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Overview

ID MAG04034
Name TLS3_bin.10
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Xanthomonadales
Family Xanthomonadaceae
Genus Lysobacter_I
Species
Assembly information
Completeness (%) 94.18
Contamination (%) 1.37
GC content (%) 66.0
N50 (bp) 18,393
Genome size (bp) 3,781,211

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3165

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1010569_0 ankyrin repeat K06867 - - 0.0 1298.0
TLS3_k127_1010569_1 peptidase - - - 0.0 1248.0
TLS3_k127_1010569_11 Tryptophan halogenase K14266 - 1.14.19.9 0.0000000000000000000000005224 105.0
TLS3_k127_1010569_2 phosphoribosyltransferase K03462 - 2.4.2.12 5.672e-277 878.0
TLS3_k127_1010569_3 oxidase, subunit K00425 - 1.10.3.14 1.36e-233 730.0
TLS3_k127_1010569_4 involved in creation of nicotanimide adenine dinucleotide NAD from either biosynthetic or salvage pathways K13522 - 2.7.7.1 2.753e-204 638.0
TLS3_k127_1010569_5 oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 557.0
TLS3_k127_1010569_6 membrane K03760 - 2.7.8.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 484.0
TLS3_k127_1010569_7 Ribonuclease - - - 0.0000000000000000000000000000000000000000000005413 166.0
TLS3_k127_1010569_8 YcgL domain-containing protein K09902 - - 0.0000000000000000000000000000000000000005067 149.0
TLS3_k127_1010569_9 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000009076 143.0
TLS3_k127_1025562_0 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 3.619e-239 742.0
TLS3_k127_1025562_1 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 387.0
TLS3_k127_1025562_2 UPF0114 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 302.0
TLS3_k127_1025562_3 peptidase K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000006844 215.0
TLS3_k127_1052045_0 Belongs to the Orn Lys Arg decarboxylase class-II family K12526 - 2.7.2.4,4.1.1.20 0.0 1037.0
TLS3_k127_1052045_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 6.229e-232 730.0
TLS3_k127_1052045_2 phenazine biosynthesis protein PhzF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 473.0
TLS3_k127_1052045_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 347.0
TLS3_k127_1052045_4 phenazine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 342.0
TLS3_k127_1052045_5 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 296.0
TLS3_k127_1052045_6 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000000000000006926 198.0
TLS3_k127_1052045_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000002285 175.0
TLS3_k127_1052045_8 - - - - 0.0001326 51.0
TLS3_k127_1053640_0 membrane protein terc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 382.0
TLS3_k127_1053640_1 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000000000002326 210.0
TLS3_k127_1053640_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07638 - 2.7.13.3 0.00000000000000000000000000000000000002637 150.0
TLS3_k127_1053640_3 LemA family K03744 - - 0.00000000000000000000000000284 114.0
TLS3_k127_1069085_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 425.0
TLS3_k127_1069085_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 422.0
TLS3_k127_1069085_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 355.0
TLS3_k127_1071171_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.433e-290 904.0
TLS3_k127_1071171_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 374.0
TLS3_k127_1071171_2 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 377.0
TLS3_k127_1071171_3 protein conserved in bacteria K09973 - - 0.00000000000000000000000000000000000000000000000000000000008219 225.0
TLS3_k127_1120634_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 630.0
TLS3_k127_1120634_1 acid dehydrogenase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 592.0
TLS3_k127_1120634_2 membrane K07148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 430.0
TLS3_k127_1120634_3 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 408.0
TLS3_k127_1120634_4 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000006871 267.0
TLS3_k127_1120634_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000279 265.0
TLS3_k127_1122908_0 regulates genes involved in forming a 2',3'-cyclic phosphodiester on RNA K14414 - - 2.799e-284 880.0
TLS3_k127_1122908_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.655e-239 747.0
TLS3_k127_1122908_2 protein containing a von Willebrand factor type A (vWA) domain K11089 - - 4.797e-237 743.0
TLS3_k127_1122908_3 Catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 441.0
TLS3_k127_1122908_4 regulator K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 356.0
TLS3_k127_1122908_6 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000006478 113.0
TLS3_k127_1146933_0 PKS_KR - - - 0.0 1782.0
TLS3_k127_1146933_1 Thioesterase domain - - - 1.873e-262 854.0
TLS3_k127_1146933_2 oxidoreductase activity K13612,K13613,K13614 - - 9.531e-252 828.0
TLS3_k127_1146933_3 Patched family K07003 - - 3.928e-250 791.0
TLS3_k127_1146933_4 Aminotransferase class-III - - - 4.736e-223 707.0
TLS3_k127_1146933_5 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 422.0
TLS3_k127_1146933_6 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005026 282.0
TLS3_k127_1146933_7 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000004497 218.0
TLS3_k127_1166706_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1320.0
TLS3_k127_1166706_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.824e-255 792.0
TLS3_k127_1166706_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 334.0
TLS3_k127_1166706_11 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 327.0
TLS3_k127_1166706_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001714 272.0
TLS3_k127_1166706_13 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000002261 222.0
TLS3_k127_1166706_14 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000001315 141.0
TLS3_k127_1166706_15 - - - - 0.00000003783 59.0
TLS3_k127_1166706_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 1.206e-202 634.0
TLS3_k127_1166706_3 peptidylprolyl isomerase K03770 - 5.2.1.8 1.496e-200 644.0
TLS3_k127_1166706_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 559.0
TLS3_k127_1166706_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 539.0
TLS3_k127_1166706_6 Catalyzes a key regulatory step in fatty acid biosynthesis K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 435.0
TLS3_k127_1166706_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 393.0
TLS3_k127_1166706_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 381.0
TLS3_k127_1166706_9 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 349.0
TLS3_k127_1189039_0 TonB-dependent receptor - - - 0.0 1402.0
TLS3_k127_1189039_1 Tryptophan halogenase - - - 3.353e-217 685.0
TLS3_k127_1189039_2 Tryptophan halogenase K14266 - 1.14.19.9 1.036e-216 698.0
TLS3_k127_1189039_3 transcriptional K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 499.0
TLS3_k127_1189039_4 Cupin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006759 469.0
TLS3_k127_1189039_5 SapC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003712 280.0
TLS3_k127_1189039_6 COG1472 Beta-glucosidase-related glycosidases K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000001128 228.0
TLS3_k127_1190188_0 ImcF-related N-terminal domain K11891 - - 1.552e-223 740.0
TLS3_k127_1190188_1 ImpA, N-terminal, type VI secretion system K11902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006237 285.0
TLS3_k127_1190188_2 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.000000000000000000000000000000000000000000000000000000000000001222 235.0
TLS3_k127_1190188_3 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000006149 176.0
TLS3_k127_1190188_4 Type VI secretion system protein DotU K11892 - - 0.0000000000000000000000000000000000000000000005801 178.0
TLS3_k127_1190188_5 - - - - 0.00000000000000000000000000000000000000181 150.0
TLS3_k127_1190188_6 Domain of unknown function (DUF2383) - - - 0.00000000000000000000000000000000003211 141.0
TLS3_k127_1190188_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000002757 95.0
TLS3_k127_1193890_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 603.0
TLS3_k127_1193890_1 pfam abc K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 363.0
TLS3_k127_1193890_2 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000001523 211.0
TLS3_k127_1210613_0 dehydrogenase K00382 - 1.8.1.4 7.888e-279 870.0
TLS3_k127_1210613_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.405e-201 636.0
TLS3_k127_1210613_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 417.0
TLS3_k127_1210613_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 321.0
TLS3_k127_1210613_4 Asp/Glu/Hydantoin racemase K01779 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 316.0
TLS3_k127_1210613_5 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002443 277.0
TLS3_k127_1210613_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000000000003146 239.0
TLS3_k127_1210613_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000006665 225.0
TLS3_k127_1210613_8 ATP synthase subunit C - - - 0.00000000000000000000000000000000000004253 145.0
TLS3_k127_1210613_9 Predicted membrane protein (DUF2061) - - - 0.000000000000005292 79.0
TLS3_k127_1214056_0 catalase activity - - - 8e-323 1019.0
TLS3_k127_1214056_1 Belongs to the aldehyde dehydrogenase family K00138 - - 1.372e-300 926.0
TLS3_k127_1214056_10 - - - - 0.0000225 54.0
TLS3_k127_1214056_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.442e-300 926.0
TLS3_k127_1214056_3 Bacterial regulatory protein, Fis family K21405 - - 5.736e-262 823.0
TLS3_k127_1214056_4 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 305.0
TLS3_k127_1214056_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002162 258.0
TLS3_k127_1214056_6 geranylgeranyl reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009254 256.0
TLS3_k127_1214056_7 Protein of unknown function (DUF779) K09959 - - 0.0000000000000000000000000000000000000000000000000000000000000003278 222.0
TLS3_k127_1214056_8 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000000000000000000005946 189.0
TLS3_k127_1214056_9 - - - - 0.000001474 57.0
TLS3_k127_121475_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1214.0
TLS3_k127_121475_1 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 1.624e-271 839.0
TLS3_k127_121475_2 coagulation factor 5 8 type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 578.0
TLS3_k127_121475_3 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 508.0
TLS3_k127_1223416_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1430.0
TLS3_k127_1223416_1 TonB dependent receptor K02014 - - 0.0 1210.0
TLS3_k127_1223416_10 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000000000000000000000006813 177.0
TLS3_k127_1223416_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000007092 172.0
TLS3_k127_1223416_12 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000000000000000001699 112.0
TLS3_k127_1223416_13 - - - - 0.0000000000000000000002545 112.0
TLS3_k127_1223416_14 Multidrug resistance efflux pump K03543 - - 0.00000000002364 76.0
TLS3_k127_1223416_16 - - - - 0.00006204 50.0
TLS3_k127_1223416_2 ABC transporter K06147 - - 3.401e-272 848.0
TLS3_k127_1223416_3 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 1.68e-225 716.0
TLS3_k127_1223416_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 606.0
TLS3_k127_1223416_5 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 545.0
TLS3_k127_1223416_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001382 269.0
TLS3_k127_1223416_7 Uncharacterized protein family UPF0029 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 259.0
TLS3_k127_1223416_8 Belongs to the UPF0354 family - - - 0.00000000000000000000000000000000000000000000000000000000001149 217.0
TLS3_k127_1223416_9 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000000000000000001389 204.0
TLS3_k127_1240193_0 COG2202 FOG PAS PAC domain K21025 - - 4.112e-290 906.0
TLS3_k127_1240193_1 lysine 2,3-aminomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 530.0
TLS3_k127_1240193_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 464.0
TLS3_k127_1240193_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 444.0
TLS3_k127_1240193_4 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 428.0
TLS3_k127_1240193_5 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 402.0
TLS3_k127_1240193_6 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 368.0
TLS3_k127_124244_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1617.0
TLS3_k127_124244_1 - - - - 0.00000000000000000000000000000168 128.0
TLS3_k127_124244_2 Protein of unknown function (DUF3047) - - - 0.00000000000391 67.0
TLS3_k127_1248350_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 394.0
TLS3_k127_1248350_1 of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000281 275.0
TLS3_k127_1248350_2 Protein of unknown function (DUF1244) K09948 - - 0.00000000000000000000000000000000000000000248 158.0
TLS3_k127_1372799_0 Phosphate starvation protein PhoH K07175 - - 6.584e-273 842.0
TLS3_k127_1372799_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 546.0
TLS3_k127_1372799_10 Gram-negative-bacterium-type cell outer membrane assembly - - - 0.00000000000000000000000000000000002956 146.0
TLS3_k127_1372799_11 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000005554 101.0
TLS3_k127_1372799_12 Bacteriophage CI repressor helix-turn-helix domain - - - 0.000000000000000000451 92.0
TLS3_k127_1372799_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 523.0
TLS3_k127_1372799_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 412.0
TLS3_k127_1372799_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 371.0
TLS3_k127_1372799_5 Glycine cleavage system regulatory protein K03567 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 350.0
TLS3_k127_1372799_6 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 354.0
TLS3_k127_1372799_7 Peroxiredoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000008515 263.0
TLS3_k127_1372799_8 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000002273 169.0
TLS3_k127_1372799_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000004232 168.0
TLS3_k127_1377872_0 ABC-type sulfate transport system, periplasmic component K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 486.0
TLS3_k127_1377872_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 473.0
TLS3_k127_1377872_2 Part of the ABC transporter complex cysAWTP involved in sulfate thiosulfate import K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 440.0
TLS3_k127_1377872_3 ABC-type sulfate transport system permease component K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 417.0
TLS3_k127_1377872_4 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 328.0
TLS3_k127_1388900_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.0 1039.0
TLS3_k127_1388900_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 8.084e-293 922.0
TLS3_k127_1388900_10 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001311 283.0
TLS3_k127_1388900_11 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005012 273.0
TLS3_k127_1388900_12 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001172 268.0
TLS3_k127_1388900_13 acetyltransferase K22441 - 2.3.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000008507 261.0
TLS3_k127_1388900_14 TonB C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002726 265.0
TLS3_k127_1388900_15 redox protein, regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001365 248.0
TLS3_k127_1388900_16 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005344 251.0
TLS3_k127_1388900_17 Acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000005909 205.0
TLS3_k127_1388900_18 Biopolymer transport protein K03560 - - 0.00000000000000000000000000000000000000000001576 166.0
TLS3_k127_1388900_19 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0006524 42.0
TLS3_k127_1388900_2 Involved in the TonB-independent uptake of proteins K03641 - - 1.93e-210 680.0
TLS3_k127_1388900_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 592.0
TLS3_k127_1388900_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 528.0
TLS3_k127_1388900_5 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 512.0
TLS3_k127_1388900_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 406.0
TLS3_k127_1388900_7 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 414.0
TLS3_k127_1388900_8 TolQ protein K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 361.0
TLS3_k127_1388900_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 326.0
TLS3_k127_13928_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1255.0
TLS3_k127_13928_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 406.0
TLS3_k127_13928_10 Protein of unknown function (DUF3106) - - - 0.00000000000000000000000000001659 124.0
TLS3_k127_13928_11 - - - - 0.00000000000000000007234 102.0
TLS3_k127_13928_12 - - - - 0.0000497 55.0
TLS3_k127_13928_2 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 369.0
TLS3_k127_13928_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 338.0
TLS3_k127_13928_4 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 291.0
TLS3_k127_13928_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002188 246.0
TLS3_k127_13928_6 - - - - 0.0000000000000000000000000000000000000000000000001881 204.0
TLS3_k127_13928_7 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000004329 183.0
TLS3_k127_13928_8 - - - - 0.00000000000000000000000000000000000000000000002969 178.0
TLS3_k127_13928_9 - - - - 0.00000000000000000000000000000000004026 145.0
TLS3_k127_1430534_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 3.881e-209 659.0
TLS3_k127_1430534_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 468.0
TLS3_k127_1430534_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 450.0
TLS3_k127_1430534_3 peptidase K07260 - 3.4.17.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 367.0
TLS3_k127_1430534_4 - - - - 0.00000000000000000000000000000000000000006118 154.0
TLS3_k127_1430534_5 - - - - 0.0000000000000000000001802 105.0
TLS3_k127_1430534_6 protein conserved in bacteria - - - 0.000000000000000000003332 94.0
TLS3_k127_1491125_0 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
TLS3_k127_1491125_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003454 266.0
TLS3_k127_1501629_0 TonB-dependent Receptor Plug Domain K02014 - - 0.0 1166.0
TLS3_k127_1501629_1 transporter - - - 1.908e-241 754.0
TLS3_k127_1501629_2 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 524.0
TLS3_k127_1501629_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 415.0
TLS3_k127_1507384_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 2.037e-280 873.0
TLS3_k127_1507384_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 3.712e-214 684.0
TLS3_k127_1507384_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000002592 146.0
TLS3_k127_1507384_11 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000000000108 124.0
TLS3_k127_1507384_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 2.872e-208 651.0
TLS3_k127_1507384_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 569.0
TLS3_k127_1507384_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 499.0
TLS3_k127_1507384_5 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 418.0
TLS3_k127_1507384_6 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005337 255.0
TLS3_k127_1507384_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000004028 221.0
TLS3_k127_1507384_8 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000003488 224.0
TLS3_k127_1585854_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 593.0
TLS3_k127_1585854_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 584.0
TLS3_k127_1585854_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 361.0
TLS3_k127_1596944_0 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 1.408e-253 796.0
TLS3_k127_1596944_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 556.0
TLS3_k127_1596944_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 349.0
TLS3_k127_1596944_3 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002753 256.0
TLS3_k127_1596944_4 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000000000641 212.0
TLS3_k127_1596944_5 - - - - 0.0000000000000000000000000000000000000000000007595 182.0
TLS3_k127_1596944_6 protein conserved in bacteria K09806 - - 0.000000000000000000000000000003079 122.0
TLS3_k127_160304_0 COG3321 Polyketide synthase modules and related proteins - - - 0.0 1895.0
TLS3_k127_160304_1 PKS_KR - - - 0.0 1748.0
TLS3_k127_160304_10 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005253 286.0
TLS3_k127_160304_11 protein, possibly involved in aromatic compounds catabolism K02614 - - 0.000000000000000000000000000000000000000000004535 171.0
TLS3_k127_160304_12 COG3321 Polyketide synthase modules and related proteins - - - 0.00000000000000000000000000000006983 134.0
TLS3_k127_160304_13 Phosphopantetheine attachment site K15337 - - 0.000000000000000000000000393 109.0
TLS3_k127_160304_2 COG3321 Polyketide synthase modules and related proteins - - - 0.0 1344.0
TLS3_k127_160304_3 SMART Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase, phosphopantetheine-binding protein - - - 9.454e-223 781.0
TLS3_k127_160304_4 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641,K15311 - 2.3.3.10 1.819e-220 689.0
TLS3_k127_160304_5 Belongs to the beta-ketoacyl-ACP synthases family K00646 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 525.0
TLS3_k127_160304_6 malonyl CoA-acyl carrier protein transacylase K00645,K15355,K15469 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 433.0
TLS3_k127_160304_7 Enoyl-CoA hydratase/isomerase K15312 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 363.0
TLS3_k127_160304_8 enoyl-CoA hydratase K15313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 341.0
TLS3_k127_160304_9 Acyl transferase domain K15328 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 296.0
TLS3_k127_1613129_0 Carboxypeptidase regulatory-like domain - - - 0.0 1303.0
TLS3_k127_1613129_1 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 6.731e-268 830.0
TLS3_k127_1613129_10 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000000003751 189.0
TLS3_k127_1613129_11 PilX N-terminal K02673 - - 0.000000000000000000000000000000000000000000007663 175.0
TLS3_k127_1613129_12 TIGRFAM type IV pilus modification protein PilV K02671 - - 0.000000000000000000000000000000000000004168 153.0
TLS3_k127_1613129_13 Prepilin K08084 - - 0.0000000000000000000000000000009055 139.0
TLS3_k127_1613129_14 - - - - 0.0000000000000000000128 106.0
TLS3_k127_1613129_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 7.028e-201 630.0
TLS3_k127_1613129_3 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 417.0
TLS3_k127_1613129_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 383.0
TLS3_k127_1613129_5 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 373.0
TLS3_k127_1613129_6 UPF0056 membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 332.0
TLS3_k127_1613129_7 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 318.0
TLS3_k127_1613129_8 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001998 273.0
TLS3_k127_1613129_9 - - - - 0.000000000000000000000000000000000000000000000000000000000006218 211.0
TLS3_k127_162939_0 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0 1553.0
TLS3_k127_162939_1 TIGRFAM amino acid adenylation domain K12743 - 6.3.2.26 0.0 1419.0
TLS3_k127_162939_10 response to abiotic stimulus K06867 - - 0.00000000000000000000000000000000000000001926 159.0
TLS3_k127_162939_11 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K02849 - - 0.000000000000000000000000000000000000000706 164.0
TLS3_k127_162939_12 non-ribosomal peptide synthetase - - - 0.000000000000005737 79.0
TLS3_k127_162939_13 FAD-NAD(P)-binding - - - 0.00000000003435 76.0
TLS3_k127_162939_14 Methionine biosynthesis protein MetW - - - 0.0000009986 60.0
TLS3_k127_162939_2 short-chain dehydrogenase reductase SDR K00568 - 2.1.1.222,2.1.1.64 1.638e-277 927.0
TLS3_k127_162939_3 taurine catabolism dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 291.0
TLS3_k127_162939_4 Aspartyl Asparaginyl beta-hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004977 282.0
TLS3_k127_162939_5 Phosphopantetheine attachment site K02364 - 6.3.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000001994 272.0
TLS3_k127_162939_6 Pfam:HxxPF_rpt - - - 0.00000000000000000000000000000000000000000000000000000000000000000006871 260.0
TLS3_k127_162939_7 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000003834 239.0
TLS3_k127_162939_8 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K02849 - - 0.0000000000000000000000000000000000000000000000000000002139 211.0
TLS3_k127_162939_9 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000007721 173.0
TLS3_k127_1634041_0 Lipoprotein releasing system transmembrane protein K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 578.0
TLS3_k127_1634041_1 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000003183 179.0
TLS3_k127_1634041_2 MAPEG family - - - 0.00000000000000000000000000000000000000000008689 164.0
TLS3_k127_1634041_3 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000000000006968 124.0
TLS3_k127_1645886_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 3.324e-214 673.0
TLS3_k127_1645886_1 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000008883 205.0
TLS3_k127_1728988_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005514 262.0
TLS3_k127_1728988_1 LuxR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 248.0
TLS3_k127_1728988_2 - - - - 0.000000000000000000000000000000005083 130.0
TLS3_k127_1728988_3 - - - - 0.000000000000000000003547 101.0
TLS3_k127_1743158_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1771.0
TLS3_k127_1743158_1 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 6.211e-286 892.0
TLS3_k127_1743158_10 regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 355.0
TLS3_k127_1743158_11 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006 269.0
TLS3_k127_1743158_12 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000000000001589 237.0
TLS3_k127_1743158_13 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000009723 236.0
TLS3_k127_1743158_14 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000002 206.0
TLS3_k127_1743158_15 Membrane - - - 0.000000000000000000000000000000000000000000001831 168.0
TLS3_k127_1743158_16 Bacteriophage CI repressor helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000238 162.0
TLS3_k127_1743158_17 - - - - 0.000000000000000000000000000000000001967 143.0
TLS3_k127_1743158_18 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000005858 83.0
TLS3_k127_1743158_19 excinuclease ABC activity - - - 0.0000000000000002545 83.0
TLS3_k127_1743158_2 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 3.948e-272 840.0
TLS3_k127_1743158_20 Bacterial regulatory proteins, tetR family - - - 0.0000002213 62.0
TLS3_k127_1743158_3 Thiol disulfide Interchange Protein K04084 - 1.8.1.8 1.752e-266 851.0
TLS3_k127_1743158_4 Rod shape-determining protein K03569 - - 2.319e-204 639.0
TLS3_k127_1743158_5 Sugar kinase K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 590.0
TLS3_k127_1743158_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 578.0
TLS3_k127_1743158_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 507.0
TLS3_k127_1743158_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 403.0
TLS3_k127_1743158_9 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 370.0
TLS3_k127_1743974_0 Putative methyltransferase - - - 3.578e-281 875.0
TLS3_k127_1743974_1 desaturase K00507 - 1.14.19.1 7.638e-226 703.0
TLS3_k127_1743974_10 RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation K03254 GO:0000003,GO:0001732,GO:0001932,GO:0001933,GO:0002181,GO:0002183,GO:0002188,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005102,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0005852,GO:0005856,GO:0005874,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0007275,GO:0007610,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009790,GO:0009792,GO:0009889,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010563,GO:0010605,GO:0010608,GO:0010646,GO:0010648,GO:0015630,GO:0016032,GO:0016043,GO:0018991,GO:0019080,GO:0019081,GO:0019098,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0023051,GO:0023057,GO:0030971,GO:0031323,GO:0031324,GO:0031326,GO:0031399,GO:0031400,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0034248,GO:0034622,GO:0034641,GO:0034645,GO:0042325,GO:0042326,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043408,GO:0043409,GO:0043603,GO:0043604,GO:0043614,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0045182,GO:0045936,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048609,GO:0048856,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051704,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0070372,GO:0070373,GO:0071540,GO:0071541,GO:0071704,GO:0071826,GO:0071840,GO:0075522,GO:0075525,GO:0080090,GO:0097159,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902531,GO:1902532,GO:1990782,GO:1990904,GO:2000112 - 0.0003834 46.0
TLS3_k127_1743974_2 Dual specificity phosphatase, catalytic domain K01090 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 509.0
TLS3_k127_1743974_3 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 483.0
TLS3_k127_1743974_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002038 296.0
TLS3_k127_1743974_5 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000146 274.0
TLS3_k127_1743974_6 EF hand - - - 0.00000000000000000000000000000002413 138.0
TLS3_k127_1743974_7 Cytochrome C biogenesis protein - - - 0.00000000000000000000000000002592 127.0
TLS3_k127_1743974_9 - - - - 0.000004496 55.0
TLS3_k127_1750528_0 Lipase (class 2) - - - 3.169e-202 639.0
TLS3_k127_1750528_1 Methyltransferase K06983 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 493.0
TLS3_k127_1750528_2 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 451.0
TLS3_k127_1750528_3 Phosphopantetheine attachment site K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 311.0
TLS3_k127_1750528_4 intracellular protease K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000003081 266.0
TLS3_k127_1750528_5 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005292 252.0
TLS3_k127_1750528_6 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000001863 129.0
TLS3_k127_1750528_7 - - - - 0.0000000000000000000000000006991 115.0
TLS3_k127_1788902_0 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 2.28e-303 933.0
TLS3_k127_1788902_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 609.0
TLS3_k127_1788902_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 424.0
TLS3_k127_1788902_3 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 306.0
TLS3_k127_1788902_4 Acetyltransferase (GNAT) domain K03829 - - 0.00000000000000000000000000000000000000000000000000000000000001294 218.0
TLS3_k127_1788902_5 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751 - - 0.000000000000000000000000000000000000000000000000000000002609 203.0
TLS3_k127_1788902_6 Alpha-lytic protease prodomain - - - 0.00000000000009228 78.0
TLS3_k127_1788902_7 Cytochrome p450 - - - 0.0000000000001266 82.0
TLS3_k127_1788902_8 - - - - 0.000000000005649 73.0
TLS3_k127_1810057_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1581.0
TLS3_k127_1810057_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1532.0
TLS3_k127_1810057_10 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K13815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 572.0
TLS3_k127_1810057_11 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 542.0
TLS3_k127_1810057_12 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 529.0
TLS3_k127_1810057_13 enoyl-CoA hydratase K13816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 450.0
TLS3_k127_1810057_14 Response regulator of the LytR AlgR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 412.0
TLS3_k127_1810057_15 helix_turn _helix lactose operon repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 400.0
TLS3_k127_1810057_16 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 377.0
TLS3_k127_1810057_17 Glycosyl hydrolase family 65, C-terminal domain K01838,K05342 - 2.4.1.64,5.4.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 289.0
TLS3_k127_1810057_18 serine-type peptidase activity K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004204 289.0
TLS3_k127_1810057_19 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000000000000000000005957 211.0
TLS3_k127_1810057_2 TonB-dependent receptor - - - 0.0 1229.0
TLS3_k127_1810057_20 SpoVT / AbrB like domain - - - 0.000000000000000000000000000000002031 131.0
TLS3_k127_1810057_21 - - - - 0.000000000000001779 89.0
TLS3_k127_1810057_22 Methylamine utilisation protein MauE - - - 0.000000001484 68.0
TLS3_k127_1810057_23 - - - - 0.0000000113 59.0
TLS3_k127_1810057_24 - - - - 0.00001888 50.0
TLS3_k127_1810057_3 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 7.95e-322 990.0
TLS3_k127_1810057_4 Uncharacterized protein conserved in bacteria (DUF2135) - - - 9.302e-296 940.0
TLS3_k127_1810057_5 Histidine kinase K10715 - 2.7.13.3 1.45e-283 894.0
TLS3_k127_1810057_6 Glycosyl hydrolase family 65, C-terminal domain K01838,K05342 - 2.4.1.64,5.4.2.6 3.047e-283 891.0
TLS3_k127_1810057_7 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 7.426e-278 861.0
TLS3_k127_1810057_8 ABC transporter K06147 - - 4.64e-228 721.0
TLS3_k127_1810057_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 1.042e-196 616.0
TLS3_k127_1815157_0 Amidohydrolase family - - - 2.595e-195 630.0
TLS3_k127_1815157_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 492.0
TLS3_k127_1815157_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 381.0
TLS3_k127_1815157_3 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07693 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 362.0
TLS3_k127_1815157_4 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 314.0
TLS3_k127_1815157_5 Histidine kinase K07778 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001801 287.0
TLS3_k127_1815157_6 ABC transporter K02003 - - 0.00073 44.0
TLS3_k127_1830613_0 Acetamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 596.0
TLS3_k127_1830613_1 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000004006 212.0
TLS3_k127_1830613_2 desaturase K00508 - 1.14.19.3 0.0000000000000000001733 89.0
TLS3_k127_1830781_0 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 460.0
TLS3_k127_1830781_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 395.0
TLS3_k127_1830781_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 372.0
TLS3_k127_1830781_3 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 293.0
TLS3_k127_1830781_4 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000002472 196.0
TLS3_k127_1830781_5 - - - - 0.00000000000000000000000000000000000000007731 162.0
TLS3_k127_1830781_6 - - - - 0.000000000000000000000000004578 124.0
TLS3_k127_183323_0 Belongs to the GPI family K01810 - 5.3.1.9 6.608e-220 697.0
TLS3_k127_183323_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 9.394e-195 615.0
TLS3_k127_183323_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 512.0
TLS3_k127_183323_3 ATPase or kinase K06925 - - 0.00000000000000000000000000000000000000000000000000001528 199.0
TLS3_k127_183323_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000004673 49.0
TLS3_k127_1841519_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 521.0
TLS3_k127_1841519_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 477.0
TLS3_k127_1841519_2 sigma54 specific, transcriptional regulator, Fis family K06714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 476.0
TLS3_k127_1841519_3 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 376.0
TLS3_k127_1841519_4 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 362.0
TLS3_k127_1841519_5 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 321.0
TLS3_k127_1841519_6 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 318.0
TLS3_k127_185221_0 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 522.0
TLS3_k127_185221_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 520.0
TLS3_k127_185221_10 membrane - - - 0.000000000000000000000000000000000000000000000000000000000002045 214.0
TLS3_k127_185221_11 Putative tRNA binding domain - - - 0.00000000000000000000000000000000000000000000000000003748 197.0
TLS3_k127_185221_12 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000002084 164.0
TLS3_k127_185221_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 483.0
TLS3_k127_185221_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 460.0
TLS3_k127_185221_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 421.0
TLS3_k127_185221_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 419.0
TLS3_k127_185221_6 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008697 256.0
TLS3_k127_185221_7 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003383 250.0
TLS3_k127_185221_8 Domain of unknown function (DUF1287) K09974 - - 0.00000000000000000000000000000000000000000000000000000000000000000008004 250.0
TLS3_k127_185221_9 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000000000000000000000005061 227.0
TLS3_k127_1918745_0 involved in the beta-oxidation of n-alkanoic and n-phenylalkanoic acids K01897 - 6.2.1.3 1.722e-213 679.0
TLS3_k127_1918745_1 AAA domain K07028 - - 0.00000000000000000000000000000000000000000006779 176.0
TLS3_k127_1918745_2 Bile acid K03453 - - 0.00000000001202 72.0
TLS3_k127_1922153_0 Cytochrome C biogenesis K02198 - - 4.124e-314 974.0
TLS3_k127_1922153_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 451.0
TLS3_k127_1922153_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 345.0
TLS3_k127_1922153_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 351.0
TLS3_k127_1922153_4 Thiol disulfide interchange protein K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 287.0
TLS3_k127_1922153_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000000001737 220.0
TLS3_k127_1922153_6 Protein of unknown function (DUF3293) - - - 0.0000000000000000000000002831 110.0
TLS3_k127_1922153_7 subunit of a heme lyase K02200 - - 0.0000000000000000000000008212 109.0
TLS3_k127_193437_0 Berberine and berberine like - - - 9.163e-201 639.0
TLS3_k127_193437_1 Monoamine oxidase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 433.0
TLS3_k127_193437_2 COG3547 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 355.0
TLS3_k127_193437_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000173 265.0
TLS3_k127_1934632_0 PFAM TPR repeat-containing protein - - - 8.208e-205 653.0
TLS3_k127_1934632_1 RHS Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 577.0
TLS3_k127_1934965_0 Acts as a magnesium transporter K06213 - - 8.968e-232 724.0
TLS3_k127_1934965_1 Circadian clock protein kaic K08482 - - 9.496e-232 734.0
TLS3_k127_1934965_10 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000003653 153.0
TLS3_k127_1934965_2 alpha amylase, catalytic - - - 3.457e-212 672.0
TLS3_k127_1934965_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 556.0
TLS3_k127_1934965_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 486.0
TLS3_k127_1934965_5 haloacid dehalogenase K18697 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 387.0
TLS3_k127_1934965_6 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 370.0
TLS3_k127_1934965_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 355.0
TLS3_k127_1934965_8 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 336.0
TLS3_k127_1934965_9 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 329.0
TLS3_k127_1935565_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1007.0
TLS3_k127_1935565_1 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 494.0
TLS3_k127_1935565_2 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 467.0
TLS3_k127_1935565_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 364.0
TLS3_k127_1935565_4 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 299.0
TLS3_k127_1935565_5 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003379 239.0
TLS3_k127_1935565_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001415 233.0
TLS3_k127_1935565_7 Lactoylglutathione lyase - - - 0.000000000000000000000000000000000000000000000000000000001942 205.0
TLS3_k127_1935565_8 - - - - 0.00000000000000000000000233 119.0
TLS3_k127_1968870_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1079.0
TLS3_k127_1968870_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - - 0.0 1004.0
TLS3_k127_1968870_2 Castor and Pollux, part of voltage-gated ion channel - - - 3.907e-286 892.0
TLS3_k127_1968870_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.638e-260 808.0
TLS3_k127_1968870_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 593.0
TLS3_k127_1980552_0 Histidine kinase - - - 0.0 1686.0
TLS3_k127_1980552_1 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 377.0
TLS3_k127_1980552_2 - - - - 0.000000000000000000000000004412 116.0
TLS3_k127_2002994_0 Signal transduction histidine kinase K07637 - 2.7.13.3 3.259e-203 643.0
TLS3_k127_2002994_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 557.0
TLS3_k127_2002994_2 protein conserved in bacteria containing a pentein-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 448.0
TLS3_k127_2002994_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 437.0
TLS3_k127_2002994_4 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 379.0
TLS3_k127_2003139_0 Cytochrome C biogenesis K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 331.0
TLS3_k127_2003139_1 interspecies interaction between organisms - - - 0.0000000000000000000000000000000000000000000001694 179.0
TLS3_k127_2003139_2 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000009801 161.0
TLS3_k127_2003139_3 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.0000000000000006551 82.0
TLS3_k127_2009554_0 AMP-binding enzyme C-terminal domain K18661 - - 8.089e-210 668.0
TLS3_k127_2009554_1 ABC-type molybdate transport system periplasmic component K02020 GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0015689,GO:0015698,GO:0030973,GO:0043167,GO:0043168,GO:0051179,GO:0051234,GO:1901359 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002065 279.0
TLS3_k127_2009554_3 transmembrane signaling receptor activity K03406,K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000007635 258.0
TLS3_k127_2009554_4 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000001106 190.0
TLS3_k127_2009554_5 Binding-protein-dependent transport system inner membrane component K02018 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000006196 76.0
TLS3_k127_2009554_6 Oxidoreductase FAD-binding domain K07006 - - 0.0000009983 62.0
TLS3_k127_2009554_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0001935 54.0
TLS3_k127_2031572_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 1.488e-295 930.0
TLS3_k127_2031572_1 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 494.0
TLS3_k127_2031572_2 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A K13481 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 443.0
TLS3_k127_2031572_3 'Xanthine and CO dehydrogenases maturation factor K07402 - - 0.00000000000000000000000000000000000000000002087 174.0
TLS3_k127_2031572_4 HIUase/Transthyretin family K07127 GO:0003674,GO:0005488,GO:0005515,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.2.17 0.0000000000000000000009623 99.0
TLS3_k127_2056173_0 Transporter K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 474.0
TLS3_k127_2056173_1 Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 390.0
TLS3_k127_2056173_2 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000001051 111.0
TLS3_k127_2106513_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1593.0
TLS3_k127_2106513_1 acetyl-coa hydrolase - - - 3.839e-275 861.0
TLS3_k127_2106513_10 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 401.0
TLS3_k127_2106513_11 Acyl transferase domain K00645,K15327,K15329,K15469 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 377.0
TLS3_k127_2106513_13 Outer membrane protein W K07275 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 324.0
TLS3_k127_2106513_14 hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 314.0
TLS3_k127_2106513_15 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 310.0
TLS3_k127_2106513_16 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 316.0
TLS3_k127_2106513_17 S1/P1 Nuclease K05986 - 3.1.30.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 298.0
TLS3_k127_2106513_18 Protein of unknown function (DUF3999) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 303.0
TLS3_k127_2106513_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002484 273.0
TLS3_k127_2106513_2 Predicted membrane protein (DUF2339) - - - 9.893e-269 864.0
TLS3_k127_2106513_20 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001694 264.0
TLS3_k127_2106513_21 RHS Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000724 218.0
TLS3_k127_2106513_22 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000000000000000000000000000000006886 205.0
TLS3_k127_2106513_23 Penicillinase repressor - - - 0.00000000000000000000000000000000000000000000000000003658 190.0
TLS3_k127_2106513_24 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000002771 145.0
TLS3_k127_2106513_25 self proteolysis K17266 - - 0.00000000000000000001287 103.0
TLS3_k127_2106513_27 - - - - 0.00001455 56.0
TLS3_k127_2106513_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.462e-254 791.0
TLS3_k127_2106513_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.615e-212 666.0
TLS3_k127_2106513_5 Domain of Unknown Function with PDB structure (DUF3857) - - - 1.095e-202 653.0
TLS3_k127_2106513_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 9.249e-198 619.0
TLS3_k127_2106513_7 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 575.0
TLS3_k127_2106513_8 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 581.0
TLS3_k127_2106513_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 409.0
TLS3_k127_2133309_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 457.0
TLS3_k127_2133309_1 Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 437.0
TLS3_k127_2133309_10 COG0526 Thiol-disulfide isomerase and thioredoxins K03671 - - 0.00000000000000000000000000000000000004177 147.0
TLS3_k127_2133309_11 - - - - 0.000000000000000000000002068 109.0
TLS3_k127_2133309_12 EF hand - - - 0.0000000000000000000441 94.0
TLS3_k127_2133309_2 Pectate lyase K01728,K21606 - 3.2.1.202,4.2.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 357.0
TLS3_k127_2133309_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 326.0
TLS3_k127_2133309_4 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
TLS3_k127_2133309_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001496 256.0
TLS3_k127_2133309_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000001737 228.0
TLS3_k127_2133309_7 - - - - 0.000000000000000000000000000000000000000000000000000000000004956 222.0
TLS3_k127_2133309_8 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000000000000000000000000000000000000000000000001123 202.0
TLS3_k127_2133309_9 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000005331 194.0
TLS3_k127_2143138_0 polyphosphate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 411.0
TLS3_k127_2143138_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 330.0
TLS3_k127_2143138_2 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 300.0
TLS3_k127_2143138_5 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0000000000000000000000000000000000000000000000000000000002391 205.0
TLS3_k127_2143138_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000005273 166.0
TLS3_k127_2143138_7 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000003819 163.0
TLS3_k127_2143138_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000009418 153.0
TLS3_k127_2151387_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 6.59e-320 998.0
TLS3_k127_2151387_1 hydroxylase K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 532.0
TLS3_k127_2151387_2 acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 434.0
TLS3_k127_2151387_3 adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 316.0
TLS3_k127_2151387_4 Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol K03184,K18800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004044 270.0
TLS3_k127_2151387_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003639 257.0
TLS3_k127_2151387_6 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000002397 110.0
TLS3_k127_2151829_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1046.0
TLS3_k127_2151829_1 signal peptide peptidase K04773 - - 4.733e-281 876.0
TLS3_k127_2151829_10 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005567 278.0
TLS3_k127_2151829_11 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000001303 200.0
TLS3_k127_2151829_12 Zinc metalloprotease (Elastase) K01399,K08604 - 3.4.24.25,3.4.24.26 0.00000000000000000000000000000000000000000000004111 179.0
TLS3_k127_2151829_13 Protein of unknown function (DUF1203) - - - 0.000000000000000000000000000000000000000000006119 172.0
TLS3_k127_2151829_14 - - - - 0.00000000000000000000000000000000000002307 152.0
TLS3_k127_2151829_15 Domain of unknown function (DUF4286) - - - 0.000000000000000000000000000000000006379 139.0
TLS3_k127_2151829_16 - - - - 0.0000003468 55.0
TLS3_k127_2151829_2 Multidrug efflux pump K03327 GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 1.818e-201 637.0
TLS3_k127_2151829_3 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 3.065e-199 630.0
TLS3_k127_2151829_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 630.0
TLS3_k127_2151829_5 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 530.0
TLS3_k127_2151829_6 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 534.0
TLS3_k127_2151829_7 RNA polymerase sigma factor RpoH K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 492.0
TLS3_k127_2151829_8 Tropinone reductase K08081 - 1.1.1.206 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 441.0
TLS3_k127_2151829_9 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 313.0
TLS3_k127_2187656_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.816e-310 955.0
TLS3_k127_2187656_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 537.0
TLS3_k127_2187656_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 482.0
TLS3_k127_2187656_3 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 467.0
TLS3_k127_2187656_4 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 398.0
TLS3_k127_2187656_5 PFAM amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000009985 231.0
TLS3_k127_2187656_6 Domain of unknown function (DUF4190) - - - 0.000000000000000000000000000001178 128.0
TLS3_k127_2187656_7 - - - - 0.00000000000000000000000000516 119.0
TLS3_k127_2205825_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 434.0
TLS3_k127_2205825_1 Predicted membrane protein (DUF2306) - - - 0.000000000000000000000000000000000000001613 160.0
TLS3_k127_2242377_0 Peptidase family M1 domain - - - 0.0 1691.0
TLS3_k127_2242377_1 Putative diguanylate phosphodiesterase - - - 0.0 1127.0
TLS3_k127_2242377_10 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 460.0
TLS3_k127_2242377_11 multivesicular body membrane disassembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 451.0
TLS3_k127_2242377_12 PFAM Gp37Gp68 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 426.0
TLS3_k127_2242377_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 423.0
TLS3_k127_2242377_14 Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 402.0
TLS3_k127_2242377_15 membrane protein (homolog of Drosophila rhomboid) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 332.0
TLS3_k127_2242377_16 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03828 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001979 256.0
TLS3_k127_2242377_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000219 244.0
TLS3_k127_2242377_18 Short-chain dehydrogenase reductase Sdr - - - 0.00000000000000000000000000000000000000000000000000000004026 206.0
TLS3_k127_2242377_19 Domain of unknown function (DUF1820) - - - 0.000000000000000000000000000000000000000000000000001139 184.0
TLS3_k127_2242377_2 carboxylase K01968 - 6.4.1.4 4.145e-279 869.0
TLS3_k127_2242377_20 Excalibur calcium-binding domain - - - 0.0000000000000000000000000000000000000000007697 167.0
TLS3_k127_2242377_21 - - - - 0.00000000000000000000000000000000000317 143.0
TLS3_k127_2242377_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 7.212e-275 852.0
TLS3_k127_2242377_4 aminopeptidase - - - 1.256e-258 810.0
TLS3_k127_2242377_5 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 552.0
TLS3_k127_2242377_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 531.0
TLS3_k127_2242377_7 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 507.0
TLS3_k127_2242377_8 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 496.0
TLS3_k127_2242377_9 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 493.0
TLS3_k127_225055_0 Outer membrane receptor - - - 0.0 1352.0
TLS3_k127_225055_1 protein conserved in bacteria - - - 3.143e-222 699.0
TLS3_k127_225055_2 ABC transporter substrate-binding protein K02027 - - 2.892e-207 651.0
TLS3_k127_225055_3 coagulation factor 5 8 type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 512.0
TLS3_k127_225055_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 507.0
TLS3_k127_225055_5 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 434.0
TLS3_k127_2257220_0 May be involved in recombinational repair of damaged DNA K03631 - - 4.737e-235 740.0
TLS3_k127_2257220_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 522.0
TLS3_k127_2257220_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006574 267.0
TLS3_k127_2257220_3 Oligoketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002829 263.0
TLS3_k127_2257220_4 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000002206 239.0
TLS3_k127_2257220_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000000000000000000000000001017 191.0
TLS3_k127_2257220_6 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000003498 102.0
TLS3_k127_2281808_0 FtsX-like permease family K02004 - - 0.0 1079.0
TLS3_k127_2281808_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.344e-205 684.0
TLS3_k127_2281808_10 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 302.0
TLS3_k127_2281808_11 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001073 257.0
TLS3_k127_2281808_12 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003101 229.0
TLS3_k127_2281808_13 Protein of unknown function (DUF1428) K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000001757 201.0
TLS3_k127_2281808_14 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.0000000000000000000000000000000000000000000000000005252 186.0
TLS3_k127_2281808_15 YCII-related domain - - - 0.000000000000000000000000000000000000000000000001313 179.0
TLS3_k127_2281808_16 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.0000000000000000000000000000000000000000001215 162.0
TLS3_k127_2281808_17 - - - - 0.000000000000000000000000000000000000000001388 159.0
TLS3_k127_2281808_18 Bacteriophage CI repressor helix-turn-helix domain - - - 0.0000000000000000000000000000000001535 138.0
TLS3_k127_2281808_19 Domain of unknown function (DUF4287) - - - 0.0000000000000000000000000000012 125.0
TLS3_k127_2281808_2 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 596.0
TLS3_k127_2281808_20 Thermostable hemolysin - - - 0.000000000000000000000004041 105.0
TLS3_k127_2281808_21 YCII-related domain - - - 0.000000000000000000000006304 105.0
TLS3_k127_2281808_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 436.0
TLS3_k127_2281808_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 437.0
TLS3_k127_2281808_5 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 449.0
TLS3_k127_2281808_6 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 388.0
TLS3_k127_2281808_7 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 373.0
TLS3_k127_2281808_8 Ami_2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 368.0
TLS3_k127_2281808_9 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 350.0
TLS3_k127_2283189_0 Required for chromosome condensation and partitioning K03529 - - 8.696e-195 612.0
TLS3_k127_2283189_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 299.0
TLS3_k127_2284930_0 lacI family K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 403.0
TLS3_k127_2284930_1 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 315.0
TLS3_k127_2318136_0 AAA ATPase domain - - - 3.763e-264 818.0
TLS3_k127_2318136_1 Protein of unknown function (DUF1631) - - - 1.124e-242 779.0
TLS3_k127_2318136_10 PilZ domain - - - 0.000000000000000000000000000000000005813 140.0
TLS3_k127_2318136_11 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.000000000000000000000000000000000009127 142.0
TLS3_k127_2318136_12 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000008041 72.0
TLS3_k127_2318136_2 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 9.412e-232 729.0
TLS3_k127_2318136_3 Involved in the biosynthesis of porphyrin-containing compound - - - 1.241e-203 639.0
TLS3_k127_2318136_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 423.0
TLS3_k127_2318136_5 stress-induced protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008282 385.0
TLS3_k127_2318136_6 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 349.0
TLS3_k127_2318136_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 289.0
TLS3_k127_2318136_8 Chitinase class I - - - 0.000000000000000000000000000000000000000000000000000000000000000009878 243.0
TLS3_k127_2318136_9 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000009813 180.0
TLS3_k127_2369401_0 Lamin Tail Domain K07004 - - 5.197e-274 886.0
TLS3_k127_2369401_1 Transporter K03305 - - 2.863e-255 796.0
TLS3_k127_2369401_10 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006916 281.0
TLS3_k127_2369401_11 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000005232 196.0
TLS3_k127_2369401_12 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000127 184.0
TLS3_k127_2369401_13 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000005885 168.0
TLS3_k127_2369401_14 Src homology 3 domains - - - 0.0000000000000000000000000000000000000003371 155.0
TLS3_k127_2369401_15 - - - - 0.000000000000000000000000000000000000422 145.0
TLS3_k127_2369401_16 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000734 139.0
TLS3_k127_2369401_17 Glutaredoxin K07390 - - 0.0000000000000000000000001627 120.0
TLS3_k127_2369401_18 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.0000000000000000000001375 113.0
TLS3_k127_2369401_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 2.728e-215 678.0
TLS3_k127_2369401_3 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 6.048e-204 640.0
TLS3_k127_2369401_4 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 1.934e-194 610.0
TLS3_k127_2369401_5 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 619.0
TLS3_k127_2369401_6 aminotransferase K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 582.0
TLS3_k127_2369401_7 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 497.0
TLS3_k127_2369401_8 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 347.0
TLS3_k127_2369401_9 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 299.0
TLS3_k127_2424069_0 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 310.0
TLS3_k127_2424069_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003093 253.0
TLS3_k127_2424069_2 Outer membrane lipoprotein K07285 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001296 253.0
TLS3_k127_2424069_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002327 234.0
TLS3_k127_2424069_4 2OG-Fe(II) oxygenase superfamily K07394 - - 0.00000000000000000000000000000000000000000000000000000000000004355 226.0
TLS3_k127_2424069_6 Cysteine methyltransferase K07443 - - 0.00000000000000000000000000000000008571 137.0
TLS3_k127_2435996_0 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0 1169.0
TLS3_k127_2435996_1 AMP-binding enzyme C-terminal domain K00666 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 571.0
TLS3_k127_2435996_2 Acyl-CoA dehydrogenase, C-terminal domain K00257 GO:0003674,GO:0003824,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009237,GO:0009712,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0016631,GO:0018958,GO:0019184,GO:0019290,GO:0019540,GO:0019748,GO:0034641,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044550,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901615 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 413.0
TLS3_k127_2435996_3 oxidoreductase K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 384.0
TLS3_k127_2435996_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007683 282.0
TLS3_k127_2435996_5 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001836 209.0
TLS3_k127_2435996_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000001364 189.0
TLS3_k127_2435996_7 acyl carrier protein K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006518,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009237,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009712,GO:0009987,GO:0016051,GO:0016053,GO:0018958,GO:0019184,GO:0019290,GO:0019540,GO:0019637,GO:0019748,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0034641,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051186,GO:0051188,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1903509 - 0.000000000000000001707 87.0
TLS3_k127_2435996_8 - - - - 0.0001124 47.0
TLS3_k127_2471751_0 Large extracellular alpha-helical protein K06894 - - 0.0 1712.0
TLS3_k127_2471751_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.507e-303 938.0
TLS3_k127_2561035_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 2.318e-214 669.0
TLS3_k127_2561035_1 COG0457 FOG TPR repeat - - - 1.039e-204 652.0
TLS3_k127_2561035_10 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000006274 182.0
TLS3_k127_2561035_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 595.0
TLS3_k127_2561035_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 574.0
TLS3_k127_2561035_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 568.0
TLS3_k127_2561035_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 411.0
TLS3_k127_2561035_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 348.0
TLS3_k127_2561035_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 344.0
TLS3_k127_2561035_8 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001585 278.0
TLS3_k127_2561035_9 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000000000000000000000000000000000000000004419 216.0
TLS3_k127_2580581_0 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.0 1251.0
TLS3_k127_2580581_1 chemotaxis protein K02660 - - 0.0 1102.0
TLS3_k127_2580581_2 chemotaxis signal transduction protein K02659 - - 0.0000000000000000000000005158 104.0
TLS3_k127_2608156_0 DNA mismatch repair - - - 1.772e-306 955.0
TLS3_k127_2608156_1 Peptide synthase K22319 - 6.1.3.1 3.963e-275 855.0
TLS3_k127_2608156_2 Trypsin-like peptidase domain K01337 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 569.0
TLS3_k127_2608156_3 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 496.0
TLS3_k127_2608156_4 Alpha beta K22318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 488.0
TLS3_k127_2608156_5 Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 456.0
TLS3_k127_2608156_6 Type II restriction enzyme, methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005594 276.0
TLS3_k127_2608156_7 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000438 246.0
TLS3_k127_2608156_8 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000009797 247.0
TLS3_k127_261404_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1034.0
TLS3_k127_261404_1 Bacterial protein of unknown function (DUF885) - - - 4.039e-285 894.0
TLS3_k127_261404_2 Protein of unknown function (DUF2785) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 389.0
TLS3_k127_261404_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 242.0
TLS3_k127_261404_4 cheY-homologous receiver domain K02658 - - 0.00000000000000000000000000000000000000000000000000000000008704 211.0
TLS3_k127_261404_5 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000195 210.0
TLS3_k127_2620674_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 2.615e-216 703.0
TLS3_k127_2620674_1 Histidine kinase - - - 5.245e-204 642.0
TLS3_k127_2620674_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 1.21e-202 641.0
TLS3_k127_2620674_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 519.0
TLS3_k127_2620674_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 441.0
TLS3_k127_2620674_5 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 404.0
TLS3_k127_2625655_0 Sodium/hydrogen exchanger family - - - 3.742e-201 633.0
TLS3_k127_2625655_1 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 611.0
TLS3_k127_2625655_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 568.0
TLS3_k127_2625655_3 Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 561.0
TLS3_k127_2625655_4 murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 505.0
TLS3_k127_2625655_5 amino acid adenylation domain protein K04780 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 363.0
TLS3_k127_2625655_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 363.0
TLS3_k127_2625655_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 330.0
TLS3_k127_2625655_8 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000002256 194.0
TLS3_k127_2625655_9 - - - - 0.000000000000000000000000000000000000000000005018 165.0
TLS3_k127_2643906_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 3.586e-267 854.0
TLS3_k127_2643906_1 Domain of unknown function (DUF3459) K01176 - 3.2.1.1 3.066e-237 751.0
TLS3_k127_2643906_2 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 486.0
TLS3_k127_2643906_3 Transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 349.0
TLS3_k127_2643906_4 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 287.0
TLS3_k127_2643906_5 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000000000000000000000000008816 231.0
TLS3_k127_2643906_6 - - - - 0.00000000000000000000000000000000000000000000000000008691 189.0
TLS3_k127_2643906_7 - - - - 0.0000000000000000000000000000000000000000003554 167.0
TLS3_k127_2643906_8 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.00000000000000000000000000000000000000001425 175.0
TLS3_k127_2712486_0 DNA-sulfur modification-associated K19169 - - 1.84e-241 768.0
TLS3_k127_2712486_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 540.0
TLS3_k127_2712486_10 Zinc finger, swim domain protein - - - 0.000000000000000000000000000000000000000001674 181.0
TLS3_k127_2712486_11 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000000000001184 158.0
TLS3_k127_2712486_12 - - - - 0.00000000000000000007099 94.0
TLS3_k127_2712486_2 PFAM ATPase associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 495.0
TLS3_k127_2712486_3 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 455.0
TLS3_k127_2712486_4 VWA domain containing CoxE-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 403.0
TLS3_k127_2712486_5 Domain of unknown function (DUF4132) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 316.0
TLS3_k127_2712486_6 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007092 287.0
TLS3_k127_2712486_7 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000222 207.0
TLS3_k127_2712486_8 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000122 188.0
TLS3_k127_2712486_9 Virulence regulator - - - 0.0000000000000000000000000000000000000000000001303 173.0
TLS3_k127_2728169_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 3.116e-291 899.0
TLS3_k127_2791764_0 Outer membrane receptor proteins mostly Fe transport K02014 - - 3.277e-291 918.0
TLS3_k127_2791764_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.054e-248 773.0
TLS3_k127_2791764_10 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 364.0
TLS3_k127_2791764_11 Belongs to the Fur family K09823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004304 266.0
TLS3_k127_2791764_12 WHG domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001578 258.0
TLS3_k127_2791764_13 MerC mercury resistance protein - - - 0.00000000000000000000000000000000000000000000000000000001514 201.0
TLS3_k127_2791764_14 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000005635 220.0
TLS3_k127_2791764_15 Ribosomal protein S31e K19033 - - 0.0000000000004801 72.0
TLS3_k127_2791764_16 - - - - 0.000000005027 61.0
TLS3_k127_2791764_2 AlkA N-terminal domain K13529 - 3.2.2.21 1.414e-209 663.0
TLS3_k127_2791764_3 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 1.222e-200 652.0
TLS3_k127_2791764_4 deiminase K05603 - 3.5.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 592.0
TLS3_k127_2791764_5 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 528.0
TLS3_k127_2791764_6 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 491.0
TLS3_k127_2791764_7 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 464.0
TLS3_k127_2791764_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 421.0
TLS3_k127_2791764_9 proteins of the AP superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 411.0
TLS3_k127_2798206_0 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 434.0
TLS3_k127_2798206_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 421.0
TLS3_k127_2798206_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 419.0
TLS3_k127_2798206_3 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 389.0
TLS3_k127_2798206_4 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 387.0
TLS3_k127_2798206_5 Catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate K22292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 292.0
TLS3_k127_2798206_6 Phytoene synthase - - - 0.000000000000000000000000000000000000000006874 171.0
TLS3_k127_2802333_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.378e-239 745.0
TLS3_k127_2802333_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 511.0
TLS3_k127_2802333_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000007426 224.0
TLS3_k127_2802333_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000001631 122.0
TLS3_k127_2805002_0 Efflux pump membrane transporter K19585 - - 0.0 1778.0
TLS3_k127_2805002_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1754.0
TLS3_k127_2805002_10 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 501.0
TLS3_k127_2805002_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 380.0
TLS3_k127_2805002_12 endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 346.0
TLS3_k127_2805002_13 TraB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 327.0
TLS3_k127_2805002_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 314.0
TLS3_k127_2805002_15 Putative esterase K07017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001305 285.0
TLS3_k127_2805002_16 lipocalin K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000001342 240.0
TLS3_k127_2805002_17 MerR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000001627 228.0
TLS3_k127_2805002_18 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002165 209.0
TLS3_k127_2805002_19 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000000000000001007 193.0
TLS3_k127_2805002_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1176.0
TLS3_k127_2805002_20 - - - - 0.00000000000000000000000000000000000000000000000001065 184.0
TLS3_k127_2805002_21 luxR family - - - 0.000000000000000000000000000000000000000000000001031 194.0
TLS3_k127_2805002_22 short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000008546 186.0
TLS3_k127_2805002_23 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000001427 130.0
TLS3_k127_2805002_24 Lipase (class 3) - - - 0.000000000000001993 90.0
TLS3_k127_2805002_25 Putative peptidoglycan binding domain K03791 - - 0.000002364 55.0
TLS3_k127_2805002_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1110.0
TLS3_k127_2805002_4 acyl-coa dehydrogenase - - - 4.29e-297 933.0
TLS3_k127_2805002_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 603.0
TLS3_k127_2805002_6 COG0845 Membrane-fusion protein K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 599.0
TLS3_k127_2805002_7 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 568.0
TLS3_k127_2805002_8 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 550.0
TLS3_k127_2805002_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298,K19586 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 544.0
TLS3_k127_2822986_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1732.0
TLS3_k127_2822986_1 Belongs to the peptidase S8 family K14645 - - 1.468e-275 874.0
TLS3_k127_2822986_2 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000002535 200.0
TLS3_k127_2822986_3 chlorophyll binding K03286,K16191 - - 0.0000000000000000000000000000000000000000809 163.0
TLS3_k127_2826849_0 membrane - - - 0.0 1320.0
TLS3_k127_2826849_1 Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD K03592 - - 5.564e-196 618.0
TLS3_k127_2826849_2 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 1.303e-194 621.0
TLS3_k127_2826849_3 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 584.0
TLS3_k127_2826849_4 NADH flavin oxidoreductase NADH oxidase K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 573.0
TLS3_k127_2826849_5 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 320.0
TLS3_k127_2826849_6 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000097 257.0
TLS3_k127_2826849_7 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000000000000000000000000000000000004095 233.0
TLS3_k127_2826849_8 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000004138 166.0
TLS3_k127_2834021_0 Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1903.0
TLS3_k127_2834021_1 Single-stranded-DNA-specific exonuclease K07462 - - 1.147e-235 758.0
TLS3_k127_2834021_2 - - - - 4.89e-221 702.0
TLS3_k127_2834021_3 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 6.511e-217 679.0
TLS3_k127_2834021_4 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 457.0
TLS3_k127_2834021_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 311.0
TLS3_k127_2834021_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 314.0
TLS3_k127_2834021_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000001035 256.0
TLS3_k127_2834021_9 - - - - 0.0000000000000000000000000000000000000001923 163.0
TLS3_k127_2843515_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1089.0
TLS3_k127_2843515_1 converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP K01953 - 6.3.5.4 1.545e-315 974.0
TLS3_k127_2843515_10 ArsC family - - - 0.0000000000000000000000000000000000000000000000000000000000000002209 221.0
TLS3_k127_2843515_11 Pilus assembly protein K07346 - - 0.0000000000000000000000000000000000000000000000000000000000000004256 228.0
TLS3_k127_2843515_12 Spore Coat Protein U domain - - - 0.0000000000000000000000000000000000000000000000004645 184.0
TLS3_k127_2843515_13 - - - - 0.00000000000000000001109 105.0
TLS3_k127_2843515_14 Sel1-like repeats. - - - 0.0004509 46.0
TLS3_k127_2843515_2 outer membrane usher protein K07347 - - 4.648e-235 754.0
TLS3_k127_2843515_3 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 2.821e-214 671.0
TLS3_k127_2843515_4 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 495.0
TLS3_k127_2843515_5 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 481.0
TLS3_k127_2843515_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 466.0
TLS3_k127_2843515_7 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 460.0
TLS3_k127_2843515_8 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 358.0
TLS3_k127_2843515_9 Spore Coat Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 343.0
TLS3_k127_2866632_0 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 559.0
TLS3_k127_2866632_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 512.0
TLS3_k127_2866632_2 Flavin reductase like domain - - - 0.0000000000000003667 78.0
TLS3_k127_2866632_3 - - - - 0.00000000002752 69.0
TLS3_k127_2866632_4 - - - - 0.0000000001028 68.0
TLS3_k127_2866632_5 Membrane - - - 0.000006434 48.0
TLS3_k127_2878005_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1149.0
TLS3_k127_2878005_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0 1056.0
TLS3_k127_2878005_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.298e-267 840.0
TLS3_k127_2878005_3 alkylated DNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000179 271.0
TLS3_k127_2878005_4 endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000001252 194.0
TLS3_k127_2878005_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000000000000000001127 183.0
TLS3_k127_2878005_6 transcriptional - - - 0.00000000000000000000000000000000003084 140.0
TLS3_k127_2878005_7 Rhodanese Homology Domain - - - 0.0000000000000000003495 87.0
TLS3_k127_2878005_8 multivesicular body membrane disassembly - - - 0.000051 56.0
TLS3_k127_2896069_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 600.0
TLS3_k127_2896069_1 TRANSFER OF ELECTRONS FROM NADH TO THE RESPIRATORY CHAIN. THE IMMEDIATE ELECTRON ACCEPTOR FOR THE ENZYME IS BELIEVED TO BE UBIQUINONE. DOES NOT COUPLE THE REDOX REACTION TO PROTON TRANSLOCATION. Interpro FAD-dependent pyridine K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 340.0
TLS3_k127_2896069_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 287.0
TLS3_k127_2896069_3 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000003116 108.0
TLS3_k127_2908453_0 AMP-dependent synthetase - - - 0.0 1545.0
TLS3_k127_2908453_1 Pfam:NRPS K16395 - - 0.0 1251.0
TLS3_k127_2908453_10 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000232 292.0
TLS3_k127_2908453_11 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009693 258.0
TLS3_k127_2908453_12 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006887 252.0
TLS3_k127_2908453_13 abc transporter atp-binding protein K06159,K06160 - - 0.0000000000000000000000000000000000000000000000000000000005983 223.0
TLS3_k127_2908453_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.000000000000000000000000000000000000000000000000000000001517 215.0
TLS3_k127_2908453_15 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000009061 187.0
TLS3_k127_2908453_16 MgtC family K07507 - - 0.00000000000000000000000000000000000000000000001155 175.0
TLS3_k127_2908453_17 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000001793 166.0
TLS3_k127_2908453_18 Urease accessory protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000002288 164.0
TLS3_k127_2908453_19 Cupin-like domain - - - 0.000000000000000000000000000000000001041 152.0
TLS3_k127_2908453_2 COG3321 Polyketide synthase modules and related proteins - - - 0.0 1116.0
TLS3_k127_2908453_20 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000001187 153.0
TLS3_k127_2908453_21 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000003303 144.0
TLS3_k127_2908453_22 Formyl transferase - - - 0.0000000000000000000001767 106.0
TLS3_k127_2908453_25 SnoaL-like domain - - - 0.0000000592 63.0
TLS3_k127_2908453_3 Non-ribosomal peptide synthetase modules and related proteins - - - 1.167e-293 950.0
TLS3_k127_2908453_4 receptor - - - 4.826e-268 845.0
TLS3_k127_2908453_5 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 607.0
TLS3_k127_2908453_6 Condensation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 640.0
TLS3_k127_2908453_7 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 445.0
TLS3_k127_2908453_8 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 426.0
TLS3_k127_2908453_9 amino acid adenylation domain protein K04780 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 329.0
TLS3_k127_2930318_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 3.305e-236 736.0
TLS3_k127_2930318_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 286.0
TLS3_k127_2931673_0 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 393.0
TLS3_k127_2931673_1 Membrane K07027 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000008077 241.0
TLS3_k127_2957000_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1225.0
TLS3_k127_2957000_1 Methyltransferase K00558 - 2.1.1.37 9.166e-215 673.0
TLS3_k127_2957000_10 May nick specific sequences that contain T G mispairs resulting from m5C-deamination K07458 - - 0.0000000000000000000000000000000000000000000000000005836 189.0
TLS3_k127_2957000_11 Domain of unknown function (DUF3817) - - - 0.0000000000000000000000000000000000000000000000001235 182.0
TLS3_k127_2957000_12 Peptidase propeptide and YPEB domain - - - 0.000000000000000000000000000000000000000000007539 168.0
TLS3_k127_2957000_13 - - - - 0.000000000000000000000000000000000000007661 151.0
TLS3_k127_2957000_14 Winged helix DNA-binding domain K09927 - - 0.000000000001598 69.0
TLS3_k127_2957000_15 adventurous gliding protein T - - - 0.000001989 61.0
TLS3_k127_2957000_16 His Kinase A (phosphoacceptor) domain - - - 0.0000046 60.0
TLS3_k127_2957000_17 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0002103 45.0
TLS3_k127_2957000_2 Specifically methylates the adenine in position 1618 of 23S rRNA K06970 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 443.0
TLS3_k127_2957000_3 PAAR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 431.0
TLS3_k127_2957000_4 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 396.0
TLS3_k127_2957000_5 MvaI/BcnI restriction endonuclease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 364.0
TLS3_k127_2957000_6 Belongs to the GPAT DAPAT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 297.0
TLS3_k127_2957000_7 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005847 297.0
TLS3_k127_2957000_8 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001105 259.0
TLS3_k127_2957000_9 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate K07559 - - 0.00000000000000000000000000000000000000000000000000000000000007121 237.0
TLS3_k127_2958558_0 PA domain - - - 0.0 1115.0
TLS3_k127_2958558_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - - 2.041e-194 613.0
TLS3_k127_2958558_2 MFS transporter permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 387.0
TLS3_k127_2958558_3 arsR family K03892 - - 0.000000000000000000000000000000000000001345 153.0
TLS3_k127_2959551_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.0 1139.0
TLS3_k127_2959551_1 Helicase K03722 - 3.6.4.12 1.24e-322 1010.0
TLS3_k127_2959551_10 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 402.0
TLS3_k127_2959551_11 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 375.0
TLS3_k127_2959551_12 glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001551 275.0
TLS3_k127_2959551_13 Yip1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005778 263.0
TLS3_k127_2959551_14 chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008511 261.0
TLS3_k127_2959551_15 response regulator K02657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004786 251.0
TLS3_k127_2959551_16 Signal peptidase, peptidase S26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000112 248.0
TLS3_k127_2959551_17 response K02658 - - 0.000000000000000000000000000000000000000000000000000000000006178 210.0
TLS3_k127_2959551_18 - - - - 0.000000000000000000000000000000000000000000000000000000004667 203.0
TLS3_k127_2959551_19 Tetratricopeptide repeat - - - 0.00000000000000000000000000000006979 143.0
TLS3_k127_2959551_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.493e-306 955.0
TLS3_k127_2959551_20 - K03655 - 3.6.4.12 0.00000000000001943 84.0
TLS3_k127_2959551_3 Glycosyl transferase K20444 - - 1.233e-295 928.0
TLS3_k127_2959551_4 Helicase K03578 - 3.6.4.13 1.16e-292 908.0
TLS3_k127_2959551_5 chemotaxis protein K02660 - - 1.119e-270 846.0
TLS3_k127_2959551_6 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 576.0
TLS3_k127_2959551_7 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 511.0
TLS3_k127_2959551_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 431.0
TLS3_k127_2959551_9 tonb protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 398.0
TLS3_k127_2975450_0 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 413.0
TLS3_k127_2975450_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 315.0
TLS3_k127_2975450_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 273.0
TLS3_k127_2975450_3 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000003367 227.0
TLS3_k127_2975450_4 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000007606 115.0
TLS3_k127_2975450_5 - - - - 0.0003525 44.0
TLS3_k127_3012539_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1063.0
TLS3_k127_3012539_1 TonB-dependent Receptor Plug Domain K02014 - - 7.352e-282 888.0
TLS3_k127_3012539_2 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 530.0
TLS3_k127_3012539_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 485.0
TLS3_k127_3012539_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 354.0
TLS3_k127_3012539_5 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000000000000287 177.0
TLS3_k127_3012539_6 Peptidase M15 - - - 0.00000000000000000000000000000000000000000002756 168.0
TLS3_k127_3012539_7 RNA-binding protein K07574 - - 0.000000000000000000000000000000000000006482 150.0
TLS3_k127_3012539_8 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.000000000000000000000000000000002318 133.0
TLS3_k127_3027427_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1173.0
TLS3_k127_3027427_1 COG0477 Permeases of the major facilitator superfamily - - - 5.987e-302 933.0
TLS3_k127_3027427_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 419.0
TLS3_k127_3027427_11 Peptidase inhibitor I9 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 406.0
TLS3_k127_3027427_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 371.0
TLS3_k127_3027427_13 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 358.0
TLS3_k127_3027427_14 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 346.0
TLS3_k127_3027427_15 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 321.0
TLS3_k127_3027427_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 304.0
TLS3_k127_3027427_17 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 295.0
TLS3_k127_3027427_18 Tryptophan-rich sensory protein K05770 - - 0.00000000000000000000000000000000000000000000000000000000000000005602 231.0
TLS3_k127_3027427_19 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000000000001065 199.0
TLS3_k127_3027427_2 Sigma-54 interaction domain - - - 1.67e-221 704.0
TLS3_k127_3027427_20 - - - - 0.00000000000000000000000000000000000000000000002463 184.0
TLS3_k127_3027427_21 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000001804 121.0
TLS3_k127_3027427_22 Protein of unknown function (DUF465) - - - 0.0000000000000000000000000234 110.0
TLS3_k127_3027427_23 bacterial OsmY and nodulation domain K04065 - - 0.00000000000000000000000009258 117.0
TLS3_k127_3027427_24 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000000000008512 113.0
TLS3_k127_3027427_25 - - - - 0.00000000000000000000002306 105.0
TLS3_k127_3027427_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000004171 93.0
TLS3_k127_3027427_27 Protein of unknown function (DUF1328) - - - 0.00000000000000001503 83.0
TLS3_k127_3027427_3 His Kinase A (phosphoacceptor) domain - - - 5.481e-216 693.0
TLS3_k127_3027427_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 3.54e-197 625.0
TLS3_k127_3027427_5 glycine D-amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 560.0
TLS3_k127_3027427_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 496.0
TLS3_k127_3027427_7 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 492.0
TLS3_k127_3027427_8 May be involved in recombination K03554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 471.0
TLS3_k127_3027427_9 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 449.0
TLS3_k127_3045698_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.395e-235 742.0
TLS3_k127_3045698_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 508.0
TLS3_k127_3045698_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 492.0
TLS3_k127_3045698_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000009413 266.0
TLS3_k127_3059008_0 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0 1601.0
TLS3_k127_3060698_0 receptor K16092 - - 1.361e-242 767.0
TLS3_k127_3060698_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 462.0
TLS3_k127_3060698_2 Diguanylate cyclase K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000000000000000000000000000009835 246.0
TLS3_k127_3060698_3 regulator - - - 0.00000000000000000000000000000000000000000000000000003951 192.0
TLS3_k127_3081377_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1171.0
TLS3_k127_3081377_1 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 9.672e-238 744.0
TLS3_k127_3081377_10 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000102 265.0
TLS3_k127_3081377_11 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000001397 243.0
TLS3_k127_3081377_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000269 225.0
TLS3_k127_3081377_13 PIN domain K07064 - - 0.00000000000000000000000000000000000000000003475 168.0
TLS3_k127_3081377_14 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000000001609 153.0
TLS3_k127_3081377_15 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000854 125.0
TLS3_k127_3081377_17 - - - - 0.000000007438 57.0
TLS3_k127_3081377_18 Histidine kinase K07641 - 2.7.13.3 0.00000001131 56.0
TLS3_k127_3081377_2 Histidine kinase K07636 - 2.7.13.3 1.241e-213 670.0
TLS3_k127_3081377_20 - - - - 0.0000003954 53.0
TLS3_k127_3081377_21 - - - - 0.0006629 48.0
TLS3_k127_3081377_3 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 4.111e-203 655.0
TLS3_k127_3081377_4 Catalyzes the formation of 2-oxoglutarate from isocitrate K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 602.0
TLS3_k127_3081377_5 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 535.0
TLS3_k127_3081377_6 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 504.0
TLS3_k127_3081377_7 Two component response regulator for the phosphate regulon K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 423.0
TLS3_k127_3081377_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 400.0
TLS3_k127_3081377_9 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 420.0
TLS3_k127_3083363_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 1.784e-259 809.0
TLS3_k127_3083363_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0050311,GO:0055114 1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 439.0
TLS3_k127_3083363_2 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 414.0
TLS3_k127_3083363_3 Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol K03184,K18800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 292.0
TLS3_k127_3083363_4 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003257 240.0
TLS3_k127_3128513_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1167.0
TLS3_k127_3128513_1 Alkyl hydroperoxide reductase K03387 - - 2.036e-254 800.0
TLS3_k127_3128513_10 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 288.0
TLS3_k127_3128513_11 pilus assembly protein pilp K02665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004493 268.0
TLS3_k127_3128513_12 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002857 263.0
TLS3_k127_3128513_13 assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002875 259.0
TLS3_k127_3128513_14 Protein of unknown function (DUF1294) - - - 0.000000000000000000000000000000000000000000000000000006856 196.0
TLS3_k127_3128513_15 Domain of unknown function (DUF4381) - - - 0.000000000000000000000000000000000085 151.0
TLS3_k127_3128513_2 Type II secretory pathway, component HofQ K02666 - - 3.109e-230 730.0
TLS3_k127_3128513_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 2.072e-198 621.0
TLS3_k127_3128513_4 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 608.0
TLS3_k127_3128513_5 ATPase (AAA K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 531.0
TLS3_k127_3128513_6 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 413.0
TLS3_k127_3128513_7 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 364.0
TLS3_k127_3128513_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 353.0
TLS3_k127_3128513_9 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 324.0
TLS3_k127_3296249_0 Malic enzyme K00029 - 1.1.1.40 0.0 1330.0
TLS3_k127_3296249_1 protein conserved in bacteria - - - 9.309e-217 679.0
TLS3_k127_3296249_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 304.0
TLS3_k127_3325984_0 Asparagine synthase K01953 - 6.3.5.4 1.487e-320 993.0
TLS3_k127_3325984_1 xylan catabolic process K03932 - - 3.375e-257 812.0
TLS3_k127_3325984_10 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 396.0
TLS3_k127_3325984_11 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 388.0
TLS3_k127_3325984_12 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 369.0
TLS3_k127_3325984_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 373.0
TLS3_k127_3325984_14 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 346.0
TLS3_k127_3325984_15 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 346.0
TLS3_k127_3325984_16 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 346.0
TLS3_k127_3325984_17 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 334.0
TLS3_k127_3325984_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 293.0
TLS3_k127_3325984_19 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008413 274.0
TLS3_k127_3325984_2 alpha-amylase K01176 - 3.2.1.1 2.855e-210 666.0
TLS3_k127_3325984_20 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002774 268.0
TLS3_k127_3325984_21 general stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002024 232.0
TLS3_k127_3325984_22 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000006595 239.0
TLS3_k127_3325984_23 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000001489 211.0
TLS3_k127_3325984_24 PhnA domain K06193 - - 0.000000000000000000000000000000000000000000000002721 177.0
TLS3_k127_3325984_25 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000001642 184.0
TLS3_k127_3325984_26 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000000001823 171.0
TLS3_k127_3325984_27 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000014 177.0
TLS3_k127_3325984_28 TIGRFAM phage conjugal plasmid C-4 type zinc finger protein, TraR family - - - 0.0000000000000000000000000000000000000000005403 158.0
TLS3_k127_3325984_29 methyltransferase - - - 0.000000000000000000000000000962 125.0
TLS3_k127_3325984_3 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 584.0
TLS3_k127_3325984_30 - - - - 0.000000000000000000000000001525 117.0
TLS3_k127_3325984_31 Acyl carrier protein - - - 0.0000000000000000000003976 111.0
TLS3_k127_3325984_32 COG3668 Plasmid stabilization system protein - - - 0.0000000000000000002721 91.0
TLS3_k127_3325984_33 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000001164 89.0
TLS3_k127_3325984_34 - - - - 0.00000000000000005367 94.0
TLS3_k127_3325984_35 Protein conserved in bacteria - - - 0.0000000000000002073 80.0
TLS3_k127_3325984_36 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000003288 61.0
TLS3_k127_3325984_5 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 524.0
TLS3_k127_3325984_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 508.0
TLS3_k127_3325984_7 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 515.0
TLS3_k127_3325984_8 Glucose / Sorbosone dehydrogenase K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 466.0
TLS3_k127_3325984_9 Lipoprotein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 424.0
TLS3_k127_338390_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 531.0
TLS3_k127_338390_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001591 280.0
TLS3_k127_338390_2 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000001357 244.0
TLS3_k127_338390_3 - - - - 0.00000000000000000000000000000000000000000000004543 176.0
TLS3_k127_338390_4 ferredoxin - - - 0.000000000000000000000000000000001565 132.0
TLS3_k127_338390_5 Protein involved in outer membrane biogenesis - - - 0.00000000000312 77.0
TLS3_k127_3419434_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1868.0
TLS3_k127_3419434_1 Histidine kinase K07641 - 2.7.13.3 3.718e-206 651.0
TLS3_k127_3419434_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004568 255.0
TLS3_k127_3419434_11 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.000000000000000000000000000000000000000000000006232 179.0
TLS3_k127_3419434_12 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000006781 158.0
TLS3_k127_3419434_13 - - - - 0.0000000000000000000000000000000000000217 150.0
TLS3_k127_3419434_14 YjbR - - - 0.00000000000000000000000000000001136 130.0
TLS3_k127_3419434_2 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis K03196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 599.0
TLS3_k127_3419434_3 Protein of unknown function (DUF808) K09781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 434.0
TLS3_k127_3419434_4 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 400.0
TLS3_k127_3419434_5 Bacterial conjugation TrbI-like protein K03195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 398.0
TLS3_k127_3419434_6 Type IV secretory pathway, VirB9 K03204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 365.0
TLS3_k127_3419434_7 response regulator K07663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 329.0
TLS3_k127_3419434_8 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 282.0
TLS3_k127_3419434_9 VirB8 protein K03203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004606 284.0
TLS3_k127_3431509_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.448e-212 664.0
TLS3_k127_3431509_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000004704 220.0
TLS3_k127_3442596_0 DNA replication and repair protein RecF - - - 0.0 1392.0
TLS3_k127_3442596_1 Recombination factor protein RarA K07478 - - 1.932e-232 727.0
TLS3_k127_3442596_10 Cell division protein ftsk K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001876 265.0
TLS3_k127_3442596_11 EcsC protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003881 270.0
TLS3_k127_3442596_12 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000000000000002941 204.0
TLS3_k127_3442596_13 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000005163 205.0
TLS3_k127_3442596_14 Aspartyl asparaginyl beta-hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000007821 213.0
TLS3_k127_3442596_15 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000008027 218.0
TLS3_k127_3442596_16 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000001242 203.0
TLS3_k127_3442596_17 - - - - 0.000000000000000000000000000000000000000000000000006947 192.0
TLS3_k127_3442596_18 thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.00000000000000000000000000000000000007524 152.0
TLS3_k127_3442596_2 - - - - 2.989e-213 673.0
TLS3_k127_3442596_3 Penicillin acylase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 502.0
TLS3_k127_3442596_4 Pseudouridylate K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 377.0
TLS3_k127_3442596_5 Uncharacterized protein conserved in bacteria C-term(DUF2220) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 370.0
TLS3_k127_3442596_6 Linear gramicidin synthase subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 356.0
TLS3_k127_3442596_7 Domain of unknown function (DUF4194) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 328.0
TLS3_k127_3442596_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001706 283.0
TLS3_k127_3442596_9 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003883 280.0
TLS3_k127_3453026_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1365.0
TLS3_k127_3453026_1 Multidrug MFS transporter - - - 4.696e-299 939.0
TLS3_k127_3453026_10 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 327.0
TLS3_k127_3453026_11 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 322.0
TLS3_k127_3453026_12 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000002533 269.0
TLS3_k127_3453026_13 protein conserved in bacteria K15539 - - 0.00000000000000000000000000000000000000000000000000000000000000000002921 242.0
TLS3_k127_3453026_14 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000001017 228.0
TLS3_k127_3453026_15 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000004314 221.0
TLS3_k127_3453026_16 MASE1 - - - 0.000000000000000000000000000000000000000000000000000000000004184 227.0
TLS3_k127_3453026_17 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000000000000004274 190.0
TLS3_k127_3453026_18 - K08992 - - 0.00000000001879 70.0
TLS3_k127_3453026_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00632 - 2.3.1.16 2.641e-238 740.0
TLS3_k127_3453026_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.674e-236 739.0
TLS3_k127_3453026_4 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 8.493e-217 680.0
TLS3_k127_3453026_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 4.573e-209 657.0
TLS3_k127_3453026_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 571.0
TLS3_k127_3453026_7 molybdopterin biosynthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 527.0
TLS3_k127_3453026_8 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 513.0
TLS3_k127_3453026_9 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 478.0
TLS3_k127_3480657_0 COG3321 Polyketide synthase modules and related proteins - - - 0.0 2290.0
TLS3_k127_3480657_1 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.0 2054.0
TLS3_k127_3480657_2 Transposase and inactivated derivatives K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 523.0
TLS3_k127_3480657_3 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000003343 102.0
TLS3_k127_3480657_4 Polyketide synthase modules K15328 - - 0.000000003447 65.0
TLS3_k127_3480657_5 Malonyl CoA-acyl carrier protein transacylase K15329 - - 0.00000001026 57.0
TLS3_k127_3491625_0 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor - - - 0.0 1050.0
TLS3_k127_3491625_1 Sodium:sulfate symporter transmembrane region - - - 4.494e-297 921.0
TLS3_k127_3491625_10 - - - - 0.0000000000000000000000000000000000000000000000000003108 190.0
TLS3_k127_3491625_11 peptidoglycan-binding protein, lysm - - - 0.00000000000000000000000000000005125 139.0
TLS3_k127_3491625_12 - - - - 0.00000000000000000000000001663 113.0
TLS3_k127_3491625_13 Tetratricopeptide repeat - - - 0.0003092 49.0
TLS3_k127_3491625_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 4.509e-263 812.0
TLS3_k127_3491625_3 Sodium ABC transporter permease K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 475.0
TLS3_k127_3491625_4 abc transporter atp-binding protein K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 409.0
TLS3_k127_3491625_5 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 415.0
TLS3_k127_3491625_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 388.0
TLS3_k127_3491625_7 Belongs to the UPF0149 family K07039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 363.0
TLS3_k127_3491625_8 Alpha-lytic protease prodomain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 334.0
TLS3_k127_3491625_9 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000249 213.0
TLS3_k127_3493056_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 4.471e-246 769.0
TLS3_k127_3493056_1 Methylmalonate-semialdehyde dehydrogenase acylating K00140 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0004491,GO:0005488,GO:0006082,GO:0006139,GO:0006206,GO:0006520,GO:0006573,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009081,GO:0009112,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0017076,GO:0018478,GO:0019752,GO:0019859,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033218,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901567,GO:1901605,GO:1901681 1.2.1.18,1.2.1.27 0.0000000000000000000005017 94.0
TLS3_k127_3495797_0 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 2.883e-244 773.0
TLS3_k127_3495797_1 Acetyl-CoA dehydrogenase C-terminal like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 459.0
TLS3_k127_3495797_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000002308 160.0
TLS3_k127_3496405_0 Histidine kinase - - - 5.07e-291 914.0
TLS3_k127_3496405_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.632e-198 620.0
TLS3_k127_3496405_10 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 294.0
TLS3_k127_3496405_11 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001431 277.0
TLS3_k127_3496405_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004822 255.0
TLS3_k127_3496405_13 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003086 250.0
TLS3_k127_3496405_14 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000000000006898 235.0
TLS3_k127_3496405_15 Iron-sulfur cluster insertion protein ErpA K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564 - 0.000000000000000000000000000000000000000000000000000001797 194.0
TLS3_k127_3496405_16 Phasin protein - - - 0.00000000000000000000000000000000000000000000000001122 184.0
TLS3_k127_3496405_17 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000001239 163.0
TLS3_k127_3496405_2 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 614.0
TLS3_k127_3496405_20 bacterioferritin K02192 - - 0.000000000000009142 80.0
TLS3_k127_3496405_21 bacterial-type flagellum organization K02279,K02386 - - 0.0009458 48.0
TLS3_k127_3496405_3 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 496.0
TLS3_k127_3496405_4 nadh pyrophosphatase K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 370.0
TLS3_k127_3496405_5 Membrane protein required for beta-lactamase induction K03807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 361.0
TLS3_k127_3496405_6 Protein of unknown function (DUF3228) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 332.0
TLS3_k127_3496405_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 335.0
TLS3_k127_3496405_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 321.0
TLS3_k127_3496405_9 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 317.0
TLS3_k127_349861_0 sh3 domain protein - - - 9.146e-232 736.0
TLS3_k127_349861_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 6.266e-210 664.0
TLS3_k127_349861_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009441 564.0
TLS3_k127_349861_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 508.0
TLS3_k127_349861_4 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 497.0
TLS3_k127_349861_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 458.0
TLS3_k127_349861_6 secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 364.0
TLS3_k127_349861_7 - - - - 0.0000000000000000000000000000000000000000001131 165.0
TLS3_k127_349861_8 - - - - 0.00000000000000000000000000000000003532 146.0
TLS3_k127_349861_9 - - - - 0.0000000000000000000002508 100.0
TLS3_k127_3537026_0 glutamate--cysteine ligase K01919 - 6.3.2.2 9.268e-264 818.0
TLS3_k127_3537026_1 multicopper - - - 1.677e-250 778.0
TLS3_k127_3537026_10 Belongs to the peptidase S8 family K14647 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001452 265.0
TLS3_k127_3537026_11 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000000000000000000000000001641 247.0
TLS3_k127_3537026_12 Putative prokaryotic signal transducing protein - - - 0.000000000000000000000000000000000000000000000000005571 191.0
TLS3_k127_3537026_13 Thiol disulfide Interchange Protein K03673 - - 0.00000000000000000000000000000000000000000000003932 177.0
TLS3_k127_3537026_2 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 7.962e-249 776.0
TLS3_k127_3537026_3 Binding-protein-dependent transport system inner membrane component K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 509.0
TLS3_k127_3537026_4 endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 407.0
TLS3_k127_3537026_5 Copper resistance K07233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 362.0
TLS3_k127_3537026_6 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 335.0
TLS3_k127_3537026_7 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 328.0
TLS3_k127_3537026_8 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 314.0
TLS3_k127_3537026_9 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 327.0
TLS3_k127_3542400_0 glutamate dehydrogenase K15371 - 1.4.1.2 0.0 2487.0
TLS3_k127_3542400_1 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0 1546.0
TLS3_k127_3542400_10 lysozyme K01185 - 3.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 350.0
TLS3_k127_3542400_11 peptidylprolyl K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 349.0
TLS3_k127_3542400_12 Domain of unknown function (DUF4785) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 340.0
TLS3_k127_3542400_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 328.0
TLS3_k127_3542400_14 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 292.0
TLS3_k127_3542400_15 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006478 277.0
TLS3_k127_3542400_16 Nucleoprotein polynucleotide-associated enzyme K09912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001479 272.0
TLS3_k127_3542400_17 peptidylprolyl K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000006152 273.0
TLS3_k127_3542400_18 peptidylprolyl K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000003453 239.0
TLS3_k127_3542400_19 GntR family transcriptional regulator K07979 - - 0.0000000000000000000000000000000000000000000000000000000000002085 214.0
TLS3_k127_3542400_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 4.516e-245 763.0
TLS3_k127_3542400_20 - - - - 0.0000000000000000000000000000007671 126.0
TLS3_k127_3542400_21 Belongs to the SlyX family K03745 - - 0.000000000000000000001561 95.0
TLS3_k127_3542400_22 abc transporter atp-binding protein K01990 - - 0.00000000000001793 82.0
TLS3_k127_3542400_3 acyl-CoA dehydrogenase - - - 2.567e-232 745.0
TLS3_k127_3542400_4 Protein of unknown function (DUF4080) - - - 3.67e-208 659.0
TLS3_k127_3542400_5 Methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008348 591.0
TLS3_k127_3542400_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 486.0
TLS3_k127_3542400_7 ArsR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 511.0
TLS3_k127_3542400_8 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 469.0
TLS3_k127_3542400_9 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 405.0
TLS3_k127_3580138_0 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 615.0
TLS3_k127_3580138_1 Pfam:NRPS - - - 0.0000000000000000000445 93.0
TLS3_k127_361166_0 abc transporter atp-binding protein - - - 0.0 1020.0
TLS3_k127_361166_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.502e-243 757.0
TLS3_k127_361166_2 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 448.0
TLS3_k127_361166_3 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007179 280.0
TLS3_k127_361166_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000003209 156.0
TLS3_k127_361166_5 Erythromycin esterase - - - 0.000000000000000000000000000007011 123.0
TLS3_k127_361166_6 integral membrane protein - - - 0.0000000000000000007906 102.0
TLS3_k127_3617898_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1542.0
TLS3_k127_3617898_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 3.655e-245 767.0
TLS3_k127_3617898_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 458.0
TLS3_k127_3617898_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008236 271.0
TLS3_k127_3617898_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000008821 157.0
TLS3_k127_3617898_5 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000000000001487 154.0
TLS3_k127_3634061_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1402.0
TLS3_k127_3634061_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.405e-317 985.0
TLS3_k127_3634061_10 Protein of unknown function (DUF1275) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 327.0
TLS3_k127_3634061_11 Belongs to the Smg family K03747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000844 279.0
TLS3_k127_3634061_12 membrane protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002569 277.0
TLS3_k127_3634061_13 peptidoglycan-binding protein, lysm - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000048 261.0
TLS3_k127_3634061_14 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000002042 217.0
TLS3_k127_3634061_15 - - - - 0.000000000000000000000000000000000000000000000000000887 194.0
TLS3_k127_3634061_16 - - - - 0.0000000000000000000000000000000001035 140.0
TLS3_k127_3634061_17 Tfp pilus assembly protein, major pilin PilA K02650 - - 0.0000000000000000000000000000002668 134.0
TLS3_k127_3634061_18 Tfp pilus assembly protein, major pilin PilA K02650 - - 0.00000000000000004282 89.0
TLS3_k127_3634061_2 Histidine kinase K07646 - 2.7.13.3 6.184e-302 940.0
TLS3_k127_3634061_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 3.504e-264 824.0
TLS3_k127_3634061_4 Multicopper oxidase K00423 - 1.10.3.3 1.456e-231 737.0
TLS3_k127_3634061_5 glycoside hydrolase family 16 - - - 9.974e-198 632.0
TLS3_k127_3634061_6 Lytic polysaccharide mono-oxygenase, cellulose-degrading K03933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 526.0
TLS3_k127_3634061_7 DNA processing protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 464.0
TLS3_k127_3634061_8 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 402.0
TLS3_k127_3634061_9 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 366.0
TLS3_k127_3659573_0 Phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 522.0
TLS3_k127_3659573_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000172 254.0
TLS3_k127_3659573_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000001385 99.0
TLS3_k127_3659573_3 secretion protein K01993 - - 0.00000000001355 68.0
TLS3_k127_3683927_0 amino acid K03294 - - 1.697e-232 731.0
TLS3_k127_3683927_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 446.0
TLS3_k127_3683927_10 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.00000000000000000000000000004098 121.0
TLS3_k127_3683927_11 - - - - 0.00000000000000000006987 106.0
TLS3_k127_3683927_12 - - - - 0.000000000000000004722 94.0
TLS3_k127_3683927_13 - - - - 0.0000000000003586 80.0
TLS3_k127_3683927_2 Elongation factor P K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 355.0
TLS3_k127_3683927_3 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 350.0
TLS3_k127_3683927_4 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 333.0
TLS3_k127_3683927_5 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 294.0
TLS3_k127_3683927_6 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000569 259.0
TLS3_k127_3683927_7 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001454 248.0
TLS3_k127_3683927_8 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000004297 242.0
TLS3_k127_3683927_9 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 0.00000000000000000000000000000000000000000000000000006318 188.0
TLS3_k127_3687532_0 Prokaryotic glutathione synthetase, ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1557.0
TLS3_k127_3687532_1 Mur ligase family, glutamate ligase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 599.0
TLS3_k127_3687532_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 536.0
TLS3_k127_3687532_3 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008270,GO:0008798,GO:0016787,GO:0019538,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 534.0
TLS3_k127_3687532_4 Peptidase family S51 K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 424.0
TLS3_k127_3687532_5 In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 353.0
TLS3_k127_3687532_6 Peptidase family M28 K19702 - 3.4.11.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 317.0
TLS3_k127_3687532_7 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000003242 182.0
TLS3_k127_3687532_8 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000004279 198.0
TLS3_k127_3687532_9 Domain of unknown function (DUF4468) with TBP-like fold - - - 0.000000000000000000000000000000000001225 146.0
TLS3_k127_3724800_0 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 435.0
TLS3_k127_3724800_1 Protein of unknown function (DUF3540) - - - 0.00000000000000000000000000000000000009326 154.0
TLS3_k127_3724800_2 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000001 124.0
TLS3_k127_3724800_3 Domain of unknown function (DUF4150) - - - 0.000000000000000000139 90.0
TLS3_k127_3740815_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1658.0
TLS3_k127_3740815_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1489.0
TLS3_k127_3740815_10 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 372.0
TLS3_k127_3740815_11 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K07400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 344.0
TLS3_k127_3740815_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 354.0
TLS3_k127_3740815_13 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000003035 237.0
TLS3_k127_3740815_14 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000000000000000000105 206.0
TLS3_k127_3740815_15 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000000000000000001443 201.0
TLS3_k127_3740815_17 cytochrome - - - 0.00000000000000000000000000000000000003735 149.0
TLS3_k127_3740815_18 - - - - 0.000000000000000000000000000000000003111 143.0
TLS3_k127_3740815_19 - - - - 0.000000000000000000000000000000003191 139.0
TLS3_k127_3740815_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1011.0
TLS3_k127_3740815_20 Cytochrome c - - - 0.0000000000000000000000000000006303 128.0
TLS3_k127_3740815_22 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000000001094 83.0
TLS3_k127_3740815_23 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000468 64.0
TLS3_k127_3740815_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.386e-241 755.0
TLS3_k127_3740815_4 trab family - - - 1.021e-202 638.0
TLS3_k127_3740815_5 Acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 572.0
TLS3_k127_3740815_6 Belongs to the agmatine deiminase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 573.0
TLS3_k127_3740815_7 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 526.0
TLS3_k127_3740815_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 485.0
TLS3_k127_3740815_9 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 396.0
TLS3_k127_3796084_0 Histidine kinase - - - 6.384e-224 718.0
TLS3_k127_3837764_0 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 1.125e-234 742.0
TLS3_k127_3837764_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 2.837e-200 638.0
TLS3_k127_3837764_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000008958 264.0
TLS3_k127_3837764_11 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000154 140.0
TLS3_k127_3837764_12 - - - - 0.0000000000000000000000000000002849 130.0
TLS3_k127_3837764_13 Glutaredoxin - - - 0.000000000000423 75.0
TLS3_k127_3837764_14 abc transporter atp-binding protein K09697 - 3.6.3.7 0.0000000179 59.0
TLS3_k127_3837764_2 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 533.0
TLS3_k127_3837764_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 517.0
TLS3_k127_3837764_4 Preprotein translocase subunit TatD K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 470.0
TLS3_k127_3837764_5 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 468.0
TLS3_k127_3837764_6 phenol hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 427.0
TLS3_k127_3837764_7 Protein of unknown function (DUF2167) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 360.0
TLS3_k127_3837764_8 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 314.0
TLS3_k127_3837764_9 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001418 269.0
TLS3_k127_3847736_0 Prolyl oligopeptidase K01322 - 3.4.21.26 1.407e-315 978.0
TLS3_k127_3847736_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001097 270.0
TLS3_k127_3847736_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000008114 234.0
TLS3_k127_3847736_3 - - - - 0.0000001308 59.0
TLS3_k127_3902436_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 397.0
TLS3_k127_3902436_1 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 286.0
TLS3_k127_3902436_2 Killing trait - - - 0.000000000000000000000000000000000000000000006593 179.0
TLS3_k127_3902632_0 Oxidoreductase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 580.0
TLS3_k127_3902632_1 membrane protein terc K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 423.0
TLS3_k127_3965765_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 2.262e-247 766.0
TLS3_k127_3965765_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 7.126e-231 741.0
TLS3_k127_3965765_10 stringent starvation protein b K03600 - - 0.00000000000000000000000000000000000000000000000001333 186.0
TLS3_k127_3965765_11 Protein of unknown function (DUF3293) - - - 0.0000000000000000000000000000000000000000000000004989 182.0
TLS3_k127_3965765_12 Protein of unknown function (DUF3301) - - - 0.0000000000000000000000000000000000001441 144.0
TLS3_k127_3965765_13 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000004902 80.0
TLS3_k127_3965765_2 aminotransferase K14287 - 2.6.1.88 4.039e-209 656.0
TLS3_k127_3965765_3 geranylgeranyl reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 505.0
TLS3_k127_3965765_4 carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 471.0
TLS3_k127_3965765_5 stringent starvation protein A K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 387.0
TLS3_k127_3965765_6 cytochrome K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 375.0
TLS3_k127_3965765_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 363.0
TLS3_k127_3965765_8 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 370.0
TLS3_k127_3965765_9 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008269 251.0
TLS3_k127_3969295_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 516.0
TLS3_k127_3969295_1 Polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 442.0
TLS3_k127_3969295_2 regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 386.0
TLS3_k127_3969295_3 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 344.0
TLS3_k127_3969295_4 acetyltransferase K06977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 329.0
TLS3_k127_3969295_5 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000003312 152.0
TLS3_k127_3969295_6 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000002628 126.0
TLS3_k127_40045_0 Belongs to the aldehyde dehydrogenase family K00130,K00151,K10217 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0008802,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 2.884e-255 792.0
TLS3_k127_40045_1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates K01141 - 3.1.11.1 1.898e-221 694.0
TLS3_k127_40045_2 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 8.291e-214 678.0
TLS3_k127_40045_3 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase K03392 - 4.1.1.45 1.23e-212 665.0
TLS3_k127_40045_4 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 3.575e-210 662.0
TLS3_k127_40045_5 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 380.0
TLS3_k127_40045_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 352.0
TLS3_k127_40045_7 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 316.0
TLS3_k127_40045_8 translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.0000000000000000000000000000000000000000000000000000000000000001039 235.0
TLS3_k127_4023112_0 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 341.0
TLS3_k127_4023112_1 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 327.0
TLS3_k127_4023112_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000003927 114.0
TLS3_k127_4023112_3 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000007102 77.0
TLS3_k127_4053409_0 Halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 426.0
TLS3_k127_4053409_1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 376.0
TLS3_k127_4053409_2 Phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000001616 197.0
TLS3_k127_4053409_3 membrane - - - 0.000000006463 58.0
TLS3_k127_4059684_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1478.0
TLS3_k127_4059684_1 Dienelactone hydrolase family - - - 0.0 1032.0
TLS3_k127_4059684_10 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000504 221.0
TLS3_k127_4059684_11 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000002584 194.0
TLS3_k127_4059684_12 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000009565 130.0
TLS3_k127_4059684_13 TIGRFAM Addiction module toxin, RelE StbE K19092 - - 0.000000000000000000000000008038 112.0
TLS3_k127_4059684_14 Bacteriophage CI repressor helix-turn-helix domain - - - 0.0000000000000000000007582 104.0
TLS3_k127_4059684_15 SEC-C motif - - - 0.000000000000000001257 87.0
TLS3_k127_4059684_16 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000001805 92.0
TLS3_k127_4059684_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.571e-294 911.0
TLS3_k127_4059684_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 607.0
TLS3_k127_4059684_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 394.0
TLS3_k127_4059684_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 352.0
TLS3_k127_4059684_6 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 354.0
TLS3_k127_4059684_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 308.0
TLS3_k127_4059684_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001668 233.0
TLS3_k127_4059684_9 Glutamyl-tRNA amidotransferase K09117 - - 0.00000000000000000000000000000000000000000000000000000000000009675 218.0
TLS3_k127_4131347_0 Ami_2 - - - 0.0 1281.0
TLS3_k127_4131347_1 - - - - 0.000000000000000007915 85.0
TLS3_k127_4151658_0 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 511.0
TLS3_k127_4151658_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 359.0
TLS3_k127_4151658_2 deoxyribonuclease I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 338.0
TLS3_k127_4175315_0 Bacterial periplasmic substrate-binding proteins K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008397 524.0
TLS3_k127_4175315_1 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 502.0
TLS3_k127_4175315_2 acid transport system permease K09970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 387.0
TLS3_k127_4175315_3 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.000000000000000000000000000000000000000000000003595 173.0
TLS3_k127_4208592_0 Potassium transporter TrkA - - - 3.853e-304 942.0
TLS3_k127_4208592_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 4.545e-283 876.0
TLS3_k127_4208592_10 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000006698 161.0
TLS3_k127_4208592_11 - - - - 0.00000000000000000000000000002611 124.0
TLS3_k127_4208592_12 - - - - 0.00000000000000000000000002374 114.0
TLS3_k127_4208592_13 Thiamine biosynthesis protein K03154 - - 0.0000000000000000000007888 96.0
TLS3_k127_4208592_14 multivesicular body membrane disassembly - - - 0.0000000000000000003551 101.0
TLS3_k127_4208592_15 - - - - 0.000000000000000002506 91.0
TLS3_k127_4208592_2 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 541.0
TLS3_k127_4208592_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 479.0
TLS3_k127_4208592_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 430.0
TLS3_k127_4208592_5 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 405.0
TLS3_k127_4208592_6 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 395.0
TLS3_k127_4208592_7 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 384.0
TLS3_k127_4208592_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000002656 231.0
TLS3_k127_4208592_9 multivesicular body membrane disassembly - - - 0.0000000000000000000000000000000000000000000000000000000000001255 230.0
TLS3_k127_429166_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 413.0
TLS3_k127_429166_1 HipA N-terminal domain K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 386.0
TLS3_k127_4318522_0 Zn_pept - - - 2.977e-319 994.0
TLS3_k127_4318522_1 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 8.225e-276 863.0
TLS3_k127_4318522_10 Helix-turn-helix type 11 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 297.0
TLS3_k127_4318522_11 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000000000000000004406 223.0
TLS3_k127_4318522_12 - - - - 0.000000000000000000000000000000000000000000000000000000183 203.0
TLS3_k127_4318522_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000003682 153.0
TLS3_k127_4318522_14 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000002587 147.0
TLS3_k127_4318522_15 RNA-binding protein K14761 - - 0.0000000000000000000000000006725 114.0
TLS3_k127_4318522_2 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 6.859e-222 699.0
TLS3_k127_4318522_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 2.845e-204 653.0
TLS3_k127_4318522_4 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 595.0
TLS3_k127_4318522_5 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 430.0
TLS3_k127_4318522_6 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 396.0
TLS3_k127_4318522_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 342.0
TLS3_k127_4318522_8 histidine kinase A domain protein K07679 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 350.0
TLS3_k127_4318522_9 Protein of unknown function (DUF2589) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 321.0
TLS3_k127_4329760_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 421.0
TLS3_k127_4329760_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 371.0
TLS3_k127_4329760_2 - - - - 0.000000000000000000000000000000000000000000000000002137 194.0
TLS3_k127_4329760_3 - - - - 0.00000000000000000000000000000000000000000001012 174.0
TLS3_k127_4329760_4 Belongs to the ompA family - - - 0.0000000000000000000001997 113.0
TLS3_k127_4331994_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 524.0
TLS3_k127_4331994_1 antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 391.0
TLS3_k127_4331994_2 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 358.0
TLS3_k127_4331994_3 - - - - 0.000000000000000000000000000000000000000000000000000703 188.0
TLS3_k127_4375708_0 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) K01083 - 3.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 403.0
TLS3_k127_4375708_1 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001658 274.0
TLS3_k127_4408243_0 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 577.0
TLS3_k127_4408243_1 Nacht domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 532.0
TLS3_k127_4408243_2 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 318.0
TLS3_k127_4408243_3 - - - - 0.0000000000000000000000000000000000002123 146.0
TLS3_k127_4437949_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1156.0
TLS3_k127_4437949_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.195e-276 853.0
TLS3_k127_4437949_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 473.0
TLS3_k127_4437949_3 Chaperone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001334 270.0
TLS3_k127_4437949_4 - - - - 0.00000000000000000000000000000000000000000000000000000000009718 211.0
TLS3_k127_4437949_5 - - - - 0.00000000000000000000000000000000000000000006037 168.0
TLS3_k127_4437949_6 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000003777 146.0
TLS3_k127_4437949_7 - - - - 0.000000000000000000000000000000000001967 152.0
TLS3_k127_4455511_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 532.0
TLS3_k127_4455511_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 331.0
TLS3_k127_4455511_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 299.0
TLS3_k127_4480565_0 Protein of unknown function (DUF979) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 449.0
TLS3_k127_4480565_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 428.0
TLS3_k127_4480565_2 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 366.0
TLS3_k127_4480565_3 Protein of unknown function (DUF969) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 344.0
TLS3_k127_4480565_4 Allophanate hydrolase subunit 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 349.0
TLS3_k127_4480565_5 LamB/YcsF family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 316.0
TLS3_k127_4480565_6 Allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001812 280.0
TLS3_k127_4480565_7 Pyroglutamyl peptidase K01304 - 3.4.19.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005778 263.0
TLS3_k127_4480565_8 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000003197 246.0
TLS3_k127_4480565_9 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000001485 217.0
TLS3_k127_4555035_0 Molecular chaperone. Has ATPase activity K04079 - - 2.058e-273 857.0
TLS3_k127_4555035_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 405.0
TLS3_k127_4555035_10 Domain of unknown function (DUF4157) - - - 0.00000000000001253 83.0
TLS3_k127_4555035_11 Beta-lactamase - - - 0.0000000000006563 70.0
TLS3_k127_4555035_12 IstB-like ATP binding protein - - - 0.00000000001155 73.0
TLS3_k127_4555035_13 - - - - 0.000000000125 68.0
TLS3_k127_4555035_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000004229 262.0
TLS3_k127_4555035_3 pilus assembly protein PilW - - - 0.000000000000000000000000000000000000000000000000001847 196.0
TLS3_k127_4555035_4 Uncharacterized protein conserved in bacteria C-term(DUF2220) - - - 0.000000000000000000000000000000000000000001588 162.0
TLS3_k127_4555035_5 - - - - 0.00000000000000000000000000000000000003015 166.0
TLS3_k127_4555035_6 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000000000000000000006458 143.0
TLS3_k127_4555035_7 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000007129 104.0
TLS3_k127_4555035_8 nuclear chromosome segregation - - - 0.000000000000000008865 93.0
TLS3_k127_4555035_9 Transcriptional regulatory protein, C terminal - - - 0.000000000000003747 77.0
TLS3_k127_4562395_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 3.391e-196 615.0
TLS3_k127_4562395_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 507.0
TLS3_k127_4562395_2 COG4240 Predicted kinase K15918 - 2.7.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 334.0
TLS3_k127_4562395_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 302.0
TLS3_k127_4562395_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000005479 221.0
TLS3_k127_4562395_5 - - - - 0.0000000000000000000000000000000000004086 141.0
TLS3_k127_4562395_6 Dodecin K09165 - - 0.00000000000000000000000000003117 118.0
TLS3_k127_4562395_7 - - - - 0.00006285 51.0
TLS3_k127_4573288_0 Halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 485.0
TLS3_k127_4573288_1 Dolichyl-phosphate mannose synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 394.0
TLS3_k127_4573288_2 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000114 56.0
TLS3_k127_4575418_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1393.0
TLS3_k127_4575418_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1277.0
TLS3_k127_4575418_10 methyltransferase - - - 0.00000000001438 77.0
TLS3_k127_4575418_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 0.0 1227.0
TLS3_k127_4575418_3 TonB dependent receptor - - - 0.0 1179.0
TLS3_k127_4575418_4 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 275.0
TLS3_k127_4575418_5 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003257 270.0
TLS3_k127_4575418_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 254.0
TLS3_k127_4575418_7 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001011 212.0
TLS3_k127_4575418_8 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000001743 225.0
TLS3_k127_4575418_9 Belongs to the HSP15 family K04762 - - 0.0000000000000000000000000000000000000000000000000008563 189.0
TLS3_k127_4579398_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1691.0
TLS3_k127_4579398_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 4.161e-257 805.0
TLS3_k127_4579398_10 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 401.0
TLS3_k127_4579398_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 376.0
TLS3_k127_4579398_12 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 371.0
TLS3_k127_4579398_13 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 295.0
TLS3_k127_4579398_14 Amino-transferase class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 304.0
TLS3_k127_4579398_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001012 289.0
TLS3_k127_4579398_16 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000878 259.0
TLS3_k127_4579398_17 ACR protein K07040 - - 0.000000000000000000000000000000000000000000000000000000000000003421 230.0
TLS3_k127_4579398_18 Pilus assembly protein PilZ K02676 - - 0.000000000000000000000000000000000000000000000000000003239 199.0
TLS3_k127_4579398_19 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000002424 186.0
TLS3_k127_4579398_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.314e-224 703.0
TLS3_k127_4579398_20 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000002104 166.0
TLS3_k127_4579398_21 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000009026 147.0
TLS3_k127_4579398_22 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000005546 136.0
TLS3_k127_4579398_23 - - - - 0.000000000000000000000000001303 118.0
TLS3_k127_4579398_24 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000001806 114.0
TLS3_k127_4579398_26 - - - - 0.00000000008326 66.0
TLS3_k127_4579398_28 pectinesterase activity K01224 - 3.2.1.89 0.0002737 51.0
TLS3_k127_4579398_3 component I K01657 - 4.1.3.27 7.334e-215 679.0
TLS3_k127_4579398_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 595.0
TLS3_k127_4579398_5 Major facilitator superfamily K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 539.0
TLS3_k127_4579398_6 Amino acid permease K03294,K03759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 515.0
TLS3_k127_4579398_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 482.0
TLS3_k127_4579398_8 the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 462.0
TLS3_k127_4579398_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 453.0
TLS3_k127_4615512_0 Peptidase family S41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 392.0
TLS3_k127_4615512_1 Transcriptional regulator K07727 - - 0.00000000001203 65.0
TLS3_k127_4622158_0 NADH flavin oxidoreductase NADH oxidase K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 570.0
TLS3_k127_4622158_1 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000015 165.0
TLS3_k127_4622158_2 - - - - 0.000000000000000000000000000000000001325 160.0
TLS3_k127_4622158_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000004629 86.0
TLS3_k127_4643499_0 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000239 257.0
TLS3_k127_4643499_1 Pectate lyase K01728 GO:0005575,GO:0005576 4.2.2.2 0.000000000000000000000000000000000000000000000000005482 188.0
TLS3_k127_4643499_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000001241 60.0
TLS3_k127_4655362_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 5.852e-240 743.0
TLS3_k127_4655362_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 5.434e-217 678.0
TLS3_k127_4679660_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 588.0
TLS3_k127_4679660_1 Methyltransferase K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 402.0
TLS3_k127_4762738_0 Outer membrane receptor - - - 0.0 1050.0
TLS3_k127_4762738_1 COG0457 FOG TPR repeat - - - 2.363e-295 922.0
TLS3_k127_4762738_10 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 329.0
TLS3_k127_4762738_11 Uncharacterised protein family (UPF0093) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007335 234.0
TLS3_k127_4762738_12 PadR family transcriptional regulator K10947 - - 0.000000000000000000000000000000000000000000000000001299 186.0
TLS3_k127_4762738_13 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000006329 117.0
TLS3_k127_4762738_14 TfoX N-terminal domain K07343 - - 0.0000000000000000972 81.0
TLS3_k127_4762738_15 Beta-lactamase K17836 - 3.5.2.6 0.0000000000001029 83.0
TLS3_k127_4762738_16 TfoX N-terminal domain - - - 0.0000000002233 61.0
TLS3_k127_4762738_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 3.321e-254 820.0
TLS3_k127_4762738_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 6.081e-234 731.0
TLS3_k127_4762738_4 Serine Threonine protein K08884,K12132 - 2.7.11.1 5.911e-225 708.0
TLS3_k127_4762738_5 de-polymerase K05973 - 3.1.1.75 1.934e-220 694.0
TLS3_k127_4762738_6 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 437.0
TLS3_k127_4762738_7 Putative sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 421.0
TLS3_k127_4762738_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 350.0
TLS3_k127_4762738_9 Extradiol ring-cleavage dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 345.0
TLS3_k127_4780389_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1014.0
TLS3_k127_4780389_1 alpha-glucosidase K01187 - 3.2.1.20 3.38e-316 987.0
TLS3_k127_4804994_0 Belongs to the pseudouridine synthase RsuA family K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 297.0
TLS3_k127_4804994_1 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000002342 186.0
TLS3_k127_4804994_2 Helicase K03579 - 3.6.4.13 0.0000000000000000000003463 95.0
TLS3_k127_4841818_0 gtp-binding protein K06207 - - 0.0 1127.0
TLS3_k127_4841818_1 2,4-dienoyl-coa reductase K00219 - 1.3.1.34 0.0 1086.0
TLS3_k127_4841818_10 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 528.0
TLS3_k127_4841818_11 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 407.0
TLS3_k127_4841818_12 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 405.0
TLS3_k127_4841818_13 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 342.0
TLS3_k127_4841818_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 311.0
TLS3_k127_4841818_15 Response regulator of the LytR AlgR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 311.0
TLS3_k127_4841818_16 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 284.0
TLS3_k127_4841818_17 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 284.0
TLS3_k127_4841818_18 Cell Wall - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001289 269.0
TLS3_k127_4841818_19 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000000000000000000000003816 223.0
TLS3_k127_4841818_2 2-methylcitrate dehydratase K01720 - 4.2.1.79 4.845e-262 812.0
TLS3_k127_4841818_20 - - - - 0.00000000000000000000000000000000000000000000000000001062 206.0
TLS3_k127_4841818_21 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000001069 177.0
TLS3_k127_4841818_22 membrane - - - 0.000000000000000000000000000000000001213 147.0
TLS3_k127_4841818_23 Histidine kinase - - - 0.000000000000000000000000000000000009408 151.0
TLS3_k127_4841818_24 Ion channel - - - 0.0000000000000000000000000000000006207 136.0
TLS3_k127_4841818_25 - - - - 0.00000000000000000000000002542 123.0
TLS3_k127_4841818_26 - - - - 0.00000000000000000005508 98.0
TLS3_k127_4841818_28 membrane - - - 0.00000004844 62.0
TLS3_k127_4841818_3 aminotransferase K00812 - 2.6.1.1 3.534e-231 726.0
TLS3_k127_4841818_4 also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity K01659 - 2.3.3.5 2.896e-227 724.0
TLS3_k127_4841818_5 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 9.327e-212 664.0
TLS3_k127_4841818_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 599.0
TLS3_k127_4841818_7 Helix-turn-helix domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 599.0
TLS3_k127_4841818_8 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 536.0
TLS3_k127_4841818_9 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 528.0
TLS3_k127_4866407_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1702.0
TLS3_k127_4866407_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 385.0
TLS3_k127_4866407_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000924 276.0
TLS3_k127_4866407_3 Diguanylate cyclase K08968 - 1.8.4.14 0.000000000000000000000000749 110.0
TLS3_k127_488264_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 8.169e-204 642.0
TLS3_k127_488264_1 Methyltransferase K00564 - 2.1.1.172 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 446.0
TLS3_k127_488264_2 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 404.0
TLS3_k127_488264_3 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 368.0
TLS3_k127_488264_4 Nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004249 258.0
TLS3_k127_488264_5 Protein of unknown function (DUF1415) K09941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004293 258.0
TLS3_k127_488264_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000001994 190.0
TLS3_k127_488264_7 serine threonine protein kinase - - - 0.000000000000000000000000000000000000005391 153.0
TLS3_k127_4896043_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1692.0
TLS3_k127_4896043_1 accessory protein K06959 - - 0.0 1251.0
TLS3_k127_4896043_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 452.0
TLS3_k127_4896043_3 Deoxycytidylate deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 382.0
TLS3_k127_4896043_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 324.0
TLS3_k127_4896043_5 SMART Prolyl 4-hydroxylase, alpha subunit K00472 - 1.14.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 313.0
TLS3_k127_4912995_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 459.0
TLS3_k127_4912995_1 DMSO reductase anchor subunit (DmsC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 308.0
TLS3_k127_4912995_2 4Fe-4S dicluster domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003066 245.0
TLS3_k127_4912995_3 Integrase, catalytic region - - - 0.00000000217 58.0
TLS3_k127_4922713_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K04103 - 4.1.1.74 9.643e-260 814.0
TLS3_k127_4922713_1 oxidoreductase activity - - - 0.0000000000000000003264 93.0
TLS3_k127_4981373_0 transcriptional regulator K22105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 314.0
TLS3_k127_4981373_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 310.0
TLS3_k127_4981373_2 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000005559 152.0
TLS3_k127_5003348_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 548.0
TLS3_k127_5003348_1 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 445.0
TLS3_k127_5003348_2 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 304.0
TLS3_k127_5003348_3 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001798 256.0
TLS3_k127_5003348_4 modulation protein K05808 - - 0.0000000000000000000000000000000000000000000001055 170.0
TLS3_k127_5003348_5 Predicted membrane protein (DUF2177) - - - 0.0008195 42.0
TLS3_k127_5044793_0 TonB dependent receptor K02014 - - 0.0 1026.0
TLS3_k127_5044793_1 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 2.017e-301 944.0
TLS3_k127_5044793_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 4.543e-229 720.0
TLS3_k127_5044793_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 417.0
TLS3_k127_5044793_4 Transporter - - - 0.0000000194 59.0
TLS3_k127_5056146_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.0 1037.0
TLS3_k127_5056146_1 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 0.0 1014.0
TLS3_k127_5056146_10 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 389.0
TLS3_k127_5056146_11 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 383.0
TLS3_k127_5056146_12 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 357.0
TLS3_k127_5056146_13 Belongs to the UPF0176 family K07146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 349.0
TLS3_k127_5056146_14 transport system permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 347.0
TLS3_k127_5056146_15 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 339.0
TLS3_k127_5056146_16 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 334.0
TLS3_k127_5056146_17 glutathione s-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 312.0
TLS3_k127_5056146_18 membrane protein (homolog of Drosophila rhomboid) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 294.0
TLS3_k127_5056146_19 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 296.0
TLS3_k127_5056146_2 TonB dependent receptor K02014 - - 1.259e-312 977.0
TLS3_k127_5056146_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003168 279.0
TLS3_k127_5056146_21 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000006817 268.0
TLS3_k127_5056146_22 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004668 260.0
TLS3_k127_5056146_23 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004676 260.0
TLS3_k127_5056146_24 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003984 255.0
TLS3_k127_5056146_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005334 252.0
TLS3_k127_5056146_26 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000002079 239.0
TLS3_k127_5056146_27 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000003317 151.0
TLS3_k127_5056146_28 Cold-shock protein K03704 - - 0.000000000000000000000000000000000003714 137.0
TLS3_k127_5056146_29 Cold-shock protein K03704 - - 0.000000000000000000000000000000000758 132.0
TLS3_k127_5056146_3 Carboxypeptidase - - - 1.247e-261 832.0
TLS3_k127_5056146_30 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000000008758 121.0
TLS3_k127_5056146_31 ISXO2-like transposase domain K07488 - - 0.0000000000000000000000000001003 118.0
TLS3_k127_5056146_32 - - - - 0.0000000000000000000005106 104.0
TLS3_k127_5056146_33 - - - - 0.000000000000000001915 93.0
TLS3_k127_5056146_34 Acetyltransferase (GNAT) domain - - - 0.000000000004672 77.0
TLS3_k127_5056146_4 Transporter K03305 - - 6.94e-261 814.0
TLS3_k127_5056146_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 3.398e-253 786.0
TLS3_k127_5056146_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 471.0
TLS3_k127_5056146_7 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 456.0
TLS3_k127_5056146_8 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 411.0
TLS3_k127_5056146_9 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 407.0
TLS3_k127_5113187_0 desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 598.0
TLS3_k127_5113187_1 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000001083 191.0
TLS3_k127_5182941_0 Lytic murein transglycosylase K08309 - - 2.263e-270 850.0
TLS3_k127_5182941_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 5.483e-199 627.0
TLS3_k127_5182941_10 ligase activity - - - 0.000000000000000000000000000000000000000002102 166.0
TLS3_k127_5182941_11 PFAM VanZ - - - 0.00000000000000000000000000000000000000002587 156.0
TLS3_k127_5182941_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.00000000000000000000000000000000000008229 149.0
TLS3_k127_5182941_13 Sulfotransferase - - - 0.0000000000001774 79.0
TLS3_k127_5182941_14 family 8 K00750 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0008466,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.186 0.0001129 53.0
TLS3_k127_5182941_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 557.0
TLS3_k127_5182941_3 IPT/TIG domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 527.0
TLS3_k127_5182941_4 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 392.0
TLS3_k127_5182941_5 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 368.0
TLS3_k127_5182941_7 WD domain, G-beta repeat K20332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005494 276.0
TLS3_k127_5182941_8 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000267 214.0
TLS3_k127_5182941_9 Bacterial PH domain - - - 0.00000000000000000000000000000000000000000000000000003781 194.0
TLS3_k127_5193004_0 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 439.0
TLS3_k127_5193004_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 433.0
TLS3_k127_5193004_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 345.0
TLS3_k127_5221281_0 Pyridoxal-phosphate dependent enzyme - - - 1.211e-201 635.0
TLS3_k127_5221281_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 603.0
TLS3_k127_5221281_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 454.0
TLS3_k127_5221281_3 Class II aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 296.0
TLS3_k127_5221281_4 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 291.0
TLS3_k127_5221281_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000001652 173.0
TLS3_k127_5221281_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000001932 166.0
TLS3_k127_5221281_7 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000007729 163.0
TLS3_k127_5221281_8 Protein of unknown function (DUF1272) - - - 0.00000000000000000000000000000000003801 135.0
TLS3_k127_5272838_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1471.0
TLS3_k127_5272838_1 chitinase K01183 - 3.2.1.14 0.0 1079.0
TLS3_k127_5272838_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 572.0
TLS3_k127_5272838_11 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 543.0
TLS3_k127_5272838_12 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 511.0
TLS3_k127_5272838_13 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 393.0
TLS3_k127_5272838_14 dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 394.0
TLS3_k127_5272838_15 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 391.0
TLS3_k127_5272838_16 Alpha beta K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 353.0
TLS3_k127_5272838_17 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 348.0
TLS3_k127_5272838_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 380.0
TLS3_k127_5272838_19 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 291.0
TLS3_k127_5272838_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0 1056.0
TLS3_k127_5272838_20 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001251 307.0
TLS3_k127_5272838_21 competence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002312 278.0
TLS3_k127_5272838_22 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007617 273.0
TLS3_k127_5272838_23 PFAM response regulator receiver K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007079 261.0
TLS3_k127_5272838_24 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001346 267.0
TLS3_k127_5272838_25 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002988 267.0
TLS3_k127_5272838_26 metallopeptidase activity K16922 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002093 263.0
TLS3_k127_5272838_27 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000001734 230.0
TLS3_k127_5272838_28 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000004077 237.0
TLS3_k127_5272838_29 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000001639 227.0
TLS3_k127_5272838_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.755e-285 901.0
TLS3_k127_5272838_30 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000004428 238.0
TLS3_k127_5272838_31 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000004567 192.0
TLS3_k127_5272838_32 response to abiotic stimulus - - - 0.00000000000000000000000000000000001071 142.0
TLS3_k127_5272838_33 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000001087 111.0
TLS3_k127_5272838_34 - - - - 0.000000000000000002941 90.0
TLS3_k127_5272838_35 - - - - 0.000000000000000003359 96.0
TLS3_k127_5272838_37 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0006278 53.0
TLS3_k127_5272838_4 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 2.159e-250 788.0
TLS3_k127_5272838_5 Nuclease K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 617.0
TLS3_k127_5272838_6 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 589.0
TLS3_k127_5272838_7 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 591.0
TLS3_k127_5272838_8 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 586.0
TLS3_k127_5272838_9 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 589.0
TLS3_k127_5284428_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 1.312e-291 915.0
TLS3_k127_5284428_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 2.442e-283 883.0
TLS3_k127_5284428_10 T5orf172 - - - 0.0000000000000000000000000000000000000000000000000000000000000003924 225.0
TLS3_k127_5284428_11 Biopolymer K03559 - - 0.00000000000000000000000000000000000000000000000000000000000008628 224.0
TLS3_k127_5284428_12 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000003622 211.0
TLS3_k127_5284428_13 sequence-specific DNA binding - - - 0.000000000000000000000002926 111.0
TLS3_k127_5284428_14 - - - - 0.00000000000000000000003849 111.0
TLS3_k127_5284428_16 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005979,GO:0006109,GO:0006139,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010675,GO:0010677,GO:0010906,GO:0010962,GO:0016070,GO:0016071,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032881,GO:0032885,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043255,GO:0043467,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045719,GO:0045912,GO:0045947,GO:0046483,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0062012,GO:0065007,GO:0070873,GO:0070874,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.0001023 50.0
TLS3_k127_5284428_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 4.797e-282 891.0
TLS3_k127_5284428_3 Nhl repeat - - - 4.662e-214 674.0
TLS3_k127_5284428_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 469.0
TLS3_k127_5284428_5 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 469.0
TLS3_k127_5284428_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 401.0
TLS3_k127_5284428_7 Biopolymer K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 357.0
TLS3_k127_5284428_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 343.0
TLS3_k127_5284428_9 Histidine kinase K07675,K14988,K20263 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 342.0
TLS3_k127_5288049_0 Major facilitator superfamily - - - 9.164e-194 615.0
TLS3_k127_5288049_1 LacI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 516.0
TLS3_k127_5288049_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000006678 104.0
TLS3_k127_5291454_0 Peptidase family M28 K05994 - 3.4.11.10 2.463e-213 688.0
TLS3_k127_5291454_1 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 583.0
TLS3_k127_5291454_10 Phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008125 280.0
TLS3_k127_5291454_11 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001452 263.0
TLS3_k127_5291454_12 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000275 246.0
TLS3_k127_5291454_13 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000007677 198.0
TLS3_k127_5291454_14 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000001392 197.0
TLS3_k127_5291454_15 FCD - - - 0.00000000000000000000000000000000000000425 157.0
TLS3_k127_5291454_16 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000005758 115.0
TLS3_k127_5291454_17 Pro-kumamolisin, activation domain K05999 - 3.4.21.101 0.00000000000000000000001206 118.0
TLS3_k127_5291454_18 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000001532 107.0
TLS3_k127_5291454_2 Peptidase S8 and S53, subtilisin, kexin, sedolisin K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 530.0
TLS3_k127_5291454_20 - - - - 0.000001652 59.0
TLS3_k127_5291454_3 Peptidase family M28 K05994 - 3.4.11.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 522.0
TLS3_k127_5291454_4 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 460.0
TLS3_k127_5291454_5 TIGRFAM TonB-dependent heme hemoglobin receptor family protein K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 415.0
TLS3_k127_5291454_6 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 335.0
TLS3_k127_5291454_7 Zinc metalloprotease (Elastase) K01399,K08604 - 3.4.24.25,3.4.24.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 336.0
TLS3_k127_5291454_8 Alpha-lytic protease prodomain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 321.0
TLS3_k127_5291454_9 asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 293.0
TLS3_k127_5346435_0 LssY C-terminus - - - 2.123e-261 820.0
TLS3_k127_5346435_1 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 1.97e-234 730.0
TLS3_k127_5346435_10 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000004253 221.0
TLS3_k127_5346435_11 rubredoxin - - - 0.0000000000000000000000000000001954 123.0
TLS3_k127_5346435_12 - - - - 0.00000000000000000000000000006361 115.0
TLS3_k127_5346435_13 - - - - 0.0000000005847 61.0
TLS3_k127_5346435_2 also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 3.086e-203 646.0
TLS3_k127_5346435_3 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 595.0
TLS3_k127_5346435_4 dehydrogenase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 495.0
TLS3_k127_5346435_5 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 387.0
TLS3_k127_5346435_6 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 383.0
TLS3_k127_5346435_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 264.0
TLS3_k127_5346435_8 Glyoxalase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000006649 249.0
TLS3_k127_5346435_9 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000000000000000000000005275 220.0
TLS3_k127_5352568_0 amino acid adenylation domain protein K04780 - - 0.0 4319.0
TLS3_k127_5352568_1 AcrB/AcrD/AcrF family K18138,K18142 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006855,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015238,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015307,GO:0015318,GO:0015672,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1902495,GO:1902600,GO:1990281,GO:1990351 - 0.0 1096.0
TLS3_k127_5352568_10 geranyltranstransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003311 265.0
TLS3_k127_5352568_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006771 234.0
TLS3_k127_5352568_12 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000001011 228.0
TLS3_k127_5352568_13 membrane - - - 0.000000000000000000000000000000000000575 143.0
TLS3_k127_5352568_14 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000003031 98.0
TLS3_k127_5352568_15 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000001584 87.0
TLS3_k127_5352568_2 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 1.123e-250 779.0
TLS3_k127_5352568_3 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 2.125e-220 700.0
TLS3_k127_5352568_4 FAD binding domain - - - 4.355e-202 673.0
TLS3_k127_5352568_5 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 520.0
TLS3_k127_5352568_6 Transmembrane secretion effector K00836 - 2.6.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 473.0
TLS3_k127_5352568_7 PFAM acyltransferase 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 454.0
TLS3_k127_5352568_8 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 378.0
TLS3_k127_5352568_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 374.0
TLS3_k127_5385465_0 ABC transporter substrate-binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 458.0
TLS3_k127_5385465_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 329.0
TLS3_k127_5385465_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.000000000000000007659 82.0
TLS3_k127_5398668_0 - - - - 2.085e-196 619.0
TLS3_k127_5398668_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000004085 110.0
TLS3_k127_5398668_2 Polysaccharide deacetylase - - - 0.00000001476 57.0
TLS3_k127_5408800_0 ATPase involved in DNA repair - - - 0.0 2472.0
TLS3_k127_5408800_1 Peptidase M16 - - - 0.0 1178.0
TLS3_k127_5408800_2 protein conserved in bacteria - - - 1.838e-309 959.0
TLS3_k127_5408800_3 synthase K22317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 585.0
TLS3_k127_5408800_4 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 296.0
TLS3_k127_5408800_5 Uncharacterized protein conserved in bacteria (DUF2170) K09980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001234 259.0
TLS3_k127_5408800_6 PspA/IM30 family K03969 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000002662 217.0
TLS3_k127_5408800_7 Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins - - - 0.0000000000000000000000000000000000000000000000000000008269 194.0
TLS3_k127_5408800_8 - - - - 0.000000000000000000000000000000000000000000000003311 181.0
TLS3_k127_5408800_9 Domain of unknown function (DUF4156) - - - 0.00000000000000000000000000000000000005538 151.0
TLS3_k127_5418513_0 membrane - - - 0.0 1022.0
TLS3_k127_5418513_1 COG0644 Dehydrogenases (flavoproteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 612.0
TLS3_k127_5418513_10 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.000000000000000000000000000000000000000000000000000000000000000000004048 247.0
TLS3_k127_5418513_11 Fatty acyl CoA synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000002607 234.0
TLS3_k127_5418513_12 membrane - - - 0.00000000000000000000000000000000000000000000000000259 201.0
TLS3_k127_5418513_13 acyl carrier protein K02078 - - 0.000000000000000000000000000000000002981 145.0
TLS3_k127_5418513_14 dehydratase - - - 0.0000000000000000000000000000000001597 146.0
TLS3_k127_5418513_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000286 121.0
TLS3_k127_5418513_16 membrane - - - 0.0000000000000000000000000721 108.0
TLS3_k127_5418513_17 Acetyltransferase (GNAT) domain - - - 0.0000000000000005574 91.0
TLS3_k127_5418513_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008106 575.0
TLS3_k127_5418513_3 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 538.0
TLS3_k127_5418513_4 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 467.0
TLS3_k127_5418513_5 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 431.0
TLS3_k127_5418513_6 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 415.0
TLS3_k127_5418513_7 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 410.0
TLS3_k127_5418513_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 393.0
TLS3_k127_5418513_9 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001125 286.0
TLS3_k127_5426468_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 1.441e-195 616.0
TLS3_k127_5426468_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 579.0
TLS3_k127_5426468_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 564.0
TLS3_k127_5426468_3 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 452.0
TLS3_k127_5426468_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 391.0
TLS3_k127_5426468_5 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
TLS3_k127_5426468_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 265.0
TLS3_k127_5426468_7 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000000000000000000000002953 159.0
TLS3_k127_5426468_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000001106 154.0
TLS3_k127_5453857_0 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0 1294.0
TLS3_k127_5453857_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000002199 211.0
TLS3_k127_5453857_2 non-ribosomal peptide synthetase - - - 0.000000000000000000000000003221 116.0
TLS3_k127_5453916_0 amino acid adenylation domain - - - 0.0 1872.0
TLS3_k127_5499237_0 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 551.0
TLS3_k127_5499237_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 385.0
TLS3_k127_5506552_0 major facilitator superfamily K03446 - - 4.301e-282 873.0
TLS3_k127_5506552_1 Multidrug resistance efflux pump K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 552.0
TLS3_k127_5529425_0 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 489.0
TLS3_k127_5529425_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001017 261.0
TLS3_k127_5547820_0 protein involved in benzoate metabolism K05782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 544.0
TLS3_k127_5547820_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 406.0
TLS3_k127_5547820_2 Alpha-lytic protease prodomain K18546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008304 275.0
TLS3_k127_5547820_3 Domain of unknown function (DUF4377) - - - 0.000000000000000000000000000000000000000000000000000000000000000001469 237.0
TLS3_k127_5547820_4 Alpha-lytic protease prodomain - - - 0.00000000000000000000000000000000000000000000000000000000000000000189 243.0
TLS3_k127_5547820_5 Bulb-type mannose-specific lectin - - - 0.000002662 59.0
TLS3_k127_5583352_0 ATP-binding protein K06915 - - 1.481e-279 865.0
TLS3_k127_5583352_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.4e-259 807.0
TLS3_k127_5583352_2 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 605.0
TLS3_k127_5583352_3 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 386.0
TLS3_k127_5583352_4 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 322.0
TLS3_k127_5583352_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 297.0
TLS3_k127_5583352_6 Protein tyrosine kinase K11912 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 306.0
TLS3_k127_5583352_7 - - - - 0.00000000000000000000000000000000000009387 153.0
TLS3_k127_5583352_8 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000123 111.0
TLS3_k127_5583352_9 - - - - 0.0000000000000000000000003824 113.0
TLS3_k127_5591069_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1125.0
TLS3_k127_5591069_1 3-hydroxyacyl-coa dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1120.0
TLS3_k127_5591069_10 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 422.0
TLS3_k127_5591069_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 367.0
TLS3_k127_5591069_12 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 344.0
TLS3_k127_5591069_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 336.0
TLS3_k127_5591069_14 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 328.0
TLS3_k127_5591069_15 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006361 277.0
TLS3_k127_5591069_16 CYTH domain protein K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000008553 265.0
TLS3_k127_5591069_17 Death-on-curing protein K07341 - - 0.00000000000000000000000000000000000000000000000000000000000000003383 227.0
TLS3_k127_5591069_18 COG0784 FOG CheY-like receiver - - - 0.000000000000000000000000000000000000000000000000000000005864 207.0
TLS3_k127_5591069_19 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000000000349 162.0
TLS3_k127_5591069_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 3.852e-266 826.0
TLS3_k127_5591069_20 Domain of unknown function (DUF4845) - - - 0.0000000000000000000000000000000000342 139.0
TLS3_k127_5591069_21 Anti sigma-E protein RseA, N-terminal domain - - - 0.00000000000000000000000000000000006546 145.0
TLS3_k127_5591069_22 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000002159 148.0
TLS3_k127_5591069_23 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000105 109.0
TLS3_k127_5591069_24 SpoVT / AbrB like domain - - - 0.0000000000000000000000003263 123.0
TLS3_k127_5591069_25 - - - - 0.000000000000000000000004653 110.0
TLS3_k127_5591069_26 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000000008395 81.0
TLS3_k127_5591069_27 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.0000000000001612 73.0
TLS3_k127_5591069_28 - - - - 0.0000001138 59.0
TLS3_k127_5591069_3 Protein conserved in bacteria - - - 4.043e-231 756.0
TLS3_k127_5591069_4 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 6.513e-223 699.0
TLS3_k127_5591069_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.746e-210 663.0
TLS3_k127_5591069_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 531.0
TLS3_k127_5591069_7 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 502.0
TLS3_k127_5591069_8 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 486.0
TLS3_k127_5591069_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 436.0
TLS3_k127_5620392_0 transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 424.0
TLS3_k127_5620392_1 transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 389.0
TLS3_k127_5620392_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 356.0
TLS3_k127_5620392_3 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 351.0
TLS3_k127_5620392_4 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 325.0
TLS3_k127_5620392_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 296.0
TLS3_k127_5620392_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000001743 220.0
TLS3_k127_5651722_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.892e-255 818.0
TLS3_k127_5651722_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 5.829e-211 690.0
TLS3_k127_5651722_2 transcriptional regulator K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 596.0
TLS3_k127_5651722_3 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 580.0
TLS3_k127_5651722_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 394.0
TLS3_k127_5651722_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000003306 201.0
TLS3_k127_5651866_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.609e-291 906.0
TLS3_k127_5651866_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 3.179e-196 614.0
TLS3_k127_5651866_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009287 385.0
TLS3_k127_5651866_3 Glycosyl hydrolases family 25 K07273 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003028 270.0
TLS3_k127_5738949_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1175.0
TLS3_k127_5738949_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 8.383e-213 674.0
TLS3_k127_5738949_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 409.0
TLS3_k127_5738949_3 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000001295 226.0
TLS3_k127_5738949_4 conserved protein UCP033924 - - - 0.000000000000000000000000000000000000000000000001627 179.0
TLS3_k127_5745893_0 transporter - - - 0.0 1071.0
TLS3_k127_5745893_1 Transporter K03305 - - 3.099e-244 775.0
TLS3_k127_5745893_2 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 322.0
TLS3_k127_5767306_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 361.0
TLS3_k127_5767306_1 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000002192 171.0
TLS3_k127_5801264_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18303 - - 0.0 1552.0
TLS3_k127_5801264_1 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 0.0 1146.0
TLS3_k127_5801264_2 Threonine synthase K01733 - 4.2.3.1 1.084e-201 640.0
TLS3_k127_5801264_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 466.0
TLS3_k127_5801264_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18302 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 377.0
TLS3_k127_5801264_5 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 295.0
TLS3_k127_5801264_6 Transcriptional regulator K18301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005436 275.0
TLS3_k127_5801264_7 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000116 78.0
TLS3_k127_5819520_0 Linear gramicidin synthase subunit - - - 0.0 1333.0
TLS3_k127_5819520_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1066.0
TLS3_k127_5819520_10 Branched-chain amino acid aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 398.0
TLS3_k127_5819520_11 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 332.0
TLS3_k127_5819520_12 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 312.0
TLS3_k127_5819520_13 glycerophosphoryl diester phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 294.0
TLS3_k127_5819520_14 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000809 281.0
TLS3_k127_5819520_15 HAD-hyrolase-like K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003539 246.0
TLS3_k127_5819520_16 geranyltranstransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000001321 231.0
TLS3_k127_5819520_17 Belongs to the P-Pant transferase superfamily - - - 0.0000000000000000000000000003142 132.0
TLS3_k127_5819520_18 Transposase IS116/IS110/IS902 family - - - 0.0005003 45.0
TLS3_k127_5819520_2 Condensation domain - - - 2.128e-295 960.0
TLS3_k127_5819520_3 Non-ribosomal peptide synthetase modules and related proteins - - - 5.163e-271 872.0
TLS3_k127_5819520_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis - - - 3.117e-206 673.0
TLS3_k127_5819520_5 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 608.0
TLS3_k127_5819520_6 uridine kinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 587.0
TLS3_k127_5819520_7 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 551.0
TLS3_k127_5819520_8 Transmembrane secretion effector K00836 - 2.6.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 503.0
TLS3_k127_5819520_9 Pfam:DUF2029 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 404.0
TLS3_k127_5830683_0 GGDEF domain - - - 3.033e-308 972.0
TLS3_k127_5830683_1 endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 581.0
TLS3_k127_5830683_10 - - - - 0.0000000000000000000000000000000000000000000000004897 186.0
TLS3_k127_5830683_11 phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000000000000000005255 173.0
TLS3_k127_5830683_12 EF-hand domain pair - - - 0.00000000000000000000000000006067 127.0
TLS3_k127_5830683_13 - - - - 0.000000000000006743 80.0
TLS3_k127_5830683_14 ISXO2-like transposase domain K07488 - - 0.0000000000009104 69.0
TLS3_k127_5830683_15 - - - - 0.00002997 47.0
TLS3_k127_5830683_2 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 500.0
TLS3_k127_5830683_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 500.0
TLS3_k127_5830683_4 RNA polymerase sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 433.0
TLS3_k127_5830683_5 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 412.0
TLS3_k127_5830683_6 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 406.0
TLS3_k127_5830683_7 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 376.0
TLS3_k127_5830683_8 RNA polymerase sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 338.0
TLS3_k127_5830683_9 MltA-interacting protein MipA K07274 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000004398 234.0
TLS3_k127_584057_0 cellulase activity - - - 0.0 1623.0
TLS3_k127_584057_1 MFS transporter K11381 - 1.2.4.4 0.0 1341.0
TLS3_k127_584057_10 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 386.0
TLS3_k127_584057_11 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 362.0
TLS3_k127_584057_12 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 346.0
TLS3_k127_584057_13 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 280.0
TLS3_k127_584057_14 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007835 273.0
TLS3_k127_584057_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004289 281.0
TLS3_k127_584057_16 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006172 261.0
TLS3_k127_584057_17 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000008811 238.0
TLS3_k127_584057_18 Transcription regulator MerR, DNA binding K21744 - - 0.0000000000000000000000000000000000000000000000000000000000003811 220.0
TLS3_k127_584057_19 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000121 206.0
TLS3_k127_584057_2 abc transporter atp-binding protein K06147 - - 1.079e-320 990.0
TLS3_k127_584057_20 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000001443 201.0
TLS3_k127_584057_21 protein conserved in bacteria K09793 - - 0.00000000000000000000000000000000000000000000000003676 199.0
TLS3_k127_584057_22 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000003722 171.0
TLS3_k127_584057_23 Outer membrane lipoprotein K06077 - - 0.00000000000000000000000000000000000001531 158.0
TLS3_k127_584057_24 - - - - 0.000000000000000000000000000395 122.0
TLS3_k127_584057_25 - - - - 0.0000000000000000006834 89.0
TLS3_k127_584057_26 - - - - 0.0000000000003201 75.0
TLS3_k127_584057_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.19e-312 966.0
TLS3_k127_584057_4 Amidohydrolase family - - - 4.87e-295 922.0
TLS3_k127_584057_5 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 2.327e-228 724.0
TLS3_k127_584057_6 ferredoxin--nadp reductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 464.0
TLS3_k127_584057_7 Lysine-specific metallo-endopeptidase K08646 - 3.4.24.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 457.0
TLS3_k127_584057_8 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 434.0
TLS3_k127_584057_9 Lysine-specific metallo-endopeptidase K08646 - 3.4.24.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 410.0
TLS3_k127_5891717_0 lipid binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 465.0
TLS3_k127_5891717_1 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 327.0
TLS3_k127_5891717_2 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001964 276.0
TLS3_k127_5891717_3 - - - - 0.000000000000000000000000000000000000000007036 157.0
TLS3_k127_5891717_4 - - - - 0.00000000000000000000000000000003632 136.0
TLS3_k127_5891717_5 Amidohydrolase family - - - 0.00000000000000000000000277 102.0
TLS3_k127_593167_0 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.0 1035.0
TLS3_k127_593167_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 473.0
TLS3_k127_593167_2 E3 component of 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.00000001854 57.0
TLS3_k127_5961583_0 ABC transporter transmembrane region K06147 - - 3.718e-206 651.0
TLS3_k127_5961583_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000008066 239.0
TLS3_k127_5961583_2 Protein of unknown function (DUF4031) - - - 0.00000000000000000000000000000003343 132.0
TLS3_k127_5975290_0 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 6.841e-214 674.0
TLS3_k127_5975290_1 amino acid - - - 2.112e-198 628.0
TLS3_k127_5975290_10 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000000000000000000000000000000000000000000381 231.0
TLS3_k127_5975290_11 - - - - 0.00000000000000000000000000000000000000000005154 164.0
TLS3_k127_5975290_12 GDYXXLXY protein - - - 0.00000000000000000000000000000000000000006482 161.0
TLS3_k127_5975290_2 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 554.0
TLS3_k127_5975290_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 445.0
TLS3_k127_5975290_4 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 455.0
TLS3_k127_5975290_5 chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 449.0
TLS3_k127_5975290_6 Dolichol-phosphate mannosyltransferase K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 410.0
TLS3_k127_5975290_7 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 300.0
TLS3_k127_5975290_8 carbonic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003735 304.0
TLS3_k127_5975290_9 membrane - - - 0.000000000000000000000000000000000000000000000000000000000003293 223.0
TLS3_k127_6023146_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 6.068e-314 974.0
TLS3_k127_6023146_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 394.0
TLS3_k127_6023146_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000742 269.0
TLS3_k127_6023146_3 Periplasmic protein thiol disulfide oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001703 245.0
TLS3_k127_6023146_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000000000000002994 232.0
TLS3_k127_6023146_5 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000003299 180.0
TLS3_k127_6023146_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000002439 60.0
TLS3_k127_6048276_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1428.0
TLS3_k127_6048276_1 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 2.47e-229 717.0
TLS3_k127_6048276_2 Oxidoreductase K09471 - - 3.027e-194 614.0
TLS3_k127_6048276_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 432.0
TLS3_k127_6048276_4 Glutamine K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 359.0
TLS3_k127_6048276_5 protein conserved in bacteria K09920 - - 0.00000000000000000000000000000000000000000000000000000000000000000003093 237.0
TLS3_k127_6048276_6 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000002408 222.0
TLS3_k127_6048276_8 - - - - 0.00000001723 58.0
TLS3_k127_6050549_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1672.0
TLS3_k127_6050549_1 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 514.0
TLS3_k127_6050549_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 320.0
TLS3_k127_6050549_3 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000008851 230.0
TLS3_k127_6050549_4 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000774 165.0
TLS3_k127_6052849_0 Spermine/spermidine synthase domain - - - 0.0 1072.0
TLS3_k127_6052849_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 5.913e-293 908.0
TLS3_k127_6052849_10 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 470.0
TLS3_k127_6052849_11 signal sequence binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001118 266.0
TLS3_k127_6052849_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000007081 258.0
TLS3_k127_6052849_13 SURF1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005737 237.0
TLS3_k127_6052849_14 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000000000000000000000000000000000002933 192.0
TLS3_k127_6052849_15 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000000000000000000000004892 162.0
TLS3_k127_6052849_16 PFAM cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.00000000000000000000000000000006275 128.0
TLS3_k127_6052849_17 Protein of unknown function (DUF2909) - - - 0.00000000000000000000000002785 120.0
TLS3_k127_6052849_2 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 1.566e-230 722.0
TLS3_k127_6052849_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.379e-221 690.0
TLS3_k127_6052849_4 Type II secretory pathway K02653 - - 1.732e-205 645.0
TLS3_k127_6052849_5 Amidohydrolase family - - - 2.464e-199 632.0
TLS3_k127_6052849_6 Histidine kinase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 548.0
TLS3_k127_6052849_7 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 526.0
TLS3_k127_6052849_8 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 515.0
TLS3_k127_6052849_9 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 492.0
TLS3_k127_6053551_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.642e-275 860.0
TLS3_k127_6053551_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 4.856e-260 816.0
TLS3_k127_6053551_2 Pectinacetylesterase - - - 9.243e-233 729.0
TLS3_k127_6053551_3 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009609 341.0
TLS3_k127_6053551_4 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000006324 160.0
TLS3_k127_6053551_5 - - - - 0.00000000000000000000000000000000000002442 145.0
TLS3_k127_6053551_6 - - - - 0.00000000000000000000000000000004802 136.0
TLS3_k127_6064517_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.399e-240 749.0
TLS3_k127_6064517_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.321e-230 734.0
TLS3_k127_6064517_10 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000000008364 140.0
TLS3_k127_6064517_11 DoxX K15977 - - 0.000000000000000000000000000003886 125.0
TLS3_k127_6064517_2 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 580.0
TLS3_k127_6064517_3 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 517.0
TLS3_k127_6064517_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 299.0
TLS3_k127_6064517_5 Sugar ABC transporter substrate-binding protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 294.0
TLS3_k127_6064517_6 to the N-terminal domain of Lon protease K07157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001064 271.0
TLS3_k127_6064517_7 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001647 272.0
TLS3_k127_6064517_8 arsR family - - - 0.000000000000000000000000000000000000000000000003584 175.0
TLS3_k127_6064517_9 LssY C-terminus - - - 0.00000000000000000000000000000000001881 138.0
TLS3_k127_6071891_0 Outer membrane receptor K02014 - - 0.0 1171.0
TLS3_k127_6071891_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.391e-275 852.0
TLS3_k127_6071891_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 595.0
TLS3_k127_6071891_3 PhoD-like phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 492.0
TLS3_k127_6071891_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 427.0
TLS3_k127_6071891_5 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 368.0
TLS3_k127_6071891_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 340.0
TLS3_k127_6071891_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 297.0
TLS3_k127_6071891_8 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000001941 66.0
TLS3_k127_61082_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 422.0
TLS3_k127_61082_1 Glycosyltransferase (GlcNAc) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008868 277.0
TLS3_k127_61082_2 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000003432 173.0
TLS3_k127_61082_3 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.0000000000000000000000000000008462 138.0
TLS3_k127_61082_5 - - - - 0.00003883 50.0
TLS3_k127_6164326_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 6.075e-268 829.0
TLS3_k127_6164326_1 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 3.969e-215 670.0
TLS3_k127_6164326_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 601.0
TLS3_k127_6164326_3 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 585.0
TLS3_k127_6164326_4 ABC-type spermidine putrescine transport system, permease component I K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 436.0
TLS3_k127_6164326_5 Spermidine putrescine ABC transporter permease K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 413.0
TLS3_k127_6164326_6 In Escherichia coli this enzyme appears to be an NAD NADP -dependent succinate semialdehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 313.0
TLS3_k127_6172347_0 receptor K16087 - - 8.559e-279 878.0
TLS3_k127_6172347_1 Peptidase M48 Ste24p - - - 1.222e-262 826.0
TLS3_k127_6172347_10 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 476.0
TLS3_k127_6172347_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 473.0
TLS3_k127_6172347_12 xyloglucan:xyloglucosyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 466.0
TLS3_k127_6172347_13 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 464.0
TLS3_k127_6172347_14 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 444.0
TLS3_k127_6172347_15 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 421.0
TLS3_k127_6172347_16 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 406.0
TLS3_k127_6172347_17 Transcriptional regulator K10914 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0017076,GO:0019001,GO:0019219,GO:0019222,GO:0030551,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032561,GO:0035438,GO:0036094,GO:0043167,GO:0043168,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 388.0
TLS3_k127_6172347_18 Pectate lyase K01728 - 4.2.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 370.0
TLS3_k127_6172347_19 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 299.0
TLS3_k127_6172347_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 7.74e-254 785.0
TLS3_k127_6172347_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001111 293.0
TLS3_k127_6172347_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004396 265.0
TLS3_k127_6172347_22 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000177 267.0
TLS3_k127_6172347_23 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000322 242.0
TLS3_k127_6172347_24 PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000002215 227.0
TLS3_k127_6172347_25 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000001022 210.0
TLS3_k127_6172347_26 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.000000000000000000000000000000000000000000000002114 177.0
TLS3_k127_6172347_27 iron ion transport - - - 0.00000000000000000000000000000000000000000009123 168.0
TLS3_k127_6172347_28 Domain of unknown function (DUF1508) K09946 - - 0.0000000000000000000000000000000000000000007044 160.0
TLS3_k127_6172347_29 DJ-1/PfpI family K18199 - 4.2.1.103 0.000000000000000000000000000000000000000773 160.0
TLS3_k127_6172347_3 Acetyltransferase (GNAT) domain - - - 9.717e-236 746.0
TLS3_k127_6172347_30 Transcription factor zinc-finger - - - 0.00000000000000000000000000002564 123.0
TLS3_k127_6172347_32 Hemin transporter HemP - - - 0.0000000001219 64.0
TLS3_k127_6172347_33 - - - - 0.000000000402 70.0
TLS3_k127_6172347_34 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00001553 57.0
TLS3_k127_6172347_4 Na dependent nucleoside transporter K03317 - - 4.903e-230 717.0
TLS3_k127_6172347_5 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 607.0
TLS3_k127_6172347_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 564.0
TLS3_k127_6172347_7 beta-lactamase K01467 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 565.0
TLS3_k127_6172347_8 potassium channel beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 516.0
TLS3_k127_6172347_9 membrane-bound metal-dependent K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 492.0
TLS3_k127_6173063_0 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 365.0
TLS3_k127_6173063_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000003003 219.0
TLS3_k127_6173063_2 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000000000000000000000006744 189.0
TLS3_k127_6173063_3 Domain of unknown function (DUF4166) - - - 0.0000000000000000000000000000000000000001334 163.0
TLS3_k127_6173063_4 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000009685 50.0
TLS3_k127_6199811_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.849e-199 642.0
TLS3_k127_6199811_1 multicopper - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001979 248.0
TLS3_k127_6199811_2 mercury ion transmembrane transporter activity K07089,K07213 - - 0.000000000001815 71.0
TLS3_k127_6199811_3 - - - - 0.0005002 48.0
TLS3_k127_6232974_0 RmuC family K09760 - - 1.251e-203 649.0
TLS3_k127_6232974_1 abc transporter atp-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 420.0
TLS3_k127_6232974_2 Lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 418.0
TLS3_k127_6232974_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 409.0
TLS3_k127_6232974_4 Organic solvent ABC transporter K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006101 260.0
TLS3_k127_6232974_5 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000001609 239.0
TLS3_k127_6232974_6 phenylacetate-CoA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000273 214.0
TLS3_k127_6232974_7 Oxidoreductase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000002565 191.0
TLS3_k127_6232974_8 Anti-sigma B factor antagonist K07122 - - 0.000000000000006634 86.0
TLS3_k127_6252328_0 Histidine kinase - - - 1.738e-194 615.0
TLS3_k127_6252328_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 524.0
TLS3_k127_6252328_10 - - - - 0.000001836 60.0
TLS3_k127_6252328_2 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 479.0
TLS3_k127_6252328_3 XRE family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 434.0
TLS3_k127_6252328_4 peptidoglycan-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 399.0
TLS3_k127_6252328_5 Peptidase family M23 K21472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001767 254.0
TLS3_k127_6252328_6 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000000000000000000000000209 213.0
TLS3_k127_6252328_7 Sap, sulfolipid-1-addressing protein - - - 0.0000000000000000000000000000000000000000000000004958 184.0
TLS3_k127_6252328_8 - - - - 0.00000000000001554 79.0
TLS3_k127_6252328_9 TerB-C domain - - - 0.0000004941 56.0
TLS3_k127_6282118_0 Peptidase S46 - - - 6.602e-241 766.0
TLS3_k127_6282118_1 Pyridine nucleotide-disulphide oxidoreductase - - - 1.681e-202 645.0
TLS3_k127_6282118_2 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 422.0
TLS3_k127_6282118_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 315.0
TLS3_k127_6282118_4 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001417 291.0
TLS3_k127_6282118_5 acetyltransferase K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000005621 218.0
TLS3_k127_6282118_6 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000001051 192.0
TLS3_k127_6282118_7 sterol desaturase - - - 0.0000000000000000000000000000000000001863 154.0
TLS3_k127_6282118_8 ECF sigma factor - - - 0.000000000000000000000000002049 119.0
TLS3_k127_6282118_9 - - - - 0.00000000000001568 75.0
TLS3_k127_6320060_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 399.0
TLS3_k127_6320060_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002143 273.0
TLS3_k127_6320060_3 - - - - 0.0000000000000000006171 87.0
TLS3_k127_6336280_0 Glycosyltransferase WbsX - - - 0.0 1294.0
TLS3_k127_6336280_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 1.63e-270 839.0
TLS3_k127_6336280_10 ABC-type polysaccharide polyol phosphate transport system, ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 496.0
TLS3_k127_6336280_11 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 486.0
TLS3_k127_6336280_12 electron transfer flavoprotein beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 451.0
TLS3_k127_6336280_13 2OG-Fe dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 349.0
TLS3_k127_6336280_14 maleylacetoacetate isomerase K01800 - 5.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 357.0
TLS3_k127_6336280_15 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 346.0
TLS3_k127_6336280_16 PFAM ABC-2 type transporter K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 327.0
TLS3_k127_6336280_17 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 308.0
TLS3_k127_6336280_18 Nad-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 312.0
TLS3_k127_6336280_19 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 312.0
TLS3_k127_6336280_2 Cystathionine beta-synthase K01697 - 4.2.1.22 9.331e-270 835.0
TLS3_k127_6336280_20 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004858 291.0
TLS3_k127_6336280_21 Cephalosporin hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006437 269.0
TLS3_k127_6336280_22 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009402 258.0
TLS3_k127_6336280_23 Protein of unknown function (DUF3050) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003583 250.0
TLS3_k127_6336280_24 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002385 233.0
TLS3_k127_6336280_25 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000001717 196.0
TLS3_k127_6336280_26 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000002156 189.0
TLS3_k127_6336280_27 Transcriptional regulator, LuxR family K07782 - - 0.000000000000000000000000000000000000000009762 168.0
TLS3_k127_6336280_28 Autoinducer synthase K13060,K13061 - 2.3.1.184 0.00000000000000000000000000000000000000002355 162.0
TLS3_k127_6336280_29 membrane K08987 - - 0.00000000000000000000000000000000000000002369 156.0
TLS3_k127_6336280_3 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA K06445 - - 3.512e-210 657.0
TLS3_k127_6336280_30 membrane - - - 0.000000000000000000000000000000000000002439 163.0
TLS3_k127_6336280_31 Protein of unknown function (DUF465) - - - 0.00000000000000000000000001552 114.0
TLS3_k127_6336280_32 Domain of unknown function (DUF4398) - - - 0.0000000000000000003739 93.0
TLS3_k127_6336280_33 Hemerythrin HHE cation binding domain - - - 0.0000000000001122 73.0
TLS3_k127_6336280_34 protein conserved in bacteria K09935 - - 0.00000001252 59.0
TLS3_k127_6336280_35 - - - - 0.0002859 50.0
TLS3_k127_6336280_4 cystathionine K01758 - 4.4.1.1 5.283e-209 655.0
TLS3_k127_6336280_5 twitching motility protein K02670 - - 1.33e-205 666.0
TLS3_k127_6336280_6 Major Facilitator Superfamily K03301 - - 6.017e-197 624.0
TLS3_k127_6336280_7 2-keto-4-pentenoate hydratase K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 577.0
TLS3_k127_6336280_8 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 577.0
TLS3_k127_6336280_9 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 529.0
TLS3_k127_6346101_0 Belongs to the aldehyde dehydrogenase family K00146,K09472 - 1.2.1.39,1.2.1.99 1.799e-276 855.0
TLS3_k127_6346101_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 1.971e-241 755.0
TLS3_k127_6346101_10 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000001174 205.0
TLS3_k127_6346101_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000007609 207.0
TLS3_k127_6346101_12 - - - - 0.00000000000000002899 87.0
TLS3_k127_6346101_13 Gene 25-like lysozyme - - - 0.00000000001565 73.0
TLS3_k127_6346101_2 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 2.646e-227 729.0
TLS3_k127_6346101_3 alanine dehydrogenase K00259 - 1.4.1.1 1.656e-217 678.0
TLS3_k127_6346101_4 Phage late control gene D protein (GPD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 641.0
TLS3_k127_6346101_5 type VI secretion protein K11896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 562.0
TLS3_k127_6346101_6 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 394.0
TLS3_k127_6346101_7 Phage-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 316.0
TLS3_k127_6346101_8 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 284.0
TLS3_k127_6346101_9 Type VI secretion, TssG - - - 0.0000000000000000000000000000000000000000000000000000000000997 230.0
TLS3_k127_6351345_0 Phosphopantetheine attachment site - - - 0.0 4106.0
TLS3_k127_6351345_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K13950 - 2.6.1.85 1.907e-222 711.0
TLS3_k127_6351345_10 PFAM transposase, IS4 family protein K07487 - - 0.000000000000004509 76.0
TLS3_k127_6351345_2 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain K00101,K15054 - 1.1.2.3,1.1.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 481.0
TLS3_k127_6351345_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 475.0
TLS3_k127_6351345_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 452.0
TLS3_k127_6351345_5 Aminotransferase class I and II K16423 - 2.6.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 409.0
TLS3_k127_6351345_6 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001281 244.0
TLS3_k127_6351345_7 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000002225 166.0
TLS3_k127_6351345_8 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 0.00000000000000000000000004885 109.0
TLS3_k127_6351345_9 Chorismate mutase type II K04782 - 4.2.99.21 0.0000000000000000009176 91.0
TLS3_k127_6351382_0 Non-ribosomal peptide synthetase modules and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 520.0
TLS3_k127_6351382_1 non-ribosomal peptide synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 450.0
TLS3_k127_641279_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 485.0
TLS3_k127_641279_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000004573 216.0
TLS3_k127_6436745_0 peptidase K07386 - - 2.649e-195 612.0
TLS3_k127_6436745_1 MFS transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 340.0
TLS3_k127_6459534_0 B12 binding domain - - - 3.226e-249 791.0
TLS3_k127_6459534_1 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 401.0
TLS3_k127_6459534_2 belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 327.0
TLS3_k127_6459534_3 protein-(glutamine-N5) methyltransferase activity K21786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 309.0
TLS3_k127_6459534_4 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006545 243.0
TLS3_k127_64870_0 Prolyl oligopeptidase family - - - 0.0 1103.0
TLS3_k127_64870_1 Patatin-like phospholipase - - - 5.343e-227 749.0
TLS3_k127_64870_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 2.243e-194 612.0
TLS3_k127_64870_3 B-1 B cell differentiation - - - 0.00000000000000105 88.0
TLS3_k127_6496171_0 aminopeptidase - - - 7.792e-289 902.0
TLS3_k127_6496171_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 391.0
TLS3_k127_6496171_2 protein involved in formation of curli polymers - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 387.0
TLS3_k127_6496171_3 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009695 270.0
TLS3_k127_6496171_4 Glycosyl hydrolases family 25 K07273 - - 0.0000000000000000000000000000000000006682 142.0
TLS3_k127_6498338_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 507.0
TLS3_k127_6498338_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 475.0
TLS3_k127_6498338_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 429.0
TLS3_k127_6498338_3 EamA-like transporter family K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 411.0
TLS3_k127_6498338_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 365.0
TLS3_k127_6498338_5 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000004012 231.0
TLS3_k127_6528845_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1246.0
TLS3_k127_6528845_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 6.833e-272 866.0
TLS3_k127_6528845_2 Receptor K02014 - - 2.744e-216 708.0
TLS3_k127_6528845_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 451.0
TLS3_k127_6528845_4 AraC family transcriptional regulator K07506 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008061 267.0
TLS3_k127_6528845_5 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001491 265.0
TLS3_k127_6528845_6 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000002094 134.0
TLS3_k127_6528845_7 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.0009906 45.0
TLS3_k127_6531844_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 359.0
TLS3_k127_6531844_1 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000001674 236.0
TLS3_k127_6531844_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000762 192.0
TLS3_k127_6531844_3 Domain of unknown function (DUF4124) - - - 0.0000000000000000000002808 104.0
TLS3_k127_6536198_0 catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 9.542e-202 642.0
TLS3_k127_6536198_1 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 350.0
TLS3_k127_6536198_2 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 310.0
TLS3_k127_6541642_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1140.0
TLS3_k127_6541642_1 receptor K16090 - - 0.0 1020.0
TLS3_k127_6541642_10 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 346.0
TLS3_k127_6541642_11 protein conserved in bacteria K09939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 332.0
TLS3_k127_6541642_12 Putative DNA-binding domain K09929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 320.0
TLS3_k127_6541642_13 Predicted periplasmic protein (DUF2271) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001181 267.0
TLS3_k127_6541642_14 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000148 249.0
TLS3_k127_6541642_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000205 208.0
TLS3_k127_6541642_16 - - - - 0.000000000000000000000000000000000000002151 158.0
TLS3_k127_6541642_17 - - - - 0.0000000000000000000000000000007799 139.0
TLS3_k127_6541642_18 EF hand - - - 0.00000000000000000000000000408 125.0
TLS3_k127_6541642_19 transcriptional regulator K07733 - - 0.0000000002065 65.0
TLS3_k127_6541642_2 DNA primase activity K06919 - - 2.26e-242 790.0
TLS3_k127_6541642_20 Mor transcription activator family - - - 0.0008767 48.0
TLS3_k127_6541642_3 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 610.0
TLS3_k127_6541642_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 414.0
TLS3_k127_6541642_5 abc transporter, permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 424.0
TLS3_k127_6541642_6 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 395.0
TLS3_k127_6541642_7 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 397.0
TLS3_k127_6541642_8 PkhD-type hydroxylase K07336 GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0033554,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 392.0
TLS3_k127_6541642_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 366.0
TLS3_k127_6558226_0 Pathogenicity protein K09800 - - 0.0 1399.0
TLS3_k127_6558226_1 membrane K07278 - - 2.784e-243 765.0
TLS3_k127_6558226_2 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000034 192.0
TLS3_k127_6558226_3 - - - - 0.00000001684 62.0
TLS3_k127_6558226_4 - - - - 0.0000004053 61.0
TLS3_k127_6574155_0 lacI family K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 605.0
TLS3_k127_6574155_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 533.0
TLS3_k127_6574155_2 Iron dicitrate transport regulator FecR K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 523.0
TLS3_k127_6574155_3 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 362.0
TLS3_k127_6574155_4 Transporter - - - 0.0000000000002258 71.0
TLS3_k127_6588714_0 Putative diguanylate phosphodiesterase - - - 1.874e-254 818.0
TLS3_k127_6588714_1 PAS fold - - - 9.718e-202 648.0
TLS3_k127_6588714_10 COG KOG0946 ER-Golgi vesicle-tethering protein p115 - - - 0.0000000000000007838 91.0
TLS3_k127_6588714_2 Necrosis inducing protein (NPP1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 362.0
TLS3_k127_6588714_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 338.0
TLS3_k127_6588714_4 Domain of unknown function (DUF1963) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006045 272.0
TLS3_k127_6588714_5 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000002971 175.0
TLS3_k127_6588714_6 Domain of unknown function (DUF4920) - - - 0.0000000000000000000000000000000000000000001728 169.0
TLS3_k127_6588714_7 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000004711 167.0
TLS3_k127_6588714_8 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000002543 143.0
TLS3_k127_6588714_9 Transposase IS200 like K07491 - - 0.00000000000000001475 84.0
TLS3_k127_6667470_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 3.701e-245 766.0
TLS3_k127_6667470_1 Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA K00253 - 1.3.8.4 3.177e-233 725.0
TLS3_k127_6667470_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 1.687e-219 684.0
TLS3_k127_6667470_3 Cardiolipin synthase K06132 - - 1.112e-197 632.0
TLS3_k127_6667470_4 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 366.0
TLS3_k127_6667470_5 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 329.0
TLS3_k127_6667470_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002734 263.0
TLS3_k127_6716992_0 Glycosyl hydrolases family 16 - - - 1.582e-234 732.0
TLS3_k127_6716992_1 transporter K02429 - - 9.413e-234 732.0
TLS3_k127_6716992_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000007494 115.0
TLS3_k127_6716992_3 Tryptophan halogenase K14266 - 1.14.19.9 0.0000000000000000000000001469 106.0
TLS3_k127_674435_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1187.0
TLS3_k127_674435_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 559.0
TLS3_k127_674435_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 532.0
TLS3_k127_674435_3 Protein of unknown function (DUF559) - - - 0.000000000000000000000129 112.0
TLS3_k127_674435_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000004883 86.0
TLS3_k127_674435_5 Thioesterase superfamily - - - 0.0005371 52.0
TLS3_k127_6802894_0 Oligopeptidase K01354 - 3.4.21.83 1.592e-257 812.0
TLS3_k127_6802894_1 Sulfate transporter K03321 - - 2.04e-250 782.0
TLS3_k127_6802894_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 340.0
TLS3_k127_6802894_11 multivesicular body membrane disassembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005074 277.0
TLS3_k127_6802894_12 Predicted integral membrane protein (DUF2269) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007469 250.0
TLS3_k127_6802894_13 membrane K09790 - - 0.000000000000000000000000000000000000000000000000000002828 194.0
TLS3_k127_6802894_14 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000001714 162.0
TLS3_k127_6802894_15 - - - - 0.00000000000000000000000002115 126.0
TLS3_k127_6802894_16 - - - - 0.0000000003681 74.0
TLS3_k127_6802894_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.145e-238 744.0
TLS3_k127_6802894_3 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 574.0
TLS3_k127_6802894_4 Histidine kinase K07645 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 503.0
TLS3_k127_6802894_5 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 475.0
TLS3_k127_6802894_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 454.0
TLS3_k127_6802894_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 389.0
TLS3_k127_6802894_8 protein conserved in bacteria K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 365.0
TLS3_k127_6802894_9 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 348.0
TLS3_k127_6871460_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000429 261.0
TLS3_k127_6871460_1 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000000000000000000000000385 194.0
TLS3_k127_6871460_3 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000004885 122.0
TLS3_k127_6884740_0 efflux transmembrane transporter activity - - - 4.825e-281 885.0
TLS3_k127_6884740_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 531.0
TLS3_k127_6884740_2 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 477.0
TLS3_k127_6884740_3 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 436.0
TLS3_k127_6884740_4 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 389.0
TLS3_k127_6884740_5 MbtH-like protein K05375 - - 0.000000000000000000000000000001796 121.0
TLS3_k127_6884740_6 non-ribosomal peptide synthetase - - - 0.00000000002068 73.0
TLS3_k127_6885115_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.265e-313 967.0
TLS3_k127_6885115_1 Threonine/Serine exporter, ThrE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 450.0
TLS3_k127_6885115_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 342.0
TLS3_k127_6885115_3 methyl-accepting chemotaxis protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000002247 198.0
TLS3_k127_6885115_4 dna-binding protein K03746 - - 0.00000000000000000000000000005037 132.0
TLS3_k127_6885115_5 Domain of unknown function (DUF4124) - - - 0.0000000000002869 76.0
TLS3_k127_6885115_6 Domain of unknown function (DUF4124) - - - 0.00003421 49.0
TLS3_k127_6886325_0 Serine dehydratase K01752 - 4.3.1.17 1.746e-270 844.0
TLS3_k127_6886325_1 Cytochrome B561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 297.0
TLS3_k127_6886325_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009707 250.0
TLS3_k127_6886325_3 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000002194 214.0
TLS3_k127_6886325_4 thiol-disulfide isomerase and - - - 0.000000000000000000000000006179 111.0
TLS3_k127_6886325_5 homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.00000000007303 63.0
TLS3_k127_6886325_6 Histidine kinase - - - 0.000000000426 70.0
TLS3_k127_6888298_0 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 0.0 1166.0
TLS3_k127_6888298_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.0 1001.0
TLS3_k127_6888298_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000003031 176.0
TLS3_k127_6888298_11 Zinc metalloprotease (Elastase) K01399,K08604 - 3.4.24.25,3.4.24.26 0.000000000000000000000000000000000000000000004294 172.0
TLS3_k127_6888298_12 - - - - 0.00000000000000000000000000000000000002633 156.0
TLS3_k127_6888298_13 energy transducer activity K03832,K07126 - - 0.000000000000000000000000000175 122.0
TLS3_k127_6888298_14 Fe2 transport system protein A K04758 - - 0.000000000000000000000000002431 113.0
TLS3_k127_6888298_15 CAAX protease self-immunity K07052 - - 0.00000000000000000000000001355 117.0
TLS3_k127_6888298_17 - - - - 0.00000000000000001147 97.0
TLS3_k127_6888298_2 Ferrous iron transport protein B K04759 - - 5e-324 1004.0
TLS3_k127_6888298_3 TonB dependent receptor - - - 2.249e-255 828.0
TLS3_k127_6888298_4 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 3.722e-205 644.0
TLS3_k127_6888298_5 carboxylase K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 485.0
TLS3_k127_6888298_6 enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 376.0
TLS3_k127_6888298_7 FeS assembly SUF system protein SufT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 319.0
TLS3_k127_6888298_8 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000437 202.0
TLS3_k127_6888298_9 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000000000000725 192.0
TLS3_k127_6890919_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2326.0
TLS3_k127_6890919_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K04090 - 1.2.7.8 0.0 2053.0
TLS3_k127_6890919_10 Putative capsular polysaccharide synthesis protein - - - 0.0000000000000000006019 101.0
TLS3_k127_6890919_11 Peptidase inhibitor I78 family - - - 0.000000000007128 73.0
TLS3_k127_6890919_12 Integrase, catalytic region - - - 0.00000000217 58.0
TLS3_k127_6890919_15 Domain of unknown function DUF11 - - - 0.00001547 59.0
TLS3_k127_6890919_16 protein kinase activity K12132 - 2.7.11.1 0.0005938 46.0
TLS3_k127_6890919_2 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 4.493e-245 764.0
TLS3_k127_6890919_3 Major facilitator superfamily K08151 - - 1.12e-202 638.0
TLS3_k127_6890919_4 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000001961 195.0
TLS3_k127_6890919_5 (barnase) inhibitor - - - 0.0000000000000000000000000000000000000001701 154.0
TLS3_k127_6890919_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000001149 145.0
TLS3_k127_6890919_7 Conserved repeat domain - - - 0.0000000000000000000000000000000000632 156.0
TLS3_k127_6890919_8 Ribonuclease - - - 0.00000000000000000000000000000000009593 140.0
TLS3_k127_6890919_9 - - - - 0.0000000000000000000000000000002444 145.0
TLS3_k127_6925080_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.655e-276 872.0
TLS3_k127_6925080_1 Methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 6.234e-243 759.0
TLS3_k127_6925080_2 Belongs to the arginase family K01479,K01480 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0030145,GO:0034641,GO:0042401,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 511.0
TLS3_k127_6925080_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 475.0
TLS3_k127_6925080_4 In Escherichia coli this enzyme appears to be an NAD NADP -dependent succinate semialdehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 440.0
TLS3_k127_69264_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1284.0
TLS3_k127_69264_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1219.0
TLS3_k127_69264_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 5.864e-223 700.0
TLS3_k127_69264_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 6.913e-194 614.0
TLS3_k127_69264_12 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 637.0
TLS3_k127_69264_13 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 577.0
TLS3_k127_69264_14 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 557.0
TLS3_k127_69264_15 Outer membrane receptor proteins mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 482.0
TLS3_k127_69264_16 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 438.0
TLS3_k127_69264_17 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 444.0
TLS3_k127_69264_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 385.0
TLS3_k127_69264_19 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 378.0
TLS3_k127_69264_2 NADH ubiquinone oxidoreductase subunit K00341 - 1.6.5.3 0.0 1153.0
TLS3_k127_69264_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 359.0
TLS3_k127_69264_21 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 376.0
TLS3_k127_69264_22 NADH dehydrogenase K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 345.0
TLS3_k127_69264_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 310.0
TLS3_k127_69264_24 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001605 271.0
TLS3_k127_69264_25 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 251.0
TLS3_k127_69264_26 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007791 237.0
TLS3_k127_69264_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000001855 215.0
TLS3_k127_69264_29 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000002018 180.0
TLS3_k127_69264_3 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1108.0
TLS3_k127_69264_30 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000000000172 172.0
TLS3_k127_69264_31 Preprotein translocase subunit SecG K03075 - - 0.00000000000000000000000000000000000000005542 158.0
TLS3_k127_69264_32 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000002281 150.0
TLS3_k127_69264_33 - - - - 0.00000000000003861 85.0
TLS3_k127_69264_34 - - - - 0.000000001334 70.0
TLS3_k127_69264_35 - - - - 0.000000007352 56.0
TLS3_k127_69264_4 Participates in both transcription termination and antitermination K02600 - - 7.896e-290 894.0
TLS3_k127_69264_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 6.037e-279 860.0
TLS3_k127_69264_6 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 2.58e-271 841.0
TLS3_k127_69264_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.148e-263 826.0
TLS3_k127_69264_8 Protein of unknown function (DUF1800) - - - 5.817e-258 834.0
TLS3_k127_69264_9 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.617e-241 752.0
TLS3_k127_6929778_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 5.188e-213 669.0
TLS3_k127_6929778_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 441.0
TLS3_k127_6929778_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 421.0
TLS3_k127_6929778_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000001252 192.0
TLS3_k127_6929778_4 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000002416 198.0
TLS3_k127_6962425_0 His Kinase A (phosphoacceptor) domain K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 589.0
TLS3_k127_6962425_2 SURF1 family K14998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 315.0
TLS3_k127_6962425_3 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001299 269.0
TLS3_k127_6962425_4 cytochrome o ubiquinol oxidase subunit III K02299 - - 0.0000000000000000000000000000000000000000000000000008168 183.0
TLS3_k127_6962425_5 Prokaryotic Cytochrome C oxidase subunit IV K02300 - - 0.0000000000000000000000000000000000000000000000008417 183.0
TLS3_k127_6962425_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000002462 113.0
TLS3_k127_7000614_0 Heat shock 70 kDa protein K04043 - - 0.0 1080.0
TLS3_k127_7000614_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 8.323e-206 644.0
TLS3_k127_7000614_2 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 497.0
TLS3_k127_7000614_3 Predicted metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000004042 160.0
TLS3_k127_703080_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 523.0
TLS3_k127_703080_1 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 466.0
TLS3_k127_703080_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 395.0
TLS3_k127_703080_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 365.0
TLS3_k127_703080_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 347.0
TLS3_k127_703080_5 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000001844 223.0
TLS3_k127_703080_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000008634 168.0
TLS3_k127_703080_7 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000003425 115.0
TLS3_k127_703080_8 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000244 60.0
TLS3_k127_7044163_0 non-ribosomal peptide synthetase - - - 0.0 1143.0
TLS3_k127_7044163_1 Chitinase class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 480.0
TLS3_k127_7044163_2 3-Demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 295.0
TLS3_k127_7044163_4 virion core protein (lumpy skin disease virus) - - - 0.000000000000000000000000000000000002806 138.0
TLS3_k127_7046206_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 3.477e-297 918.0
TLS3_k127_7046206_1 3-beta hydroxysteroid dehydrogenase K22320 - 1.1.1.412 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 412.0
TLS3_k127_7046206_2 Sterol-binding protein K03690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000256 276.0
TLS3_k127_7055874_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0 1272.0
TLS3_k127_7055874_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.94e-197 616.0
TLS3_k127_7055874_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 525.0
TLS3_k127_7055874_3 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 477.0
TLS3_k127_7055874_4 Protein of unknown function (DUF3011) - - - 0.0000000000000000000000000000000000000000000000000001205 201.0
TLS3_k127_7055923_0 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 553.0
TLS3_k127_7055923_1 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 437.0
TLS3_k127_7055923_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886,K16066 - 1.1.1.276,1.1.1.381 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 396.0
TLS3_k127_7055923_4 Cell division protein - - - 0.0000000000000000000000000000000000000000000000000000000000002195 228.0
TLS3_k127_7055923_5 Putative inner membrane exporter, YdcZ - - - 0.0000000000000000000000000000000000001384 156.0
TLS3_k127_7055923_6 - - - - 0.000005895 55.0
TLS3_k127_7073141_0 asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 485.0
TLS3_k127_7073141_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000002604 168.0
TLS3_k127_7073141_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000008497 168.0
TLS3_k127_7073141_3 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000001073 147.0
TLS3_k127_7073141_4 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000006332 111.0
TLS3_k127_7083841_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.739e-258 824.0
TLS3_k127_7083841_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 3.48e-212 661.0
TLS3_k127_7083841_2 Peptidoglycan polymerase that is essential for cell division K03588 - - 1.149e-206 668.0
TLS3_k127_7083841_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 496.0
TLS3_k127_7083841_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000001421 149.0
TLS3_k127_7140225_0 Tryptophan halogenase - - - 3.883e-253 788.0
TLS3_k127_7140225_1 Major facilitator superfamily K16211 - - 1.725e-236 740.0
TLS3_k127_7149218_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 3.007e-199 651.0
TLS3_k127_7149218_1 DNA repair photolyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 550.0
TLS3_k127_7149218_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001946 273.0
TLS3_k127_7149218_3 Pfam:DUF955 - - - 0.0000000000003505 70.0
TLS3_k127_7149218_4 - - - - 0.00000000000101 74.0
TLS3_k127_7150534_0 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 383.0
TLS3_k127_7150534_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000257 271.0
TLS3_k127_7166601_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1615.0
TLS3_k127_7166601_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.204e-248 773.0
TLS3_k127_7166601_10 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000000000005736 177.0
TLS3_k127_7166601_11 Ribosomal protein L31 K02909 - - 0.000000000000000000000000000000000000000005089 155.0
TLS3_k127_7166601_12 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000792 139.0
TLS3_k127_7166601_13 Putative phosphatase (DUF442) - - - 0.000000000000000000000000000000000153 143.0
TLS3_k127_7166601_14 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000004035 114.0
TLS3_k127_7166601_2 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 3.789e-238 739.0
TLS3_k127_7166601_3 Zn-dependent hydrolases including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 445.0
TLS3_k127_7166601_4 Belongs to the IUNH family K01239 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 451.0
TLS3_k127_7166601_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 387.0
TLS3_k127_7166601_6 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002674 271.0
TLS3_k127_7166601_7 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000047 206.0
TLS3_k127_7166601_8 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000008541 205.0
TLS3_k127_7166601_9 Helicase K03578 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000007027 197.0
TLS3_k127_7175034_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1082.0
TLS3_k127_7175034_1 Peptidase family M48 - - - 0.0000000000000001057 85.0
TLS3_k127_7176047_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02298 - 1.10.3.10 0.0 1175.0
TLS3_k127_7176047_1 Sugar (and other) transporter - - - 3.882e-225 705.0
TLS3_k127_7176047_10 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000002014 207.0
TLS3_k127_7176047_11 - - - - 0.000000000000000000000000000000003166 135.0
TLS3_k127_7176047_12 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000005956 130.0
TLS3_k127_7176047_13 Molybdopterin K03636 - - 0.0000000000000000000000000103 114.0
TLS3_k127_7176047_14 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000002854 73.0
TLS3_k127_7176047_2 heptosyltransferase K12982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 599.0
TLS3_k127_7176047_3 ubiquinol oxidase subunit K02297 - 1.10.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 522.0
TLS3_k127_7176047_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 522.0
TLS3_k127_7176047_5 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 447.0
TLS3_k127_7176047_6 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 336.0
TLS3_k127_7176047_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000001516 264.0
TLS3_k127_7176047_8 cytochrome o ubiquinol oxidase subunit III K02299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000878 259.0
TLS3_k127_7176047_9 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000001414 216.0
TLS3_k127_7184818_0 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 4.809e-276 860.0
TLS3_k127_7184818_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 584.0
TLS3_k127_7184818_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 522.0
TLS3_k127_7184818_3 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 505.0
TLS3_k127_7184818_4 DNA-(Apurinic or apyrimidinic site) lyase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 467.0
TLS3_k127_7184818_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 331.0
TLS3_k127_7184818_6 - - - - 0.00000000000000000000000000000000000000003692 162.0
TLS3_k127_7184818_7 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000001194 139.0
TLS3_k127_7184818_8 - - - - 0.00000000000000000000000609 106.0
TLS3_k127_72020_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 4.097e-273 845.0
TLS3_k127_72020_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 534.0
TLS3_k127_72020_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 389.0
TLS3_k127_7203594_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0 1343.0
TLS3_k127_7203594_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0 1061.0
TLS3_k127_7203594_10 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004979 267.0
TLS3_k127_7203594_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000318 262.0
TLS3_k127_7203594_12 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000148 216.0
TLS3_k127_7203594_13 Clostripain family - - - 0.00000000000000000000000000000000000000000000000000000000008688 220.0
TLS3_k127_7203594_14 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.0000000000000000000000000000000000000000000000000000000001713 214.0
TLS3_k127_7203594_15 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.0000000000000000003369 86.0
TLS3_k127_7203594_2 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1055.0
TLS3_k127_7203594_3 HAD superfamily, subfamily IIIB (Acid phosphatase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 413.0
TLS3_k127_7203594_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 407.0
TLS3_k127_7203594_5 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 362.0
TLS3_k127_7203594_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 352.0
TLS3_k127_7203594_7 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 319.0
TLS3_k127_7203594_8 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 291.0
TLS3_k127_7203594_9 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002123 278.0
TLS3_k127_7203656_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1468.0
TLS3_k127_7203656_1 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 6.983e-318 982.0
TLS3_k127_7203656_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.891e-239 749.0
TLS3_k127_7203656_3 Tyrosine recombinase xerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 496.0
TLS3_k127_7203656_4 overlaps another CDS with the same product name K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 501.0
TLS3_k127_7203656_5 permease K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 446.0
TLS3_k127_7203656_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003038 280.0
TLS3_k127_7203656_7 dna polymerase III K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000001184 226.0
TLS3_k127_7203656_8 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000827 209.0
TLS3_k127_7205063_0 RHS Repeat - - - 0.0 1064.0
TLS3_k127_7205063_1 Peptidase, M13 K07386 - - 1.71e-264 831.0
TLS3_k127_7205063_10 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 569.0
TLS3_k127_7205063_11 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 492.0
TLS3_k127_7205063_12 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 453.0
TLS3_k127_7205063_13 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 407.0
TLS3_k127_7205063_14 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 331.0
TLS3_k127_7205063_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 324.0
TLS3_k127_7205063_16 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 319.0
TLS3_k127_7205063_17 Poly(R)-hydroxyalkanoic acid synthase subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 314.0
TLS3_k127_7205063_18 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001757 260.0
TLS3_k127_7205063_19 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007736 260.0
TLS3_k127_7205063_2 peptidase K07386 - - 3.639e-263 828.0
TLS3_k127_7205063_20 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008391 231.0
TLS3_k127_7205063_21 - - - - 0.00000000000000000000000000000000000000000000000000000000002637 209.0
TLS3_k127_7205063_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000001017 214.0
TLS3_k127_7205063_23 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000000000000000000000005293 178.0
TLS3_k127_7205063_24 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000002496 168.0
TLS3_k127_7205063_25 - - - - 0.000000000000000000000000000000000001376 143.0
TLS3_k127_7205063_26 Outer Membrane Lipoprotein K03098 - - 0.000000000000000000000000000000000005656 147.0
TLS3_k127_7205063_27 polysaccharide deacetylase - - - 0.000000000000000000000000000000494 133.0
TLS3_k127_7205063_28 Family of unknown function (DUF5329) - - - 0.000000000000000000000000000001299 137.0
TLS3_k127_7205063_29 - - - - 0.0000000000000000000000000005418 124.0
TLS3_k127_7205063_3 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 2.297e-231 723.0
TLS3_k127_7205063_30 - - - - 0.000000000000000000000001519 114.0
TLS3_k127_7205063_31 Stress-responsive transcriptional regulator - - - 0.000000000000000000007077 95.0
TLS3_k127_7205063_32 Lipocalin-like domain K03098 - - 0.000000000002318 72.0
TLS3_k127_7205063_33 Domain of unknown function (DUF4142) K08995 - - 0.000007465 55.0
TLS3_k127_7205063_4 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 5.085e-207 655.0
TLS3_k127_7205063_5 synthase K00574 - 2.1.1.79 4.537e-203 648.0
TLS3_k127_7205063_6 NAD FAD-binding protein K06954 - - 2.979e-201 652.0
TLS3_k127_7205063_7 synthase K00574 - 2.1.1.79 2.349e-194 612.0
TLS3_k127_7205063_8 alpha/beta hydrolase fold K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 604.0
TLS3_k127_7205063_9 3HB-oligomer hydrolase (3HBOH) K07518 - 3.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 596.0
TLS3_k127_7288973_0 7TMR-DISM extracellular 2 - - - 2.757e-253 794.0
TLS3_k127_7288973_1 calcineurin phosphoesterase - - - 1.752e-197 629.0
TLS3_k127_7288973_2 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 574.0
TLS3_k127_7288973_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 417.0
TLS3_k127_7288973_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 416.0
TLS3_k127_7288973_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 327.0
TLS3_k127_7288973_6 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001043 280.0
TLS3_k127_7288973_7 Bacterial PH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001189 280.0
TLS3_k127_7288973_8 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001569 282.0
TLS3_k127_7288973_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000001671 248.0
TLS3_k127_7315132_0 MASE1 - - - 4.119e-208 671.0
TLS3_k127_7315132_1 alkaline phosphatase activity K01077,K01126 - 3.1.3.1,3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 588.0
TLS3_k127_7315132_2 PFAM Serine dehydratase alpha chain K01752 GO:0003674,GO:0003824,GO:0003941,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001436 264.0
TLS3_k127_7315132_3 Outer membrane protein beta-barrel family K16089 - - 0.000000004609 59.0
TLS3_k127_7371849_0 - - - - 5.895e-291 909.0
TLS3_k127_7371849_1 - - - - 2.155e-206 645.0
TLS3_k127_7371849_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 480.0
TLS3_k127_7371849_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 460.0
TLS3_k127_7418613_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1327.0
TLS3_k127_7418613_1 abc transporter atp-binding protein K06158 - - 1.211e-297 925.0
TLS3_k127_7418613_2 Outer membrane receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 544.0
TLS3_k127_7418613_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 287.0
TLS3_k127_7418613_4 Regulatory protein, FmdB family - - - 0.000000000000000000000000000000000000002577 150.0
TLS3_k127_7418613_5 Hemerythrin HHE cation binding domain - - - 0.0000000000009961 78.0
TLS3_k127_7485917_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1309.0
TLS3_k127_7485917_1 Penicillin acylase K01434 - 3.5.1.11 0.0 1039.0
TLS3_k127_7485917_2 Sulfite reductase, alpha subunit (Flavoprotein) K00380 - 1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 591.0
TLS3_k127_7485917_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 360.0
TLS3_k127_7485917_4 abc transporter, permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 306.0
TLS3_k127_7485917_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 307.0
TLS3_k127_7485917_6 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000001257 168.0
TLS3_k127_7493013_0 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 297.0
TLS3_k127_7493013_1 Cytochrome C biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000008646 208.0
TLS3_k127_7493013_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000008221 127.0
TLS3_k127_7493013_3 - - - - 0.0000000000000000004564 90.0
TLS3_k127_7529885_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 379.0
TLS3_k127_7529885_1 transcriptional regulator K07734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 294.0
TLS3_k127_7529885_2 Formamidopyrimidine-DNA glycosylase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 268.0
TLS3_k127_7529885_3 PilZ domain - - - 0.0000000000000000000000000004691 119.0
TLS3_k127_7536019_0 Belongs to the ompA family - - - 3.441e-230 724.0
TLS3_k127_7536019_1 Belongs to the thiolase family K00626 - 2.3.1.9 2.849e-207 655.0
TLS3_k127_7536019_10 - - - - 0.000000000000000000000000000000000006218 141.0
TLS3_k127_7536019_11 protein conserved in bacteria K09924 - - 0.000000000000000000000000003524 126.0
TLS3_k127_7536019_12 - - - - 0.000000000000000000000001346 114.0
TLS3_k127_7536019_13 - - - - 0.0000000000000000000003986 106.0
TLS3_k127_7536019_2 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 554.0
TLS3_k127_7536019_3 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 397.0
TLS3_k127_7536019_4 Pfam Binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 388.0
TLS3_k127_7536019_5 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 299.0
TLS3_k127_7536019_6 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000008955 218.0
TLS3_k127_7536019_7 phage shock protein A, PspA K03969 - - 0.0000000000000000000000000000000000000000000000000000000000007594 218.0
TLS3_k127_7536019_8 Protein chain release factor B K15034 - - 0.0000000000000000000000000000000000000000000000000002125 189.0
TLS3_k127_7536019_9 pseudouridylate synthase K06175 - 5.4.99.26 0.0000000000000000000000000000000000005097 140.0
TLS3_k127_7632332_0 DNA helicase K03654 - 3.6.4.12 3.218e-209 655.0
TLS3_k127_7632332_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000008599 234.0
TLS3_k127_7632332_2 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000000000000000000000008677 192.0
TLS3_k127_7696737_0 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 483.0
TLS3_k127_7696737_1 Restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000000000002685 176.0
TLS3_k127_771703_0 Acyltransferase - - - 3.18e-228 715.0
TLS3_k127_771703_1 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.000000000000000000000000000000000008895 158.0
TLS3_k127_771703_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A - - - 0.00000000000000000000000001189 113.0
TLS3_k127_771703_3 transcriptional regulators - - - 0.0000000000000000000002959 100.0
TLS3_k127_7727035_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000675 256.0
TLS3_k127_7727035_1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000007361 243.0
TLS3_k127_7727035_2 GNAT acetyltransferase - - - 0.000000000000000000000000000000004185 134.0
TLS3_k127_7752188_0 hemolysin III K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 351.0
TLS3_k127_7752188_1 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 286.0
TLS3_k127_7752188_2 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001154 254.0
TLS3_k127_7752188_3 Sensors of blue-light using FAD - - - 0.0000000000000000001135 93.0
TLS3_k127_7756297_0 long-chain fatty acid transport protein - - - 0.0 1664.0
TLS3_k127_7756297_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.552e-320 989.0
TLS3_k127_7756297_10 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000009277 222.0
TLS3_k127_7756297_2 Domain of unknown function DUF11 - - - 1.248e-228 740.0
TLS3_k127_7756297_3 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 503.0
TLS3_k127_7756297_4 X-Pro dipeptidyl-peptidase K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 416.0
TLS3_k127_7756297_5 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 407.0
TLS3_k127_7756297_6 Large extracellular alpha-helical protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 318.0
TLS3_k127_7756297_7 Conserved repeat domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002415 287.0
TLS3_k127_7756297_8 Cache 3/Cache 2 fusion domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001821 269.0
TLS3_k127_7756297_9 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001453 242.0
TLS3_k127_7783315_0 Common central domain of tyrosinase K00505 - 1.14.18.1 4.155e-248 783.0
TLS3_k127_7783315_1 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 542.0
TLS3_k127_7783315_2 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 306.0
TLS3_k127_7783315_3 - - - - 0.0000000000000000000000000000003174 126.0
TLS3_k127_7805965_0 Belongs to the glutamate synthase family - - - 2.048e-283 881.0
TLS3_k127_7805965_1 Type IV secretory pathway, VirD4 K03205 - - 9.78e-275 854.0
TLS3_k127_7805965_10 Transglycosylase SLT domain K03194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001864 256.0
TLS3_k127_7805965_11 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008097 244.0
TLS3_k127_7805965_12 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000000000000000009653 231.0
TLS3_k127_7805965_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000002765 232.0
TLS3_k127_7805965_14 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000005924 143.0
TLS3_k127_7805965_15 Helix-turn-helix domain K07729 - - 0.00000000000000000000000002389 113.0
TLS3_k127_7805965_16 Sugar efflux transporter for intercellular exchange K15383 - - 0.00000000000000000000000004764 119.0
TLS3_k127_7805965_17 - - - - 0.00000000000000000000008527 108.0
TLS3_k127_7805965_2 protein conserved in bacteria - - - 1.01e-269 843.0
TLS3_k127_7805965_3 Amidohydrolase family - - - 2.179e-225 705.0
TLS3_k127_7805965_4 Protein tyrosine kinase K11912 - 2.7.11.1 1.127e-204 658.0
TLS3_k127_7805965_5 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 545.0
TLS3_k127_7805965_6 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 443.0
TLS3_k127_7805965_7 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 402.0
TLS3_k127_7805965_8 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 347.0
TLS3_k127_7805965_9 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003303 286.0
TLS3_k127_7811904_0 COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain K13409 - - 1.06e-237 756.0
TLS3_k127_7811904_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 464.0
TLS3_k127_7811904_2 Circularly permuted ATP-grasp type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 317.0
TLS3_k127_7811904_3 Ribosomal protein S6 modification - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 297.0
TLS3_k127_7811904_4 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.00000000000000000000000000000000000000000000000003081 184.0
TLS3_k127_7811904_5 ECF sigma factor - - - 0.000000000000000000000000000000000000000002746 166.0
TLS3_k127_7811904_6 HlyD family secretion protein K13408 - - 0.0000000000000001338 89.0
TLS3_k127_78422_0 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 366.0
TLS3_k127_78422_1 Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 309.0
TLS3_k127_78422_2 Protein of unknown function (DUF2752) - - - 0.000000000000000000000000000000000000000000000000001198 192.0
TLS3_k127_78422_3 - - - - 0.000000000000000000000000000000000000000001116 165.0
TLS3_k127_78422_4 Interferon-induced transmembrane protein - - - 0.000000000000000000000000000000000000002167 150.0
TLS3_k127_78422_5 Interferon-induced transmembrane protein - - - 0.000000000000000000000000000002733 126.0
TLS3_k127_7856526_0 Bacterial protein of unknown function (DUF885) - - - 2.419e-266 835.0
TLS3_k127_7856526_1 haemagglutination activity domain - - - 5.628e-208 691.0
TLS3_k127_7856526_10 Large extracellular alpha-helical protein - - - 0.00000000000000000000000000001507 131.0
TLS3_k127_7856526_11 Transcriptional regulator - - - 0.0003276 44.0
TLS3_k127_7856526_2 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 1.231e-207 661.0
TLS3_k127_7856526_3 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 459.0
TLS3_k127_7856526_4 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 439.0
TLS3_k127_7856526_5 peptidase K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 397.0
TLS3_k127_7856526_6 Nacht domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 420.0
TLS3_k127_7856526_7 Protein of unknown function (DUF1176) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 300.0
TLS3_k127_7856526_8 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000005511 214.0
TLS3_k127_7856526_9 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000946 161.0
TLS3_k127_7864144_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.93e-292 905.0
TLS3_k127_7864144_1 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 499.0
TLS3_k127_7864144_2 antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 376.0
TLS3_k127_7864144_3 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000000000000000000000000002932 199.0
TLS3_k127_7864144_4 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000006409 161.0
TLS3_k127_7864144_5 Acetyltransferase (GNAT) K06977 - - 0.00000000000000000000000000000000000000001342 172.0
TLS3_k127_7864144_6 Belongs to the transcriptional regulatory Fis family K03557 GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0032991,GO:0032993,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815 - 0.000000000000000000000000000000000000387 149.0
TLS3_k127_7864144_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000534 159.0
TLS3_k127_7864144_8 - - - - 0.000001851 59.0
TLS3_k127_7866026_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 419.0
TLS3_k127_7866026_1 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 375.0
TLS3_k127_7866026_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 362.0
TLS3_k127_7866026_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 345.0
TLS3_k127_7866026_4 DNA mismatch repair protein MutT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002343 248.0
TLS3_k127_7866026_5 Peptidyl-prolyl cis-trans K01802,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001365 243.0
TLS3_k127_7866026_6 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000000000264 167.0
TLS3_k127_7866026_7 ArsC family K00537,K03741 - 1.20.4.1 0.0000000000000000000000000000000000195 148.0
TLS3_k127_7866026_8 Protein of unknown function (DUF1289) - - - 0.000000000000000004606 86.0
TLS3_k127_7866026_9 Part of a membrane complex involved in electron transport - - - 0.000005005 60.0
TLS3_k127_7870036_0 protein conserved in bacteria - - - 1.103e-280 875.0
TLS3_k127_7870036_1 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 1.859e-270 837.0
TLS3_k127_7870036_10 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 330.0
TLS3_k127_7870036_11 exonuclease K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 299.0
TLS3_k127_7870036_12 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000105 235.0
TLS3_k127_7870036_13 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000005578 230.0
TLS3_k127_7870036_15 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000001742 184.0
TLS3_k127_7870036_16 - - - - 0.00000000000000000000000000000000000000004041 160.0
TLS3_k127_7870036_17 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000003873 149.0
TLS3_k127_7870036_18 - - - - 0.000000000000000000000000000000001551 131.0
TLS3_k127_7870036_19 TonB C terminal - - - 0.00000000000000000000009957 103.0
TLS3_k127_7870036_2 fad dependent oxidoreductase K07137 - - 4.674e-261 814.0
TLS3_k127_7870036_20 this gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.0000000000000000002062 104.0
TLS3_k127_7870036_21 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000004671 80.0
TLS3_k127_7870036_22 Lipase (class 3) - - - 0.0000000000008325 80.0
TLS3_k127_7870036_23 fad dependent oxidoreductase K07137 - - 0.000003364 53.0
TLS3_k127_7870036_24 fad dependent oxidoreductase K07137 - - 0.00008896 51.0
TLS3_k127_7870036_3 Beta-lactamase - - - 1.014e-254 798.0
TLS3_k127_7870036_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.553e-252 787.0
TLS3_k127_7870036_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 8.435e-242 769.0
TLS3_k127_7870036_6 Protein of unknown function (DUF1298) - - - 8.483e-241 752.0
TLS3_k127_7870036_7 Belongs to the DNA photolyase family K01669 - 4.1.99.3 2.216e-219 694.0
TLS3_k127_7870036_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids - - - 1.035e-208 655.0
TLS3_k127_7870036_9 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 591.0
TLS3_k127_7872317_0 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1289.0
TLS3_k127_7872317_1 acyl-coa dehydrogenase K09456 - - 2.135e-226 716.0
TLS3_k127_7872317_2 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 581.0
TLS3_k127_7872317_3 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 533.0
TLS3_k127_7872317_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 440.0
TLS3_k127_7872317_5 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 308.0
TLS3_k127_7872317_6 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002147 245.0
TLS3_k127_7872317_7 Cold shock protein domain - - - 0.0000000000000000000000000000003277 128.0
TLS3_k127_7876866_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 589.0
TLS3_k127_7876866_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 573.0
TLS3_k127_7876866_2 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 356.0
TLS3_k127_7876866_3 Protein of unknown function (DUF3011) - - - 0.00000000000000000000000000000000007 142.0
TLS3_k127_7876866_4 - - - - 0.0000000000000000000000000000000549 137.0
TLS3_k127_7876866_5 EF hand - - - 0.000000003523 57.0
TLS3_k127_7876866_6 EF hand - - - 0.000001334 57.0
TLS3_k127_7877768_0 dna polymerase K02337 - 2.7.7.7 0.0 1834.0
TLS3_k127_7877768_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1199.0
TLS3_k127_7877768_10 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 572.0
TLS3_k127_7877768_11 Sulfate adenylyltransferase subunit 2 K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 560.0
TLS3_k127_7877768_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 552.0
TLS3_k127_7877768_13 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 528.0
TLS3_k127_7877768_14 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 518.0
TLS3_k127_7877768_15 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 519.0
TLS3_k127_7877768_16 abc transporter, permease K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 521.0
TLS3_k127_7877768_17 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0050311,GO:0055114 1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 484.0
TLS3_k127_7877768_18 Part of SUF system involved in inserting iron-sulfur clusters into proteins K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 469.0
TLS3_k127_7877768_19 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 472.0
TLS3_k127_7877768_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 9.843e-316 993.0
TLS3_k127_7877768_20 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 427.0
TLS3_k127_7877768_21 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 398.0
TLS3_k127_7877768_22 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 412.0
TLS3_k127_7877768_23 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 397.0
TLS3_k127_7877768_24 polyphosphate kinase 2 K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 400.0
TLS3_k127_7877768_25 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 393.0
TLS3_k127_7877768_26 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 381.0
TLS3_k127_7877768_27 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 302.0
TLS3_k127_7877768_28 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001029 297.0
TLS3_k127_7877768_29 HutD K09975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000245 280.0
TLS3_k127_7877768_3 lysine biosynthetic process via aminoadipic acid - - - 2.676e-310 968.0
TLS3_k127_7877768_30 SET domain K07117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001897 261.0
TLS3_k127_7877768_31 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000005208 228.0
TLS3_k127_7877768_32 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000007125 218.0
TLS3_k127_7877768_33 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000001904 204.0
TLS3_k127_7877768_34 Protein of unknown function (DUF1439) - - - 0.00000000000000000000000000000000000000000000000001014 186.0
TLS3_k127_7877768_35 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.00000000000000000000000000000000000000000000000007393 185.0
TLS3_k127_7877768_36 - - - - 0.000000000000000000000000000000000000000000000287 175.0
TLS3_k127_7877768_37 Belongs to the bacterial histone-like protein family - - - 0.000000000000000000000000000000000000000000242 168.0
TLS3_k127_7877768_38 competence protein ComEA K02237 - - 0.000000000000000000000000000001107 127.0
TLS3_k127_7877768_39 Pathogenicity locus - - - 0.00000000000000000000000000001341 122.0
TLS3_k127_7877768_4 Cysteine desulfurase activator complex subunit SufB K09014 - - 5.567e-292 910.0
TLS3_k127_7877768_40 ACT domain K09964 - - 0.0000000000000000000000001325 123.0
TLS3_k127_7877768_41 Transglycosylase associated protein - - - 0.0000000000000000000000001655 108.0
TLS3_k127_7877768_44 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0000755 52.0
TLS3_k127_7877768_5 peptidase M20 - - - 2.579e-271 846.0
TLS3_k127_7877768_6 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 7.033e-258 811.0
TLS3_k127_7877768_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 3.208e-224 699.0
TLS3_k127_7877768_8 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 1.642e-217 688.0
TLS3_k127_7877768_9 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 597.0
TLS3_k127_7890729_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 4.485e-210 670.0
TLS3_k127_7890729_1 Belongs to the peptidase M17 family K01255 - 3.4.11.1 1.186e-205 650.0
TLS3_k127_7890729_2 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 488.0
TLS3_k127_7890729_3 Hydrolase K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 322.0
TLS3_k127_7890729_4 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001082 285.0
TLS3_k127_7890729_5 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000219 250.0
TLS3_k127_7890729_6 - - - - 0.00000000000000000000000000000000000000000000000001053 192.0
TLS3_k127_7890729_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000001808 158.0
TLS3_k127_7908473_0 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 374.0
TLS3_k127_7908473_1 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 306.0
TLS3_k127_7908473_2 haloacid dehalogenase K07025 - - 0.000000000007246 67.0
TLS3_k127_7930378_0 GGDEF domain - - - 2.066e-309 964.0
TLS3_k127_7930378_1 aminopeptidase K01262 - 3.4.11.9 3.569e-250 776.0
TLS3_k127_7930378_10 Belongs to the UPF0149 family K09895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004321 242.0
TLS3_k127_7930378_11 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000005375 191.0
TLS3_k127_7930378_12 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000000007546 135.0
TLS3_k127_7930378_13 NADP transhydrogenase K00324 - 1.6.1.2 0.000000000000000000000000000000666 126.0
TLS3_k127_7930378_14 TIGRFAM TIGR02449 family protein K09892 - - 0.0000000000000000001109 105.0
TLS3_k127_7930378_2 Protein of unknown function (DUF1631) - - - 5.292e-238 760.0
TLS3_k127_7930378_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 575.0
TLS3_k127_7930378_4 Exodeoxyribonuclease IX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 477.0
TLS3_k127_7930378_5 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 364.0
TLS3_k127_7930378_6 DNA mismatch repair protein MutT K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 307.0
TLS3_k127_7930378_7 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002387 267.0
TLS3_k127_7930378_8 EVE domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000169 255.0
TLS3_k127_7930378_9 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003858 276.0
TLS3_k127_7945499_0 - - - - 8.292e-239 746.0
TLS3_k127_7945499_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.328e-218 687.0
TLS3_k127_7945499_2 Belongs to the Orn Lys Arg decarboxylase class-II family K12526 - 2.7.2.4,4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 405.0
TLS3_k127_7945499_3 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 326.0
TLS3_k127_7964733_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 2.939e-245 769.0
TLS3_k127_7964733_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 8.619e-214 671.0
TLS3_k127_7964733_10 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 297.0
TLS3_k127_7964733_11 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 291.0
TLS3_k127_7964733_12 Belongs to the DnaA family. HdA subfamily K10763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001472 302.0
TLS3_k127_7964733_13 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001953 283.0
TLS3_k127_7964733_14 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002535 273.0
TLS3_k127_7964733_15 - - - - 0.000000000000000000000000000000000000000000000000000000000003126 213.0
TLS3_k127_7964733_16 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000006431 203.0
TLS3_k127_7964733_17 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.0000000000000000000000000000000000000000000000007937 189.0
TLS3_k127_7964733_18 - - - - 0.000000000000000000000000000000000000000000000002819 186.0
TLS3_k127_7964733_19 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000000000000000000000000000000000000004412 168.0
TLS3_k127_7964733_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 7.556e-194 611.0
TLS3_k127_7964733_20 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000000000001767 139.0
TLS3_k127_7964733_21 modulation protein K05808 - - 0.0000006805 52.0
TLS3_k127_7964733_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 602.0
TLS3_k127_7964733_4 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 516.0
TLS3_k127_7964733_5 Phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 498.0
TLS3_k127_7964733_6 abc transporter atp-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 435.0
TLS3_k127_7964733_7 protein conserved in bacteria K09938 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 439.0
TLS3_k127_7964733_8 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 450.0
TLS3_k127_7964733_9 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 358.0
TLS3_k127_801300_0 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 317.0
TLS3_k127_801300_1 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000005938 223.0
TLS3_k127_801300_2 PFAM TPR repeat-containing protein - - - 0.00000000000000001381 88.0
TLS3_k127_8078331_0 AAA ATPase domain K12132 - 2.7.11.1 2.05e-304 965.0
TLS3_k127_8078331_1 Inclusion body protein - - - 0.00000000000000000000000000000000000000000000004987 174.0
TLS3_k127_8078331_2 - - - - 0.0000000000000000000000009291 112.0
TLS3_k127_8185590_0 amidohydrolase - - - 5.365e-220 706.0
TLS3_k127_8185590_1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile K01241 - 3.2.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 499.0
TLS3_k127_8185590_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000001753 164.0
TLS3_k127_8185590_3 Bacterial protein of unknown function (DUF924) - - - 0.000000003365 65.0
TLS3_k127_8197621_0 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 415.0
TLS3_k127_8197621_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 386.0
TLS3_k127_8197621_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 378.0
TLS3_k127_8197621_3 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000008334 198.0
TLS3_k127_8197621_4 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000003812 96.0
TLS3_k127_820077_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 4.549e-271 850.0
TLS3_k127_820077_1 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 4.444e-210 657.0
TLS3_k127_820077_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 554.0
TLS3_k127_820077_3 Predicted nucleotidyltransferase K07074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 297.0
TLS3_k127_820077_4 PTS system fructose IIA component family protein K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000000000000000001297 205.0
TLS3_k127_820077_5 phosphocarrier protein HPr K11189 - - 0.000000000000000000000000000000000001086 141.0
TLS3_k127_8200832_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1133.0
TLS3_k127_8200832_1 pseudouridylate synthase K06175 - 5.4.99.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 336.0
TLS3_k127_8208444_0 Putative diguanylate phosphodiesterase - - - 5.944e-307 955.0
TLS3_k127_8208444_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 2.334e-270 839.0
TLS3_k127_8208444_10 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 421.0
TLS3_k127_8208444_11 Belongs to the inositol monophosphatase superfamily K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 417.0
TLS3_k127_8208444_12 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 390.0
TLS3_k127_8208444_13 Pit accessory protein K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 345.0
TLS3_k127_8208444_14 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 342.0
TLS3_k127_8208444_15 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001156 279.0
TLS3_k127_8208444_16 Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001325 281.0
TLS3_k127_8208444_17 exopolysaccharide synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000003648 243.0
TLS3_k127_8208444_18 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000007873 213.0
TLS3_k127_8208444_19 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000000000000000000001527 168.0
TLS3_k127_8208444_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 6.228e-260 808.0
TLS3_k127_8208444_20 MAPEG family - - - 0.0000000000000000000000000000000000000006347 155.0
TLS3_k127_8208444_21 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00663,K03790 - 2.3.1.128,2.3.1.82 0.000000000000000000000000009858 116.0
TLS3_k127_8208444_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 3.275e-235 743.0
TLS3_k127_8208444_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 1.493e-219 685.0
TLS3_k127_8208444_5 phosphate transporter K03306 - - 6.797e-207 649.0
TLS3_k127_8208444_6 Hemolysins and related proteins containing CBS domains K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 601.0
TLS3_k127_8208444_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 582.0
TLS3_k127_8208444_8 metallo-beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 527.0
TLS3_k127_8208444_9 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 447.0
TLS3_k127_8217152_0 Catalyzes the reversible formation of glyoxylate and succinate from isocitrate K01637 - 4.1.3.1 2.192e-259 805.0
TLS3_k127_8217152_1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle K01638 - 2.3.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 421.0
TLS3_k127_8217152_2 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000002419 212.0
TLS3_k127_8217152_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000004446 186.0
TLS3_k127_8217152_5 - - - - 0.0000007465 57.0
TLS3_k127_8217152_6 - - - - 0.00000121 56.0
TLS3_k127_8233689_0 TonB-dependent receptor - - - 0.0 1030.0
TLS3_k127_8233689_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 1.602e-238 749.0
TLS3_k127_8233689_10 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 469.0
TLS3_k127_8233689_11 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 450.0
TLS3_k127_8233689_12 C4-dicarboxylate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 442.0
TLS3_k127_8233689_13 abc transporter atp-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 427.0
TLS3_k127_8233689_14 ABC transporter substrate-binding protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 399.0
TLS3_k127_8233689_15 porphyrin biosynthesis protein K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 396.0
TLS3_k127_8233689_16 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 366.0
TLS3_k127_8233689_17 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 359.0
TLS3_k127_8233689_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 316.0
TLS3_k127_8233689_19 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 296.0
TLS3_k127_8233689_2 Belongs to the type-B carboxylesterase lipase family K03929 - - 3.939e-229 738.0
TLS3_k127_8233689_20 protein conserved in bacteria K09912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 290.0
TLS3_k127_8233689_21 HemX, putative uroporphyrinogen-III C-methyltransferase K02496 - 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 299.0
TLS3_k127_8233689_22 Acyl transferase domain K00645,K15327,K15329,K15469 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 293.0
TLS3_k127_8233689_23 NAD(P)H-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000366 274.0
TLS3_k127_8233689_24 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001567 274.0
TLS3_k127_8233689_25 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002519 275.0
TLS3_k127_8233689_26 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002018 244.0
TLS3_k127_8233689_27 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004398 254.0
TLS3_k127_8233689_28 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000001221 233.0
TLS3_k127_8233689_29 Rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000207 207.0
TLS3_k127_8233689_3 Pectate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 602.0
TLS3_k127_8233689_30 Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N- methyltransferase family K11438 - 2.1.1.321 0.0000000000000000000000000000000000000000000000000000000002947 232.0
TLS3_k127_8233689_31 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000007065 205.0
TLS3_k127_8233689_32 CorA-like Mg2+ transporter protein - - - 0.0000000000000000000000000000000000000000000000000001652 200.0
TLS3_k127_8233689_33 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000000000000000000003537 204.0
TLS3_k127_8233689_34 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.00000000000000000000000000000000000000000000000001112 184.0
TLS3_k127_8233689_35 thioesterase - - - 0.000000000000000000000000000000000000000000000001799 178.0
TLS3_k127_8233689_36 - - - - 0.00000000000000000000000000000000000000000001398 168.0
TLS3_k127_8233689_37 - - - - 0.00000000000000000000000000000000000000003004 157.0
TLS3_k127_8233689_38 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000001182 126.0
TLS3_k127_8233689_39 - - - - 0.0000000000000002394 87.0
TLS3_k127_8233689_4 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 593.0
TLS3_k127_8233689_40 CVNH domain - - - 0.00000008358 63.0
TLS3_k127_8233689_5 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 581.0
TLS3_k127_8233689_6 Multidrug ABC transporter ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 520.0
TLS3_k127_8233689_7 abc transporter, permease K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 519.0
TLS3_k127_8233689_8 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 489.0
TLS3_k127_8233689_9 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 488.0
TLS3_k127_824655_0 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 307.0
TLS3_k127_824655_1 Zn_pept - - - 0.0000000000000000000000000000002957 143.0
TLS3_k127_824655_2 Subtilase family - - - 0.00000000000000000263 101.0
TLS3_k127_824655_3 PFAM von Willebrand factor type A K01337 - 3.4.21.50 0.00000000006092 76.0
TLS3_k127_8269955_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0 1113.0
TLS3_k127_8269955_1 membrane - - - 2.053e-194 616.0
TLS3_k127_8269955_10 protein conserved in bacteria - - - 0.0000000000000000000000000006408 114.0
TLS3_k127_8269955_11 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000002342 107.0
TLS3_k127_8269955_12 membrane - - - 0.000006302 56.0
TLS3_k127_8269955_2 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 602.0
TLS3_k127_8269955_3 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 529.0
TLS3_k127_8269955_4 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 509.0
TLS3_k127_8269955_5 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 487.0
TLS3_k127_8269955_6 Mitochondrial fission ELM1 K07276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 368.0
TLS3_k127_8269955_7 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 324.0
TLS3_k127_8269955_8 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 293.0
TLS3_k127_8269955_9 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000302 287.0
TLS3_k127_8311812_0 Microcystin-dependent protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 290.0
TLS3_k127_8311812_1 Phage Tail Collar Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001234 267.0
TLS3_k127_8311812_2 Microcystin-dependent protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008513 261.0
TLS3_k127_8311812_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000007854 213.0
TLS3_k127_8311812_4 - - - - 0.000000000000000000000000000000000000007826 152.0
TLS3_k127_834184_0 AMP-dependent synthetase - - - 6.509e-289 945.0
TLS3_k127_834184_1 non-ribosomal peptide synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 466.0
TLS3_k127_834184_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000371 287.0
TLS3_k127_834184_3 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000559 263.0
TLS3_k127_834184_4 non-ribosomal peptide synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000582 245.0
TLS3_k127_834184_5 Non-ribosomal peptide synthetase modules and related proteins K04780 - - 0.0000000000000000000000000000000000006572 154.0
TLS3_k127_8377371_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.205e-239 748.0
TLS3_k127_8377371_1 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 6.728e-196 617.0
TLS3_k127_8377371_10 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000000000000000000001108 206.0
TLS3_k127_8377371_11 chemotaxis signal transduction protein K06598 - - 0.0000000000000000000000000000000000000000000000000000000507 204.0
TLS3_k127_8377371_12 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000000000000000000001149 183.0
TLS3_k127_8377371_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 586.0
TLS3_k127_8377371_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 529.0
TLS3_k127_8377371_4 Nucleoside triphosphate K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 403.0
TLS3_k127_8377371_5 nucleotidase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 382.0
TLS3_k127_8377371_6 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 370.0
TLS3_k127_8377371_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 340.0
TLS3_k127_8377371_8 ADP-ribose diphosphatase K08312 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002004 279.0
TLS3_k127_8377371_9 protein-glutamate methylesterase K06597 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002116 262.0
TLS3_k127_8426115_0 General secretion pathway protein K02454 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 1.163e-306 949.0
TLS3_k127_8426115_1 General secretion pathway protein K02453 - - 1.61e-264 836.0
TLS3_k127_8426115_10 Type II secretion system protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 348.0
TLS3_k127_8426115_11 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 294.0
TLS3_k127_8426115_12 Erythromycin esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001189 265.0
TLS3_k127_8426115_13 General secretion pathway protein K02462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000316 246.0
TLS3_k127_8426115_14 transcriptional K13639 - - 0.000000000000000000000000000000000000000000000000000000000000000000003669 236.0
TLS3_k127_8426115_15 General secretion pathway protein K02459 - - 0.00000000000000000000000000000000000000000000000000000000000008958 224.0
TLS3_k127_8426115_16 General secretion pathway protein K02463 - - 0.00000000000000000000000000000000000000000000000000000000001703 215.0
TLS3_k127_8426115_17 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000000000008133 224.0
TLS3_k127_8426115_18 Type II transport protein GspH K02457 - - 0.0000000000000000000000000000000000000000000001303 174.0
TLS3_k127_8426115_19 Domain of unknown function (DUF4426) - - - 0.00000000000000000000000000000000000000000002095 169.0
TLS3_k127_8426115_2 twitching motility protein K02670 - - 1.191e-231 719.0
TLS3_k127_8426115_20 General secretion pathway protein K02456 - - 0.00000000000000000000000000000000000004231 149.0
TLS3_k127_8426115_21 Thioesterase superfamily - - - 0.000000000000000000000000000000000000186 153.0
TLS3_k127_8426115_22 Prokaryotic N-terminal methylation motif K02458 - - 0.00000000000000000000000000000000000505 149.0
TLS3_k127_8426115_24 Major Facilitator Superfamily - - - 0.000000000006861 76.0
TLS3_k127_8426115_3 twitching motility protein K02669 - - 5.815e-211 663.0
TLS3_k127_8426115_4 General secretion pathway protein K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 2.939e-194 612.0
TLS3_k127_8426115_5 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 440.0
TLS3_k127_8426115_6 Glycosyl transferase K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 398.0
TLS3_k127_8426115_7 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 399.0
TLS3_k127_8426115_8 General secretion pathway protein K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 382.0
TLS3_k127_8426115_9 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 364.0
TLS3_k127_847308_0 Peptidase C13 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 312.0
TLS3_k127_847308_1 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 0.000000000000000000000000000000000000000000000000000000000000000000000000753 248.0
TLS3_k127_8540672_0 elongation factor G K02355 - - 0.0 1103.0
TLS3_k127_8540672_1 COG2217 Cation transport ATPase K01533 - 3.6.3.4 1.046e-315 986.0
TLS3_k127_8540672_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 324.0
TLS3_k127_8540672_11 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 306.0
TLS3_k127_8540672_12 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 327.0
TLS3_k127_8540672_14 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001814 271.0
TLS3_k127_8540672_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K11050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002598 265.0
TLS3_k127_8540672_16 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000001576 251.0
TLS3_k127_8540672_17 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000002295 230.0
TLS3_k127_8540672_18 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000000000000000000005866 224.0
TLS3_k127_8540672_19 FixH K09926 - - 0.00000000000000000000000000000000000000000003524 171.0
TLS3_k127_8540672_2 Conserved repeat domain - - - 7.426e-295 942.0
TLS3_k127_8540672_20 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000004222 162.0
TLS3_k127_8540672_21 - - - - 0.000000000000000000000000000000000009851 156.0
TLS3_k127_8540672_22 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.0000000000000000000000000000008099 137.0
TLS3_k127_8540672_23 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000002265 141.0
TLS3_k127_8540672_24 ABC-2 type transporter K01992 - - 0.0000000000000000000000000002693 132.0
TLS3_k127_8540672_25 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000726 110.0
TLS3_k127_8540672_26 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000757 108.0
TLS3_k127_8540672_28 Pfam ATP-grasp domain K01955 - 6.3.5.5 0.00000000000000008594 94.0
TLS3_k127_8540672_29 Cytochrome oxidase maturation protein - - - 0.000000000000001822 86.0
TLS3_k127_8540672_3 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 8.96e-272 848.0
TLS3_k127_8540672_30 PFAM thioesterase superfamily K07107 - - 0.0000000000004303 81.0
TLS3_k127_8540672_31 elongation factor G K02355 - - 0.000000000006256 69.0
TLS3_k127_8540672_32 MacB-like periplasmic core domain - - - 0.00000000009379 74.0
TLS3_k127_8540672_33 MacB-like periplasmic core domain K02004 - - 0.0000000001232 73.0
TLS3_k127_8540672_34 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.0000000003584 64.0
TLS3_k127_8540672_35 Flavin containing amine oxidoreductase - - - 0.0000000003665 74.0
TLS3_k127_8540672_36 - - - - 0.00000003787 66.0
TLS3_k127_8540672_37 Domain of unknown function (DUF4872) - - - 0.000000844 62.0
TLS3_k127_8540672_4 3HB-oligomer hydrolase (3HBOH) K07518 - 3.1.1.22 8.787e-228 719.0
TLS3_k127_8540672_5 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 2.004e-221 698.0
TLS3_k127_8540672_6 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 4.991e-212 668.0
TLS3_k127_8540672_7 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 448.0
TLS3_k127_8540672_8 LuxR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 373.0
TLS3_k127_8540672_9 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 359.0
TLS3_k127_867091_0 penicillin-binding protein K05367 - 2.4.1.129 0.0 1161.0
TLS3_k127_867091_1 Large extracellular alpha-helical protein K06894 - - 1.307e-235 737.0
TLS3_k127_867091_2 Quinone oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 523.0
TLS3_k127_867091_3 Cytochrome C biogenesis protein K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 454.0
TLS3_k127_867091_4 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 413.0
TLS3_k127_867091_5 E3 component of 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 412.0
TLS3_k127_867091_6 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 355.0
TLS3_k127_867091_7 Peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000001073 240.0
TLS3_k127_867091_8 Chemotaxis protein CheY K02658 - - 0.000000000000000000000000000000000000000000000000000000000000007566 219.0
TLS3_k127_867091_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000001616 216.0
TLS3_k127_870186_0 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease K03694 - - 0.0 1295.0
TLS3_k127_870186_1 Cell division protein ftsk K03466 - - 0.0 1147.0
TLS3_k127_870186_10 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 336.0
TLS3_k127_870186_11 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007575 270.0
TLS3_k127_870186_12 PFAM Response regulator receiver domain K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004596 274.0
TLS3_k127_870186_13 High frequency lysogenization protein HflD homolog K07153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004977 245.0
TLS3_k127_870186_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000001034 224.0
TLS3_k127_870186_15 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000283 203.0
TLS3_k127_870186_16 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000000000112 194.0
TLS3_k127_870186_17 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000007745 203.0
TLS3_k127_870186_18 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000001736 162.0
TLS3_k127_870186_19 - - - - 0.0000000000000000000000000000000000000000003671 165.0
TLS3_k127_870186_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 595.0
TLS3_k127_870186_20 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000003108 149.0
TLS3_k127_870186_21 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000001123 146.0
TLS3_k127_870186_22 Dihaem cytochrome c - - - 0.0000000000000000000000000000000002198 144.0
TLS3_k127_870186_23 HNH nucleases - - - 0.000000000000000000000000003311 119.0
TLS3_k127_870186_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 598.0
TLS3_k127_870186_4 protein conserved in bacteria K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 578.0
TLS3_k127_870186_5 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 485.0
TLS3_k127_870186_6 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 447.0
TLS3_k127_870186_7 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 412.0
TLS3_k127_870186_8 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 390.0
TLS3_k127_870186_9 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 359.0
TLS3_k127_873072_0 Histidine ammonia-lyase K01745 - 4.3.1.3 1.934e-318 1000.0
TLS3_k127_873072_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 9.3e-241 751.0
TLS3_k127_873072_10 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 541.0
TLS3_k127_873072_11 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 490.0
TLS3_k127_873072_12 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 441.0
TLS3_k127_873072_13 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 424.0
TLS3_k127_873072_14 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 325.0
TLS3_k127_873072_15 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 312.0
TLS3_k127_873072_16 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 296.0
TLS3_k127_873072_17 Glutathione S-transferase, C-terminal domain K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001844 262.0
TLS3_k127_873072_18 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007462 252.0
TLS3_k127_873072_19 SufE protein probably involved in Fe-S center assembly K02426 - - 0.00000000000000000000000000000000000000000000000000000000000000000258 229.0
TLS3_k127_873072_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.562e-238 742.0
TLS3_k127_873072_20 Acetyltransferases including N-acetylases of ribosomal proteins K22479 - - 0.000000000000000000000000000000000000000000000000000000005168 217.0
TLS3_k127_873072_21 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000744 173.0
TLS3_k127_873072_22 protein, YerC YecD - - - 0.0000000000000000000000000000000000000003688 151.0
TLS3_k127_873072_23 Outer membrane lipoprotein - - - 0.000000000000000000000000001001 117.0
TLS3_k127_873072_24 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000001578 125.0
TLS3_k127_873072_25 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000006638 93.0
TLS3_k127_873072_26 Resolvase, N terminal domain - - - 0.00000002001 59.0
TLS3_k127_873072_27 - - - - 0.00002656 46.0
TLS3_k127_873072_3 Acetylglutamate kinase K22478 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 2.282e-235 735.0
TLS3_k127_873072_4 histidyl-tRNA synthetase K01892 - 6.1.1.21 5.333e-234 734.0
TLS3_k127_873072_5 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 3.368e-233 727.0
TLS3_k127_873072_6 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 1.773e-203 638.0
TLS3_k127_873072_7 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 615.0
TLS3_k127_873072_8 Acetylornithine deacetylase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 587.0
TLS3_k127_873072_9 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 523.0
TLS3_k127_873119_0 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 1.259e-313 969.0
TLS3_k127_873119_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 8.563e-303 938.0
TLS3_k127_873119_10 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 417.0
TLS3_k127_873119_11 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 384.0
TLS3_k127_873119_12 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 332.0
TLS3_k127_873119_13 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000002062 231.0
TLS3_k127_873119_14 Bacterial PH domain K09167 - - 0.000000000000000000000000000000000001179 146.0
TLS3_k127_873119_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 2.57e-252 798.0
TLS3_k127_873119_3 Belongs to the UPF0061 (SELO) family - - - 3.196e-252 786.0
TLS3_k127_873119_4 dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 598.0
TLS3_k127_873119_5 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 561.0
TLS3_k127_873119_6 Nacht domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 528.0
TLS3_k127_873119_7 Bacterial PH domain K08981 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 517.0
TLS3_k127_873119_8 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 432.0
TLS3_k127_873119_9 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 432.0
TLS3_k127_915049_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.831e-286 882.0
TLS3_k127_915049_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.083e-254 788.0
TLS3_k127_915049_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 5.059e-216 692.0
TLS3_k127_915049_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 508.0
TLS3_k127_915049_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 494.0
TLS3_k127_915049_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000001695 216.0
TLS3_k127_915049_6 GtrA-like protein - - - 0.00000000000000000000000000000000000000000000000000000004291 202.0
TLS3_k127_92925_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 1.663e-302 940.0
TLS3_k127_92925_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.351e-281 874.0
TLS3_k127_92925_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 565.0
TLS3_k127_92925_3 Acetolactate synthase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000009981 157.0
TLS3_k127_980519_0 Circularly permuted ATP-grasp type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 581.0
TLS3_k127_980519_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 471.0
TLS3_k127_980519_2 Proteasome subunit K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 363.0
TLS3_k127_986363_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1430.0
TLS3_k127_986363_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 1.72e-229 718.0
TLS3_k127_986363_10 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001533 289.0
TLS3_k127_986363_11 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003151 276.0
TLS3_k127_986363_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000006039 243.0
TLS3_k127_986363_13 Biopolymer K03559 - - 0.0000000000000000000000000000000000000000000000000000000000001109 214.0
TLS3_k127_986363_14 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000000000000001958 191.0
TLS3_k127_986363_15 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000256 122.0
TLS3_k127_986363_16 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000002655 86.0
TLS3_k127_986363_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 3.336e-206 664.0
TLS3_k127_986363_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 5.116e-201 630.0
TLS3_k127_986363_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 605.0
TLS3_k127_986363_5 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 534.0
TLS3_k127_986363_6 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 478.0
TLS3_k127_986363_7 Biopolymer transporter ExbB K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 435.0
TLS3_k127_986363_8 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 377.0
TLS3_k127_986363_9 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 334.0