6030115_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0004135 46.0
TLS3_k127_6060025_0 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 417.0
TLS3_k127_6060025_1 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 308.0
TLS3_k127_6060025_2 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005501 287.0
TLS3_k127_6060025_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000003283 265.0
TLS3_k127_6060025_4 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K04496 - - 0.0000000000000000000000000000000000000000000000000000000001527 218.0
TLS3_k127_6060025_5 gntR family - - - 0.00000000000000000000000000000000000000001799 161.0
TLS3_k127_6060025_6 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000001263 109.0
TLS3_k127_6060025_7 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.0000003013 54.0
TLS3_k127_6092767_0 ABC-type sugar transport system, ATPase component K10441 - 3.6.3.17 9.709e-202 644.0
TLS3_k127_6092767_1 AP endonuclease family 2 C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 478.0
TLS3_k127_6092767_10 DeoC/LacD family aldolase K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 297.0
TLS3_k127_6092767_11 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000009763 252.0
TLS3_k127_6092767_12 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003586 255.0
TLS3_k127_6092767_13 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443,K16786,K16787 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000005387 247.0
TLS3_k127_6092767_14 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000007869 196.0
TLS3_k127_6092767_15 Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K02805,K13017,K18653 - 2.6.1.104,2.6.1.59,2.6.1.98 0.00000000000000000000000000000000000000000002618 170.0
TLS3_k127_6092767_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 492.0
TLS3_k127_6092767_3 Periplasmic binding protein domain K02058,K10439,K17213 GO:0003674,GO:0005215,GO:0005488,GO:0005534,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015749,GO:0015757,GO:0016020,GO:0016021,GO:0022857,GO:0030246,GO:0030288,GO:0030313,GO:0031224,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0044425,GO:0044464,GO:0048029,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 448.0
TLS3_k127_6092767_4 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 401.0
TLS3_k127_6092767_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 390.0
TLS3_k127_6092767_6 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 388.0
TLS3_k127_6092767_7 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 374.0
TLS3_k127_6092767_8 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 371.0
TLS3_k127_6092767_9 protein containing SIS (Sugar isomerase) phosphosugar binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 312.0
TLS3_k127_6140392_0 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000001935 220.0
TLS3_k127_6140392_1 DinB family - - - 0.0000000000000000000000000000009216 131.0
TLS3_k127_6140392_2 - - - - 0.00000002101 59.0
TLS3_k127_6143720_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 297.0
TLS3_k127_6143720_1 YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000000000000000000000000000000001359 218.0
TLS3_k127_6143720_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000002231 168.0
TLS3_k127_6143720_3 - - - - 0.00000000000000000000000000006958 118.0
TLS3_k127_6143720_4 SMART Peptidoglycan-binding LysM - - - 0.0000000000000000000000000002577 130.0
TLS3_k127_6149808_0 von Willebrand factor type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 571.0
TLS3_k127_6149808_1 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 445.0
TLS3_k127_6149808_10 Glycosyl hydrolase family 66 K05988 - 3.2.1.11 0.0000000000000000000000000000000000000000000000000006294 210.0
TLS3_k127_6149808_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000004575 140.0
TLS3_k127_6149808_2 Extracellular solute-binding protein K15770 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 309.0
TLS3_k127_6149808_3 ABC transporter permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 306.0
TLS3_k127_6149808_4 gluconolactonase activity K01053,K02352 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000332 311.0
TLS3_k127_6149808_5 transmembrane transport K02025,K05814,K10109,K10118,K15771,K17242,K17245 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005039 269.0
TLS3_k127_6149808_6 Glycosyl hydrolases family 15 K22308 - 3.2.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000001748 265.0
TLS3_k127_6149808_7 Branched-chain amino acid transport system / permease component K10440,K17206 - - 0.0000000000000000000000000000000000000000000000000000000000000000002048 247.0
TLS3_k127_6149808_8 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003242 245.0
TLS3_k127_6149808_9 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000006992 212.0
TLS3_k127_618810_0 COG COG0371 Glycerol dehydrogenase and related enzymes Energy production and conversion K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 332.0
TLS3_k127_618810_1 Belongs to the HAD-like hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004228 258.0
TLS3_k127_618810_2 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000001001 211.0
TLS3_k127_618810_3 2-Nitropropane dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000009887 219.0
TLS3_k127_618810_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000005258 211.0
TLS3_k127_618810_5 DNA-binding transcription factor activity K03710 - - 0.000000000000000000000000000000000000000000000001384 183.0
TLS3_k127_618810_6 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000003684 172.0
TLS3_k127_618810_8 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.0000000000000000000000000000000001445 150.0
TLS3_k127_6216381_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000002352 102.0
TLS3_k127_6216381_1 lysyltransferase activity K07027 - - 0.000000000000000005418 97.0
TLS3_k127_6226498_0 Alpha amylase, catalytic domain - - - 8.28e-270 884.0
TLS3_k127_6226498_1 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 420.0
TLS3_k127_6226498_10 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.000000000000000000000000000002404 138.0
TLS3_k127_6226498_11 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.00000000000000004674 86.0
TLS3_k127_6226498_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 389.0
TLS3_k127_6226498_3 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 386.0
TLS3_k127_6226498_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 309.0
TLS3_k127_6226498_5 Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 309.0
TLS3_k127_6226498_6 Heme oxygenase K21480 - 1.14.15.20 0.00000000000000000000000000000000000000000000000000000009375 202.0
TLS3_k127_6226498_7 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000001271 169.0
TLS3_k127_6226498_8 NYN domain - - - 0.000000000000000000000000000000000003097 157.0
TLS3_k127_6226498_9 Lysyl oxidase - - - 0.00000000000000000000000000000000001456 147.0
TLS3_k127_6239162_0 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 387.0
TLS3_k127_6239162_1 Periplasmic binding proteins and sugar binding domain of LacI family K10552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 383.0
TLS3_k127_6239162_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 359.0
TLS3_k127_6239162_3 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 313.0
TLS3_k127_6239162_4 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000831 312.0
TLS3_k127_6239162_5 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.000000000000000000000000000000000003345 139.0
TLS3_k127_6286283_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 440.0
TLS3_k127_6286283_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 415.0
TLS3_k127_6286283_2 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 405.0
TLS3_k127_6286283_3 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 377.0
TLS3_k127_6286283_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 342.0
TLS3_k127_6286283_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002036 253.0
TLS3_k127_6286283_6 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000001564 241.0
TLS3_k127_6286283_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000001621 74.0
TLS3_k127_6299867_0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 297.0
TLS3_k127_6299867_1 PFAM FAD dependent oxidoreductase K00301 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000391 203.0
TLS3_k127_6299867_2 Amino-transferase class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000732 189.0
TLS3_k127_6304929_0 PFAM ABC transporter K02056,K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 499.0
TLS3_k127_6304929_1 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 351.0
TLS3_k127_6304929_2 ABC-type sugar transport system periplasmic component-like protein K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009263 263.0
TLS3_k127_6304929_3 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000001853 247.0
TLS3_k127_6325712_0 Histidine kinase - - - 0.00000000000002031 86.0
TLS3_k127_6325712_1 Bacterial extracellular solute-binding protein K10232 - - 0.0000000003452 63.0
TLS3_k127_6339355_0 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 378.0
TLS3_k127_6339355_1 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003133 272.0
TLS3_k127_6339355_2 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000001252 233.0
TLS3_k127_6339355_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000005356 170.0
TLS3_k127_6339355_4 TIGRFAM LPXTG-motif cell wall anchor domain - - - 0.0000000000000000000000000000000002838 143.0
TLS3_k127_6339355_5 AdoMet dependent proline di-methyltransferase - - - 0.0000000000000000000002287 110.0
TLS3_k127_6339355_6 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000006761 97.0
TLS3_k127_6347911_0 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 601.0
TLS3_k127_6347911_1 Domain of unknown function (DUF1905) - - - 0.0000000000000000000000000000000001559 134.0
TLS3_k127_6347911_2 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000005321 76.0
TLS3_k127_6347911_3 ATP-grasp enzyme - - - 0.00001687 55.0
TLS3_k127_6356812_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 423.0
TLS3_k127_6356812_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 313.0
TLS3_k127_6356812_2 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.00000000000000000000000000000000000000000000000000000002866 208.0
TLS3_k127_6356812_3 Binding-protein-dependent transport system inner membrane component K02026,K10229 - - 0.00000000000000000000000000000000000000000000000000002283 210.0
TLS3_k127_6356812_4 RpiR family transcriptional regulator - - - 0.0000000000000000000000000000000000000009028 164.0
TLS3_k127_6356812_5 isomerase activity K00820 - 2.6.1.16 0.000000000000000000000000006127 128.0
TLS3_k127_6384703_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 8.788e-258 814.0
TLS3_k127_6384703_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000007332 158.0
TLS3_k127_6384703_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000001176 92.0
TLS3_k127_6391429_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 1.957e-265 845.0
TLS3_k127_6391429_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000002315 111.0
TLS3_k127_6391429_2 PFAM MerR family regulatory protein K13640 - - 0.000000000000000000001563 99.0
TLS3_k127_6398965_0 PFAM major facilitator superfamily MFS_1 K08167 - - 4.124e-198 631.0
TLS3_k127_6398965_1 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K02029 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 320.0
TLS3_k127_6398965_2 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 295.0
TLS3_k127_6398965_3 Tetratrico peptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000531 222.0
TLS3_k127_6398965_4 Bacterial periplasmic substrate-binding proteins K02030,K02424,K17073 - - 0.000000000000000000000000000000000000000000000000000000000000006768 228.0
TLS3_k127_6422125_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1247.0
TLS3_k127_6422125_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 304.0
TLS3_k127_6437945_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 471.0
TLS3_k127_6437945_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 426.0
TLS3_k127_6437945_2 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 347.0
TLS3_k127_6442754_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.761e-253 800.0
TLS3_k127_6442754_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.879e-195 632.0
TLS3_k127_6442754_11 EamA-like transporter family - - - 0.00000002064 58.0
TLS3_k127_6442754_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 454.0
TLS3_k127_6442754_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 383.0
TLS3_k127_6442754_4 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000006241 233.0
TLS3_k127_6442754_5 DNA binding domain - - - 0.00000000000000000000000000000004697 130.0
TLS3_k127_6442754_6 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000002424 140.0
TLS3_k127_6442754_7 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000004808 132.0
TLS3_k127_6442754_8 Belongs to the carbohydrate kinase PfkB family - - - 0.0000000000000000000000000008118 124.0
TLS3_k127_6442754_9 ribosomal protein L17 K16193 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000004041 87.0
TLS3_k127_6465015_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 381.0
TLS3_k127_6465015_1 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000006857 53.0
TLS3_k127_6467775_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 590.0
TLS3_k127_6467775_1 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 424.0
TLS3_k127_6467775_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 383.0
TLS3_k127_6467775_3 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 377.0
TLS3_k127_6467775_4 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 350.0
TLS3_k127_6467775_5 F5/8 type C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000007655 240.0
TLS3_k127_6467775_6 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000002246 167.0
TLS3_k127_6467775_7 Protein of unknown function (DUF1622) - - - 0.000000000000000000001554 98.0
TLS3_k127_6499507_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 353.0
TLS3_k127_6499507_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 325.0
TLS3_k127_6529967_0 Acyl transferase domain in polyketide synthase (PKS) enzymes. K16129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 417.0
TLS3_k127_6529967_1 Putative esterase - - - 0.00000000000000000000000000000000006066 150.0
TLS3_k127_6529967_2 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000005659 65.0
TLS3_k127_6538899_0 Flavin containing amine oxidoreductase - - - 1.861e-239 749.0
TLS3_k127_6538899_1 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 433.0
TLS3_k127_6538899_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000009131 246.0
TLS3_k127_6538899_3 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000005933 103.0
TLS3_k127_6538899_4 - - - - 0.000000009584 68.0
TLS3_k127_6548703_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 478.0
TLS3_k127_6548703_1 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 295.0
TLS3_k127_6548703_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000123 278.0
TLS3_k127_6559480_0 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 532.0
TLS3_k127_6559480_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 458.0
TLS3_k127_6559480_2 carbohydrate transport K10117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 308.0
TLS3_k127_6559480_3 KR domain K00216 - 1.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000008334 239.0
TLS3_k127_6559480_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000001266 229.0
TLS3_k127_6559480_5 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000005571 189.0
TLS3_k127_6559480_6 domain, Protein - - - 0.000000000000000000000000000000000000000000005592 186.0
TLS3_k127_6559480_7 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000006141 166.0
TLS3_k127_6559480_8 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000001376 93.0
TLS3_k127_6559480_9 L-rhamnose mutarotase K03534 - 5.1.3.32 0.0000000000003581 74.0
TLS3_k127_6572190_0 Belongs to the D-alanine--D-alanine ligase family K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.0000000000000000000000000000000000000000000000000004787 203.0
TLS3_k127_6572190_1 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000001093 128.0
TLS3_k127_6597028_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.018e-270 862.0
TLS3_k127_6632152_0 peptidase - - - 0.00000000000000000000000000000000002647 144.0
TLS3_k127_6632152_1 glycoside hydrolase family 63 - - - 0.000000000000000000001364 109.0
TLS3_k127_6632152_2 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000005242 101.0
TLS3_k127_6689964_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.492e-257 844.0
TLS3_k127_6689964_1 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000109 259.0
TLS3_k127_6689964_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000005067 188.0
TLS3_k127_6689964_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000005462 169.0
TLS3_k127_6689964_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000007254 98.0
TLS3_k127_6754555_0 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 389.0
TLS3_k127_6754555_1 sugar isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 358.0
TLS3_k127_6754555_2 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 280.0
TLS3_k127_6754555_3 Aminoglycoside phosphotransferase K16146 - 2.7.1.175 0.0000000000000000000000000000000000000000000000000000000000000009287 239.0
TLS3_k127_6783306_0 peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 613.0
TLS3_k127_6783306_1 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003334 286.0
TLS3_k127_6784549_0 PHP domain protein K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 478.0
TLS3_k127_6784549_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 439.0
TLS3_k127_6784549_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 344.0
TLS3_k127_6784549_3 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008039 282.0
TLS3_k127_6784549_4 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000001057 124.0
TLS3_k127_6784549_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000003311 96.0
TLS3_k127_6800157_0 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 384.0
TLS3_k127_6800157_1 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 292.0
TLS3_k127_6800157_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000001854 73.0
TLS3_k127_6800157_3 spore germination - - - 0.00000004823 64.0
TLS3_k127_6838600_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 400.0
TLS3_k127_6838600_1 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000004741 240.0
TLS3_k127_6838600_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000191 151.0
TLS3_k127_6838600_3 Nickel-containing superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.00000000000000000000000000000000000008605 147.0
TLS3_k127_6838600_4 Domain of unknown function (DUF4260) - - - 0.000000000000000000003043 98.0
TLS3_k127_6838600_5 Winged helix DNA-binding domain - - - 0.00000000006087 70.0
TLS3_k127_6838600_6 peptidase - - - 0.000000001065 66.0
TLS3_k127_685734_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000005967 265.0
TLS3_k127_685734_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000003602 136.0
TLS3_k127_6870874_0 Glycosyltransferase family 28 C-terminal domain - - - 3.572e-270 848.0
TLS3_k127_6870874_1 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 453.0
TLS3_k127_6870874_10 xanthine phosphoribosyltransferase activity K00769,K07101 GO:0000310,GO:0003674,GO:0003824,GO:0004422,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0032265,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22 0.0000000000000000000000000000000000000004507 153.0
TLS3_k127_6870874_11 transcriptional regulator - - - 0.00000000000000000000000000000000000006332 151.0
TLS3_k127_6870874_12 Rhodanese Homology Domain - - - 0.000000000000000000000003289 106.0
TLS3_k127_6870874_13 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000004843 92.0
TLS3_k127_6870874_14 COG2040 Homocysteine selenocysteine methylase (S-methylmethionine-dependent) K00547 - 2.1.1.10 0.0001651 54.0
TLS3_k127_6870874_2 Exporter of polyketide antibiotics K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 461.0
TLS3_k127_6870874_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 419.0
TLS3_k127_6870874_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 395.0
TLS3_k127_6870874_5 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 367.0
TLS3_k127_6870874_6 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 357.0
TLS3_k127_6870874_7 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003767 268.0
TLS3_k127_6870874_8 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000006725 172.0
TLS3_k127_6870874_9 EamA-like transporter family - - - 0.00000000000000000000000000000000000000008063 163.0
TLS3_k127_6884323_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 317.0
TLS3_k127_6884323_1 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003081 287.0
TLS3_k127_6884323_2 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000009887 265.0
TLS3_k127_6884323_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000607 164.0
TLS3_k127_6884323_4 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000000000000000005569 158.0
TLS3_k127_6930278_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 341.0
TLS3_k127_6930278_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 304.0
TLS3_k127_6930278_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000521 154.0
TLS3_k127_6930278_3 - - - - 0.00001821 46.0
TLS3_k127_6940797_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.15e-196 628.0
TLS3_k127_6940797_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 490.0
TLS3_k127_6940797_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 440.0
TLS3_k127_6940797_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 417.0
TLS3_k127_6940797_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000006964 216.0
TLS3_k127_6940797_5 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000001864 178.0
TLS3_k127_6940824_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.019e-209 667.0
TLS3_k127_6940824_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000005736 139.0
TLS3_k127_6940824_2 Biotin-requiring enzyme - - - 0.0000000002054 70.0
TLS3_k127_6941701_0 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 578.0
TLS3_k127_6941701_1 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 451.0
TLS3_k127_6941701_2 TOBE domain K02045,K02052 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 423.0
TLS3_k127_6941701_3 Binding-protein-dependent transport system inner membrane component K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 297.0
TLS3_k127_6941701_4 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001065 289.0
TLS3_k127_6941701_5 Transport permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000009183 232.0
TLS3_k127_6941701_6 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000001123 189.0
TLS3_k127_6941701_7 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000002809 145.0
TLS3_k127_695298_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 607.0
TLS3_k127_695298_1 Copper resistance K02351,K07245 - - 0.000000000000000000000000000000000000000000000000000000009238 210.0
TLS3_k127_695298_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000000000005278 178.0
TLS3_k127_695298_3 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000214 162.0
TLS3_k127_6969867_0 hydrolase, TatD family' K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000007184 167.0
TLS3_k127_6969867_1 Acyl-ACP thioesterase - - - 0.0000000000001561 81.0
TLS3_k127_6986599_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 589.0
TLS3_k127_6986599_1 udp-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 473.0
TLS3_k127_6986599_2 Branched-chain amino acid transport system / permease component K02057,K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009764 349.0
TLS3_k127_6986599_3 Branched-chain amino acid transport system / permease component K10440,K17209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 321.0
TLS3_k127_6986599_4 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 312.0
TLS3_k127_6986599_5 Periplasmic binding protein domain K10439 - - 0.0000000000000000002872 87.0
TLS3_k127_7059553_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 347.0
TLS3_k127_7059553_1 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 316.0
TLS3_k127_7061067_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 537.0
TLS3_k127_7061067_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 475.0
TLS3_k127_7061067_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 359.0
TLS3_k127_7061067_3 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002518 288.0
TLS3_k127_7061067_4 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000006699 185.0
TLS3_k127_7061067_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000001424 139.0
TLS3_k127_7061067_6 regulatory protein RecX K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000001626 59.0
TLS3_k127_7069761_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K12952 - - 4.316e-195 638.0
TLS3_k127_7069761_1 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007828 505.0
TLS3_k127_7069761_11 Alpha/beta hydrolase family K07020 - - 0.00000000000000000002129 100.0
TLS3_k127_7069761_13 Universal stress protein - - - 0.00000000004353 69.0
TLS3_k127_7069761_14 ompA family - - - 0.0007383 52.0
TLS3_k127_7069761_2 aminotransferase class I and II K00812,K10907,K14267 - 2.6.1.1,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 481.0
TLS3_k127_7069761_3 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 342.0
TLS3_k127_7069761_4 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000157 278.0
TLS3_k127_7069761_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000003485 244.0
TLS3_k127_7069761_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000003781 224.0
TLS3_k127_7069761_7 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000005931 223.0
TLS3_k127_7069761_8 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000169 217.0
TLS3_k127_7069761_9 - - - - 0.0000000000000000000000001349 121.0
TLS3_k127_709911_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 346.0
TLS3_k127_709911_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001987 270.0
TLS3_k127_709911_10 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000000156 66.0
TLS3_k127_709911_11 beta-lactamase K01286 - 3.4.16.4 0.0001283 47.0
TLS3_k127_709911_2 Serine threonine protein kinase involved in cell cycle control - - - 0.0000000000000000000000000000000000000000000000000000000000000000001246 240.0
TLS3_k127_709911_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001874 214.0
TLS3_k127_709911_4 Iron-storage protein K22336 GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000003643 200.0
TLS3_k127_709911_5 PFAM HhH-GPD family protein - - - 0.00000000000000000000000000000000000000000000002201 176.0
TLS3_k127_709911_6 PAC2 family - - - 0.000000000000000000000000000000000000001901 158.0
TLS3_k127_709911_8 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000000003394 138.0
TLS3_k127_709928_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 361.0
TLS3_k127_709928_1 - - - - 0.0000000000000000000000000000000000000000000000000000000004112 222.0
TLS3_k127_709928_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001883 206.0
TLS3_k127_7105722_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 406.0
TLS3_k127_7105722_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000005459 229.0
TLS3_k127_7105722_2 GAF domain - - - 0.0000000000000000008254 96.0
TLS3_k127_7115537_0 PFAM extracellular solute-binding protein family 1 K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 510.0
TLS3_k127_7115537_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000742 243.0
TLS3_k127_7115537_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000005226 164.0
TLS3_k127_7125514_0 Family of unknown function (DUF5317) - - - 0.000000000000000002379 94.0
TLS3_k127_7125514_1 Putative diguanylate phosphodiesterase - - - 0.0007856 50.0
TLS3_k127_712676_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 588.0
TLS3_k127_712676_1 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000706 222.0
TLS3_k127_712676_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000009981 78.0
TLS3_k127_712676_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 0.000000000006945 70.0
TLS3_k127_7156358_0 Aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 425.0
TLS3_k127_7156358_1 PFAM Lipopolysaccharide kinase (Kdo WaaP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 399.0
TLS3_k127_7156358_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000001483 138.0
TLS3_k127_7156358_3 FCD - - - 0.0000000000000000000000000001764 128.0
TLS3_k127_7156358_4 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000367 81.0
TLS3_k127_7157772_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 503.0
TLS3_k127_7157772_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 346.0
TLS3_k127_7157772_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000003883 184.0
TLS3_k127_7157772_3 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000002449 173.0
TLS3_k127_7170098_0 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000002561 226.0
TLS3_k127_7170098_1 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000000000000000000002771 190.0
TLS3_k127_7170098_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000001562 140.0
TLS3_k127_7170098_3 PFAM biotin lipoyl attachment domain-containing protein - - - 0.000000000000000000000368 102.0
TLS3_k127_7195910_0 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 377.0
TLS3_k127_7195910_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000003333 211.0
TLS3_k127_7195910_2 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000001836 120.0
TLS3_k127_7195910_3 Transcriptional regulator - - - 0.00000000000000000000000364 108.0
TLS3_k127_7195910_4 Pfam:DUF59 - - - 0.00000000002823 68.0
TLS3_k127_7195910_5 Protein of unknown function (DUF433) - - - 0.00003483 55.0
TLS3_k127_7198710_0 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 301.0
TLS3_k127_7198710_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000001579 174.0
TLS3_k127_7198710_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000002302 111.0
TLS3_k127_721368_0 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 368.0
TLS3_k127_721368_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000009719 196.0
TLS3_k127_721368_2 PFAM beta-lactamase domain protein - - - 0.0000000000002416 74.0
TLS3_k127_7214530_0 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 518.0
TLS3_k127_7214530_1 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 464.0
TLS3_k127_7214530_2 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 382.0
TLS3_k127_7214530_3 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001587 287.0
TLS3_k127_7214530_4 Protein tyrosine kinase - - - 0.0000000000000001284 91.0
TLS3_k127_7214530_5 ATP dependent DNA ligase C terminal region - - - 0.0000000123 64.0
TLS3_k127_7214530_6 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0004217 42.0
TLS3_k127_7249723_0 Secretory lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008589 548.0
TLS3_k127_7249723_1 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 488.0
TLS3_k127_7249723_10 Serine aminopeptidase, S33 - - - 0.000000000000000000007263 102.0
TLS3_k127_7249723_11 PFAM regulatory protein, MarR - - - 0.000000000000000002562 94.0
TLS3_k127_7249723_12 Isocitrate/isopropylmalate dehydrogenase K00030,K00031 - 1.1.1.41,1.1.1.42 0.000000002534 63.0
TLS3_k127_7249723_2 SMART Metal-dependent phosphohydrolase, HD region K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 447.0
TLS3_k127_7249723_3 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 357.0
TLS3_k127_7249723_4 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002825 268.0
TLS3_k127_7249723_5 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000002164 244.0
TLS3_k127_7249723_6 Binding-protein-dependent transport system inner membrane component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000001256 254.0
TLS3_k127_7249723_7 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000691 240.0
TLS3_k127_7249723_8 phosphatase activity K05967 - - 0.0000000000000000000000000000000000000000000000000000000002973 209.0
TLS3_k127_7249723_9 PFAM NUDIX domain - - - 0.00000000000000000000000000000000000000329 153.0
TLS3_k127_7253377_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000003745 231.0
TLS3_k127_7253377_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000001737 211.0
TLS3_k127_7253377_2 - - - - 0.00002251 57.0
TLS3_k127_725954_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 581.0
TLS3_k127_725954_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 544.0
TLS3_k127_725954_2 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 407.0
TLS3_k127_725954_3 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000008611 235.0
TLS3_k127_725954_4 type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis - - - 0.000006787 57.0
TLS3_k127_727160_0 Binding-protein-dependent transport system inner membrane component K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 398.0
TLS3_k127_727160_1 PFAM binding-protein-dependent transport systems inner membrane component K10119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 406.0
TLS3_k127_7272729_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 423.0
TLS3_k127_7272729_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 406.0
TLS3_k127_7272729_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 338.0
TLS3_k127_7272729_3 Cytidylate kinase-like family K00945 - 2.7.4.25 0.000000000000000119 93.0
TLS3_k127_7272729_4 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000003694 62.0
TLS3_k127_7272729_5 META domain - - - 0.000004726 58.0
TLS3_k127_7276770_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007108 275.0
TLS3_k127_7276770_1 Ligand-binding protein SH3 K11741 - - 0.0000000000000000000000000000000000000002654 154.0
TLS3_k127_7276770_2 - - - - 0.00000000000005742 81.0
TLS3_k127_7276770_3 - - - - 0.000000002736 63.0
TLS3_k127_7276770_4 Small multidrug resistance protein K03297,K11741 - - 0.0003244 48.0
TLS3_k127_7282422_0 adenosine deaminase K01488,K02029,K21053 - 3.5.4.2,3.5.4.4 0.00000000000000000000000000000000000000000000000000003616 208.0
TLS3_k127_7282422_1 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000002502 159.0
TLS3_k127_7287850_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1108.0
TLS3_k127_7287850_1 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 508.0
TLS3_k127_7287850_2 protein methyltransferase activity K11434,K15984,K20421 - 2.1.1.242,2.1.1.303,2.1.1.319 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 424.0
TLS3_k127_7287850_3 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000001689 192.0
TLS3_k127_7294077_0 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 316.0
TLS3_k127_7294077_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000001812 232.0
TLS3_k127_7294077_2 mannitol metabolic process K00009,K00041 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.17,1.1.1.58 0.0000000000000000000000000000000000000001195 158.0
TLS3_k127_7297953_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 378.0
TLS3_k127_7297953_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000166 229.0
TLS3_k127_7297953_2 PFAM YibE F-like protein - - - 0.0000000000000000000000000000000000000000000000000001555 202.0
TLS3_k127_7297953_3 pyridoxamine 5-phosphate K07006 - - 0.000000000000000000000000000000000000000001626 161.0
TLS3_k127_7321104_0 Alkyl sulfatase dimerisation - - - 2.506e-264 827.0
TLS3_k127_7321104_1 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 467.0
TLS3_k127_7321104_2 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 454.0
TLS3_k127_7321104_3 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001366 260.0
TLS3_k127_7321104_4 sulphate transporter K03321 - - 0.000000000000000000000000000000000001095 145.0
TLS3_k127_7321104_5 sulphate transporter K03321 - - 0.000000000000000000000000004557 118.0
TLS3_k127_7321104_6 Protein of unknown function (DUF1269) - - - 0.00000000000000000000000003716 121.0
TLS3_k127_7321104_7 AI-2E family transporter - - - 0.00000000000000078 91.0
TLS3_k127_7353700_0 Belongs to the galactose-1-phosphate uridylyltransferase type 1 family K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 411.0
TLS3_k127_7353700_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000363 225.0
TLS3_k127_7353700_2 Bacterial regulatory proteins, deoR family - - - 0.00000000000000237 78.0
TLS3_k127_7358164_0 4Fe-4S dicluster domain - - - 1.088e-272 868.0
TLS3_k127_7358164_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 347.0
TLS3_k127_7358164_2 PFAM Myo-inositol catabolism IolB domain protein K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 346.0
TLS3_k127_7358164_3 Peptidase M14, carboxypeptidase A K05996 - 3.4.17.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004 297.0
TLS3_k127_7358164_4 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 301.0
TLS3_k127_7358164_5 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.00000000000000000000000000000048 132.0
TLS3_k127_7358164_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000002626 75.0
TLS3_k127_7358164_7 PIN domain K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.000003165 57.0
TLS3_k127_7364037_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000006923 142.0
TLS3_k127_7364037_1 DNA polymerase Ligase (LigD) K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000002067 55.0
TLS3_k127_737069_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 6.213e-255 792.0
TLS3_k127_737069_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.299e-199 637.0
TLS3_k127_737069_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 480.0
TLS3_k127_737069_3 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 447.0
TLS3_k127_737069_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 385.0
TLS3_k127_737069_5 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 359.0
TLS3_k127_737069_6 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002426 261.0
TLS3_k127_737069_7 Periplasmic binding protein LacI transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000428 198.0
TLS3_k127_737069_8 Major facilitator superfamily - - - 0.0001081 48.0
TLS3_k127_7395474_0 ABC transporter K06147 - - 3.32e-224 711.0
TLS3_k127_7395474_1 ABC transporter transmembrane region K06147 - - 4.309e-203 647.0
TLS3_k127_7395474_2 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000005571 138.0
TLS3_k127_7395474_3 SpoIID LytB domain protein K06381 - - 0.00000000000000009393 94.0
TLS3_k127_7395474_4 Transglycosylase associated protein - - - 0.000000000000001939 79.0
TLS3_k127_7395474_5 transcriptional - - - 0.000000005812 63.0
TLS3_k127_7409231_0 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 457.0
TLS3_k127_7409231_1 ABC transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 428.0
TLS3_k127_7409231_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 379.0
TLS3_k127_7409231_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 321.0
TLS3_k127_7409231_4 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000004722 265.0
TLS3_k127_7409231_5 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000002914 97.0
TLS3_k127_74233_0 von Willebrand factor type A domain - - - 1.046e-225 766.0
TLS3_k127_74233_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 334.0
TLS3_k127_7449873_0 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 329.0
TLS3_k127_7449873_1 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000003549 236.0
TLS3_k127_7449873_2 Putative serine dehydratase domain K19967 - 4.1.2.42 0.000000000000000000000000000000000000000000000000000001623 211.0
TLS3_k127_7449873_3 amine dehydrogenase activity - - - 0.00000000000000002071 93.0
TLS3_k127_7480156_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001601 269.0
TLS3_k127_7480156_1 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000003934 206.0
TLS3_k127_7480156_2 Hep Hag repeat protein - - - 0.00000000000000000000147 98.0
TLS3_k127_750568_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1138.0
TLS3_k127_750568_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 566.0
TLS3_k127_750568_10 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000001155 156.0
TLS3_k127_750568_11 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000005893 151.0
TLS3_k127_750568_12 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000002127 147.0
TLS3_k127_750568_13 Cupin 2, conserved barrel domain protein K00450,K01628 - 1.13.11.4,4.1.2.17 0.000000000000000000000000000006066 133.0
TLS3_k127_750568_14 Peptidase, M20 - - - 0.0000000000000000000000005813 120.0
TLS3_k127_750568_15 PIN domain - - - 0.0000000000000000000009046 103.0
TLS3_k127_750568_16 Ribbon-helix-helix protein, copG family - - - 0.0000000001549 66.0
TLS3_k127_750568_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 472.0
TLS3_k127_750568_3 Aminotransferase class-V K00839 - 2.6.1.112 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 418.0
TLS3_k127_750568_4 aminopeptidase activity K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 416.0
TLS3_k127_750568_5 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 351.0
TLS3_k127_750568_6 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 322.0
TLS3_k127_750568_7 NAD dependent epimerase/dehydratase family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008172 279.0
TLS3_k127_750568_8 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000001111 236.0
TLS3_k127_750568_9 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000005404 184.0
TLS3_k127_7553642_0 Belongs to the FGGY kinase family K00864 - 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 458.0
TLS3_k127_7553642_1 myo-inosose-2 dehydratase activity K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 427.0
TLS3_k127_7553642_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 410.0
TLS3_k127_7553642_3 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 393.0
TLS3_k127_7553642_4 Putative sugar-binding domain - - - 0.0000000000000000000000000000000000000000000000000000001325 200.0
TLS3_k127_7556237_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 560.0
TLS3_k127_7556237_1 B12 binding domain K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 451.0
TLS3_k127_7556237_2 mandelate racemase muconate lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 447.0
TLS3_k127_7556237_3 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001878 293.0
TLS3_k127_7556237_4 Glutamine cyclotransferase K00683 - 2.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000003133 243.0
TLS3_k127_7556237_5 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000006857 230.0
TLS3_k127_7556237_6 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000006114 166.0
TLS3_k127_7556237_7 META domain - - - 0.000000000000000001529 100.0
TLS3_k127_7556237_8 META domain - - - 0.0000000411 66.0
TLS3_k127_7556237_9 Major facilitator Superfamily K08223 - - 0.00001821 53.0
TLS3_k127_7589562_0 acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000005173 104.0
TLS3_k127_7629920_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 580.0
TLS3_k127_7629920_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000001485 158.0
TLS3_k127_7629920_2 Methylpurine-DNA glycosylase (MPG) K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000007738 57.0
TLS3_k127_7656438_0 PFAM NADH Ubiquinone plastoquinone (complex I) K14086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 454.0
TLS3_k127_7656438_1 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.0000000000000000000003295 102.0
TLS3_k127_7682102_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000001558 215.0
TLS3_k127_7682102_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000003658 194.0
TLS3_k127_7682102_2 cellulose binding - - - 0.00000000000000000008137 106.0
TLS3_k127_7708112_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 475.0
TLS3_k127_7708112_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000006291 191.0
TLS3_k127_7708112_2 Sap, sulfolipid-1-addressing protein - - - 0.0000000000000000000000000000000000000000003942 166.0
TLS3_k127_7708112_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000003639 139.0
TLS3_k127_7708112_4 Protein of unknown function (DUF952) - - - 0.00000000000000000000000465 108.0
TLS3_k127_7708112_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000001102 58.0
TLS3_k127_7782506_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.804e-213 687.0
TLS3_k127_7782506_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 502.0
TLS3_k127_7782506_10 Glucose dehydrogenase C-terminus - - - 0.000000000349 65.0
TLS3_k127_7782506_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.0002904 54.0
TLS3_k127_7782506_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 396.0
TLS3_k127_7782506_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006363 290.0
TLS3_k127_7782506_4 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000005771 246.0
TLS3_k127_7782506_5 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000002961 241.0
TLS3_k127_7782506_6 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000001888 196.0
TLS3_k127_7782506_7 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000001848 168.0
TLS3_k127_7782506_8 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000002129 121.0
TLS3_k127_7782506_9 - - - - 0.000000000000000000000003018 111.0
TLS3_k127_7791939_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004684 263.0
TLS3_k127_7791939_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000003547 167.0
TLS3_k127_7791939_2 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000004121 151.0
TLS3_k127_7797700_1 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000001251 122.0
TLS3_k127_7797700_2 Sigma-70 region 2 K03088 - - 0.000000000000000000002062 106.0
TLS3_k127_7810975_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000005288 232.0
TLS3_k127_7810975_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000002635 180.0
TLS3_k127_7815542_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000001785 229.0
TLS3_k127_7815542_1 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000000000000000000000382 201.0
TLS3_k127_7815542_2 TrkA-N domain K03499,K10716 - - 0.00000000000000000000000000004574 126.0
TLS3_k127_7815542_3 Universal stress protein family - - - 0.0000000000000000000007944 104.0
TLS3_k127_7815542_4 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000002987 94.0
TLS3_k127_7815542_5 Metal-sensitive transcriptional repressor K21600 - - 0.0001485 45.0
TLS3_k127_7818243_0 PFAM permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 340.0
TLS3_k127_7818243_1 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 325.0
TLS3_k127_7818243_10 arsR family transcriptional regulator K03892 - - 0.00000001169 62.0
TLS3_k127_7818243_11 Belongs to the MIP aquaporin (TC 1.A.8) family K09874 GO:0003674,GO:0005215,GO:0005372,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006833,GO:0008150,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042044,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000002359 59.0
TLS3_k127_7818243_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000266 167.0
TLS3_k127_7818243_3 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.000000000000000000004057 104.0
TLS3_k127_7818243_4 TIGRFAM redox-active disulfide protein 2 - - - 0.000000000000000001306 92.0
TLS3_k127_7818243_5 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000008685 85.0
TLS3_k127_7818243_6 Low molecular weight phosphotyrosine protein phosphatase K03892 - - 0.00000000000000145 89.0
TLS3_k127_7818243_8 - - - - 0.000000003764 70.0
TLS3_k127_7818243_9 serine-type aminopeptidase activity K02030,K14475 - - 0.00000001066 66.0
TLS3_k127_7833506_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 321.0
TLS3_k127_7833506_1 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 303.0
TLS3_k127_7833506_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005635 232.0
TLS3_k127_7833506_3 - - - - 0.00000000000000000000000000284 116.0
TLS3_k127_78379_0 Branched-chain amino acid transport system / permease component K10440,K10441 - 3.6.3.17 1.459e-227 726.0
TLS3_k127_78379_1 Metallopeptidase family M24 - - - 4.698e-195 619.0
TLS3_k127_78379_10 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00001441 56.0
TLS3_k127_78379_2 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 482.0
TLS3_k127_78379_3 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 323.0
TLS3_k127_78379_4 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006277 274.0
TLS3_k127_78379_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002436 271.0
TLS3_k127_78379_6 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003677 278.0
TLS3_k127_78379_7 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000003188 223.0
TLS3_k127_78379_8 Alpha amylase, catalytic domain - - - 0.000000000001457 78.0
TLS3_k127_78379_9 Alpha amylase, catalytic domain - - - 0.00000000009201 72.0
TLS3_k127_7853990_0 Type II/IV secretion system protein K02283 - - 7.24e-203 640.0
TLS3_k127_7853990_1 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 338.0
TLS3_k127_7853990_2 PFAM type II secretion system protein K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000004603 243.0
TLS3_k127_7853990_3 SAF K02279 - - 0.00000000000001322 83.0
TLS3_k127_7867773_0 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 507.0
TLS3_k127_7867773_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000001141 192.0
TLS3_k127_7867773_2 Mannosyltransferase (PIG-V) - - - 0.0000000000000000000000000000000000000001141 167.0
TLS3_k127_7867773_3 Peptidase, M23 - - - 0.00000000000000005255 93.0
TLS3_k127_7867773_4 cyclic nucleotide-binding - - - 0.000000004753 60.0
TLS3_k127_7871820_0 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.0000000000000000000000000000000000000000000000000000000000000000324 231.0
TLS3_k127_7871820_1 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000005885 170.0
TLS3_k127_7871820_2 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000003362 89.0
TLS3_k127_7882832_0 AAA domain - - - 1.64e-285 917.0
TLS3_k127_7882832_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 477.0
TLS3_k127_7882832_10 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000000000000000000000000000006092 140.0
TLS3_k127_7882832_12 InterPro IPR007367 - - - 0.00000000003561 72.0
TLS3_k127_7882832_13 Lysin motif - - - 0.00000004244 66.0
TLS3_k127_7882832_2 Ribosomal protein S4/S9 N-terminal domain K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000001561 241.0
TLS3_k127_7882832_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000414 233.0
TLS3_k127_7882832_4 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000001737 225.0
TLS3_k127_7882832_5 regulation of methylation-dependent chromatin silencing - - - 0.0000000000000000000000000000000000000000000000000001794 196.0
TLS3_k127_7882832_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000001596 162.0
TLS3_k127_7882832_7 Pfam:DUF2029 - - - 0.0000000000000000000000000000000000000003565 160.0
TLS3_k127_7882832_8 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000005906 162.0
TLS3_k127_7882832_9 Pfam:DUF2029 - - - 0.00000000000000000000000000000000000727 149.0
TLS3_k127_7906705_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 308.0
TLS3_k127_7906705_1 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000000000000009506 226.0
TLS3_k127_7906705_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000005414 117.0
TLS3_k127_7933455_0 Amidohydrolase K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 370.0
TLS3_k127_7933455_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 317.0
TLS3_k127_7933455_2 KR domain K08261,K21620 - 1.1.1.16,1.1.99.21 0.0000000000000000000000000225 121.0
TLS3_k127_7933455_3 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000006967 117.0
TLS3_k127_7933455_4 KR domain K00059 - 1.1.1.100 0.00000000000001234 83.0
TLS3_k127_7934250_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 329.0
TLS3_k127_7934250_1 Tyrosine recombinase XerD K04763 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001386 269.0
TLS3_k127_7934250_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000004098 160.0
TLS3_k127_7934250_3 Bacterial PH domain - - - 0.00009791 50.0
TLS3_k127_7942847_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000003273 151.0
TLS3_k127_7942847_1 Type II restriction enzyme K01155 - 3.1.21.4 0.000009473 58.0
TLS3_k127_7967387_0 Belongs to the DapA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 416.0
TLS3_k127_7967387_1 Extradiol ring-cleavage dioxygenase K15777 - - 0.0000000000000000000000000001202 117.0
TLS3_k127_7967387_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000001076 83.0
TLS3_k127_8010501_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 624.0
TLS3_k127_8010501_1 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 449.0
TLS3_k127_8010501_2 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 364.0
TLS3_k127_8010501_3 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 359.0
TLS3_k127_8010501_4 Bacterial extracellular solute-binding protein K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 354.0
TLS3_k127_8010501_5 Binding-protein-dependent transport system inner membrane component K02026,K10119,K17243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 340.0
TLS3_k127_8010501_6 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 300.0
TLS3_k127_8010501_7 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.000000000000000000000000000000000000000000000000000000003125 202.0
TLS3_k127_8010501_8 Belongs to the glycosyl hydrolase 3 family K01207,K05349 - 3.2.1.21,3.2.1.52 0.00000000000000000000000000000000000000001064 170.0
TLS3_k127_8015696_0 PFAM ABC transporter related K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 424.0
TLS3_k127_8015696_1 ABC transporter substrate-binding protein PnrA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 311.0
TLS3_k127_8015696_2 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009963 254.0
TLS3_k127_8015696_3 regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000006987 207.0
TLS3_k127_8025605_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 612.0
TLS3_k127_8025605_1 adenylyltransferase, small subunit K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 402.0
TLS3_k127_8026894_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 1.33e-265 827.0
TLS3_k127_8026894_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 335.0
TLS3_k127_8026894_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 306.0
TLS3_k127_8026894_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009548 244.0
TLS3_k127_8026894_4 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000006683 149.0
TLS3_k127_8026894_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000003732 120.0
TLS3_k127_8049011_0 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 315.0
TLS3_k127_8049011_1 helix_turn _helix lactose operon repressor K02525,K02529 - - 0.0000000000000000000000000000000000000000000004179 183.0
TLS3_k127_8064610_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 361.0
TLS3_k127_8064610_1 glycoside hydrolase, family K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000006959 190.0
TLS3_k127_8064610_2 - - - - 0.00000000006796 73.0
TLS3_k127_8064610_3 - - - - 0.0004348 51.0
TLS3_k127_8064806_0 - - - - 0.0000000000000000000000000000000000000000000000000000385 198.0
TLS3_k127_8066645_0 PFAM Helicase conserved C-terminal domain K06877 - - 5.036e-253 802.0
TLS3_k127_8066645_1 pathogenesis - - - 0.00000002758 63.0
TLS3_k127_8073716_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 482.0
TLS3_k127_8073716_1 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 484.0
TLS3_k127_8073716_10 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000001913 239.0
TLS3_k127_8073716_11 Class II Aldolase and Adducin N-terminal domain K08967 - 1.13.11.53,1.13.11.54 0.00000000000000000000000000000000001443 153.0
TLS3_k127_8073716_12 Putative tRNA binding domain K06878 - - 0.000000000000000000000000003954 119.0
TLS3_k127_8073716_13 Membrane protein insertase, YidC Oxa1 family K03217 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000001846 118.0
TLS3_k127_8073716_14 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000002555 95.0
TLS3_k127_8073716_15 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000675 72.0
TLS3_k127_8073716_16 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000001083 66.0
TLS3_k127_8073716_17 ARD/ARD' family - - - 0.00003593 53.0
TLS3_k127_8073716_18 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K12132 - 2.7.11.1,3.1.3.16 0.0002682 51.0
TLS3_k127_8073716_19 single-stranded nucleic acid binding R3H K06346 - - 0.0004059 52.0
TLS3_k127_8073716_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 364.0
TLS3_k127_8073716_3 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate K00899 - 2.7.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 349.0
TLS3_k127_8073716_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 332.0
TLS3_k127_8073716_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001225 287.0
TLS3_k127_8073716_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001407 278.0
TLS3_k127_8073716_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001794 276.0
TLS3_k127_8073716_8 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003462 269.0
TLS3_k127_8073716_9 ABC-type transport system, periplasmic component surface lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000008822 249.0
TLS3_k127_8074042_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 3.019e-216 685.0
TLS3_k127_8074042_1 PFAM MMPL domain protein K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008668 583.0
TLS3_k127_8074042_2 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003254 287.0
TLS3_k127_8074042_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000001646 208.0
TLS3_k127_8074042_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000234 147.0
TLS3_k127_8074042_5 OsmC-like protein K07397 - - 0.0000000000000002771 86.0
TLS3_k127_8074042_6 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.00000000000002162 78.0
TLS3_k127_8079589_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 569.0
TLS3_k127_8079589_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 493.0
TLS3_k127_8079589_2 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 452.0
TLS3_k127_8082695_0 beta-N-acetylglucosaminidase K01197 - 3.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 533.0
TLS3_k127_8082695_1 protein containing SIS (Sugar isomerase) phosphosugar binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001 266.0
TLS3_k127_8082695_2 N-acetylglucosamine kinase activity K18676 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047931 2.7.1.8 0.0000004895 55.0
TLS3_k127_8084624_0 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 295.0
TLS3_k127_8084624_1 Acetyltransferase (GNAT) domain K22441 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464,GO:0048583,GO:0050789,GO:0065007,GO:0080134,GO:1902882 2.3.1.57 0.000000000000000000000000000000000000000000000000002617 194.0
TLS3_k127_8084624_2 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000002261 158.0
TLS3_k127_8084624_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000006874 142.0
TLS3_k127_8084624_4 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000002114 126.0
TLS3_k127_8084624_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000226 130.0
TLS3_k127_8084624_6 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000001704 132.0
TLS3_k127_8084624_7 Glycosyltransferase like family 2 - - - 0.0000000001049 66.0
TLS3_k127_8105493_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000003392 252.0
TLS3_k127_8105493_1 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006548 223.0
TLS3_k127_8105493_2 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000007298 179.0
TLS3_k127_8119446_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 416.0
TLS3_k127_8119446_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000001357 235.0
TLS3_k127_8119446_2 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000004742 209.0
TLS3_k127_8119446_3 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000004536 177.0
TLS3_k127_8119446_4 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000285 160.0
TLS3_k127_8119446_5 - - - - 0.000001044 60.0
TLS3_k127_8132149_0 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 603.0
TLS3_k127_8132149_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002025 248.0
TLS3_k127_8132149_2 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000004762 224.0
TLS3_k127_8132149_3 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000003424 200.0
TLS3_k127_8132149_4 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000009444 81.0
TLS3_k127_8132149_5 transcriptional regulator - - - 0.000000000000002082 83.0
TLS3_k127_8132149_6 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000024 79.0
TLS3_k127_8134944_0 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 294.0
TLS3_k127_8134944_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000004075 131.0
TLS3_k127_8134944_2 protein conserved in bacteria K09796 - - 0.000000000000000000000001603 110.0
TLS3_k127_8134944_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000001647 94.0
TLS3_k127_8180490_0 5'-nucleotidase, C-terminal domain K01081,K01119 - 3.1.3.5,3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001409 305.0
TLS3_k127_8180490_1 DNA helicase K03656,K03657 - 3.6.4.12 0.00000000000000000000000000000000000000001139 169.0
TLS3_k127_8180490_2 YbhB YbcL family protein K06910 - - 0.000000000000000000000000000000000002841 159.0
TLS3_k127_8180490_3 - - - - 0.000000003161 70.0
TLS3_k127_821453_0 Zn-dependent metallo-hydrolase RNA specificity domain K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000007378 269.0
TLS3_k127_821453_1 bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000005219 113.0
TLS3_k127_821453_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 0.0000001915 63.0
TLS3_k127_8216881_0 xanthine dehydrogenase activity - - - 1.709e-200 657.0
TLS3_k127_8216881_1 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 472.0
TLS3_k127_8216881_2 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000005515 194.0
TLS3_k127_8216881_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000001668 143.0
TLS3_k127_8216881_4 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein - - - 0.00000000000000000000000008619 110.0
TLS3_k127_8225316_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000001632 169.0
TLS3_k127_8225316_1 AAA domain K01090 - 3.1.3.16 0.000000000000000000000000000000001197 139.0
TLS3_k127_8225316_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000003111 94.0
TLS3_k127_8225316_3 Haloacid dehalogenase-like hydrolase K19270 - 3.1.3.23 0.000000001116 67.0
TLS3_k127_8236008_0 Dihydropyrimidinase K01464 - 3.5.2.2 5.289e-194 618.0
TLS3_k127_8236008_1 PFAM transcriptional regulator domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 392.0
TLS3_k127_8236008_2 - - - - 0.000000000000000000000141 106.0
TLS3_k127_8239114_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003528 285.0
TLS3_k127_8239114_1 Belongs to the carbohydrate kinase PfkB family K18478 - 2.7.1.184 0.0000000000000000000000000000000000000003112 164.0
TLS3_k127_8242164_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 609.0
TLS3_k127_8242164_1 TIGRFAM drug resistance transporter, Bcr CflA subfamily K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 375.0
TLS3_k127_8242164_2 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000003986 141.0
TLS3_k127_8242164_3 acetyltransferase K06975 - - 0.00000000000000000000000001721 112.0
TLS3_k127_8242164_4 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.000000000005083 77.0
TLS3_k127_8242164_5 recA bacterial DNA recombination protein - - - 0.0000000002485 72.0
TLS3_k127_8242164_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 - 2.7.7.7 0.000000001565 68.0
TLS3_k127_8242164_7 Domain of unknown function (DUF1905) - - - 0.0001071 44.0
TLS3_k127_8259745_0 elongation factor G K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 606.0
TLS3_k127_8259745_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 361.0
TLS3_k127_8259745_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000245 280.0
TLS3_k127_8259745_3 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001869 261.0
TLS3_k127_8259745_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000646 185.0
TLS3_k127_8259745_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000402 184.0
TLS3_k127_8259745_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000003545 147.0
TLS3_k127_8259745_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000007404 136.0
TLS3_k127_8259745_8 TIGRFAM TrpR like protein, YerC YecD - - - 0.000000000000000003064 88.0
TLS3_k127_8303763_0 ERAP1-like C-terminal domain K01256,K08776 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 623.0
TLS3_k127_8303763_1 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 500.0
TLS3_k127_8303763_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000409 133.0
TLS3_k127_8304680_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 366.0
TLS3_k127_8304680_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 344.0
TLS3_k127_8304680_2 laci family transcriptional regulator K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005262 272.0
TLS3_k127_8304680_3 (ABC) transporter K10554 - - 0.00000000000000000000000000000000000000000000000000000000000000000004332 241.0
TLS3_k127_8304680_4 PFAM Inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000008411 226.0
TLS3_k127_8304680_5 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000004042 204.0
TLS3_k127_8304680_6 Enoyl-(Acyl carrier protein) reductase K18009 - 1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000003848 187.0
TLS3_k127_8304680_7 UTRA K03710 - - 0.0000000000000000000000000000000000001803 151.0
TLS3_k127_8304680_8 pfkB family carbohydrate kinase K00882 - 2.7.1.56 0.000000000000000000000000000005892 132.0
TLS3_k127_830951_0 COGs COG3367 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 300.0
TLS3_k127_830951_1 Predicted membrane protein (DUF2207) - - - 0.0000000001009 74.0
TLS3_k127_8333012_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000004427 237.0
TLS3_k127_8344544_0 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000004738 160.0
TLS3_k127_8344544_1 Endoribonuclease L-PSP - - - 0.0000000000000000000001853 102.0
TLS3_k127_8344544_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000001401 82.0
TLS3_k127_8345802_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 361.0
TLS3_k127_8345802_1 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000009097 233.0
TLS3_k127_8345802_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000006671 192.0
TLS3_k127_8345802_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000002658 127.0
TLS3_k127_8345802_4 rRNA binding K02909 - - 0.00000000000000000000003328 103.0
TLS3_k127_8345802_5 N-terminal domain of (some) glycogen debranching enzymes - - - 0.000000000000000000002339 105.0
TLS3_k127_8345802_6 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000006341 98.0
TLS3_k127_8345802_7 heat shock protein binding - - - 0.0000000000009271 72.0
TLS3_k127_8356892_0 Phosphatidylinositol - - - 0.000000000000000000000000000000000000000000000000000000000000000000003259 245.0
TLS3_k127_8356892_1 ketosteroid isomerase - - - 0.00000000000000000000000000000000000000000000003786 177.0
TLS3_k127_8356892_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000001201 166.0
TLS3_k127_8356892_3 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000004238 173.0
TLS3_k127_8356892_4 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000005363 100.0
TLS3_k127_8356892_5 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000001341 66.0
TLS3_k127_838680_0 Amidohydrolase family K01464,K01466 - 3.5.2.2,3.5.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 310.0
TLS3_k127_838680_1 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin K00365 - 1.7.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 301.0
TLS3_k127_838680_2 Protein of unknown function (DUF3830) - - - 0.00000000000000000000000000000000000000000000008597 173.0
TLS3_k127_838680_3 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.00000000000000000000000000003375 122.0
TLS3_k127_838680_4 OHCU decarboxylase - - - 0.000000000000000000001289 103.0
TLS3_k127_838680_5 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.00000000000000000001761 95.0
TLS3_k127_838680_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000008022 64.0
TLS3_k127_8401194_0 Integral membrane protein TerC family K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 340.0
TLS3_k127_8401194_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 317.0
TLS3_k127_8401194_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000504 276.0
TLS3_k127_8401194_3 Regulator of polyketide synthase expression - GO:0008150,GO:0040007 - 0.000005329 58.0
TLS3_k127_8401348_0 SMP-30/Gluconolaconase/LRE-like region K01053,K02352 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000008168 259.0
TLS3_k127_8401348_1 permease - - - 0.00000000000000000000000000000000000000000000000000000000003364 217.0
TLS3_k127_8401348_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000006632 192.0
TLS3_k127_8401348_3 Bacterial extracellular solute-binding protein K02027 - - 0.000000002164 67.0
TLS3_k127_8409632_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 538.0
TLS3_k127_8409632_1 Thiamine pyrophosphate enzyme, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 454.0
TLS3_k127_8409632_10 amino acid ABC transporter K02029 - - 0.000000000000000000000000000000001529 138.0
TLS3_k127_8409632_11 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000000000000000000072 131.0
TLS3_k127_8409632_12 acid ABC transporter K02029,K02424,K10009 - - 0.000000000000000000000000000335 122.0
TLS3_k127_8409632_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000003003 116.0
TLS3_k127_8409632_14 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000001856 111.0
TLS3_k127_8409632_15 Domain of unknown function (DUF1905) - - - 0.00001613 51.0
TLS3_k127_8409632_2 PFAM alanine dehydrogenase PNT domain protein K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 432.0
TLS3_k127_8409632_3 ABC transporter, ATP-binding protein K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 302.0
TLS3_k127_8409632_4 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000409 282.0
TLS3_k127_8409632_5 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006704 254.0
TLS3_k127_8409632_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001645 196.0
TLS3_k127_8409632_7 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000002436 183.0
TLS3_k127_8409632_8 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000005598 157.0
TLS3_k127_8409632_9 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000001629 143.0
TLS3_k127_8410076_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 304.0
TLS3_k127_8410076_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 298.0
TLS3_k127_8410076_2 Imidazoleglycerol-phosphate dehydratase K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000002435 217.0
TLS3_k127_8410076_3 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000005049 181.0
TLS3_k127_8410076_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000003716 179.0
TLS3_k127_8410076_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 0.000000003226 62.0
TLS3_k127_8433309_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.109e-267 844.0
TLS3_k127_8433309_1 CAAX protease self-immunity K07052 - - 0.0003227 52.0
TLS3_k127_8449196_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 447.0
TLS3_k127_8449196_1 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 332.0
TLS3_k127_8449196_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K00982,K03564 - 1.11.1.15,2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000004735 197.0
TLS3_k127_8449196_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000325 198.0
TLS3_k127_8449196_4 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000006365 189.0
TLS3_k127_8449196_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000001742 173.0
TLS3_k127_8516593_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K05587 - 1.6.5.3 7.92e-207 657.0
TLS3_k127_8516593_1 Luciferase-like monooxygenase - - - 5.673e-202 635.0
TLS3_k127_8516593_10 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000000000000000000000000203 199.0
TLS3_k127_8516593_11 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000005219 208.0
TLS3_k127_8516593_12 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K05586 - 1.6.5.3 0.00000000000000000000000000000000000000000000000003202 196.0
TLS3_k127_8516593_13 dihydrodipicolinate reductase - - - 0.000000000000000000000000000000000000000000000002127 188.0
TLS3_k127_8516593_14 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000004029 178.0
TLS3_k127_8516593_15 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000003844 129.0
TLS3_k127_8516593_16 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000001316 129.0
TLS3_k127_8516593_17 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000001197 119.0
TLS3_k127_8516593_18 Ribosomal L25p family K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000124 123.0
TLS3_k127_8516593_19 - - - - 0.000000000000000000000007007 105.0
TLS3_k127_8516593_2 PFAM nickel-dependent hydrogenase, large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 3.013e-194 619.0
TLS3_k127_8516593_20 PFAM nitroreductase - GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000008705 117.0
TLS3_k127_8516593_21 TIGRFAM hydrogenase maturation protease - - - 0.0000000000000004987 92.0
TLS3_k127_8516593_22 protein with SCP PR1 domains - - - 0.00000000000004013 82.0
TLS3_k127_8516593_23 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000002542 77.0
TLS3_k127_8516593_24 PFAM heat shock protein DnaJ domain protein K05516 - - 0.00000000009106 72.0
TLS3_k127_8516593_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 336.0
TLS3_k127_8516593_4 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K05299,K05588 - 1.17.1.10,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 312.0
TLS3_k127_8516593_5 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 305.0
TLS3_k127_8516593_6 coenzyme F420 hydrogenase activity K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000329 226.0
TLS3_k127_8516593_7 NADPH-dependent FMN reductase K00299 - 1.5.1.38 0.000000000000000000000000000000000000000000000000000000000000001714 231.0
TLS3_k127_8516593_8 response regulator receiver K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000001035 225.0
TLS3_k127_8516593_9 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000001913 235.0
TLS3_k127_8549240_0 ABC transporter K10562 - 3.6.3.17 4.948e-208 664.0
TLS3_k127_8549240_1 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 381.0
TLS3_k127_8549240_2 Belongs to the binding-protein-dependent transport system permease family K10561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 371.0
TLS3_k127_8549240_3 GMC oxidoreductase K00108 - 1.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 317.0
TLS3_k127_8573153_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009768 581.0
TLS3_k127_8573153_1 Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 295.0
TLS3_k127_8573153_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000005026 271.0
TLS3_k127_8573153_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000002948 257.0
TLS3_k127_8573153_4 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000001734 89.0
TLS3_k127_8573153_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000103 78.0
TLS3_k127_8573153_6 PFAM blue (type 1) copper domain protein - - - 0.0000000004632 72.0
TLS3_k127_859607_0 peptidase S8 - - - 0.00000000000000000000000000000000000000000000000000000000000001306 244.0
TLS3_k127_859607_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000002106 188.0
TLS3_k127_863337_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000002792 260.0
TLS3_k127_863337_1 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000003227 162.0
TLS3_k127_869115_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 368.0
TLS3_k127_869115_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000006979 188.0
TLS3_k127_869115_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000007952 173.0
TLS3_k127_869115_3 Belongs to the glycosyl hydrolase 26 family - - - 0.00000000000000000000000000000000000003445 158.0
TLS3_k127_869115_4 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000003315 124.0
TLS3_k127_869115_5 Glycosyl hydrolase family 26 - - - 0.0000000000000000000000000001179 129.0
TLS3_k127_869115_6 Glycosyl transferases group 1 - - - 0.00001043 49.0
TLS3_k127_877532_0 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 291.0
TLS3_k127_877532_1 NUDIX domain - - - 0.00000000000000000000000000000000000000466 154.0
TLS3_k127_877532_2 Pfam Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000009282 157.0
TLS3_k127_877532_3 Glycosyltransferase Family 4 - - - 0.0000000000000000009495 100.0
TLS3_k127_877532_4 Glycosyl transferase 4-like domain - - - 0.00000000000000009172 94.0
TLS3_k127_893225_0 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 3.336e-194 624.0
TLS3_k127_893225_1 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 601.0
TLS3_k127_893225_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001385 305.0
TLS3_k127_893225_3 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000004256 196.0
TLS3_k127_893225_4 DNA mismatch endonuclease vsr K07458 - - 0.0000000000000000000000000000000000000002203 154.0
TLS3_k127_893225_5 Micrococcal nuclease (thermonuclease) homologs K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.0000000000000000000000000000000000113 149.0
TLS3_k127_893225_6 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000848 141.0
TLS3_k127_893225_7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000009852 112.0
TLS3_k127_893225_8 ABC transporter substrate-binding protein K10543 - - 0.000000000008531 78.0
TLS3_k127_893225_9 Copper binding proteins, plastocyanin/azurin family - - - 0.0000002485 59.0
TLS3_k127_922663_0 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 328.0
TLS3_k127_922663_1 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 298.0
TLS3_k127_922663_2 ABC-type sugar transport systems permease components K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 294.0
TLS3_k127_922663_3 isomerase - - - 0.00000002373 60.0
TLS3_k127_929854_0 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 452.0
TLS3_k127_929854_1 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 352.0
TLS3_k127_929854_2 Fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 338.0
TLS3_k127_961754_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001664 276.0
TLS3_k127_961754_1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.00000000000000000000000000000000001867 146.0
TLS3_k127_961754_2 Cytochrome c oxidase subunit III - - - 0.0000000625 63.0
TLS3_k127_961754_3 RecX family K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001104 57.0
TLS3_k127_964935_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.062e-217 683.0
TLS3_k127_964935_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.307e-211 668.0
TLS3_k127_964935_10 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000007787 126.0
TLS3_k127_964935_11 ATP synthase delta (OSCP) subunit K02113 - - 0.0000000000000000000000006005 111.0
TLS3_k127_964935_12 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000004109 94.0
TLS3_k127_964935_13 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.0000000000001503 75.0
TLS3_k127_964935_14 Helix-turn-helix domain - - - 0.0001077 50.0
TLS3_k127_964935_15 Glycosyltransferase family 87 - - - 0.0007048 51.0
TLS3_k127_964935_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 453.0
TLS3_k127_964935_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 344.0
TLS3_k127_964935_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000766 254.0
TLS3_k127_964935_5 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000000000000000001999 215.0
TLS3_k127_964935_6 PFAM type II secretion system K12511 - - 0.0000000000000000000000000000000000002366 143.0
TLS3_k127_964935_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000009785 143.0
TLS3_k127_964935_8 competence protein - - - 0.00000000000000000000000000000009795 132.0
TLS3_k127_964935_9 PHP-associated - - - 0.0000000000000000000000000000001303 134.0